LOCUS       DAVKMJ010000001        74828 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000001 DAVKMJ010000000
VERSION     DAVKMJ010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 74828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74828
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.001"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..780
                     /locus_tag="VW348_000001"
     CDS             <1..780
                     /locus_tag="VW348_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU9744990.1"
                     /translation="QFGYTNHRIKLILSNEDLGATNARNIGIKNSRGKYISFLDDDDE
                     YMPDRILKLMACFKKSRMKNLALVYSYGIIIYPNGTREEEKTDFVGNPLFVQMVHNIA
                     GTSFWLCKKEVLELINGFEKIDSHQDGVVLLKLLAQGYQIDIVREFLVNYYAHSKENG
                     ITGVTQKTINADEEYYNYCRKYFNLLSFNERILVTKKYYSLNIKRLLLIGDKCKALKV
                     IKKAREEKIFNEFLFLKYMLLYYFGFFYCIYDNYVQLKFRK"
     gene            790..2406
                     /locus_tag="VW348_000002"
     CDS             790..2406
                     /locus_tag="VW348_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9744991.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTSQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            2667..3095
                     /locus_tag="VW348_000003"
     CDS             2667..3095
                     /locus_tag="VW348_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9744992.1"
                     /translation="MSEIVEMSKKISNLNDKKEFHKKNCELRFQDSVLDNINSVPGTT
                     HLFSCLNIQTLVKIILYIFRYNSCMKIFNFRDKELIFFNKIVNGLIQNIEENLEDDIE
                     RILKYLYICLFNEIFIIKNKVNFFDDVEFNQTLSEFLDKL"
     gene            3107..3856
                     /locus_tag="VW348_000004"
     CDS             3107..3856
                     /locus_tag="VW348_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEU9744993.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            3869..5041
                     /locus_tag="VW348_000005"
     CDS             3869..5041
                     /locus_tag="VW348_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEU9744994.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIAIPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     FFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFEFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFTKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            5436..6299
                     /locus_tag="VW348_000006"
     CDS             5436..6299
                     /locus_tag="VW348_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU9744995.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACDGLTASQLSKFELGQSM
                     LSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKVVDRFAHQDIAGLEQLLEEV
                     EQEQMAETYRRLNAIVIKDAIHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCN
                     TLPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFLYIPIFE
                     AELESMLRPYDVFEKVSWQFLKKMSVFLQTKGSNQKEIERFTQSLQVLENPQLTSLFE
                     LRLQQYKKLID"
     gene            6585..6782
                     /locus_tag="VW348_000007"
     CDS             6585..6782
                     /locus_tag="VW348_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEU9744996.1"
                     /translation="MLNLQFAETMELTEAELETGYGGEFGNNAVIPAGAWGGLGTSWS
                     ITNFWKKYFNHDSSTVNRRHY"
     gene            6850..7515
                     /locus_tag="VW348_000008"
     CDS             6850..7515
                     /locus_tag="VW348_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9744997.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            7587..8813
                     /locus_tag="VW348_000009"
     CDS             7587..8813
                     /locus_tag="VW348_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9744998.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLT
                     ILLITISETLPQILQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(9163..9240)
                     /locus_tag="VW348_000010"
                     /pseudo
     CDS             complement(9163..9240)
                     /locus_tag="VW348_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            9311..9967
                     /locus_tag="VW348_000011"
     CDS             9311..9967
                     /locus_tag="VW348_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEU9744999.1"
                     /translation="MPTALGYVSIGLACGIIGAPYVTLVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            9957..10280
                     /locus_tag="VW348_000012"
     CDS             9957..10280
                     /locus_tag="VW348_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEU9745000.1"
                     /translation="MVSKYLLLAVIFSGLVTWIPRMIPFILVKHKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            10383..11213
                     /locus_tag="VW348_000013"
     CDS             10383..11213
                     /locus_tag="VW348_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9745001.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYNVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            11367..12221
                     /locus_tag="VW348_000014"
     CDS             11367..12221
                     /locus_tag="VW348_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU9745002.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            12321..13694
                     /locus_tag="VW348_000015"
     CDS             12321..13694
                     /locus_tag="VW348_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEU9745003.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            13687..14748
                     /locus_tag="VW348_000016"
     CDS             13687..14748
                     /locus_tag="VW348_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEU9745004.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSELSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGSSTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            14750..15442
                     /locus_tag="VW348_000017"
     CDS             14750..15442
                     /locus_tag="VW348_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9745005.1"
                     /translation="MESLIQTYLPNVYKMGWSGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAIPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(15471..16040)
                     /locus_tag="VW348_000018"
     CDS             complement(15471..16040)
                     /locus_tag="VW348_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU9745006.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            16175..16789
                     /locus_tag="VW348_000019"
     CDS             16175..16789
                     /locus_tag="VW348_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU9745007.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKILLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            16791..18437
                     /locus_tag="VW348_000020"
     CDS             16791..18437
                     /locus_tag="VW348_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9745008.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            18449..19735
                     /locus_tag="VW348_000021"
     CDS             18449..19735
                     /locus_tag="VW348_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9745009.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISGQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLTSFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            19787..20320
                     /locus_tag="VW348_000022"
     CDS             19787..20320
                     /locus_tag="VW348_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9745010.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            20398..20868
                     /gene="nrdI"
                     /locus_tag="VW348_000023"
     CDS             20398..20868
                     /gene="nrdI"
                     /locus_tag="VW348_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEU9745011.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(21161..22423)
                     /locus_tag="VW348_000024"
     CDS             complement(21161..22423)
                     /locus_tag="VW348_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEU9745012.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIIIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            complement(22733..23191)
                     /locus_tag="VW348_000025"
     CDS             complement(22733..23191)
                     /locus_tag="VW348_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEU9745013.1"
                     /translation="MKKQVFHDAATGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWATIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(23188..23628)
                     /locus_tag="VW348_000026"
     CDS             complement(23188..23628)
                     /locus_tag="VW348_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9745014.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            24061..24927
                     /locus_tag="VW348_000027"
     CDS             24061..24927
                     /locus_tag="VW348_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9745015.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLNALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
     gene            25264..25821
                     /locus_tag="VW348_000028"
     CDS             25264..25821
                     /locus_tag="VW348_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase family
                     flavoprotein"
                     /protein_id="HEU9745016.1"
                     /translation="MDKKNLLVLVTGSVGASNVDTYLYYIKKFYNVKVILSENSKKFI
                     SKELISYFCDKVYDEIFVEEVVPHVFLPYESDLLLILPATANVIGKIANGIADDLVTA
                     TVLNFNKKIIFCPNMNSTMWDNHIVQRNVSILKELGHIFLFESKKTYEVGLRKAIDST
                     CSMLQPQSLVKELIKLENIVLEEGH"
     gene            26042..27148
                     /locus_tag="VW348_000029"
     CDS             26042..27148
                     /locus_tag="VW348_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HEU9745017.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGPA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPLITRLHFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFM
                     ENRLKEFFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVIT
                     LDTSIYTNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSI
                     VFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLTY"
     gene            27124..28515
                     /locus_tag="VW348_000030"
     CDS             27124..28515
                     /locus_tag="VW348_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745018.1"
                     /translation="MDKKLDILDKVKEYLGNKTTQILDNQYKEFLKLNDIRRAFGISE
                     KVLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNHSYRFLCSPIITDDFLN
                     TKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMSAIKLCLEILNSIFFKK
                     KIDLLYSTGYYETRFLLNNLAKSGISCYEVSNCELDKDKFYNVFMMEPNRADLTLQKT
                     DFKIVEYFVKYKNNSIKVVILDISYQGSNFKLVEFLEKFKFANVIIFVVRSLIKLDQM
                     GLELTNGGIIEVFIPNHLRKLKNFIEEEFNKFRNSHGANLSLYEYCLLDNSLTLKNDW
                     NYSDLVMKFTSNFYADIKDLFMENSDIEIIHEEGVPFVFLDLIGEGKKEYEMFFQWLN
                     FFYKQLGITLYARNSFGFRNLTVEYFGIIGTERYIFKICPGVYKGLSYYLMKFLLKSF
                     SNEYLKTTDEVNR"
     gene            28512..29690
                     /locus_tag="VW348_000031"
     CDS             28512..29690
                     /locus_tag="VW348_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9745019.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGR
                     VNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY
                     "
     gene            30115..30348
                     /locus_tag="VW348_000032"
     CDS             30115..30348
                     /locus_tag="VW348_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU9745020.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            30631..32580
                     /gene="mutL"
                     /locus_tag="VW348_000033"
     CDS             30631..32580
                     /gene="mutL"
                     /locus_tag="VW348_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEU9745021.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(32905..33372)
                     /locus_tag="VW348_000034"
     CDS             complement(32905..33372)
                     /locus_tag="VW348_000034"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEU9745022.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIAVAWIPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(33373..34578)
                     /locus_tag="VW348_000035"
     CDS             complement(33373..34578)
                     /locus_tag="VW348_000035"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEU9745023.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(34598..35233)
                     /gene="ribE"
                     /locus_tag="VW348_000036"
     CDS             complement(34598..35233)
                     /gene="ribE"
                     /locus_tag="VW348_000036"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEU9745024.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(35218..36318)
                     /gene="ribD"
                     /locus_tag="VW348_000037"
     CDS             complement(35218..36318)
                     /gene="ribD"
                     /locus_tag="VW348_000037"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEU9745025.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHYVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(36453..36567)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            36724..37317
                     /gene="ruvA"
                     /locus_tag="VW348_000038"
     CDS             36724..37317
                     /gene="ruvA"
                     /locus_tag="VW348_000038"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEU9745026.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            37327..37890
                     /locus_tag="VW348_000039"
     CDS             37327..37890
                     /locus_tag="VW348_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEU9745027.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            37887..38564
                     /locus_tag="VW348_000040"
     CDS             37887..38564
                     /locus_tag="VW348_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9745028.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIATYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVDYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(38719..39750)
                     /locus_tag="VW348_000041"
     CDS             complement(38719..39750)
                     /locus_tag="VW348_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEU9745029.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKVLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEEPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDNNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(40005..40688)
                     /locus_tag="VW348_000042"
     CDS             complement(40005..40688)
                     /locus_tag="VW348_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEU9745030.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(40700..41644)
                     /locus_tag="VW348_000043"
     CDS             complement(40700..41644)
                     /locus_tag="VW348_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU9745031.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            41776..44607
                     /gene="uvrA"
                     /locus_tag="VW348_000044"
     CDS             41776..44607
                     /gene="uvrA"
                     /locus_tag="VW348_000044"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEU9745032.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLREGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            44600..45661
                     /locus_tag="VW348_000045"
     CDS             44600..45661
                     /locus_tag="VW348_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU9745033.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLDLFPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            45793..46191
                     /gene="spx"
                     /locus_tag="VW348_000046"
     CDS             45793..46191
                     /gene="spx"
                     /locus_tag="VW348_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEU9745034.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            46257..46826
                     /locus_tag="VW348_000047"
     CDS             46257..46826
                     /locus_tag="VW348_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEU9745035.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLVGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            46913..47179
                     /locus_tag="VW348_000048"
     CDS             46913..47179
                     /locus_tag="VW348_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEU9745036.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            47183..47602
                     /gene="ruvX"
                     /locus_tag="VW348_000049"
     CDS             47183..47602
                     /gene="ruvX"
                     /locus_tag="VW348_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEU9745037.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            47618..47923
                     /locus_tag="VW348_000050"
     CDS             47618..47923
                     /locus_tag="VW348_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEU9745038.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            48336..49586
                     /locus_tag="VW348_000051"
     CDS             48336..49586
                     /locus_tag="VW348_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU9745039.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNLSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSCREFISDFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            49583..50140
                     /locus_tag="VW348_000052"
     CDS             49583..50140
                     /locus_tag="VW348_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEU9745040.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQPAQQNTNTANAGGNQNQAAPVQNQPVAQP
                     TDIDGTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKI
                     YTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            50286..51818
                     /gene="cls"
                     /locus_tag="VW348_000053"
     CDS             50286..51818
                     /gene="cls"
                     /locus_tag="VW348_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEU9745041.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGINLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            51896..52039
                     /locus_tag="VW348_000054"
     CDS             51896..52039
                     /locus_tag="VW348_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745042.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            52076..53614
                     /locus_tag="VW348_000055"
     CDS             52076..53614
                     /locus_tag="VW348_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU9745043.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFEFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            53734..55941
                     /gene="nrdD"
                     /locus_tag="VW348_000056"
     CDS             53734..55941
                     /gene="nrdD"
                     /locus_tag="VW348_000056"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEU9745044.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            55953..56093
                     /locus_tag="VW348_000057"
     CDS             55953..56093
                     /locus_tag="VW348_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745045.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            56137..56643
                     /locus_tag="VW348_000058"
     CDS             56137..56643
                     /locus_tag="VW348_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9745046.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNLASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            56636..57226
                     /gene="nrdG"
                     /locus_tag="VW348_000059"
     CDS             56636..57226
                     /gene="nrdG"
                     /locus_tag="VW348_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEU9745047.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLEFLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            57223..57840
                     /locus_tag="VW348_000060"
     CDS             57223..57840
                     /locus_tag="VW348_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEU9745048.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILALQASMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            58106..58414
                     /gene="rpsJ"
                     /locus_tag="VW348_000061"
     CDS             58106..58414
                     /gene="rpsJ"
                     /locus_tag="VW348_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEU9745049.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            58631..59257
                     /gene="rplC"
                     /locus_tag="VW348_000062"
     CDS             58631..59257
                     /gene="rplC"
                     /locus_tag="VW348_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEU9745050.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            59282..59905
                     /gene="rplD"
                     /locus_tag="VW348_000063"
     CDS             59282..59905
                     /gene="rplD"
                     /locus_tag="VW348_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEU9745051.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            59905..60201
                     /locus_tag="VW348_000064"
     CDS             59905..60201
                     /locus_tag="VW348_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEU9745052.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            60219..61052
                     /gene="rplB"
                     /locus_tag="VW348_000065"
     CDS             60219..61052
                     /gene="rplB"
                     /locus_tag="VW348_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEU9745053.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            61156..61437
                     /gene="rpsS"
                     /locus_tag="VW348_000066"
     CDS             61156..61437
                     /gene="rpsS"
                     /locus_tag="VW348_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEU9745054.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            61449..61793
                     /gene="rplV"
                     /locus_tag="VW348_000067"
     CDS             61449..61793
                     /gene="rplV"
                     /locus_tag="VW348_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEU9745055.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            61806..62459
                     /gene="rpsC"
                     /locus_tag="VW348_000068"
     CDS             61806..62459
                     /gene="rpsC"
                     /locus_tag="VW348_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEU9745056.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            62463..62876
                     /gene="rplP"
                     /locus_tag="VW348_000069"
     CDS             62463..62876
                     /gene="rplP"
                     /locus_tag="VW348_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEU9745057.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            62886..63092
                     /locus_tag="VW348_000070"
     CDS             62886..63092
                     /locus_tag="VW348_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEU9745058.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            63117..63377
                     /gene="rpsQ"
                     /locus_tag="VW348_000071"
     CDS             63117..63377
                     /gene="rpsQ"
                     /locus_tag="VW348_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEU9745059.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            63403..63771
                     /gene="rplN"
                     /locus_tag="VW348_000072"
     CDS             63403..63771
                     /gene="rplN"
                     /locus_tag="VW348_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEU9745060.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            63849..64154
                     /gene="rplX"
                     /locus_tag="VW348_000073"
     CDS             63849..64154
                     /gene="rplX"
                     /locus_tag="VW348_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEU9745061.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            64178..64720
                     /gene="rplE"
                     /locus_tag="VW348_000074"
     CDS             64178..64720
                     /gene="rplE"
                     /locus_tag="VW348_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEU9745062.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            64738..65007
                     /gene="rpsN"
                     /locus_tag="VW348_000075"
     CDS             64738..65007
                     /gene="rpsN"
                     /locus_tag="VW348_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEU9745063.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            65292..65690
                     /gene="rpsH"
                     /locus_tag="VW348_000076"
     CDS             65292..65690
                     /gene="rpsH"
                     /locus_tag="VW348_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEU9745064.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            65882..66418
                     /gene="rplF"
                     /locus_tag="VW348_000077"
     CDS             65882..66418
                     /gene="rplF"
                     /locus_tag="VW348_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEU9745065.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            66502..66858
                     /gene="rplR"
                     /locus_tag="VW348_000078"
     CDS             66502..66858
                     /gene="rplR"
                     /locus_tag="VW348_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEU9745066.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            66876..67370
                     /gene="rpsE"
                     /locus_tag="VW348_000079"
     CDS             66876..67370
                     /gene="rpsE"
                     /locus_tag="VW348_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEU9745067.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            67342..67566
                     /gene="rpmD"
                     /locus_tag="VW348_000080"
     CDS             67342..67566
                     /gene="rpmD"
                     /locus_tag="VW348_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEU9745068.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            67711..68151
                     /gene="rplO"
                     /locus_tag="VW348_000081"
     CDS             67711..68151
                     /gene="rplO"
                     /locus_tag="VW348_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEU9745069.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            68164..69474
                     /gene="secY"
                     /locus_tag="VW348_000082"
     CDS             68164..69474
                     /gene="secY"
                     /locus_tag="VW348_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEU9745070.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            69625..70263
                     /locus_tag="VW348_000083"
     CDS             69625..70263
                     /locus_tag="VW348_000083"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEU9745071.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGVINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            70380..70598
                     /gene="infA"
                     /locus_tag="VW348_000084"
     CDS             70380..70598
                     /gene="infA"
                     /locus_tag="VW348_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEU9745072.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            70623..70739
                     /gene="rpmJ"
                     /locus_tag="VW348_000085"
     CDS             70623..70739
                     /gene="rpmJ"
                     /locus_tag="VW348_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEU9745073.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            70757..71122
                     /gene="rpsM"
                     /locus_tag="VW348_000086"
     CDS             70757..71122
                     /gene="rpsM"
                     /locus_tag="VW348_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEU9745074.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            71140..71523
                     /gene="rpsK"
                     /locus_tag="VW348_000087"
     CDS             71140..71523
                     /gene="rpsK"
                     /locus_tag="VW348_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEU9745075.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            71566..72501
                     /locus_tag="VW348_000088"
     CDS             71566..72501
                     /locus_tag="VW348_000088"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEU9745076.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            72513..72899
                     /gene="rplQ"
                     /locus_tag="VW348_000089"
     CDS             72513..72899
                     /gene="rplQ"
                     /locus_tag="VW348_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEU9745077.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            73164..73430
                     /locus_tag="VW348_000090"
     CDS             73164..73430
                     /locus_tag="VW348_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEU9745078.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            73440..74777
                     /locus_tag="VW348_000091"
     CDS             73440..74777
                     /locus_tag="VW348_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEU9745079.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
BASE COUNT        22974 a        13260 c        16022 g        22572 t
ORIGIN      
        1 caatttggct atacaaatca tagaattaag ttaattttaa gtaatgaaga tttaggtgca
       61 actaatgcca gaaacatagg tataaaaaat tctagaggta agtatatatc atttttagac
      121 gatgatgatg aatatatgcc agatcgaatt ttaaagttga tggcttgttt taaaaagagt
      181 agaatgaaga atttagcttt agtttatagt tatggaataa taatttatcc aaatggtaca
      241 cgagaagagg agaagaccga ttttgttgga aatcccttgt ttgttcaaat ggttcacaat
      301 atagcaggta cgtcattttg gttgtgtaaa aaagaggtgc tagaattaat taatggtttt
      361 gagaaaatag attcacatca ggacggtgtt gttttattaa aactacttgc tcaaggatac
      421 caaattgata tagtgcgaga attcttggtg aattactacg ctcacagtaa agaaaacggt
      481 atcactggag tgacacaaaa aacaattaat gcagatgaag aatattataa ttactgtagg
      541 aaatatttta atttattgag tttcaacgag agaatattgg ttacaaagaa atattattct
      601 ttaaacataa agcggttact attaatagga gacaaatgca aggctttaaa agtaatcaag
      661 aaggcaagag aagaaaaaat ttttaacgaa tttctttttt tgaaatacat gttattatat
      721 tattttggtt ttttctattg tatatatgac aactatgttc aattaaaatt tagaaagtga
      781 gaaactattg tgtatactat tataaaatca aatataaaaa aatttagttt attaacgata
      841 tttattgttg ctggtcaatt attgctaatt tatgcagcaa ctattaatgc tctggtgttg
      901 aatgaattaa ttgcgatgaa tttagagcgg tttttgaaat tgtcaatcta ccaaatgatt
      961 gtctggtgtg ggataatatt ccttgactgg gtagtgaaaa attatcaggt tgaagtgatc
     1021 caagagttta atctagagat tcgaaataga gttgccacag acatctctaa ctctacctat
     1081 caagaatttc atagtaaatc atcaggaaca tatctttcgt ggctaaataa tgatgttcag
     1141 actttaaatg atcaggcttt taaacaactt tttttagtaa taaaaggaat ttctggtact
     1201 atatttgcag ttgtgactct taatcactat cattggtcat tgactgtagc caccttgttt
     1261 tcattaatga ttatgctact tgtaccaaaa atctttgcat cgaaaatgcg agaagttagt
     1321 ctaaatttaa ctagccaaaa tgaagctttt ttaaaatcta gtgagactat attgaatgga
     1381 tttgatgtgt tagcgtcctt gaatctttta tatgtattgc ctaagaaaat taaagaagca
     1441 ggaattttat taaagatggt tatacaaaga aagacaactg tagaaacgtt agcaggcgct
     1501 attagcttct ttctcaatat tttttttcag atatctctcg tttttttaac aggctatctt
     1561 gcaataaaag gaatagtgaa aattggtact attgaagcaa taggagcact aacaggtgtt
     1621 atttttacag cgctaggtga attaggaggt caattatcct ctattattgg tacgaagcct
     1681 atttttttaa aattgtattc aattaatcca attgagtcaa ataaaatgaa tgatatcgaa
     1741 ccaaatgagg tgaatagaga ttttccgtta tatgaagcaa aaaatatttg ctataagtat
     1801 ggagataaag aaatattaaa aaacttaaat ttttgttttc aacgtaatga aaagtattta
     1861 attttaggtg aaagtggaag cgggaaatct acattattaa aattattgaa tggctttttg
     1921 agagattata gtggagaatt gcgattctgc ggggatgata taaaaaaaac ctcctattta
     1981 aatatggttt cgaatgttct atatgtagat caaaaagctt atttgtttga aggtacgatt
     2041 agagataata ttttattgga agaaaattat actgatgaag aaatactaca gtctttagaa
     2101 caagttggtt tgagtgtaaa agattttcct aataacattt tagattatta tgttggtgat
     2161 gatgggagat tactgtcagg agggcagaaa caaaaaatta ctttagctag aggcctaatt
     2221 agaaataaga aaatagtatt aattgacgag ggaacttctg ctatcgatag gagaacttcg
     2281 ttagcgattg aacgtaagat attagataga gaggatttga ctgtcattat tgttacccat
     2341 gctccgcatc cggaacttaa acaatatttt actaagatat atcaatttcc aaaggatttt
     2401 atttaagaat ataggggagg gaaacatgag attctattgt gaagcttatg aggtaattac
     2461 tgaagagaaa aaagtatcat ttttttatgt agatgagaaa cccttaaggt atctgttatt
     2521 tgactatata tttctactag ttctagctaa aaaaaaatat cccaatctta tgaactgcac
     2581 cccaaaagtt agatttattc tgtctaactt ttggggtgca gttcattttg catagttttg
     2641 gcattcatcc tagatatcca tataaaatgt ctgagattgt tgaaatgtct aaaaaaatat
     2701 caaatctaaa cgataaaaaa gaatttcaca aaaagaactg tgagttgagg tttcaagata
     2761 gtgttcttga taacataaat agtgtcccgg gtacaactca tttatttagt tgtttaaata
     2821 ttcaaacatt agtaaaaatt attttatata tttttcgata caacagttgt atgaaaatat
     2881 ttaattttag agataaagag cttatctttt ttaataagat tgtaaatggg ctgatacaaa
     2941 atattgagga gaatttagag gatgatattg aaaggatatt gaaatattta tatatatgtt
     3001 tatttaacga aatattcatt attaagaata aggtgaattt ttttgatgat gtggaattta
     3061 atcagacact tagtgagttt ttagataaat tgtagaggga atggttatga gtaacaatac
     3121 taagtatatc tttttatctc cacatttaga tgacgcaatt ttttcctgtg gtgattatat
     3181 ttcaaaatta acttcagaag gagaaattgt acttgttatt actatatttt ctggttaccc
     3241 tttgagccaa cagctacagc cctctgctaa gcaatttcat aagttgtgta accttgggaa
     3301 atatccgatt gaagaaagga agaaagaaga caggttagct tgtgaacgtc tacaatgtga
     3361 ttttagacac ttatcgtact atgaatgtct ctataggaaa gatagaaatg gcaattttct
     3421 ataccgtcat atctatagtg aattaaaaaa tgaggacaca ttaaagaatg atatcataaa
     3481 agagctgtta atgcatttag acgataaatg tgtcgtatat tgtccgcttt cacttggtga
     3541 ccatgttgat catgtttttg tgaatagtat tggaagggcg cttgaattta tgcgttataa
     3601 agtaatatat tatgaggact tcccatatgt aagtgatagt agtatggtta gttatatggg
     3661 aaaaactaaa gaattaaaaa tgtatcaaga ggaacttgat gaaaaacatt atattgatag
     3721 aatatcatca atattgtgct ataaatctca gattttgata atctggaaat cagttgaaaa
     3781 acttttaaac aatattaaag agttgtattt aaggaatggg gcagcttatt ctattagatt
     3841 ttggattaag aaataaggaa gtagttttat gaatatagca gtaattggtt tggggcatgt
     3901 tgggctggcc tacgcgttac tatttgcatc taaatataaa gttgttgcat atgatataga
     3961 ttctgtaaaa ataaataatt taaaaaaggg cattcttcca tctaaaaatg aagagcttat
     4021 gaagtttttt tgcgagaata acttaaatat tacttttttt gatacatttt ctgaaattaa
     4081 aaataatatt gattattata ttattgcgat tccgacagat tatgatgaga aaattggtag
     4141 ttttaataca tatgaaatcg aacaaacggt atcgaagatt ctgagggtaa aacctaatgg
     4201 aaagattatt ttaaagtcaa cagttccgat cggcttttca aacaaattaa aaaggctgtt
     4261 tgatacaaaa aatatcattt ttgtccctga atttttgaga gaaggttgtt ctatatatga
     4321 taatttatat ccaagtcgca tagttgttgg agatgagaca gttgaaggaa gaaaaattgc
     4381 agagttgttc ctttcgatta gtactcatag tactgccaat attaaaaatg ttatgttagt
     4441 ttctcctact gaagcagaag caattaagct tttttctaac acattcttag ctctccgtgt
     4501 tgcttttttt aatgaactag atttttttgc tgagaggaga agtttaaatg ctgaagttgt
     4561 aataaaaggt gtttgtttag atccaagaat tggaaatttt tataataatc cttcttttga
     4621 atttggagga tattgtcttc ccaaagatac taaacaatta aaaaaagaat ttatagaaat
     4681 aaatgcccca gtgatagaag cgattgatat ttcaaacaca aatagaaaac agttcatagt
     4741 taaacaaata ttggaacgaa agccaaagat agtaggaata tataaattgg ggatgaaata
     4801 taattcagat aattacaaag agtcagctat tttaagtata attaatgaac tattgattgt
     4861 cggtataaaa attttagtat atgaaccaaa tttaaacgtt agtatagata acgtaatttt
     4921 tgaaaagaat tttgaactat ttacaaaaca aagtgatcta attgttgcaa atagatggga
     4981 taggggcctt gaagcttata aagataaagt ttacacaagg gggatctgga taagagatta
     5041 actattgata ttaaaaaggc aataatttat aaaatttgta caaaaaaatg ttaaattttc
     5101 acattttcat agtatactgt ttaatagaaa gtaggttctt tgtaaccgct ccattataaa
     5161 atcctttcac tcttccggta tgctattagg aaaaacataa ttggaggata ttttgagctc
     5221 acacctcatc gttccagtgg ctgttcccca agctcgtgta ctgcccaaaa aagttagaca
     5281 ttctatttag aacgaggatt gagttctgta ttgtacaagg ctcggtcctt ttagagtcag
     5341 cttaaggctg gctttttcaa tcaccaaagt gtcagaatgt tttgacaaat gaacacaaat
     5401 aatgatataa tatgcaaaag ctaggaggtg gtaggatgat tgaaaaaatg gaactggggg
     5461 aattttacaa ggaattacgt ttggcgagaa agctcaagca gtcagatgtg gcttgtgacg
     5521 ggctaacagc ttctcagttg tccaagtttg agctagggca gtccatgttg tctgctgata
     5581 agctcatatt agccatccaa gggatcaatg tgacctttga tgagtttggg cacaagctca
     5641 acaactatca agaatctcca catatgcaga ttggtagaaa ggttgtggat cgctttgctc
     5701 atcaagatat agctggctta gagcaactgt tggaggaagt cgagcaagaa cagatggcag
     5761 agacttatcg tcgtttgaat gctattgtaa tcaaagatgc catccactca ctagataaaa
     5821 gctacccact agcagaggag gatagcgagt ttttgaccac ctatctctat gctatcgagt
     5881 cttggacctg gtttgaactc tatctctttt gcaatactct gcccttcttg agcaatcaag
     5941 atctgatctt tttatcaacc tccttactcg aaaaatccaa agaatttaaa gagttagtac
     6001 acaatcgatt gtatatgaag caaggactct taaatatctt atcagaactc atggagcgaa
     6061 aacttttctt atacatccca atcttcgaag ccgagttgga gagcatgttg cgtccgtacg
     6121 atgtttttga aaaagtatcg tggcaatttt taaagaagat gagtgtcttt cttcaaacaa
     6181 agggaagcaa tcaaaaagag attgaacgct ttacccaatc tctgcaggta ttagaaaatc
     6241 cacaattaac atcccttttt gaattgcgtt tgcagcaata caaaaagctt atcgattagt
     6301 tagaaatggc aaaataataa taatctcagc aacgatcgtc aataatgtta aaacttgttt
     6361 cttcatatta cttccctcct cattagtaat aactttatta taccagggaa ataatcaaat
     6421 ctaccaaaat cgcaaatctg aaatttctat aagaaaaaat atcaaatatg cgattttcta
     6481 aaataagcca atttccgtgt tatactgtcc ttgtaaaaca tttgaagcaa atcctaggtc
     6541 gcagaagtgg tttacaaatg aagataattg aaggagtgta aaagatgtta aatttacaat
     6601 ttgcagaaac aatggaattg acagaagctg agttggagac aggttatgga ggggaatttg
     6661 ggaataatgc tgttatccca gccggtgctt ggggaggttt aggaacgtct tggtcaatca
     6721 ctaatttctg gaagaaatat tttaaccatg attcttccac tgttaatcgt cgccattatt
     6781 gatattcaga gtccttgcct ttttcttggg tagggactgt ctttatttca tagtatagga
     6841 gaaaatagaa tgaaaaagat aatctcacac cgctacttta ttatagtttt tctactagtt
     6901 attgctgacc agaagttcag tgttttagtt ttacgcagcg accttgttgc tgggctatct
     6961 gactttgcct attatctgtc ggatatgatg ttgaattttc ttgtggtttt atttgctctt
     7021 attgctatga tttggtcggg gaaatggcag aaaatcaata gtagaaagtt taaaggatcc
     7081 tatcttttct attccttcct agctctgctt gcttttgttg cttggaattt tgtcaccttt
     7141 tttcttttcc cacctactcg aaatgaaatt tcttatcaac atgctgctcc tacttttaca
     7201 ggagctacgg catttttgat gtattttttt tatcctgtga ttgcaggtcc catttttgaa
     7261 gacatgattt atcgtggatt agtgatgact gctctggaaa aaggaaagaa atgggggcta
     7321 gatgtacttg gttccgctgt tttatttggg gtctcgcaca ttagtaatca cggttgggtc
     7381 ttgacagact ttgtcttcta tatgggtgga ggtcttatat ttgcagtctt atttagaatg
     7441 acaaagtcaa tttattggcc tattggactg catatagtct acaatggcat tggtcagctt
     7501 ttgatgttac tgtaattttg gttgttagta gtatcgcggt ctatccttgg ggaaagattc
     7561 ccatttgaac ttaagaagga gttgtgatga aagtatttct tcaaaataga gattttaggc
     7621 aattaactat caaccagtgg atttcaacgc ttggggatac gattttttat ctggcctttc
     7681 tgaattatgt ggcagatgcg tcttttgcac ctttgacgat tttactcatt acgatttcag
     7741 aaacccttcc ccaaatttta caaatctttc tgggagtttt ggcagatttt caacatcatc
     7801 gtgtcttgaa atacacagtc attagttttg caaaattttt gctttactct atcgtttctt
     7861 tatcactttc agggcagtct ttctccttgt tgctagtagc atttatttgt ctgcttaacc
     7921 tcttgtctga cacattgagt tacttttcag gagccatgct cactccgatt ttcattagaa
     7981 ttattgggca agaccatctg gcagaagcta ttggctttaa acagtcaact gttagtttag
     8041 tgaaaacaat cagtaatatc ctaggaggag tcttactagg cattctatcc atccagttta
     8101 tttccttact gaacgctctt acctttttaa tcgcattttt aggtatcctc ttcataaaaa
     8161 ctgacctctt gaaagtagaa aaaacgatta gctatcaaga aggactctct gtaaaatcct
     8221 tttgccagca tttgctccaa tcatcaaaat tgatatggaa tatgaataag gtgctcttgg
     8281 ttttgtttat tatctctact agtcaagcag tgataaatgt tacggttcct atttccactc
     8341 tatttttaag gaaccagccc tttttgaatt tacaaacagg tcaatctctt gccttgctat
     8401 ccacttttga actgtcagcc ctgattgtcg gaagccttgt aagtggctat ctgcaacata
     8461 ccatttccat aaaaacagct ctctatgcct cacttgtcat ccagttgctt cttctagtag
     8521 gatttgccac agttcgtttt gactggattc tcatctttag taccttggat gcctttttcg
     8581 caggtgttct ctctcctaga ttgcaagaac tcgtttttaa acaaatacct gaggagtcaa
     8641 tgggagcagt tcaatcctct atcggtgcca ttacggttgt tttacctagc ttatttacaa
     8701 tagctttggt aaccattgct actagctttg gaactctggc agttagcttt gttttattgc
     8761 tatttcttct agttgccttt gttatgcttc tgaatattcg tgaaagtatt tagtggagaa
     8821 tttctataat atatgtttga gactggattg ccagtctttt tatgatggtc aaaatcaaca
     8881 gactttttct cttttctgaa tgtgttatag tagactgaat ctaaaatagt acgaaacaat
     8941 tgctaaaaca tttatagaaa ttaattttac tttcccaatc gatttgttct catcttattt
     9001 caatctgcta tataatagtc catgctgtgg ctggattctt ttcagcctac ttgtactctt
     9061 cgaaactctc ttcaaaccac gtcagcttca ctttgccgta gtacggttac tgacttcgtc
     9121 agttctatcc acaacctcaa aacagtgttt tgagctgact tcgtcagttc tatccacaac
     9181 ctcaaaacgg tgttttgagc aacctgcggc tagtttccta gtttgctctt tgattttcat
     9241 tgagtattat taagacaata tgaggagaaa gatgaaagaa aaaggatttt aggagggggc
     9301 gcaggcagcc atgccaacgg ctcttggcta tgtcagtatc ggcctggcct gtggaattat
     9361 cggtgcgccc tatgtgacac ttgttgagat gggcttgatg agtctctttg tttatgctgg
     9421 gagtgcccag tttgccatgt tggcactgat tgtggttcaa gctcctgtgg cagctattgc
     9481 tatgacggtt tttctaatca acttgcgtct ctttttgttg agtttacacg catcgactta
     9541 tttccgtcat accagtcttt ggtacaatat cggtatgtct agtatcttga cagatgagac
     9601 ctatggcgtt ttgatgggtg aattggccca tacagacaag gtaaatccta tgtggatgca
     9661 cgggaacaat ctcaacagct atgtggcttg gtttgtgggg acagtagtcg gaacggctct
     9721 gggtggcctg ctaccaaatc cagaaatctt tggcttggat tttgccctgg ttgggatgtt
     9781 tattggtatt tttgcttcgc aatttcagat tatgcaaaga cggattcctg tccgcaatct
     9841 gctcattatc ctagcagttg ttgcggtgtc cttctttttg ctcttgacag tggtgtctca
     9901 gtcactagct gttctgtttg cgacgctact tggttgtagc atgggggtgg ttttagatgg
     9961 tcagtaagta tcttttatta gcagttattt tctctggtct tgtgacctgg attccccgta
    10021 tgattccctt catcttggtc aagcataagg gcctgcctgc gattgttgag cgttttttga
    10081 agtttttgcc tgtttccatt atctttgcct tgattctttc aagcgtagtg acaggtaagg
    10141 ttgggagcct tcctcaaatt aaatggctag acttcttagc cgtctttcca acagcttggg
    10201 tagcctttcg ctaccgcaat ctagtcggaa cagttctctt tggagtggtc ttgattgcca
    10261 tcttgcgttt ggtcttttaa attacccata aaaaaactta tcacagagat agatatcata
    10321 taatggcgta aatgctcttt ttctgttaag attataaggt attctatttt ggaggaaatg
    10381 acatgaaaaa aatcgttaaa tactcatctc ttgcagccct tgctcttgtt gctgcaggtg
    10441 tgcttgcggc ttgctcaggt ggtgctaaga aagaaggaca agcagctagc aagaaagaaa
    10501 tcatcgttgc aaccaatgga tcaccaaagc catttatcta tgaagaaaat ggcgaattga
    10561 ctggttatga gattgaagtc gttcgcgcta tctttaaaga ttctgacaaa tataatgtca
    10621 agtttgaaaa gacagaatgg tcaggtgtct ttgctggtct tgatgctgac cgttacaata
    10681 tggctgtcaa caatcttagc tacactaaag aacgtgcgga gaaatacctc tatgccgcac
    10741 caattgccca aaatcctaat gtccttgtag tgaagaaaga tgactctagt atcaagtctc
    10801 tcgatgatat cggtggaaaa tcgacggaag tcgttcaagc cactacatca gctaagcagt
    10861 tagaagcata caacgctgaa cacacggaca acccaactat ccttaactat actaaggcag
    10921 atttccaaca aatcatggta cgtttgagcg atggacaatt tgactacaag atttttgata
    10981 aaatcggtgt tgaaacagtg atcaagaacc aaggtttgga caacttgaaa gttatcgaac
    11041 ttccaagcga ccaacaaccg tacgtttacc cacttcttgc tcagggtcaa gatgagttga
    11101 aatcatttgt agacaaacgc attaaagaac tctacaaaga cggaacgctt gaaaaattgt
    11161 ctaaacaatt cttcggagac acttatctac cggcagaagc tgatattaaa taatttcttg
    11221 aaatcatcca ttctgagtaa gatgggtggt ttctcagttt ttagggatat agttttaaac
    11281 tatatatctg actatctaat aacaatttgt gaaatcaaac aaattgtgag atactagtac
    11341 ggtattattt ttaaggagaa agaatcatga aaatcaaaaa atggcttggc ctagcagccc
    11401 ttgctacagt cgcaggtttg gctcttgcag cttgcggaaa ctcagaaaag aaagcagaca
    11461 atgcaacaac tatcaaaatc gcaactgtta accgtagcgg ttctgaagaa aaacgttggg
    11521 acaaaatcca agaattggtt aaaaaagacg gaattacctt ggaatttaca gagttcacag
    11581 actactcaca accaaacaaa gcaactgctg atggcgaagt agatttgaac gctttccaac
    11641 actataactt cttgaacaac tggaacaaag aaaacggaaa agaccttgta gcgattgcag
    11701 atacttacat ctctccaatc cgcctttact caggtttgaa tggaagtgcc aacaagtaca
    11761 ctaaagtaga agacatccca gcaaacggag aaatcgctgt accgaatgac gctacaaacg
    11821 aaagccgtgc gctttacttg cttcaatcag ctggcttgat taaattggat gtttctggaa
    11881 ctgctcttgc aacagttgcc aacatcaaag aaaatccaaa gaacttgaaa atcactgaat
    11941 tggacgctag ccaaacagct cgttcattgt catcagttga cgctgccgtt gtaaacaata
    12001 ccttcgttac agaagcaaaa ttggactaca agaaagcact tttcaaagaa caagctgatg
    12061 aaaactcaaa acaatggtac aacatcattg ttgcgaaaaa agattgggaa acatcaccta
    12121 aggctgatgc tatcaagaaa gtaatcgcag cttaccacac agatgacgtg aaaaaagtta
    12181 tcgaagaatc atcagatggt ttggatcaac cagtttggta ataagaaaca gggaggtggg
    12241 agagaaaatt ccacctcttg cttttgtata gagtatagat tgtaaagaag actattcgtt
    12301 catagaaagg tagagagaat atggtttttc ctagcgaaca agaacagatt gaaaaatttg
    12361 aaaaggatca tgtagtccaa cattattttg aggttttgcg taccttgatt tctaagaaat
    12421 cagtctttgc ccagcaggtt ggactcaagg aagtcgcaaa ttatctgggt gagattttca
    12481 agcgtgttgg agctgaagtg gagattgatg agagctatac agcgcccttt gtcatggcac
    12541 atttcaagag ttcgcgtcca gatgccaaga ccttgatttt ctataaccac tatgacactg
    12601 tgccagcgga tggggatcag gtctggacag aggatccttt tacgctttcg gtccgcaatg
    12661 gcttcatgta tgggcgtggg gttgatgacg acaagggtca tatcacagct cgcttgagtg
    12721 ctttgagaaa atatatgcag caccatgatg atttacctgt caatatcagc tttatcatgg
    12781 agggagcgga ggaatcggct tcaacagacc tagataagta tttggaaaag catgcagaca
    12841 aactccgtgg ggcggatttg ttggtctggg aacaagggac caaaaatgcc ttggaacagc
    12901 tggaaatttc tggtggcaat aaggggattg tgacctttga tgccaaggta aaaagcgctg
    12961 atgtggatat ccactcgagt tatggtggtg ttgtggaatc agctccttgg tatctcctcc
    13021 aagccttaca gtctcttcgt gctgcggatg gccgtatctt ggttgaaggc ttgtacgaag
    13081 aagtacaaga gcccaatgaa cgagaaatgg ccttgctaga aacttatggt caacgaaacc
    13141 cagaggaagt tagtcggatt tatggattgg agttgcctct cttacaggag gagcggatgg
    13201 cctttctaaa acgtttcttt ttcgagccag cgcttaatat cgaaggaatc cagtctggtt
    13261 atcaaggtca gggtgttaag actattttac ctgcagaagc cagtgccaag ctagaggttc
    13321 gtctggttcc gggcctagaa ccgcatgatg ttctggaaaa aattcggaaa cagctagaca
    13381 aaaatggctt tgataaggta gaattatact ataccttggg agagatgagc tatcgaagcg
    13441 atatgagcgc accagccatt ctcaatgtga tcgagttggc caagaaattc tatccacagg
    13501 gcgtttcagt cttgccgacg acagcgggga caggacctat gcatacggtc tttgatgccc
    13561 tagaggtacc aatggttgca ttcggtctag gaaatgccaa tagccgagac cacggtggag
    13621 atgaaaatgt gcgaatcgct gattattaca cccatatcga attagtagag gagctgatta
    13681 gaagctatga gtagagatat tatcaagtta gatcagatcg atgtgacttt tcaccaaaag
    13741 aagagaacca ttacagcggt taaggatgtg accattcaca tccaagaagg ggatatctac
    13801 ggaatcgttg gatattctgg agcaggaaaa tcaacccttg tacgggtgat taatctcttg
    13861 caaaaaccat ctgcagggaa aattaccatt gacgacgatg tgatttttga cggcaaggtg
    13921 accttgacgg cagagcagtt gcgtcgtaaa cgtcaagata tcggaatgat tttccagcat
    13981 tttaacctga tgagccaaaa gacagcagag gagaatgtag cctttgccct taaacactct
    14041 gaactcagca aggaagaaaa gaaggctaaa gtagctaagt tgttggactt ggttggtttg
    14101 gcagatcgtg ctgaaaacta cccttcacaa ctatctggag ggcaaaaaca gcgtgtggca
    14161 attgcgcgtg ccttggccaa tgatccaaaa atcttgattt cagacgagtc aacttctgcc
    14221 cttgatccga agacaaccaa gcagattttg gccttgttgc aagatttgaa ccaaaaatta
    14281 ggcttgactg ttgtcttgat tacgcatgaa atgcagattg tcaaagacat tgccaaccgt
    14341 gtggcggtta tgcaggatgg gcatttgatt gaagagggta gtgtgcttga aatcttctca
    14401 gaccctaaac aacctttgac tcaagacttt atctcaacag ccacaggtat tgacgaagcc
    14461 atggtcaaaa tcgagaagca agaaatcgtg gaacacttgt ctgaaaacag tctcttggtg
    14521 caactcaagt acgctggatc ttcaacagac gagccacttt tgaatgaatt gtacaagcat
    14581 tatcaagtaa tggctaatat tctctatggg aatatcgaaa tcctcgatgg tactcctgtt
    14641 ggagaattgg tggtggtctt gtcaggtgaa aaagcagcgt tggcaggtgc ccaagaagcc
    14701 attcgtcaag caggcgtaca gttaaaagta ttgaagggag gacagtaaga tggaatcatt
    14761 gattcaaacc tatttgccaa atgtctataa gatgggttgg tctggtcagg caggctgggg
    14821 aacagctatc tacctaaccc tctatatgac agttctttcc ttcattatcg gaggcttctt
    14881 ggggctagtg gcaggtctct ttctcgtctt gacagcgcca ggtggtgtct tggagaataa
    14941 agtcgtattc tggattttag acaaaattac ctcaattttt cgtgcgattc cctttatcat
    15001 cctcttggca atcttgtcac cactttctca cttgattgtt aaaacaagta tcgggccaaa
    15061 tgcagccctt gtcccacttt cttttgcagt ctttgccttc tttgcccgtc aggtgcaggt
    15121 tgtcttggct gaattggatg gcggtgtcat tgaggcggct caagcgagcg gagcgacttt
    15181 ctgggacatc gtgggtgttt acctatcaga aggtcttcca gatttgatcc gtgtgacgac
    15241 tgtgaccttg atttcccttg ttggggaaac agctatggcc ggtgcggttg gagctggtgg
    15301 tatcggtaac gtagccatcg cttatggatt taaccgctac aatcacgatg tgaccatctt
    15361 ggcaaccatt attatcattt tgattatctt tgcaatccaa ttcttgggag atttcttgac
    15421 taagaaattg agtcataaat aaaaagagcc gcgtggctct ttttaactga tcagattttc
    15481 tgtgcaaatt ttttactcaa ggcttgtcca atcaaggcac ccactagggc tccgatgaca
    15541 atacttgcga taaatagaag gacagttcca gggtttggag cgaccatgat acggtcgata
    15601 tattcttggg attttcctct tgccagaaga gtagccatat aggctttggg cgcaatccac
    15661 ataagcaaga ttggtcctgt tgtactaaag gcgaaaataa tgaaagaaag gaagttcttt
    15721 gttttgtcct tgtattttcc taaatgagct acttcatctg ctaggaggcc acagataatt
    15781 ccaggaagga aggaaccagc accgtgttta gttcccaaga aaaagagggc aatgacaagg
    15841 ccgatagtgg taatggctcc aaagcgcgga acttttgcga ctaggatcat atagacgcta
    15901 ccgccgacaa gggcagtaaa ggcaggcgca taaaacatgt ttccagtttg gtcaaagaga
    15961 ttgcccaaaa ggacaccaat ccccatgcag aggaagtaaa gaactgcaaa aagcagtgta
    16021 gttaagatag atttcttcat gaattgtctc ctgataattt tttcacaatt ctcattgtac
    16081 cacggtttgg tgggattgta aatggatact agaagttttt gaaaacgctt gaaatatgat
    16141 ataatggttt catagttatt tttaggggaa tatcatgggt agatttttag actttgtctt
    16201 taatcgtttc tttttaggga tgattgcgac agccttcttt tggctattaa ctttagcagg
    16261 agggattatc cttggtctag cgccggctag tgccaccttg atgagcttat atgcagaaca
    16321 tggttatagc tttcgggaat acagtttgaa ggaggcttgg tctctttaca agcaaaattt
    16381 tgtctcaagc aacctgattt tctatagctt tttaggtgtg ggtctagttt tgacctatgg
    16441 tttgtatctc ttggtgcaat tgcctcatca gaccattgtt catttgattg cgaccctttt
    16501 gaatgtccta gtagttgccc tgatcttttt ggcttataca gtatctttaa aattacaagt
    16561 ttattttgcc ttgtcctatc gaaatagtct caaattatcc ttgattggca tctttatgag
    16621 tctagcagct gtggccaaga ttctccttgg gactgtgcta cttgtagcaa ttggttatta
    16681 tatgcctgcc ctgctatttt ttgtaggaat tgggatgtgg catttcttta tcagtgatat
    16741 gttggaacct gtctatgaaa tcatccatga aaaattggcg acaaaataga atgaagcagt
    16801 tttggctaca tacgcttcta agaacctata gttcagtgat gatcattatc attgcgagtt
    16861 ttgcaatctt actctcttac gctgactggg attcacgtga aaaggaagcc cagagagtag
    16921 cccagcgtgt aactgctaga acagtgagtg aaattgaata ttaccataga gagtcaaccc
    16981 agatagctca ggctttagtt gaaaaccaag ctcgtattga gggaatctat aaatacttta
    17041 gtcttagcat gccagactat ttttactggc aattagagcg gaaagcttcg ccttatatat
    17101 cagtctctct gtatgaaaat gttgatgacc tctatgttcg aaatgatttt gtaactggag
    17161 tggccattgc ttttcaagat tacaaggaag tctatgtttc tactaaagac aaacgtagtg
    17221 gagaaaaaat cagggctgag gatttcaaac cagcaggaaa tagttttgcc attccggtgt
    17281 cagatccagt gtcagatcaa gatttaggag tgatttacat ctccttggat cctgctgttt
    17341 tataccatgc cattgataat actagaggtc atactccgat ggcagtaaca gtgacctcac
    17401 cttttgatac ggagattttt catattggtg agacagttga taaggagagt gaaaattggc
    17461 tagttggctt aacttctcat ggatatcagg ttcaggtggc agttcctaaa aactttgttt
    17521 tacaaggaac agtgactagc tctgctttga ttgtgggttt gagccttctc tttattgtca
    17581 ttctttatct gactttgagg cagacttttg ctaattacca aaagcaggta gtggatttag
    17641 tagaatccat tcaagtcatt gctcaaggcg aagaggggcg tcggattgac atttccgaga
    17701 aagatcagga attactccta atcgcggaga cgaccaatga tatgttggat cgattggaaa
    17761 agaatatcca tgatatttac cagttagagc ttagtcaaaa agatgccaat atgcgagcct
    17821 tgcaggcgca aatcaatcct cattttatgt ataatacgct ggagttcttg cgcatgtatg
    17881 cagttatgca gagtcaagat gagttggcag atatcattta tgaattcagt agtctcttgc
    17941 gtaacaatat ttccgacgaa agagagaccc tcctcaaaca ggaattagaa ttttgccgta
    18001 aatacagcta tctctgcatg gttcgctatc ccaagtccat tgcctatggt ttcaagatag
    18061 atccagagtt agagaatatg aagattccca agtttacctt gcaaccgctg gtagaaaact
    18121 atttcgcgca tggtgttgac cacaggcgga cagataatgt gattagcatc aaggctctta
    18181 aacaggatgg ttttgtggaa attttggtgg tcgataatgg tagaggaatg tcggctgaaa
    18241 agttggcaaa tatccgagaa aaattaagtc agagatattt tgaacaccaa gccagctaca
    18301 gtgatcaaag gcagtctatc gggattgtca atgtacacga gcgttttgtg ctctattttg
    18361 gagaccgcta tgccattact atagagtctg cagagcaagc cggtgttcag tatcgtatta
    18421 caattcaaga tgagtagaaa gggagaaaat gtataaagta ttattagtag atgatgagta
    18481 catggtgaca gaaggtctga agcgtttgat tccctttgat aagtgggata tggaggttgt
    18541 cgcaacagcc agtcatgccg atgaagctct agaatatgtt caggaaaatc ctgtcgatgt
    18601 catcatttcc gatgtcaata tgccagacaa aacagggctt gatatgattc gggagatgaa
    18661 agagatctta ccagatgctg cctatatcct gctctcaggt tatcaggagt ttgattatgt
    18721 aaaaagagca atgaacctta gtgtggtgga ctatttggtc aagcctgttg ataaggtaga
    18781 gctgggaaat ctgctggaga agattgcagg tcagctcggc gagagaggga agaaaagtca
    18841 gactcttagt caagaattag acgaggctgg atttgttagt tatttagggg ataaggagaa
    18901 ttggtggata ggtctatcca aggaaaaaca aggttccttc accattccct actatgtctt
    18961 gggtcaagac tggcagattt tcatttctgg ccaaccctta gatggcttag tcgttactcc
    19021 ctttgaagct ccctatcaag aacactttga acgctggaag ctgaatgctg agaaaaccct
    19081 cttttacggt tctgtaaatc tgcagcagtc tgagagtctc tttgcctatt acgaaccgat
    19141 ttatagggtt atcattcagg gaaatctcaa tcaaatcgta gaagagttaa atctcttgga
    19201 gaaggtagtt cttgaaaata cgccgcgtgt tccgattact aaacagcttt ttattcagtt
    19261 tgtcatggat gttttccatt tatttgaaca tctcaaagct gatgacctga cagacatcgt
    19321 taaaaccatt catgctattc aatccttcga tgaattggtt ccttatatca aggaaactct
    19381 gaccagcttt ttcggtcaat accgtatgaa tgaaaatgtg gtcagtgtgc tggaagtcat
    19441 tggtcgtgat taccaaaaag agctttccct caaggatatc agtaaggctc tctttatcaa
    19501 tcctgtctat ctagggcagt tgattaagcg tgaaaccgat tcgacttttg cagagttact
    19561 aaacaaacaa cgtattaagg ctgcccagca gctcttgctt tcaactagtg acagcatcga
    19621 agatatttgt tatgctgttg gttacagtaa ccttggatat ttctataaag ttttccgaaa
    19681 attgtgcgga aaatcgccaa aagcctaccg aaaacaggta gaaactatac tataagattt
    19741 gtattccttt acaaaatgtg ctataatatt atcaggaggt tctatcatga aaaagaaacc
    19801 aatttatcta tgggtcttgc taatcttgtc tgcccttatt tcagttccgt ctctgtttgg
    19861 aattgtgagt cccttgccta gtaaagaagc ccttcgtgct gctcagaaac aagttgcagg
    19921 ggtcaatgct cagcaattag aagaccagct taattatacc tatagagtag cagaagcatc
    19981 tcattctatt tttaatgttg ctttgattgt gctatctact attttagtgg tcgtagcgat
    20041 tgtcttcctt gttcgtaaaa atttgcaata tgcaaactat acttacgttg gctatgtttt
    20101 gttagctatt attggttcga tttatggcta tgttggttta caagatgctg tgcagttggt
    20161 tcaagatgag agcatgcgtt tgacagtgag tattggttca aaagctgtta gcattttcta
    20221 tatcgtcatc aatgttctct tcctagccct tgtcttctat aagatgtggc gacaacagaa
    20281 agccttggca gaagaagagg aaacagaaga gcttgcctaa gtattgacaa aaaagaacta
    20341 tcaagataca atcttggtag ttgttttttg attatagata aaatcatgga ggtacatatg
    20401 aagacaattt ctttagttta tattagtttg agtggcaaca ctgaaagttt tgtgacgcgc
    20461 ttgaaagact atctcttgtc ccagtacaaa gggattgagg ttcaaaagat tcatatcaag
    20521 gatttggtca aggaaggcaa aaatttctac gaaatggacc atccctatgt tgcttttttg
    20581 ccgacctatc tcgaaggtgg gaatggcgtg gataacggag atgttgagat tttgacgaca
    20641 ccggtgggag attttattgc ctatggtaac aatgctagta agtgttttgg tgtggttggg
    20701 tcaggaaatc gtaactttaa taaccaatac tgcctaacag ccaagcaata cagtcaacgc
    20761 tttggctttc ctgtattggc tgactttgaa atgcgaggca tgctggaaga tatcaaacat
    20821 gtcgcagcta ttatcgcaga tttgtatgag ttggaaaagg agaattaata ctcaatgaaa
    20881 atcaaagagc aaactaggaa gctagtcgca ggttgctcaa agcacagctt tgaggttgca
    20941 gatagagctg acgtggtttg aagagattct cgaatagtat aaagttctta taagaggtgg
    21001 ttgaagttgt tcaactgttt tttgagtata aacagtcttt aagaacgtaa aaaagcataa
    21061 gttcaggtct tcaaaacctt gttcttatgc tttttatcat agaaatattt gctgaatttt
    21121 ctcttgaaat gaaaccttat cttcatctcg cgcttgtccc ttaccctgct tttccgattg
    21181 cgagtgcgta gataaagaag atggcgaagc caaagaggaa aatcaatccc gcaatggcaa
    21241 ggtgtttgag ccaagaagga agatttttgt tttcacgtgt taccaaggcg taattcaaaa
    21301 gagcaaagaa aggtgttgtc aggaaagagc caatcatggc aaagcggagc atggttgaaa
    21361 cctgaccagc gaagaacttg ataatgatga taccgatgat agcagtgatg gtcatccaga
    21421 tgttcaaaga tttacgatta tcctcttttt gactgattag cagtcggaga gattcctgat
    21481 taacgcgaga atagccatcg ataacagtta taactgttcc aaagatacag aggaaggcaa
    21541 taaaggtaat caagtaacgg gaccattcgc caagaacaga ggcatacatg cccacgaatt
    21601 gagagatgta tttggctgaa gcagcttcaa ccgcctgccc tgtaggatac tgaatcagtg
    21661 ctcccagtgc cacaaagaag acggctagga tagctgttcc aatataacca gtgttaaagt
    21721 caaacagagc gtcttctgtg ttaaagttga cggtctttct cttttcagct gaccaaagtg
    21781 aattgatggc tgaaatttca ataggagccg gcatccatcc taggagggag acgatgaagg
    21841 gcagagctgc catttgccaa ggtgtcttct cgacaaaatc agaactgtat tctggatgct
    21901 tgaccgccgc aatgataact gcaagaacag tcgcaatggt taaggcagac ataatccatt
    21961 tgaccatgcc gtctaaaagt ttgtagcctc caaagagtag catagcccaa atgattgcaa
    22021 cgagaatgag ggaccactga gtaatgctaa gtccaatcat tgggaaggca ctggcgatga
    22081 tagctgagca cagaatggca acaccagccg tgttgaccat agccgaaaag acattgagga
    22141 taaagaaaat ccagagatag agttttcctt tttcggcata accttcaacc aaagtctttc
    22201 cagtatcagc tgtgtattca gcaccaaaac ggaaaaatgg atatttaaag acattggcta
    22261 agatgaccaa gagaagtaga gaccaaccgt aagaaccgcc agcttgagtt gaggatacaa
    22321 tgtgggaacc tccaacagcg gcagttgcca ttaggattcc aggtcccatt gcttttagct
    22381 tgcttgccca ggttgattga tttaaggaaa tagcttgcga catgataaat actccttttt
    22441 gaattttcag aataatctgt atatgtaatc tatattctac aaaaaatttt ggaaaaatgc
    22501 aagagtattt tgaaaaaaga tagaaaattt acaaagaaaa tctgaaataa ctgttatgat
    22561 atagaggatt gaaactagaa tagtacacct ctgcttctaa aacattgtta gaaatcgatt
    22621 tgactgtcct gatcgattta tcctgttctt atttcatttc actatagtaa ggtgcagcag
    22681 gataaagaaa aaccgagaag tttctttctc ggatttgctt attatgaggt tcctattttc
    22741 tatgctccaa gagttgattg atgtgatcta cttttttagc ctctctttta tagagaatag
    22801 cccagatgat gagatagaca atcgcaaact cgataatgag ctggaggtag aaaatccagt
    22861 ggaaagggaa ccaaccagca agagttgcta gtgggacaaa gccagccagc ataaggaaga
    22921 aatgagtcag agtggcacga agcatgctcc agtcacggct aaataagcgg ttgccaaagt
    22981 tgaagagcat accgatggtt gcccagataa gtgtgcagta gagcaagacc agggcaccgt
    23041 gaacctgatg ctgatccatc acttggccga tgagagagta gggatttagt ggtgcgtagg
    23101 tatttggtgc ataaatgagt gaaaagagga tagagaggat gaggccgata agaacaccgg
    23161 tagctgcatc gtgaaatact tgttttttca tagttctaat ttctccttga tggtttttag
    23221 ataacggcgt gaagagtagg tgaagctttc gtttttcaag aaaatttcta ccagaccgtt
    23281 tggcgtgagc ttgaggtgag agatggaatc gatattgatg atttctgatt gggaaatttg
    23341 gataaaattg gttggcaaga gtttaagaac ctgatagagt cgcaaatcaa tgctgtaggt
    23401 ctgactcgcg gtttctgcta gaaccttccg attctcgata tagaagcgct gaatcttgcc
    23461 aatctcaact agatagacct gatcatcgat ttttcctttg attttttctc tttggtccag
    23521 attttctgcg aactcgatga ctttctggac tttttcggtt tcttgaggtg cttggacaat
    23581 cagcttttcc tcctcgtaag tctcactaat ctgtagttct actttcatag ttttctctcc
    23641 ttttcagtta tacaaggttg tgatcacttc ctgtatatcc ttattaaaca ctattttata
    23701 gcccatggca aggaaccttg tctatgtgga gggattgggc tcctatgtgg tggagctttt
    23761 ctgttctttc tgaaatatgg tataatagca ctaatcaatt tctaggaaaa tagatacgga
    23821 aaggggctga aagaactagg ggaacagttg gaattagaaa gtgataggta tgaaaagtgg
    23881 cgttgaagct gaataagttt ataaagcgtt tgaatgaaga aatggaaagt aaataagttg
    23941 acgatgaatt acaaaataga ttttatctac aatttgtatc tttcaaatca ttgatttgaa
    24001 ttttagattt aatcatgtta caattaaaac tgaaatcaaa tagaagagga aaatgcaaac
    24061 gtgggcacac tattagcaac aagattaaaa aatagacgga aagaattaaa aatgtctcag
    24121 cgagaactag ctgaaggtat ctgtaaacag gggcaaatca gtcgattaga gagcggagag
    24181 tttacccctg gagcggattt cctgaatgcc cttgctaaga agttaaaagt cagtatggat
    24241 tatttttttg atgagcaggt tgtagagaaa gttgaggagt tatcagaatt taagaaatta
    24301 gcacagacat ttattacaaa tcgcaattat gagtctttga aatatatata tgaattggag
    24361 aatgtaaaag ctcaccgcct atctttagca gataaaatct acatggaatg gataaaatct
    24421 ctgatagatt tttattttta cggacagaaa gaagatgcga ttgtacgatt agagggggta
    24481 ttatcacagt taagtgtatc tgatttgaac tatctccaag tttcaaacac cctattcaat
    24541 ttttattatg atattggaga tttaggtcgt ttcaataaaa ttcgtgaaaa actagagtat
    24601 caagtaaatc acctcaattt gagtacaatc gaagagttag aactatctat taagtttaac
    24661 tacaacgttt gtcgttatct atggttacag aaaaatattg aagaagctat tactaaaatt
    24721 acagctacta taaaacaatg taaggcttac agaacgaatt atcttttggc tgatttgtac
    24781 ttattgatgg gaaatgtaag tgaaaatttt tcttctaaaa gttcggtgaa agaatatttt
    24841 gagacggcat attttctata caaacttgag gagaacatgt caatgactct gaaagttgag
    24901 cattacattg cagatataac agaataatga atacggtgtt caagtgagca tcgtttttca
    24961 aacctagttc agatacaaaa aagtatcaaa caaaaaaaaa taaaaaaaca ttataaaaac
    25021 aattgacaag ctaattttga agtgataaaa taaatgcaag aaaacaaaag gagaggtata
    25081 tgagaagttt gtttaagaaa atagttgctg tattagttat tggcttaatt ctgttaggaa
    25141 ttgcgagaac acctcaagtt cataagatgg ctagagggat tgatcctggt cctgcgaatt
    25201 ttatttagaa atcaatttct actaattgag tactaattga gtattaatgg gtaaaaagat
    25261 tgtatggata agaaaaattt acttgtattg gttactggtt cggtaggtgc cagtaatgta
    25321 gatacatact tatattatat aaaaaaattc tataatgtta aagtgatact ttctgaaaat
    25381 tctaaaaaat ttataagtaa ggaattaatt agttattttt gtgataaagt ttatgatgaa
    25441 atatttgttg aagaggtagt tccgcacgtt tttctgccat atgaatctga cttacttctt
    25501 attttaccag ctacggcaaa tgtgattggc aaaattgcta atggtattgc tgatgattta
    25561 gttacagcaa ctgttttaaa ctttaataaa aaaataattt tttgtcccaa tatgaactct
    25621 actatgtggg acaatcacat agttcaaaga aatgtatcaa ttctaaagga gttgggacat
    25681 atatttttat ttgagtctaa aaaaacatat gaggtaggat tgcgtaaagc aatagattca
    25741 acatgttcaa tgttacaacc acagtcgtta gtaaaagaac ttatcaaatt agaaaatatt
    25801 gtccttgaag agggacatta aaaactactg agaatattaa ggaggggaaa aaatggaaaa
    25861 ttcatcaatc gatgtagata tgctgttgga agaattgaca caagaagcaa tggtcgttgt
    25921 tgctgttgat aaggactgtt aatttaaact tatggcaata tatgaaaggt tactggatgt
    25981 tttaaattat gcaggcagta gccttttatt atatacaaat ggataaagta aggataatac
    26041 aatgattaat aaaaaaatac aacaagttgt tttggaatca ttacagaatt ttttgaatgg
    26101 gaacttcatt tcgccttgtg tagtctatga ttttggcttg ctggaaactg tacttgatga
    26161 atttaaaaat caaattcctg taacattcaa ttaccaactt ttttatgccg ttaaagcaaa
    26221 ttcaaatgag aagatacttg aattcttagt agataaaatt gatggagttg atgtggcgtc
    26281 attatctgaa ttagatgtgg ctaaaaaatt tttcccacca actcaaattt ctgttaatgg
    26341 tcccgcattt tcttatgaaa ctttatataa tctgattaaa aaacaatata aagttgatat
    26401 taactttttg gaacatcttc aacaattttc cccaaaagaa tctgttggaa taagagtaac
    26461 ggagccagat gaacttaata atcgtatgag tcgatttgga ataaatattt gcagtgataa
    26521 ttggactagt aatttacaaa atcctttaat tacacgactg cattttcatt ttggagaaaa
    26581 agatgataaa tttattgtta agttagataa aatattattt aagttacaag aaattaataa
    26641 acttagagag gttagagaaa taaatcttgg aggcggtttt atgaaattat ttatggaaaa
    26701 tcgtttgaaa gaattttttc tatcacttat ggaaatctat aaaaagtacg atattgatag
    26761 tactgtgact acaataatag aaccaggtag tgcaattact tcattttctg cctatatgat
    26821 tactagccca gttaatgtta gtgaggtgaa tgagcagcag gttatcacgt tagacacatc
    26881 aatatacacc aatacattat ggtttgttcc gcatattatt acaacgttaa attcaagtag
    26941 taaagagcgt tatagtacta ttctctatgg taatacctgt tatgaacatg acaagtataa
    27001 aatgaaagtt tcgcttccaa ggttaactca aaatagcagt atagtgtttt ttcctgtagg
    27061 agcttatata aaaagcaatc attcaaattt acatcgtaat gattttatgc gggaggtata
    27121 tttgtggaca aaaaacttga catattagat aaagttaagg aatatttagg aaataaaact
    27181 actcaaattc tggataatca atataaagaa tttttgaaac ttaatgatat aaggcgagcg
    27241 tttggtattt cagaaaaagt attaaacaat tcttttaatt ttacgagtaa agaatttaat
    27301 gatttaatta ataacgaaaa ttatttattc gaatatgcat gtagaattag agaggaatgg
    27361 agaaaaaaat gctttaatca ttcttatcgt tttctatgct cacctataat tacagatgat
    27421 tttcttaaca cgaagacatt gagaagtagc caaattgaat ataaatatga gcgatattta
    27481 tcgaaaagtt cgataggcga tagagcggtt gatggctttg tttccttcaa tactttaaca
    27541 gctaatggta tgtctgctat taaactatgt cttgagatat taaactctat tttcttcaag
    27601 aagaagattg atttattata ttcaaccgga tattatgaaa caagattttt attaaataat
    27661 cttgctaaat caggtattag ttgctatgag gtaagtaatt gtgaattgga taaagataaa
    27721 ttttataatg tattcatgat ggaacccaat cgagccgatt taacattaca aaaaactgat
    27781 ttcaagatag tagaatattt tgttaagtat aaaaataatt caataaaagt cgttatttta
    27841 gatatttcat atcaaggttc taattttaaa ttagtagaat ttttagagaa atttaaattt
    27901 gcgaatgtaa ttatttttgt ggtacgatct ttgataaaat tagatcaaat gggattagaa
    27961 ttgacaaatg ggggaataat agaagtgttt attcctaatc atttgagaaa gttgaaaaat
    28021 tttattgaag aggaattcaa taaatttaga aattctcacg gagctaatct aagcctctat
    28081 gaatactgtt tgcttgataa ttctttaact ttaaaaaatg attggaacta ttctgattta
    28141 gttatgaaat ttacgagtaa tttttatgct gatataaaag acttgttcat ggaaaattct
    28201 gatattgaaa tcatccatga agagggagta ccttttgtat ttttagattt aataggtgaa
    28261 ggtaaaaaag aatatgaaat gttttttcaa tggttaaact tcttttacaa acagcttgga
    28321 atcacattgt atgctagaaa tagttttggg tttcggaatc taacagtaga gtattttgga
    28381 attattggga cagaaagata tatatttaag atttgtccag gtgtttataa agggttaagt
    28441 tattatttga tgaaattttt attaaaatct ttttcaaatg aatatttaaa aactactgat
    28501 gaggttaata gatgaaaaat ttgataaagt tgctaataat tagattgatt gttaacttag
    28561 cagacagtgt attttatata gtagcattgt ggcacgttag caataattat tcttcgagca
    28621 tgttcttagg aatatttatt gcagtaaatt atctaccgga tttgttacta atcttttttg
    28681 gaccagttat tgacagagta aatccgcaaa aaattcttat aatatcaatt ttggttcaat
    28741 tagcagtggc tgtaatattt ttattattat taaaccaaat atcattttgg gtgataatga
    28801 gtctagtgtt tatttcagta atggctagct ccataagtta cgtgatagaa gatgtgttga
    28861 ttcctcaagt ggtagaatat gataagattg tatttgcaaa ttctcttttt agtatttcgt
    28921 ataaagtatt agattctatt tttaattcat tcgcatcatt tttacaggtg gcagtaggat
    28981 ttattttatt ggttaagata gatataggca tatttttact tgctctattt atattgttgt
    29041 tgttaaaatt tagaactagc aatgcgaata tagaaaactt ctctttcaaa tattacaaga
    29101 gagaagtgtt gcaaggtaca aagtttattt taaataataa attattattt aaaaccagta
    29161 tttctttaac gcttataaac tttttttatt catttcagac agtagttgta ccgatttttt
    29221 ctattcgata ttttgatggt ccgatttttt atggtatttt tttaactatt gctggtttgg
    29281 gtggtatatt gggaaatatg ctagcgccaa tcgtaataaa atatttaaaa tcgaatcaaa
    29341 ttgttggtgt atttcttttt ttgaacggct caagttggtt agtagcaatt gttataaaag
    29401 actatacttt atcacttatt ttatttttcg tttgttttat gtctaaagga gtcttcaata
    29461 ttatttttaa ttcgttgtac caacaaatac ctccacatca acttcttggt agggtaaata
    29521 ctaccattga ttctattatt tcttttggaa tgccaattgg tagtttagtt gcaggaacgc
    29581 ttattgattt gaatattgaa ttagtgttaa ttgctattag cataccttat tttttgtttt
    29641 cttatatttt ttatacggat aatggattga aagaatttag tatatattag aaatgtttat
    29701 gttcattcaa aagcataatg actataactg aaaaagaaaa gtgatatctt taaggttgtt
    29761 cttcttggtg gtgagattcg tgagacaacc caagcttttg tcggaaagat taccaatgct
    29821 ttgatggata ggatgtactt tagcaagatg tttttagtgg taacggtatc gtggatggac
    29881 gtgtaataac ctcttctttc gaggagtatt ttactaaaaa actagccttg gagcgttccc
    29941 cagaaacgga cttactcatt gactcttcaa agatttgggg agaagatttt gcttcatctg
    30001 ttccttgaaa aaagtcacag cagtcatcac agacgatagt actgaacaaa actatgaaga
    30061 gttagaaatt tatacgcagg tgattgtata aaggatctgg aaatagataa gaagttgatt
    30121 agtattgacc taggtggtac aaatattaag attactgttc tttcaaatga cggtgagatt
    30181 gaaactttgt ggagtattac aacagataca agtgagaaag gttctcaaat tatatcggac
    30241 atcatcagtt ctattaaaaa taaattgacc gaacggaata ttcctgatag cgaccttctt
    30301 ggaatcggta tgggaagttg ctcatcatac tttccttgta aatcataggg gctataaact
    30361 ctccgtctac ttgtcctgca acaattgaag tctgctcaaa acgccgtccg ctaatctttt
    30421 catagacttt ctccctttta ggagcctagc tttctagttt gttctttgat ttttattgag
    30481 tataccacta ttttactccc tctggcaagg gactttgtct atgtggaggg attgggctcc
    30541 tatgtggtgg agcttttctg ttctttctga aatatggtat aatagcacta atcaatttct
    30601 aggaaaatag atacagaaag gggctgaaag atgtctcata ttattgaatt gccagagatg
    30661 ctggcaaacc aaatcgcggc tggagaggtc attgaacgtc ctgccagtgt ggtcaaagag
    30721 ttggtagaaa atgccattga cgcgggctct agtcagatta tcattgagat tgaggaagct
    30781 ggtctcaaga aggttcaaat cacggataac ggtcatggaa ttgcccacga tgaggtggag
    30841 ttggccctgc gtcgccatgc gaccagtaag ataaaaaatc aagcagatct ctttcggatt
    30901 cggacgcttg gttttcgtgg tgaagccttg ccttctattg cgtctgttag tgtcttgact
    30961 ctgttaacgg cggtggatgg tgctagtcat ggaaccaagt tagtcgcgcg tgggggtgaa
    31021 gttgaggaag tcatcccagc gactagtcct gtgggaacca aggtttgtgt ggaggatctc
    31081 tttttcaaca cgcctgcccg tctcaagtat atgaagagcc agcaagcgga gttgtctcat
    31141 atcattgata ttgtcaaccg tctgggcttg gcccatcctg agatttcttt tagcttgatt
    31201 agtgatggca aggaaatgac gcggacagca gggactggtc aactgcgcca agcaatcgca
    31261 ggaatttacg gtttggtcag tgccaagaag atgattgaaa ttgagaactc tgacctagat
    31321 ttcgaaattt caggttttgt gtccttgcct gagttgactc gggctaaccg caattatatc
    31381 agcctcttca tcaatggccg ttatattaag aacttcctgc tcaatcgtgc tattttggat
    31441 ggttttggaa gcaagcttat ggttggacgt tttccactgg ctgtcattca catccatatc
    31501 gacccttatc tagcggatgt caatgtgcat ccaactaagc aagaggtgcg gatttccaag
    31561 gaaaaagaac tgatgactct ggtttcagaa gctattgcaa atagtctcaa ggaacaaacc
    31621 ttgattccag atgccttgga aaatcttgcc aaatcgaccg tgcgcaatcg tgagaaggtg
    31681 gagcaaacta ttctcccact caaagaaaat acgctctact atgagaaaac tgagccgtca
    31741 agacctagtc aaactgaagt agctgattat caggtagaat tgactgatga agggcaggat
    31801 ttgaccctgt ttgccaagga aaccttggac cgattgacca agccagcaaa actgcatttt
    31861 gcagagagaa agcctgctaa ctacgaccag ctagaccatc cagagttaga tcttgctagc
    31921 atcgataagg cttatgacaa actggagcga gaagaagcat ccagcttccc agagttggag
    31981 tttttcggac aaatgcacgg gacttatctc tttgcccaag ggcgagatgg actttacatc
    32041 atagatcagc acgctgctca ggaacgggtc aagtacgagg agtaccgtga aagcattggc
    32101 aatgttgacc agagccagca gcaactccta gtgccctata tctttgaatt tcctgcggat
    32161 gatgccctgc gtctcaagga aagaatgcct ctcttagagg aagtgggcgt ctttctagca
    32221 gagtacggag aaaatcaatt tattctacgt gaacatccta tttggatggc agaagaagag
    32281 attgaatcag gcatctatga gatgtgcgac atgctccttt tgaccaagga agtttctatc
    32341 aagaaatacc gagcagagct ggctatcatg atgtcttgca agcgatctat caaggccaat
    32401 catcgtattg atgatcattc agctagacaa ctcctctatc agctttctca atgtgacaat
    32461 ccctataact gtcctcacgg acgtcctgtt ttggtgcatt ttaccaagtc ggatatggaa
    32521 aagatgttcc gacgtattca ggaaaatcac accagtctcc gtgagttggg gaaatattaa
    32581 aagtataaaa aagtctggga aaaattttca aaatcagaaa aacgcataaa atcaggtgtt
    32641 caaaaacctt gattttatgc gttttatcat agaaatattt acttcatttt ttcctaattc
    32701 ttttcgaaac tctttttaaa cgacgtcagt tttatcagta atctcaaaac agtgttttga
    32761 gctaattttg ccagttttgt ctgtaacatc gaagttgtgt tttaccactc tgcgactggt
    32821 ttcctagttt gctctatgat tttcacagag tattaaattg cgattttgcc aagtttcttt
    32881 attcgtctaa aagtagagtc tgttctatgc gtctaatgta cgaattaggt tgaccatttc
    32941 aatagctcct tgtgcacact cagaaccctt atttcctgct ttagtgccag ctcgttctat
    33001 ggcttgttca attgtatctg tcgttagcac accaaacata acaggaattt cgctatttaa
    33061 actgatttgg gcgattccct tagatacctc gctacataca taatcataat gacttgtatt
    33121 ccctctaatg acagctccca agcagataat tgcatcatat tttttacttt ttgccatttt
    33181 tgatgcaatc agtggtattt caaaagctcc tggaatccag gctaccgcta tatctttctc
    33241 gtttacattc tctcttttga gattatctag tgctccagat aataattttg aagttataaa
    33301 ttcattaaat ctcgctacaa caatacctat tttaatattg tttgctacta aattaccttc
    33361 ataagtgttc atttattttt cctccatatt taaaatgtga cccattcgat ttttctttgt
    33421 ttctaaataa aaactatcgt aaggattggc ttctatttcg attgatattc tactggaaat
    33481 ggtaattcca tatttttcta actgttcaac cttgtcagga ttatttgtca gtaaatgaag
    33541 tgactgaagt cccagatctt taagcatttg tgctccaata tgatattctc ttaaatcacc
    33601 ttcaaagcct aatgcaagat tggcatcaag cgtatccatg ccttgatctt gtaaatgata
    33661 ggcttttaat ttattgataa gtccaattcc tcgtccctcc tgtcgcaagt aaagtaagac
    33721 acccgaacca ttctcaacaa tcattttcat agctttatcg aattgctgtc cacaatcgca
    33781 acgtaaagag cctaaaacat cccctgttaa acattcggag tggacccgac ataatacatt
    33841 ggcttcatcc tctatgtttc ccataataag agcaagatga tgttccccat ttagtttatc
    33901 tatatagcta attgctttga aattaccgta tctagtaggc atattgacag ttgaaactcg
    33961 ttctaccagc tgatcatata cttttctata ttcttgtaat tctttgatgg taattagtgg
    34021 aatgttgtgt ttcttcgaga actgaattaa atcatctgtt ctcatcattt tgccatcatg
    34081 attcattatt tcacaacata ggccacactc ttttagtcca gctaatttta ataaatcaac
    34141 agttgcttct gtgtgtccat ttctttctag aacaccacct ttttttgcaa ttaaaggaaa
    34201 catgtgtcct ggcctgcgaa aatcagaggg tgttatatct tcagctacac acatacgtgc
    34261 ggtcagtcct ctttcctcgg cagaaatacc tgtggtcgtt tctttataat caattgaaac
    34321 tgtaaaagca gtcttatgat tatctgtatt gttttcaacc ataggtgaaa gcattaattg
    34381 attagctaaa ctttcgctca taggcataca aattaatcct ttggcataag tagccataaa
    34441 attaacattt tctgttgtag ctgcttgtgc agaacaaatt aagtctcctt cattttctct
    34501 atccttgtcg tctataacaa gaacaagtcg tcccttctgc aatgcttcta atgcttcttg
    34561 tatttttcga tattccattg actgattatc ctttctgcta aaatccattt tgatataata
    34621 gttccttaga tatttctgat tttggagagt tatccatcag tttttgcaca tatttaccta
    34681 agatatcatt ttcaagattt actgtactcc cgacttgttt actcttaaga atggtttgtt
    34741 ccaaggtatg agggataaca gatactgaaa agtttacttt ggagacttta gcgacagtca
    34801 gactaatgcc gtcaattgta atagatcctt tttcaactat taaatctaaa atttcttttt
    34861 gtgtgttgat ttgataccat acagcattat catctttttt tattgacgag atttttcctg
    34921 taccatcaat gtgtcctgta acgacgtgac ccccaagtcg accgttgaca gataaggctc
    34981 tttctagatt cacctcactt ccatgtttta atagagtaag agctgttcga ctccatgttt
    35041 cattcattac atcaactgta aaggattgat ggttgaaatg agtaactgta agacagatac
    35101 catttactgc tatactatcg cctaaatgga tatccgttaa tatttttgag gctttaattg
    35161 atagtttaca attacgagag tctttctgta ttctttcaac ttttccgatt tcttcaatta
    35221 ttcctgtgaa catggataaa tcacttcact ttctatgaga tagtcatttc ctatttgaga
    35281 aaaagcataa ggtttcaatc taatagcgtc atttggcaaa gaaatgcctt cacctccgac
    35341 aggaaacttg gcactgcctc caaaaatttt tggtgcaata tatattttca gctcatcaac
    35401 aatttgttgt tccaaagcac tccaattcat tagactgccc ccttctagaa ctaggctatc
    35461 aatctgcatg tttcctagat gttgcattaa actcgataag tctatatgat tgcctttttt
    35521 ctttatggaa agtatttcac agccatgatt ttgatatagc ttcattttat ttttgtcttc
    35581 agaggaagtg gcaatgtaag ttttaatatc atttgctgtt tttacgattt tagaggtaag
    35641 aggagttcgt aaatgtgtat cgcatatgat acggatagga tttttccctt cctccaatct
    35701 acatgtcagc aaaggatcgt cttgaataac agtattgact cccaccataa ttgcactaac
    35761 atagtgtcgt aactgatgca catgctttct tgcttcttct tcagtaatcc atttggattg
    35821 atttgtttta gtggctattt ttccatccat tgacattgca tatttcataa aaacataggg
    35881 tacatgctgg gtaatatact ttctaaaact ttttattaag ttaagacact cattttctaa
    35941 aattccaaca gtaacttgaa gattattttc ctcaagtatc tttactcctt ttccagatac
    36001 aataggatta cagtctaggc ttccaatgac tactcttgta ataccactat cgattatagc
    36061 atctatacag ggaggtgttt tcccgaagtg acaacagggt tcaagtgtta cataaagcgt
    36121 cgctccgaca ggggattctc tacagttttt aagagcattt ctctcagcat gtgggccacc
    36181 aaaaaactca tgataacctt gtccgatgat gtgattatct tttacaataa ctgcgccgac
    36241 cataggattg ggattgacgt aaccagcccc tttttgtgcc agttttattg ctaatttcat
    36301 atattttgaa tcgctcatct cactacctcc aaaaaaaata taccttgaat aggggactac
    36361 tcaaggcata caaaagaaaa cttatgcgat taacaaaaat actctgaaat gacaagtaat
    36421 catttcagag cacgcaaaaa gcacaaatat acttttatct tctttcatcc agactatact
    36481 gtcggctttg gaatttcacc aaatcatgcc tttcggctcg tgggctatac caccggtagg
    36541 gaattacacc ctgccctgaa gatagttatt caattacaga tgattatagt acttaatttt
    36601 gaatatgtca acagataaat accgattgtt tttgatatac tgtatttgtg ataatcgatt
    36661 ctcgctcctc ggataaagaa aatatgatat actagataaa cgaaataaga gagaaggaat
    36721 actatgtacg catatttaaa aggaatcatt accaaaatta ctgccaaata cattgttctt
    36781 gaaaccaatg gtattggtta tatcctgcat gtggccaatc cttatgccta ttcaggtcag
    36841 gttaatcagg aggctcagat ttatgtgcat caggttgtgc gtgaggacgc ccatttgctt
    36901 tatggatttc gctcagagga tgagaaaaag ctctttctta gtctgatttc ggtctctggg
    36961 attggtcctg tatcagctct tgctattatc gctgctgatg acaatgctgg cttggttcaa
    37021 gccattgaaa ccaagaacat cacctacttg accaagttcc ctaaaattgg caagaaaaca
    37081 gcccagcaga tggtgctgga cttggaaggc aaggtagtag ttgcaggaga tggccttcct
    37141 gccaaggtcg cagtgcaagc aagtgctgaa aaccaagaat tggaagaagc tatggaagcc
    37201 atgttggctc tgggctacaa ggcaacagag ctcaagaaaa tcaagaaatt ctttgaagga
    37261 acgacagata cagctgagaa ctatatcaag tcggccctta aaatgttggt caaataggag
    37321 cagagaatga caaaacgttg ttcgtgggtc aagatgacca acccgctcta catcgcctat
    37381 catgatgagg agtggggtca gcccctccat gatgaccaag cattgtttga gttgttgtgt
    37441 atggaaacct atcaggcagg cctgtcttgg gaaacggtac tcaacaaacg ccaagctttc
    37501 cgagaagcct ttcatagcta tcaaattcac tcagtcgcag agatgactga cactgaattg
    37561 gaagccatgc tggagaatcc agctatcatt cgaaatagag ccaagatttt tgctacacgc
    37621 gctaacgccc aagcctttct acagttacag gcagagtacg gctcttttga tgcctatctt
    37681 tggtcttttg ttgaggggaa aactgtcgtt aacgatgttc ctgattatcg ccaagcccca
    37741 gctaaaacac ccttatctga gaaattagcc aaagatctca aaaaacgagg cttcaagttc
    37801 acaggcccag tcgccgtatt gtcttttcta caggctgcag ggctagttga tgaccacgag
    37861 aatgattgtg agtggaaagg tcttaaatga tgtctaacaa aaataaggga attctgattt
    37921 ttgcgattct ctatacagtc ctctttgtgt ttgatggcgt taaattgctg gcttctttaa
    37981 tgccatctgc cattgcaact tatcttgttt atgtagtttt agctttatat ggctccttct
    38041 tgttcaagga tagattgatc caacaatgga aggagattag aaagactaaa agaaaattct
    38101 tctttggagt cttaacagga tggctctttc tcattctgat gactgttgtc tttgaatttg
    38161 tatcagagat gttgaagcag tttgtgggac tagatggaca aggtctaaat cagtctaata
    38221 ttcaaagtac ctttcaagaa caaccactac tgatagctgt ttttgcttgt gtcattggac
    38281 ctctggtaga agaattattt ttccgtcagg tcttattgca ttacttgcag gaacggttgc
    38341 caggtttact aagcattatt ctggtaggac ttgtttttgc tctgactcat atgcacagtt
    38401 tggctctatc agagtggatt ggtgcagttg attacttagg tggaggcctt gccttttcta
    38461 ttatttatgt gaaagaaaaa gagaatatct actatcccct acttgttcac atgttaagca
    38521 acagcctctc cttaatcatt ttagctatca gtatagtaaa atgaaataag aacaggacaa
    38581 atcaatcagg acagtcaaat cgatttctaa caatgtttta gaagtagagg tgtactattc
    38641 tagtttcaat acactgtaac atgtgatgaa aatgccagta atgataccga gaaaaaagct
    38701 gagaaacttt tcccagcttt atttgttata gtcaaagcga atgacttgtt cctgtgcatc
    38761 tacatgagca tggaccccaa agggtacaat tgctcttgga gttgcgtggc cgacattcag
    38821 attatagaca atcgggatat tgttgtcaat gatatccaat agtgcctctt tatagtcgtc
    38881 atggaaagtt tcatccatag gttttccgac caagagtcca ttgatgaccg cgaatatgcc
    38941 agtgtccttt aaagttagca acatcttttt gaagtcttct ggcttaggct cttcttcgct
    39001 tgtttcgagc aagaggattt tcccttccca gtctgacaag tcagggaaaa gtttgtattt
    39061 ttggcagagt tccgtgctat ctgcgtatcg agagttgtca aagatatcgt agagggattc
    39121 gaggcaacca ccgaggattt tcccctcgaa ctgagcactt ccttgcaaca agtcaaaacc
    39181 tgtatttgta tgactgacac gaggtgttcc cagggccgtg ggactaaaat cagttcgttc
    39241 ctcataccaa acgtcactag ggcggatttc tgaaattctt cccgtctcaa tcaattcttt
    39301 aaagtagtga aggctatagg ctagcatttc tttgtctaat tcacaaatgt ctgctaaaaa
    39361 ggattgacca taaaaagtct tgattcctaa tttatgcaac atgaggtggt tcatggttgt
    39421 atccgagaag ccaagaaaaa ttttttgttt gataaccttt tggagttggt cattttcaaa
    39481 aagataaggt agcaagcgat aggtatcgtc tccacctatg gcacatagga tcatgtcgat
    39541 gctatcatca gaaaaggcat gaatcaaatc ctctgcacga gcttcaggat ggtccttgat
    39601 aaagtctaat ccttttaacg aatggggcaa aaagatggga ttgagtccca gaaccttgag
    39661 acgttggata cccaagtcca cttcgtgttt gacaaaatcc tctccgataa tgccactaga
    39721 taaactaaca ataccaatag tagaaaccat atctcatcct cctagaaata gattgagcct
    39781 attttatcac aaaatataag agaaagctat gtgggatttc agaagaatac ttttaatact
    39841 cttcgaaaat ctcttcaaac cacgtcagtt ttatctgcaa cctcaaagct gtgctttgag
    39901 caacctgcag ctagcttcct agtttgctct ttgattttca ttgagtataa ctcaaaaaag
    39961 taagtgaaaa agcaaccgca cctgcagttg cttttatcgt tttcttattc ttgatagcgt
    40021 gttggtcctg cacttgcact acggatattc aagcgtttct tgagatagaa gcgaagggct
    40081 aggagagctg ctccaataat agctagtggc aatggatcca gtactgggtt aaggctagct
    40141 ggtaggaagc ttgttgcaaa gaagacaagc aaccaaagga acatagaagc taggataact
    40201 agtacagatt tccagaaagg tggacgttga ctgcgatcca tatctggtcc atagtattgg
    40261 taaacaaagt agtacatcaa gtagaaggca aatccaccaa ccagtccaac taatagaaga
    40321 gtaatcaatc catagccgaa agcttgatct gccgcaaaga aggttgtgag ggcgctgaca
    40381 agggcaaaga ggctagtgat gaaaagagct gagtccataa tcatcagttt tgggtcatca
    40441 ttttcttttg gatgctcttt ttcgtactgc tctttgacag tgaagctatg agcccaatga
    40501 gttggtgcgc cgtataggga acgggcagtt gtacctttag attgctcctc aaggatttgg
    40561 ggaatgactt cctcaaaaat agtctggatt tcagcgtctg ttttcccatc tttgatgaat
    40621 tgttgggtag caatgtggac aaactcttgg tttttcttag ttaatttttg tagatcaatt
    40681 tgagacatag gaactcctct tagaaccatt ttttatggat gagatagaga gtgagcgaga
    40741 cactcatagc aaaggcgata aagacgatta accagaaggc atttggctct ccgtttaggg
    40801 gaatttcatt atccttaaag ttcatcccgt aggcagaaaa gaccatggtt gggatggaca
    40861 tgacgatggt cacaagggcc aaggttttca tgatgttgtt ctggttgtta gaaatgatag
    40921 aggcaaaggt ctctgtcata gaatgcaaga cgtttccata aatatctgcc atctcgatgg
    40981 cctgttgggt ttcaatcagg gtgtcttcaa gcaggtcttc gtcctcaagg tatttcttga
    41041 tattgctggt tgaactggtc aatttcttaa tcacgcgctc atttgttttg agggaggcct
    41101 tgaaatagac gatagttttt tccaattcca tgagctcaat caattcttca ttacgagttg
    41161 attgatgcag ttgactttcg atttgttcac tcttgcggtc gattgaacga agggctgtta
    41221 ggtaaagctc tgcattgcga taaagaattt gaaagataaa acgtgaacgc atgaaggtat
    41281 agaaattacg caatcgacgg ttgataaaga catcaaggac aggtagtggt tccaaacacg
    41341 tagtgataat ggtttcctca gtgatgataa taccaagcgg gatggttacg tagtaggtgc
    41401 ggttatttct ttcctccgtg accggcacgt ctacgataat cagggtatac tcgtcttcaa
    41461 tggtaatacg agacatttct tccgcatcga gcggtgctcg aaggtcggca atatcaatat
    41521 cgaaggtgtt ggcgatttcg agtgattcat tttgagtcgg attgacgaga ttgatccaag
    41581 tacccggttc aagcgtatcg atctctttaa attcagttgt tgtagagaga aaaacttgtt
    41641 tcatatccct tatcctttct catttttcag attttttcac actgtactat tatactacaa
    41701 aatcggcctt ttgggtaata gaatctcact ttttttggta taatggtaag caataatgga
    41761 ctagaaagaa caaagatgca agataaaatt gtcattcatg gggcgcgtgc ccataattta
    41821 aaaaatattg atgtggagat tccgcgagac aagttggttg tcgtgactgg cttgtcaggt
    41881 tcagggaagt ccagtctggc ttttgatact ctctatgcgg agggacaacg tcgctatgta
    41941 gagagtttgt ctgcctacgc tcgtcagttc ttgggaaata tggaaaaacc agatgtagat
    42001 gccattgatg gtctcagccc agctatttcc atcgaccaga aaacgactag taaaaatcct
    42061 cgctcgacgg tgggaacgac gactgaaatc aatgactatc tgcgtctcct ctacgcacgt
    42121 gtggggacgc cttactgtat caacggacat ggagctatca atgcttcttc tgtggagcaa
    42181 atcgttgata aggttttgga gttacctgaa cgccagcgct tgcagatctt ggctcctgtc
    42241 atccgcaaga aaaaaggcca acataagagt gttatcgaga aggttcagaa agacgggtat
    42301 gttcgtgttc gtgtggatgg ggaagtctat gatgtgaccg aagtgccaga gttgtctaag
    42361 agcaagcaac acaatatcga tgtcgtggtt gaccgtattg ttatcaagga gggcattcgt
    42421 agccgtctct ttgattccat tgaagctgcc cttcgtatcg cagaaggtta tgtgattatc
    42481 gacaccatgg acgactctga gttgttgttc tctgagcatt atgcctgtcc agtttgtgga
    42541 tttactgtcc cagagttaga acctcgtctc ttctctttca atgctccctt tggctcttgt
    42601 agtgagtgtg acggcttggg gatcaagctg gaggtagata ctgatttggt agtgccagat
    42661 gccagcaaaa ccttacgtga gggagcgcta gcaccttgga atcctatctc atccaactac
    42721 tatccaaaca tgttagagca ggccatgaaa gtctttggag tggctatgga taagcctttt
    42781 gaggacctgt cagaagaaga taagaacttg attctctatg ggtcagatgg taaggaattc
    42841 catttccact atgagaatga atttggtggc gtgcgcgata tcgacattcc gtttgaggga
    42901 gttatcaata atatcaaacg tcgttaccat gaaaccaata gcgattacac tcgcactcag
    42961 atgcgtctct acatgaatga gctgacctgc ggaacctgtc aaggctatcg tctcaatgac
    43021 caggccttgt ctgtccgtgt gggcggccag caagggccac atattggaga aatctcagac
    43081 ctgtctatcg ctgaccactt ggacttggtg agccagttaa ctttgtctga aaatgaagcc
    43141 atcattgctc gtcccattct caaggaaatc aaggatcgtt tgaccttcct taataatgtg
    43201 ggtcttaact atctaaccct gtcacgttca gcaggaaccc tttcaggtgg ggaaagtcag
    43261 cgcattcgtt tggcaaccca gattggttcc aacctatcag gcgtcctcta tatcctagac
    43321 gagccgtcaa tcggtcttca ccagagggac aatgaccgcc tgattgccag tctgaaaaag
    43381 atgcgtgact tgggcaatac tcttatcgtg gtggaacacg acgaagatac catgcgtgaa
    43441 gctgattatc tgattgacgt tggtcctggt gccggtgttt ttggtggtga gattgttgca
    43501 gcaggtacac ctaagcaagt ggctcgcaac agcaagtcta tcacaggtca gtacttgtca
    43561 ggcaaacgtg tcatcccagt accagaagag cgccgtgtcg gaaatggtcg ttttattgaa
    43621 gtgacaggag cgcgtgagaa caacttgcaa aatgtcacgg ctcgctttcc actaggaaaa
    43681 tttatcgcag tgacaggtgt gtcgggttca gggaaatcga ctctaatcaa cagcattctc
    43741 aaaaaagcca ttgcccagaa gctcaaccgt aattcagaca aacctggtaa gtttaagact
    43801 attacaggga ttgagcatgt cgaccgtttg attgatattg accagagccc tatcggacgg
    43861 acgccgaggt ctaacccagc tacctataca ggagtttttg acgatatacg tgaccttttt
    43921 gctcagacaa atgaagccaa gattcgaggc tacaagaagg ggcgcttcag tttcaacgtc
    43981 aagggaggtc gctgtgaagc ttgctcaggt gacgggatta tcaagattga gatgcacttc
    44041 ttgccagatg tttatgtggc ttgtgaagtt tgccacggaa cccgctataa cagtgaaacc
    44101 ctagaagttc actacaagga aaagaatatt tcgcaggtct tggatatgac ggtcaacgat
    44161 gcggtagaat ttttccaaca cattccgaaa attcaacgca aactccagac catcaaggat
    44221 gtagggctag gctatgtgac cttgggacag ccagctacca ccctttctgg gggagaagcc
    44281 caacgtatga agttagctag cgaactccac aaacgctcga caggaaaatc tttctacatt
    44341 ctggatgagc cgacgacagg gcttcataca gaggacattg ctcgcctgct caaggtttta
    44401 gctcgctttg tagacgatgg caatacagtc ctcgtcatcg agcacaatct ggatgttatc
    44461 aagacggcag accatatcat tgacttggga cctgagggcg gtgtcggtgg tggaaccatc
    44521 atcgtaacag gaactccaga agaagtagct gccaacgaag ccagctatac aggacactat
    44581 ttgaaaggaa agttacatca tgaataaacg cgtacaagca tttctagcta aaatgcaaga
    44641 aaaagaacta gatggtatca tcatcaacaa tcttaaaaac gtctattatt tgactggttt
    44701 ttggggctca aacggaacag tctttatcag tcgtgaccgt caggtcttag tgacagactc
    44761 tcgctatatc atcgcagcta agcaagaaac cagtggtttt gagattgtgg ctgatcgtga
    44821 tgaattggct gtcattgcag gaattgttaa ggacatgggc ttgactcgta tcggttttga
    44881 agatgagatt tcagtgtctt attaccaccg tatgcaggca gcttttgcag gtttggactt
    44941 gtttccgcaa actcagtttg tggaaggtct tcgtatgatt aaggatgagg cagagattgc
    45001 agcgattcgc aaggcttgtt ctatctcaga ccaagctttc cgcgatgcgc ttgactttat
    45061 caaaccagga aaaactgaaa ttgagattgc caacttcctt gacttccgca tgcgtgagtt
    45121 gggagcatct ggcttatctt ttgatacgat cctagctagc ggtatcaatt cttctaaacc
    45181 ccatgcccat ccaatgcaca aaccagtgga gttgggagaa gccattacca tggacttcgg
    45241 ctgtctctat gaccactatg tcagtgatat gacccggact atctatctag ggcatgttag
    45301 cgatgagcag gcagagattt acaatacggt tctaaaagct aaccaagcct tgattgacca
    45361 agctaaggca ggcttaggtt tccgtgactt tgacaaaatc cctcgtgata ttatcattga
    45421 ggcaggttat ggcgactact ttactcacgg cattggccac ggtattggtc tggatatcca
    45481 tgaggaaccc tactttagcc agacttctac agaaactatt aagacaggta tggccttgac
    45541 cgatgaacca ggtatctata tcgaaggcaa atatggcgtt cgtatcgagg atgatatcct
    45601 gattacagag acaggttgtg aattattgac cctagctcca aaagagttga tagtcattta
    45661 gttgtttgtc aagaaaaaag tacgaaaatg acgaaaaaag tcaaaaaaaa ttaaaaatag
    45721 gtcgcaagtc ggatgttttt tatggtataa tagactaaac tgatagtaac atgtagcgaa
    45781 aggggtaggt acatgattaa aatttataca gtctcaagtt gtactagctg taaaaaagca
    45841 aaaacctggc tcaatgccca ccagttaagt tataaagaac aaaaccttgg taaagaagga
    45901 attacgagag aagaattact ggatattcta accaaaacag ataacggaat agccagcatc
    45961 gtttcgtcta aaaatcgcta tgccaaagcc cttggagtgg atattgaaga tttgagtgtc
    46021 aatgaagttc tcaatctgat tatggaaaca ccgagaattt taaagagccc aatccttgta
    46081 gatgaaaaac gcctgcaagt tggctacaag gaagacgata ttcgtgcctt cctaccacgc
    46141 tctgtccgta atgtagaaaa tgcagaagca cgtttacgtg cagctctata aacatcaagg
    46201 ctgggagcaa ttcccagtct tattctattt taatttcaaa aagaaagaag aaagaaatga
    46261 aaaaaatagt tcttgttagt ctagctttcc tttttgtcct ggttggttgc ggacagaaaa
    46321 aagaaactgg accagctaca aaaacagaaa aggatacgct tcagtcggca ttgccagtta
    46381 ttgaaaatgc cgagaagaat acagttgtaa ccaagacttt ggtcttgccc aagtcagatg
    46441 atggtagcca gcaaactcaa accattacat acaaggacaa gacttttttg agcttaacga
    46501 ttcaacaaaa acgtccagtt tctgatgagt tgaagactta tattgaccaa catggagtgg
    46561 aagaaactca aaaagctctt cttgaagcgg aggagaagga taagtctatc attgaagctc
    46621 gtaaattggt aggtttcaaa cttgaaacaa aactattgag cgcaacggaa cttcaaacaa
    46681 cgactagttt tgattttcaa gttctggatg tcaagaaggc ttcccagttg gaacatctga
    46741 agaatattgg tttggaaaat cttttgaaaa atgaaccaag caaatatatt tcagacagat
    46801 tggcaaatgg tgcgacagaa cagtagaaaa tccaaataaa tagactgcct gaattgtaga
    46861 aggtaaggaa ttatgctata atggtactat tctaaggaaa gagggtgtta gaatgggatt
    46921 tactgaagaa acagtacgtt ttaaattgga cgattccaat aaaaaagaaa ttagcgaaac
    46981 tttgacagat gtttatgctt cgttgaacga taagggttac aacccaatta accaaatcgt
    47041 aggttacgta ttgagtggag accctgccta cgttcctcgt tataataatg cacgaaatca
    47101 aatccgtaag tatgagcgtg atgaaatcgt tgaggaattg gttcgctact acctcaaagg
    47161 acaaggagtc gatctataac ctatgagaat tatgggattg gacgtcggtt caaaaacggt
    47221 aggggtggcg attagcgatc cgcttggttt tacagctcaa gggcttgaaa tcatccagat
    47281 aaatgaagaa caaggccaat ttggttttga ccgcgttaag gaattggttg atacttacaa
    47341 ggtggaacga tttgtagtgg gcttgcctaa aaacatgaac aatacaagtg gaccgcgcgt
    47401 agaagctagt caagcctacg gagcaaagct agaagagttt tttggtttac cagtagacta
    47461 tcaggatgaa cgcttgacaa cagtggctgc tgagcgcatg ttgattgaac aagcagatat
    47521 cagtcgcaat aagcgcaaga aagtcattga taagttagca gctcagctga ttttacaaaa
    47581 ttatttagat agaaaatttt aatataaagg agaggctatg tcacacgatc ataaccacga
    47641 ccacgaagaa cgtgaactaa tcacactagt agatgagcaa ggaaatgaaa ccttgtttga
    47701 aatccttttg acaattgatg gaaaagaaga atttggtaaa aactatgttc ttctagtacc
    47761 agttaacgca gaagaagacg aagacggaca agttgaaatc caagcttact cattcatcga
    47821 aaacgaagat ggaacagaag gcgaattgca accaatccca gaagactcag aagacgaatg
    47881 gaacatgatt gaagaagtct tcaacagctt tatggaggag tgatacagtc tgggagactg
    47941 tatcagccca actcccagaa atggggaaga gttggaacgt ccagtggatg tttttagccc
    48001 agttccttta aataagagag aactggtagg ttcgggggga cgtttttagc ccagctcctt
    48061 taaataagat agagctggta agtctgggag actgtatcag cccaactccc agaaatgggg
    48121 aagagttgga acgtccagtg aacattttta ccccaactct tagaaattga gaagagttgg
    48181 aacatctagt ggatgttttt agcccatatt cacattcata gtggctagtt attagctaac
    48241 caggtaagag gtcgggacga aaatcctggc cttgttttta ttagtaacca tactttaatg
    48301 cgataattga ttggactttt gtcaaggaga tgtgtatgtt tgaagtagaa gaatggctcc
    48361 atagtcggat tggtttaaat tttcgatcag gtttgggccg aatgcagcaa gcggtggatt
    48421 tgttaggaaa tcctgagcag tcttacccta ttatccacgt aacagggact aatgggaaag
    48481 gatctaccat tgcttttatg agggaattat ttatggggca tggcaaaaaa gttgcgacct
    48541 ttacctcccc tcatatcgtc tctatcaatg accgaatctg cattaatggg caacctatag
    48601 cagacgcaga ctttatccgt ttggctgatc aggtcaagga gatggagaaa acgcttctgc
    48661 aaactcctga ccagttgtcc ttttttgaat tgctgacctt ggttgctttt ctttatttta
    48721 gggagcaaga ggtggatttg gttttattag aagtgggaat tggtggctta cttgacacga
    48781 ccaatgtggt aactggagag cttgctgtca tcacctccat tgggcttgac catcaagaaa
    48841 ccttgggtga tagtctagaa gcaattgcag agcagaaagc tggtattttc aaggctggta
    48901 agaaggcagt gattgcgaaa ttgcctccag aagctaggct tgtctgtcag aaaaaagccg
    48961 aatctttagc tgttaacctt tatcaggcag gtcaagattt tttaatgctg aatggtgatt
    49021 tttcaagctc tttactaaat ctttcacagc tgaacatagg cttagaagga gtctatcagc
    49081 aggagaatgc agccttggcg ttgcaaactt ttcttctttt tatgggagaa ggaaaggaag
    49141 ctgttgatga acaggctgta agaaaggcct tggaacagac ccattgggct ggtcgcttgg
    49201 agcgtattcg cccacagatt tacttggatg gtgctcataa cctccctgcc ttgactcgct
    49261 tggttgagtt tatcaaagaa aaagagcagg aaggctatcg acctcaaatc ctttttggag
    49321 ccttgaaacg gaaggattat caagggatgt taggttacct gactgaaaaa ttgcctcagg
    49381 tggaactcaa ggtgaccggc tttgactatc agggggcttt ggacgaaagg gatgtgacag
    49441 gttacgatat agtttcttct tgccgagaat ttatcagcga ttttgaagaa agagcagatg
    49501 ctcaggattt gctgttcgtt acagggtctc tctattttat ctcagaagta cggggctacc
    49561 tgctggaccg tgagcagata aattgacccc cttgtttgaa cttgttatac taggggaatt
    49621 gctggttaga gaaaatttct ctaaattggt agcagaaagg aaattcatca tgaaattaaa
    49681 aagattcaca ctttctcttg cttctctagc aagttttagt ctcttagtag cttgttcaca
    49741 aagagctcaa caggttcaac agcctgttgc tcagcagcag gtccaacagc ctgctcaaca
    49801 acctgctcaa cagaatacca atactgcaaa tgcaggaggt aaccaaaatc aagcggctcc
    49861 agtacaaaac caacctgttg ctcaaccgac cgatattgat gggacttata ctggtcagga
    49921 tgacggagac cgtatcactt tagtggtaac tggaacgact ggtacatgga ctgagctcga
    49981 atctgacggg gatcagaaag tcaaacaggt tacatttgat tcagcaaatc aacgcatgat
    50041 tattggcgat gatgtcaaaa tttacactgt aaacggtaat caaatcgtcg tagatgatat
    50101 ggatagagac ccatcggacc aaatcgtttt aactaaataa gactatgcaa gtagaaaggg
    50161 ctggattttt cagccttttt acttttacct agaaaataat cataaatact tgccttctac
    50221 cgaatacctg cgttatacta gtatcaatta cttgttttta gcattcaaac tatcaaggag
    50281 gggatatgaa atataggaaa tttcaattat tgatgtccaa gtatggcttt agtctttcga
    50341 ttatgttact tgaactttgt cttgtttttg gtctctttct ttatttagga cgcatggctc
    50401 ccattttatg gattactgtc ctcattctac tgagtatcat cacaatcatt tcgatagtca
    50461 accgtaatac gactcctgag aataaggtaa cctggttgtt agtagccttt gtgccagtat
    50521 ttggtccctt gctctatctg atgtttggtg aaaggcgatt gtccaaaaaa gaaatcaaac
    50581 aactgaagaa gctaggctct atgcatttcc aagaagcaaa tagccagcta ctaaaagaga
    50641 aattaaaaga aagtgacaag gcagcttatg gagtcatcaa gtccttattg agtatggata
    50701 ccaatgctga catctatgat caaactgcct ctacattttt tcctaacgga gaagctatgt
    50761 ggaaaaagat ggtagaagat cttaaaaagg ctgagaaatt tattttcttg gaatattaca
    50821 ttatagaaga aggtttgatg tggaatcgca tactagatat actagagcaa aaggtagctc
    50881 agggtgtaga ggttaagatg ctctatgatg atatcggctg tatggctact ttaacaggag
    50941 attatgcaca tcgacttcgt cagctgggca tcgaggccca taaattcaat aaagttattc
    51001 ctcgtttgac agtggcttat aataacagag atcatagaaa aatattgatt gttgatggtc
    51061 agatagccta tactggtggg atcaatctgg cagatgagta cattaaccac gtcgagagat
    51121 ttggttattg gaaggatagt ggaattcgct tagacggact agcagtaaaa gctctgacac
    51181 gcttattttt gaccacttgg tacattaatc gaggagaaat tagtgatttt gatcaatatc
    51241 atttagaaaa tcattctatc ccgagtgacg gtttaaccat tccatacgga agtggaccca
    51301 agccaatttt tcgagcgcag gtagggaaaa aagtttatca gagtttaatc aatcaagcaa
    51361 cagaatcggt ctatattacg acaccttatt tgattataga ttatgattta acagagacaa
    51421 tcaaaaatgc agctatgaga ggggtcgatg ttcgaattat caccccttac ataccagata
    51481 agaagttcat tcagttagtc acgagaggag cttatcccga ccttctttct gctggtgttc
    51541 ggatttatga gtatagtcca ggttttattc atagtaagca gatgttggta gacgaagatt
    51601 ttgcggtggt ggggacaatc aatctcgact accggagctt ggtacaccat tatgaaaatg
    51661 cagtcttact ctataaaact ccttctataa gggaaatcgc ccgagatttt cgaaatatat
    51721 ttgcagattc tcaggaagtc tatcctcatt ctatcaaaac gagctggtat caaaagcttg
    51781 taaaagaaat cgcccagcta ttcgccccta tcttataaga aatctagaac ttaggataca
    51841 aaccagacct atttttcttg tcttttacga atagaaagaa agaggagggg aattcatgct
    51901 aactaaggaa gaagtgaatg atatgattga gttcaaacag acacatttac accgctttcg
    51961 ggaaattgaa acctttgtga aactatgcaa aaaatcactc aaacagccat cgcaagctga
    52021 caatcctagg actttttgat atactaagac agataaattg aacaggagaa acgatatgag
    52081 tgtgtatggt agagtagaag aagttcataa ggagaatcgt gaacctctag aataccaaat
    52141 cgaacaagaa tcgcatcatc gtgaatcaag tcgtcttcct ttggtgaaaa ttttactatg
    52201 gagtacgctt gtaacgggga taactctagg agtaccgcta ttactcgact taatgagtgc
    52261 acaagaagtg caggattttt atgcaggttg ggcgcttcat cagacaggga agatttacag
    52321 cgactattat ggaagtcaag gtttgcttta ttatttgctg acttacgtga gtcagggcgg
    52381 atttttcttt gccatctttg agtggttagc cttggtagca ggaggatttt tcctttttag
    52441 atcagcggac accttgacag agcaaggaga ccaagctgga catctggtga ctatttttta
    52501 catgctagtt acaggtcttg cttttggtgg aggctatgcg actcttttag cgcttccttt
    52561 cttattcgca gcctttagtt tagttgcggc ttacctaagc aatccaagcc atgataaggg
    52621 atttgtacgg attgggctag ctttggcagg cggatttttc tttgctccct tatcatcgct
    52681 cctgtttatt gctgtagtga gtttaggctt gttggtcttt aaccttgggc atagacgctt
    52741 tgcgcatggg ttttatcagt ttcttgcagt ggctttaggt ttttcacttg tcttttatcc
    52801 aactgcctac tatagtgctg caacaggaag ttttggggat gcgattagtg gtattcgtta
    52861 tcctattgac agtattcgct ttgattttac ttctaaaatt ttagagaata tgttttttta
    52921 tggcttgttg tcccttggtt tgggatttgt ggtttgtatc tttttaggtc tctttcaatc
    52981 caaacccttt aaactatacg tcatttcggt tcctgcaagt cttgtggtaa ttttaggttt
    53041 gattttactt ttcttttcac aagagcctct gcacgcttct tatttgatgg tcgtcttccc
    53101 tgttttccta cttttattgg taaccaatat taagagtcaa cagagggggc gtagtgctag
    53161 aagaagccga agagaaacgc cagttagcct atggagtcgt ttcttcaaag gaaatctata
    53221 tctgctagtt tttgagtttg tctatctttt gtctgttcct tttttgatga agtttgtcct
    53281 ttatccagta ccttatcaag aacgtaatcg tcttgctgat ttggtaaaag aggagacaaa
    53341 tacggaagat gctatctatg catgggatga tactgcgact ctttatcgta agagtgagcg
    53401 cttgtcgcca tcggcgattt tgtccccgtt gcactataca gcaactgagg aaaatcgtaa
    53461 taagttactt aatgacttga aagaaaaaca acctaaggtg attgtggtaa atgataaggt
    53521 ggtagtctgg tctgaagtgg aaacactctt aaaagaaaat taccaacaag taaagactga
    53581 ttactcagag tttaaagtct ataaaattaa ataaccaaat caatatcttg tgtattttta
    53641 aaaattttag gatttttaac acaagatatt gatttttctt tttagagtgg tataatactt
    53701 tttagaaaga acattttaga aaagagcatg catatgattg cactagaaga aaaaattaca
    53761 attttgccaa ctctcttcgt cgagaaacga gatgggagac gtgttgtatt tgatgtggac
    53821 aagattgaca aggctctcca caaggcggct gacaaggtta tggatgtgac acccctggtt
    53881 gaaaaacgcc tcaatgatct gactgagcga attattacag aaattcatag tcgctttcca
    53941 cagggaatta agatttacga aattcaaaat atcgtagaac atgaactcct tgaagccaaa
    54001 gaatatgcgc tggctgagga gtatattact tatcggacac agagggattt tgagcgctca
    54061 aaagcgacgg atatcaactt tagtattcat aaacttctca acaaagacca gacagttgtc
    54121 aatgaaaacg ctaataaaga cagtgatgtc tttaacactc agcgtgattt gacagcaggg
    54181 attgttggga aatcaatcgg actgcaaatg cttcctaagc acgtagccaa tgcccaccaa
    54241 aagggggata tccactatca cgatttggac tacagtccct atacccctat gaccaactgc
    54301 tgtttgattg attttaaggg tatgttggaa aatggtttta agattggaaa tgcagaggta
    54361 gagagtccca agtctatcca gactgcgaca gcacagattt ctcaaatcat tgccaacgtt
    54421 gcttctagcc agtacggtgg ctgttcagct gaccgtatcg atgaaatttt ggcgccttat
    54481 gcagagaaga attatcaaaa acatctcaaa gatgcagaag agtgggtatt gcctgaaaaa
    54541 cgggaagatt acgcttggaa gaaaacgcaa aaggacatct acgatgccat gcaatctctt
    54601 gagtatgaaa tcaatactct cttcacttca aatggacaaa caccttttac ttcgttaggt
    54661 tttggtctgg gaaccagtcg ttttgaacga gaaattcaaa aagctatttt aaacattcgc
    54721 atcaagggtc ttggttcaga acaccgtacg gctatctttc ctaaacttat tttcactctg
    54781 aaaagaggcc ttaatttaga ggaaggaact cccaactacg acatcaagca gttggctctt
    54841 gagtgtgcaa ccaaacggat gtatccagat gttttatctt acgataagat tgttgacttg
    54901 acaggatcct tcaaggtgcc tatgggttgc cgttctttcc tccaaggatg gaaggatgaa
    54961 aatggtgtag aagtcaattc aggtcgcatg aatctgggtg ttgtgacggt taatctgcct
    55021 cgtattgctc ttgagtctga aggtgatatg aataagttct gggaaatctt caacgagcga
    55081 atgaatatcg cagaagatgc tcttgtttac cgtgtcgaac gcactaaaga ggcgacacca
    55141 gcaaatgctc ctattcttta tcagtacggt gcttttggcc atcgtctagg taaagaagaa
    55201 agtgttgacc agctctttaa gaatcgtcgt gctaccgttt cgctgggcta tatcggcttg
    55261 tatgaagtag cgacagtttt ctttggtaac agctgggaaa gtaatccaga tgctaaggaa
    55321 ttcacgctag acatcattca cgatatgaaa cgccgtgtag aagagtggtc agaccaatat
    55381 ggctaccatt tctctatcta ctcaacacca tccgaaagtc tgacagaccg tttctgccga
    55441 ctagatatag acaagtttgg ctctattcct gatatcacag acaaggaata ctacaccaac
    55501 tctttccact acgatgttcg taaaaatcca acaccgtttg aaaaattgga ctttgagaaa
    55561 gtctatccag aagcaggtgc gtcaggtggt ttcatccatt attgtgagta tccagtcctt
    55621 cagcaaaatc caaaggcctt ggaagctgtc tgggattatg cttatgaccg tgtaggctat
    55681 ctaggcacca atactccgat tgaccgttgc tacaagtgtg actttgaagg ggattttgaa
    55741 ccaactgaga gagggtttgc ttgtccaaac tgtggcaata gcgaccctaa aacagtagat
    55801 gtggtgaagc gaacttgtgg ctacctaggt aatcctcaag caagaccgat ggtcaacggg
    55861 cgtcacaagg aaatcgctgc gcgtgtcaaa catatgaatg gttcaacgat taaaatagct
    55921 gggcatcaag taacaaatta gaaagaaatg aaatgggaaa atatcaacta gacgataagg
    55981 ggcgcgcaca agtgacccgt tatcacgaga aacactctaa aggtggagct ggtaagaaag
    56041 aacgcttgct tagcttcaga gaacaatttt taaacaagaa caagaaaaaa taaaagtgag
    56101 agccagctct cgcttttctc atagtgggag gtaaggatgg aattacgcag accaagatta
    56161 gcggataaga aagctgtttt agatatgatg acagagtttg aaaagagtca atcagcccat
    56221 gatggaggat tttgggatgt tgaggatttt tcttacgagg agtggctaga aggtaaccgt
    56281 aataaagaaa tgggaatatg gctacctgaa aatcgcgttc catcgataca gttcgtattg
    56341 tttggtgaat caggttgtgc tctaggattt ttgaatctgc gattgagact gaatgagggg
    56401 ttactgaatt atgctggcca cattggctac tccatccgtc catctgaaag aggcaagggt
    56461 tatgcaaaag agactctccg tcagggcttg caagttgcta aggaaaagaa catcaagaaa
    56521 gctctggtga cctgtagcgt gaataatctt gctagcagag cagtcattct agcaaatggt
    56581 ggaatatttg aggatgctcg caatggagtc gagcgttatt ggatagaggt agcgaatgaa
    56641 taatccaaaa ccacaagaat ggaaaagcga ggaacttagt caaggtcgta tcattgacta
    56701 caaggccttt aactttgtgg acggcgaagg cgtgcgtaac tctctctatg tatcaggctg
    56761 tatgtttcac tgcgagggat gttataatgt tgcgacttgg tcttttaatg ctggcattcc
    56821 ctatacagca gaattagaag agcagatcat ggcagatctt gctcagccct atgttcaagg
    56881 tttgactttg ttgggagggg agccttttct taatactggg attctcttgc cacttgttaa
    56941 gcggattcgg aaggaattgc cagacaagga catctggtcc tggaccggct acacttggga
    57001 agaaatgatg ttggaaactc cagataaact ggaattcttg tcactgattg acattcttgt
    57061 cgatggaaga tatgatcgaa ctaagagaaa tcttatgctc cagtttcgag gttcgtctaa
    57121 ccaacgaatt atcgatgtgc aaaaatcgct caaaagtggg caagtagtga tttgggacaa
    57181 gctcaatgac ggaaaagaaa gctatgaaca ggtgaagaga gaatgaagaa aaaagactta
    57241 gtagaccaac tagtctcaga gatcgagacg gggaaagtca ggacactggg aatatacggt
    57301 catggagctt caggtaaatc aacctttgca caggaattgt accaagcttt agattctact
    57361 acagtaaatt tgctagagac agatccttat atcacctcag gacgccatct ggtagtaccc
    57421 aaggacgcgc cgaatcaaaa ggtgacagcc agtctgccag tggcgcatga actggagagt
    57481 ttgcagagag atatccttgc cttgcaggcg agtatggatg tcttgacaat tgaagaacct
    57541 tggaaggcta gtgaggtctt gtctggagcc aaaccaattt tgattgtcga agggatgtct
    57601 gttggctttc tacccaagga actctttgaa aaaaccatct gtttctacac ggatgaggag
    57661 accgaattaa agcgacgcct tgctagagat acgactgtga gaaatcgcga tgcatccttt
    57721 atattggcta gccatcagat gagacgggag cagtatctgc gatactataa agaaactgag
    57781 tctaaggcgg atatcttagt ggaccaatca gaagataaat ttgatgtcaa gaggacttaa
    57841 cttatgtata gaagaaatat agaagaaaat ccctaatttt agaaagaaaa agtaggaaaa
    57901 cagtttcatc cccaaaaaac gaaaaaacct aacaaatccc ttgcaatcgc aggggatttg
    57961 tgttattcta ttatggtgct gtaaattaca gccttagttt tgatgcaaga ggttgcgaca
    58021 cgctcggttg cattgccacg caacaccgcg tcggttttct tgtggagcta gcctattatc
    58081 ttaaatagac gaaaaggaga aaaagatggc aaacaaaaaa atccgtatcc gtttgaaagc
    58141 ttacgaacac cgtacgcttg acacagcggc tgcaaaaatc gtagaatcag ctactcgtac
    58201 aggtgcacaa gttgcgggtc caatcccact tccaactgaa cgtagcctct acacaatcat
    58261 tcgtgcgact cacaaataca aagactctcg cgaacaattt gaaatgcgta cacacaaacg
    58321 tttgatcgat atcgttaacc caactcaaaa aacagttgat gccttgatga aattggatct
    58381 tccaagtggt gtaaacgtag aaatcaaact ttaatctaaa atataaaaga gcagaggctg
    58441 gtgtttcaat ctaattgaac acgggctaaa ctcggtgtga aaaagataaa cttcctcgcg
    58501 tctgctagac actgtgtcag tttcctattt tcactttgag tttgacgccc tttgtatctt
    58561 agacttgagc ataaaaaacg ctcgttaaaa actttttgaa taaaaaatat agaaaaggaa
    58621 ctattttctc atgacaaaag gaatcttagg gaaaaaagtg ggaatgactc aaatcttcac
    58681 tgaagctggc gaattgatcc ctgtaacagt tattgaagca actccaaacg ttgttcttca
    58741 agttaaaact gttgaaacag acggatacaa cgctatccaa gttggtttcg atgacaaacg
    58801 cgaagtattg agcaacaaac ctgctaaagg acatgtagcg aaagctaaca cggctcctaa
    58861 gcgcttcatt cgtgaattca aaaacgttga aggcttggaa gttggtgctg aaattacagt
    58921 tgaaacattc gcagctggag acgttgttga cgtaactggt acttctaaag gtaaaggttt
    58981 ccaaggtgtt atcaaacgcc acggacaatc acgtggacca atggctcacg gttctcgtta
    59041 ccaccgtcgt ccaggttcta tgggacctgt tgcacctaac cgcgtattca aaggtaaaaa
    59101 ccttgcagga cgtatgggtg gtgaccgcgt aacaattcaa aatcttgaag ttgtacaagt
    59161 tgttccagaa aagaacgtta tccttatcaa aggtaacgta ccaggtgcta agaaatctct
    59221 tatcactatc aaatcagcag ttaaagctgg taaataataa agaaagggga aatcagtcac
    59281 aatggcaaac gtaacattat ttgaccaaac tggtaaagaa gctggccaag ttgttcttag
    59341 cgatgcagta tttggtatcg aaccaaatga atcagttgtg tttgatgtaa tcatcagcca
    59401 acgcgcaagc cttcgtcaag gaacacacgc tgttaaaaac cgctctgcag tatcaggtgg
    59461 tggacgcaaa ccatggcgtc aaaaaggaac tggacgtgct cgtcaaggtt ctatccgctc
    59521 accacaatgg cgtggtggtg gtgttgtctt cggaccaact ccacgttcat acggctacaa
    59581 acttccacaa aaagttcgtc gcctagctct taaatcagtt tactctgaaa aagttgctga
    59641 aaacaaattc gtagctgtag acgctctttc atttacagct ccaaaaactg ctgaatttgc
    59701 aaaagttctt gcagcattga gcatcgattc taaagttctt gttatccttg aagaaggaaa
    59761 tgaattcgca gctctttcag ctcgtaacct tccaaacgtg aaagttgcaa ctgctacaac
    59821 tgcaagtgtt cttgacatcg caaatagcga caaacttctt gtcacacaag cagctatctc
    59881 taaaatcgag gaggttcttg cataatgaat ttgtatgatg ttatcaaaaa acctgtcatc
    59941 actgaaagct caatggctca acttgaagca gggaaatatg tatttgaagt tgacactcgt
    60001 gcacacaaac ttttgatcaa gcaagctgtt gaagctgctt tcgaaggtgt taaagttgcc
    60061 aatgttaaca caatcaacgt aaaaccaaaa gctaaacgtg ttggacgtta cactggtttt
    60121 actaacaaaa ctaaaaaagc tatcatcaca cttacagctg attctaaagc aatcgagttg
    60181 tttgctgctg aagctgaata atctaaggag gaaatatcgt gggaattcgt gtttataaac
    60241 caacaacaaa cggtcgccgt aatatgactt ctttggattt cgctgaaatc acaacaagca
    60301 ctcctgaaaa atcattgctt gttgcattga agagcaaggc tggtcgtaac aacaacggtc
    60361 gtatcacagt tcgtcaccaa ggtggtggac acaaacgttt ctaccgtttg gttgacttca
    60421 aacgtaataa agacaacgtt gaagcagttg ttaaaacaat cgagtacgat ccaaaccgtt
    60481 ctgcaaacat cgctcttgta cactacactg acggtgtgaa agcatacatc atcgctccaa
    60541 aaggtcttga agtaggtcaa cgtatcgttt caggtccaga agcagatatc aaagtcggaa
    60601 acgctcttcc acttgctaac atcccagttg gtactttgat tcacaacatc gagttgaaac
    60661 caggtcgtgg tggtgaattg gtacgtgctg ctggtgcatc tgctcaagta ttgggttctg
    60721 aaggtaaata cgttcttgtt cgtcttcaat caggtgaagt tcgtatgatt cttggaactt
    60781 gccgtgctac agttggtgtt gtcggaaacg aacaacatgg acttgtaaac cttggtaaag
    60841 caggacgtag ccgttggaaa ggtatccgcc caacagttcg tggttctgta atgaacccta
    60901 acgatcaccc acacggtggt ggtgaaggta aggcaccagt tggtcgtaaa gcaccatcta
    60961 ctccatgggg caaacctgct cttggtctta aaactcgtaa caagaaagcg aaatctgaca
    61021 aacttatcgt tcgtcgtcgc aacgagaaat aatattaaac tagtcgctta agcaactagt
    61081 aaatccgcca gctcggtagc gctccatagg agtgcaagcc gctgtggtac aacatttaaa
    61141 ggagaaaata taaaaatggg acgcagtctt aaaaaaggac ctttcgtcga tgagcatttg
    61201 atgaaaaaag ttgaagctca agctaacgac gaaaagaaaa aagttattaa aacttggtca
    61261 cgtcgatcaa cgatcttccc aagtttcatt ggttacacta ttgcagttta tgacggacgt
    61321 aaacacgtac ctgtttacat ccaagaagac atggtaggcc acaaacttgg tgaatttgca
    61381 ccaactcgta cttacaaagg tcacgctgca gacgacaaga aaacacgtag aaaataagga
    61441 gaacataaat ggcagaaatt acttcagcta aagcaatggc tcgtacagta cgtgtttcac
    61501 ctcgtaaatc acgtcttgtt cttgataaca tccgtggtaa aagcgtagcc gatgcaatcg
    61561 caatcttgac attcactcca aacaaagctg ctgaaatcat cttgaaagtt ttgaactcag
    61621 ctgtagctaa cgctgaaaac aactttggtt tggataaagc taacttggta gtatctgaag
    61681 cattcgcaaa cgaaggacca actatgaaac gtttccgtcc acgtgcgaaa ggttcagctt
    61741 caccaatcaa caaacgtaca gctcacatca ctgtagctgt tgcagaaaaa taaggaggta
    61801 aaatcgtggg tcaaaaagta catccaattg gtatgcgtgt cggcatcatc cgtgattggg
    61861 atgccaaatg gtatgctgaa aaagaatacg cggattacct tcatgaagat cttgcaatcc
    61921 gtaaattcgt tcaaaaagaa cttgctgacg cagcagtttc aactattgaa atcgaacgcg
    61981 cagtaaacaa agttaacgtt tcacttcaca ctgctaaacc aggtatggtt atcggtaaag
    62041 gtggtgctaa cgttgatgca ctccgtgcaa aacttaacaa attgactgga aaacaagtac
    62101 acatcaacat catcgaaatc aaacaacctg atttggatgc tcaccttgta ggtgaaggaa
    62161 ttgctcgtca attggagcaa cgtgttgctt tccgtcgtgc acaaaaacaa gcaatccaac
    62221 gtgcaatgcg tgctggagct aaaggaatca aaactcaagt atcaggtcgt ttgaacggtg
    62281 cagatatcgc ccgtgctgaa ggatactctg aaggaactgt tccgcttcac acacttcgtg
    62341 cagatatcga ttacgcttgg gaagaagcag atactacata tggtaaactt ggtgttaaag
    62401 tatggatcta ccgtggtgaa gttcttccag ctcgtaaaaa cactaaagga ggtaaataac
    62461 caatgttagt acctaaacgt gttaaacacc gtcgtgaatt ccgtggaaaa atgcgcggtg
    62521 aagcaaaagg tggaaaagaa gtagcattcg gtgaatacgg tcttcaagct acaactagcc
    62581 actggatcac taaccgccaa atcgaagctg ctcgtatcgc catgactcgt tacatgaaac
    62641 gtggtggtaa agtttggatt aaaatcttcc cacacaaatc atacactgct aaagctatcg
    62701 gtgtgcgtat gggatctggt aaaggggcac ctgaaggttg ggtagcacca gttaaacgtg
    62761 gtaaagtgat gttcgaaatc gctggtgtat ctgaagagat tgcacgtgaa gcgcttcgac
    62821 ttgctagcca caaattgcca gttaaatgta aattcgtaaa acgtgaagca gaataaggag
    62881 aaggcatgaa acttaatgaa gtaaaagaat ttgttaaaga acttcgtggt ctttctcaag
    62941 aagaactcgc gaagcgcgaa aacgaattga aaaaagaatt gtttgaactt cgtttccaag
    63001 ctgctactgg tcaattggaa caaacagctc gcttgaaaga agttaaaaaa caaatcgctc
    63061 gtatcaaaac agttcaatct gaagcgaaat aatagactag ggaaggagaa atttcaatgg
    63121 aacgcaataa tcgtaaagtt cttgttggac gtgttgtatc tgacaaaatg gacaagacaa
    63181 tcacagttgt agttgaaaca aaacgtaacc acccagtcta tggtaaacgt attaactact
    63241 ctaaaaaata caaagctcat gatgaaaaca atgttgccaa agaaggcgat atcgtacgta
    63301 tcatggaaac tcgcccgctt tcagctacaa aacgtttccg tcttgtagaa gttgttgaag
    63361 aagcggtcat catctaatca aacctgaaag gagaaaactg aaatgattca aacagaaact
    63421 cgtttgaaag tcgcagacaa cagcggtgct cgcgaaatct tgactatcaa agttcttggt
    63481 ggttcaggac gtaaatttgc aaacatcggt gatgttatcg tggcatctgt aaaacaagct
    63541 actcctggtg gtgcggttaa aaaaggtgac gttgttaaag cagttatcgt tcgtactaaa
    63601 tcaggtgctc gtcgtgctga tggttcatac atcaaatttg acgaaaacgc agcagttatc
    63661 atccgtgaag acaaaactcc tcgcggaaca cgtatctttg gcccagttgc acgtgaattg
    63721 cgtgaaggtg gcttcatgaa gatcgtgtca cttgctccag aagtacttta atttttagga
    63781 acaaactagt cccctagctt caagctaggg tgcccttatg ggcgtaagaa aaatcaagga
    63841 gaaacctaat gtttgtaaaa aaaggcgaca aagttcgcgt aatcgctggt aaagataagg
    63901 gaacagaagc tgttgtcctt actgcccttc caaaagtaaa caaagttatc gttgaaggtg
    63961 ttaacattgt taagaaacac caacgtccaa ctaacgagct tcctcaaggt ggtatcatcg
    64021 agaaagaagc agctatccac gtatcaaatg ttcaagtttt ggataaaaat ggtgtagctg
    64081 gtcgtgttgg ttacaaattt gtagacggta aaaaagttcg ctacaacaaa aaatcaggcg
    64141 aagtgcttga ttaatcacga aggaaaggag aagtataatg gcaaatcgtt taaaagaaaa
    64201 atatcttaat gaagtagttc ctgctttgac agaacaattc aactactcat cagtgatggc
    64261 tgtgcctaaa gtagataaga ttgttttgaa catgggtgtt ggtgaagctg tatcaaacgc
    64321 taaaagcctt gaaaaagctg ctgaagaatt ggcacttatc tcaggtcaaa aaccacttat
    64381 cactaaagct aaaaaatcaa tcgccggctt ccgtcttcgt gaaggtgttg cgatcggtgc
    64441 aaaagttacc cttcgtggtg aacgtatgta cgaattcttg gataaattgg tatcagtttc
    64501 acttccacgt gtacgtgact tccacggtgt cccaacaaaa tcatttgatg gacgcgggaa
    64561 ctacacactt ggtgtgaaag aacaattaat cttcccagaa atcaacttcg atgacgttga
    64621 caaaactcgt ggtcttgaca tcgttatcgt aacaactgct aacactgacg aagagtcacg
    64681 tgcattgctt acaggccttg gaatgccttt tgcaaaataa tataggaggt aaatctaatg
    64741 gctaaaaaat caatggtagc tagagaggct aaacgccaaa aaattgttga ccgttatgct
    64801 gaaaaacgtg ctgcattaaa ggcggcaggg gactacgaag gtttatctaa attacctcgc
    64861 aacgcctcac cgactcgttt acataatcgt tgtagggtta cggggcgccc acattcagtt
    64921 taccgcaaat ttggtctgag tcgtatcgct tttcgcgaac ttgcgcataa aggtcaaatt
    64981 cctggtgtaa caaaagcatc ttggtaattt aagatatcaa gagtgtcaaa actccaagta
    65041 aaaataggaa acttgacgaa gaaactaaag tttctaggaa agtttatctt tttcacacag
    65101 agtttagccc gggttcaatt gggcttgcca atttgaacac gagctacagc tttggcaaaa
    65161 aagaccaatt tgctttggag cattgcttct gcattaaatt gtctattttt gctcgtgctg
    65221 ttacgctctt tgtatcatgt attaactagc aagtgcaact tgcaaactac tagtaagagg
    65281 agaaaaacaa aatggttatg actgacccaa tcgcagactt cctaactcgt attcgtaatg
    65341 ctaaccaagc taaacacgaa gtacttgaag tacctgcatc aaacatcaaa aaagggattg
    65401 ctgaaatcct taaacgcgaa ggttttgtaa aaaacgttga aatcattgaa gatgacaaac
    65461 aaggcgtcat ccgtgtattt cttaaatacg gaccaaatgg tgagaaagtt atcactaact
    65521 tgaaacgtgt ttctaaacca ggacttcgtg tctacaaaaa acgtgaagac cttccaaaag
    65581 ttcttaacgg acttggaatt gccatccttt caacttctga aggtttgctt actgataaag
    65641 aagcacgcca aaagaatgtt ggtggtgagg ttatcgctta cgtttggtaa aatcaagata
    65701 caaagctcgt aaagaacaaa gcaaaattag gaagttggag aagtttgttt acaaacaagc
    65761 caacttatct attttgcaca gttcttagag cgtgttcagt tcagctcttg aactaaataa
    65821 gtatctgaac cccgtgaaaa ctggccgttc tggcctgaca atttaacagg agaaaataaa
    65881 catgtcacgt attggtaata aagttatcgt gttgcctgct ggtgttgaac tcgctaacaa
    65941 tgacaacgtt gtaactgtaa aaggacctaa aggagaactt actcgtgagt tctcaaaaga
    66001 tattgaaatc cgtgtggaag gtactgaaat aactcttcac cgtccaaacg attcaaaaga
    66061 aatgaaaact atccacggaa ctactcgtgc ccttttgaac aacatggttg ttggtgtatc
    66121 agaaggattc aagaaagaac ttgaaatgcg tggggttggt taccgtgcac agcttcaagg
    66181 atctaaactt gttttggctg ttggtaaatc tcatccagac gaagttgaag ctccagaagg
    66241 aattactttt gaacttccaa acccaacaac aatcgttgtt agcggaattt caaaagaagt
    66301 agttggtcaa acagctgctt acgtacgtag ccttcgttca ccagaaccat ataaaggtaa
    66361 aggtatccgt tacgttggtg aattcgttcg ccgtaaagaa ggtaaaacag gtaaataatg
    66421 ttgagtggtt gatcatcaac caccaaccta ttttccaact ttgtgcatag cacacgattt
    66481 aaaactaaag aggtgaaaac tgtgatttca aaaccagata aaaacaaact ccgccaaaaa
    66541 cgccaccgtc gcgttcgcgg aaaactctct ggaactgctg atcgcccacg tttgaacgta
    66601 ttccgttcta atacaggcat ctacgctcaa gtgattgatg acgtagcggg tgtaacgctc
    66661 gcaagtgctt caactcttga taaagaagtt tcaaaaggaa ctaaaactga acaagccgtt
    66721 gctgtcggta aactcgttgc agaacgtgca aacgctaaag gtatttcaga agtggtgttc
    66781 gaccgcggtg gatatctata tcacggacgt gtgaaagctt tggctgatgc agctcgtgaa
    66841 aacggattga aattctaata ggaggacact agaaaatggc atttaaagac aatgcagttg
    66901 aattagaaga acgcgtagtt gctgtcaacc gtgttacaaa agttgttaaa ggtggacgtc
    66961 gtcttcgttt cgcagctctt gttgttgttg gtgaccacaa tggtcgcgta ggatttggta
    67021 ctggtaaagc tcaagaagtt ccagaagcaa tccgtaaagc agtagatgat gctaagaaaa
    67081 acttgatcga agttcctatg gttggaacaa caatcccaca cgaagttctt tcagaattcg
    67141 gtggagctaa agtattgttg aaacctgctg tagaaggttc tggagttgcc gctggtggtg
    67201 cagttcgtgc cgttgtggaa ttggcaggtg tggcagatat tacatctaaa tcacttggtt
    67261 ctaacactcc aatcaacatt gttcgtgcaa ctgttgaagg tttgaaacaa ttgaaacgcg
    67321 ctgaagaaat tgctgccctt cgtggtattt cagtttctga tttggcataa gaaaggggat
    67381 aaaatggctc aaattaaaat tactttgact aagtctccaa tcggacgcat tccatcacaa
    67441 cgtaaaactg ttgtagcact tggacttggc aaattgaaca gctctgttat taaagaagat
    67501 aacgctgcta tccgtggtat gatcacagca gtatctcact tagtaacagt tgaagaagta
    67561 aactaatgaa gttttagggg atgtgcactg taccatcccc taaaactaga tatagtcatc
    67621 tatgatgaca tcgtataggc gagttgatgg gggagacaac cttttctccc ttatcggcgc
    67681 tagcatttta caaaagagga gaaaataaaa atgaaacttc atgaattgaa acctgcagaa
    67741 ggttctcgta aagtacgtaa ccgcgttggt cgtggtactt catcaggtaa cggtaaaaca
    67801 tctggtcgtg gtcaaaaagg tcaaaaagct cgtagcggtg gcggagttcg ccttggtttt
    67861 gaaggtggac aaactccatt gttccgtcgt cttccaaaac gtggattcac taacatcaac
    67921 gctaaagaat acgcaattgt gaaccttgac caattgaacg tctttgaaga tggtgctgaa
    67981 gtaactccag ttgttcttat cgaagcagga attgttaaag ctgaaaagtc aggtattaaa
    68041 attcttggta acggtgagtt gactaagaaa ttgactgtga aagcagctaa attctctaaa
    68101 tcagctgaag aagctatcac tgctaaaggt ggttcagtag aagtcatcta agagaggtga
    68161 cctatgtttt ttaaattatt aagagaagct cttaaagtca agcaggttcg atcaaaaatt
    68221 ttatttacaa tttttatcgt tttggtcttt cgtatcggaa ctagcattac agttcctggt
    68281 gtgaatgcca atagcttgaa tgctttaagt ggattatcct tcttaaacat gttgagcttg
    68341 gtgtcgggga atgccctaaa aaacttttcg atttttgccc taggagttag tccctatatc
    68401 actgcttcta ttgttgtcca actcttgcaa atggatattt tacccaagtt tgtagagtgg
    68461 ggtaaacaag gggaagtagg tcgaagaaaa ttgaatcaag ctactcgtta tattgctcta
    68521 gttctcgctt ttgtgcaatc tatcgggatt acagctggtt ttaatacctt ggctggagct
    68581 caattgatta aaactgcttt aactccacaa gtttttctga cgattggtat catcttaaca
    68641 gctggtagta tgattgtcac ttggttgggt gagcaaatta cagataaggg atacggaaac
    68701 ggtgtttcca tgattatctt tgccgggatt gtttcctcaa ttccagagat gattcagggc
    68761 atctatgtgg actactttgt gaacgtccca agtagccgta tcacttcatc tatcattttc
    68821 gtaatcattt tgattattac tgtattgttg attatttact ttacaactta tgttcaacaa
    68881 gcagaataca aaattccaat ccaatatact aaggttgcac aaggtgctcc atctagctct
    68941 taccttccgt taaaggtaaa tcctgctgga gttatccctg ttatctttgc cagttcgatt
    69001 actgcagcgc ctgcggctat tcttcagttt ttgagtgcca caggtcatga ttgggcttgg
    69061 gtaagggtag cacaagagat gttggcaact acttctccaa ctggtattgc catgtatgct
    69121 ttgttgatta ttctctttac attcttctat acgtttgtac agattaatcc tgaaaaagca
    69181 gcagagagcc tacaaaagag tggtgcctat atccatggag ttcgtcctgg taaaggtaca
    69241 gaagaatata tgtctaaact tcttcgtcgt cttgcaactg ttggttccct cttccttggt
    69301 gtgatttcca ttttaccgat tgcagctaaa gatgtatttg gtctttctga tgttgttgcc
    69361 tttggtggaa caagtctctt gatcattatc tctacaggta tcgaaggaat caagcaattg
    69421 gaaggttacc tattgaaacg taagtatgtt ggtttcatgg acagaacaga ataaaagtat
    69481 ttactgaatc agtaaatgct gagggagtgg aggtttaaac tctgacattt gtaagagttg
    69541 gatctcccct cttctatttt gtttttaaat aggggtgaaa agactttttg cttctattta
    69601 aaaataaaat aaggagatca aatcatgaat cttttgatta tgggcttacc tggtgcaggt
    69661 aagggaactc aagcagcaaa aatcgtagaa caattccatg ttgcacatat ctcaacaggt
    69721 gatatgttcc gcgctgcaat ggcaaatcaa actgaaatgg gtgttcttgc taagtcatat
    69781 attgacaagg gtgaattggt tcctgacgaa gttacaaatg gaatcgtaaa agaacgcctt
    69841 tcacaagatg atattaaaga aacaggattc ttattggatg gttacccacg tacaattgaa
    69901 caagctcatg ccttggacaa aacattggct gaacttggca ttgaactaga aggtgttatc
    69961 aatattgaag tgaaccctga cagcctcttg gaacgtttga gtggccgtat catccaccgc
    70021 gtaactggag aaactttcca caaggtcttt aacccaccag ttgactataa agaagaagat
    70081 tactaccaac gtgaagatga taagcctgag acagtaaaac gtcgtttgga tgttaatatt
    70141 gctcaaggag aaccaatcat tgctcactac cgtgccaaag gtttggttca tgacatcgaa
    70201 ggtaatcaag atatcaatga tgtcttctca gatattgaaa aagtattgac aaatttgaaa
    70261 taaagcgttt ttcatacttg caaaaattcg ctacaaatgt tatactgaga tagtctgact
    70321 tataattgtt gtctctgtgt ctagaggcat cgaatcgaaa tttatggagg tgcttttgcg
    70381 tggcaaaaga cgatgtgatt gaagttgaag gcaaagtagt tgatacaatg ccgaatgcaa
    70441 tgtttacggt tgaacttgaa aatggacatc agattttagc aacagtttct ggtaaaattc
    70501 gtaaaaacta tattcgtatt ttagcgggag atcgtgttac tgtcgaaatg agtccatatg
    70561 acttgacacg tggacgtatc acttaccgct ttaaataatc gaaaaacttg gagggataag
    70621 aaatgaaagt aagaccatcg gtcaaaccaa tttgcgaata ctgtaaagtt attcgtcgta
    70681 atggtcgtgt tatggtaatt tgcccagcaa atccaaaaca caaacaacgt caaggataag
    70741 atagaaagga gaaaacatgg ctcgtattgc tggagttgat attccaaatg acaaacgcgt
    70801 agtaatctca ttgacttatg tttatggtat cggacttgca acatctaaga aaattttggc
    70861 tgctgctgga atctcagaag atgttcgtgt acgtgatctt acatcagatc aagaagatgc
    70921 tatccgtcgt gaagtggatg caatcaaagt tgaaggtgac cttcgtcgtg aagtaaactt
    70981 gaacatcaaa cgtttgatgg aaatcggttc ataccgtggt atccgtcacc gtcgtggact
    71041 tcctgtccgt ggacaaaaca ctaaaaacaa cgctcgcact cgtaaaggta aagctgttgc
    71101 gattgctggt aagaaaaaat aatataggag gtaaaagtct tggctaaacc aacacgtaaa
    71161 cgtcgtgtga aaaagaatat cgaatctggt attgctcata ttcacgctac atttaataac
    71221 actattgtta tgattactga tgtgcatggt aatgcaattg cttggtcatc agctggtgct
    71281 cttggtttca aaggttctcg taaatctaca ccattcgctg ctcaaatggc ttctgaagct
    71341 gctgctaaat ctgcacaaga acacggtctt aaatcagttg aagttactgt aaaaggtcca
    71401 ggttctggtc gtgagtcagc tattcgtgcg cttgctgccg ctggtcttga agtaacagca
    71461 attcgtgatg tgactccagt gccacacaat ggtgctcgtc ctccaaaacg tcgccgtgta
    71521 taatcatcgc attacactgc ttttcgttta agagggagta actaaatgat cgagtttgaa
    71581 aaaccaaata taacaaaaat tgatgaaaat aaagattatg gcaagtttgt aatcgaacca
    71641 cttgaacgtg gctacggtac aactcttggt aactctcttc gtcgtgtact tctagcttct
    71701 ctaccaggag cagctgtgac atctatcaac attgatggtg tgttacatga gtttgacaca
    71761 gttccaggtg ttcgtgaaga cgtgatgcaa atcattctga acattaaagg aattgcagtg
    71821 aaatcgtacg ttgaagacga aaaaatcatc gaactggatg ttgaaggtcc tgctgaagta
    71881 acagctggtg acattttgac agatagcgat attgaaattg taaatccaga tcattatctc
    71941 tttacaatcg gtgaaggttc ttctctaaaa gcgactatga ctgttaacag tggtcgtgga
    72001 tatgtacctg ctgatgaaaa taaaaaggat aatgcaccag ttggaacact tgctgtagat
    72061 tctatttata caccagttac aaaagtcaac tatcaagtgg aacctgctcg tgtaggtagc
    72121 aatgatggtt tcgacaaatt aacccttgaa atcttgacaa atggaacaat tattccagaa
    72181 gatgctttag ggctttcagc acgtattttg acagaacatc ttgatttgtt tacaaatctt
    72241 actgagattg ctaagtcaac tgaagtgatg aaagaagctg atactgaatc tgacgaccgt
    72301 attttagatc gtacgattga ggaactggac ttgtctgtgc gttcatacaa ctgtttaaaa
    72361 cgtgccggta tcaatactgt gcatgatttg acagaaaaat ctgaagcaga gatgatgaaa
    72421 gtacgaaatc ttggacgcaa gagtttggaa gaagtgaaac tcaaactcat tgatttgggt
    72481 cttggattaa aagataaata aaggaggaat acatggctta ccgtaaacta ggacgcacta
    72541 gctcacaacg taaagcaatg cttcgcgatt tgacaactga ccttttgatc aacgaatcaa
    72601 tcgtgacaac tgaagctcgt gctaaagaaa tccgtaaaac tgttgaaaaa atgattactc
    72661 taggtaaacg tggtgatttg catgcacgtc gtcaagcagc tgctttcgta cgtaatgaaa
    72721 tcgcatctga aaactatgat gaagcaactg ataagtacac ttctactaca gcacttcaaa
    72781 aattgttctc agaaatcgca cctcgttatg ctgaacgtaa cggtggatac actcgtatcc
    72841 ttaaaactga accacgtcgt ggtgatgcag cgccaatggc gatcatcgaa ttagtataaa
    72901 atcatcaatt ttgttgagtg ttatgatgat ggagtcttgt gctcttagtc tagctctggt
    72961 ctaccgctag gatttcggtc ctagcgggaa cactcatcat aagttgggat agtagacgct
    73021 tgtttacgaa attgtttttt tcttaagaac aacttcgtaa gcaggcgttt ttgagtattt
    73081 tcgttagaat tatgctatac tatttgaaaa gaatcctgtt taatgttaag gtttcttatt
    73141 ttaagaagaa ttggagttta cttatgaaag ccattataac tgttgttggt aaagataaat
    73201 ctggaattgt tgcaggtgtt tctggtaaaa ttgcagaatt aggattgaat attgacgata
    73261 tctctcaaac tgtattggat gaatatttta cgatgatggc tgttgtatct agtgatgaaa
    73321 agcaagattt tacctatctt cgtaatgaat ttgaagcttt tgggcaaact ttgaatgtaa
    73381 aaatcaatat tcagagtgca gcgattttcg aagctatgta taatatctag gaggtcatca
    73441 tggatattag acaagttact gaaaccatcg ccatgattga ggagcaaaac ttcgatatta
    73501 gaaccattac catggggatt tctcttttgg actgtatcga tccaaatatc aatcgtgctg
    73561 cggagaaaat ctatcaaaaa attacgacaa aggcggctaa tttagtagct gttggtgatg
    73621 aaattgcggc tgagttggga attcctatcg ttaataagcg tgtatcggtg acacctattt
    73681 ctctgattgg ggcagcgaca gatgcgacgg actacgtggt tctggcaaaa gcgcttgata
    73741 aggctgcgaa agagattggt gtggacttta ttggtggttt ttctgcctta gtacaaaaag
    73801 gttatcaaaa gggagatgag attctcatca attccattcc tcgcgctttg gctgagacgg
    73861 ataaggtctg ctcgtcagtc aatatcggct caaccaagtc tggtattaat atgacggctg
    73921 tggcagatat gggacgaatt atcaaggaaa cagcaaatct ttcagatatg ggagtggcca
    73981 agttggttgt attcgctaat gctgttgagg acaatccatt tatggcgggt gcctttcatg
    74041 gtgttgggga agcagatgtt atcatcaatg tcggagtttc tggtcctggt gtggtgaaac
    74101 gtgctttgga aaaagttcgt ggacagagct ttgatgtagt agccgaaaca gttaagaaaa
    74161 ctgcctttaa aatcactcgt atcggtcaat tggttggtca aatggccagt gagagactgg
    74221 gtgtggagtt tggtattgtg gacttgagtt tggcaccaac ccctgcggtt ggagactctg
    74281 tggcacgtgt ccttgaggaa atggggctag aaacagttgg cacgcatgga acgacagctg
    74341 ccttggccct cttgaacgac caagttaaaa agggtggagt gatggcctgt aaccaggtcg
    74401 gtggtctatc tggtgccttt atccctgttt ctgaggatga aggaatgatt gctgcagtgc
    74461 aaaatggctc tcttaattta gaaaaactag aagctatgac ggctatctgt tctgttggat
    74521 tggatatgat tgccatccca gaagatacgc ctgctgaaac tattgcggct atgattgcgg
    74581 atgaagcagc aatcggtgtt atcaacatga aaacaacagc tgttcgtatc attcccaaag
    74641 gaagagaagg cgatatgatt gagtttggtg gtctattagg aactgcacct gttatgaagg
    74701 ttaatggggc ttcgtctgtc gacttcatct ctcgcggtgg acaaatccca gcaccaattc
    74761 atagttttaa aaattaagaa aataggagaa attttaagtt ctatttaaga ttagacgtgt
    74821 atactata
//
LOCUS       DAVKMJ010000002        74101 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000002 DAVKMJ010000000
VERSION     DAVKMJ010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 74101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74101
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.002"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..2511)
                     /locus_tag="VW348_000092"
     CDS             complement(<1..2511)
                     /locus_tag="VW348_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU9745080.1"
                     /translation="MSLRNKIEQHIKELEGGKFQKLGDAYLSRKYNFNIVSLGSQEGT
                     DKTTKGIPDSYAVENGKYVYIMYGTHKSVISKLEGDIQSVKKKILEENIAEDKVGRLI
                     CCHTSSNITIKQKEDLEKMAEPYHLELIGINEIANDLTKIDFQYLAKEYLSISESTEQ
                     VWSINDFIRIHDESKTNAPISNDYIGDVSEIINTIKSSEKRIFLISAKPGTGKTRLAI
                     EICSLLDRNKYNIICVKSNNQDIYQDVKRNLNLHKENIVFIDDVNTTQNYISTLGLLN
                     TTSNIRFILTVRDYAKKDVINNIKVYGYNNIEPELIKDDNFKELLNQFSRNDFTNQEI
                     EHIKTISKSNPRIAVIAAKLSSSQDLTNFNDEIDILKDYYEEILNKNNIIYAEQKTLF
                     ILSYLKKIRLESLEENQEFNKLLKITDITNTDFKSAVEKLHERELCNIYNDKIVKIAD
                     QSLDDYIVIKFLINKKISILEILHELYPVNDQRVVQILNQCSNFIRKESDLEGVSDAV
                     KSYYYNESNFESDELKEKFLIQFGVLLPLEAISHVKNKIDNIESQVYTKTNFINQKDK
                     KGSIEDSVLNIVFVTTRTKYCSQILQLLLKYFDKNPNKISEVYSILEANYGLVTEREY
                     IDYTLAENTISELANLDLTKSYNQELIVTILKQFLKIEIERTETHEEKFTFGRYKVPD
                     SEKLKQYHRSILKLLANLYNIGSCETRFYIEKMLYDYRRKILTYSESHRNTIFGDLRN
                     IRKLFFNDIKNLSMIGEKIVYALHKAEVKENLPIVFDDYIISDRQKIYNNLTNPNHAW
                     FYDASEIKLQQIANSYSNVWLKIFNFANQFKHSLFMNDN"
     gene            complement(2758..3126)
                     /gene="rplL"
                     /locus_tag="VW348_000093"
     CDS             complement(2758..3126)
                     /gene="rplL"
                     /locus_tag="VW348_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEU9745081.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            complement(3202..3702)
                     /locus_tag="VW348_000094"
     CDS             complement(3202..3702)
                     /locus_tag="VW348_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEU9745082.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     misc_feature    complement(3741..3876)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3952..5211)
                     /locus_tag="VW348_000095"
     CDS             complement(3952..5211)
                     /locus_tag="VW348_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEU9745083.1"
                     /translation="MKVFQHVNIVTCDQNFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKCPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     gene            complement(5603..7351)
                     /locus_tag="VW348_000096"
     CDS             complement(5603..7351)
                     /locus_tag="VW348_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9745084.1"
                     /translation="MKRQTVNQTLKRLAVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKIAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLVIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(7353..9077)
                     /locus_tag="VW348_000097"
     CDS             complement(7353..9077)
                     /locus_tag="VW348_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9745085.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLSKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQKLWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFIILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(9135..10073)
                     /gene="msrB"
                     /locus_tag="VW348_000098"
     CDS             complement(9135..10073)
                     /gene="msrB"
                     /locus_tag="VW348_000098"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU9745086.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(10221..10292)
                     /locus_tag="VW348_000099"
                     /pseudo
     CDS             complement(10221..10292)
                     /locus_tag="VW348_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10368..11237)
                     /locus_tag="VW348_000100"
     CDS             complement(10368..11237)
                     /locus_tag="VW348_000100"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEU9745087.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAAAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(11239..12525)
                     /locus_tag="VW348_000101"
     CDS             complement(11239..12525)
                     /locus_tag="VW348_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEU9745088.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(12676..13413)
                     /gene="mecA"
                     /locus_tag="VW348_000102"
     CDS             complement(12676..13413)
                     /gene="mecA"
                     /locus_tag="VW348_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEU9745089.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(13613..14647)
                     /locus_tag="VW348_000103"
     CDS             complement(13613..14647)
                     /locus_tag="VW348_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU9745090.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPEDSAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(14676..16112)
                     /locus_tag="VW348_000104"
     CDS             complement(14676..16112)
                     /locus_tag="VW348_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEU9745091.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNNVSLLSTLLFLL
                     VSSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVM
                     VSILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRL
                     FERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSF
                     IAANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAM
                     GVLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPV
                     LDYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYI
                     MELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSE
                     SFFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(16128..17114)
                     /locus_tag="VW348_000105"
     CDS             complement(16128..17114)
                     /locus_tag="VW348_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9745092.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(17116..18219)
                     /locus_tag="VW348_000106"
     CDS             complement(17116..18219)
                     /locus_tag="VW348_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEU9745093.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDLEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(18209..19054)
                     /locus_tag="VW348_000107"
     CDS             complement(18209..19054)
                     /locus_tag="VW348_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU9745094.1"
                     /translation="MNNMTDLKAIQARSLEMADYFVAFCKEHDLLCYLCGGGAIGTLR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSYKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKDPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(19333..20607)
                     /gene="psr"
                     /locus_tag="VW348_000108"
     CDS             complement(19333..20607)
                     /gene="psr"
                     /locus_tag="VW348_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEU9745095.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(20604..21452)
                     /gene="pheA"
                     /locus_tag="VW348_000109"
     CDS             complement(20604..21452)
                     /gene="pheA"
                     /locus_tag="VW348_000109"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEU9745096.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     NYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEGVTIPLQSQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(21449..21925)
                     /locus_tag="VW348_000110"
     CDS             complement(21449..21925)
                     /locus_tag="VW348_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEU9745097.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(21918..23201)
                     /gene="aroA"
                     /locus_tag="VW348_000111"
     CDS             complement(21918..23201)
                     /gene="aroA"
                     /locus_tag="VW348_000111"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEU9745098.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSASFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(23293..23631)
                     /locus_tag="VW348_000112"
     CDS             complement(23293..23631)
                     /locus_tag="VW348_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEU9745099.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(23642..24745)
                     /locus_tag="VW348_000113"
     CDS             complement(23642..24745)
                     /locus_tag="VW348_000113"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEU9745100.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLESIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITKNTDYTVVIK"
     gene            complement(24755..25921)
                     /gene="aroC"
                     /locus_tag="VW348_000114"
     CDS             complement(24755..25921)
                     /gene="aroC"
                     /locus_tag="VW348_000114"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEU9745101.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(25931..26998)
                     /locus_tag="VW348_000115"
     CDS             complement(25931..26998)
                     /locus_tag="VW348_000115"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEU9745102.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(27017..27871)
                     /locus_tag="VW348_000116"
     CDS             complement(27017..27871)
                     /locus_tag="VW348_000116"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEU9745103.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLAETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEAHLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(27861..28538)
                     /locus_tag="VW348_000117"
     CDS             complement(27861..28538)
                     /locus_tag="VW348_000117"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEU9745104.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(28535..29698)
                     /locus_tag="VW348_000118"
     CDS             complement(28535..29698)
                     /locus_tag="VW348_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEU9745105.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFISKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(30383..32017)
                     /locus_tag="VW348_000119"
     CDS             complement(30383..32017)
                     /locus_tag="VW348_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745106.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMIICFSNIAIHFPFEEIPIYFSLMIAILLVIAFSTSLTAFYNVFYESK
                     DLISYRPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVALVMVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVDPFSTEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFFPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPVLTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAINLGVGALIVLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(31998..32747)
                     /locus_tag="VW348_000120"
     CDS             complement(31998..32747)
                     /locus_tag="VW348_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9745107.1"
                     /translation="MIEFQNVSKLYGDKKALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVED
                     LRKDYPDQSLESIYLSLAGRKEEVADASQGH"
     gene            32926..34380
                     /locus_tag="VW348_000121"
     CDS             32926..34380
                     /locus_tag="VW348_000121"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEU9745108.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(34470..37088)
                     /gene="alaS"
                     /locus_tag="VW348_000122"
     CDS             complement(34470..37088)
                     /gene="alaS"
                     /locus_tag="VW348_000122"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEU9745109.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQPKIQELLDAVAGKL"
     gene            complement(37110..37595)
                     /locus_tag="VW348_000123"
     CDS             complement(37110..37595)
                     /locus_tag="VW348_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEU9745110.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(37870..38109)
                     /locus_tag="VW348_000124"
     CDS             complement(37870..38109)
                     /locus_tag="VW348_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745111.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLNDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(38378..39448)
                     /locus_tag="VW348_000125"
     CDS             complement(38378..39448)
                     /locus_tag="VW348_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9745112.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGSEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(39445..40218)
                     /locus_tag="VW348_000126"
     CDS             complement(39445..40218)
                     /locus_tag="VW348_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9745113.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(40215..41021)
                     /locus_tag="VW348_000127"
     CDS             complement(40215..41021)
                     /locus_tag="VW348_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9745114.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(41002..42159)
                     /locus_tag="VW348_000128"
     CDS             complement(41002..42159)
                     /locus_tag="VW348_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9745115.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(42320..43225)
                     /gene="murB"
                     /locus_tag="VW348_000129"
     CDS             complement(42320..43225)
                     /gene="murB"
                     /locus_tag="VW348_000129"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEU9745116.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(43337..44089)
                     /locus_tag="VW348_000130"
                     /pseudo
     CDS             complement(43337..44089)
                     /locus_tag="VW348_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
     gene            complement(44099..44830)
                     /gene="budA"
                     /locus_tag="VW348_000131"
     CDS             complement(44099..44830)
                     /gene="budA"
                     /locus_tag="VW348_000131"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEU9745117.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            complement(45314..45835)
                     /locus_tag="VW348_000132"
     CDS             complement(45314..45835)
                     /locus_tag="VW348_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcin A-M57"
                     /protein_id="HEU9745118.1"
                     /translation="MKFKKIVTSALVVLSLFSIMSPSIASVRVFADDVTTTEVSEIST
                     QEQKQIDDVANVLEQMFRNGVNEKNFTEYVYKNFSQKDIALAENELETNINNPYDRVP
                     WDEMGGCIAGKIRDEFFAMINVSLIVKYAQKKAWSELAKVVLRFVKANGLKTNIYIIA
                     GQLAIWAVQCGLE"
     gene            46266..47537
                     /locus_tag="VW348_000133"
     CDS             46266..47537
                     /locus_tag="VW348_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEU9745119.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(47557..48381)
                     /locus_tag="VW348_000134"
     CDS             complement(47557..48381)
                     /locus_tag="VW348_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU9745120.1"
                     /translation="MFIYEIKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGK
                     LVVATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQ
                     TGKADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQ
                     KGTVPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAV
                     ATVSLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(48528..49181)
                     /gene="phoU"
                     /locus_tag="VW348_000135"
     CDS             complement(48528..49181)
                     /gene="phoU"
                     /locus_tag="VW348_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU9745121.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(49193..49951)
                     /gene="pstB"
                     /locus_tag="VW348_000136"
     CDS             complement(49193..49951)
                     /gene="pstB"
                     /locus_tag="VW348_000136"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU9745122.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLNPQHKETEDYITGKFG"
     gene            complement(49964..50767)
                     /gene="pstB"
                     /locus_tag="VW348_000137"
     CDS             complement(49964..50767)
                     /gene="pstB"
                     /locus_tag="VW348_000137"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU9745123.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(50778..51662)
                     /gene="pstA"
                     /locus_tag="VW348_000138"
     CDS             complement(50778..51662)
                     /gene="pstA"
                     /locus_tag="VW348_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU9745124.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(51652..52569)
                     /gene="pstC"
                     /locus_tag="VW348_000139"
     CDS             complement(51652..52569)
                     /gene="pstC"
                     /locus_tag="VW348_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU9745125.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(52569..53447)
                     /gene="pstS"
                     /locus_tag="VW348_000140"
     CDS             complement(52569..53447)
                     /gene="pstS"
                     /locus_tag="VW348_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEU9745126.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(54021..55325)
                     /locus_tag="VW348_000141"
     CDS             complement(54021..55325)
                     /locus_tag="VW348_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEU9745127.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEAFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(55326..56099)
                     /locus_tag="VW348_000142"
     CDS             complement(55326..56099)
                     /locus_tag="VW348_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEU9745128.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGHLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(56089..56367)
                     /locus_tag="VW348_000143"
     CDS             complement(56089..56367)
                     /locus_tag="VW348_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEU9745129.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(56367..56768)
                     /locus_tag="VW348_000144"
     CDS             complement(56367..56768)
                     /locus_tag="VW348_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEU9745130.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(56978..57595)
                     /locus_tag="VW348_000145"
     CDS             complement(56978..57595)
                     /locus_tag="VW348_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEU9745131.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLYLKSRRK"
     gene            complement(57585..58358)
                     /locus_tag="VW348_000146"
     CDS             complement(57585..58358)
                     /locus_tag="VW348_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEU9745132.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(58369..59106)
                     /locus_tag="VW348_000147"
     CDS             complement(58369..59106)
                     /locus_tag="VW348_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEU9745133.1"
                     /translation="MCLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKV"
     gene            complement(59111..60241)
                     /locus_tag="VW348_000148"
     CDS             complement(59111..60241)
                     /locus_tag="VW348_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEU9745134.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(60325..60714)
                     /locus_tag="VW348_000149"
     CDS             complement(60325..60714)
                     /locus_tag="VW348_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEU9745135.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(60730..61113)
                     /locus_tag="VW348_000150"
     CDS             complement(60730..61113)
                     /locus_tag="VW348_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEU9745136.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(61114..61902)
                     /locus_tag="VW348_000151"
     CDS             complement(61114..61902)
                     /locus_tag="VW348_000151"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEU9745137.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFSLRVSQWLSVVFIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(61895..62830)
                     /locus_tag="VW348_000152"
     CDS             complement(61895..62830)
                     /locus_tag="VW348_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEU9745138.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(62960..63136)
                     /locus_tag="VW348_000153"
     CDS             complement(62960..63136)
                     /locus_tag="VW348_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEU9745139.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(63276..63983)
                     /locus_tag="VW348_000154"
     CDS             complement(63276..63983)
                     /locus_tag="VW348_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEU9745140.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            64134..65162
                     /gene="queA"
                     /locus_tag="VW348_000155"
     CDS             64134..65162
                     /gene="queA"
                     /locus_tag="VW348_000155"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEU9745141.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKIVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(65823..66212)
                     /locus_tag="VW348_000156"
     CDS             complement(65823..66212)
                     /locus_tag="VW348_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU9745142.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(66316..66957)
                     /locus_tag="VW348_000157"
     CDS             complement(66316..66957)
                     /locus_tag="VW348_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002871528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU9745143.1"
                     /translation="MNTSFAHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRFEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGYVTEQVTVD
                     RKEATDTVIKVPAKSKIEEVLVPFATKYEADNDLSAGQEQEITLGKNGKTVTTITYNV
                     DGKSGQVTESTLSQKKTLKQELLKKEPSPKFLSKKFQSKQNISMAQLLIKVKK"
     gene            complement(67671..68222)
                     /locus_tag="VW348_000158"
     CDS             complement(67671..68222)
                     /locus_tag="VW348_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9745144.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSTENLTYVTWD
                     PHPDVEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGHGMMTEALKAVLDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(68621..69445)
                     /gene="nadE"
                     /locus_tag="VW348_000159"
     CDS             complement(68621..69445)
                     /gene="nadE"
                     /locus_tag="VW348_000159"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEU9745145.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(69442..70902)
                     /locus_tag="VW348_000160"
     CDS             complement(69442..70902)
                     /locus_tag="VW348_000160"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEU9745146.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIYNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFPEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DENGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(71018..71506)
                     /locus_tag="VW348_000161"
     CDS             complement(71018..71506)
                     /locus_tag="VW348_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745147.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(71496..71705)
                     /locus_tag="VW348_000162"
     CDS             complement(71496..71705)
                     /locus_tag="VW348_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9745148.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(72090..72818)
                     /locus_tag="VW348_000163"
     CDS             complement(72090..72818)
                     /locus_tag="VW348_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9745149.1"
                     /translation="MKLNKLNFLKESIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     GTSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYAWNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVLITTIILLYFFTLKKSKKYSF"
     gene            complement(72834..73625)
                     /locus_tag="VW348_000164"
     CDS             complement(72834..73625)
                     /locus_tag="VW348_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000928765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9745150.1"
                     /translation="MNFALNKGEIVGLVGRNGVGKSMLMKILAQNNQPTSGNIISSDN
                     IGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLAVLKNLALHENVGILISSHKL
                     EDIEEICERVLFLESGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
BASE COUNT        22206 a        16439 c        13503 g        21953 t
ORIGIN      
        1 attgtcattc ataaataagc tatgtttgaa ttgatttgca aaattaaaaa ttttaagcca
       61 aacatttgaa tagctatttg caatttgttg tagtttaatt tcagaagcat cataaaacca
      121 agcatggtta ggatttgtta aattattata tattttttgt ctgtcagaaa ttatataatc
      181 atcaaaaaca atcggtaaat tttctttcac ttcggcttta tgcaaagcat aaactatttt
      241 ttctccaatc atagataagt ttttaatgtc attaaaaaat aatttcctaa tatttctcaa
      301 atctccaaag atagtattac gatgactttc tgaataggtc aaaatttttc ttctgtaatc
      361 atatagcatt ttctcaatat aaaatctagt ttcacaactc cctatattat acaaattcgc
      421 taaaagtttt agtatacttc tatgatactg ttttaatttt tcactatccg ggactttata
      481 gcgcccaaaa gtaaatttct cttcatgagt ctctgttctt tcgatttcaa ttttaagaaa
      541 ctgcttcaaa attgtcacga ttaattcttg gttataactt ttcgtcaaat caagattagc
      601 aagttcagaa atggtatttt cagctaaggt ataatcaata tattctcttt ctgtaaccaa
      661 cccgtagttt gcttcaagaa tactataaac ctcagaaatt ttattaggat ttttatcaaa
      721 gtactttaac aataattgga gaatttgact acaatatttt gtccgtgtag ttacaaatac
      781 aatatttaaa actgaatcct caatagatcc ctttttatcc ttctgattaa taaaattagt
      841 ctttgtataa acctgagact ctatattatc aattttattt ttaacgtgtg aaattgcttc
      901 taaaggaagt aatactccaa attgtattaa aaacttttct ttaagttcat cactttcaaa
      961 attactttca ttgtaataat atgatttaac tgcatcagaa acgccttcta aatcactctc
     1021 tttcctaata aaattggaac attgatttag tatttgaaca actctttggt cgtttactgg
     1081 atataactca tgtaaaattt ctaaaattga tattttcttg ttaattaaaa acttgataac
     1141 tatataatca tctaatgatt gatctgctat ctttacaatt ttgtcgttat aaatattaca
     1201 caactctctt tcatgaagct tctccactgc actcttaaag tcagtatttg ttatgtcagt
     1261 tatttttagt aatttattga attcctggtt ctcttctaaa ctttccagtc taatcttttt
     1321 taagtaagat aaaataaata gagtcttttg ttctgcataa ataatgttgt ttttatttaa
     1381 aatttcttca tagtaatctt ttaaaatatc aatctcatca ttaaaattag tcaaatcctg
     1441 agagctagat aactttgctg caatgactgc aatacgcgga ttgcttttag atatcgtttt
     1501 tatatgttca atttcttgat tggtaaaatc gtttcgagaa aattgattga gtaattcctt
     1561 aaaattatca tcttttataa gttctggctc aatattattg tacccataaa ctttaatatt
     1621 attgattaca tcttttttag cataatcacg taccgtaaga ataaaccgaa tattactagt
     1681 cgtgttcagt agcccaagtg tagaaatata attttgtgta gtattaacat catcaataaa
     1741 aacaatattt tctttgtgta aatttagatt gcgttttaca tcttggtaaa tatcctgatt
     1801 attgctcttg acacaaataa tgttatattt atttcgatcc agcaaagagc aaatttcaat
     1861 tgctaatcta gttttccctg ttccaggctt agcagatatt aagaagattc gtttttcact
     1921 tgatttaatg gtatttataa tttcacttac atctccaata tagtcatttg atataggagc
     1981 attagtttta ctctcatcat gaattcttat gaagtcattg atagaccaaa cttgctctgt
     2041 agattcactg attgatagat actcttttgc taaatattga aaatctatct ttgtaagatc
     2101 attagcaatt tcattaattc caatcaattc tagatgataa ggctcagcca ttttttctag
     2161 atcttctttt tgtttaattg ttatatttga agaagtatga caacaaataa gtctcccaac
     2221 tttatcttca gcaatatttt cctctaaaat ttttttctta actgactgaa tgtctccttc
     2281 taatttagat attacagact tatgggtgcc atacataata taaacatatt taccattttc
     2341 gacagcgtaa gaatctggga tccctttagt tgttttatct gttccttcct gtgagcctaa
     2401 tgaaacaata ttaaaattgt attttctact taggtacgcg tcacctagtt tttgaaactt
     2461 ccctccctct agctctttaa tatgttgctc aattttattt cttaaactca ttataaaaac
     2521 ctttccagat aagtatttca acataattat atcacactag tcaaaaccat aaggtatagt
     2581 ttaattaaca aactcttgta ctacgttaat ttagagtagt aaaccaatta tacaaaaatt
     2641 atttatttcc taaacaacta tataaaaagt ttgccccttt ttaaacaaaa agaaaaaccg
     2701 ctactcctaa gaatagcggt ttaatcatgt ttttaagcta ctaatgtagt tgctctatta
     2761 tttaagagta actgaagctc cagcttcttc caatttagct ttgatttctt cagcttctgc
     2821 agttgcaacg ccttctttaa caagtgctgg tgcaccgtca acaagttctt tagcctcttt
     2881 aagaccaaga ccagtgattt cacgtacaac tttgataacg ccaacttttt tgtcgcctgc
     2941 agatgtcaat tcaacgtcga atgaatcttt agcagcacca gcatcagctg catcagctgc
     3001 agcaacagct acaggagcag ctgcagttac accaaattct tcttcgatag cttttacaag
     3061 gtcgttcaat tcaaggattg aagcttcttt aatttcagca ataatgtttt caatgttcaa
     3121 tgccattgtt atttcctcca aataagtttt aaattttata atagtttttt tcgtagctag
     3181 gctacgctgt gtagcttaag attaagccgc gtcttctttg ctttctgcaa ccgctttgac
     3241 tgcaagagca acgttgcgca ctggcgcttg aagtacagaa aggagcatag aaagaagtcc
     3301 ttcgcggttt ggaagagttg caagtgcaag aatctcttct ttagatgcga cagcgccttc
     3361 gattgcacca cctttaattt caagtgcttc agcgttttta gaaaagtcgt tcaagatttt
     3421 cgctggtgcg ataacatctt cattagaaaa tgctactgca gatggtccaa caaatacaga
     3481 tgcaagatct tcaagaccag ctttttcagc tgcacgacgc aagattgagt ttttaataac
     3541 tttatactca acttcgcttc cacgaagctc acgacgaaga actgtatctt gctcaactgt
     3601 caaaccacga gcgtctacaa cgacgataga tgcagcagct ttcatttttt cagctactac
     3661 gtcaactagt tccgcttttt tagcaataat tgcttcactc attagtgtgt tcacctccgt
     3721 aattattttg cttggggaat ttttcaaaaa gaaaaacgcg cccaaaccta gacacgaaag
     3781 tacaatacgc ttctttttac atgatacgtt ttgtcctcgg taggatattt atgagtcgag
     3841 ctcccctact gtcttaggca gtttttttaa accgtatata agtatagcat agtcaaaaaa
     3901 agaatgcaag atttttgcaa acttttttta aaatttttcg taatttttct tttaaagttc
     3961 tactgtcagg acttgacctt gcttaacaac ctgttctccg gcgatataaa catcatctac
     4021 atcactagat ttaactgcat aaaccaggtg agacagcata ttttcctgag gttggagatg
     4081 aattttccct tgtggttgaa tgaccagaaa atctgcttgc ttgccgactt ccagacttcc
     4141 tatctgattt tccattccaa ggaccttagc cccttcgatt gtcagtacct tgagagctgt
     4201 ttcgattgga aactggctgg catccccact tttcatcttc tgaagaagag ctgcagtcct
     4261 tccttcctca aacatatcta gattgttatt ggaagcaacc gagtcagtcg caattccgac
     4321 tgctactccc gctttttgga gctggataat tggagcaatt cctgatgcca gtttgaggtt
     4381 actgatagga ttgtgggcga tagccacttg agaagatgcc aagcgttcaa tttctctctc
     4441 gtttaattcg accccgtgag caaatacgga cggatgatct aaataaccca gttcttcaag
     4501 aaaagcaagg gggcatttgc cgtatcgttt gaggataatt cctgactcct ccttggtctc
     4561 cgccacatgg acatggagcg gaatatttag ctcttttgcc atttccaaac tcgcttccag
     4621 caagtctcta ctgcagctat acggagaatg aggtgctacc ataaccttga aatttggatt
     4681 tttatatttt aagatttcat ctatgatgga tcgagttctg cttatagtct cagcagttgt
     4741 ttctgtctct gaagaaaaga gagtcggaga aaaataacaa cgcatcttgg aagttttcac
     4801 cacctgataa atttgctgga tatccacacc attgggatta tacatatcgt taaaggttgt
     4861 tgttcctgac tggagcatct ctgttagggc ttctttaacc gcattggtag tcatgtcggg
     4921 agtaaactca gattctgctg gccagatata gtcattgagc cattcatgga gattgctgtc
     4981 atctcggatc cctctcagac ctgtcattgc agaatgggtg tgacaattga ccaaaccagg
     5041 cataatccaa gctccctgat agtctataat ctgctcagct tgttctaaaa acgctggctt
     5101 atcttgaccg acatagacga tttgagaatc cttgactgct aagattccat caagataaac
     5161 atggaaattt tgatcacaag tcacgatatt tacatgctga aagactttca ttataggctc
     5221 cttttctaaa agacaagttg tactctcttc aaaccacttc agattcactt tgccgtaggt
     5281 gtggttactg acttcgtcag ttctatctgc aacctcaaaa cagtgttttg agctgacttc
     5341 gtcagttcta tctgcaacct caaaacagtg ttttgagctg acttcgtcag ttctatctgc
     5401 aacctcaaaa cagtgttttg agctgacttc gtcagtctta tctacaacct caaagctgtg
     5461 ctttgagcaa cctacggcta gcttcctagt ttgctctttg attttcattg agtattacag
     5521 tgaacaattt ttctagctat tgtaacaaaa aagtcactcg aaggcaactt ttttcgtcca
     5581 taaactttca aaagagaatg gcttattcag aactaaaagc cgcagctttt tgcatttggt
     5641 aatacttacc ctttctatcc atgagttctt gatggttacc atattcaaca atatcaccat
     5701 ctactaagac aagaattaaa tccgcatcct gaatggttga caaacggtga gcaatgatga
     5761 agcttgtgcg gcccttcatg agttttgcaa aggcatcctg taccagcact tctgtccgtg
     5821 tatcaatgga agaagttgcc tcgtctaaga taagaatctt tggaataacc agaaagactc
     5881 gggctatggt caagagctga gcttggccga cagagagaga ttctccagca ttttccaact
     5941 tggtatcgta tccctgtggc aactgttgga tgaaaaagtc tgcattagct gctttggcag
     6001 cagcaattac ttgctctcga ctggcttcag gattgccaaa ggcaatatta tcatgaatgg
     6061 tcccttgtgt gagccaggtt tcttgaagca ccataccaaa ctgctgtctc aatgatactc
     6121 gtgtataatc ataaatggat tgcccatcca gcaagatatc tcccgagcta atgggataaa
     6181 aacgcataag gagattgata agagttgatt ttccagcacc tgtcggacca acgatggcta
     6241 tcttactacc agctggaata tcgatagaca agtccttaat caaaattttt tcaggatggt
     6301 agccaaaaga gacatgttta aaggaaatag ctcccttaac ttggtcactg gtcaagactt
     6361 ccttacctgt ttcagccact tcagggctat ctaagactcc atagatacgc tctacgcaag
     6421 ccagagcact ttgcaactca gctagcactg aagaaatatc attaaagggc ttggtgtatt
     6481 gctgaacata gttcaaaaaa gtcactaaac gaccgacggt caaggttgaa cccatcatga
     6541 tacgataagc tcctactcca gctaaaaggg cataaatgag tgcatttaca aagcgagtcg
     6601 aaggattgac cgttgaagaa taaaagatgg ctgactgaga atagcctgag tagttgtcat
     6661 gagcctcacg caatctttgg ataaattctg tttgagcatt gaaggactgg attatagtct
     6721 gctggctaag cgattcttca atcaactgag tctgaattcc cctcgtctct gtttgcttct
     6781 ggaagagatg ataggatctc ttggcaataa agcgtgaaat caccatggac agtggcgtca
     6841 acagcaagac taagagagtc atgaggagat gaatttggag catggctaga atactaacca
     6901 aaatcatcaa aacaccaatg aaaaattggt taaaaatcat ggtcaagcca gctgccaact
     6961 gttcgatgtc cgtggttaca cgactaacca tctctccact accttgccta tctacaaaag
     7021 caatcggtaa acgatggagc ttatggatga ttcgctctcg caaatctcta gtataagaga
     7081 agattagacg attatagagg agaggattgg cccattgtac cagagtattt cctattacca
     7141 ccaagagcat ctggagaaaa atctgccaaa aaactggtga tgaaccagcc actaggactt
     7201 ggtcaatgac ctgcccaatc agaataggta ggtaaattga taagccaact tgggcaatag
     7261 ttcctagaaa ggctaggaaa aggaggaagg gatggtttgc taaatctacg gctaaacgtt
     7321 tgagcgtctg gtttacagtt tgtcgtttca ttctagtcct cctttccatg ttgggatgca
     7381 ttgatttcac gatagacttg gctggatttc atcaagtcat cgtgcttgcc aacagctagc
     7441 aactcacctt tttccaagag gagaatctgg tccgccatct gtaaagttga ggttcgttga
     7501 gagatcaaaa ttaagctcgt gtttggaaaa ttttctctaa tagctttcaa gagcttggac
     7561 tctgtaatgg tatccagtgc cgaggttgca tcatctagga tgataaacgg agcttggcgc
     7621 aagactgctc gggcgataga caacctttgt ttttgtccac ctgagaaatt tcgcccccct
     7681 gcctcaacta gggcatccaa aagtccttcc ttatcactga caaaatcctt agcttgcgca
     7741 atctccaagg cctgccagag tttctggtca gatacttctt gattgaaacc tagagtcaag
     7801 ttggaacgaa tggttccttt aaagagttcg accttttgag gtacataggc aatccaagac
     7861 cgccactgct ccaaattaag aggactacgt ccattttgat aaaggtcaat gttccccttg
     7921 tctactggat aaagtccaag taagagttgc accaagcttg atttaccaga accagtcccc
     7981 ccaatgatac caaggatttg tccttgagtc atatcaaagg aaatgtctct cagagaaggc
     8041 tgggccgcat caggataggt aaaagtcaat tcttggactt gtaaaacccg accactggta
     8101 acttgctttt gttctaattc tgaatggatg ttttcgggag attccgcaaa gacctcctcg
     8161 attctcttgg ctgagatata ggactggttg agggaattga tcagcatggc aagcttgacc
     8221 aattccacca aaatctgtaa gaggtaattg ataagagcaa tgagagcacc ttgactgagc
     8281 actcctcctt gaattgaaat atagccttgc cagataataa cgagaagagt tccattgaca
     8341 atcagatagg tcagaggtgt taataaacta gaccagaaac ctgtcttttc ttgtaatcta
     8401 gcataaactt ggttaagggt ttgaaaaatc tgtaactctc gtttttcttg accaaaagca
     8461 cgaataaccc gcatcccttg caattgctgg cgcgtttcct gaaccagttg gtccgttttc
     8521 tttctgagac tactgtagag aggattgacc aatcgagata gccctacaat gacaatggtc
     8581 aaaatggcaa ccatgactaa gaaccagaaa gtcaactcag ctgagattcg ataagccata
     8641 aaaatggcac caaaaacgat aatgggcgct cgcaaaaaga gacgcaggaa ttgattgata
     8701 ccagtctgaa tctggtaggt atccgaagtc aagcgagtga ccaaactaga agttgtcaga
     8761 cggtctctgc tgtccttgga caaggaaaga atatgacgat aaagatcgtt tgtcaattcc
     8821 ttagcaaagc ctactgctgc ctttgctgag taaaattgag ctatcaaggc cactaaaacg
     8881 ccaattactg caaagataag gagcaggcca atctgcatcc agagatgacc ttgatctccc
     8941 tgaggtaaag attggtcaac aatcccagca atcaccatgg gaaccaagag ctcaaaaaca
     9001 gcttctaaca gcttgaacaa gggggctaaa attgattcct tgatgtaggg tttgaagtaa
     9061 gataataggt gtttcataaa tcccttctat tcatattcta gaaatgaaga aagtgggaag
     9121 ccccactctc tgttttattt gtttaagtaa ggcaatagat agccatatcc tgctttttcc
     9181 atctcatcct tggccacaaa gcgtaaagaa gcagaattga tacagtaacg gaggccgcct
     9241 aactcccgcg gtccatctgt gaaaacatga cccaagtgag cactgcctga acgagaacga
     9301 acttcaattc gctccattcc atggctcaga tccttgtaat aatgaatcaa ctctttggaa
     9361 atcggacggc taaaacttgg ccaaccacaa cctgaagcaa acttatcctt ggcaaaaaag
     9421 agtggctcac ctgtcgtaat atctacataa atcccctctt caaaggtttg gtcataggca
     9481 ttggtaaatg gagcctctgt agcagcttct tgtgtgacac gataagactc ttcagataga
     9541 ctggccttca acacctcttg actaggcttt tcatagtttg ctgcatcaat caatggctta
     9601 tcagcatcgg tcacatcgat atgacagtaa cctgaaggat tcttcctgag atagtcttgg
     9661 tggtagtctt cagccagaat gtagtggcgt aattgctcca cttctactgc aatctttcga
     9721 cccagcatgc gttcctgctc ctgtaccact gtgtagatag ctggcaaatc tgcttcatcc
     9781 tgataataaa tcccagttcg atattggcga ccacggtcat tcccttgttg attgatagat
     9841 agaggatcga taactcggaa ataataaagt aaaatctctc tgagtgacac ttccttctca
     9901 tcgtaaatca cttggaccgt ttctgcatgg tctgtttcct tgatcaactg gtaattggtc
     9961 gtttcgactt gaccattagc gtagccaaca ctggtttcta gcactccaga aatgcgtgaa
    10021 aaatattcct ctaggcccca aaaacaacca cctgctagat aaatttctgc catctttatt
    10081 tctcctttat cacgttttta actaatactc ttcgaaaatc tcttcaaacc acgtcagcgt
    10141 caccttaccg tatatatgtt actgacttcg tcagttctat ctgcaacctc aaaacagtgt
    10201 cttgagctga cttcttcagt tctatccaca acctcaaaac actgttttga gcagcctgcg
    10261 gctagcttcc tagtttgctc tttgattttc attgagtata aacttctttt cacaaaaagg
    10321 atatgaaacc ctctggtcaa gagtttcccc atcctatctt ctattcttta ttttgcttct
    10381 acacggacac cttgggtatc aactctcaag tcatgcagtt ttcctttgaa aggttgcttt
    10441 tccaattctg ccttaattgt tggcatcttg tcatgagaag ccagaaccat aactgtcggc
    10501 ccagcaccag aaaggtaggt tgcataggcc ccattttctt tggtcacttg cttaatcatc
    10561 gcaaattctc ttaccaagtc ctgacgatag cgctcatgga agaggtctcc ctcgattgct
    10621 tgcccagcgg tcaccatgtc tcctgccaac aaggcagcaa ccgctacatt ggcgatagaa
    10681 cttgcagcag cagcttcctt ataagacaat tttttaggca agacactacg gctgtcgcga
    10741 gtacgtaatt catagtttgg aatgtaagct agaaaatcac actctggaaa gtctgctacg
    10801 atagcagaga cttgcccttc aacagaactt gcaataacga gattaccata aatggctgga
    10861 gccacattgt caggatgccc ttcaatcttg gtcgctaact gcaatttttc atggtctgat
    10921 aagttgagtt gacccagttg gttggctagt tcaatcccag caacgataac cgagctggaa
    10981 gaacccaaac cgcgcgccaa agggacatca ctggtcattt tcaagcgtct tggttgcaag
    11041 tctggtacaa tttgcaaagc gattttgagc aagagattac gctcatcatg tggaatccat
    11101 ttgccaatct ggtgttcaat cagccactca tctcgttctt cgcagacctc aatttgaaga
    11161 tacttggtta cagctacacc gaccgagtca aaacctggcc cgatattggc actggttgca
    11221 ggtacaataa tcttcatctt attctcctag caccttgaag gtattcaaga ggtcgaattc
    11281 tgaaaccttc ttcaattcag ctgagacatt ttcaagctgg gctttattaa tcttgtgtgt
    11341 gatgataacg acacgcgcct tgtcaccctc tttgccatct tgaaggattt gcttaaagga
    11401 aatatcttga gcattgaaga tttcagccaa cttcaagacc tgaccttttg agtctggagc
    11461 caagattgag aaatagtagt ttgctttgac atcttcagga tttgccaaga ccaagtcacg
    11521 gctatattcg ttgaagtctt tgccaatggt accatcattc aaacgacgaa cgatacggac
    11581 aatatcagct acaacacttg ttgcagttgg tttttgaccc gcacctggtc cgtagtacat
    11641 agactcacca ataccgatag attctacaaa gacagcgttc attacgccat tcacactagc
    11701 aagtgggtgc gctttcggta ggaaggttgg agtcacttct gcagcaatac ctgaagaagt
    11761 ttcctcaata gaaccaacca atttcactac gtaaccaagc tcttgagcta cagctacgtc
    11821 ttctggtgtg atattgcgga ttcccttgtg ggctacatca tcaaaggcaa tcttcatgcc
    11881 aaaggcaaat tggctcaaaa taaccatctt gtaggctgca tcaatcccat ctacgtcatt
    11941 cgtcggatcg ctttctgcaa atcctagacg ttgtgcttcc gcaagagcat catcgtaaga
    12001 ccagccttct tccaccatct tggtcaccat gaagttggaa gttccgttga ctactccaag
    12061 cacgcgcgta attttatcag aagccaagga atttgctaaa gtacgaagaa ttggaatccc
    12121 accagcaact gctgcttcgt agtaaagtgc taccttgtta gcttgagcga tttctagcaa
    12181 ttctgcgcca tggacagcta aaaggtcctt gttagcagta acaacgtgtt ttccagcttc
    12241 caaggcacga gtgataaagg ttttagcagg ctcaatacgc cccatcaatt ccactacgat
    12301 agtaatatcc tggtctgata aaatatcatc cacattggtt acaaagttaa agtcattccc
    12361 tgctgcaagc aagcgatttt tttcatcttc atccttgacc aataccttag caactttgat
    12421 atctgaatgt gctgattgat tgatttttcc tccattttcc tttaggagga aaggcacacc
    12481 acttgcaacg gtaccaaatc ctagtaaagc aattttaact gtcatcttta tctcctcgaa
    12541 attttctaat atagccatta taacagaatt ttgtgaaaat tcctattata gtaaatcact
    12601 atttcagtat aaaaagaaaa aacgaatcag acgattcgct cttcttaaaa tctgaaaata
    12661 gctttccaga aaggattagc cgattttttg cagattgagc actgcatcgt gactcatcaa
    12721 gacttgacca tactcttgta agactgagcg actgatatca ctatcgtctg caaactcgcg
    12781 catacgggcc aacagccaag ctggatatgg gcttggatga ttttcaatat ccactaaaat
    12841 ggtcaaataa tagcgctcgt tcattttgta gagttcagaa gtttccattt caaaagtcac
    12901 tgtcttggca aaagctacca agtcagccaa cttagcaaaa gaaaggatgt agtagatgta
    12961 aggttctttc ttactctcag cttcttgttc agcctgctct tgctcttctt ccttggcttc
    13021 aacttgctca agagattgaa tggcttcgat atcatccttg gttttgtctg cgatgctttt
    13081 ttccagggtt ttgataaatt catctggaga catttgagcc aattcttcca tatctggcaa
    13141 atccgataag tcttcaaaat ctagattttg gtcaatcttt gacttggtca caaagacatc
    13201 taccttatca ggttttggag tcacacggaa gctcaacatg cctgtatcca gaaagctatc
    13261 aggcatctct agctcatcca agatagcata aaagaactct tctgtttttt cttgaggaac
    13321 gagaaagtca gcaatctcca ttccacgatc catcaaatcc tctaaagaca tcgtgatttt
    13381 taaagttgta tcactaattt gtttcatttt cattgctagt aacctcatac tttcagttct
    13441 atctattata ctagattttt acgattttat caaaagaagg ctcctctata cggatagatt
    13501 ttccctaggg tctttctata ggagactcca agagaaaatt tctgcagaca gatagaaaaa
    13561 gccttcaaaa tcggctctta gccgattttg aagaccttat acatcagaat acttataatt
    13621 taaaggttgc tacaccgagg atagaacgat ttaagtttct gagaatttga agactttgct
    13681 caaatttctt ataacgagtc actccgtact cttcaacaag aaggactgta tctctttcca
    13741 aaagagatga tacatcctgc aaatctacaa aatgcattcc ttttaaagct tcttgactct
    13801 gtttcaattt atctaggata gctttatttg agctaacgat ggtcaattcc tgtccagtat
    13861 ttttgtatga caaaacatct gctaggttag caattgttgt aatctctgtt acaaaatcaa
    13921 tttgatactg agaaaaatca cctactctat tgattgttgg attaaagaga taaactaaca
    13981 catttcccat cacaaccaaa atcacacaaa ccactccaat aacaactaaa cgaagaatca
    14041 gatttttcac atttaagcca agcgctgttt caccatttgc gttcaattct ttagagttga
    14101 tggtttccag tttttcaatt ttcacatttg cataagcatg tttaaatttc tcaatcaacc
    14161 catcaatttt tttctctaac aagtcattgg catctttact tgatgtcaaa attttcacac
    14221 caacccctgc atcgtcaatc atatagtaga cggtcaattt tttccaccaa tagtcattcg
    14281 ttgaattttt caaggttgtt tccgtcgtgt ctaattcact ggcaattttt ttcaactcac
    14341 tgggttctac atcattgaaa agataagctc cattcaaatt accatcaatc aatttcccat
    14401 aaaaatcact ataaccacca atttgatgat tcaaaatcgt tttggccgaa tcttctggag
    14461 gagtgatttt atagataaga taagttgaat aacttgttgt atctttgaca gtgtttttat
    14521 tcctaactgc tttaattgta aatggtacag caatgagagc aaataaagcg atgagagcta
    14581 aaatatttgc ttttcgtttt ttataaagat ttgcaaacaa atcagctact gaataatgtt
    14641 caaacatgat ttttttctcc tttgtttagt agatactagt tttcctttgt aagcattttt
    14701 gctacaaata taatcacaag aacaattccc cagaattgca ttgtaaataa attgaagaaa
    14761 ctttctgaaa agctgcttct tggcataaag aatagattat tcaagatgag tagggataaa
    14821 gcaaatagga ttgtccttga gcgataggct acttgcagca tggctataaa taatacgccg
    14881 agtaagaaac taagcagaaa gactccaatc ataccatagt cggtatacaa ctccatgata
    14941 taactacttc cgataccatg ccctttcaag tattccttgt tcaagacaag ataggataga
    15001 ttgtgggcat aactattact atcaatagct agttccacac tattggttgt atgttcaaag
    15061 gcttttcctc cgaaaatggc tcccaaactc ccccttgcaa aataatcaag aacaggacca
    15121 aaagtaaaat tacggaaatc tcggtaaggg aggctactgt taaatagaaa acctcgagcc
    15181 agaacaccaa aactagtccc ttgtttatag ataaagtcaa gtaagatatc ccagaaacct
    15241 gtatgagaaa cttggacatt atcccgtaca taattgagta ctcccatcgc taacatgaga
    15301 ataggagaac ctacaaaaat cgctaacttt tctttaaacc caatccattt tcctttttca
    15361 gtttgctccc gcataaagta ataaacaaaa gcaaataaaa tacttaaaat aaagggattt
    15421 cgtgtcccaa ttgccaaatg aatagtatta gctgcaataa aggagacaag cactgctgtg
    15481 gcctgcaatt tctttggctt ggttgccaga tacatacaca ttgcatagac cgtaaaggta
    15541 gacaaaatgt aggtaaaata aggcagttta ctttcaaaat ttgcatagta ggcatagtag
    15601 gaagtctgca aacgatacaa gagccgttca aataaccgaa tgaaatagaa aggataggtt
    15661 agaagaaaaa ctcctagtga tacaaagcgt aaccgcttga tataaacctc ttttagagaa
    15721 tttcctatat ttgctacttt tattttcttc ctagctatga agtaacgagc cagaatgcct
    15781 cctgtggtca agcccagaat cgaaaccatg acaactataa aggcaaaacg ataggctatt
    15841 ggatgatagg tatccaaagc accatcccta aaataatcaa tggtcggtct tgataccaga
    15901 aatacaaaaa tggttaaata gaaaataaaa tggattaagt aatacttgat atcattccaa
    15961 caagcaatta agctactaac caacaagaac aataaagtag aaagtaagct aacattatta
    16021 ttattattaa acagatacac aattccactt actagcgtca aggcataact gactatggtc
    16081 aaactaaata ataatcgttt cccatcaatc acttggtcac ccccgttcta atgtaatttt
    16141 ttagattttt caatattttt cagtaataag aatcgatata aggaaatatt tatgaatagg
    16201 gccaaagcac taattcttct ccccttacgg aaaattggat tcctagaaat agcaaaggca
    16261 tggcctttta aaaaacgatg aatctgagaa taggcttcaa actgtttata ctgatcatct
    16321 agcaacatct tatccagaat aaagaagtgg gcataggcca atctgaaaaa agcgacctct
    16381 ttcaagtcag gatagttttt cacaacttca ttataaaact tttggtagat atcaatatag
    16441 gctaaatcct tctctgcata gggtttggtc gtaatactat cccctctatg gaaatagtaa
    16501 taatagggtt tagtattaac cacatacttc ttggccaact tgattaaatc aaaatggtaa
    16561 taggcatctt cgtaaatcaa ccccttagga aaggataggg cagttgcaat ctgtctcttg
    16621 attagcttat tgcaaatcgt cccaggtatt ttttcaccta tgaggtattc ctttagaaat
    16681 gtttgagaat cacagacaaa atagtcatcc tgattggctg actgtgggct ttcatcatta
    16741 gcatagacat tcatgacacc acagcttgaa acatccgcat cttcttgaac taattgctca
    16801 tataagctct gaatcatttc tggatggata taatcatctg agtcaataaa aatcagataa
    16861 tccccgtgag cctgcttcat cccatcattt cgtgcttgcg acaatccttc gttcttttta
    16921 tgaagcactg acaccctgtc atcttgttca gcgattgaat cacacaagcg accactttca
    16981 tctgttgcac catcatcaac aagaataatt tccagatttt gataggtctg cttctgaatg
    17041 gaagctatcg atttttctag gtactgcgcc acattataga ctggcacaat cacactaatt
    17101 aatgcagttt ccatgctact cctctaatag tttttctact tgttcgattt gttttgtaat
    17161 tgtaaattgt tgaatgaatt ggctagcctc atcgacatca aagtttgagg cagaagtcat
    17221 gtaattagta atcgcctgag ctgcctcttg attgctctca atgatttgtc caaatcgtcc
    17281 ttcttgggat aattcctcag cccctccaac gtccgtagag ataaaaggga gtcccagact
    17341 caaggcctcc acatacactc caggaaaacc ttcttgttta gacatagaca agagaacttt
    17401 cgtctgagat agatactgat aaggattttt ttgataacca aggaaatgta catagtcctc
    17461 aatcccatac tctttgactc gttttttcag ttcctcttcc atatcaccag ccccgataaa
    17521 atagagatga tagttttttc cctcttggtg taataatcgt atcacttcca ctacacggtc
    17581 agaaccctta ttttcctcaa tccgtccgat agtacagata ctttgaggag caatctcgat
    17641 atcgatcttc tcttgagatt tttctagaat agtctgaaaa tcatatccat tgtagattgt
    17701 ctgtaattta gaagcataat ctggataaac ttccttgata gaattgctgg tcttttttga
    17761 aatccctaca attgtattcg cagcatccaa ctggcttcta tgtgattctc ttttagagct
    17821 atccttaaga agttcttcaa tacttccatg aatccaagat atcttcttga cttctcttct
    17881 tttagagaac aacagtggtg gattcataat ggtaaaagaa acttcaacat cataatcatc
    17941 ttttacaagc aaacgacgag ccagtcttgg aaaataaatt ctcattctcc acaaaaaagc
    18001 tcgtaaccat ctggtttggc gataatcttg aagggatttt aaaatgcgta catgctttgg
    18061 aacagattca tatcccttgt caaagtgctc catttcaaga atatcaatat catacttttc
    18121 tagatccaga tttgaaacaa tggttgatag aatcttctct gcaccacctc caagagaaaa
    18181 agaccacata aaaaataaga tttttttctt agccaccata ttctcccttg tattctgtat
    18241 aagacttatc catatcagcg atgacagcat catgatgcgg tacctgcttg tctgctggtg
    18301 gaggcgtcat ataatcccca aaagcagttc tgagatagac atcatagccg attggaatag
    18361 gcatctctgt tccttcaaat ggcaagaaaa gattgtcttc aaaagatgtg attgggtact
    18421 tgtttctcat gtagccagga cctgagcata attctgtaat gccatcacaa tcagccaaat
    18481 catacttagt catttctttc tcagcttttt tccagatgcg ataacggaga gattttggag
    18541 tcaaacccag taaaatgcga cttccccatt tcatgagagc accatgcttt tctggaatag
    18601 tttgcgcaca aaagagtgaa taaatcaagg cccaacgaac ctgttttttc cgctcagctg
    18661 gatctttcgg ataataatcc aaaggcaaaa catccaaggc cagaccatgt ggcaaatcca
    18721 aatcctgctg ataaggcttg atacaggtgg tttccttgtc acgaatggta ataaaaagat
    18781 tacgatcaac aaaatccttg taactctttg acaagaaata acgttcatct gcataacgag
    18841 gccataattc tgctaatttc tcataatctt tacgaggcat aaaaaagtct aggtcgtcgt
    18901 cccaaggaat aaatcccttg tttcgaaggg taccaatagc gcctccgcca cagagataac
    18961 agagcaaatc atgttcttta caaaaggcca caaaatagtc agccatctcc agactacgag
    19021 cctgaattgc ttttaaatca gtcatattgt tcattattct ttctatcgta tcgtttcatt
    19081 ataccacaaa caaggggtga aaatctattg cagactgtaa aaaatcaaag cctgactgct
    19141 atccaaatag ctatcaaact ttgatttttc tgtcttatac tcttcgaaaa tctcttcaaa
    19201 ccacgtcagc ttcaccttgc cgtaggtata ggtaactgac ttcgtcagtc ttatctacaa
    19261 cctcaaaact gtgtttttag cagcctgcgg ctagcttcct agtttgcact ttaattttca
    19321 ttgagtatta tcttatctca agcccatttg agcgagcttg gtttgatatt tgttttgatc
    19381 aaccagcaag cccaagcctc cataaacatc ataggcatct acccagtcac ccagttctgg
    19441 aatcgtcaat ttttcaatac cattttttgc tccatccaaa acagataaac cgtttgttag
    19501 gaggaaagta tagggtacgt tggttgaggt catagcaaaa acctttccaa gagcttcaga
    19561 accagtgaaa agtttagtgg gatctttaat ttgctctaaa attgctgtta aaacttgttg
    19621 ctgtcttttt gtacggccgt aatccgcctc atcatcatca cggaaacgag cataattgag
    19681 cagggtcgag ccattcatct gctgttttcc gactttaatg gtttgggttg gagactcagt
    19741 ctcggtagca tataaatcat ctccgactgt agcttctgtt aggggacgcc cattcaatgt
    19801 tgaaaattga gcatcaatcg tcaccccatc agggaaaagc gtgtcaatcg ctgtggcaaa
    19861 ggcctggaaa tcaaccaagg cgtagtactt aatgtccaag tcaaaattat ctttcaagac
    19921 ttggcgaacc atttctgccc ctttttgccc ctcttgttct cctaactcgt aggctacgtt
    19981 taacttgtta tctgtctgtt ttctaccatt aatcacttga ctataaccat ctatatagac
    20041 caaattatca cgcatgaaac tgactagctt cattttctta tctgagcccc cgacatttaa
    20101 taccataata gagtcagttc gtgtctcaac actgttctgg ccgattcgac catcagtacc
    20161 catgattaaa atattaactc catctctagt gtcctgacca ttaaatactt ctacttgagc
    20221 tgcccgggca tcagcagttt tctttgcgct agcatcttgg taaccacgca aaaacatgaa
    20281 taccatggcc aaagccacac agaccaaaag tgaaaaaatc accataaaaa ttcgtttaag
    20341 acggagcttc cgtcttttct tttttggagg gaaagagagt gcttgtgatt tggattgtga
    20401 gcgactccgg ttcgcatagc ttggtaagtc aacctgctct tctctttctt gttccaagct
    20461 agagctacta tttcccctag caagagttag cttttcttgc aaataggcaa actcattttt
    20521 ttctctctca ttgagatagt gaatattttt tagcaaataa tcataacgca actgctcatg
    20581 atgacttaag ggattttctt tactcatctt ctctcctttc catggtctga tattggataa
    20641 ataggatagg cacccagaat tttatactgg attccaatcg cttctaattc tttttgggca
    20701 aagtggacca agtccttatc ggtataatcc acatcgataa tgaaaaagta ttcacccagt
    20761 gctgtcttga gtggacgact ttcaattttt gtcaagtcaa ttcctcgcca agcaaaggtc
    20821 gacagggctt tataaagtgc acctggaagg ttgtcaggta gggtcaaggc taaactcatt
    20881 ttttcagttt gtgattgcaa gggaatagtt acaccttcag ctcccaaaac ccaaaaacgt
    20941 gtgaaattgg cttccatttc ctgaatatcc tcggcaatca gttccaatcc atattcttca
    21001 gcagaacttc taggtgcaac tgctgcaaag ggctgatctg gatgttcgga aataaaacgg
    21061 gccgcataag ctgtactagc tgttacctcg atttgagcct ctggatattg ttcatcgatg
    21121 aatttctttc cttgagccaa ggcctgtgga tgtgaaaaaa tcttttcaat cttagtatgg
    21181 cctggaacca ccatcaactg ctgatgaata ggctgaacga tttctgctac tgcttggatg
    21241 tgagcctgat gaaaaagata gtccaaggtt tcatgaacac taccctcaat agaattttca
    21301 actggcacca cagaatagtt cactaatcct tgctcataag ccttgatgac atctgtaatg
    21361 ttggcaaaag cctgcaattc ctcatgagga aaagctgtct gcacaacgtg gtgtgaaaat
    21421 gatcccttgg gacctagata agctattttc atcttagttc ctctataatt tcctctgggc
    21481 ttagcttggt cacatccaaa acccgactag ccacttcctc ataccaagcc tgtctttctt
    21541 gaaaaatagc tactagttct tccttgctat tatttagaaa aagcggtcgc tgattgtcct
    21601 tatcagctgc gatacgtagg tagagggttt caaaatctgc tttcaggtag atgttatctg
    21661 tattagtctt gagtaagtca cgatttctct gagaaataac cactcctcct ccagttgaca
    21721 cgacttggtc tgtttgtagt aaatcagcta ggacttctga ttctacctga cgaaaggctg
    21781 cttctccctt ttcagcgaaa aaattcgcaa tggacatacc taggcgcttc tcaatcagag
    21841 catccatatc aaggtaatta gggtccaagc ctcttgcaat agtcgatttt ccagccccca
    21901 taaaccctaa taacacctta gccatgaatc aagctctcca aatcatcaaa gaaactagga
    21961 tagctggtat tgatggcttc tgcacggtca agctccacct ctccatctgc aaccaagagg
    22021 gctgcgatag ctgtcatcat gccgatacgg tggtcaccaa acgtattgac tctagcaccg
    22081 tgaagagctg atttcccttt gataatcatc ccatctgccg taggagtaat atctgctccc
    22141 atactattta aggcgtctgc cacaacctga atacggtctg tttccttgac cttgagctcc
    22201 tcagcatcct tgataactgt tacaccttgg gcttgagtcg caagcagggc aataatgggc
    22261 aattcatcaa tcaatcgtgg aatcaaagcg ccaccaatct ctgttccttt caagtcagaa
    22321 gactcaacaa tcaaggtagc agatttagcg actggatcga tttcagttat ttccaatttt
    22381 ccacccatgg cacgaatgac atcaataata ccggtgcgag tttcgttgat ccccacattc
    22441 tgcagcacta aacgagaatt tgggacaatc aaacctgcga ctaaccaaaa ggatgcactg
    22501 gaaatatctc ctggtacgac caccttttgt ccagtcagtt tttgaggtcc ttgaactgtg
    22561 attttcttgc catccacact taaatggcca ccaaattgtt gcaacatatc ttcagtatga
    22621 ttacgggtgc actctttttc gataataact gactccccct tagcttgtaa ggctgcaaac
    22681 atcaaggctg acttgacttg ggcagaggca attggcaact cataatgaat aggtcttagg
    22741 tttttcgtcc cttttaagcg aaggggaggc aagtctcgtt cagtttgccc tgagatgctg
    22801 acgcccattt ttttcagtgg aagggtcaca cggtccatag gacgtttgga aagactatca
    22861 tctccaaaca tctctacttc gaaatctgca ccagcaagga cacctgaaat caggcgaatc
    22921 gaggtgccag aatttcccat attaagggca ttttgcggcg cttttaagcc agccatgcct
    22981 acaccttgaa tggtaataac cccatcttta tcctcaattt caacaccaag gtcacgaaaa
    23041 acctgcatgg tcgaaagaac gtcttcacct cgcagaatat cataaacctt ggtctcaccc
    23101 tcagccaaac ttccaaagat aatggaacgg tggctgatag acttgtcacc tgggacgcgg
    23161 atactaccat gtaaatggcg aatatttgtt tttagtttca tactggacct catacttgca
    23221 atacttttac ctattttatc ataaaaagcc agaaattcct taaaaattcc tgactttagg
    23281 atagttcttt tcttatttca gcaattctga aactggttcg aaaacaattt tttcaatgtc
    23341 agaaaggtaa atggccaatt gttgttgctt ggtaaagaat tctgacaaga ggctatttcc
    23401 ttgaatctgt ttaccaaagc cttccatctt agcttggaag gacgcatctg gcatttgacc
    23461 tgtctgtgct agtttttgaa tttcctcttg aaaggcaaga tattctgtaa agattttgct
    23521 tgcctcagca tctgctgcaa tcgcatcttt agctgcttta acagccttgt attctggtaa
    23581 tccgcgtaga ccgcgactga gttcgtttgc actatcgtaa atatttgaca tgttcttctc
    23641 cttatttaat gacgactgta tagtcggtat tttttgttat gagatgctcg gctctttcca
    23701 agtcttgagc atttttaaat gaaatttgta ggattccgtg aatatcctca cgattttcct
    23761 cgttgatgtg gatgttaacc aaggaagtcc cacgtagcag ttccaaaatc cgcaggatga
    23821 catcttcttc atcaggaacg tcaacataga ggtcgtaaga gctatccaca ccaccacgct
    23881 tatggatttc catggtctgg cgttgttcac gcgcttggtt aaaaaagttc caaatttgct
    23941 cttcatctcc cttactaatg gcctgaccaa tcgattccaa acgttccttg aaatcctcaa
    24001 ttctatccag aatggtctcg ctattggaca agagaatgga ggtccacatt cctggctcgc
    24061 tttccgcaat tcgggtcata tctcgaaaac cacctgccgc aaagcgcctt gccatctcat
    24121 gctcttgagc atagaccgca gtctgctcca tgagactaga agccaaaata tgaggaaaat
    24181 ggctaatctg agaagtgaca cgatcatgct ccttggcatc aatctcgata aaacgagcat
    24241 gaagacctga aagcagatcc ttcatttcct taagcgtgtc ctgacttgtc aggcttgaag
    24301 gtgtaaagat ataataggca ttttcaaaaa gattgacatc tgccgaagca gcccctgtct
    24361 tgtgactacc agccatggga tgggccccga caaagcgaac agacttgcca gccaaatact
    24421 gctccgccgc atccacaatg gttgacttgg tcgaaccagc atctgaaata ataacgcctt
    24481 ctcgcaaatc caaattggcc aactccttaa tgaaagcaat agtttgtttg attggcaagc
    24541 tgaggataat gacatctgcc aaaggagcaa aactagcaaa atcatccgtt gcacggtcaa
    24601 tcatgccttc tttcaaggcg atatctctcg aagcttgact acgattataa cctaaaattt
    24661 cataatctgg atgatcgcgt ttgataccaa gtgccataga ggctccaatc aacccaagac
    24721 ctgcgatata gattgttttt gccataggaa ctccttaata gttctttgta tagtctcggt
    24781 gtttggctac cgcttctttt agttcctcaa gattatctga tgagaatttt tcgaggatct
    24841 cttgcgccag aaccgttgct acaactgctt ccatgaccat tcctgcagct ggaagagcag
    24901 tcggatcact tctctccacg gttgccttgt aaggttcgtg ggtttcgata tccacactca
    24961 taagaggttt ataaagagta ggaatgggtt tcatgacccc acgaacaacg atgggttgcc
    25021 cattagtcat accaccttca aaaccaccta gattattggt acggcgagta taaccgtctt
    25081 ctttagacca gagaatttca tccataactt ggctgccttt acgataacca gcctcaaagc
    25141 caagaccaaa ttccacccct ttaaaggcat tgatagagac aacagcttga gccaatcttg
    25201 catccaattt tctatcccat tggacatagg aaccaagacc aactggaact cctccgacga
    25261 ctgtctccac aaccccaccg atggtatcac catcacgttt gatttggtca atatagtcct
    25321 tgatttcctg ttctcgttct tggttgacaa tagaaacttc agactgggca gctctttgct
    25381 taatttcagc gactgtcaga ttttcaggaa catctatttc cttaccacca aagaccacga
    25441 catggttggc aatctccata tccagctcag ccaagaggcg tttggctact gcaccaactg
    25501 ccacccgcat ggtggtttca cgagctgatg aacgctccaa agaatttcgc aaatcatcaa
    25561 aacggtactt aatcccccca accaaatcgg catgacctgg gcgaggatga gtaattttcc
    25621 gcttgctttt aaggcggtct tcaatgtcct ccgcagacat gatgtccagc catttctggt
    25681 ggtccttatt gatgacatcc atagtaatag gcgcccctgt cgtcttcccg tggcgaacac
    25741 ccgaagtaaa gacaacctgg tcactctcaa tcttcatacg accaccacga ccgtagccac
    25801 cctgacggcg tctaagatcc tcattgatat cctcagctgt caatggaagt ccagctggaa
    25861 ttccctcaat aatagctgtt agacgggggc cgtgtgattc tcctgcagtt aaatatctca
    25921 tacactctcc ttattttacc aagtagtctt tcatctcttc cagagaaact gggtgaatgg
    25981 tcgctgaacc aagctctggc accaagacca atttcaaggt gttaccacgc gctttcttgt
    26041 catgagtaag agcctgataa agcttgtcaa ctttccaatt ttcatagtca acaggcaagc
    26101 cgaatttctg acacatctct gtgatagatt gggtaatgcc agctggcatg aggccttttt
    26161 cctcagcaac cttggaaatc tgtaccattc ccatggcaac agcctctcca tgcatgacct
    26221 tgccataacc ggcagtcgct tcgatggcat ggccaatagt gtggccaaaa ttgaggtaaa
    26281 gacgaatacc attgtccaac tcatcttcaa ccaccatctt gcgcttcacc tgacaagaat
    26341 gttcaatcaa ggtctctgca tgttccaaaa tactctcaac agaaccattc agtcccgtca
    26401 agagagccca cagttctgga tcctcaatca agccatactt gataacttca cccatccctt
    26461 caatcaactc tctttttccg agggtttcaa gaacaagtgg atcaatcaga accccatctg
    26521 gttgggcaaa ggtccccacc atatttttag caaatggtgt gttaacgcct gtctttccac
    26581 cgatagaaga atcaacctga gctgtcaaac tagtcggaat ctgaacaaag tgaatacccc
    26641 gcatataggt agaggctaca aatccagcca ggtccccaac aacgccacca ccaagagcaa
    26701 cgattccatc gctacgagtc agaccttgct tgactagaaa ttcatagact ttctgaacag
    26761 tagttaaatt ctttctttct tcaccttcta agaaatcaaa aacagctacc tgaaaaccag
    26821 catcttctag gctgagcttg accttctctg catagagaga ggctacatgg ttatctgtca
    26881 caatgactac cttttgcggt tgccagagtt ctcgcaacca ctgaccagcc tgggccatac
    26941 aacctttttc aatctgaata tcataaggat gatgaggaat atcgattctg attttcatag
    27001 gagagtctcc ctttctttat tggtattttt ctgttaaaga ctgccaaatc tcttctgtcg
    27061 gcatttcctt gcctgtccac agttgaaaag cttctgcagc ttgatagagc aacattccca
    27121 gaccattgac tgctggattg ccctgacttc tagcccattt caaaaacggt gtttcaaagg
    27181 gttggtatat gatatctgca actaagagag tttctggtaa gactatgttt tcaggaacag
    27241 gagaggattg gccatccatg cccacactgg tggcattaac tagcaaatcc gactcggcaa
    27301 tccttgcttg cagttcagaa acatattcta aagcacacaa atccacttta aaacctgtct
    27361 gctcctgtaa cttgtctagg taaggtcttg ttttttccat agaaacggaa cgaacaaaga
    27421 ccgaaatctg actgacgcca tccaaaatag cctgtgccaa gattgattta gccgcaccac
    27481 ctgcacccag cagggtcatc tttttacctg aaattgtaaa agaaggcaag cacttaaaaa
    27541 atcccttgcc atctgtatta tatccaatta aattgccatt ctcattgaca accgtattaa
    27601 ccgcaccaat caagtgcgct tcatcgctca gcttatccaa ataaggaatc acctgctcct
    27661 tatagggcat ggacagattg atgccaaaca tctggtagcg acgaatattg gccactgttt
    27721 ctgccaagtc actcgcttca atctcccaag ccacataagc accgttggta gctgtcgcct
    27781 caaaggctct attgtggatg aagggagaaa tagaatgctt aataggattg gcaacaactg
    27841 cagctaaacg tgtatagcca tcaagcttca tccaaaatct ccctgatttt tttcatgcta
    27901 gctagagaaa tctgcccagg ggcactaacc tcatccagac tggcaaaaga ccaactcgaa
    27961 ccagtcacat ccgcagtgat acgagagacc ttgcccacct tacccataga aatggtcaca
    28021 tattcctgtt caggattgag ggttttaaag cctcgtgtat agttcatcaa gtctaagaca
    28081 tcctgctccg tgtgagccat caccgcaacc ttaacaagtt ttggatttag gatcgtcaac
    28141 tctgacaaga tttccatcat gttctcaggt gtttcttgga aattatggta actcaaaaca
    28201 agatttggga agtccagcat ttcctcaaaa acatccttgt agctatagta ctcaaaatca
    28261 atatagtctg gttgatagag ttgcgcaact tccttgatta gatggatata ctcttctgga
    28321 gaaaggtcga tttctccacc ttcggagcga gttcgtagcg tgaaaaccaa ctcacggcct
    28381 gcgaattttt caaaaatggc tggagctacc tgcaaaatcg cttctttagg cagatagtcg
    28441 gcacgccatt caatgatgtc ggcatccagg tacctcgtgg catccagagc ctgagcctcc
    28501 tctaaacttc ttggcattac tgaaacgatt aatttcattt actaaccttc atactaatca
    28561 ccttgaggta attactactt tcatcttttt tattataggc aaaatctgct ggaagaccat
    28621 atttgtttaa aatctggtaa cttcttcctg caaaaccttt atcaatttgt tctgtaaatt
    28681 tctgacggga aacattggca gcattggtac tggcaatgat aatccctccc ggatttaaaa
    28741 tctcaagact ctgggaaatc aacttgtgat aatccttggc cacagagaaa gtttgttttt
    28801 tattccgagc aaagctaggc ggatctagga caatcacatc gtaggtcaag tctttgcgtt
    28861 tggcatattt gaaatactca aagacatcca tgactataaa acgatgctcg tctgtgctga
    28921 gcccatttgc ctgaaaatgc gcttgagaca attctcgtga acgtttggct agatcaacag
    28981 aagttgtctg gctagctcct cccatggccg cagctactga aaaagccgct gtgtaggaaa
    29041 acatattgag caaggattta cccatagcca agccgtcaac taaactaccg cgaacctcat
    29101 gctggtctag gaaaattcct gtcatcaagc catcattcat aaagacttga tacaggacac
    29161 cattttctaa aacagtgaaa aagtcaggtg cttcttgacc ataaacatgg gcagattcat
    29221 agtccaaacc cttaaagcgg attttctcat aagctcctaa aacctcaggg aaaacctgtc
    29281 taaaggcttc tgatatagtc tgacgaatct gataaacata agagttatac caagaaaaga
    29341 cggcgtagtc gccataaagg tccactgtca gacccccaaa gccatctccc tcttgattaa
    29401 agagacgaaa ggcagttgtc aaatcatctt gatagtaggc gtttctcttt tctttggctt
    29461 ttctaaacaa cgtttcaaag aaagcttgat tgaaggccac cttgtctttg ctgataaacc
    29521 agcccaagcc cttgttttgc tgagaaaggt aggcagtccc aagaaagttt ccttcctgac
    29581 cctgcacctc tacttcctga tccttaagat tgacattctc aagatcactg gcttctagta
    29641 aaactagccc cttagcaagc ttcttttcaa cccttttgct gactcttatt ctattcataa
    29701 ctaccattat atcaaacttt tagacaattc tcaaaaaaga aactaccctt gcttttttac
    29761 tcttctttta aaaaatggta tactagactt cctgcaaaac taggaagtaa atgtgtaaga
    29821 atcacagtaa aaaatgctct tccgtcttgg aggagcattt ctttttatca acgaaaatca
    29881 aatagcaaac tatgaaacta gcctcaggtt aaccgtgaga ttataggtag agaggttgta
    29941 tcagcaatat gtgtctgtca aatttagtga caaaggtagt agaagaaaga tgaagaaata
    30001 aatcagcttc agtagatatc tggaaaattt gattttatag aaaagccttt tgttacaaac
    30061 tcaatatact atcaataaat aatattatag aagcaacaat aattaaaatt tcacctattt
    30121 gcatcattct atttcgaact ctaaatatat gttctatcaa aaatacttgg atcacacaca
    30181 ttataggaat taacgttttt gaaattgaaa aatatcccaa taaataaact ataaacaaca
    30241 ataatagaac tatattatat ttcttattca aaacattcct ccctatattt ttgattacca
    30301 atcttaatca tttacaacta cattctaaca aactataaaa gcgtttgtcg aattgaattt
    30361 atcaagcaag caaccaacca gctcatcttt tttctatttc tgccaatatg cgtgacaggt
    30421 aataatgata gccaaaaata gcaagagcaa gcaagacgat aagagctcct actcccaagt
    30481 tgatggcaag gataggggag agagactgaa ccaagaatat gctcccaatt acaagggcca
    30541 tcaggattgc actataaata aacaataaaa ctatggcgac tatgccattt gaacgattca
    30601 ccaggtccgt aatgctactc caattggttg acagattttt aacgtcctta aagtaatggt
    30661 ggcaagaaag gatgacactg gcaaggatcc atgccacaat aaggtaaatc atcgaaatga
    30721 tgggcaagcc tagatataga gaaagaccaa gcaaagtcag aactggtaaa aaggactgga
    30781 cagcatatat aatccaaaat ttcactttca cataacgagc aaagtcaaag ggtaaactct
    30841 taagaaaatc aacattttcc ctctccaagg acaaggcaat tgaatgcagg ctggtgatat
    30901 tgttattgac aactgctata aacactccta caaaaaacaa gggtaaccag tatggaggat
    30961 gaatgtctgg aactatctga gaatctcgga ttttggaaat cagaccgatc atcatgagat
    31021 aaggaaagaa agcacttgta aaaagcactg taaccacgcc agtaccctgt cccaagaggg
    31081 tgaggtggta gcgtaaaacc atgcggaaaa atcccttttt agtggttgaa attctctcct
    31141 tgctgcgacg ttcttttttg accttctcct cactattaag caggatcacg tcataaaaac
    31201 gaggaaggac cttctttttg gtcagataaa gcaggaagag agttagtcct atccaagcga
    31261 gcagacccaa tatggcttct gtcgaaaaag gatccactgc tattttgtaa aagatatgaa
    31321 gaggataaag gagaaatgga atgtctctaa ctttgtcaac aatacttcca aaagtcgact
    31381 gaagaaagaa gataaatatt aaaggtatga gaactcctat cccaatcatc acattcgaaa
    31441 aaatagactg atactttctg aagaccctag tttgagccaa gaaatgcact gccactacca
    31501 tcactagagc cacagagaca aataataagg tcaaggacag tagcatcaaa ggcaaaccca
    31561 gccatagaga aggagctagc ctaatgtaga ggaccagaaa ataagctagg attggtacaa
    31621 ttccagttag agctggcaaa aggacagaca gtcctttagc aattataatc tctgattctt
    31681 taaaggcata gggcctatac gatatcaaat ccttactctc ataaaagaca ttgtaaaagg
    31741 ccgttaaaga agttgaaaag gcaatcacta gtaaaatagc aatcatcaag ctaaaataaa
    31801 taggtatttc ctcaaaagga aaatgaatgg ctatattact aaaacagatg atcatcaaga
    31861 gactggaaaa aatgtaagaa cttaagactc tagcggaaac atttactttt ttcccaggat
    31921 tcttagcctg cttctttcgt agattagcca gattagcttc ttgagatgaa taaaggatat
    31981 tgatatcaac taatttttta atgaccttga gacgcatccg caacctcctc ttttctacca
    32041 gcaagactaa ggtagatact ttccaaagac tggtctgggt aatcttttct caagtcctct
    32101 acactaccac aataaatcaa atgccccttt ttcaaaatgg caatccgatc acagacttgc
    32161 tctgccacct ctaggacatg agttgaaaac aagactgtct tccctttttg tgcatgttcc
    32221 ttcatcatct gtttcaaatc aaaggcagcc tggggatcca aaccagtcaa gggttcatcc
    32281 aagacccaaa tatcgggatc agacaagagt gctccgatga caaagacttt ctgacgcatt
    32341 ccgtgagaaa gagtttcaat aacctgatag cgattttcag caaaatcaaa aacgttcaat
    32401 agcctagcta gactagcctc caagtcagat ctactcagat cataggatga ggcgatcaat
    32461 tcccaaaatt cattggccgt taagcgtaaa aataagtcag gcgagtctgc tacgtagcca
    32521 atctttcgtt taatagccaa gcgattttcc gataactcct gaccgtctac caaaatacga
    32581 ccactgctgg gtgaaatgat actgactagg gattttatag tggtcgattt tccagcccca
    32641 ttatgaccaa tcaagcccat aatctctcca ttttcaatct gcaaattgag attactcaag
    32701 gcctttttat caccatacaa cttactaaca ttttgaaatt caatcatggg acaactccta
    32761 tctttatctg tattatatat cgctatacta gcactttgat acaaaaaaat caatacttta
    32821 ttttaagtag ttaaaatagt ttccttctat cttacgcaaa cgtttgcgct aatagatact
    32881 ttatgataga ataaagaaca agattgacaa gtaagaggaa acattatgca aaatcaaaca
    32941 ctcatgcaat actttgaatg gtatctgccc cacgacggtc aacactggac gcgtctggct
    33001 gaaaatgctc cacacctagc tcatctgggg atcagtcacg tctggatgcc accagccttc
    33061 aaggcaacca acgaaaaaga tgtcggctat ggggtctatg acttatttga cttaggagag
    33121 ttcaaccaaa aagggactgt ccgcaccaag tatggtttca aagaagacta tcttcaagcc
    33181 attcaagccc ttaaagcgca gggaattcaa cctatggccg atgtggttct caaccacaag
    33241 gctgctgctg atcacaggga agcctttcaa gttattgaag tggatcctgt agaccgtaca
    33301 gttgaacttg gagaaccctt caccatcaat ggctggacta gttttacctt cgatggtcgc
    33361 caagatacct acaatgactt ccactggcac tggtaccact tcacaggtac agactatgat
    33421 gccaaacgcc gtaagtctgg gatttatctg atccaagggg acaacaaggg ctgggctaac
    33481 gaggaattgg tcgataacga aaacggaaac tacgactacc tcatgtatgc cgacctagac
    33541 tttaaacatc ctgaagtcat ccaaaacatc tatgactggg ctgattggtt catggaaacg
    33601 actggtgtag ctggtttccg tttggatgcc gttaagcata ttgactcttt ctttatgcgc
    33661 aacttcatcc gcgatatgaa ggaaaaatac ggtgacgatt tctatgtttt tggtgaattt
    33721 tggaacccag acaaggaagc caatctggac tatctcgaaa aaacggaaga acactttgac
    33781 cttgtcgatg ttcgtctcca tcagaatctc tttgaagcca gtcaagctgg cgcaaactat
    33841 gaccttcgtg gcattttcac agatagcctg gttgaactca agcctgacaa ggctgtgact
    33901 tttgtcgaca accacgatac ccaacgagga caagcccttg agtctaccgt tgaagaatgg
    33961 ttcaagccag cagcctatgc cctcattttg ttacgccaag acggccttcc atgtgtcttt
    34021 tacggagact actatgggat ttcaggccag tatgctcaag aagatttcaa agaaatcctt
    34081 gaccgcctcc tagccatccg aaaagatttg gcctatggag aacaaaatga ctactttgac
    34141 catgctaact gtatcggttg ggtacgttca ggtgctgaaa atcaatcccc aatcgcagtc
    34201 cttatctcaa atgaccaaga aaacagcaag tcaatgtttg tcggtcaaga atggactaat
    34261 caaacctttg tagatttact tggtaaccac caaggtcaag ttacaattga tgaggaaggt
    34321 tatggacaat tccctgtctc agctagatcc gtaagtgtct gggcagtcaa taccatctaa
    34381 tagctcataa taaccaagct aggtccaagc ggatttggct tttttgtatt cacaaaaaga
    34441 cctacccaaa tggatagatc tttacttgat tacaatttac ctgctactgc atccaacaat
    34501 tcttggatct taggttggtt gcttcctcct gccatggcca tgtctggttt accaccacca
    34561 cgtccatcga tgattggtgc taattctttg acaaggtttc ctgcatgaag gtcttttgtc
    34621 ttgcttgcta caaggacatt gactttgtca ccgatagcgg caactaggac aagaagatca
    34681 gagtagtctt tttgtttcca gttatctgca aaggtacgaa gggcacctgc atcggataca
    34741 gacacttgac tagcaatgta acgatgaccg ttgacttcct taacatcttt gaagatatcg
    34801 cctgcggctg cagctgcggc tttttctttc aactcagcat tttctttttg aagttgacga
    34861 agttgttctt gaagtccttc taccttgtga ggtacttcct tgacttgagg tgctttcaag
    34921 gttgctgcga cagctttaag agcatcctct tgttcacgat aggcttcaaa ggcttcctta
    34981 ccagtcactg ccaagatacg gcgagttcct gaaccgattc cttcttcttt gacaattttg
    35041 aagagaccaa tctcagaagt gttgccaaca tgagtaccac cacaaagttc aatagagtag
    35101 tcaccgatag tcacgacacg aacttccttg ccgtatttct caccaaagag ggccatagct
    35161 cccatttctt tagcagtgtc aatatccgtt tcaactgtct tcacttcaag tgcttcccaa
    35221 attttctcgt taacttgctg ttcaatcgca cgaagttcct cagcagttac tgcttggaag
    35281 tgggtaaagt caaagcgaag gaattcaact tcgttaagag atcctgcctg tgttgcgtgg
    35341 tttccaagga tattgtgaag ggcagcgtga agcaaatgag tcgcagtgtg gtttttcatg
    35401 acacggtgac ggcgattgct atcaattgcc aaggtatatt cttggttcaa ggcaagcggt
    35461 gcaaggactt caactgtatg aagggcttga ccatttgggg ctttctgaac attggtcaca
    35521 gtagccacaa tcttacctga ctcatccaag atttgtccgt agtcagctac ctgtccaccc
    35581 atttcagcat aaaatgacgt ttccgcaaag ataagagagg cagttccttc tgaaacagct
    35641 cctacttctg cattgtcagc aacgatagct accaatttag aagacaattg gctagtattg
    35701 tagttgaaga cactttctac agtgatgttt tgaagagttt cattttgcat acccattgag
    35761 ccacccttga cagctgacgc acgcgcgcgt tcttgctgtt ctttcatggc tgcttcaaaa
    35821 ccttcacggt ctacagtcat accagcttct tcagcgattt cttcagtcaa ttcaactggg
    35881 aacccataag tatcatagag tttaaagaca tcttgaccag caatgacaga ttgacctttt
    35941 tctttcaagt ctgccacaat gccttgggca aagtgttgac ctgagtgaag ggtacgggca
    36001 aatgattctt cttcgctctt aacgattttc tcaataaagt cacgtttctc aagcacttct
    36061 gggtagtagc tttccatgat ttttccaaca gttggaacca atttgtaaag gaaaggctcg
    36121 ttgataccca atttttgacc atgcatagaa gcacgacgga gaagacgacg aagaacataa
    36181 ccacgacctt catttcctgg aagggcacca tcaccgatag caaatgaaag agaacgaatg
    36241 tggtctgcga taaccttgaa gctcatgttg tcgccatctt ggtcataaac cttaccagac
    36301 aatttctcga cttcacggat aatcggcatg aagaggtccg tttcaaagtt ggtcttagcc
    36361 ccttggataa cggccaccaa acgctccaaa ccagcgcccg tatcaatgtt cttatgtggc
    36421 aattccttgt attcgctacg aggaacagca gggtctgcgt taaattgtga caaaacgatg
    36481 ttccagattt caatataacg gtcgttttca atatcttctg caagcaggcg aagaccgata
    36541 ttttctgggt caaaggcttc cccacggtca aagaagattt ctgtatctgg tccagaaggt
    36601 cccgcaccga tttcccagaa gttgtcctca attggaatca agtgacttgg atccactccc
    36661 acttcaatcc agcggttgta agaatcttta tcgtctggat agtaggtcat gtaaagtttt
    36721 tcagcaggga aatcaaacca ttcagggctt gtcaaaagct cataagccca agtgatagct
    36781 tcgtcacgga agtaatcccc gatagagaag ttccccagca tttcaaacat ggtatggtga
    36841 cgcgcagtct tccctacgtt ttcgatgtcg ttggtacgga tagccttttg ggcattggta
    36901 atacgtggat tttcagggat aatggtcccg tcaaagtatt tcttaagggt tgctacccca
    36961 gagttgatcc acaaaagagt tgggtcattt acaggaacca aacttactga tggttctact
    37021 gagtgacctt tggtcgccca gaaatcaagc cacatttggc gtacttgtgc actagatagt
    37081 tgtttcatat tgtctcctta ttcacttgtt taatgtgatt ggctttccag catttccaca
    37141 tagtcaatcg cgacacagag ggaaatgact aggtctgcat aagcgtcttc aagaaccgtt
    37201 acggtatagg tagaggtcag atggaagagt tccttcttaa tttccgcaat caactgatcg
    37261 cgatcatcca gcaatttgaa attcaaatcc cagatattgc cctcgatacg aagacctaga
    37321 ttatcaaact catacttatc tcgccagaag gtcaacttct tacgaatgac aaaactcgag
    37381 ccatcccgaa gctgaatctc aaaacgagga agcaaggtca agatttcttt actgatctga
    37441 ctgacttgtt caccagccgc atcatagatg gtaaaagttt tgggaatctt aaaaaatgat
    37501 ccctccacct gataggcaat ttctcccctg tcatccttga tagcgaagcg ttcgcctcca
    37561 agacgaaact tttgtttgac aagaaatgtt ttcatcaaca cctccaaaaa tcaaaagaca
    37621 agctcatatc acgaagggcg aaaaaccgcg gtaccacctt cattcaatga acttgtcatt
    37681 ctcttgttct tatgcaattg tatgattgag tagcatgact tcctagctta gatggctcgc
    37741 agcaccgcca tttctctgga ctaagacaag tgaaaatcaa ttctcaactt tcttattata
    37801 acgttttttt aagcttgcgt caactggaaa tgatctccgt tgaattagac caattcccta
    37861 catctctgat tactttttca ggatatattt tttcttactg ccatttttct ttttatccca
    37921 aattttcata ttactaaaca cagctactag aatatttcca aatataaagg tgcctatcac
    37981 ccaatatatg gactcagttg ttaggtattg tcgatccaag ccatcattta aatggaatag
    38041 tatagcagtt tggttaacaa tcataaaggt tggccagaaa ctttttttga aaaaagtaga
    38101 cattttcatt atttgttgcc gctttctgta aggttaatac tcaataaaaa tcaaaaagca
    38161 aactaggaag ctagcctcaa gctgtacttg agtacggcaa ggcaacgctg acatggtttg
    38221 aagagtatag gcttagtata ctactaggca agcaaataag caaataagca aataagcaaa
    38281 taaacaacta gaatagaaaa agatagggct ctaaaaactg acttctattc cttaaaaacg
    38341 aaccagcttg actgattcgt cttcttacgt ttatctccta cttccgatac attttaaact
    38401 gtaggaagag gtcgctatat ttccctgtcc atttatggtc aaatttctca taaacttcta
    38461 ggtgtttcat ggtttcaaca tcgggataga aggccttatc ttcctttgtt tcctctggga
    38521 gcaattcctt cgctggtagg tttggtgttg aatagccgac atactccgca ttttggagag
    38581 cattttcagg tttcaacata aagttgataa aggcataggc tgagttttgg tttttaactg
    38641 ttttgggaat gaccatattg tcaaaccaaa gattgctggc ctctgtcggt accacataac
    38701 gtagattttc atttttttct aacatttggc tggcttcacc agagaaggtc acgccgattg
    38761 caacattatt ctgaatcata tagcccttca tctcgtccgc aacgatagcc ttgatatttg
    38821 gagtcagttt gtagagctta tccactgtct cttccaactg ctgcagatcc ttggagttga
    38881 ggctgtagcc gagggaattg agtcctagtc ccagcacctc acgcgcccca tcaaagagca
    38941 tgatagaatt cttatactcc ggcttccaaa ggtcatccca atgctcaggc gcttcatcta
    39001 ccatggtttc gttgtagaca attcctaagg ttccccagaa gtaagggatg gagaatttat
    39061 tacctgggtc aaaggactgg ttgagaaact ctgatccgat attttcgatt ccttcaattt
    39121 ttgaataatc aagcggaacc aagaggtctt cgtccttcat cttgttaatc atgtattcac
    39181 ttggaatggc aatatcgtag gtcgttccac cctgctttat cttagtgtac atggcttcgt
    39241 tggagtcaaa agtctcgtac tgaacttgaa ttcctgtttc ttctgtaaac tgagtcaaga
    39301 gttcaggatc gatatagtct ccccagttat agataaccaa tttttgacta tctcgactat
    39361 tgattttact atctaaatga gtcgcaattc cccacaagac aaggataatc gctgcaattc
    39421 ctgctaaaaa tgaatagatt tttttcatgc ttgctcctcc ttctcacgag agataaagta
    39481 ataacctaca actaggataa tactaaagag aaagactaga gcagacaggg cattgatttc
    39541 taaggaaatc cccttgcgag cacgagagta aatctcgact gatagggttg aaaagccatt
    39601 tcctgttaca aagaaggtca cggcaaagtc atctaacgaa taggtgaagg ccatgaaata
    39661 accagtaatg atagacggag tcaggtaagg aagcatgatt tccttgaaca tctgaaattg
    39721 actagctccc aagtcatagg ccgcatgaat catgtcgcca ttcatttcct tgagtcgagg
    39781 caagaccatc aagaccacga taggaatgga gaaggccacg tgactagata gaacggtcaa
    39841 aaagccaagt gaaaacttga gttgggtaaa gagaatcaag aagctagcac caatcataac
    39901 gtcaggcgca accatgagga tattattgag tgatagaaag gcttcttggt atttcttacg
    39961 agactggtag atgtaaatgg caccaaaagt cccgataatg gtcgctatca aggctgatag
    40021 gaaggccaag aaaaatgtct gagccaaaat cagcatgagt ctcccatctc caaacatggt
    40081 ttcaaagtga gtccagctaa aacctgtaaa gctattcata tcatcaccag cattaaaggc
    40141 atagccaatc aagtaaaaga taggcaggta gaggaccaga aagaccagtc ccagataaag
    40201 gttggcaaat tttttcatcg ttctctcctt tccttagtca cccacatggt gatgaacatg
    40261 gtcaggatga gaatcacacc gatggttgaa cccataccat agttgtcatt ggttagaaaa
    40321 ttctgctcaa tagccgtccc caaggtgata acgcggttcc caccaatcaa acgggtcagc
    40381 atgaagagac tcaaacttgg gataaagacc gactgaaccc cacttcgcac accgttcata
    40441 gatagaggga agatgacatg acggaaggtc tcccacttag ttgcaccaag gtcataacta
    40501 gcattgatga gattattatc catatcgtct aagacattga aaatcggcaa aatcataaag
    40561 gggagctcga tgtagcttgc gacaaagata aaggaaaaat cggtaaaaag caactgttgt
    40621 gaaccaattc cgataaattc caagaattgg ttaatagagc cattttgacc aaaaatcccg
    40681 ataaaagcat aggctttaag gagcaaattg atccaggtag gaaggataat cagcatgagc
    40741 cagagttgac ggtgcttgag acgggtcaaa aagagggctg ttggatagct gataagcaag
    40801 gtcacaaagg tcacaatccc tgcataaagc actgagttga aactcatttt gaggtaggtc
    40861 aagttttgtg acgcaaagta agatttataa ttttctaaac taaactggcc ttcaatgttg
    40921 aaaaaggatt gtccgaaaat caagaccaag ggtgccaata caaagagggc aatccaaagc
    40981 atgtagggca ctacaaagag tttagagctt gttttcttca tctctttcct cctcgatcgc
    41041 attgatcaga cctgcttctt gctcttcgat ttccacgtat tcttcgatac gagcatcgaa
    41101 ctcttcttcg gtttcattga gacgcatgat gtggatgtct tctgattcaa agtccagacc
    41161 gatttcctca cccacgatgg ccttacgggt tgagtggatc atccattcat ttccaagttc
    41221 gtcataggcg ataatttcat aatgaactcc acggaagagc tgggtgtcga ccttaacttg
    41281 gagtttgcct tcttcaggaa gggtaatgcg caagtcctct ggacgaataa cgacctcaac
    41341 aggttcattt ggcttcatcc caccatcaac cgcttcaaag cgtttgccgt taaattcgac
    41401 caagtagtcc tcaatcatgg tacctggcaa gatgtttgac tccccgataa aggtggcaac
    41461 aaagtggttg attggctcat cgtagatgtc cacaggggtt ccagactgga caatctcgcc
    41521 atcattcata acgaaaatcc agtcactcat ggcaagagct tcttcctgat cgtgagtgac
    41581 aaagacaaag gtaatgccca atcgttgttg taattcacgc aattcgtact gcatgtctgt
    41641 tctcaatttc aagtccagcg ctgataaagg ctcgtccaac aagaccacac ggggttggtt
    41701 gatgatagca cgggcgatgg ccacacgctg acgttgtcct ccagaaagtt tgcggatgga
    41761 acgtttttca taaccttcca actgaaccat cttgagaact tccgctacgc gttgctcgat
    41821 ttctttcttg tcaatcttgc gcaagcgaag tggaaaggca acattttcaa acacattcat
    41881 atgtgggaac aaggcatagg attggaagac agtatgtacg tcgcgcttgt tggttggaat
    41941 atcattgata cgaacaccgt ctagcatgat atctcctgtc gtcgcatcca gtaaacctgc
    42001 aataatgttt aggatagttg atttccccga accagatgca cctagaaggg tgtagaattt
    42061 cccttcttcc aactcaaagt tgatgtcttt gagaaccttg gtgttgctgt cttcaaaaac
    42121 tttagagacg tttttgaatt cgataattgg ttttttcaat tggcataaat tccttctttt
    42181 tcatagatta accgatcggg gctctgtcag gtccccacta cctcttgcag ggagtaaaac
    42241 cacctgcata catcttcgct accgataggc tttcaccccc ctttccatga catagcagca
    42301 gcttttcaaa tacagcttcc tacttgcttt cacccaagat ccggacttct ctttcaagcg
    42361 taatacctga gtgttccttg actttttcga taaccgattg gatcaagtcc tcgtagtctt
    42421 tggccgttcc atctgcgaca ttgatcataa atcctgcatg cttttctgac acttctacgc
    42481 caccgatacg atagcctttc aagccagctt ctgaaattaa ctgacctgca aaatgcccga
    42541 ctggacgctt aaagaccgag ccacaagatg ggtattccaa aggttgcttg agttcacgta
    42601 ggtgcgtcaa gcggtccatt tcctgcttga taacctgatg ggttcctggg gctagggcaa
    42661 atttaactga caagacaact gcaccagact cctgaatagc tgaatggcgg taaccaaaag
    42721 ccaagtcttt agcagacagg gtttcgattt ctccatcctt ggtcaagacc ttacaagact
    42781 gcaatatgtg agcaatctcg ccaccatagg cacccgcatt cataaagaca gcaccgccaa
    42841 cgcttcctgg aataccacaa gcaaactcaa agccagtcaa actatgacgg agggcaatgc
    42901 gagttgtttc aatcaagtta gccccagctt ctgcttcaat ggtatagcca tcaacagaaa
    42961 cgttattgag cttgtcacac aagatgacaa atccacgaat cccaccatca cgaacgatga
    43021 tattgcttgc attgccaaga accatccaag ggatattttc ttggttggca aatttcacaa
    43081 ggcgagccaa ctcaaaacga tttcgtggaa agaccaaata atcagcctct ccacctactt
    43141 ttgtataact atagctatgc aagggttcct gaaaacggat atcaattcct tctaagattt
    43201 caagcatttt ttctcttaca gacatgtcac tcttcctttt acaaaattca ttccattata
    43261 ccatttttag agacatttga cgaccataaa aataccttgt ttggattttg cataagaaaa
    43321 agaggttccc ctctttttat gattttttac aaaagatttc cttggttcca taggcgacca
    43381 gaacgagctc cagtgctaga atcacttcaa ccaagactgg atttgtcaac cagcctactt
    43441 ggaaaagaga tggtgccaga tcaaagaagg catgcaagcc ataggctgtt aggagataaa
    43501 tccatttctt ctggcgaaca gcttgataaa cccaaactgt caaaagtaat tggaaaccaa
    43561 gcgccaagat tcgctcaaaa ccaagcaaat aaatctgcca gaccgaaagt gactgaatgg
    43621 tttttaacat attttcagac agtaattgca taacctgtgg attctgagtt tgaactgccg
    43681 aaagaacaat gtaaagattg agtaaactag taaggcctag aaaaatcaac tccaagccac
    43741 catgccccaa tccataggcc aaggcgtctg ccttttccaa acttctcttt ttctccaacc
    43801 atttgaagaa aacaagacga gccgtttcct caaaaaatgc taccatggct aggccataga
    43861 taatatagat aagcggatga acttacaaga gggcaatact accgtctttt tgaggatgca
    43921 aaatcaagat atgcaccagt ttttccaaaa tctgcgaaga gacaaagaaa gcgactgcac
    43981 ccaagtccaa gacagctaga ttaatctggt atttcttttt ggcaaaccaa atgcttccta
    44041 tcagaaaagc tagcaacagc aacatggtaa taatgatatg aatggtcatt ttcttctcct
    44101 attctgcctt ttcaatatct tttttcatct cgtcaacatt gaacttagca aacaagtatt
    44161 gacggtcttg gactgggaaa cgttggtcca actggtcaac tgctcccacc tcgataatgc
    44221 cttccttgat gacaaaatcc atgacatgtc caccgaaggt caaatcatct gatatgaagt
    44281 gcagatggta gcctgccaca ctgaccccat ggaaaatctc aggcgtccag aaaccaacaa
    44341 tagtccccgc aacattgtca cgactatatt ccggttgatg ggttgcgaca tcagcaaact
    44401 tggtatcggg tgttgactta ggaatcatac gcacatgcat atgtgaaaat tccccccgaa
    44461 tcttgataga gcggaaaaga ttttccccat cataataaga ctcaattcgt tctttcaatt
    44521 ccttgtctgt catctcaaag cgctggcgga aaatgacctc tgcctgatgc ggtaccactg
    44581 cagcgtaagg aataagggca tctggtgaca cttccacaat ttctggctgg tctcctgacc
    44641 ctttggcctg ataagccttg ccatccaaga caatcaattc cccatcaatg gaatccaagg
    44701 ttcccaaacc aaggtcacca tgttctagca attctcctac tgtcatagta ccaccataaa
    44761 ggccagccat caaggctcca agagtattgt attgaaataa tttcactggt tcctgcacgt
    44821 tcttatccat tcactttctt gtctgttatt ctataaatct tactcctaag tataccacat
    44881 ttgcccctag atgtgaacga gagaaacgct ctagacattg ccaagaagga aaaacagggt
    44941 acaatgtaac aaaatcaagg gaggtctgga atgaagaaac aaagcaagta caaagaggtc
    45001 gtttcctatc tgaaaaatgg tatcgagtct ggacgatttc cgacgggtag cctgagattt
    45061 tgacagaaac aaaacttgca ctagcacaac aacccctaag gaacacactt ccctaggggt
    45121 cgctttttat ttaactaaat cattatttat tttttgttcc tagtaaacat aaatattgta
    45181 ttaataattg caaaaataaa tgcaaacaaa aggattttcc aaaggataaa tttttgtaac
    45241 actaaatatg catatacaaa tccaatcaaa aagctaataa tcccatcttt tattaaaaag
    45301 tttttatcac gcattattcc agaccacact gaactgccca aatagccaac tgaccagcaa
    45361 tgatataaat atttgtttta agtccattag ctttaacaaa tcttagtacc actttagcta
    45421 attctgacca agcctttttc tgcgcatact taacaattag cgaaacattg atcatagcaa
    45481 aaaattcatc tcgtattttt cctgctatac atcctcccat ctcatcccaa gggactctgt
    45541 catagggatt attaatatta gtttctaatt cattttccgc aagagcaata tctttttgag
    45601 aaaagttttt ataaacatat tcagtaaaat ttttttcatt aactccattt ctaaacattt
    45661 gttcaagaac attggctaca tcatcgattt gtttttgttc ttgggtacta atttcagaaa
    45721 cttccgtagt agttacatca tcagcaaata ctctaacaga agctatagaa ggagacataa
    45781 tagaaaatag tgataataca acaagagctg aagttacaat ttttttaaat ttcataaaaa
    45841 acactccttt caagtcacaa atatatatta ctgataaaat aacttgattt tctgatttaa
    45901 aactcctttc taacaagtta ttcgtatgct tttatttttt agttctatta taccacaaca
    45961 agaaaacgat ttcaagcatt ttcctaaaaa tatgtacaag taatatgtac aagtaataag
    46021 gggaaattag cataaaaact ttttaaaaca aatcaacccc agataaaaat acacatgttg
    46081 ttttaaagac aaaaaagggt acgaaaaact gtcacatctg catttgattg ctctttgatt
    46141 tcaaaaaagt attaaaaatg ggagtatacc acatttgccc ctagatgtga acgagagaaa
    46201 cgctctagac attgccaaga aggaaaaaaa agggtacaat gtaacaaaat caagggaggt
    46261 ctggaatgaa gaaacaaagc aagtacaaag aggtcgtttc ctatctgaaa aatggtatcg
    46321 agtctggacg atttccgacg ggtagtcgcc tgccttctat ccgtcaactg agccttgact
    46381 ttcactgcag caaggacacc attcaacgag ccctgctgga attacggcac gaacaatatc
    46441 tctatgccaa gcctcagagt ggctactatg tattagaaca agggcaacat caagacctag
    46501 aaatcgaggt taccgacgaa catgccagtg cctatgacga tttccgactc tgtgtcaatg
    46561 aaaccttgat tggccgagaa aactacctct tcaactacta tgacaatcaa gaaggattag
    46621 aagacctaag acagtccatt cacaaactcc tctttgagca agctctctac tgcaaggcta
    46681 accaactagt actgacttct ggaacccaac aagccttgtt tatcctctct caaatatcct
    46741 ttcctagaca agccaaggaa atcttggtgg aacagccaac ctaccatcgg atgaatcgcc
    46801 tcttgattgc acaggggctg gactatcaaa cgattgaacg aggcattgat gggattgact
    46861 tggaggagct ggaaggccac ttcaaaacag gaaaaattaa atttttctac accattccta
    46921 gatttcacta tcctctggga cattcctatt ctgagcagga caaacgatct attcttaact
    46981 tagctgccaa gtatgatgtc tatatcgtag aggacgatta tctgggtgat ttggactcca
    47041 agaagggcca aaccttccac tatcttgata cagaggagcg tgtcatttat atcaagtcct
    47101 tctcgaccag cctttttcct gcccttcgta ttacagcact cattcttcca aatgctatca
    47161 aagaagcatt tgtggcctac aaaaatatcc tagactacga cagcaacctc attatgcaaa
    47221 aggccctgtc actctatatt gacagtcaat tgtttgaaaa aaatcgtttg gctcgcttga
    47281 ccaatcatga atcttaccaa aaacaaatcg aggaaaggat aactaaaaca ccttgtcccc
    47341 ttcctcatta tcccctacac gatggtttat tgctagacct gagacagtat cctaaaatcg
    47401 ccagtctcaa acacagtcaa ctgggcttgg acttctttga agaggcctat ttaagcacct
    47461 gtccttatca atttgccaag gtgtccctag acaatctgga aaatgtttta aactatttaa
    47521 aagcagaatt ggaatgacat ccaactctgc tttttcttat tcttcaactt cagttaaact
    47581 tgctgctttt tcaagatagc tttggtaagt tccttcatcc ttaagttttt ggatgacctt
    47641 gtctaccact tctttcaaat catcactatt ttttctaaga gcaacggcat tggcgtcgcc
    47701 gtccttcatc ttcaagctga cagttgcgac agctaagcca gcgtttttag cagcataact
    47761 aagtgcaaca ggctcatcca tatgaacagc atctactttt ccagcctgca attcattgac
    47821 tgcttcaccc atattagtta gggaagttaa ttgagctttt ggcaattgtt ccttgaccat
    47881 tgattctgga acagtccctt tttgggctgc aatattagca ctttctaggc tagttaaatc
    47941 cttgtatttt tccacatcag ccttacgaac caagaaacta atcttgtttt catagtatgg
    48001 gattgaaaaa tcaaagactt cttttctctc gtcagtagca ctaattcctg caactgctag
    48061 gtcagcctta ccagtttgaa gactggtcaa aacattatca aaactcatgc ttgagatttc
    48121 caacttaacc ccaagttcat cagcgatagc ctgagccatg tcgatgtctg caccgactac
    48181 ctggttcttt ccatcaacca atgattgaaa ttcaaagggt gcatagtcag gactggttgc
    48241 cacaactaat ttcccctttt gcttaatggc ctcaacagct gactgagaac cattagaacc
    48301 tgactggcaa gctactaaga agaaacttgc aagaaaatta cataaaacaa atatccattt
    48361 tttgatttca taaataaaca acctctctgt taattttgta taattataac gatatccaag
    48421 ttacttgtca agtgtttttt aaatttttat ctcaaaaata ttttttcgtt caaaaaaagg
    48481 agccatcagt tgatttcaag ctccttttta tacagaatta aactatttta tagttcgaca
    48541 atcttacctg tttcaaagta gacaacccat tcacagatat ttttagcata gtcaccgata
    48601 cgctccaagt aggaaataac ttggaaataa tcacgacccg taacaatggc ttctggattt
    48661 ttcttaatct cttcagtcgc aaggtcacgg atagtttcaa aatagtggtt aatttgctca
    48721 tccatggagg ccacccggta tgcgtcgtca acagaaccat taagataaag atcaagtgct
    48781 gcttcaacaa cgcttttaac ttcacgtccc atttttttaa tttcttcctc tacagctgga
    48841 atgcgctctt cccccttcat acggatggtt gcctgagcaa tggctacagc gtgatccccc
    48901 atacgctcca catctgatac agccttaagg acagtcaaga ctgtacgcaa atcttgagag
    48961 actggttgtt ggagtgcgat catttcaaat gatttctttt ccagtttcac ttcgtattca
    49021 tttacttctg catcatcttc gatgacctct tttgccaggt cacggtcatg cgtgacaaaa
    49081 gcacgtaccg tacgattgat ttgtgagagc acttcttgtc ccatagcgta gaactggtta
    49141 tgtaatttct ctaaatcttc ttcaaattga gatcgtaaca tctttcatct ccttatccaa
    49201 attttcctgt aatatagtct tccgtttcct tgtgttgggg attaaggaac atctgcttgg
    49261 tatcattaaa ttcaatcaaa tctccatcta ggaaaaatcc tgtcttatca gagatacgtg
    49321 aagcttgctg catggaacgg gttaccagaa gcatggtgta cttgtctttt agaccataca
    49381 aggtttcctc aattttacca gctgaaatcg gatccaaagc cgaagttggc tcatccaaga
    49441 ggatgatttt aggactagtt gccaagacac gggccacgca gacacgctgc tgttgaccac
    49501 ctgacaatcc aatagctgaa tcatatagac gatccttgac ctcatcccag atagaggcac
    49561 cttgcaaggc tttttctacg gcttcatcca gaacctgctt atccttaatt ccattgatac
    49621 gaagcccgta gacaacattc tcatagatag tcatagggaa aggattaggt tgttggaaaa
    49681 ccattccgat ttccttacgt aattcaaccg tatctgtacg cggactgtag atgttgtgac
    49741 cattgtacac cacggatcca gttgtggtca cctctggatt gagatctccc atgcggttga
    49801 gagacttgag gagggttgac ttccctgatc cagatggacc aatcaaggct gtaatttcct
    49861 taggttggaa agatagggaa acactattca aagccttctt tttattataa taaacggaca
    49921 ggtctgatac ctgtaaaatc gcatctgtca tacggtttcc tttctaacca aagtgaccag
    49981 atacatagtc attggtggac tgtagcttgg cattttggaa aatagttgca gtcttgtcat
    50041 actcaatcaa atcacccaag taaaagaagc ctgtatagtc acttgcacga gcagcctgct
    50101 gcatattatg cgttacaatg atgatggtaa agtttttctt gagctcaaac atggtctctt
    50161 ctagttgcat ggtcgcaatc ggatccaagg ctgaggctgg ctcatccatt aagaggatat
    50221 ctggcttaac agagatggca cgagcgatac agagacgttg ttgctgacca cctgataagg
    50281 tcaaggctga cttgtggaga tcgtctttaa cctgatccca aagggcagcc tgacgaaggg
    50341 aggtttctac gatttcatct aggacttgct tatccttaac tccagcacgt tcatgcgcaa
    50401 aggtaatatt acggtaaatt gacttagcaa atggattggg gcgttgaaaa accattccaa
    50461 tgtgtttacg catttcataa acgttgattt ctggacggtt gacatcaatt ccacgataga
    50521 gaatctgccc agttacttta gcaatatcaa tggtatcatt catgcgattg agactgcgta
    50581 agtaggtaga tttccccgat cccgacggac caatcaaagc tgtaatttta tttctttcaa
    50641 attgcatatc aatcccctta atggattcat ttttaccata gtaaacatgg acatccttag
    50701 tagaaagggc tactttttct tcaggaaagg taaggatatg cttctcatcc cagttatatg
    50761 ttgacatggc ttctccttta ggcagcggtt aatttcttgt gtagatagct tccgaactta
    50821 cgagctccaa agttaaaaat caggataaag atcaggagca cagcggcaga acctgctgat
    50881 acaatggttc catctggaat agtgccttca ctattgactt tccagatatg gacagccaag
    50941 gtttctgctt gacggaagat agagatgggg ctagtcacac tgaggatatt ccagttagac
    51001 cagtcaagag ctggcgccga ttgccctgct gtatagatca gagctgcagc ttcgccaaag
    51061 atacgaccag atgccaaaac gacacccgtt acaatacctg gaagcgcttc tggaataaca
    51121 acatgaacca ctgtctccca gcgagaaatc ccaagagcca gaccagcctc acgttgggta
    51181 tggtgaacgt gtttcaaact atcctctaca ttacgcgtca tctgaggcaa gttaaagact
    51241 gtcaaggcca aggcacctga aatgattgaa aatccatact caaactggac tacaaagatc
    51301 aagtaaccaa agagacccac caccactgat ggtaaagagg acaagatttc aatacaagtc
    51361 cgcacaaagt tggtaacagg acctttttta gcatattcag ccaagtaaat cccagctccc
    51421 atagaaagag gtacagaaat aatcaaggta atgaccaata ggaaaaagga attgtaaagc
    51481 tgaatgccaa tcccaccacc tgcttgaaaa gcagaagacc ttccagtcaa gaaagaccaa
    51541 gagatatggg gcaagccccg aaccaagata tagagaatca aggaagccaa gattgtcaca
    51601 atgatgctag caatcgtata gaggacagct gttgcaagtt tatctaattt cttagcgcgc
    51661 ataatttttc tttcctcttt ctttcgtaat caatttaatc acactgttaa aaactaaact
    51721 catcaagagc agtaccaagg ccagtgacca gagaacatta ttatttacag ttcccatgac
    51781 agtgttccca attcccatag ttaatataga agttaaagtt gcagctggtg tggtcaagga
    51841 agttgggata acagctgagt ttccgacaac catctggata gctagagcct caccaaaggc
    51901 acgcgccatc ccaaagacca ctgcagtgaa aataccagaa cgggccgcct tcaagatcac
    51961 acgccagata gtctgccagc gagtggctcc catagcgaaa ctggcttcac gataataacg
    52021 aggaaccgca cgcaagctat ccgttgtcat aaaggttacg gtcggcaaaa tcatgacaaa
    52081 gaggacggaa atccctgaca aaatcccaaa accagtccca ccaaagacac tgcgaacaaa
    52141 gggaacgacg acttgcaagc caataaatcc gtacactact gaaggaatcc caaccaggag
    52201 ttcaatagct ggttgcaaaa tcttcgcccc ttttggtgat acttcggtca taaaaactgc
    52261 tgcaccaata gcaaagggtg ttgcgataag ggctgagaga atggtaacga taaaggaacc
    52321 caaaatcata ggaagggcac caaattcttt actagaagga ttccaagttc ctcccaaaag
    52381 aaagtcaaag atattcacac cattgacaaa gaaggtcgac aagccttttt gcgctacgaa
    52441 aaccaaaatc atggccacaa ggatgactat caaagaaaga caggcaaagg tcaaaccttt
    52501 tcctaatttc tccagacgag aattctttga tggaagcaac attttcttag ctaattcttc
    52561 ttgattcatt attgtctccc ttccaacact gtcacagttc cggcagcatc tttttcaacc
    52621 ttcatttcct taatcggaat atacttcaat cctttgacaa tcccttcttg ggtctcatcc
    52681 gagagaacaa aattgagaaa ttctgcagcc aactcattgg gctgccccaa tgtatacata
    52741 tgctcataag accacaaggg ccaattattg ctacttatat tttctggact taagtcatag
    52801 ccattcaact tcatgctttt gaccgaatca tctatatagg taagagataa ataagagata
    52861 gctcctggac tttttgatac gattgatttt accgctccat ttgaatcctg ctcctgactt
    52921 tgcatggcag actgaccttc cataatgaca gtatcaaagg tagcacgaga gccagagccg
    52981 gctgcccgat tgataacaga gatgggtaag tccttaccac caacctcttt ccaattggtt
    53041 acctcaccta tgaagatttg acgaagttgc tctgtcgtta ggttatcaac atcaacctcc
    53101 ttattgacaa tcagagccaa gccagctacc gcgaccttgt ggtcaacaag agcagaagca
    53161 tcaattccgt ctttttcctc agcaaataca tctgagtttc ctatatcaac tgccccagac
    53221 tgaacctggg acaagcctgt accagaacct cccccttgga cattgaccgt ttttccaaca
    53281 tggatcgtgc caaattcatc tgccgctact tcaaccaagg gttgcaaggc agttgagcca
    53341 acagccgtta tggattctcc acgatcaatc cagctagcac agcctactaa acaagccgtc
    53401 agccaaaaag cgataagaga cagagcaagc ttttttcttt ttttcactgt ttttctcctc
    53461 gaaaataatt atgaatactg tgaatttttt aagtagttct ttatgagttg acgcatgaat
    53521 tcttaccaaa tttctgcgca attgattatt tatataatat aggctatatt actctttcct
    53581 aacctccttt tttcatatgt ggataaaatc tcttgtctat cccttccccc attgtcaccc
    53641 attatagtca tttcgtgtct ctttttcccc tttttaatgc aagggaaatt actcttctta
    53701 gatgataatc caaaagctag aaaggtatct caaacctctc tactctccca gactagttta
    53761 caactaaaag gaaaagattc tattttatga gaaatctagt ttacaagcgg taagaacgct
    53821 aataactaaa cttcttgtac tctttgaaaa tctcttcaaa gcagtgtttt gagctatcta
    53881 tggctagctt cctagtttgc tctttgattt tcatcgagta gtaaaactac atgtgatggc
    53941 aatcaagata tcaagaatca tcctactaaa aaaatccata ctttcactat aacatagaat
    54001 aagatatttg actagcattt tcatttgaat ctgaggcctt ttggaaaata atttttcaaa
    54061 acatttccag taacctttgc aaagcccaag ccattgcctt taaccaaaac ttggtaccaa
    54121 ccatttggca gactttctgc cagctgaacg gtttctccag ccgcatactt gacaaacgct
    54181 tcttggccaa tttcaaccga ctgttcgacc tgactcggtt tcaaggctaa accaagagcg
    54241 aaactgggct caaagcgttt cttcttaaaa gtacccagat gcagtccatt gcgagcaatc
    54301 ttgagcttcc ctaaatctgg caaaagttct ggcaagagat aaagctggtc tccaaaaatc
    54361 tgcaagatac ccggtagatt gaccttcaaa tggttttggg caaattcctg ccacaaggca
    54421 acttgttcac ggctgaggtt actcttactt gccttaaatt taggagctgg attgttaccc
    54481 ttaaactgta gatgggcaac aaactgaccc tctcccttaa actgatgagg gtacatccga
    54541 gccgtttctg gcaggtcaat accagctacc attccattga tatgctctac tggcaacaag
    54601 tcaaaatcat actcttccag caaccaattg acaatctctt cgttttcctc gggtgcccag
    54661 gtacaggtcg aataaaccag acgaccacct tcagctaaca tggtcactgc atcctccaga
    54721 atttctcttt gcaagctagc acattgactc ggataatcta agctccaata gtccatagca
    54781 tcaggttgct tacgaaacat tccttcacca gagcaagggg catcaagaac gattaagtca
    54841 aaatagcctt taaagacctt gaccaagcgg tcggcagatt cattggtcac cacgacattt
    54901 gtcgctccaa aacgctccat gttttcaacc aaaatcttag cccgtttgct tgaaatttca
    54961 ttggaaacaa gtagcccctc ccctgctaga taggctgcca gttgagttga tttgcccccc
    55021 ggtgcagcag ccaagtccaa gaccttcata ccaggactgg gttgggctac ttgagccacc
    55081 atttgagcag caggttcttg cgaataaact aaacctgtag catgctcagg cgatttccct
    55141 gaaaccttcc catagtggcc ccaaggggtt tgagtaatgg catcagaaaa ggaaagttgc
    55201 tcttctttta agggattgac ccgaaaggcc gaaaccgctt cctcctcaaa agaggcaaga
    55261 aaatctcttg cctcatctcc tagtatttct ttatattttt caacaaatcc ttctggaaat
    55321 ttcatttaag ttcttttcct ttcgtaaata taggactgaa tttcctcctg catctcaaga
    55381 ggcaccatca tgaccggctg tctggtttga aaatcaggag cttcaccaaa aagggtcaca
    55441 acccgatagc ccagactttc ccctaaaata ctagctgcgg cataatccca tggttgcaga
    55501 taggtgagat aggtcaacaa atgccctgac aaaatcttgg caaaactaat ggccgcactt
    55561 ccatagacac gaacaccaag aaccgctcgg ctcaaatcag ccagccccca ttcattggtt
    55621 tccagcatac cactattccc tgcaatgaga aaatctccaa gtggtttagt tttaaaagga
    55681 gctaggggcc tatcatttag acaaactgga aattccccac caccgtggta acaatcccct
    55741 ttgaccacat cataaatcag accaaactgt ccctgaccat tttcaaaata agccatcata
    55801 acagcaaaat cttcctgctg ggctacaaaa ttattggtac catcaatggg atcaatgacc
    55861 caaaccttgc cctcttgaac cgaggctcgc agacaacctt cttcagcaca aatcttatcc
    55921 tcaggataac gggacaaaat ctcaccaacc aagagttcct gaacttcttt gtccagtctg
    55981 gtcaccaaat ctgttggaga ggacttggtt tcaacacgca agtcttcctg catatggtca
    56041 agaatgtact ggcctgcttt cttaacaagc tctttagcaa attcaaattt actttccaag
    56101 agaaatcttt ccttcccctt tttctttggc agcctgaact gctcggtaaa gtgaatagcc
    56161 actaaccgtt tcaaattctc gtcccaaacg tttctcttcg ctcttgcttg gcacgaccgc
    56221 tttgaatccc ttataggagt ccagtaactt tttagcctct actttgcctt cataggcagc
    56281 ttcaacatca ttaaaaaaag aaagcactga agcaagttct tcagtgctcc acgacaaatc
    56341 tagtgggtaa ctatactgtt tgttcattaa ctaataccag ctctcattct tgcttctttt
    56401 agttcttgct tacgataact acgagggaga aaagcacgaa tctcatcttc attaaaaccg
    56461 atttgcatac gcttggcatc aataataatt ggacgacgca aaagactagg atactgctca
    56521 atcaaatgaa gcaattccga taccgaaata ctctctacat caatattcaa tttttgaaaa
    56581 atttttgaac gagttgaaat gatgtcatca gtaccatttt cggtcaagga aaggatgtgt
    56641 tgcaattctt ttcttgttaa aggactggtc ataatattgt gttccacaaa gggaacctta
    56701 tgtttttcta accaggcctt agccttacga catgatgtac agctcggtga tagaaatagt
    56761 gtaatcatgc ttttctcttc ttatctatac tttgctactt ctattataca aaaaaataaa
    56821 gcgcttgact agggattttt agaaaaaaag cctatttttt caagaaaaat aggctttttg
    56881 cgaacgattg acacaattgg atttggttaa ttcactctta acgatggttt taaacgatat
    56941 atatttttat atatgtaaat taaaaacatc tttcctttca cttcctacga cttttcagat
    57001 acagatagcc aaagaagttt tcatagaggg caaaaaagag gaggaaggca tgaagaaaga
    57061 aggtctctgg caaaatcata ataacaggat ccttggctgg atcaaaaagc caggtatcat
    57121 ctcccacaaa gagaatttga tggaaaagag taaagaattg gtcaaaacca atcaaaactc
    57181 ccccaagtcc aatcatcaca ggtaagacta ctagagccag gagacttttt cgataaagag
    57241 acaaaaagtc ctttttcaca atcctattga caaagacata gaaacttggc agtgtcacta
    57301 gagctactag ctgaaccaaa tgaaagagat tcttgaccac tgcgaaatgg tgcagaccag
    57361 ctgctgacga acgaaaatca ggcatctgta agacctgact aaaaggattg gtcagataat
    57421 tcatcaagat atgaaaattg tattgaatgg tttctggttt tagatagact cgattcgtta
    57481 agtttagcca ctgaatctcc ataggataga aaatccaagc cagataaatg gtcagaagga
    57541 ttgagaggga gaggagaaag agcatagagc cccaaaaggt caatttagtt ttcatcaaaa
    57601 tcccactccg caaggctaga aaccacatgt gtcggtgcga ttggcaggcc agctacttct
    57661 tctgccttag taaaacctgt cgtcaccaag agcgttggaa tgccattgtc aatcccagcc
    57721 cggatatcag tcaaataatt gtccccaacc atgattaact cttcacgttc caaacctaag
    57781 tgctcaaccg ccttgtccat aatgatggca tttggttttc cgatataaac cggcttcact
    57841 cgtgtcgcta cttcaagcag cgtaatcagt gagccagcac ctggcaaaag accacgttcc
    57901 gtcgggatgt tgaggtcagg attggttccg ataaaatggg cacccttttg aatagcaaga
    57961 gttgctgtgg caaatttttc atagtcgact tgccaatcca gaccaactac cacgtaggca
    58021 gggttttcct tgtcttccac ataaccagcc gccttgatgg cttccttgag tcctgcttct
    58081 ccgacgacat agacagtctt ttcaagcccc aaatcattca tatagtcgat ggttgccaaa
    58141 gtcgctgtgt agacagtcga tagaggcgta tcgatattaa aattctgagc caacatctcc
    58201 ttaacactct ctggagtgcg ggttgtattg ttggttacaa agagataggg aatgtcccgc
    58261 ttttgcaatt catgaacaaa agtctctcca gcagggattc ggtctttccc cttataaatg
    58321 gttccgtcta aatcaattaa atagccttta tatttcatct atttctccct aaaccttttt
    58381 tatttcttgc caagtaatga ttgcttgggc attgataacc ccatcacttg taatttcatg
    58441 cttgctttcc agtccagtcc gttcaacagc cgatgtaatc accccacctg gtcgaacttc
    58501 cttgacatac ttgaggttga ttttcttggg aatatagtgg gtcaaaaaat ccgctcccat
    58561 gacctcaaaa atccagtcca agtatttact gttattgaca tgaccattca tatccaagtc
    58621 gtaaaaacga acatggtaat ccttgctgat cggctcttcc aaggattcat acttcggtcc
    58681 acggataagt tttttatcaa aatcagactg gtaaggagcc acaatctcag gttcaacagc
    58741 atggactttt cgactgtcgc ggtccatgag aacaaaggtc gccatcatat ggatgagctc
    58801 ctgccccgct tcattataaa tagtaaagcg acggtagcaa aaaagtcgat tgtagctcaa
    58861 ggcttccgtt tcgatggtaa tttcttccgc aaaacgaggc aaacgaacca cctcaatatc
    58921 atattctgcg ataatccaga ccagattata gtcttccaaa atggccttat cactaactcc
    58981 cagttcaatc gattgcatcc ctgaaacttg cagtgacagc aaaatcacat ctggaagttt
    59041 gatatgaccg ttcatatcag ccatatcaaa aggaattttc attttcattt gataagttaa
    59101 gcacatgatc ctactccaaa ataaatcgtt ctgctacagt atctcccaaa aagagacctc
    59161 tctttgtcat gcgaacgtgg tcaccctcaa tctgcatgag gccttgttga accaaatctc
    59221 tgacaatttc tccataaagt ccagcaaaag actgtccaaa tttttcctca aatcgcgcca
    59281 tggaaacccc ggatttcttg cggagtccca agaacatttc ttcttccatt tgctcctttt
    59341 gactcaggtg atcttctgta atacaagcat tgccttcctc aaccgcactg agataatgac
    59401 gaatgggacc atgattttta tagcgtactc cattgacata accagatgcc cctgcaccaa
    59461 taccatagta ttcagcattg tcccagtaca tgagattgtg acgactttca aagccgggtt
    59521 tggagaaatt agaaatctca taatgctcaa aacccgctcg ctccagctct gcaatgatgt
    59581 actcaaacat ctccgcttct agttcctcct taggcagagg caatttccca cgtcgcatcc
    59641 ggttcataaa gaccgtatgg ttttctaaaa tcaaactata caaactcatg tggggaatat
    59701 ccagtccaat ggctttagcc acattttcct ttacttgctc catggtctga ccaggcagag
    59761 cataaatcaa atcaatggag atgttgtcaa aaccagccag tttcaggcga tcgatatttt
    59821 cataaatatc cttctccaaa tgactgcgcc caatcttttt caacatctta tcatcaaagg
    59881 tctggacacc tagcgaaaca cgattgacag ccgaattttt caaaacagct atcttatccg
    59941 catccaaatc gcctggattg gcttcaatgg tcaactcttc caagacagac aagtccaagt
    60001 ttttagtcaa gccattcagt aacacctcca gttgcggagc cgacagggct gtcggtgttc
    60061 caccaccgat ataaagggtt gacaactttt caatatcata agaacgaaac tcttccagca
    60121 gatgctctaa atagctgtcg actggctgat ttttgatgaa gacctttgaa aaatcacaat
    60181 aataacaaat ctgggtacaa aatgggatgt gcacataggc tgacgttggt tttttctgca
    60241 tagtaattat tataccacaa agactagatt ccagataaaa atcaccatcc ccagatacat
    60301 agtccgtccg gagatggtga tggtttattc ttctgttata tcaatcacaa tctcttctga
    60361 gtcatcaaga gcttcggctt tttcttgcca ttgctccttg agattattta attgattttt
    60421 tgatgcttct gtcgcttgaa aagcatagga tttagcttga gcaagtatac tgtccacagt
    60481 gatttcacct gactcaacct gttcttttgt tttcagaaca aaatctgtag cctgctcctt
    60541 aacttctgtc agtttttcac agacttgctc cttggcatac tccggatctt ctctcaaatc
    60601 atctagaaaa tcttgagcct gactgcaaac ttgtttgccc ttatcacttg ttaaaaacaa
    60661 ggcaagagct gcacctgaaa cggttcctaa aaggattgag gataatttac ccataaggat
    60721 tctccttttt tattttttga aaaatttact tgcaagacga agagctgaca gacttgcacc
    60781 agtcttgagt gtttttgaac cagctgatga agctttcttg ctcaagacac gcgcatggtc
    60841 attgaggtct gaaacagata gagataaatc tgcaacagca ctgaagagtg gatcaatcgt
    60901 agccaccttg acattgatat catctgccaa gacattgacc ttagccaaca actcattggt
    60961 gtgatgcaag gtcacatcca catctgaagt caaggtttta atcgtctttt ctgtttcatc
    61021 gatgacacga ccaagctttt gtacagtaat gatcagatag accaaaaaga caatcaaagc
    61081 tagggcaaca agaatatatg caacttctaa catttagttt tcctcctctg taatatagta
    61141 aggggccttc tttcgatttt gataaataac gatcattata ccgagaccga taaagacaac
    61201 tgacagccat tgggacactc gaaggctgaa gaacatgaga ctatctgttc gcataccttc
    61261 gatgaccata cgaccgaaac cataccaaat caagtaaaag gccgtgatat gacctcgtct
    61321 gagactcttc catttccgtc taaaaatcag aatcaaggca aagccaagca gattccatag
    61381 agactcataa aggaaagtcg gttgacggta gctcccctca atatacatct ggtcacggat
    61441 aaagccaggt agataatcca gattatccac tgttgcacca taagcttctt ggttaaagaa
    61501 attaccccaa cgccccaaac tttgagcaat cataacgcta ggcgccgcaa tatctagaaa
    61561 atcccaagta ttgatgagtt tacggtcagc aaagatatag agcacaagag ccccagttat
    61621 caaaccaccg taaatggcca aaccaccatt ccaaatggca aaaatctctc ctaaattctg
    61681 actatagtaa tcaaatcgga aaataacata gtagagacga gctcctaaaa tagccaaggg
    61741 aaaggctact aagataaaat ctaaaatatc gtctggtatg atcttctttc taggtgcttc
    61801 tttcatggtc aaataaaccg caagaatcaa gcctgtcaca atacataagg cataccaacg
    61861 aatggctagg ggtcctagtt gaatagcaat tggatcaagc attttgcacc tcatttcgag
    61921 ctatgagact tgtcagtcgt tcgtcgaaca aacgggtagc atcaaagccc atttccttgg
    61981 cacgataatt catggcagct gcctcaatca caacagagat attacgacct gttttaactg
    62041 gaatacgaat acgaggaatg gctacgccag aaacttcaag ttcctctgca ttgtttccaa
    62101 gacgatcaaa ggtcttatgc gtatcgtaat tttccaaata gacagcaagc tgaacctgtg
    62161 aagaatcctt gacagcactc gcaccgtaga gactcataac atcgataata ccaaccccac
    62221 gaatttcaat caagtgtttc aaaatttcag ctggttcacc ccagagagta atctcatcct
    62281 tggcaaagat atcgacacgg tcatcggcta ccaaacggtg accacgtttg acaagctcaa
    62341 gacctgtctc gctcttacca attccactat ctccctgaat caagacgccc atcccataaa
    62401 tatccatcaa gacaccgtgc acactggtac gttctgccaa acgagaatcc agatagctag
    62461 ataactctcc agataaacga ctggtagctg cacggctggt taaaatagca atcttacatt
    62521 ctctagcagc ctttaacatc tcctctggaa ccaccaaacc acgggcaaca atgactgctg
    62581 gtgtctcagg tagaaacatt tttttcaaaa cttcataacg gctgttggaa ggcatgctga
    62641 tcagataaga ccactccttc atccccaaaa gttgaatccg ctctggtgta tagtagtcaa
    62701 aatagcctgt catttcaaga ccaggtcgcg taatatccgc tgtattgatt tccttttcaa
    62761 gcaattctgg ttcaccatag acaatatcta gtctaagctt ttcaatcact tcttttacta
    62821 aaaccgacat catttcctcc ttcaaatgaa ttcttctctc tattatatca aattgtagga
    62881 ggaagtttca gatttttgca ggctttggag tatttattta aaagaaaaag gactagattt
    62941 ctctagcctt tcatttcaat tagaattttt tacgtttacg agctacttct gatttacgtt
    63001 tacgttttac agaaggtttt tcatagaatt cacgtttgcg tgtttcttga agagtaccag
    63061 ctttagtaac cgcacgtttg aaacggcgaa gtgcgtcgtc aagagattca ttcttacgta
    63121 ctactgtttt agacattttt ttcactccct tcaagttcaa tatctatttc attctacacg
    63181 taaaaggaat aattgtcaag caaaaatgcg gtttaatttt gattttttct tccatttata
    63241 caagagttga aagcgttcaa tagaacattg cttttttatt tttcgagtaa gctaagcgct
    63301 tcagcatctg cgatgatggt tacatcaggg tgattttgga ggctacttgc aggtaggttc
    63361 tcagtcactg ggccagatac tgttccggca atggcttctg ctttcgactc accataagca
    63421 aaaagaataa tagacttggc atccaaaatg tttttaatcc ccattgaaat agcttgggtt
    63481 gggacgtctt caatcttggc aaagaagcga gcattggctt cgatagtaga ctggtcaagt
    63541 tctactagat gcgtttgact gtcaaatgga gtaccaggct cattaaagcc gatatgccca
    63601 ttgcgaccga ttcccaagat ttggaggtca actggatggt cagccaaaat ttggttgtag
    63661 cgttcaactt cagcttcagc attgtcctta acaccacgag gcaagaaact ttctttaaat
    63721 ggtttttggt tgaacaagtt ttcttgcatg aagtaacgat aagactgtgg attgtcccca
    63781 tcaaggccca catactcatc aaggttgaca ctggttagat ttgaaaaatc aaggtcactc
    63841 tcaacaattt ccttgtaaaa ttcaagtggg ctacttcctg tcgcaagtcc tagagtttga
    63901 gctccattag ccaatttttc cttcaaaatc tcaaaagcaa cttttccacc ttgaacttgg
    63961 ttttcaactt taataacttt catcttttca tcctccattt ctgtctatat ttattatatg
    64021 gtatagacca atttttgtca agtgaaaacg atttaatttc taaaaaaaga gcgtccaaac
    64081 ttgaaacgtg ttataatgga taggattaga acttagaaag aatgaacaaa tatatgaata
    64141 cagctgattt tgatttccac ttgccagagg aattgattgc ccaaacgccc cttgaaaaac
    64201 gtgatgcctc caaactcctc atcgtcaacc gtgagacagg agaaatgcaa gataaacatt
    64261 tccactctat tattgatatg ctggaacctg gtgatgccct tgtcatgaac gacacccgag
    64321 ttctccctgc ccgcctctat ggtcaaaaag tggagacagg aggtcatgtg gaacttctcc
    64381 tccttaagaa cactagtgga gacgagtggg aagttctggc taaacctgcc aaacgcctca
    64441 aggtcggtac tcgtatcagc tttggtgatg gccgcctcag cgctgtcgtt acagaagaat
    64501 tgacccacgg gggacgcatt gtccgctttg aataccaagg aattttccta gaagtcttgg
    64561 aaagtctggg agaaatgcct ctgccacctt atatccacga aaaattagat gaccgtgaac
    64621 gttatcaaac cgtctacgcc aaggaaagcg gctctgctgc agcaccgact gctggtcttc
    64681 acttcaccaa agaactgctg gcagaaatcc aagctaaggg tgttcatcta gtctatctga
    64741 ctctccatgt cggactcgga acctttagac ctgtttctgt ggataatctg gacgaacacg
    64801 aaatgcactc agagttctat caactttctg aggaagctgc tgccaccctt cgctctgtca
    64861 aagaaaatgg tggtcgcgtc atcgctgtcg gaaccacttc tatccgcacc ttggaaacta
    64921 ttggttccaa gtttgatggg caaatccaag cagattctgg ttggaccaat atctttatca
    64981 aacctgggta tgagtggaag atcgtggatg ccttctcaac caacttccat ctgccaaaat
    65041 caactctggt catgttggtt tctgcctttg caggccgtga attagtctta gatgcctacc
    65101 accatgccat ccaagaacac taccgcttct tcagttttgg tgacgccatg tttatttatt
    65161 gagaaagaat ttctctaatt cttctaatac caataaatcg ctaagatatt atttcaaaga
    65221 acatctacaa ttgaaactct agctagctgt agaagacgcc tagtacattg aaattaaaat
    65281 gcttccccct agcttcgaaa atattgccat agattgcgtt gactctccaa attgattcat
    65341 ctatatttta tttcagcttc ctatattttc ttcgctgttt gtaaatcaaa atgcaagaca
    65401 catgagtagc accatatttg ttactcttat ctgtcctctc aagagactat tatgagttat
    65461 ttcagaatca ttcactactt tgaccctgac tctccttagt ctcaaaatca aagacttata
    65521 ctcttcaaaa atctcttcaa accgcgtcaa cgtcaccttg gattatatat gtgactgact
    65581 tcgtcagttc tatctacaac ctcaaagcag tactttgagc aacctgcgac tagttttcta
    65641 gtttgctctt tgattttcat tgagtattaa acaaaaagtg aacaaatctg aattctaatg
    65701 tacagaagac taggcttgtt cactttttta tagtcgctat aagatgacct tatctatagc
    65761 tttttatata taattatata ttcagacata ctattatcaa ttttgtcgca gggaggaatc
    65821 tgttaacgca cccattcacc attatcattg actctatagc catctatact tgtattgacc
    65881 gctaactcac ccgatgcatt tacataatac catttaccac caacttggaa ccattgattg
    65941 actttcatag aaccgttgct gttgaggtag taccatgaac cattaacttg tacccaacct
    66001 gttgccatgg aaccatcagt attataaaaa taccacatac cattttcttg tttccagtct
    66061 gttgttggag caactgcttt agctggttct actgctacat ctgttccttg gttagatgta
    66121 acagatacag gatacgaagg aatagatgat tgctcaggaa caacaacttt ttcaggttct
    66181 ctcgtccctc tccttatacg tctttttacc atctctttag taatttgacg agaagtagtt
    66241 tcttcaatta ttccatcacg ttcatctaca gtatagattg tagtaagagt aatttaccaa
    66301 tttctcctac ttcttctact tcttgacttt tatcaagagt tgggccatcg agatattctg
    66361 tttcgattgg aatttcttgg acaagaactt ggggcttggt tcctttttta acaactcttg
    66421 tttgagagtc tttttttgac ttaaagtact ctcagttact tgtccactct ttccatctac
    66481 attataagtt atcgttgtaa ctgttttccc attctttcct agagtaatct cttgctcctg
    66541 tcctgcagaa aggtcattgt ctgcttcata tttagtagca aatggaacaa gaacttcttc
    66601 aatcttgctt ttagctggaa ctttgataac tgtatccgtg gcttcttttc tatcaacagt
    66661 aacctgttcg gtaacataac cagtctctgg attaacatcg taggtccttg tcgtagttac
    66721 atagccatcc tctccgtcaa ttgtaacagg attttcacta cggtcttttg tttcatcttt
    66781 ttcaaaacga attcgcgtac ttgaaatttt cttggttact accttaggtt tagtcgctac
    66841 ttttacaata atatccccat tgtcagcgtc atcatactct attccctctt ctttatctct
    66901 agtatcatct ctgacatatt gaatcccatc agcagcatga gcaaaacttg tattcagatt
    66961 cctcctaaaa ataaagttag cccgattatc gcagaaccaa aaatctttcc gagtttacgt
    67021 attgcataac gcttattagt attagatttt gccattacat cctacttcta gtatagcatc
    67081 ttttctatca aacgttaaac aatatacttt atatataaaa tagacttaga atgatatatt
    67141 gattattgaa ctaacacttt aactatatcg taatcaatct catatataaa ggattgcaga
    67201 catctgatct aaatacatgc taatatattt agatacaaac attccaactt gataattttc
    67261 actcatcttt caacattcct tacacaacga tgcagtataa atagaatagt tttctcatca
    67321 gaatgagact attttaatat tagataattt gatagaaaaa cataaataaa attggttgaa
    67381 tttaattccc taactcgata gaggattcta ttttaaattt aacaacagct aggattacac
    67441 tataaaaagt acattaccac ctgttcggct ggagaatcta gtcgattagc tccctcttag
    67501 ttacaagctt aaagcgattt tttaactaat actaaaccag attaaagaag gaactagaac
    67561 atctgtcttg tactaatcaa tatgctattt taaaattgca aataaacttg gaatgctaat
    67621 tattatattt acaataaata gttgacttcg atagaaacag aaaatagaat tcaacattct
    67681 tccctactta taccataata aataagatcc gcaagatagc cttttctctc tacaccatta
    67741 acaatggttt gtagatagga cattccagcc ttttccatga cacgacctga agctgggttg
    67801 agactggcat aacgtgctct gaccttttga aaacctgctt gagtaaaaca aaagtccaag
    67861 acagctttca aggcctctgt catcatacca tgtccccagt aagccttgcc tagcacatag
    67921 ccgatttcac agcttaaatc agcctcgtct atcttaacga tgctgatatc tcctatcact
    67981 tgctctgggt tttcttttag acaaatggcc catttgtaat agttgagatt agtataggaa
    68041 gcaacccaat tgcgaatcga gtttcgagtg atttcgacat caggatgggg atcccaggta
    68101 acataggtca gattctcagt ggatgaagcc caattttgaa acatggcttc tgcatcactc
    68161 tccacaaatc ttcttaaaat caaacgttct gtctgtaata tttgcgtacc gatagatttc
    68221 atgatgctac ctcacttcct tatttctata ctcgtagtaa gaaggctcaa ctcagtaaca
    68281 gctagaaaac gagtttgtct tctaatttct tgacgcagtt gctgcctggt ttgaaatgcg
    68341 ctctagcaag ctttttcaaa cctagtcatc gttgcagggg taagacgatg aaatcgaact
    68401 cttcgagtta ctgaatctgc ctcattttct tatttctaaa ctcggggttc aagatccccc
    68461 agaccttctc tcactttctt atttcaagat gagaggctga aaacctccac tggaggtttt
    68521 tcttgctttt taatttcagg gcaagaagct aaaaaggtcc cccggacctt cttcgctttc
    68581 tcatttctag gctcagggta aaaacctcca gtggaggttt ttactcccaa aagtcatcaa
    68641 atacagtgat gggtaagtgg cgtttgtgtt ggcctttgtg ccaccagttt tcaatggtcg
    68701 cttgagcttc tgggctgatt gttttgcctt ctaggtagtc gtcaatctct gcgtaggtga
    68761 ctccaagtgc gacttcgtca gctaggcctg gtttatcttc ttctaggtct gccgttggga
    68821 ttttttcata aagggctggc tctgcgccaa gtttctgcaa gagctgtttt ccttggcgtt
    68881 tattgaggcg gtaaagaggg agaatatccg caccgccgtc accaaacttg gtaaagaaac
    68941 ctgtgatatt ttccgcggcg tggtctgttc caatgaccgc tccgctatgg gaaccagcaa
    69001 gggcatactg agcaatcata cggcaacgtg ccttgatatt ccccttgttg aagtctgaaa
    69061 caggactacc tgtcgcttca actgcagctg tcatggcatc agctgattcc ttgatattca
    69121 caaccaagct gacatctggc tggatgaagg ctagggcttt ttgagcatct gcttcatcag
    69181 cttgcactcc gtatggcagg cggacagcga taaatttgta gctatcgtct cccgtttcag
    69241 ctcgcagttc ttccatagct aattgcgcca aacgtcctgc caaggttgag tcttgtcccc
    69301 cagaaatccc tagtacaaag gtttttagga agggatgttt tttcagatat ctttttaaga
    69361 aatcaataga acgacggatt tcttcctggg catcaatcac tggtttgaca cccagctctt
    69421 ggataatcgt ttcttgcaaa ctcattcttc ttctccttca ccaagggctt ccttgcgcat
    69481 cttatcaatc aagtccatct tatcttgcca tacatcacgc gccaaatcca ctggatagtg
    69541 ctgcggattg agcacacgct tatactcatc ccacaacttg tcaaattcct tacgggcata
    69601 atcctgaatg tcagtcaaac taggcaagtt gtaaactaat attccttctt tgaagatatc
    69661 caccaagaga ggaacggcat caaaattacg aaccgtcttc ttgatgtatg tataggtcgg
    69721 atggaacatc ttgatttctg tcatgtcgct aatatccaca ccatcataag tgatgtagtc
    69781 accttctgac ttgccttttt cacgactggt aatgcgccac acctgcttct tacctggcgt
    69841 cgacactttt tccgcattat tagacagctt aatcgtattg cgcatctggc cgttttcatc
    69901 ttcgattgca acaatcttgt aaaccgcccc aagagccggc tggtcatagg ctgtaatcag
    69961 cttggtaccc acaccccaga catcaatctt ggccttttgc atcttgaggt taaggatggt
    70021 attttcatct agatcattag aagcataaat cttagcctct ggaaatccag cctcgtccag
    70081 ttgctgacgg actttcttag aaatgtaggc aatatcccca gagtcaatcc gcacacccat
    70141 aaagttaatc tgatcaccca gctcacgcgc cacctgaatg gcagctggta caccgatgcg
    70201 aagggtatca taggtatcca caagaaagac acaatttttg tgggtcgcag cgtaagcctt
    70261 gaaagcctca tagtcattgc cataaacctg taccaaggca tgggcatggg ttcccaaaac
    70321 aggaatgtca aagagcttac ccgcacgcac gttgctggtt ccattggcgc caccaatcac
    70381 cgctgcgcgt gttccccaga tggccgcatc catttcttga gcccgacgtg tcccaaactc
    70441 catcaagggt tcatcttcga taaccgaacg aatacgagct gccttcgtcg ccaccaaggt
    70501 ctggtagttg acgatgttca aaagagccgt ttcgaccaac tgacattggg ctagaggtcc
    70561 ttccacctgc acaatcggtt cattagcaaa aaccaaatcc ccttcttggg cagaacgaac
    70621 ggtcaactcc aacttgaaat tgcgaaggta atccaagaac gccccatgat aaccaagcga
    70681 ctccaaatag gctatatcac tatctgaaaa acgcaagtct tcaagatagt tcacaattct
    70741 ttccaaacct gcaaaaaccg catagccgtt cttaaaaggc tgttggcgga aatacacctc
    70801 aaagaccgcc ttcttattgt aaatcccttg atcaaagtaa acctgcatca tgttgatctg
    70861 gtacaagtcc gtgtgcaatg tcaaactatc atctggatac atacttttcc tacttcctta
    70921 gctagaaacc catgaaaatt ttcaagaact ttcatgtatt ccaataaatt agtactatta
    70981 tatcacattt tagctggatt gagaaaagag taacaagcta ttctccactc tccaattcat
    71041 ccatatcttg ttcaaatttt ttctgagccc attcgccata gctcttaaga ccaagattgc
    71101 caataaagac ccacggaagg taaatgacat aagtaatgac ccaagcagac aggtatttaa
    71161 aattcaaagg attgtgctga taaatttcta tgttgaattg ataattctgc aacatcaaaa
    71221 gagccgtaat agccaaggtt aggaaaaaac aacccaaaat cgtaaaatga aaacgactat
    71281 agtaggtcac tcccagataa cgggcacgat tgaaaaagta aaatgtccct atgatgataa
    71341 cgattagcag catattagaa ttaaaaaggc ttggtgctaa tactgaaatg atataagata
    71401 ggagcgacaa agcaatgcag atatagaaac tttcagagcc cgctttattg aacagttgtt
    71461 cttctctttc gtctagtaat tgataataat aaaatctatt tttcatcttc ttcctcccaa
    71521 aatagttggt ctagggtttt ccctaaacat ctgcaaatag actggcagag cgagagactg
    71581 ggattgtatt ttcccgcctc tatcaaacca atagtctggc gtgtcacccc gacagcctct
    71641 gccagttgac cttgtgttaa atcacgctct acccgagcta attttaattt taaattttta
    71701 gccaccttcg tcctccttat agttttaata ctcatctact cttaaaaaat ccaaaaccaa
    71761 cacaagctat cagctattta ttataacccc attaatttgc actccagtat tatcttcagc
    71821 cgaaaatcag tattttaggt tgtttgaaat aaacttccta gtttactctt ttatttttat
    71881 ttagtattag ctttagtagg atcttttaaa cgagttttta ttgcttatat ttcttgttta
    71941 gtttagttgg tttcatatca ctattatata atgcttttgg aaatgagcct agtataagtc
    72001 aaaaacgtgt tgaatagtga aagcaggagc ataccaagat gactgatttt ttactgtatt
    72061 ttaggtatgc aaaataatac taaatgaaac taaaatgaat acttcttgct tttcttgaga
    72121 gtgaaaaagt acaataaaat gattgtagtg attagcacaa gatactgact aatagacatc
    72181 gtatttgaag ccacaaatac aggtaaagaa taaaaaggaa gaagttcaat tgctttgata
    72241 aacaaatcat tactagtatt catcatcatc gtatttaata tattagggat aaagagtagt
    72301 aaagctacta aaataccaaa taccaagcca cttttcaatt tgtataaata gaaaatgtag
    72361 gataatagaa aataaaacag gactaacaaa attgtattga ctacaatagc tactataaaa
    72421 tctaatccta aatcacctgg aatacccaat ttacttacta tgactagtaa cacaatgcca
    72481 ttccaagcat aaataatgga aactgagatg gcatatagaa aattagacaa gacgtaaatc
    72541 atccgattct tctgttgatt ataaaacaaa cttaccgtat tgtgggaaaa atctctacta
    72601 atgactcgat tagcatgtat aacagccatt aacataccga gcatggcata aaagtttgaa
    72661 atatgcttaa taccaagcga tgtcccttga gtctttagaa taaagaatgt aagcaatatc
    72721 ggcggtataa acgagataag caaactgaga tatattacgc ctgatgaata taaatttctt
    72781 atactttcct taagaaaatt caatttattt aatttcatga ttataacctt cctttatttt
    72841 gaacgattta ggtaaatatc tttaagcgtc tcttttttag tttcaaaatc aactacttta
    72901 atagagtttt cgttaaaaaa tttaaaaagc tcactacttt gaatattccc agacatagta
    72961 attctcagtc cctcttcctg aacaatatct ccaaattctt gtttggtaat gaaaatgtct
    73021 ctatctgtag ctgatgaaaa agctatctca aacaagaaat tatgactatc ttttcctact
    73081 ttttgaaatg tcaaaagccc gctctccaag aaaagaaccc tctcacaaat ttcttcaata
    73141 tcttctaatt tatgactcga tattaaaatt cccacatttt catgtaaagc taaatttttt
    73201 agaaccgcta aaactatttg tgatgattca atatctaaac cattagtcgg ttcatctaaa
    73261 atcaatatat caggttccgt aacgagagtt agaagcaaag ctaatttttg ttttgtaccc
    73321 aaagaatagg tctttacttt tttattaata gactgagtca aatctaactc ttggatcaaa
    73381 cttctaaatc tttcttgatt gtagtcaaca ccatataaat ttgacaaata ttttaaattc
    73441 tctaaacctg ttttagataa aaataatttt ggttcttcga ttaaataccc aatattatca
    73501 ctgcttataa tattacctga agtcggttga ttattctgag caagaatttt catcaacata
    73561 ctcttaccaa ctccatttct ccctactaga ccaacaattt cacccttgtt aagtgcaaaa
    73621 tttatgtctt tgagaatgat tgaatgacca taatgcttac ttacatttat aacttacatt
    73681 ttttattcct ccattaatat tcatggtttg ctctttgatt cttattgagt ttaaaaagtt
    73741 gcgcctcttt ttaacaacat tatatcatat atctaactta atgcaatata taaatatcat
    73801 tttgtaaaat tttattaaca aaaaactctc tacaacaaaa taatagagag ttttctgctt
    73861 attaattttt ttcaaaatat ctaagacatc acttctttgt ttaatttgat aggctttgat
    73921 acctaagctc cgactttatc acttaaaaaa taaaaaagga cagctaatct cttgcgcatc
    73981 aagggatttc gccattcttt aatctcgttt aagtgttgta tatggagctt tgcataattt
    74041 tttaaaacta aacaactaca ttaagcacga actgtgacgc tggttccatc ttccttataa
    74101 a
//
LOCUS       DAVKMJ010000003        72658 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000003 DAVKMJ010000000
VERSION     DAVKMJ010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 72658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72658
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.003"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(405..1601)
                     /gene="tuf"
                     /locus_tag="VW348_000165"
     CDS             complement(405..1601)
                     /gene="tuf"
                     /locus_tag="VW348_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU9745151.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2512..3381)
                     /locus_tag="VW348_000166"
     CDS             complement(2512..3381)
                     /locus_tag="VW348_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU9745152.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTENPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3605..4213)
                     /locus_tag="VW348_000167"
     CDS             complement(3605..4213)
                     /locus_tag="VW348_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEU9745153.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPEKPIPQPNPEHPSVPTPNPELPNQETPTPDKPTPEPGTPKTETPVNPDPEVPTYE
                     TGKREELPNTGTEANATLASAGIMTLLAGLGLGFFKKKEDEK"
     gene            complement(4171..5277)
                     /locus_tag="VW348_000168"
     CDS             complement(4171..5277)
                     /locus_tag="VW348_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEU9745154.1"
                     /translation="MNIILIAKLLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGRQEKLVESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5388..5642)
                     /locus_tag="VW348_000169"
     CDS             complement(5388..5642)
                     /locus_tag="VW348_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745155.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPTWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(5982..6428)
                     /locus_tag="VW348_000170"
     CDS             complement(5982..6428)
                     /locus_tag="VW348_000170"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9745156.1"
                     /translation="MDETGIDRYLYRPYAGAPRGEKVYEKISGRRFERISIVAGQVDG
                     EFIAPMIYKKSMTSDFFVEWFKTQLLPALKTPHVIVMGNAGFHPKNILDELCIQDKHF
                     FLPLPPYSPDLNPIEQAWAILKKKVTDLLREVPTIFECLECFFKTR"
     gene            complement(6501..6826)
                     /locus_tag="VW348_000171"
                     /pseudo
     CDS             complement(6501..6826)
                     /locus_tag="VW348_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331855.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7060..8778
                     /locus_tag="VW348_000172"
     CDS             7060..8778
                     /locus_tag="VW348_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEU9745157.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKITNIEAE
                     INAFVK"
     gene            8889..9236
                     /locus_tag="VW348_000173"
     CDS             8889..9236
                     /locus_tag="VW348_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU9745158.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFVGL"
     gene            complement(9515..10351)
                     /locus_tag="VW348_000174"
     CDS             complement(9515..10351)
                     /locus_tag="VW348_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9745159.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPELLKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10364..10993)
                     /locus_tag="VW348_000175"
     CDS             complement(10364..10993)
                     /locus_tag="VW348_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9745160.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11003..11644)
                     /locus_tag="VW348_000176"
     CDS             complement(11003..11644)
                     /locus_tag="VW348_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9745161.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(11790..13019)
                     /locus_tag="VW348_000177"
     CDS             complement(11790..13019)
                     /locus_tag="VW348_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEU9745162.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13009..14175)
                     /locus_tag="VW348_000178"
     CDS             complement(13009..14175)
                     /locus_tag="VW348_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU9745163.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFIAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14319..15332
                     /locus_tag="VW348_000179"
     CDS             14319..15332
                     /locus_tag="VW348_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEU9745164.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(15377..15796)
                     /locus_tag="VW348_000180"
     CDS             complement(15377..15796)
                     /locus_tag="VW348_000180"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEU9745165.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(15807..17213)
                     /gene="atpD"
                     /locus_tag="VW348_000181"
     CDS             complement(15807..17213)
                     /gene="atpD"
                     /locus_tag="VW348_000181"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEU9745166.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17299..18177)
                     /locus_tag="VW348_000182"
     CDS             complement(17299..18177)
                     /locus_tag="VW348_000182"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEU9745167.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18193..19698)
                     /locus_tag="VW348_000183"
     CDS             complement(18193..19698)
                     /locus_tag="VW348_000183"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEU9745168.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(19713..20249)
                     /locus_tag="VW348_000184"
     CDS             complement(19713..20249)
                     /locus_tag="VW348_000184"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEU9745169.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20249..20743)
                     /gene="atpF"
                     /locus_tag="VW348_000185"
     CDS             complement(20249..20743)
                     /gene="atpF"
                     /locus_tag="VW348_000185"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEU9745170.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(20757..21473)
                     /gene="atpB"
                     /locus_tag="VW348_000186"
     CDS             complement(20757..21473)
                     /gene="atpB"
                     /locus_tag="VW348_000186"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEU9745171.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNILEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(21508..21708)
                     /locus_tag="VW348_000187"
     CDS             complement(21508..21708)
                     /locus_tag="VW348_000187"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEU9745172.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(21783..22790)
                     /locus_tag="VW348_000188"
                     /pseudo
     CDS             complement(21783..22790)
                     /locus_tag="VW348_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(23211..23609)
                     /locus_tag="VW348_000189"
     CDS             complement(23211..23609)
                     /locus_tag="VW348_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9745173.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAL
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            complement(23891..24373)
                     /gene="greA"
                     /locus_tag="VW348_000190"
     CDS             complement(23891..24373)
                     /gene="greA"
                     /locus_tag="VW348_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEU9745174.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(24444..26099)
                     /gene="mltG"
                     /locus_tag="VW348_000191"
     CDS             complement(24444..26099)
                     /gene="mltG"
                     /locus_tag="VW348_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEU9745175.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGSETPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(26180..26674)
                     /locus_tag="VW348_000192"
     CDS             complement(26180..26674)
                     /locus_tag="VW348_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9745176.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(26671..27135)
                     /locus_tag="VW348_000193"
     CDS             complement(26671..27135)
                     /locus_tag="VW348_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9745177.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(27145..28479)
                     /locus_tag="VW348_000194"
     CDS             complement(27145..28479)
                     /locus_tag="VW348_000194"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEU9745178.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEVEGNDFVASDLLRSITGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(28490..29107)
                     /locus_tag="VW348_000195"
     CDS             complement(28490..29107)
                     /locus_tag="VW348_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU9745179.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVQPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(29155..32253)
                     /locus_tag="VW348_000196"
     CDS             complement(29155..32253)
                     /locus_tag="VW348_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9745180.1"
                     /translation="MAKLIPGKVRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVVVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(32346..33512)
                     /locus_tag="VW348_000197"
     CDS             complement(32346..33512)
                     /locus_tag="VW348_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9745181.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVVTFAKR"
     gene            complement(33520..34614)
                     /locus_tag="VW348_000198"
     CDS             complement(33520..34614)
                     /locus_tag="VW348_000198"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEU9745182.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSGFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDTRDLIADLRQALEG"
     gene            complement(34772..36454)
                     /locus_tag="VW348_000199"
                     /pseudo
     CDS             complement(34772..36454)
                     /locus_tag="VW348_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768988.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(36626..38584)
                     /locus_tag="VW348_000200"
     CDS             complement(36626..38584)
                     /locus_tag="VW348_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9745183.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(38787..40409)
                     /locus_tag="VW348_000201"
     CDS             complement(38787..40409)
                     /locus_tag="VW348_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU9745184.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            40515..41960
                     /locus_tag="VW348_000202"
     CDS             40515..41960
                     /locus_tag="VW348_000202"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEU9745185.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTAAYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVKRVYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMEKSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGVDCYQIIQGKKESYPGDTAVAENYL"
     gene            complement(42006..42200)
                     /locus_tag="VW348_000203"
     CDS             complement(42006..42200)
                     /locus_tag="VW348_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU9745186.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(42301..42909)
                     /locus_tag="VW348_000204"
     CDS             complement(42301..42909)
                     /locus_tag="VW348_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEU9745187.1"
                     /translation="MFGELIRYLDQYEDVILREIKAQFPDVAVDKLMEEYIKAGLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDRKYELAIDFDKERLTFYLA"
     gene            complement(42934..43446)
                     /locus_tag="VW348_000205"
     CDS             complement(42934..43446)
                     /locus_tag="VW348_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEU9745188.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACKHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERDLHDSDF"
     gene            complement(43532..44467)
                     /locus_tag="VW348_000206"
     CDS             complement(43532..44467)
                     /locus_tag="VW348_000206"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEU9745189.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRIITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(44538..44837)
                     /locus_tag="VW348_000207"
     CDS             complement(44538..44837)
                     /locus_tag="VW348_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEU9745190.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(44827..45576)
                     /locus_tag="VW348_000208"
     CDS             complement(44827..45576)
                     /locus_tag="VW348_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEU9745191.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(45630..45989)
                     /locus_tag="VW348_000209"
     CDS             complement(45630..45989)
                     /locus_tag="VW348_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEU9745192.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEKKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            complement(45991..47391)
                     /locus_tag="VW348_000210"
     CDS             complement(45991..47391)
                     /locus_tag="VW348_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEU9745193.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSIRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            complement(47686..47925)
                     /locus_tag="VW348_000211"
     CDS             complement(47686..47925)
                     /locus_tag="VW348_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEU9745194.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            complement(47957..48427)
                     /gene="ssbA"
                     /locus_tag="VW348_000212"
     CDS             complement(47957..48427)
                     /gene="ssbA"
                     /locus_tag="VW348_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEU9745195.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            complement(48439..48729)
                     /locus_tag="VW348_000213"
     CDS             complement(48439..48729)
                     /locus_tag="VW348_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEU9745196.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            complement(48882..50228)
                     /gene="asnS"
                     /locus_tag="VW348_000214"
     CDS             complement(48882..50228)
                     /gene="asnS"
                     /locus_tag="VW348_000214"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEU9745197.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVKNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            complement(50244..50609)
                     /locus_tag="VW348_000215"
     CDS             complement(50244..50609)
                     /locus_tag="VW348_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9745198.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            complement(50602..51789)
                     /locus_tag="VW348_000216"
     CDS             complement(50602..51789)
                     /locus_tag="VW348_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9745199.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            complement(51786..52274)
                     /locus_tag="VW348_000217"
     CDS             complement(51786..52274)
                     /locus_tag="VW348_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEU9745200.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGISQEKAETVSKEKGAGEIDKITFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            52595..53143
                     /locus_tag="VW348_000218"
     CDS             52595..53143
                     /locus_tag="VW348_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU9745201.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            complement(53420..54148)
                     /gene="yaaA"
                     /locus_tag="VW348_000219"
     CDS             complement(53420..54148)
                     /gene="yaaA"
                     /locus_tag="VW348_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEU9745202.1"
                     /translation="MKILIPTAKEMNTDLPSIEAISLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTTQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(54227..54391)
                     /locus_tag="VW348_000220"
     CDS             complement(54227..54391)
                     /locus_tag="VW348_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEU9745203.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            complement(54458..56053)
                     /locus_tag="VW348_000221"
     CDS             complement(54458..56053)
                     /locus_tag="VW348_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745204.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPRSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTK
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            complement(56065..56475)
                     /locus_tag="VW348_000222"
     CDS             complement(56065..56475)
                     /locus_tag="VW348_000222"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU9745205.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            complement(56591..57382)
                     /gene="yghU"
                     /locus_tag="VW348_000223"
     CDS             complement(56591..57382)
                     /gene="yghU"
                     /locus_tag="VW348_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEU9745206.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTESVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            complement(57395..60091)
                     /locus_tag="VW348_000224"
     CDS             complement(57395..60091)
                     /locus_tag="VW348_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEU9745207.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            60395..61579
                     /gene="mntE"
                     /locus_tag="VW348_000225"
     CDS             60395..61579
                     /gene="mntE"
                     /locus_tag="VW348_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEU9745208.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            complement(61722..63593)
                     /locus_tag="VW348_000226"
     CDS             complement(61722..63593)
                     /locus_tag="VW348_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9745209.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLTTLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(63590..64774)
                     /locus_tag="VW348_000227"
     CDS             complement(63590..64774)
                     /locus_tag="VW348_000227"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEU9745210.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDLDLLLQAENLRQAQGKEVNPQVIKETYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            complement(64786..65553)
                     /locus_tag="VW348_000228"
     CDS             complement(64786..65553)
                     /locus_tag="VW348_000228"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEU9745211.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            complement(65830..66678)
                     /locus_tag="VW348_000229"
     CDS             complement(65830..66678)
                     /locus_tag="VW348_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU9745212.1"
                     /translation="MKLAVFTDSSAYLSAETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASEFPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            complement(66680..67054)
                     /locus_tag="VW348_000230"
     CDS             complement(66680..67054)
                     /locus_tag="VW348_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEU9745213.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            complement(67128..68480)
                     /locus_tag="VW348_000231"
     CDS             complement(67128..68480)
                     /locus_tag="VW348_000231"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEU9745214.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            complement(68504..69283)
                     /locus_tag="VW348_000232"
     CDS             complement(68504..69283)
                     /locus_tag="VW348_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEU9745215.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            complement(69270..70127)
                     /locus_tag="VW348_000233"
     CDS             complement(69270..70127)
                     /locus_tag="VW348_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEU9745216.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            70263..71231
                     /locus_tag="VW348_000234"
     CDS             70263..71231
                     /locus_tag="VW348_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU9745217.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELESVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWTLAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFVPSQLLGDGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            complement(71483..72439)
                     /locus_tag="VW348_000235"
     CDS             complement(71483..72439)
                     /locus_tag="VW348_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU9745218.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKQDIENGLRAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKNTWYYLDAKEG
                     AMVSNAFVQSADGTGWYYLKPDGTLADKPDFTVEPDGLITVK"
     gene            complement(72443..>72658)
                     /locus_tag="VW348_000236"
     CDS             complement(72443..>72658)
                     /locus_tag="VW348_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEU9745219.1"
                     /translation="IKIVEILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKY
                     NISMTDKDLDTFVESAVKQMNDAWKGR"
BASE COUNT        21104 a        16240 c        13543 g        21771 t
ORIGIN      
        1 ttcttcttta gttgatttca tattactatt gtataatgct ttttgatttg agtctagtat
       61 tatactcttc gaaaatctct tcaaaccgcg tcagcttcgc cttgtcgtat agatgttact
      121 gacttcgtca gttctatcta caacctaaaa acagtgtttt gagcagtctg cagctaactt
      181 tctataacaa aatgaaataa gaacaagaca aatcaatcaa gacaatcaaa tcgatttcta
      241 agaatgtttt agaagtagat gtgtactatt ctagtttcaa tatattatag tttgctcttt
      301 gattttcatt tagtattagt tcaatatcta aaaaaagaac cttgccaagc aagattcttt
      361 tagtgtctga cttaaataat tgttcttctg ggaactaaat cgaattaagc ttcgatttct
      421 gtaaccatac ctgaaccaac agtacgtcca ccctcacgga tagagaatgt agtaccttgt
      481 tctacggcga ttgggtgaat caactcaaca tcgattgtca cgttatcacc aggcattacc
      541 atttcagtac ctgctggaag ttcgattgaa cctgtaacgt cagtagtacg gaagtagaat
      601 tgtggacggt agttgttgaa gaatggagtg tgacgtccac cttcttcttt agtaaggatg
      661 tagacttcac ctttgaattt agtgtgtggg ttgattgaac ctggtttagc gataacttgt
      721 ccacgttcga tttcatcacg ttgaacacca cgaagaagga cacctacgtt atctccagca
      781 agaccttcgt caagttgttt acggaacatt tcaacaccag taacaactgc tttttgagtt
      841 tcttctttga taccaacgat ttcgatttcg tcgttgactt taacgatacc acggtcgata
      901 cgtcctgaag caactgtacc acgtccagtg attgagaata cgtcctcgac tggaagaagc
      961 aatggtttgt cagtgtcacg ttctggttct gggatatact catcaactgt gttcatcaat
     1021 tccataacga tgtcttcgta tttagagtca ccttcaagag ctttaagtgc tgaaccttgg
     1081 ataactggaa gatcgtcacc tgggaagtcg tattctgaca ataggtcacg gatttccatt
     1141 tcaaccaatt caagcaattc ttcgtcgtca accaagtcaa ctttgttcat gaagacgata
     1201 aggtgtttaa caccaacctg acgtgaaaga aggatgtgct cacgagtttg tggcattggt
     1261 ccgtcagttg aagctactac aaggatagct ccgtccattt gagcagcacc agtgatcatg
     1321 tttttaacgt agtccgcgtg tcctggagcg tcgatgtgag cgtagtgacg tttttcagtt
     1381 tcgtactcaa cgtgcgcagt gttgatagtg ataccgcgtt cgcgttcttc tggagcagca
     1441 tcgatagacg catagtcttt aggttggtta actgatgaag gcaagcgacg tgccaaaaca
     1501 gttgtgatag ctgcagttag ggtagtttta ccgtggtcaa cgtgtccgat agtaccaatg
     1561 ttaacgtgtg gtttactacg atcgtatttt tcttttgcca tttgagtaaa agcctccaat
     1621 aaaatatatt ttatagatag acagtaggca atacagtcta actttcctta ctattttatc
     1681 aaatttcagc taaattgcaa gtgttttaca acgtttttgt gaattattct tggtaaaaat
     1741 ttaactaact aatagaaagt actaaataga cttatccttc aaggagtttt cagcattatc
     1801 catccactca cttgctgaaa atgtaaacag tctctggttt atatagtaaa atgaaacaag
     1861 aatagggcaa atcgatcagg acagtcaaat cgatttctaa caatgtttta gaagttaagg
     1921 tgtactattc tagtttcaat ctactataca acctcaaaac tgtgttttga acaacctgcg
     1981 gctagcttct tagtttgccc tttgattttc attgagtata aaattgcaga taaaacgata
     2041 acaatcatag gactcagcag agtcaatgta ggtcgaagaa tagcccccct aatcgcttat
     2101 tttatagcaa aatgaaatag aaactgaaca ttttgttgag gaaggtaaat caattcctca
     2161 caatgtttga gaaagaaggg aggactattc caacttcaac ccactataaa gcagacttac
     2221 aagataggga acccatctcc gataatatat agtagaatga aaactgcaca atttgattgg
     2281 agaattcaaa ccaatttcta acaatgtttt agaaacaagg gtctattatt tcaactgcaa
     2341 cctactatag cccattgaag ctggaatagc ccactgagac ttctaaacca ctgctggaga
     2401 ggagtttgtt tagagtttct ttcatttccc taaaaaatca aaaagagaga accagtctga
     2461 tcctctctta cttatagatg gtgctcactc aaatgttaaa ggagctattt cttagagata
     2521 aaggaatttg aatacagcta ctgccgcaat tgctgctgcg ataggtgcta ctactggtac
     2581 ccaagaatac caccattttg aatcgccttt atgctcacca agaactgatt ttggaaggaa
     2641 agcatgaagg agacgtggtc ccaagtcacg ggctgggttc aaggcaggtc ctgtaggtcc
     2701 tccaagtgat gttaccaaag ccataacgag gaatccaagt gccaagtgag ccacagaaag
     2761 tcctgaagca gtgtgtggag ccacctgtgc tttaatagcc aagtcagaaa aatcaactgt
     2821 ttgtcctgct tctattgcct tttgtttcat gaattgaagc acttcagcac caaagaagtt
     2881 tttagtcaaa ccaagagctg caaagaacaa aacaaatgaa ccaacaaact cattaatcaa
     2941 accattgaca gttgctgcat agcgactttc ttttgtacca tggtcaatac ttgaaatagt
     3001 tgagaaagtt cccaagatgt tatttgggtt ttcagttttc aagtagaatg gacggtatgt
     3061 tgccacaact aaggcttggc caaagatagc ccccaagact tgcgcgataa tgtaaggtac
     3121 cacttgtgcc caagggaaaa gaccgctaac tgcaagccct agagtgaaag cagggttgat
     3181 gtgattccca gatacgttac caaacatcaa ggctgggatc ataaccccca taccataacc
     3241 aacagcgatg acgatccagc cactttggtg acctttcgta cctttaagtt caacgttggc
     3301 aactgcacca ttcccaagaa tgatcaaaat ggcagttccc aaaaattcag tggcatactt
     3361 cagtgcccat gtgaaatcca tttgctagat tctccttaaa attttttaga tattccttat
     3421 tttatcaatt tttaccctat ttagcaactg atttctggaa atatttttaa aaaaatagga
     3481 ttcatagttt cccagttcaa cagacttgta agcgttttta ttctttacga aagacctcgt
     3541 tctcaaaacc aggaaaaaag cccacatctg tgagcttttc ctggttccta gattctaaaa
     3601 tctattattt ttcatcttct tttttcttga aaaatcctaa tcctagacca gctaacaagg
     3661 tcatgatacc agcactagcc aaggtagcat tagcttctgt acctgtgttt ggcaattcct
     3721 ctctcttacc tgtctcataa gtcggaactt ctgggtctgg attcactgga gtttcagttt
     3781 ttggagtacc tggttctgga gttggtttat ctggtgttgg agtctcttga tttggtagtt
     3841 ctgggtttgg tgtcggaaca cttggatgct ctggatttgg ttgtgggatt ggtttttctg
     3901 gtgttgataa acggtcatac cttaccgtta tttctttatc actagagtct gacgtaactt
     3961 cttgtgattc aactgttgga atatctggat ctttgtactt gtcaatctta ccagatataa
     4021 cctcgtccca gtttcctgtt gtccattcac cgtaggttac aactcccgtg accttgttct
     4081 cagtttttgt acggcttaag gttacaggtt gaacaacatc ttcttttaca ttttggttcg
     4141 taactttatc aacgtaatga atgatacgcg ttatagtctt cgtctcagta gaggttgctg
     4201 ttttgggaac cactgtttcc tcaacattct cacggtagta atagtcaact gttgcaccgt
     4261 cttctggtac gcatttgcag gagttgctac caaggtgtat gttgttttcc ttgtgataac
     4321 tcggtcttct ttgtcctcag ttgttgtttt cccttcaata gtttttgatt ctgtggtata
     4381 ctcagaacct atcgctaaat cagcttttat aacagactct accaacttct cttgcctacc
     4441 ttctttatag taattggctg ttactgtagc agtggttggc gcttcgcttt ctctataaac
     4501 taaggtcact gttctacctt cgcttacaat attcccagtt aaacttgcag aatttgtatc
     4561 tgcttcttta aaagtataat attttccgtc agtagtagtc atgctactga gttttttatc
     4621 tgtgacattg tagctggtac caatcagttg ttttttattg gtaatgtagg ttccgtcact
     4681 ttctttttct ccaattccag tatcattttt caatgatagc aaacgccctt gttcatcaac
     4741 atagcgaact ttcacatttt ctgagattag ttctgccaat tctgaggttt ttttcttttt
     4801 cttgatttct tcggttattt tccctttctc ttcttcggga atatttagtt ttggaatgat
     4861 tttttcaaca acggttcgtg atggttccac agtatcttgg atgactgaaa agtcagctag
     4921 aattgggaga ttatactgaa cacggtgact ttgagtgttt actcctactc tttcattatt
     4981 ctctgaaaat acttgtacgg tataagaaac aacatctttt cctaatagaa catccccagt
     5041 agagaaatag ccgccttttc ctagtttgct atctccagag cccacttctt tcctaatctt
     5101 atcagatagt tttttaccag tcagtacatt cgttcgcaca atccctttgt ctacccctac
     5161 aaagtgggag aactttttga actcttcaga accagatcta gcccaaccat tattaagggc
     5221 atttgctttt gtatttgtat tctctctcaa aagtttggcg attagaatta tattcatcgg
     5281 cacttagagt tgctgctata tctgactctt gaataccaac ttccttacta ccatttctag
     5341 cggcagtata tgtgtattta tctgtttcta cttctagctg attatcctta acatgatagg
     5401 taattttctc ctggtataag agtcttcagt agtttatatg ctctgtcatc atctttagct
     5461 ttagaagcag ctgagtttag ccaagttggg gtattaggag tatctttatc agcctgtttc
     5521 aagacattat tcaagtcatt tgctagccta ttggttgtcc tcactgtgaa agttttcttc
     5581 cagtctgaac cacttttatt agacttagat atgctcatga aatcctggtc aacattcaac
     5641 acaatatcgc cttgtttttt agcatcttcc gttgcttctg cttcaaattg atcatggagt
     5701 ttttgttgct ctggtgtata gtttttttat ttacacgatt taatgtacta ttttttattt
     5761 tagtattaag aactccatta atacgatttt taaactctgc ttcaaaaaat cccttaattt
     5821 gttggtgcgc aagttcaaca ttcaaacctt ttttatacaa gtcttcattc tgaacgattt
     5881 cggctacacg gtgaatggtt tgattgtata ccgtcttctc ttaaccagca gtatccttag
     5941 ttttaatgac tactcgatag gttcctttag aaccgttata gtcatctagt tttaaaaaag
     6001 cattccaaac attcaaaaat agttggaact tcccttaata aatccgtcac tttctttttc
     6061 aagatagccc aagcttgctc aataggattc aaatccggtg aataaggtgg tagaggtaag
     6121 aaaaagtgtt tatcttggat gcagagttca tccaaaatgt tcttgggatg aaaaccagca
     6181 ttgcccatga caataacatg aggtgtcttc aaagcaggta ggagttgcgt tttgaaccac
     6241 tccacaaaga aatcgcttgt catgcttttc ttgtaaatca tgggagctat aaactctccg
     6301 tctacttgtc ctgcaacaat tgaaattcgc tcaaaacgac gtccgctaat cttttcatag
     6361 actttctccc ctctaggagc ccctgcataa ggacgataga gatagcggtc gattcctgtt
     6421 tcatcaatat aaacaggtgc taggtgcttt aaactattaa aattcttaag aaataaggct
     6481 acttttctgg gtcttgttcc ttaaagctcg tcatcttttt ttaaagtgac cttaatctgc
     6541 tttaaagctg cccatactga aggaacagca caatcaaaat gtgccgcaat ttcccgtaaa
     6601 aaagcatctg gatgagcctc tacaaaggct ttcaattcct ctaaaggaat ctttcggttt
     6661 ttgacgactc gctttttcct ctctatgtgt tcttgttcac gtctttcttt tcccacgtga
     6721 agagagttct gacgccaaca ccaaaaaact tggctgcctc gacatggctg tgcccctctt
     6781 tgatgtaatc taatgctcgc tgtttaaaat cagtactata tgccatagct ttattataat
     6841 atgcttgttt aaaactaagt aactatatca atgttttgtt atgagaagac ttactttttt
     6901 tactgaaatt gaatttttcc tagcctaaac atcatataac cccaaaattc aatctgacct
     6961 ggtttgaaga gattttcgaa gcagataagg ttttactaaa actaaaaaaa atgatataat
     7021 caaactgatt aaatgtttta aaaataaagg agaatttgaa tgtcttacca agaaaattac
     7081 cagaaatggg ttgattttgt ggagcttcct gactaccttc gtcaagattt ggaaaatatg
     7141 gacgaaaaaa ctaaggaaga tgccttctat acaaatcttg aatttggtac tgcaggtatg
     7201 cgtggcttgg ttggtgctgg tacaaaccgt atcaacatct acgttgttcg ccaagctact
     7261 gaaggattgg ctcgtttgat tgagtcaaaa ggtggaaacg agaaagaacg cggtgtagca
     7321 attgcctacg atagccgtca cttctcacct gagtttgcct ttgaatctgc ggcagttctt
     7381 gctaaacacg gcatcaaatc ttacgtattt gaaagccttc gtccaactcc agaactatca
     7441 tttgcagttc gtcatctcaa ctgtttcgca ggtatcatgg tcacagccag ccacaaccct
     7501 gctccattta acggttacaa ggtttacggt gaagacggtg gacaaatgcc tccacacgat
     7561 gcggacgctt tgactactta tatccgtgca atcgaaaacc catttgcagt tgaagttgct
     7621 gatgtggaaa ctgaaaaagc ttctggcttg attgaagtta tcggcgaagc tgttgacata
     7681 gaatacctta aagaggttaa ggacataaac atcaacccag ccttgattga agaatttggt
     7741 aaagacatga agattgtcta cacaccactt catggtactg gtgaaatgtt ggctcgtcgt
     7801 gctcttgccc aagcaggatt tgactctgtt caagttgttg aagcgcaagc aactgctgac
     7861 ccagacttct caactgtaac atctccaaac ccagaaagcc aagcagcctt tgcccttgct
     7921 gaagaacttg gtcgtcaagt tggtgcagat gttcttgtcg caactgaccc agacgctgac
     7981 cgtgttggtg ttgaagttct tcaaaaagat ggcagctacc tcaacctttc aggtaaccaa
     8041 atcggtgcta tcatggctaa atacatcttg gaagctcaca aaaacgctgg aactcttcct
     8101 gaaaatgccg ctctctgcaa atctatcgtt tcaactgact tggtaacgaa gattgctgaa
     8161 agctacggcg caactatgtt caacgtcttg acaggtttca aatttatcgc tgaaaaaatc
     8221 caagaattcg aagaaaaaca caaccacact tacatgatgg gatttgaaga aagcttcggt
     8281 tacttgatta aaccatttgt acgtgataaa gatgccatcc aagccgttct tgtagttgct
     8341 gaacttgctg cctactaccg ttctcgtggt ttgacacttg ctgacggtat cgaagaaatc
     8401 tataaagaat atggctacta cgcagaaaaa acaatctctg ttactctttc aggtgtcgat
     8461 ggtgctgaac aaatcaaagc gattatggct aaattccgca acaatgctcc aacagaatgg
     8521 aacgcaacag ctatcactgt cgtagaagac ttcaaggcac aaactgctac tgttgctgac
     8581 ggtactgtta caaacttgac aactcctcca agtgatgtgt tgaaatacac acttgctgac
     8641 ggttcatgga ttgccgttcg cccttcaggt acagaaccaa aaatcaagtt ctacattgca
     8701 gttgtagggg aaaccaacga agaatcacaa gctaagatta ctaacatcga agcagaaatc
     8761 aatgcatttg taaaataaag acctataaaa gatgagacca accaacctca tcttttttcg
     8821 tatcaaatct aagcaatttt agaaacttta tggcatacta gacttatcaa tgaaagcgag
     8881 gtaatctcat ggaacaattt ttagataaca tcaaagacct tgaagtcact acagttgtgc
     8941 gtgcgcaaga agctcttgat aaaaaagaaa ctgcaacctt ctttatcggt cgcaaaactt
     9001 gcccttactg ccgtaaattt gcaggtacat tgtcaggtgt cgtagctgaa accaaagctc
     9061 acatttactt catcaatagt gaagaaccaa gccaactcaa tgatttgcaa gcattccgct
     9121 cacgttatgg aatcccaact gtaccaggtt ttgttcatat tacagatgga caaatcaacg
     9181 tccgttgcga ctcttcaatg tcagcacaag aaatcaaaga tttcgtagga ttgtaaaaaa
     9241 tcagctaaca agtcttaaaa tcacaaaaac gcataatgta aggtgcaaaa accttgatat
     9301 tatgcgtttt attgttccta aaacagttac atcagtattt cattacagaa cattttaatt
     9361 ttggaagtca aatcaatttt taacaatgtt ttagaaatca cagtgggcta ttccatattc
     9421 aattatccag attcaatcgc tattatcgtt ttcctagatt acaaaaaaaa ctacgttttg
     9481 ctaatcaaaa cgtagtctca gccactattt tatcttactg tccttctttt acttctttgg
     9541 ttgctacatc ttctccaaac catttttggc tgatttcttg gaacttgccg tccttgtaaa
     9601 gactagaaaa agcttcattt atcttcttaa ccaaggttgt atcttcctta cgggctccaa
     9661 ccgcaaaagc ttctgtttct agtccaactg taaagacatt ataatcgttt aaaacacctt
     9721 ctgcttctaa ataatagttt gcatagacac ggtcaatcaa tagaccatca attcgatcgt
     9781 ttttcaaatc aatcaaggct tcattaaagg tttggtattg attcgcttcc ttattagcga
     9841 caatattctt caaaagttct ggatttgctt caaagtccgc ataaccagat gaaccagctt
     9901 gagctcctaa tgtctttcca gtcatatcct ttgcagtcgt gataccagat gatttcttcg
     9961 taaccaatac ctgctcattc ttcatatatg agttactgaa agccaccttt tcacggcgtt
    10021 cgtctgtagc ggaatagcca ttccaaatca gatcaatcgt tccttttgtc aattcagctt
    10081 ctttcaaatc ccaatcaatc ggttgccaat ttaccgtgat tccgtatttt tcaaaaacag
    10141 ctgtagctaa atcaatatca aatcctgcat aagaaccatc tttctgagca aatcccattg
    10201 gaacaaaagt actatcaaat ccaatagtaa tagacttgtt agactggtac tttgaccaat
    10261 tatctccact agtttcgcta gaatttttcc cacaagctac taagaacaaa gcagtcatca
    10321 gactgactaa tacaagcatc cattttttca tccatttttc ctcctattta ggttctactt
    10381 tcaataatac atctgcgata ttttcagcaa actgcaaatc atgggtaacc acaatctggg
    10441 tcatcccaag ttccctattt tgcaagatta gcttctccac ttccaaacgt aattctggat
    10501 ccagggcaga agttggttca tcgtagccaa tgatttctgg gtcaatcatc atagcacgcg
    10561 ccaaagccac tcgctgcttt tgcccaccag atagtgagaa aggataggcc tctgcgtgtc
    10621 ctcctagtcc taactgttcc aagagtccac tcgccttctt ctcagcctct tcctgcttca
    10681 ttcccatggt cttcacaggc gataaagtca aattttccag aactgataga tgaggaaata
    10741 gttgaaaatc ttggaagaca aatcccagta ggttgcgctt ctgcaattca tccagctcta
    10801 aaggttgtcc attataaaag atttgccctg aatcaatggt ttcaagacct gcaagcatac
    10861 gtaaaagagt tgtcttacct ccaccagaag gtccaacgat agccaggatt tgcttttcag
    10921 gaatacttag actgaaatta gacaggattt gtttgtctcc aaagacttta ttgatatttc
    10981 gtaattctaa catggcagcc tcctatctat aataactata cttcttctca acttttttgg
    11041 aaataattgt cacaatccca atcaaaatca aataaatggc tcctgccaag aacataggaa
    11101 ccagactagc atcgcggtta gcagctgttc gactagccaa gataaggtct gaaattccga
    11161 gagcatagac caaagaagta tccttgacca aactcataac ttcattaaag acactaggaa
    11221 gaacgatctt ggtcacttgg ggcaagataa tatagcgcac tctgtcaaaa gggctaaact
    11281 tcaagacctt ggcagcctca tactgtcctc ttggaatagt gtcaattccc ccacggaaaa
    11341 tttctgcaaa gtaagccgca taattcaaaa caaaggcaat aatagctgca ggaaggcggt
    11401 ctaaacgaat cccaatactt gggagcacat aatagataaa aatcagttgc aagagtaagg
    11461 gggttcctcg cataacccag atgtaaatgt taatcagata atggaggggc ttccaatgga
    11521 cttgcaaggc aaaggcaatc aaaacgccca agggaatcga aaatagcaag accagtgcaa
    11581 agacctgtac agtcgtgctc gcaccattca gtaaactcgg taatatctca aataaataag
    11641 acatactgca cctcctaaaa gtaattgttc ctattatagc atgaataaac aagattacca
    11701 agtatttttg taaaaagatt ctaccatata caaataaaaa ccgtagctat caaaagagat
    11761 aaactacagt tctatatgtt taaacattct tacaatctct caaacagttc ttgcatttgc
    11821 acatcatctg gaaccagttt taagtaagtg tgagcatgga cttttgcttc ttcaaaatgt
    11881 cccaattcac gcaagagata gatatagtgt tccagaaatt ctggattgtc cttcaaatct
    11941 cctgtcaact cttgataatg ctcataagca gtatccaaat cgtccatttc ttgataagaa
    12001 cgagcaatca tccacttggt caaaagattt tctggctcct cactctgcaa gtctagaata
    12061 tcctcataac gctcctgctc cagataaata gtggctaaac gaagcaagat ttcttctgta
    12121 tcctcagcgt cttcttttgc agtaaggaga taattttctg caccactagc atcatgcaat
    12181 tcataagaaa attgtgaagc agctagcaag aggcgagttt caaagggatt tttctctaat
    12241 ccttgcttag cgatacgcag ggcttcttga acttgatgtt ccttatgtaa agcctgactg
    12301 tacccatact catagccttc aaagtcagga gaaatggtat caagctgctt aaagtagagg
    12361 gtggcttttt gatattcttc ttgatcaaaa taaagactgg ccaactcaaa agctgttaag
    12421 tcatcgtatt ctaactccag ggctttttct aaaaactcag tagccgtttc aaatttccct
    12481 aactgagcat aggcaaagcc aattcgttga taggtggaaa tgcccgtttg ctcataaatc
    12541 gagcgattat ctaactgggc ataggcttga atagccgctt ggtaattttc caactcacta
    12601 tccaactctg ccaaacccaa tatcaagaga gaatcctctg agtaggtcaa ggcctccaat
    12661 aatttctcac gtgccacatc tgtcaaacct tccagctggt aaaggtctgc cttcagagcc
    12721 aaagacgaga cataccagtc actgtcagct tggatttcct caagataggt aaaggcttct
    12781 tctatttgac catcctcgct agcaattgca gctagattaa gatgaacctc tggaaaatcc
    12841 tctacaattt tcaggtaaat ttccttggcc tgaggataga aaccaatccc ttcaagataa
    12901 gttgccaact catacagaag atcacttgaa tcattttcta aagctttggc gaaataatgc
    12961 tcagccttag ttaaatcttg ctcctccaaa gcctgtaaca tctgttgact attgttcact
    13021 cttgacttcc tcaccctcta attcatatag accactgact accttatacc attcgaaaat
    13081 ggctgaaatg acaaccttag cagaggcata aaccggaata ccaagtaaaa ctccccagat
    13141 accaaacata gatcctgaag ttaacaaaac aaagagaaca ttaataggat ggatgtttaa
    13201 ttgacttccc aaaatcaatg gagagacaaa acggccttca atagtttgtt ctacaataaa
    13261 gacaatcact actttcaaaa gcatgactgg accagcaatc aaacccaata ctagggcagg
    13321 aagcatggct agaaagctac caagataagg gaccagattt aaaataccag cagtaacccc
    13381 cagcgtaacc gcatagcgta gaccaataat cttgaagaag atgataaaca ttactgctac
    13441 aataatagcc actgtcactt gccctcgaac atagttggac aactgttgat tcacatctga
    13501 tagaacttgt ccaacaggtt ccttcaattt tcttggaatg aattgggtca aatagttacg
    13561 caagcctttc ccatcacgca agagataaaa gagcatgaaa ggaacgataa tcaaggcaac
    13621 aatcacttga gaagctccgc taataaaggc actcacccag ttgactgcct gagatgaaac
    13681 cttacttgcc aaaactgtag cctggctaga aaaattggtc aaaacttgct ctaattgagg
    13741 tctgaaatca tctggcaggt gctgggctac caatccatta acaatcctat ctatatcttc
    13801 taagtaaaca ggaacgtttc ttgcaaaggt caaaacctga cgttgcagat ttggaatggc
    13861 gactgccaag ccccaaatga taaagagagc gatgataaca aagacaatag tgatagctat
    13921 aacacgatta accttatgct tctccatcca atcaacaata ggattcaaca aataatataa
    13981 caaaccagac aaaatgactg gcaacatcac aactgctata aagtctaaaa caggtgaaaa
    14041 tagaaaacta atcttactta aaataaaaag attcaatccc aataataagg ttactaaaaa
    14101 taccgtaatt gccttgttat ctaaaaacca cttgaaaaac caagataggc taaaatgttt
    14161 ctctttttgc tccataaata cttcctttct attgttctct cattatacca tttttgaaac
    14221 aaaataactc ttttttaaag tgcttacatc taattgaatg tctttaattt gcttgttttt
    14281 gtgatataat agtcttatct ttacacagag gtatagtaat gaaagaaact gtttattttg
    14341 gaacttatac acgtcgtact tctcaaggga tttacaaggc agactttgat acagaaactg
    14401 gtcagctttc aaatctagaa ctttttgcag ctgagccaag tccaacctac cttgcctttg
    14461 accagcacca acatttatac actgttggta gccaagacga taagggggga attgcagcct
    14521 atcaaactga cgggactgtg ttaaatcatg ttgttgaaga aggagctccc cactgttatg
    14581 ttgctgtcga tgaaaagcgt gatttggttt acgcagccaa ctatcacaag ggacaagtcc
    14641 ttgtttataa acgccaggaa gatggtagtc ttctacttag tgatatggat caacacagtg
    14701 gccaaggtcc acatgaaaat caagcttccc cccatgttca ctatacagat ttaacacctg
    14761 accactatct agtgacctgc gacttgggaa ctgaccaagt catcacctat gacctcgatc
    14821 aagaaggaaa attatctaag ctctatacct atcacagcaa gccaggagca ggctcacgcc
    14881 atatcatttt ccataaccac tataaaatcg cttatctcat ttgtgaactc aatagtacta
    14941 tcgaagtttt aatctacgat ggcgttggcg aatttgaacg tatgcaggtt atttcaactt
    15001 taccagaagc ttacgaaggc tttaatggaa ccgctgctat tcatctctct aaagacggta
    15061 aatacctcta cgcttctaac cgtggccatg attctatcgc agtatatacc atccttgcgg
    15121 acggtagctt agagttatta gaaatcgttc caacgcatgg tcagactcca cgtgattttg
    15181 atttgacacc cgaccaaaaa tttctcattg ttgtccatca agactctgac aatgcaactg
    15241 tctttaaacg taattgtgac aatggtcgtc tagcagaact ctccaacgac ttccatgttc
    15301 ccgaagcagt ctgcatccgt tttgctcctt aaaacaccat aaaaaatgaa cttggtattt
    15361 tcaagttcat tttttcttat agtctatttc cgacattaat acggttaata gcacgttgca
    15421 aagcaatctt agcacgacgt tcttggtcaa tcaaatgttt gtcttgtgct tcttcaattg
    15481 cacgttctgc acgaagtttg gcacgttctg cacgactgat atcgatatca cgagcacgtt
    15541 ctgcagagtc agcgacgatt gtgatcatat cattggcaat ttcaataacg ccaccgttta
    15601 ctgcaatcca gttcacgtga tctttatcat cgatacgttt tacctttact tcatcaactg
    15661 ctaaaaccgc aatcatattt tcatgtcgtg gcaagatccc catctcacca tccagagttc
    15721 gaaccgatac atagctggca tggtgatcat agacgagacc atctggtgtc acgatctgga
    15781 cagttaactg agccatagat cacctcttaa aatcccattt tttcagcttt tgcaatcaca
    15841 tcttcgatag aacctacacc acggaaggca tcttctggca agtggtcgta tttaccatca
    15901 aggatttcct taaagccacg tacagtttca gcaactggaa cataagaacc tggctgacca
    15961 gtaaattgtt ccgcaacgtt gaagttttgt gacaagaaga actggatacg acgggcgcga
    16021 gcaaccaagg tcttttcttc atcagaaagc tcatccatac caaggatagc aatgatatct
    16081 tgcaattcat ggtaacgttg aaggacacgt tttacttcag cagcaactgc atagtgctct
    16141 tctccaacga tttcaggtgc caaggcacgt gagcttgaag caagtgggtc aacggctggg
    16201 tagataccca attgtaccaa cttacgttcc aagtttgttg ttgaatccaa gtgagcgaag
    16261 gctgttgctg gcgctgggtc agtatagtca tccgctggca catagatagc ctggatagag
    16321 gttacagaac ccttcttggt tgatgtgata cgttcttgca attgacccat ttccgtagca
    16381 agtgttggtt ggtaaccaac ggctgatggc atacgaccca aaagggcaga tacttctgaa
    16441 ccagcctgag tgaaacggaa gatattatcg ataaagagaa gcacgtcttg gccttccaca
    16501 tcacggaagt attcagcgat tgtcaaacca gtaagggcaa cacgcatacg tgctcctggt
    16561 ggctcattca tctgaccaaa gaccatggct gttttctcga taacgcctga ttctttcatt
    16621 tcccagtaaa ggtcattccc ctcacgagta cgttccccaa caccagtaaa tactgaaata
    16681 ccaccgtgct cttgggcaat gttgtgaatc aattcttgga ttaagacggt tttaccaact
    16741 ccggcaccac cgaaaagtcc aactttacca cctttaaggt aaggggcaag aaggtcaata
    16801 accttgatcc ctgtttcaag gatttcagaa gaggtagaca actcatcaaa agttggagct
    16861 tttttatgaa ttggctgacg ctctgcgtct tctgtaaaag gagcttccaa atcaatggta
    16921 tctcccaaaa cgttgaagac acgtcccaaa gtttctttac ctactggtac agagattgga
    16981 cgacctgtgt ccaatacttc cattccacga gtcaacccat ctgttgattc catggcgata
    17041 gtacgaacca taccatctcc taactccaag gctacttcaa ggacgatttt tgtttttctt
    17101 tcgtcatttt tgtagacgac aagtgcattg ttaatctcag gaagtttttc ccctgctgca
    17161 aacaaaacgt ctacaacggg accgataacc tgagcaattt tacctgaact catctccttc
    17221 tcctattcta tataagatac tgtcggttcc tagctcaact aggtcctaag ttcattttca
    17281 tacgagctgg actagagcct attctaaggc actagcacct gctacgattt ctgtaatttc
    17341 ttgtgtaatc gccgcctgtc tggcacggtt atactgaatt gtcaaatcat tgatgacttt
    17401 cttagcatta tctgtcgctg tttgcatggc tgtcataccc gcagcattct cagctgtctt
    17461 ggcatcgata atggcaccgt aaatcatact ttctgcaaac tgaggcaaca actgctccag
    17521 aatttcttct cggctggttt ccaattcaaa agtcaagctg tactcttcat ccgcttcatt
    17581 tggatccaag tcaacaatcg gaagcatttg ttccacacgc atttgactgg ttagcgtatt
    17641 gacatggtgg ttgtagcaaa cataaagctc atcaaagagt tcattttggt acatttcaac
    17701 agtttttgaa ataatcttac gaacttgatc aaagctaggt tggtctgcca agccacgtaa
    17761 ttcataaagt ggttgaatac cgcgagcctt aaagaaatca gctcccatcc caccgataca
    17821 gatcatttca aaacctttac cgtctgggtg gtattcttct ttcaactcca taacagcttt
    17881 caaaatagag gaattataac ctccaaccaa accgcggtct gaagtgataa cgatatagcc
    17941 tgtcttcttc acagaacggc taatcaacat cggattagtt gaagcaccag ctccattacc
    18001 atgaaggata tctgtcaaaa gtttacgcac tttctgagcg taaacttgga agttgcgagc
    18061 agcttcttca gagcgaccta acttagcagc cgataccatt tgcatggcat tagtgatttg
    18121 actcgtattt tttgttgagg cgatttttgt tttaatatca tttagagaca ctgccatctg
    18181 acacctctat tcttattgga agctagattg attgagaaac tctgtaatcg cagcatccaa
    18241 gactgcttct tctggcaagt cttttgtatc acgaatggtt tccaaaatct ctggatgttg
    18301 agcatcaaag aaggcatgga actcttcctc gaaacgaaca atatcatcta ctggaacagt
    18361 atccaagaaa ccatgtgtca aagcataaag aatggttact tgtttctcaa caggtaatgg
    18421 tttgtgaaca ggttgtttca agacctcaac ggtacgacgt ccacggttca acttagcctg
    18481 tgttgctgcg tccaagtcag aaccaaactt agtaaaggct tccaactcac ggtatgaagc
    18541 aaggtcgata cgaagtgtac cagcaacctt cttcatggct ttgatttgtg cagaaccacc
    18601 tacacgagat acagatgaac ccgcatcgat ggctggacga atacctgcat tgaagaggcc
    18661 atcgccaagg aagatttgtc catcagtgat agaaatcacg ttggttgcga tataggctga
    18721 gatatctcct gcttgtgtct cgataaatgg tagggctgta attgatccac caccaagttc
    18781 atcagaaact ttagctgagc gctcaagcaa acggctgtgg agatagaaaa catcccctgg
    18841 gaaggcttca cgacctggag gacgacgaag caagagcgat agttcacgat aagctaccgc
    18901 ttgttttgat agatcatcgt atacaatcaa aacatgctta ccttgataca taaattcttc
    18961 cgccatagca accccagtat aaggagctag gaagagcaat ggagatggtt gtgaagcaga
    19021 ggctgtcaca acgattgtgt agtccaaggc accgtactga cgaagtgttt ctacttgcgt
    19081 acgaactgtt gattcttttt gtccaatcgc gacgtagata cagatcatat cttgatcttt
    19141 ttggttcaag attgtatcaa tcgcaatggt tgttttccct gtctgacggt caccgataat
    19201 caactcacgt tgaccacgac caatcggtac aagggcgtca atagctttca aaccagtttg
    19261 caatggttct gaaacagact tacgttgcat aacaccagga gctggtgctt ctactggacg
    19321 agttttatca gtgtggattt ctccaagacc gtcaactgga cgaccaagcg gatccacaac
    19381 acgaccaatc agactttcac ctacagggac ttccatgatt ttccctgtac ggcggattgt
    19441 atcgccttca cggatatctg taaagtcacc taggatgata ataccaacgt ctgttgactc
    19501 caagttttga gccataccat aagagccgtt ttcaaaattc aacaactctc cactcatgac
    19561 attttcaagg ccatgagcac gcgcgatacc gtccccgata taggttacaa cacctgtttc
    19621 agtcacatca aaattgggtt tgaaattttc aatttgttgc ttaattaaag cgctgatttc
    19681 ttgtgcgtta attgccaaaa gaacaccact ttctatttca aattttcttt aacaacttta
    19741 agttgttgtt taatactcac atcaattgtc ttgtgattgg caaaaatgac aaaaccacca
    19801 atgagacttt catcgatttg ttcttttaca ctccttactt tcagagacat ttttttctca
    19861 atcaaaggga gcaaacgagt cttctgttca tcagttagag gatgagcaga cgtaatcgtc
    19921 acttcaaatc gatttgtttc tttttcaagt cggttcaagc aatctacaag cacatcataa
    19981 aaaagatttg ctctgtgatt gtaggccaga acctggataa agttttgtaa taaaggcgac
    20041 acagaatctt ggaaaaaagc aattgttttt tccttatccg actcgtctac tgccacttgt
    20101 tttaaaaaag aaggcagacc tgttttttca acaacttgct tgatttgagt caagtctgaa
    20161 aagatacggt cttcttctcc tttttcaagt accaattgga caaaaggcat gctgtatttt
    20221 tcaattacct ttactgtttt cttgtccatt aagcttctcc tagctgatcg atatactgat
    20281 caatgagtgc tttatgggca tgactgtcaa ggttttgtga gatgatttta ccagctaagc
    20341 tgatggtcaa atctgcgacc tcacccttaa cactctgtaa agcttctact ttattttgag
    20401 caatttcttg attggctttt tcttttaagt gtcctgcttc tagtttagca tctgctaaga
    20461 tattagcctt actttgctca gctgtttcct ttgcattttc aatgattgtc ttagcttctt
    20521 tacggctacc agccaattca tcttcgcgtt tttgagccaa tacttctgct ttttgacggg
    20581 cttcttcagc tctatcaata tctgaagcaa ttttttcagc tctttcttcg aaaatgcctg
    20641 taatattaga ccatgcaaat tttttaatca agactagcaa aagaataaaa gagccagtga
    20701 ttaaaataaa attaccaatt aattcaccta ctgttacgtg catcagttac tcctttctat
    20761 tcctcttcaa tattaatctt attccctaaa tacacagatg tcaaaagagt aaaaacataa
    20821 gcttggatgc aggaaataaa gacagaaaat gcagtccaag ccaaattagc tccaaaggct
    20881 actggatacc aataaatagc ttggtgggaa agaagaagta acaaactcgt catgacctct
    20941 cctgcaaaga tattcccaaa aatccgcaaa gccaaagata agaagtttgt aaattcttcc
    21001 aagatattca tcggtatgac aaaaacagga ctcataaaag attttatact ttttttaaat
    21061 ccacgacgac gaacgctttc tatatgtgtc aacaaaatga caagaaaaga taaggttaag
    21121 tcatactgta aattagcggt tggcgaactc caccagttag tcccatcgat cgtttgaagc
    21181 tttgtcatta agccaaggtt attggcaatc accatgaaaa ggaataaaca aaggaaaaag
    21241 agtgagtaat ctttcatgta gcgcgaacca atgttaggtt ctgtaaatcc aataacaaag
    21301 tcatagacat actcaagtat attttgcttt cctttgggtt tcaaggtcat attgcggctt
    21361 gcccaataaa taaagacaaa aataactccc acaatcaaca aagtcatggc taacatagtc
    21421 agattgaaga taacaggacc aatagagatg attggattaa tactttcttc catctaaaat
    21481 cctccctttt cttctcgttc catgtattta tttgataata aatgagaaga caagagttac
    21541 aaagaaagtt ccttcaataa aggcaacacc taaaaacatc aaactacgaa actcagaaag
    21601 catatctggt tggcgtgcta ctgatttaaa cagtccattc atcaataaac cttcaccgac
    21661 agatacgccc atacaggcaa tacataagcc taaaaatgtt aaattcataa caaattctcc
    21721 tttaaaataa aatttactta cttagtgtag tcctaaaatt taaatttgtc aacttttaac
    21781 cgctattgga agcgtttaat aaaaattatt tccattttgc taaatttcaa gttcaagtta
    21841 gccatccaga agtcttctct gggtgacttg tagtccaagc attttttagg atagttgtta
    21901 atccactttt cgatgaatgc gacttctttg ggagtcattt tcttggttcc cttaggtaac
    21961 tatctacgaa tgagcctgtt gtgattctca ttagttcccc tttcccaaga ggcatagggg
    22021 tgcgcataat agatgtgctc ctcagaaaat atatcaaaca agcgattgaa ttccgttcca
    22081 ttatctgccg tgatggaaag aatcttgtgt tgttttaaga tgagttttag agcctgattg
    22141 accacctcag cacttttatt tggaatcaat cggatgatct gatgtctact ctttcgatcc
    22201 gtcaagacaa gcaagcagta gtttttcgct ctcgtaagta gaaccgtatc aatctcataa
    22261 tgcccattct ccaagcgaag attgatagct tcaggccgct gtgcgatgga ttgaccagca
    22321 ggtttaaagt tgatgctagc ctgtttctta agcgcttttc cttttctagg gtaaagcaga
    22381 tcctgtttgc ttaaccccaa ttttccatga tgaatccaat agtaaatggt tgaaattccc
    22441 acgttaaccc ctttagccat caccatcatt tcaggcgaaa atttttggtt atgatagtgg
    22501 agaatctttt cctttagttc cttggtcacg cttaatttcc tgaccgagcg cttgcgattg
    22561 ttttcataag actgttgagc atagtcggca gaataaacct ctttgaagcg cccttttcca
    22621 agacattgtc ggactgtccc acgcttgatt tcagtgtgga tagtttgagg aacttttcca
    22681 agcagagagg caatttctct atttgatttt ccttcttttt tccatcgttc gattaagcga
    22741 cggctatcga ttgtcaaatg tttacctttt gtagtataat ggttttgcat ctctgtgcct
    22801 ttcttgtgtt tgtggttgaa caacaagtat aacacagagg tgttttctta tgcctacaag
    22861 agctttcatt atttccattt tcttttggat ttcactctat tctgaaaaac ttgtgtatat
    22921 ttactgaagc tagcaaggct tacctgtaaa tttaatgaaa gcaacacaaa atccgagagg
    22981 ggaatctcgg attaatgtca atttaaaaag atagagagtt tttagtttaa ataaattgtt
    23041 ttaaaatatc aacaacatca cttcttttct taacctgata agccttgatt cctaattttg
    23101 gggctacgat tatattgtcc tcaatatcgt ctagaaagac acaatttcta ggttataact
    23161 ggtatttatc gatagttact catatacatc agtccacctc catactcgcc ttacagattc
    23221 ttttggtaat aatatctttg cctaatgtag agatagtctt gcaaagaaaa aacttccttg
    23281 tagccatgtt tctgataaaa gtccagtgcc tggaactggt aagtattgac aaaggcaaaa
    23341 caacaatttc gattcttagc ttcactttct gcctgttgca atagttttga accgattcct
    23401 tgccctcgca gttcctcttt tacaaacaaa tactcgattt ctagccaatt tccaaaagtc
    23461 tctgctatca aacccgcaag gagattgccc ttttcatctt cgacataaag attaagtggc
    23521 tcactttcag cctcttctct ttttgaacgg ttataaacac gaatcagatt ccctatttct
    23581 tgcgatttat gtgattcctt attttccaat ctaaggtata atgaaatgaa ataaaacatg
    23641 cgcaaatcga ttaaggaatt taatctaatt tctaacaatg tcttagaaat caaagtgtac
    23701 tattttaact tcaatgcatt atacatctaa tactcaatga aaatcaaaga gcaaactagg
    23761 aaactgacga agtcagtaac catacatacg gcaaggcgac gctgacgtgg tttgaagaga
    23821 ttttcgaaga gtagcaaaat ggaaaaagga gtgagtgaag cacatcgcct ccccactcct
    23881 ttttctgttt ttaggctgtt ttttcaacct tcaagatttt tacatcatag ctaccaacag
    23941 gcgtttcaat ggttgctgta tcacctgttt tcttgccaat caaggcctgc ccaattgggc
    24001 tttcatttga aaccttacct gcaaaggcat ccgcaccagc tgaacctacg ataatataaa
    24061 cttcttcttc gtcctcacca atttcttgga tggtgactgt tttaccaatc gctacttcgt
    24121 cctgggcaac tgcgtcgcta ttgacgattt cagcatagcg gatttttgtt tctaagctag
    24181 agatttgtcc ttcgacaaag gcttgttcat ccttagctgc ttcgtactca ctgttttctg
    24241 aaaggtcacc gtatgaacgg gcaatcttaa tgcgttctac cacttctggt cgacgaacca
    24301 atttcaattc ttctaattct ttttcaagtt tttccttttc ctcaagggtc ataggatatg
    24361 ttttttctgc catttttctc aactttcttc tgataatatt ttctaaagaa aattatgtga
    24421 agtatcacat aattttagtt tgtttagttt aatttgctgt tgacatgttc agcgacattg
    24481 cggtcgtggt cttcttgatt gttagcatag tagaccttgc cttctgtgac atctgctaca
    24541 aagtagaggt tatcgctctt agtttgattg atgcttgact caatcgcatc cagacttgga
    24601 ctatcgactg gaccaggcat gagacctaca tttttataaa cattataagg tgaatcaatg
    24661 ttggtatcaa tcgcaacatc ctcagctaga ctgatatttt gccccagttt tccttgggca
    24721 tacaagattg caatattact ttgaagtggc atatcacgat tcaaacgatt gtagaataca
    24781 cctgcaatga gcttacgatc ttctgtcttg gcaccttctt tttcgaccaa ggaagcaatg
    24841 gtcaacaact cattgacagt caaattttta gatttgatag tactatagta aggagatagg
    24901 ttcttatcca tagcagctaa catctcatca atcaagctct caatagttgt gctttccttg
    24961 atagagtatg tagctgggaa aaggtatcct tccaaacgat aacgcgcacc gctgtctttt
    25021 acaggcaaac tttccagtaa agtaggatat ttcgctactg cttgactgat aaacgtctca
    25081 tcttgaactt tagccaagaa agcctccgct gtcaaagact ctttgaagtc accttgcaat
    25141 tgacccacag cttgagcaat ctgatccaag gtataacctt ctggaattgt caaagtcgca
    25201 agtacaggtt cttgcggttc atctgttcca cctttttgca actctttgag taagtcttct
    25261 gtactcatac tcttttgcaa attgtagtaa cctgctttca agtcggtata atttttatac
    25321 ttggcataaa aactaaaaat cagaccatgc tttaccaaac cagctttttc aagcgtcgta
    25381 ccgatttctt gaacgtttga accttctgga attccaaccg tcacatattt cttagaatta
    25441 gcatcgatag gtaacaaaga atctagcacg tactggtaac caaagtaacc acctgctgag
    25501 agcaaggcaa ggaatacaag gaatgaaatc acaaaagctt tcacatgtga cttcttctct
    25561 ttcttaggct taacgggttt tgctccttct ctacggctac gacgtgatgt atcgctgatg
    25621 atatccactg tttctgtagc aggcgtaggt gtttctgaac ctgcttgttc tgcttttttc
    25681 tctgccgtcg tataggaaac agctaccctt gttggggttt cattgtattc tctttcaagt
    25741 ttcttaggtc taacaggacc tggacctggt cttgatccac tttcttccgc tggagaagaa
    25801 ggtacatctt gacttggatg acttggaaca ccaggagttt ctctttgaat ctcatctgct
    25861 ggagaagctg gtacaccttg acttgggtga gtaggcacgg taggagcttt tctcataatc
    25921 tcctctaccg ttgacaagga atcagccatg agttcttcag ctgaaggttc atttgcagga
    25981 gtgcgaacta ctgcctcatc ttctttcaga acttcatcat agccttttac tttttctaaa
    26041 tctctcagaa tctgctcttt aaagcttaat ttctcttctt ctcttgactt ttcactcaaa
    26101 agtttttcct ccttgttgat aatccataat attatatctt aaaagtccaa aaaaagcaat
    26161 ctatgatact tttcctaact tattttttca tttcccagac catatcatac catgtttccc
    26221 ctgcaaaggt tgactgggac tggccttcgt tgacaaatcc atgtttttca taataggcga
    26281 tgagatagtc atgacaggtt agattaatgc catctctctc atcttcaaga gcaacttctt
    26341 tcaaggctgt cagcaatttc tgacccagtc cgagtccctg tgcctccttg gcaatagaca
    26401 gacaggtcac agagatataa ccaccaggct catgactata gtcttttatt tcttctgtaa
    26461 aagactggtc ttgcagatgg cggtgcaggc caactggtcc ttcgatataa cccatgattc
    26521 ttccttcttt ttcagcaacc agaaaagagg tctgaatttc tctcaaatgt gcttcaaaga
    26581 cagaaggagg aatggcttct tcgaccgaaa aattttcaaa ttcaagttca acaatccgat
    26641 ccaaatcttc taatcttgct tgtctgattt tcattgttcc tccagataaa agggattaaa
    26701 ccaaatcata ctatagccct ggctagttgc atagagcaaa gttgcttctt catcaacaaa
    26761 accgttcatt tcaaaatagg aaagcagctc atcaggactc tccaaacgaa tccctttgta
    26821 atccagctca actgccacct ctttcaaggc tgcaagaaga agtgttccca agccctgtct
    26881 ctgatggtca gactcgatga ctaaagaatg tacttttaga tattgcggat tgtctgactg
    26941 gggacttgat aaaatatagc ctaaaagttg attttcatcc ctagctagaa gaaaggtatc
    27001 cgcacactta cggatacttt cttctaaaat atgggaaagt tgctgctttt cagctggaaa
    27061 agacgaggtc tgaagtgccc ctatctcagg caaatcagac ttgcttgcct gaatgatctt
    27121 aattggaatt tccatgggaa catcctattg aacattgctt gtcaagttag acaagagacg
    27181 ctcaaatgag tattcatagg tttggatgtc tcctgctccc ataaagacgt aaacagcatt
    27241 gtcatggtct aggagcggag aaacattttc aacagtaatc acttggtgtt ttttgttgat
    27301 tttgttggct agatcttcta ccttaacgtc accatgatct acttcacgag ccgagccata
    27361 aatttgcgct agataaacag catctgcttg gtttaaagca tgggcaaagt cgtccaacaa
    27421 ggcaatggtt cttgtaaagg tatgcggttg aaagactgct acaatttcct tgcttgggta
    27481 tttctgacga gccgcatcca aggtcgcaat aatttctgtt ggatggtggg caaagtcatc
    27541 gataatcact gtatcattga caattttctc agtgaaacga cgtttaacac cagcaaatgt
    27601 tttcaagtgc tcacgcacca agttcaaatc aaatcctgct gtgtaaagaa gaccaataac
    27661 ggctgtcgca ttcatgatat tgtgacgacc aaaggttgga atgtggaatt gccccaagtt
    27721 ttgtccacgg aaatgaacgg tgaaggttga accagttatt gaacgaagaa gatcactagc
    27781 tacaaagtca ttgccttcaa cttcaaaacc ataataataa attggtgcat cagacgtaat
    27841 cttacgcaat tcagcatctt caccatagac aaaaagaccc ttggtgattt gtttggcata
    27901 gtcgttaaag gcattaaaaa catcctcgag acttgtgaaa taatctggat ggtcaaagtc
    27961 aatgttggtg ataatagagt attctgggtg gtaaggcatg aagtgacgct catattcgtc
    28021 agattcaaag acaaaatatt tggcattggc cgaaccacga cctgtcccat ctccaatcaa
    28081 gaagctggta tctgtaatgt gagacaagac atgagacaac atacctgtcg ttgaagtttt
    28141 tccatgtgct cctgctactc ccatgctaac aaagtcacgc ataaagctac ctagaaactc
    28201 atggtaacgt ttgtagctga taccattttg gtccgcatag gcaatttcga cgttgttatc
    28261 tggacgaaag gcatttccag cgataatttc catatcaccg tctagattct tttcatcaaa
    28321 aggaagaatg gtaattcctg cctgctcaag accgcgttgg gtaaagtagt acttttcaac
    28381 atctgatccc tgaaccttgt gccccatctg gtgcaacatc aaggccaagg cactcatccc
    28441 tgatccctta attccgataa aatgatatgt ctttgacatg ttttctcccc tattctgtca
    28501 ttctggtcag attcaactct tgggcaaccc gacgttcttg ttctgtttgt ttactttttt
    28561 tattgtagat ttggctcttc tttagaaaat cataattgtt tttctttgga gcaggtgctg
    28621 acacttcttc attcttggta gggatagaat gaacttcttc cgccaagata taatgagact
    28681 gggtcaattt ttggctatat ttgacaaatt caccaggatt ttccttttgg aaaggagttg
    28741 tcggttgatt gccctgtcta actagactgg gctgagaatg acgtctcgca aggctgaaat
    28801 cctgagttag atagttagca gagcgtttct ttttcaagtc tgcacgcgct tcttcacgcg
    28861 ccacctccgc atagctcttt ccttcttttt taacccctaa aggagctttt ttaggtttcc
    28921 ctacttgctt ttcaatcggt tgtactggtt tttcttcagc aataggagcc cattctaaat
    28981 aatttttatc tcgatactca cccttgatat tactgatcag atcagactca tcatagagat
    29041 tcatgactgg catttcagtc aacatgacct cgtcatctga caccaatgga aatcgttctt
    29101 gtttcatttt ctatttcctt tcaacacttc attatagcgt attgtcttga tttttcaagt
    29161 gctggcttca gaaattccca aaatttctct aatttctgct agggtcagac taccacgtga
    29221 ctctgtgccg tccaatactt gtgacaccag atgtttcttt tgttcttgga gttcctgaat
    29281 tttttcttca atggttccct tggtcaccaa gcgatagacc tcaaccgttt cttcctgacc
    29341 catccgatgg gcacggccaa tggcttgcgc ttccaccgca ggattccacc aaaggtcaac
    29401 caagatcact gtatctgcac ctgtcaggtt cagaccgacc ccaccagcct tgagggaaat
    29461 cagaaaggca tctctttctc cttgattaaa ggccttggtc atgtcttgtc tttccttggc
    29521 tggggttgaa cccgtaattt taaaggaagt caggcccaag tctggcagtt cttgttcaat
    29581 tttttccaac attcccttga actgagagaa aatcaagaca cggtgtccgc cgtctgccac
    29641 ctgtaccagt aggtctcgga gactatctag tttgccgctg gctccctgat aatcttccat
    29701 aaacagggca ggagtgtcac atatttgacg caagcgcatc aaaccagata aaatttccac
    29761 acgacttcgc tgaaattcct gttctgacac ttgagccaga tggtctcgca tctgttgtaa
    29821 ctgggcaagg taaatagcct tttgctggtc ttccagttca tttttataaa ccacctcaat
    29881 caagtctggc aattcagtca gaacttcttc tttcttgcgt cgcatcacga aaggcttgat
    29941 aaactgagcc actcgctctg ctggcaattt cataaattct ttcttgcttg gcaaaagtcc
    30001 gggcatgacg atttggaaaa tagaccacaa ctcacccaga tggttttcaa tcggagttcc
    30061 tgacaaggca aagaccgacg gcaccacaaa ttgtctcaag gtctgggcaa tcttggtctg
    30121 ggcatttttc atgacctgag cctcatctaa gaaaaggaag tcaaaggcca tcccctgata
    30181 aaactcactg tcctgacgga aggtggcata gctagtcaca tagatttgat ggctctcggc
    30241 aagaatctcc tcacgacttg ctttcaaacc atgaacaaca accacatcca actgtggggc
    30301 aaatttctga aactcatctg cccagttgta aatcaaacct gacggagcga gaatcaagac
    30361 tcgactttct tttgtcactt gactagtcaa aaaagcaatg gtctgaaggg ttttcccaag
    30421 tcccatatca tcagccaaaa tcccaccaaa accataatga tggagcatct gcaaccagcc
    30481 aattcccttt tcctgataat ctcgcaagtc agccttgacc tgagttgctt gcaaaggaaa
    30541 gtcctctgga tgcgtcaaat cctgggccag attctggaat tcttgtgaaa aagaaacacg
    30601 gtctcgccct tcaaagagat gagctaaact gtaggccaag gatttccgag cctgcaaggt
    30661 tccatctttt aattcaaatt gccccagttc ctggagattt tggcgaattt tcttggtttc
    30721 ttcatcgaaa aagtaaactt gattagacga atcaatataa aaatcctgat tggcaaccaa
    30781 ggcctgcatg gcttggtcga tttcctcctg ggcaatattt tgaaaatcaa actggatttc
    30841 caagagacct cccttggagg caatctgcac ctgaggactc gctaggctat aaagctcttc
    30901 tagtttatct gataggtcaa catgcccgag tttttcaaag actggaatga tatcatgaaa
    30961 aaaatgatag acagactccg cttttaaggc ctgacgccaa gattgaaaat cggcttcaaa
    31021 gcccgcagcc aaacagactt ggaaaattct ttcttctaag tccgcgtcac ttgaaaaggg
    31081 taattcttct agctcttgtc ggctagatac ctgtctattt ccataatcaa actgaatttc
    31141 taaacgaatc cgattatctt cttccctgtc aaagtaaaaa gagggcgcaa aagttttgat
    31201 ttgtagacgt tctggagctg aaacggtgcc catctggata aaaagagtca gacaggaggc
    31261 caatttgtct cgatcactgc tatcaaattg caggtatttc tttccttgtt gacccacagg
    31321 taacgcttta atttccttga gaagacgcat ctgctggtct gttaaaaaat aaacctgacc
    31381 tttatggaaa agtactgctc cttgataaaa gacattgacc ctaggactct cactgatttc
    31441 catttcaaaa tagtccgagt attctgttac tgtaaaggca aatagattgg catcagcatg
    31501 catatcctga aaaagcaggg tttggtagct atccacttga tggtcaaatt gaaaatgggg
    31561 caaggccatc agtaaattca caccctgctc aaaaaaggtc agagggaaaa agaggtgccg
    31621 accttggttt tggaaaaaga ggtctggaac cagcccttcc tccgttagtc cgtgcaagaa
    31681 agtcaaaagt tcttggctgg catcatcaaa ggcttcccaa gaaagagact cctcataaat
    31741 cttgccaatc atatacgact ttctctgctc gacaatcctt aaaaaaagtg gaatatcccg
    31801 aatgacatag tatttttggc tattgatttg gccgattctc agagtccaca agatatgatt
    31861 ggttcctgct tccacctgac ccacagctga taactcatag gcgcattctg attttggaga
    31921 taaaattcga ttcaaaaact tgccacccaa ggtcaccttg gtttcaacgg cctctttttc
    31981 ttcatgacct tcttccagac tccacaagat ttcctgacca cgctcatcat ttttcagaaa
    32041 atgctctagc gctgccaaat gcacacagta gcccctcttt tgaaaagaat cacaggcaca
    32101 aaaaaccaaa tcatcctcta aactatagcg cagttcttct tctgcaacgc gagcgtagag
    32161 ccgattgttc ttttccttga tgatatcaac cttaccagtt tcataaaggg caacaccttc
    32221 gatacgaact ttccccggaa tcaatttagc catattttca cctttacctt atctttttat
    32281 tataccatat tttcgcctat gaaaatagcc ttctaggaag acttttctcc tagaagactg
    32341 gatttttaac gtttggcaaa agtaaccaca atccgctgac agacttcctg caacagagat
    32401 ttgggcatag ctatattgat gcgggcatgg agacttcctt cctctccaaa atccaaacca
    32461 cggttgagga taaccttggc ttcatttctc aacaactctt gcaatgtttc atcagtcagg
    32521 tcataggctg aaaagtcaag ccaaatcaag taggtacctt gcggtttcat gaccttgatt
    32581 ttagtctctt ttccaaatag atctaccaca taattgatgt ggtcttcaaa gacttgcttg
    32641 agttcctcta gccaatcttt accgtatcga taggcagctt ctgtcgccaa ataacccaag
    32701 cctgaaattt catgctgatt attggccaac aggcgtttct ggaaagccag tctcaactta
    32761 ggattttcaa tgactgcata ggaatttttt gttccagcaa tattaaatgt tttagtggca
    32821 ctgctcaaga cgatagcaaa atttttgaag gcaggattga tggtattgaa agactggtgt
    32881 ttgtgaccaa agagggtcaa atcttggtga atctcatccg aaactaacaa aacaccgtgt
    32941 ttttggcaga gttggccaat cttctccaac acttcttttt cccaaacacg tccaccagga
    33001 ttgtgaggat tgcaaagaat atagagttta acctcctctt ccaccaaatc cttttcaagt
    33061 tggtcaaagt caatctcaaa cagaccatcc ttttccacta aggaattagt aatcaatcta
    33121 cgattattca acttgacact gcgagcaaag ggtgggtaga caggcgtgtt aattaaaacc
    33181 gcctcgcctt cttttgtaaa ggtttgaata gctgttgaga tggctggtac cacaccctcg
    33241 ataaagacaa gagcctcttt gtcaaagttg taaccgtatt gtgtagcttc ccacttttga
    33301 acttccttaa ttaagtcttc actggcatag gtataaccat aaaccagttg gtctgcgtaa
    33361 gtttgcacgg cttggcggat ttcaggcaag accacaaagt ccatatccgc tatccaagct
    33421 ggtagaactt cactatccgt ttctgtttct ttccatttat aggtatggtg ccctaaacgg
    33481 ttgggcaggc ttgtaaaatc atattttccc atctttgtct tatccttcta aggcttggcg
    33541 caaatctgca atcaaatctc tagtatcctc aatcccaata gacaaacgca agaggtcatc
    33601 tgtcaaacca taagaatggc gtacttctgc tggaatatca gcatgagttt gagtcgttgg
    33661 ataagtaata agactttcca ctccgcccaa actttccgca aaagagaaga ccttgagact
    33721 gttcaaaata tgaggaatgc gtgtttcatc ggctacttta aaggaaatca tgcctccacg
    33781 accagtgtag agaacttcct taactgctgg agaatccttc aaaaaggcaa ccacttcttg
    33841 ggcgttagct gttgagcgct ccatacgaag agacaaggtc ttgagaccac gaagcaactg
    33901 gtagctgtca aatggagaca agactgcccc tgttgtattg agattgtaaa aaagcttctc
    33961 gtatagttct aaactattgg tcacaaccac tccagccaag acatcattgt ggcctgctag
    34021 atacttggtt gctgaatgga gaacgatatc tgctccatct tcaatcggac gttggtagat
    34081 agggctatag aaggtattgt ccaccaccac tttggcaccc ttagcatgag ccaattttgc
    34141 tagtttttcg atatcaaatt ccaacatcaa gggattggtt ggggtttcga tatagagaac
    34201 atccacatcc ttttctaact cagcaatcaa ctcttcttct gtattggcat aggtaaaatg
    34261 gaaacgacct tcctgctcca cttggttaaa ccagcgaaaa gaaccaccgt aaagatcacg
    34321 cactgccaag accttacttc ctactggaaa gccgctaaag gccagtacaa tagctgacat
    34381 ccctgagcta gtcgctaggg catagtctgc tgactcaata gccgccaaga cttcctcagc
    34441 cttactacga gttggatttt tagtgcgcgt atagtcaaac ccagtagatc gaccaaactc
    34501 tggatgctga taggtcgttg aaaaatgaag cggtgtcacc aatgcacctg tcgcttcatc
    34561 tgacttaata cccgcctgag ccaaaattgt gttaatgtgt aattccttgc tcatacaata
    34621 cctccaaatc tatagtaact attgtaccac ttattttcat caactcattt tcttcttttc
    34681 aagagctagt tatagtttca aactatataa aaagggagtt tttcctgctc cctttaatag
    34741 actataaaat ggtgaatctc aaaagacacc ttcactctat catttgctcc tgcacaaaac
    34801 gagcataacg ctcatgattt tccagtagtt ccttatgagt tcctgagcca gtgattttcc
    34861 ccccctctaa gaagaaaata caatccacat cttttaccgt tgacaaacga tgcgctataa
    34921 tcacaaccgt cttctccttt aatgcagaat agaggatact gataatcgca tactcagaat
    34981 ccgcatcaag attagcagtg gattcatcaa atataagaat ttcagcatct tttaagtagg
    35041 ttctagctat ttgaagtctt tggctttgcc cccctgacaa gaatcgtccg cgttcaccaa
    35101 cttcagtatc tagtccctct ttcatggagc gaatctcatc acctagtgat actaagtcta
    35161 gcactttcat caattcatca tcagttacta agcgattcaa accgagacaa agattgtcac
    35221 gaatactgcc agataagact gcattatttt gtgaaaccca agcgatttta cttctccatt
    35281 cttttaagtt aaaatcatat atacttgatt gctccattag aatatatcct gaaagcggtt
    35341 tataaaaccg ctctaacaaa cgcacaatcg ttgattttcc tgatccagat ggtccaacaa
    35401 aagcaatttt ttgccccttg aaaattgaac aagtaatatc ctttaagaca ggtcgatttt
    35461 catcataacc aaaatagaca tggttaaaat tcaacccttg tcctgatacc gattttcctc
    35521 actcaaattt ttctttagga actgcaagca agttctccag tgcaactgaa gatcccttgc
    35581 tcctagaata aatagttaca aaattagcta tattactaat aggattaagt aattgaaaga
    35641 ggtaaatcaa aaacgaaacc aaggttccca cagatatata tcctgcgctg acccgataac
    35701 ccccataggt tagcatcaca actatagtcg caaagataaa taagagagca aacggggtct
    35761 caaaagaagt aaccctatct gatttcagtg aattgttttg taccctttca atacaattat
    35821 ccaaaacatc ctgtacactt ttctctgctt ggttagtctt aattaattca tgttcttgaa
    35881 tcttttcagt caattgccct gttaaaaatc cgatttcctc ctgtaaacga cgactatact
    35941 tttcactgat attggaaagg ggcaagataa taaacatcat acaaggaaga gtgatgaata
    36001 aaagtagaga aagattccaa tcaagactaa ataagactac aatggaacca agtaccataa
    36061 ctaaactcag aataatattt gggaaagtcg taattaaaaa ctcacgaatg acactcgtgt
    36121 cattgacaat ggcagaagtc aactccccac tttggctctt atcaaagaag gatttctctg
    36181 cataaatcaa cccctctatc acttttttcc tgatttttgc tatctttttt tcacccgatt
    36241 gactaaacag atagtaacca atagaagaaa acaaggcttg accaataaaa atcaaaaacg
    36301 attgaaatac tttggaacct atattttcaa tagaactccc atctattaaa ccctttaaga
    36361 taaggggaag caacaaagca agtagactag acagaacaag taagaaactc cccataatca
    36421 ccttagtatc tactcttaat aattttaatt tcataaatac tccttataat atttcaacgg
    36481 ataaagtcga gaataactca atttgaggat aaaatctaat aaatcttcct ataacaaaac
    36541 gcataacatc taggatttta tatacctgat attatgcgtt tttaagcaca aagacttctt
    36601 acacaaactt atctacaatt agattttatt tgacatgttt tgccaattct tcttgggctt
    36661 ttttattgga ttcttctttt tctttcaacc atttttctct ggcttttgca tattcgtctg
    36721 ttgtgacaat cttatcttgt actttgaggt atttatatga ttcaacccct tttgtaccgg
    36781 ttaaaccata ggcagcagca aatggtacgg ttcttctcaa tgatggtgtt cccccacgcg
    36841 aaacacttgg aagaactaaa gaactatcaa tcaaccaagc ttgaatatca gcatatttct
    36901 cataacgttt ggctggatct tgctctttat tagcttcttc caacatttga gtatagacat
    36961 ccagtccaac tgccttagcc ttgtcattgg cttctccagg ctctagtcca agattttgta
    37021 gaactcctcc actattagta ttaaaaatat cgagataggt tgacgggtct tgataatcag
    37081 gtccccaacc gccatgatat aaatcatagt ctttctgagc agctgtttga gcaaagtagc
    37141 ctgaactgtc aaactcatct gatgttaatt gctgaatgtc aatcactaca ttatcagaac
    37201 ctaaaacaga ttcaattgat tgtttgatag aactaactcc ttgtatgcct actttatctg
    37261 ttacttccac agtcttatcc aagtggattg ggaattgaac accctttgct tcgagttctt
    37321 tcttagcttc cgcaaactta gccttggctt tctcaggatt gtagtaaggg tcttgaccat
    37381 ccgcaaagtt gataccttgc cattccttac catagttgac catcttagag gctacaactt
    37441 caccaaagtc ttttcccttg atactgacaa agtttggagg aaccactagg ttacgcaaaa
    37501 tctttgttgc accttctttc ccttcagact gagccccata agatgttctg tcaaaagcaa
    37561 aattgatagc ctgacggaag tttttattga gaactgcttc ctgagtcgat ttcttttcaa
    37621 tgtcacttgt tttagaagta taattgtaag acttcctatc taggttaaaa ttaaagaaat
    37681 atgaagttga attttgcata ctatagatga tattgttttt gtatttttct ttaatccctt
    37741 catagctgga gctgttagga aaaagacgag ccgtagtata agcaccagct gtaaaattac
    37801 gttccagtga ttcttggtcg ctaccatcat agtaggtcaa tttcacatcg tctacaaaga
    37861 cattcttagc atcccagtaa ttagggtttt tcttatattc aatagcagat tttgagacaa
    37921 gtgctttcat caagaaaggt ccattgtaca aaatactaga tggatccgcc ttcccaaaat
    37981 catccccttt tgatttcagg aaatctgcat taacaggaaa aagtatcgtt gcaagtgttt
    38041 ttgaattcca gtaaagttct ggtttaacca aagtatattg aaccgtttgg tcatcaagtg
    38101 ccttgacacc gacagttgaa aagtcgcttg ttttaccagt gatatagtca tccaaaccag
    38161 caacagagtc ctgcactaga tacaaggctt ctgatttttt atcagctgca tattgcaaac
    38221 ctgtcacaaa atcctgggca gttacaggcg catattcttc tccctcagaa gtaaaccact
    38281 tggcatcctt acgaagtttg taggtatagg tcaaaccgtc ctgagaaaca gtccaatcct
    38341 ctgctaatga tggaataata ttcccatatt ggtcattttc taataacccg tctaccaaat
    38401 ttgcaacaat atcggatgtt gctgcgcggt tttctgctag atagttcaag ctagatggat
    38461 cacttgaata aacatagttg taggtttttg acgccgtgct agaatttcca cacgcgctca
    38521 ataaaactcc tgtacccagg acaagacctg ccaaggttag atatttgctc ttagactttt
    38581 tcatttccgg aacctcctgc tttaaatatt tgttttatta tacaactctt ggtttgttta
    38641 gtcaattgtt ttttccaaaa aatcaaaaaa acctcatttt ctatttttga aagataattt
    38701 tagctatttt tacgctaaaa aaggaataag tttcaagttc tcctaaaaga ttgttcaact
    38761 tattcctttt atttataaat gctaccttac gaaagcttaa attttgctcg caggcgatct
    38821 gcttgggctt ttcctattac cttatctaat aaataggtac gcagactcat aaccatataa
    38881 agtccacccc ccatggcacc gacaagagct acataaaaga agctccacaa acgtccactt
    38941 ggttggaaga aaaatcctaa cagccactgg atggttccta ttaacagaaa catgactagg
    39001 gtcagcaaac tgattaaaat agttcgcttc aaaatcacct tgcgcttgac accagttact
    39061 ttacaaatat cccgatacat caagacgtta ggaatgatga gagcaatggt tgttgaaatc
    39121 aaaggaccat aactgtggaa gagggcgatg gtaggtagtt gcaagactag cttggcaata
    39181 gaaccataga taaaatagag aacggccttg cggttgcgga acatggcctg aagcattgga
    39241 gacaagacca tgtacaagcc taaaataata gactgcaaaa ctgcaaagac aaataagccc
    39301 agagccaaac tatctggctt accatagaag actgtatata gaggttctcc taccataacc
    39361 actccaaccg ttgctggtag caagaacata aagagtaggg tgagactgtc ctgaacgaga
    39421 cgagaagctg ctttcaagtc ccccttgaca tagttttccg tcaaaagtgg caaaccaaca
    39481 ctcccaatcg aaacccctac agaaatcaaa atcatcgtga ttttattagg attggctgag
    39541 aaataagaaa acatgacaac caagtcctca ttgctgtagt tggtaaacca gctcatacta
    39601 ttgataaagg tcagctgatc caaaatctgg aagagctgga tggcagaccc tgtcaggata
    39661 aaaggaatgg cttccttaat ggtatcaacc aagagacgct tactgttaat cttatctcct
    39721 gtttcaaaga ctcttttgag tgaaccttct tgggcaagga aataaatcaa gactgcaaaa
    39781 ctggctacca taccgacaaa ggcagcaaag gttgattggg taacggctgc tagataatct
    39841 cctgaaccga gcttcataat gataaaggtt gctaggagca tccagataac acgaatgacc
    39901 tgctcagcaa tttggctcat ggcatagggt ttgaggttat tcatcccttg gaaaaatcct
    39961 cggataacac tcatagacgg gaaaatcaag actccccaag ccaagctttg catgattggg
    40021 atcaagtctt tgcccacgcc agacaagtct gctagccaag gagcaaagac atacaagact
    40081 aaagcaaaaa ccaggcctag tcctgtcata aagcctaaga aactccgaat cagggcaaag
    40141 ctatgctctt cttctcgcat ggtattatac ttggcaactt gcttggccac cgcaactgga
    40201 atccccgctg ttgaaaccaa caagaaccaa gcatagatat tgtaacccat ggtaaagaga
    40261 ccatttgcct tagctgcata agcccccatc cagatgtacc aagggataat gtaaacagcc
    40321 ccgagtaggc gactgataaa gttactagcc gttagccaag cagtcccccg taacatctgg
    40381 gcctgctggt gattgttttc gtgcgacata gattcctcat tcaattttga tagctaggaa
    40441 aaactcctta tcttccatta taaacttttc cttgttactt gtaaatttac gactttcggt
    40501 ttacaataga aagtatgatt aagattgaaa ccgtattaga tattttaaag aaagatggcc
    40561 tttttcgcga aattattgac caaggtcatt accactacaa ctacagcaaa gttatttttg
    40621 atagcatcag ctacgacagc cgaaaagtaa cagaagacac tctttttttc gcaaaaggcg
    40681 ctgcctttaa aaaagaatac cttctttctg ctataacaca aggattagct tggtatgtag
    40741 ctgaaaagga ctacgaagtc ggtatccctg tcatcattgt gaacgatata aagaaagcca
    40801 tgagtttgat tgccatggag ttctatggta atccacagga aaaactcaaa ctccttgcct
    40861 ttactggtac taagggtaag acaacagcag cctatttcgc ctataacatc ttatctcaag
    40921 ggcatagacc tgctatgttg tcgaccatga acacaactct tgatggcgag actttcttta
    40981 agtcagcgtt gacaacccct gagagtattg acctctttga catgatgaat caggctgtgc
    41041 aaaatgaccg tacccacctc atcatggaag tctccagtca agcctatctg gtcaaacgtg
    41101 tctatggtct aacctttgat gtgggagttt tcctaaatat cagcccagac catatcggcc
    41161 cgattgaaca ccctagcttt gaagactatt tctaccacaa gcgtctcttg atggaaaaga
    41221 gccgagcagt catcattaac agtgacatgg accacttctc agtcttgaaa gaacaggttg
    41281 aagatcaaga ccatgatttc tatggtagcc aatttgataa ccaaatcgag aattccaaag
    41341 cctttagctt ttcagctacg ggtaaactcg ctggagatta tgatattcaa ctcattggca
    41401 acttcaacca agaaaatgca gttgctgctg gacttgcttg tctccgtctc ggagcaagtc
    41461 ttgaggacat caaaaaaggc atcgctgcaa cccgcgttcc tggtcgtatg gaagtcctca
    41521 ctcagaaaaa tggagccaag gtcttcatcg actatgccca caatggggat agtctgaaaa
    41581 aactcatcaa tgtggttgaa actcatcaaa ccggaaagat tgctctggtt ctgggatcaa
    41641 caggaaacaa gggagaaagt cgtcgtaagg actttggcct cctcctcaat caacaccctg
    41701 agattcaagt ctttctgact gctgatgacc ctaactatga agacccaatg gccattgcag
    41761 atgaaattag tagctacatc aatcatcctg ttgaaaagat tgcggatcgc caagaagcca
    41821 tcaaggcggc aatggctatc acaaatcacg aattagatgc agttattatt gcgggtaagg
    41881 gagtcgattg ttaccaaatc atccagggca agaaagaatc ctacccagga gatacagccg
    41941 tcgcagaaaa ttatttataa gaatagaaaa aatcaaggga aaatgaaacc cttgattttt
    42001 tcctattatt tagtaaaaac gtttttcaaa ccttcaacgg caccttctac agcacctttt
    42061 gcgtcttcta caacgtcttt tgccttagca actgtttttt caacagctcc ttcaagttct
    42121 gtcttgctgt ctccagtaac tttaccaaaa ccttctttga cagcgcctgt tgcttgttcc
    42181 aatttgtttt caagtgacat atgattgtct cctttagttt attccgatat gtgttaccgg
    42241 ttacatatag tttataccga atactaagga aagtcaaaca atgtgctcag aaacaagaaa
    42301 tcacgctaag tagaaagtta atctctcctt atcaaaatcg atagccaact catactttct
    42361 atcttcattt tgcacaatat agcctaagac aaccaaactg tccacaaaga tatcacggca
    42421 tttctgcata agctggtctt ttttgagaaa tttcaacaaa aaagccgtca tatacttgag
    42481 ggcatactca ggattaacat ctcctaaaat gtcatagagc tcctgctgtt tttctgtcaa
    42541 aggatactgc tgtttgacct tgtaaaaata attggacagg gtcattttaa tgcgcgcaaa
    42601 gtccgtcttt tcaactaaaa tagctgcatt gatttgattg cgcaattccg tctcaaaact
    42661 ctgctccaac aaggcttgat agaccggact agcttctctg acaaaaatct cttgatccag
    42721 ttcaagacta tcaagtgatt caagcgtagg aaaattgagg taatagcgct tattttcacg
    42781 tagaatcaag cctgccttta tatactcttc catgagttta tcaactgcaa catctggaaa
    42841 ttgagcctta atttcccgta gaatcacatc ctcatactgg tccagatagc ggatcaattc
    42901 tccaaaaatg gctgtctcgt caaacgagat ggattaaaaa tctgaatcat gaagatccct
    42961 ttctttacat tgtaacagag gcgatgctgc caactgacta ggattggtac cagcttggtt
    43021 cagaggaaca ggcagaccta gttctatgta atactccctc caaaaatcac taatctcctg
    43081 ctccccatct ccaaatttca taggaatagt ttcaaaaata ggtaggattt ctgctatata
    43141 ctgggagcag tagaaaccag ctgcatctgg atagaaagaa gcattgtagg gtgctccaag
    43201 atgtttgcaa gctctttcct tcaccgactg gatatccatt tctgggtaaa catagaggtc
    43261 gtataaatga ttggactcaa agaagtctgc cggttcttga cagacaacac cagcctgtcc
    43321 actagcatga taaatcatcc catccaaata aatggcaaca tggctatagt tacctgtgga
    43381 agtctggatg gcctgtccca tgtctgaccc atctctcaca aaaatcaaat cgccattttc
    43441 taacatactt cactcctaga aaaaaggagc cgaaactcct ttcgatataa ggcaaactag
    43501 actttccgat tttgagctga cacccaaaat cttacgcatt aaagctttca gtcaattgag
    43561 gtaccacttg tttcttacgt gaaacggcac cagcaaggaa ggcatgattg ttttcaagtt
    43621 tgaagttgaa agccgcttcg accttgtcca tattggcacc aagagccaag atttctgagt
    43681 ttgagttgac gatatctgta atcatcaaga caaagtcaga gtagccgttt gattcgttgg
    43741 cagcttgcat tgcagcttca atttctgctt ggcgttccaa aacttcagcg atgtcaactg
    43801 tgttcacttg ggcaacacgg acattatttc cgttgagttc aaaagtctta gcatcgatgt
    43861 caatcaattc ttcagcagat ttgctagcca agttggtacc agctttcaac attgctaaac
    43921 catattcttc caagttcaca ccagccaatt cagccaattc aggagcaatg attttatctg
    43981 ttgggtgtgt tgttggtgat ttcaaaagaa gggtatctga aatcaaacct gaaagcatca
    44041 aacctgcaat ctctttaggc acagctacac catgttcttt gaacatacgg taaacgattg
    44101 aagacgctga tccaactggc tccaaacgca tgtaaagtgg gcttgcagtt tcaaagttag
    44161 ccacacggtg gtggtctaca acaccataaa cttctacttc agcgatatct gatacagatt
    44221 gttggaattc attgtggtca gtcaagataa cttgctctgc cccctctgct ttggcagaag
    44281 tgataatacg tggtgcttcc acaccaaaat agttcaagac aaaggctgtt tcttcatttg
    44341 gagttccaag ggcaacagct tccgtatcca aaccgtaagc ttcttttgca aggtaggcaa
    44401 aagctacaga tgacccgatg gcatctgagt ctggattttg gtgaccaaat actagaatct
    44461 tggacatgat aatacctcat tttgtttatt ttctttattg tagcattttt ttcgcttttt
    44521 gacaaaggta agaggagtca aaggactccc cacgattctt caaaataact gagtaaattt
    44581 ctatcttgat tttcagataa aaattcttcc ttctgtggcc tcttcttacg cttgagaaga
    44641 gcttcagccg acatggcttc ttccttactg gcaaaacctt gagcatagat aagtttgact
    44701 ggcaagcgtg ctcgtgtata tttggctccc ttcccactat tgtggatagc gaggcgtctt
    44761 ctcatatcag tcgtatagcc tatatagtag gatccatcac gacactccag aacgtacata
    44821 taagccttat gatccataat aaatctcttc gatttcgggc gtataagagc catcatcatt
    44881 gtggacaatc aaaggaggta agaccttaaa gccacttgtt gagccatcct tgatcgcctc
    44941 aatcaaaagc atattggctt ccttttctct ttttggataa acaaactgca ggcgcttagg
    45001 ggctagatta tgtcgtttta acgtatccaa aatatccaga agtcgatcag gacgatgaac
    45061 catggccaaa cgcccattag acttgagaat actctgggca ctacgacaga tttcttccaa
    45121 attagtcgtg atttcgtgtc gagccaagag ataatgttca ctctcgttca gattagaata
    45181 aggatccacc ttgaaatagg gtggattaca caaaatcata tccaccttac tcccctgaat
    45241 gtgagcaggc atatttttca aatcatcgca gatgacctgc atttgctcct ctaatccatt
    45301 caaacggaca gagcgttcag ccatatccgc caaacgctcc tgaatctcaa cagacaatat
    45361 ctgtgcttga gtacgagtgc tagcaaaaag ccccactgct ccattcccag cacagaaatc
    45421 cacaatcaac cccttcttag gaaaacgtgg aaatcgtgat aagagaacac tatccaccga
    45481 atagctaaaa acctctctat tttgaatgat tttgatatct gtcgaaaaga gctggttaat
    45541 gcgctctcct gattttaata attgttcttc ttccatggtc ctattatagc aaattcatat
    45601 taacattaca aaaaatataa aactctaaac tacttcttct tttttaaatg gtgcagggct
    45661 tctccagtcc agattggtag cattcgtcga aagggagcaa aaccgtagtt aaagcggtcg
    45721 cttgaaaagc gtctccgtct aggaaactgg tacttttttt cctccaaagt gcggatagaa
    45781 agactggctt tccccgtaaa ttcatctaaa tccactacct gaacttgaac ctcttcatcg
    45841 actttcaagg tttcatgaat attttcaata aatcctgtcc gaatctctga aatgtgaatc
    45901 agccccgtat cacccgtctc taactcaaca aaggcaccgt agggctgaat ccctgtaata
    45961 cgccccttta gcttatcacc gattttcatc ttagtcctcg atttcaatag tttcaattac
    46021 aacatcttca actggcttgt ccatagctcc tgtctcaaca gcagcaatgg catccaagac
    46081 agcgtaagat gcttcatcag ctaactgacc aaaaaccgtg tgacggcggt ctaggtgagg
    46141 tgtcccacct tgattggcat agatttctgc aatcggttct ggccaaccac cacgagtaat
    46201 ttctttctta gaataaggta ggtgttggtt ttgcacgata aagaactggc tgccgttggt
    46261 atttggacca gcatttgcca tggaaagagc accacggata ttgtaaagct cttctgagaa
    46321 ttcatcctca aaagattcgc cgtagattga ctcgccaccc ataccagttc cagttgggtc
    46381 tccaccttgg atcataaagt ccttgataat acggtggaaa atgacaccat catagtagcc
    46441 atcttttgaa agagatacaa agttagccac tgttttagga gcatgttcag ggaaaagctt
    46501 gatacgtaag tctccgtgat tggtcttaat agtcgcaaga ggaccttcta ctgtttcaat
    46561 gtctacttgt ggaaaatgca attctttttc taccatacca aatacttcta aggcatcaaa
    46621 aatgccatct tcttctaatg tttttgtaat ataatctgct ttttctttga ttttatcatg
    46681 agaaattccc atggcaacgc tgattccagc ataatcaaag agttccaagt cgttgagacc
    46741 atctccaaaa accatgacct tctctggttt caagccaagg tgttccacaa ccttttccac
    46801 ccccgtcgct ttggagcctg aaatcggcac aatatcagac gaatgttgat gccaacgaac
    46861 catgcgaagt ttgtctgaga gactgtcagg caagtgcaag tcatctccct tatcttcaaa
    46921 agtccacatc tgatagatat cttctttttc atggaaatcg ggatctacat ctaagtcggg
    46981 ataaattgga ttgatagctt cactcatcat atcggtgcga atcgacaact tggcatcatg
    47041 actcccaacc aagccatact caattccttc ttgcttagcc caagagatat actcctcaac
    47101 atctgacttt tcaatctgat gctgataaat gacctgacct tttttatctt cgatataagc
    47161 cccattcaaa gttacaaaaa agtcaggctt gagatcacga atctctggaa caacaccaaa
    47221 aatgccacgt ccagaggcga ttcctgttaa aattcctttt tcacgcaact gtttaaaaac
    47281 agtgggaatt gtagttggaa taaaccctgt ctttgaattc cgcaatgtat catcaatatc
    47341 aaaaaagaca atcttgatct tctttgcctt gtatcttaat ttcgcgtcca tctcactacc
    47401 tctttcaatc taactctttc cattatatca taaagtaggc aaatccccta ttttcaaaaa
    47461 gtttatcatt tttattttaa tttcttggat gagaaaaaag acatatttat gaaaaagctc
    47521 catcgtgctt ttaatgtgtt ctcttgtttt caaactcgta aaaagggagc cactgagcct
    47581 aactcgctct ctcatttcaa agtttgtgaa aaaagaccca ttggggtctt aattcgcttt
    47641 cttgttttca agctcatgaa aaagagaccc aaccgggtct tttctttaat cttcgtttac
    47701 gaaaggcatc aaagccatta cgcgagcgcg tttgatagct gttgttactt tacgttggtt
    47761 tttagctgaa gttcctgtta cacgacgagg aaggattttc ccacgttctg aaacgaaacg
    47821 gctaagaagc tcagtatctt tgtaatcaac atattcaatt ttgtttgctg cgatgtaatc
    47881 aactttttta cggcgtttga atccgccacg acgttgttga gccatgtttt ttctccttta
    47941 taagtttagt tgtccattag aatggtaaat catcatctga aatatccaat gggtttgttg
    48001 ctccaaatgg attttcatta cgtgaaaagt ctggtactga atttgtaggt gctgaatagt
    48061 ttgcagttgg tgcagagtaa gctccacctg tgtgaccctc acgcacacta cggctttcca
    48121 acatttggaa attctcagcc acgacctctg tcacgtagac acgttgtcct tgctggttat
    48181 cgtaactacg agtctggata cgacctgtca ccccgataag tgagcctttt ttagcccagt
    48241 tagcaagatt ttcagcctgt tggcgccaca taacgacatt tataaaatca gcctcacgtt
    48301 caccattttg actcttaaat gtacggttta ctgcaagagt aaaagtcgca actgctacat
    48361 ttgatggggt ataacgcaac tcagcgtcac gtgtcatacg ccctacaagt acaacattgt
    48421 taatcatagt ttaccttctt acgcgtcaat tttgacgatc atgtgacgaa gaatgtcagc
    48481 gttgattttt gaaagacggt caaactcttt aagagctgca tcgtcatttg cttcaacgtt
    48541 aacgatgtgg taaagtcctt cacggaaatc ttggatttcg tatgcaagac gacgtttttc
    48601 ccaagttttt gattcaacaa cagttgcacc gttgtcagtc aaaatagagt caaaacgtgc
    48661 taccaaagcg tttttagctt cttcttcaat gtttggacga atgatataaa gaatttcgta
    48721 tttagccatt gatatgttcc tccttttggt ctaatgaccc caagactttg caaggggtaa
    48781 gtgaggttcg ctcacaataa actattatac tagaaaaaat ttttttacgc aagtaaaaac
    48841 actagaattc gaaaaaacgc cacatgggcg ttttcctgtt cttatggttt gatacggtgc
    48901 aacatacgtg ggaatggaat agcttcacgg atatgttttg ttcctgctgc gaaggttacc
    48961 atacgttcga taccgatacc aaatcctccg tgtggaactg taccgtattt acgaaggtca
    49021 aggtagaatt catattctgt acgatccatg ccaagttcat ccatcttagc gacaagggca
    49081 tcgtaatctt cctcacgcat agacccaccg ataatttctc catagccttc tggagcaagc
    49141 aagtctgcac aaagcacgcg ctctggattt ccaggaactg gtttcatgta gaaggccttg
    49201 atggctgctg gatagttctt gacaaatgtt ggcacaccaa agtggtttga aatccaagtt
    49261 tcgtgtggtg acccaaagtc atcaccatgc tcaagatgct cgtagtcagc atcttcatca
    49321 ttttcatgct cttgcaagag gtcaatggct tgatcgtaag tgatacgttt gaatggctct
    49381 gcaatgtagc gtttcaagag ttctgtatca cgttccaagg tttccaaggc ttgaggcgcg
    49441 cggtcaagaa caccttgtag aagagctttc acataagctt cttgcaagtc aagcgactca
    49501 tcatgtgtca agtatgagta ctcagcatcc atcatccaga actcagtcaa gtgacggcgt
    49561 gtttttgatt tttcagcacg gaaaactgga ccaaagtcaa agacacgacc aagagccata
    49621 gcccctgctt ctaggtaaag ctgacctgat tggctcaagt aggctggcgt tccgaagtag
    49681 tcagtttcaa agagttctgt agaatcttct gccgcatttc ctgaaagaat tgggctgtca
    49741 aacttcataa aaccgttctt gtcaaagaac tcataagttg catagataat agcgttacgg
    49801 atttgcaaca cagctacttg cttacgagag cgtagccaca agtgacggtt atccatcaaa
    49861 aagtctgttc cgtgttcttt tggtgtgatt gggtagtctt gagattcacc gatcacttcg
    49921 atgtctgtga tgtccaactc atagccaaat ttagaacgtt cgtcctcttt gacaatacct
    49981 gtcacataaa cagacgtttc ttggctcaag cgtttgataa catcaaactt ctcaagtccc
    50041 acttcttcac caaatttttc gacaaagttt ggtttaaaag ccacaccttg aaagaaggct
    50101 gttccatcac gcaattgtaa gaaagcgatt ttcccttttc ctgatttgtt ggcaacccaa
    50161 gcgccaatcg tcacttcctg accaacatag tcttttacat caataatcgt tacacgtttt
    50221 gtcattattt ttccttttct tttttattct ttatggcaaa ccacctctat attgttccca
    50281 tccaggtcaa tcataaaagc agcataataa atcggatgct cacttcgata accaggaacc
    50341 ccattgtctc gcccacctgc ctctaagcca gcctcataac aagcctgaac ttcttcctta
    50401 ttttctgcta aaaaagcaaa atgaacagga tcttgtgttc cctgagtcag ccaaaaatca
    50461 ccaccaggat gagggctgtt cggggataga aaactaatta gagaactagt cttaaaagcc
    50521 aatttatagt ccaaaggagc gagaaaactc ctataaaatc cttctgaaat ttgtaaatcc
    50581 tttaccttaa tctcaaaatg atcaatcatt ctcactaccc ataaatgctt tcaagcgttc
    50641 gactgcttct ttaagcgtgt ctaggtctgt cgcatagctg aggcggacat tttctggtgc
    50701 tccaaatcca gctcctgtta ccaaggccac ttcggcttct tctaagatag cagttgtaaa
    50761 gtctgtcaca tccgtgtagc ctttcatctc catggccttt ttgacatttg ggaagagata
    50821 gaaggcccct tgtggtttga ccacttcaaa tcctggcacc tctgcaagga ggggatagat
    50881 ggtattaaga cgttcctcaa aggcctgacg catgctttct acagtatctt gctcacctga
    50941 tagagcctca actgctgcat attgggctac tgctgacgga ttcgaagttg tttgacctgc
    51001 aatcttggac atggcagcga taatgtctgc ttctccaacg gcataaccaa tccgccaacc
    51061 agtcatggca taggttttag acacaccatt gatgaccact gtttgcttgc gaatcgcttc
    51121 cgataggcta gaaatcggtg tgaactcatg accattataa accaagcggc catagatatc
    51181 atctgctagg atgagaatat cattttctac agcccagttt ccaattgcca agagttcctc
    51241 acgggtgtaa atcatacctg tgggattaga tggcgaattc agcaccaaaa ccttggtctt
    51301 gtcagtgcga gctgcttcta actgctctac ggtcacctta aagtgattgt cttccttagc
    51361 agaaacaaag acgggaacgc cttctgccat cttgacctga tctccatagc taacccagta
    51421 tggggttggg atgatgactt catcacctgg attgaccaca gccataaaga aggtatagag
    51481 agaatatttg gctcccgcag cgactgtcac ttgatttgac gctacagaat agccgtaaaa
    51541 gcgctcaaag tagctattga ccaccgcctt aagctctggc agacctgagg ttactgtata
    51601 aaaagaagca cgcccatctc gaatcgatgc aatggcggca tcttggatat ttttgggagt
    51661 agtgaaatct ggctcaccca aggttagaga caaaatatct ctaccctcag ccttcagtgc
    51721 tttggcacgg gctccagcag ccaaagtcac actttcttcc atttctaaaa cacggttgga
    51781 tagtttcata ggccctcctt attgaccaat gctcctgttt caaaatctac tagataaaaa
    51841 tcagatcctg acttaacttc ccagattggc ttgtcttgat aacgaccaaa ggttatcttg
    51901 tcaatctcgc cagctccctt ttccttagaa accgtttctg ctttttcttg tgaaataccc
    51961 tgatttagct gataaacgta aatcttatgg tcatctttac caatcaggac agcaagcgct
    52021 tcttgctgtt tattacgacc aagaacgctg taataagatt ccaagccatt gtataaatca
    52081 acctgatcag cctgctctaa tcctgcatac tgctgagcta atttttctcc ttcactttta
    52141 gctgtttgat agggtttcat gctaagagaa accatataca gaaaggaagc actgataacc
    52201 acaaacaaaa tcgtcatccc tagaccatac tgccacagta gattattttt tgctttgttt
    52261 tgtctttttt tcactcgtct attttaccat ctattaagct ttattacaag tgaatataag
    52321 aatactcttc gaaaatctct tcaaaccatg tcagctttat ctgcaacctc aaagctgtgc
    52381 tttgagcaac caattctatt tctcccttca aacaaaaccg attttgaaag tgaaacagtt
    52441 cttacttttt cagtcacaaa tgactagagt ttccgaaatt ttacaatttt caaataaact
    52501 ctgagcaaat ttcttgcaag ttcttttgtt ttgttgtaat atattttata acaacgagag
    52561 agttctcgaa attttaagaa aaaggagaca catcatgtct aaaaaagtat tatttatcgt
    52621 cggatcacta cgtcaaggtt ctttcaacca ccaaatggcg ctcgaagctg agaaagcact
    52681 tgctggtaaa gcggaagtta gctaccttga ttattcagcc cttcctctct tcagccaaga
    52741 tttggaagtt ccaacacatc cagctgtagc tgctgctcgt gaagcagttc tcgttgcgga
    52801 tgctatctgg attttctctc cagtctacaa cttctctatc cctggtacag tgaaaaactt
    52861 gcttgactgg ctatctcgtg cccttgactt gtctgataca cgtggcgttt ctgcccttca
    52921 agacaagttt gtcacagtat catctgtagc caatgcaggg cacgatcaac ttttcgctat
    52981 ctacaaagac ctcttgccat ttatccgtac acaaggcgtt ggtgatttca ctgctgcacg
    53041 tgttaatgac tctgcctggg cagacggaaa attggttctt gaagaaacag tcctaaactc
    53101 acttgaaaaa caagctcaag acttggtcga agctatcaag taactaacac tcaataaaaa
    53161 tcaaaaagca aactaggaag ctagccgcaa gctactcaaa gcactgcttt gaggttgtag
    53221 atagaactga cgaagtcagt aacatatata cggtaaggcg acactgacat ggcttgaaga
    53281 gattttcgaa gagtataaca taataaaagc gaacaagact acttttctga cgctcagaag
    53341 actagcttgt tcgctttttt ctcatttata aactaaaata gctgatgata catattgcca
    53401 aatacaaaat atctgatttc tatacttcct ttacaaaaac caatccctgt ggttgtgaca
    53461 aatcttctcg gtaaacaaat ccagcaaagt tcaagcgacg tgcttccccc acagtttgta
    53521 cttgattttc tattaaagct gttagaaagg ccccgcgcgc tttcttggag atagttgagt
    53581 gaatcttcag ctgaccgcct ctatcctcca tgaatttgaa ggtcaccatc tttgctctga
    53641 tttccttaga aaatacagtc tcaaactctg atgacaagag agagaaaatc acttcttcct
    53701 tcttcagagc ttcatcatag actgccttcc aatggctctt caaagtctta ccagcaactt
    53761 ttaatttcat caaaaaatcc aaacggtgag gagccatggg tgacaaggct ggaacaacac
    53821 cgtacaaagc cgaggtaatg aagacatgat tttcaagata atcttgttcc gcctcggtca
    53881 gcttatctct cttaatgttg cggtacataa gcccatcaaa aagtttcaag gctggatagt
    53941 gttgagtagt ttgccttttc aaagcttgga tattttgaaa ttcttccgcc gctttctcag
    54001 ctgatacctt gtagaaactc tccaattgac tggcagaata gagagccaag gcatcaagca
    54061 cggcctgact ttctggtttt aaagaaattg cctcgatact tggcaagtct gtgttcattt
    54121 cttttgctgt tgggattaaa attttcatat tgatagtgta gcatattttt tagccacaac
    54181 caagaaattc atttgaaaaa cctcggtttg accgaggttt ttctatttat ttgggccatc
    54241 ctaaccagac agccacgaga acaagggctg tgccagctaa acttgttaag atagataaga
    54301 atttatcttt tttctccttg aactgagaaa aacctatctt caaagcgagc agtccgagta
    54361 gcattgaagc aaccatcaaa taaaaaccca tttctttgtc ctccattagg cttaatttac
    54421 cttattataa catatacttt ctgaaaaaaa cctattttta ccgtagctta aaggtcttga
    54481 gataattgtc ttttcctact tgaccttcga aggttttacc attttcaagg taaggaaggt
    54541 catcggatac tgaagccttg accttgtata tcttgccatc aactttaaag aagtagacag
    54601 tgtctccctt gataacagct gatttgaggt ctgctactac tccattgatg ctttctgtcg
    54661 ttgcattgtc aatttcaagg tcgtttttat tggcatactt gctgagcatc tcttccactg
    54721 tagtagcaac gataacattt tggtactcga ctgcgtctac cagggcgtac tctttgacca
    54781 agccagcatt gtccttcaag cccatgatgt agagaggctt gtcattgagg ttgatgagga
    54841 ttgggaaggt tgctttgtag gatttctcct gaacagcacc ttctgctgat tcacgggctg
    54901 attcttctgt cgcagaagcc aagctatact tagtgatttc tcctgttcgc atattttcaa
    54961 ggatgaaacc aagattactc tcatccgcat tagccgacgt cacacctgtg tagagataga
    55021 tgtcattacc gatagacaag taattatagc ccttggtagt ctgggtcacg tttttcttgg
    55081 aaatcatggc attcaagaaa ccgtccttgt acttgccgtt gtagttgatt tgctcaatgg
    55141 tttcctctgc tggatagatc ctgtccaccc attctggaac atctgataag ctgtattcct
    55201 tggtttctcc atttgtagca tccaagataa tgactgaagc aggacgagga acagcaagtc
    55261 caaattgctt ttggtaaacc gttgctacat agaaaggatt gccctcatcg tccacctcaa
    55321 aagatggagt tttaaagatt ttggtcgggt acttcaagcg caggtgacgt ttgacatcac
    55381 ggttaaaata ctccgagtct gaatacttga ttggtgtctt caagtccacc aaatccgcat
    55441 ttccagttac catgtccacc ttgatatact caccgattcc cttggcttga ttgttaaacc
    55501 atttgatagg gtctgcatat tctagtggtg tgacccgata aggtttccca tcaattgtca
    55561 attgggtata ggtatctgcc gctacgtatt gcgacacctt atcggttagg gaacccaagt
    55621 agcggtctcc aattttttca gcagtacttc tatctaggat aggaacctta ctggtgtcac
    55681 tcctaggaaa ttcagtaaag tctttttccg taaccgtgac tacattggca taatttttag
    55741 cctgaaacat gctggaagtt accaaggaaa ccaaagctgc caagagaaga attcctccaa
    55801 tcgaagctaa cagaattttc cctaaccgat tgattttgaa accctcaaga tttaaggcag
    55861 cttccgcctt accgtggcgc acatgaaccg ttttgacaag gtttatcccc ttgccaaagc
    55921 caaataagat tgccacaact aacaaatgcc cacagaggaa gaagagaaat tcccagctgg
    55981 tcaggttaag gggcggtaaa aagatatacc aggtcgttgc gataaaaata agttcaaaga
    56041 ctattcgttt catttgcttt cctcctaaat gattcgtcct tccaagtgat ccagctcatg
    56101 ctggcaaatc tgagctggga agcctgtcaa ggtaatggtc tgttcctgcc acttgctgtc
    56161 acgataggca agccttatgg tttcataacg cttagttgat ctcacaccta ccaaggacaa
    56221 acagccttct tctgcctcat aagatccttc aaaggacaga agcactgggt taaacatgac
    56281 cacgggaacc aagccaagat taaagataat cacgcgcttc tgcaccccaa tcatattggc
    56341 agctagacca acacaggtat cacgatttgc taagagtgta tcctgcaaat ctctggcaag
    56401 ataaaggtcc tcctgacttg ccggctgaga cacttgagat aaaaataaga tatccttcac
    56461 aattttcttt tccacttcct cacactcctc ttgcttttta ctatattata gcaattatag
    56521 cacaaaagcc gataactgca aaccctttcc ctcaactgta gcaaaaagcc atccgaagat
    56581 gacttttttg ctatttaatt tctgtataag ttacttccaa tccacgctta acagctggac
    56641 gattggcaat tttttctgcc cattttacta gattttgata acttgaggca tccaagaatt
    56701 ttgcagaacc ttggtaaaga tttccttgaa ctaactgtcc ataccaagac cagatagcaa
    56761 tatctgcaat cgtatagtca ttgcctgcaa tataaggttt ctgagccaat tccttatcca
    56821 ataaatccaa ctggcgtttc acttccatcg taaaacggtt aataggatat tccaattttt
    56881 caggagcata attgaagaaa tgtccaaatc ccccacctag aaaaggtgct gcacctgctt
    56941 gccagaatag ccaattcaaa acttctacct tttccacagg attacttggt aaaaaggctc
    57001 caaatttctc agcaaggtaa agaagaatat gagcagactc aaagactctt acgctttcag
    57061 tacctgactg gtccaataag gctggaatct tggaatttgg attgagcttc acaaagtctg
    57121 agccgaattg atccccatcc atgatagcaa tcttatacaa gtcgtaagcc gcttccttaa
    57181 aaccagcttc tagtaattct tccaataaga tagtaacctt cacaccattt ggtgttccca
    57241 gtgaataaag ctgaaaagct tgttctcctt ttggcaagtt ttgttcgaaa cgggcacctg
    57301 ctgttggtct gtttagcccc gtaaaagctc cttgattact agcttcatcc tgccatacgg
    57361 tcggtaattg atatgctgac atccgaaacc tcccttaaat cgcattcttg tcaaaaccga
    57421 gtttgcgttg aataaactta acgatttcga cgatgataat cattgagaag cttccagcca
    57481 taacaattcc ccattgtgac aagtctagtt tggttacgtg gaagattcct tcaagcggtt
    57541 ctacaacgat tgttgccatg agaaggataa aggataccaa gatggaccag ttaaaggtct
    57601 tagacttgaa tgggccaact gtcaagatgg attggtagac agacttgaca ttgtaggcat
    57661 ggaagagctg aatcaaacca agggttgcaa aggccatcgt tagggcatct gcatgaatag
    57721 catgattgtc acccacatga actgggtaag caatcgcaag gccataaaca ctcataacaa
    57781 gagctgcttg gagtacacct tgataaatga tagaactcaa aacaccacct gagaagaagc
    57841 ttgccttgcg tccacgtggt ttatgattca tgacgccagg ttctgcaggt tcaacaccaa
    57901 gagcgatagc tgggaaggta tccgttacca agttgatcca caaaagatga accggctgta
    57961 agacatccca accaaacaag gttgatagga agatggttaa tacttcagca gtattagcag
    58021 aaagtaggta ctgaatagtc ttttgaatgt ttgagaagac cttacgtcct tcttccactg
    58081 cgacgataat agtcgcaaag ttatcatctg caagaatcat atcagaagcc cccttagaaa
    58141 cctctgtacc agtgattccc ataccgatac cgatatcggc tgttttcaga gctggcgcgt
    58201 cattgacacc gtcacctgtc atggcaacga ctttaccttg tttttgccaa gccttgacga
    58261 tacgaacctt gtgttctgga gacacacggg cataaacaga gtattgacca acgacttttt
    58321 caaattcttc atctgacagt tcattgagtt cagcaccagt taaaacgtga ccttctgtat
    58381 cgtttgcgtc aatgattccc aaacgtttgg caatggcttc cgctgtgtct tggtggtcac
    58441 ctgtaatcat aattggacgg attcccgctt ccttagccac acgaacagcc tcagcggctt
    58501 caggacgttc agggtcaatc atcccaatca aaccagtaaa aattaaatca ttttcaagct
    58561 cttcagaagt gagattttct ggaatactat cgataatctt ataagcacct gcaaggacac
    58621 gcaaggcttg atgagccatt tcagaattgt ttgtatgaat gagatttgta accttctcat
    58681 caatcggagc aatatcccca gccttatcac gaagaagaca acgttttaag agttggtctg
    58741 gcgcaccctt gactgctaca aggaaacgac catctggcaa tgggtgaact gttgacatga
    58801 gcttacggtc agagtcaaat ggcaattcag ctacacgagg atatttctct aagaaacctt
    58861 tgacatcata gcccttgtcc aaggcatatt ggataaaggc tgtttcggtt gggtcaccaa
    58921 tcaagttacc ttccacatcg attttcgtat cattggccaa gacaactgaa cgaagtagtg
    58981 gcatttcaag acctagttca atatcatcag ctgagtcatg tagaaccgca tcgtagaaga
    59041 ctttttcgac tgtcatcttg ttcatagtca gcgtaccagt cttatcagaa gcgatgattt
    59101 cagttgaacc aagtgtttca actgctggca acttacgaac gatggaatgt cgtttggcca
    59161 aaacttgagt accaagagaa agaacgatgg taacgatagc aggaagtcct tctggaatgg
    59221 ctgcaacggc aagggcaaca gaagtcaaca actcaccaag tggatttttc ccttgaatga
    59281 agacacccac tacaaaagta acaagggcaa tgaccaagat agcataggtc aagaccttag
    59341 aaaggttgtt caagttttgt ttgagtggtg tatcagtctc atccgcatct tgaagcatac
    59401 cagcaatatg accaacttca gtgtacatac ctgtattgac aacaacaccc atcccacgac
    59461 cataggttac gtttgagttt tggaaggcca tgttgacacg gtcaccaata ccagcatctg
    59521 tcgcaagctc gactgacaag tctttttcga ctggtacaga ttcacctgtc aaggctgctt
    59581 cttcaatttt aagagagttg gcttctatca aacgtaggtc cgctggtacc acgtcacctg
    59641 cttcaagggc aacgatatcg cctggtacca attctttaga gtcaatctct gccatgtgtc
    59701 catcacgaag aacgcgggca actggactag acatggattt gagggcttca atagcttctt
    59761 cagcttttcc ttcttggtaa acaccaaagg cagcgttgat gataaccaca gctaggatga
    59821 taatggcatc tgcgatatct tccccaccag aagtcacgac tgacaagatt gctgccgcaa
    59881 ctaggatgat aatcatcaaa tccttaaatt gctcgatgaa tttgaccaag attgatcgtt
    59941 tctcgccttc ttcgagttca ttgtgcccaa attcggcaag gcgcttttcc gcctcacttg
    60001 atgacaaacc ttgctcggtc gcatccacag cctgcaagac ctcttcaggg ctctgagtat
    60061 aaaacgcttg gcgtttttgt tcttttgaca tgtgtctcct ccttgacatt gtgtgcaaaa
    60121 cagactctct ttctgtcata tcttttcacg acaaacaaaa agagacctgt taatcataac
    60181 aagtctcgct gtttaagata gggccggaaa gcatactttt cagcataaaa ttcggaatga
    60241 cgacactatc acaggtttct gccagctact cccttgagta gtaccattat accaaatttt
    60301 ggggagtttt caaagagtaa aaactgcctt atttgaattt ttccttgaaa accagtataa
    60361 tggtagaatg ctatgtgact agaaaggaag ttgaatgaag caatctatct caaatctcaa
    60421 gttagctgag cgtggagcca ttatcagtat ttcgacctat ttgatcttgt ctgcagctaa
    60481 attagcagct ggtcatctcc ttcattcatc cagtttggtg gccgatggtt ttaataacgt
    60541 atcggacatc attggaaatg tggccctctt aatcgggatt cggatggcgc gccagcctgc
    60601 agaccgtgac caccgttttg gtcattggaa gattgaagat ttggcaagct tgatcacttc
    60661 tatcatcatg ttctatgtcg gtttcgatgt tctaagagat accattcaaa agattctcag
    60721 tcgggaagaa acggtcattg atcctcttgg tgcaactcta ggaatcattt ctgcagcgat
    60781 tatgtttgtg gtctatctct acaatactcg cctcagtaag aaatccaact ccaaggcgct
    60841 gaaggcagct gctaaggaca atctttctga cgctgttacc tcacttggaa ccgccattgc
    60901 catcctagct agtagtttca attatccgat tgtggataaa ctggttgcta tcatcatcac
    60961 tttctttatc ttgaagactg cctatgatat cttcatcgag tcttccttta gtctttcaga
    61021 tggctttgac gaccgcctgc tcgaggacta ccaaaaggct atcatggaaa ttcccaaaat
    61081 cagcaaggtc aaatcgcaaa gaggtcgcac ctacggtagc aacatctacc tggatattac
    61141 actagagatg aatcctgact tgtctgtttt tgaaagccat gaaatcgcgg atcaggtcga
    61201 gtctatgctg gaggagcgtt ttggcgtctt tgataccgat gtccatatcg aaccagcacc
    61261 tatccctgag gatgaaattt tagacaatgt ctataaaaaa ttgcttatgc gtgaacaatt
    61321 gattgaccaa ggaaaccaac tagaagaact cttgactgat gattttgtct atattcgcca
    61381 agatggagag cagatggata aagaggctta taagaccaaa aaagagttaa attctgctat
    61441 aaaggacatt caaattactt ccatcagtca aaaaaccaaa ctcatctgct atgagttaga
    61501 tggtatcatc cataccagta tctggcgtcg ccacgaaacc tggcaaaata tctttcatca
    61561 agaaaccaaa aaagaataga gaaatccttt catgagacgg gatttttcta ttcttttata
    61621 ctcaataaaa atcaaagtgc aaattaggaa gccggtcaca ggctgtactt gagtcggcaa
    61681 tgtgaagccg acatagtttg cactttgatt ttcgaatagt cttaactatc aaattcactg
    61741 agatactcat agcgttcgta tttttcaagg agtgcttcat ttttctcatc caattctttt
    61801 tggagagtag tcagcttacc aaagtcagag ccgttagcct gcatttcctc ttcaatagca
    61861 gcgatacgtt tttccaaggt ttcaatatca ccttcaatac ttgcccactc ctgcttttct
    61921 tggtaggtca tgcgtttctt gtcttctcga accttgacca ctttttcctt ttcgaccttt
    61981 tgcacttgat tggccatatc tgtttcaaaa gctttttcat caagatagtc ggtgtaatga
    62041 ccaaagaaag gacgaatctt gccatcctca aaagcgagaa tcttggtcgc taccttatcc
    62101 aagaaatagc ggtcgtgact gactgttaaa acgggacctg caaaaccttg caagaaattc
    62161 tctaagactg tcaaagttgc aatatctagg tcattggttg gctcgtctaa aagaagaaca
    62221 tttggttttt ccaaaagcag tttgaggaga taaagacgtt ttttctcacc ccctgacaat
    62281 ttctcaatca aggttccatg cgtcgaacgt gggaaaagga actgctccag caactctgca
    62341 atcgaagtcg tagaaccgcc actggtcttg acctcttctg ccacttcctg caggtaattg
    62401 ataactctct tgctttcatc caaaccctca atttgctgag agaaataggc gatgcgaaca
    62461 gtttccccaa tcacaacttg tcctttagtt ggctcaagac ttcctgcaat caagttgagc
    62521 agggttgatt ttccaacacc attgtcccca acgattccga tacggtcttt ggcctgcacc
    62581 aagagattaa aatcttgcaa aataggcttg ttttcatagg caaaggaaac agcctgaaac
    62641 tcgatgactt tcttcccaat ccgactggtt tcaaagttca tggtcaagtc tgtctcagca
    62701 ctactgcctg aaacttcctt tttcagatca tggaatcgat tgatacgggc ctgctgcttg
    62761 gtcgcacgcg cctgcggttg tctgcgcatc caggccaatt cttgtttgta gagttgttct
    62821 tttttgtgaa gaagagccgc gtcgcgctca tcctgttccg cctttaggcg aacatagtcc
    62881 tggtaatttc cctggtactc ggtcaagcct gctcgctcca actcgaaaat ccgtgttgac
    62941 aaagcgtcta agaaataacg atcgtgagtg ataaaaagga cggtcttctt agaatttttc
    63001 aaaaagaggg tcagccactc aataatcgca atatccagat ggttggtcgg ctcatccaaa
    63061 agcaaaaggt cgtggttgcc aagtaagact tgtgccaact gtacccgtct tctcagacca
    63121 cctgacaatt ccccaacagg agtagataag tcttgaatgc ccaatttgct aagaacggtc
    63181 ttgacctgac tctcgatttc ccaagcttgg agagagtcca tctctgccat gacacgttcc
    63241 aaacgcgcct gcttgtcctc actatagtcg agcataatca attcatactc acgaatgagc
    63301 tggatttcct tgagttcact agatagaacc gtatccaaaa ctgtctttct atcatcaaaa
    63361 tcaggatcct gagtcaagta accaatctgg taatcatttt tagctgaaaa aggactgaca
    63421 tccccatcaa atccagaaac accagaaagg acgtccaaaa gggtggtctt gccagtccca
    63481 ttgacaccga ttaaaccaat tctgtctaag tcatggataa taaaggaaat atccctaaaa
    63541 acggtcttgt caccaacgga tttacttagt ttttcaacga taaaatcact cattttttct
    63601 ccctcaggta agcatggatg gcttcacgat tattctccaa ttctccatcg acaatggcaa
    63661 actcaatctc tgttaaaatc tctcccaagt ctgggcctgg ctgatagcca tattccttga
    63721 tcaaaatacc gccgttgatt tggatttctt tcttatcatg aatagtcaag ctctggtagg
    63781 tttctttaat gacttgtggg ttgacttctt ttccttgagc ttgacgaaga ttttcagcct
    63841 gtaaaagtaa atccaagtca aagcgataac aatcacgctt actcaattct ccattttcac
    63901 gcagagccaa aataatcagc aaatcctgaa cttgcttggc aaactggcgt gaggtcttcc
    63961 aagatttcaa aaatgactgc gcattttcaa tctccaaagc ccatagtaaa gccgcccagg
    64021 cttgttcaga ggattcaaaa gtaaaatcag tctccaaatc aaacagtctg ttgagcttgt
    64081 cctggctaga tgccatatca gggagatagt cataagcttg actctcaatc atggaagcca
    64141 agccccttct ccaaaatgga gccagcaaga gtttatcaaa ctcgacgaag gtacgctcta
    64201 cagaaatttt ctccaaaagc ggcgtcaagg tcttcatagc tttaaatgtt tctggctcaa
    64261 gtgcaaaacc aagactagcc tgaaaacgga aaccacgcat aatccgtaaa gcatcttcgt
    64321 tgaaacgctc actagccact ccaactgctc gcaagacttg cttttccaaa tcttctaaac
    64381 catggaacaa gtcaacgatt tctcctgtct catccaaggc aaaggcgttg actgtgaaat
    64441 cacggcgttt gaggtcttct tctagcgagc gcacaaagga aaccgcactg ggtctgcgat
    64501 agtccacata gacatcctct gtccgaaagg ttgttacctc atactcctca tccccatcta
    64561 agaccaagac ggttccatgc tcgattccga tatcggctgt tcgcggaaaa atctgcttgg
    64621 tctcttctgg ataagaagac gtcgcaatat ccacatcgtg gatagggcta tggagaaggg
    64681 catctcgaac agagccccca acaaaataag cctcaaagcc tgcttcttta attttttcta
    64741 atactggtaa agccttctga aattcagaag gcatttgcat taatctcata ataagtgttc
    64801 taatccatag acaagctcat gacgcttgac aacttcttta attcccaaat tgactcctgt
    64861 catgaaggag atgcgatcat aggagtcatg acggagggtc aacccttctc cctgattgcc
    64921 aaagatgact tcctgatgag ctaccaagcc tggcaaacga actgagtgga tgcgcatacc
    64981 atcaaagtca gcaccacgag caccagcaat cagctcttcc tcatctgctg caccttgctg
    65041 aatggactct cgaacctctg ccatcaactc agctgtttta atggctgttc cactcggagc
    65101 atcctttttc ttgtcatgat ggagctcaat aatctccaca tttgggaaat atttggcagc
    65161 ctgcgtcgca aattgcatga gtaagacagc acccaaggca aagttagggg caatcaggcc
    65221 acccaagtct tgggcacgag aaaattcttt tagctctgca atttcttcac tcgtgaaacc
    65281 agtcgttcca actactggag caaagccatt ttcaagagca aaacgtgtat tttcgtaggc
    65341 aacagctgga gtagtaaaat ctacccagac atccgcttca aaaccagcta aatcagcctt
    65401 atccttgaaa acaggaatac cctgccattc tgactcagac tcaaaaggat ccaaaactgc
    65461 caccaagtcc aagtctggat cagtcaatac catctgacaa gcagcctggc ccatctttcc
    65521 cttaaaaccg gcaataatta ctcgaatact catctctact cctgtctaag atacaaagtc
    65581 cgtaagaaca caaagtgaaa ataggaattc caatcaagaa gtgtctactt cttggaagaa
    65641 ctatcttttt cacacagggt tccaggcgtg ttcaattatc aagatacaaa ggaccttagc
    65701 tgcctctgaa aaatagggaa tggcactgac tttccacgaa aggcaagaca ggcatctttt
    65761 ttcaagaggc aggtagtccg tgttcaattt ctaagataca aggcatctta actagcctag
    65821 aagcgccaac taaatcactg gaatataacc cagagcaata cttcctgctc ctaggtgcgt
    65881 tccaatgaca ctaccaaatg tagcaagtga aacatccgaa cccaagccaa aatcaagcaa
    65941 gtgctgacgc aattcttcag ccttttcagg agcattccca tgaatgacaa tgacccggta
    66001 ttgacctgaa gccgttgttt ccttgataat ttcaattaag cgcttggtgg ccttcttttc
    66061 agtacgaact ttttcgtaaa cttcaatcac accttgatcg ttaaaataaa ggattggctt
    66121 aatgctaagc aaattgccca aaatggcagc cccatttgaa aggcgtccac cttttaccaa
    66181 atgatccaag tcatctacca tgataaaggc tgacgtacgg ctgatttgaa tggctagctt
    66241 atcctgaatg ctggcaaaat catcgccctg atcacgccaa ttaaagacgc tttcaaccat
    66301 gatgcctagg ggagcacttg taatcaaagt gtctgggaaa gcaatggtta agccctcata
    66361 gtcatcgacc atatactgga tattttggta aaaacctgaa attccagaag ataggaaaag
    66421 ccccaaggca tgtgtatagc cttgttcttt gagcgaagtt aagatttcat ctaacttggc
    66481 aatacttggt tgactggtct taggaaattc agaagcctga gccatttttt ggtaaaattc
    66541 ctcagcagac agattgatgc cttcgacata ttcctcacca tcaatattga caggaatatc
    66601 caagacaaac aagtcttctc tttgcaaggt ctctgcactg agataagcag aggaatctgt
    66661 gaaaacagct aatttcatat tagaactcca aattaattcc tggtaagtct aatgcaattt
    66721 cagtcacttc gtaagtcaaa cgattgagca tgttcaaaca tggacgagcc aaggtttcca
    66781 cctcttcttg gttcaattca cttggttcat tgacaatacg gccatcgata tggtttactt
    66841 gtgagattgt tccactaatg acaaacttat caaatacaat cataaagctc aagatgacaa
    66901 tcaaggaagt cacttgattt tcttggtcat gttggagcaa ttggaaattc acatccacct
    66961 tggtttcagg agctccattt tcattttccc attcaaaatt acgcgcatca aaatgatact
    67021 gactaacaaa ttcttgttca cgtttaagat tcatgtcttt ctccatcggc tacaatatta
    67081 taagctattg tatcataatt ttttattttc atctagtttt ctaggattta gtcaatccca
    67141 atttcagcac gaactacatc tgtgatggta tcaacatagt agtctacttc ttctgttgta
    67201 ggcgcttctg ccataacacg caagaggggc tctgttccac ttggacgaac aaggatacgg
    67261 ccgttccccg ccatttcttc ttccatcttc tcgatgatgg ccttgatagc tggcacttcc
    67321 atggcctttt ccttcatgac gttttccact cggatattaa ctaatttttg tggataaatc
    67381 gttacttctg ccgccaactc tgataagctc ttaccagttt ccttcatgat tttagtcaat
    67441 tgaactgctg ataattgacc atcacctgtg gtattgtaat ccatcaagat aacgtgacca
    67501 gactgttcac caccaaggtt gtagcctgat tttctcattt cttcaacaac gtagcggtca
    67561 ccaactgcag taactgcctt gttaatacct tcgcgattca aggccttgtg gaaaccaagg
    67621 ttagacataa cagttgtcac aattgtattt tgagccaatt gtcctttttc agaaaggtat
    67681 tttccgatga tgtacataat cttgtcacca tcgacgatgt caccattctc atcaacagca
    67741 atcaagcggt cactgtctcc atcaaaggcc aaaccaatag ctgacccact ttctttgacc
    67801 acttcttgaa gggcttctgg atgtgttgaa ccaacattaa ggttgatgtt aagaccgtct
    67861 ggtgtttccc cgataaccgt caattgggca ccaaggtctg caaagatttg acgggcactg
    67921 gtagaagctg ctccattagc tgtatccaag gcaaccttca ttccatcaag aggagttcca
    67981 gttgaaacaa gatatccttc atacttacgc aagccttctg gataatctac caagattcct
    68041 aagccttctg cacttggacg aggaagagtg tcttcctcag catctagcaa ggcttcaatt
    68101 tctgcttctt tttcatcatc tagtttgaag ccatcaccgc caaagaactt gattccgtta
    68161 tcaagggctg ggttgtggct agcagaaatc atgacaccgg cacttgctcc ttcagtttca
    68221 accaagtaag ctactgctgg tgttgcaagg acaccaagtt tgtatacgtg aatccctact
    68281 gaaaggagac ctgccaccaa ggccgattcc agcatttccc ctgaaatacg tgtgtcacgt
    68341 cctacaaaga ctttcggcgc ttccgtttca tgttgactaa gaacatagcc tccaaaacgt
    68401 cctagtttaa aggctaattc tggtgttagt tctaggttag cttctccacg gactccatca
    68461 gtcccaaaat atttacccat tgttataaaa tccttttcta tttttaattc gtttttgaac
    68521 tagttgcttt cgttgacgaa gatgtctccg atgaactgct tgtacttgaa tttgatgtgc
    68581 ttgaacttgg tgctactggt tttgtagtca ccttcattat tgtatcaaac ggagtgataa
    68641 ctgccggtaa gacaacacca ttgcggtcga ttgcctgcaa aggtactgaa ccactgtaat
    68701 tacctgttat acgttcgcta gttggcaaga cagcgataat cttatcaatt ctatccaatg
    68761 tctcttggtc actcgtaata gacacttctt tatctgacac catgacattt tcaatttgta
    68821 cccgactatc aatttgacta gggtcaatct ctggtacaat ctttacctta tccttctgag
    68881 ccttcttacc aatcttgact gtaatttttt gcggagtcgc cacagcggtc agcccattgg
    68941 gtaaatcttc aatgctcaaa ggaacttcaa tcgttccaac accggcatct gttaggtcag
    69001 cagtaacctt gaatttacgt gtactttctt gcatttcact agctagcgat aggcgatttg
    69061 caccagtcaa gaccactgat acttctgaag caaaaccgct aataaaatac ttatcactat
    69121 tatagcgtat gtcaataggg acatttgtta ctgtattagt ataggtttcc gtttttacct
    69181 gcctagcact ggtactgttt tgaaaattcg tcgccgtagc atagacaaat aagacacaag
    69241 caaaaaagag tgaggatatg atatataaac tatttttttt catgtttcca tcctcctagc
    69301 aatcgttctt taaaactaag acccacttcc tcttttggaa gtaagatttc acgtaattct
    69361 gtttcaaatt catcaagtgt taggttgtgc ttaaaccttc cattataggt tatcgaaatt
    69421 cctcccgttt cctctgatac gacaaaagtc aaggcatctg agacttctga taaaccgata
    69481 gccgcccggt gtctggtccc aaattccttg gaaatccctg tgttttttgt caagggcaga
    69541 taggcagacg tcacagcgat acgttcttct ttgataatca ccgcaccatc atgtagggga
    69601 gtgttgggaa taaaaatgtt aatgagaagt tctgcagaaa tcttagcatc caagggaatt
    69661 cctgtcgaaa tatactcctg caaggtacgt acacgctgaa tagcaaccaa ggccccgatt
    69721 ttacgaggac tcatgtattc aacagactta acaaaggcac gaatcatctg ttcctcagca
    69781 ctaatagggg cattggaaaa aaaatctgtc gctcttccca aacgttccaa accagtccga
    69841 atctctggag agaagataac aaccgccgca ataaccccat aagtaataat ttgattgatt
    69901 aaccaagaaa tcgtagtcaa accaatcata tttgcaagga tttgagctaa aataaacacc
    69961 aaaactccac gtaccaaaat cataatcttg gttcctgcaa tagcttttgt aaaatggtat
    70021 aaaatataag caacaatcaa aatatcaatc agattgatag ctatcgtcca tggacttgca
    70081 aacaaactgg tccaatattg cagattggat aattgttgaa aattcatccc tgatatcctc
    70141 cctatcaaaa cactttcgtc ctattatacc attttctggc atttttttcc ctatcctagt
    70201 ccattttaca ttgaacaaaa atatgataaa ataaactgac tagaaaaaac aaaggagaaa
    70261 ctatgtctca actctatgat attaccattg tgggtggtgg tcctgtcggg ctttttgcag
    70321 ccttttatgc ccacctacgc caagccaagg ttcaaatcat cgactctctt ccccagctag
    70381 gtggacaacc tgctattctc taccctgaaa aggaaatcct agacgtacca ggcttcccaa
    70441 acctgactgg agaagagttg actaaccgct tgattgaaca gctaaatgga tttgataccc
    70501 ctattcatct caatgaaacg gttcttgaga ttgacaaaca agaagaagaa tttgccatca
    70561 caacttctaa aggaagtcac ctgactaaaa cagttatcat cgctatgggt ggcggtgcct
    70621 tcaaaccacg tccgctggaa cttgaaagtg ttgagggcta tgaaaatatc cactaccacg
    70681 tttctaacat tcagcaatac gctggtaaga aagtgacgat tcttggcggg ggagactcgg
    70741 ctgtggattg gactttggct tttgaaaaaa tcgcaccaac tacccttgtt caccgcagag
    70801 ataatttccg tgccttggaa cacagtgttc aagccttgca agaatcatct gtaaccatca
    70861 agacaccatt cgtccctagc caactccttg gagatggaaa aacgcttgat aaacttgaaa
    70921 tcacaaaagt caaatctgat gaaactgaaa ccattgacct agaccacctc tttgtcaact
    70981 atggtttcaa atcttctgtc ggtaacctta aaaactgggg gctcgacctc aaccgtcaca
    71041 agattatcgt caacagcaaa caagaatcca gccaagcagg tatctatgct atcggtgact
    71101 gctgctacta tgacggaaaa attgatctga ttgcgacagg tctaggggaa gctccaactg
    71161 ctgtcaacaa cgctatcaac tacattgacc ctgaacaaaa agtacaacca aaacactcta
    71221 ccagtttata aaaaagaacc acgagtcaca taggattcgt ggttttataa ttcatccgca
    71281 tttaaaaata cctttacatc gttttactat atcttacaat accttttaaa acagctatat
    71341 tttgagcttt taaataaatg tttttacatc attttacaga gatttacgac acttttgccc
    71401 cttttttgcc ccttttttaa aacaaaaaaa ccgcaagcct gagcctgcgg tgaaagaaca
    71461 atttagaaag tttcctttct atttatttaa ctgtaatcaa gccatctggc tctactgtga
    71521 agtctggctt atctgccagt gttccgtctg gtttgaggta gtaccagcct gttccgtctg
    71581 cggactggac gaaggcgttt gataccatag caccttcttt agcgtctaag tagtaccaag
    71641 tgttcttgta cttgacccag cctgtcttca tggcaccttc tacatcaaaa tagtaccact
    71701 tctcagcgat tttcttccag cctgtggcca tttcgcctga ttggtcaaag tagtaccaat
    71761 taccgtctgt gtgcttcttc cagcggtctg aaagcatata gcctgagcca tcgaaataat
    71821 accaggtacc gttgattttc tcaaacttat cttttggata agagccgtct gagtgtacgt
    71881 accagtagcc agtgccattt ttctgccagc ctgttgcagc tctcaagccg ttttcgatgt
    71941 cttgcttaaa ctgttcacgg ctaatgcccc atttagcaag atatggatat ggatccacat
    72001 ggtctgagtg gttgtttggt tggttattgg tacagtattc atgcgtcttg atacctgcca
    72061 agtcgtctgt atcaagagtc ttcggcaagc ctgcttcgtc cgctagattg cgtagcaatt
    72121 cgatatagag gcggtagtcc gtcatgaact cttctttagt tgaatggctt tcaatcagtt
    72181 caaccgctgc gtaactctca gcattccaac cgcccccaac atcccaactt ccgttgttca
    72241 caggtcctac ctgcatgatg cgaccgttcc caacaacgtg cgagaaaaaa cctaattctg
    72301 ggtctttccg ccagtgataa tccgcttcat tctgtacggt tgagttacgg ttgcctgttg
    72361 aatgggcgtg tacttgtcga taaggctgca ccccaacctg tggcaagcct gtacgtagtc
    72421 tgtttctatc gatatccatt ccctatcgtc ctttccatgc gtcattcatc tgcttcactg
    72481 ctgactctac gaaggtgtct aagtctttgt cagtcatgct aatattgtat tttgtaagct
    72541 cagcacggac tttagcgcga gcctgtgcca gtttttcatc tcccttgtag ccagtttcag
    72601 cagctacttg ctcaacggca tttactgcat ttttggccaa gatttcaacg attttgat
//
LOCUS       DAVKMJ010000004        68992 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000004 DAVKMJ010000000
VERSION     DAVKMJ010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68992
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.004"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..216
                     /locus_tag="VW348_000237"
     CDS             <1..216
                     /locus_tag="VW348_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745220.1"
                     /translation="LWYYLNESGSMATGWVKDKGLWYYLNESGSMATGWFTVSGQWYY
                     TYNSGDLLVNTTTPDGYRVNANGEWVG"
     gene            complement(695..844)
                     /gene="rpmG"
                     /locus_tag="VW348_000238"
     CDS             complement(695..844)
                     /gene="rpmG"
                     /locus_tag="VW348_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU9745221.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(860..1042)
                     /gene="rpmF"
                     /locus_tag="VW348_000239"
     CDS             complement(860..1042)
                     /gene="rpmF"
                     /locus_tag="VW348_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEU9745222.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            complement(1194..1394)
                     /locus_tag="VW348_000240"
     CDS             complement(1194..1394)
                     /locus_tag="VW348_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU9745223.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            complement(1397..2404)
                     /locus_tag="VW348_000241"
     CDS             complement(1397..2404)
                     /locus_tag="VW348_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU9745224.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            2595..4625
                     /locus_tag="VW348_000242"
     CDS             2595..4625
                     /locus_tag="VW348_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU9745225.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            4629..4913
                     /locus_tag="VW348_000243"
     CDS             4629..4913
                     /locus_tag="VW348_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9745226.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            4926..6272
                     /locus_tag="VW348_000244"
     CDS             4926..6272
                     /locus_tag="VW348_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU9745227.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFITKPSAKEE"
     gene            6276..7133
                     /locus_tag="VW348_000245"
     CDS             6276..7133
                     /locus_tag="VW348_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU9745228.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            7130..8062
                     /locus_tag="VW348_000246"
     CDS             7130..8062
                     /locus_tag="VW348_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEU9745229.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSYSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     SVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSSLCELFSDDGMTKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            8295..9998
                     /gene="ilvD"
                     /locus_tag="VW348_000247"
     CDS             8295..9998
                     /gene="ilvD"
                     /locus_tag="VW348_000247"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEU9745230.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(10159..10239)
                     /locus_tag="VW348_000248"
                     /pseudo
     CDS             complement(10159..10239)
                     /locus_tag="VW348_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(10297..10638)
                     /locus_tag="VW348_000249"
     CDS             complement(10297..10638)
                     /locus_tag="VW348_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU9745231.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            10762..11613
                     /gene="rgg"
                     /locus_tag="VW348_000250"
     CDS             10762..11613
                     /gene="rgg"
                     /locus_tag="VW348_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEU9745232.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSMDERVELTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            11806..13053
                     /locus_tag="VW348_000251"
     CDS             11806..13053
                     /locus_tag="VW348_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEU9745233.1"
                     /translation="MKLLFRNPAYRILILSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFVGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            13131..14420
                     /locus_tag="VW348_000252"
     CDS             13131..14420
                     /locus_tag="VW348_000252"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEU9745234.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKEA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVSYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFVAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            14411..14491
                     /locus_tag="VW348_000253"
                     /pseudo
     CDS             14411..14491
                     /locus_tag="VW348_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            14761..15075
                     /locus_tag="VW348_000254"
     CDS             14761..15075
                     /locus_tag="VW348_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745235.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            15085..15291
                     /locus_tag="VW348_000255"
     CDS             15085..15291
                     /locus_tag="VW348_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9745236.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            15291..15488
                     /locus_tag="VW348_000256"
     CDS             15291..15488
                     /locus_tag="VW348_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745237.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQGDQFVWLYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            15491..16225
                     /locus_tag="VW348_000257"
     CDS             15491..16225
                     /locus_tag="VW348_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEU9745238.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            16237..16878
                     /locus_tag="VW348_000258"
     CDS             16237..16878
                     /locus_tag="VW348_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9745239.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            16896..17126
                     /locus_tag="VW348_000259"
     CDS             16896..17126
                     /locus_tag="VW348_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745240.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            17478..19241
                     /gene="aspS"
                     /locus_tag="VW348_000260"
     CDS             17478..19241
                     /gene="aspS"
                     /locus_tag="VW348_000260"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEU9745241.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            19219..20160
                     /locus_tag="VW348_000261"
     CDS             19219..20160
                     /locus_tag="VW348_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU9745242.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(20370..20450)
                     /locus_tag="VW348_000262"
                     /pseudo
     CDS             complement(20370..20450)
                     /locus_tag="VW348_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(20586..21572)
                     /locus_tag="VW348_000263"
     CDS             complement(20586..21572)
                     /locus_tag="VW348_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9745243.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            complement(21582..22382)
                     /locus_tag="VW348_000264"
     CDS             complement(21582..22382)
                     /locus_tag="VW348_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEU9745244.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PGQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            complement(22643..23485)
                     /locus_tag="VW348_000265"
     CDS             complement(22643..23485)
                     /locus_tag="VW348_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9745245.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            complement(23487..24779)
                     /locus_tag="VW348_000266"
     CDS             complement(23487..24779)
                     /locus_tag="VW348_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9745246.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            complement(24890..26161)
                     /locus_tag="VW348_000267"
     CDS             complement(24890..26161)
                     /locus_tag="VW348_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9745247.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            26711..28228
                     /gene="malQ"
                     /locus_tag="VW348_000268"
     CDS             26711..28228
                     /gene="malQ"
                     /locus_tag="VW348_000268"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEU9745248.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            28254..30512
                     /gene="glgP"
                     /locus_tag="VW348_000269"
     CDS             28254..30512
                     /gene="glgP"
                     /locus_tag="VW348_000269"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEU9745249.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(31557..32129)
                     /locus_tag="VW348_000270"
     CDS             complement(31557..32129)
                     /locus_tag="VW348_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745250.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTTIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     SAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(32752..33600)
                     /locus_tag="VW348_000271"
     CDS             complement(32752..33600)
                     /locus_tag="VW348_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU9745251.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            33752..34030
                     /locus_tag="VW348_000272"
     CDS             33752..34030
                     /locus_tag="VW348_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745252.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            34032..36095
                     /locus_tag="VW348_000273"
     CDS             34032..36095
                     /locus_tag="VW348_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU9745253.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIKLMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(36173..37429)
                     /locus_tag="VW348_000274"
     CDS             complement(36173..37429)
                     /locus_tag="VW348_000274"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEU9745254.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            37571..40036
                     /locus_tag="VW348_000275"
     CDS             37571..40036
                     /locus_tag="VW348_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU9745255.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            40101..41012
                     /locus_tag="VW348_000276"
     CDS             40101..41012
                     /locus_tag="VW348_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU9745256.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            41242..41940
                     /gene="dapD"
                     /locus_tag="VW348_000277"
     CDS             41242..41940
                     /gene="dapD"
                     /locus_tag="VW348_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEU9745257.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            42008..43138
                     /locus_tag="VW348_000278"
     CDS             42008..43138
                     /locus_tag="VW348_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEU9745258.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            43150..43689
                     /locus_tag="VW348_000279"
     CDS             43150..43689
                     /locus_tag="VW348_000279"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEU9745259.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMEFVVYDPQQLVKTSFALLEPQ
                     GDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            43673..44350
                     /locus_tag="VW348_000280"
     CDS             43673..44350
                     /locus_tag="VW348_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEU9745260.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(44422..45321)
                     /gene="galU"
                     /locus_tag="VW348_000281"
     CDS             complement(44422..45321)
                     /gene="galU"
                     /locus_tag="VW348_000281"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEU9745261.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(45343..46359)
                     /locus_tag="VW348_000282"
     CDS             complement(45343..46359)
                     /locus_tag="VW348_000282"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU9745262.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            46581..46984
                     /locus_tag="VW348_000283"
                     /pseudo
     CDS             46581..46984
                     /locus_tag="VW348_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823968.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            complement(47099..47524)
                     /locus_tag="VW348_000284"
     CDS             complement(47099..47524)
                     /locus_tag="VW348_000284"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9745263.1"
                     /translation="MNNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(47592..48242)
                     /gene="phoU"
                     /locus_tag="VW348_000285"
     CDS             complement(47592..48242)
                     /gene="phoU"
                     /locus_tag="VW348_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEU9745264.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(48257..49009)
                     /gene="pstB"
                     /locus_tag="VW348_000286"
     CDS             complement(48257..49009)
                     /gene="pstB"
                     /locus_tag="VW348_000286"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEU9745265.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(49011..49826)
                     /gene="pstA"
                     /locus_tag="VW348_000287"
     CDS             complement(49011..49826)
                     /gene="pstA"
                     /locus_tag="VW348_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEU9745266.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(49819..50682)
                     /gene="pstC"
                     /locus_tag="VW348_000288"
     CDS             complement(49819..50682)
                     /gene="pstC"
                     /locus_tag="VW348_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEU9745267.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFIANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(50800..51675)
                     /locus_tag="VW348_000289"
     CDS             complement(50800..51675)
                     /locus_tag="VW348_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEU9745268.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGKYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(51842..53173)
                     /locus_tag="VW348_000290"
     CDS             complement(51842..53173)
                     /locus_tag="VW348_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEU9745269.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMVLTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(53174..53881)
                     /locus_tag="VW348_000291"
     CDS             complement(53174..53881)
                     /locus_tag="VW348_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9745270.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(53965..54267)
                     /locus_tag="VW348_000292"
     CDS             complement(53965..54267)
                     /locus_tag="VW348_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU9745271.1"
                     /translation="MTADEIWYFHAESPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTRY"
     gene            complement(54254..54475)
                     /locus_tag="VW348_000293"
     CDS             complement(54254..54475)
                     /locus_tag="VW348_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEU9745272.1"
                     /translation="MNKSYFNPLAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINL
                     AGKGRALYTSIYFLLRRNESFTFSPIDSR"
     gene            54437..54995
                     /locus_tag="VW348_000294"
                     /pseudo
     CDS             54437..54995
                     /locus_tag="VW348_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(55310..57001)
                     /locus_tag="VW348_000295"
     CDS             complement(55310..57001)
                     /locus_tag="VW348_000295"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEU9745273.1"
                     /translation="MNTKELIASELSSIIDSLDQEAVLKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            57137..57583
                     /gene="argR"
                     /locus_tag="VW348_000296"
     CDS             57137..57583
                     /gene="argR"
                     /locus_tag="VW348_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU9745274.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            57634..60168
                     /gene="mutS"
                     /locus_tag="VW348_000297"
     CDS             57634..60168
                     /gene="mutS"
                     /locus_tag="VW348_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEU9745275.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDCEGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            60315..62009
                     /gene="patA"
                     /locus_tag="VW348_000298"
     CDS             60315..62009
                     /gene="patA"
                     /locus_tag="VW348_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEU9745276.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLDALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELFGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(62340..62609)
                     /locus_tag="VW348_000299"
                     /pseudo
     CDS             complement(62340..62609)
                     /locus_tag="VW348_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            62801..64567
                     /gene="patB"
                     /locus_tag="VW348_000300"
     CDS             62801..64567
                     /gene="patB"
                     /locus_tag="VW348_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEU9745277.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAHQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPIMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            64706..65395
                     /locus_tag="VW348_000301"
     CDS             64706..65395
                     /locus_tag="VW348_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU9745278.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            65399..65578
                     /locus_tag="VW348_000302"
     CDS             65399..65578
                     /locus_tag="VW348_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745279.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            65565..66914
                     /locus_tag="VW348_000303"
     CDS             65565..66914
                     /locus_tag="VW348_000303"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEU9745280.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAVVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            67038..68498
                     /locus_tag="VW348_000304"
     CDS             67038..68498
                     /locus_tag="VW348_000304"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEU9745281.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            68512..68946
                     /locus_tag="VW348_000305"
     CDS             68512..68946
                     /locus_tag="VW348_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU9745282.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERATLFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT        20233 a        12830 c        14921 g        21008 t
ORIGIN      
        1 ttatggtatt acttaaacga atcaggttca atggctactg gttgggttaa agacaaaggc
       61 ttatggtatt acttaaatga atcaggttca atggctactg gttggtttac agtttctggt
      121 caatggtact atacctataa ttcaggagat ttattagtaa acacgactac acccgatggc
      181 tatcgagtca atgctaacgg tgagtgggta ggataggtat ccattagcta aatctaatca
      241 ttctgaacta aaaaatcttc ttacatatgt aggaagattt tttggattct caaaactagt
      301 ttaaaagact acgctattta aaccaatttt aagaatggat atataaggat attcagaaat
      361 ctagttggtc aacttttgta ttttgaatat accttagatg gtgacgatgt cttggtatat
      421 ctggtactca cttacatatt ctaacttatt ttaactaaga tacaactgta gttggtgaat
      481 ttgctacaaa tagtgtagag gcgttatttg aaaaatatac aaaaaaggaa ccccaactta
      541 catttgagtt cctcttgctt ttaattgtcc gaatccgtat tcttatttca ataatgtagt
      601 cattcgaatg atttcccttg caatatagtg aaattaacaa aaagaaaaaa cgctgatcaa
      661 gcgtttttct tctgtattga ttcgtattga atgcttactt cacttctgta aacacaacgt
      721 gtttgcgaag ttttggtgag tatttcttca attgaaggcg gtctggagtg ttacgtttgt
      781 ttttagaagt aaggtacaag cgttcaccag attctttgtg ttcaagtgta atatttacgc
      841 gcatagtatc tcccttctat tattcagctg atgcagcttt agcgatttta cgtcctttgt
      901 agtatccttt aagtgataca cggtgagaac gtgagtaatc tccagtagtt tcgtcaaagt
      961 ttacagatgg agctgttact ttgtagtgtg tacgacgttt gtttttcttc gcttttgaag
     1021 tgcgacgtgc aggtactgcc attttgattt ctcctttagg tatttatatt cgattcaatc
     1081 tactgatttt catcaaccat actaggataa cacatttttt ttgtaaagta aagttacttg
     1141 acaaaaaaag atgaaaaaat tctcctatcc gacacggcag acaggagaag gtgttaaata
     1201 tcaatctcaa atggttcgtc aatggtttct gatacgtatt ttccgtcttt tttccgttgc
     1261 ttgacacact ctgtgaggag atattctatt tgcccattga ctgaacgaaa gtcgtcttct
     1321 gcccatgatg cgagtgcagc gtataacttt gttgagagtc gaagggggat ctgctttttt
     1381 ttagcttcag ccatctttag taaagacttc ctgtgttgac aattggttgt gcatcatgat
     1441 tgccacaaag aacgacaagg agatttgaaa ccatggcagc ttttcgttct tcgtcaagtt
     1501 ctaccaattc cccttcattg agccgttcta gtgccatttc aaccattcct acagcaccat
     1561 ctacaatcat cttacgtgca tcaataatgg cagatgcttg ttggcgttga agcataacgg
     1621 cagcaatttc tggagcataa gctaggtaag tgatacgtgc ttcaaggatt tccaagccag
     1681 catcctcaac acgactttgg atttcttcac gaatacggtt agcaacaatt tcgctagagc
     1741 cacggagact accttcatct gcttgcccgt cacccgtagt atccacatta ggagacacat
     1801 cgtaaggata gatgcggaca atattacgga gggcgctatc acattgcaat gaaagatatt
     1861 ctttgtagtt atcaacgttg aagactgcct tagcggtatc gacaactctc caagttaccg
     1921 cgataccgat ttctacaggg tttcctaagc aatcattgat tttttgacga gaattgctca
     1981 aggtcatgac tttgagggaa atctgtttct tgccaatttc aagatttaca tcattgtcat
     2041 ttgatgattt agctcctaaa aaaggagatt ttgtgctaac atcaccactt tgtccaagtc
     2101 gagtgtggtt tgcagggttg actgctacgc tgaagggatt gacaaagtaa aaaccaggtt
     2161 ctttgatggt acctgtataa ttaccaaaga gtgtcagaac cagagcttcc tgaggtttga
     2221 caacttttaa accagcatga gctagacctg caattacgat tagtaaaggt ccgataataa
     2281 ttccaaaaat gttttccgaa ccaacaccca ttataaatat aaagatacca agtacgattg
     2341 tcaattcaat gagaatcaat gcgaatacac catttggttt tgaattgatg agtttttcag
     2401 tcataagaat gacctcctat tatttgatat ctaaatgata tcactttgtt tttaaaagtc
     2461 aatagaaagt tgaaaataat cactaaaaag tttcagccca ataatttctt ttaaaaggtg
     2521 agattatatt gtgctcaaat actcttttat tcttataatt tttacactat aattgtagtt
     2581 agaaaggaag agaaatgttt gattatagag cactagttat tttgatgact ttgatggatc
     2641 attgtgagct atcattatat gaattatctg ttaaggtgag cttacctata aaggaagtca
     2701 aagaaggaat agattattta gtgccttatc tagctaataa agggatagtg ctggataaaa
     2761 aacaaggtcg ctatagttta tcaaatcgta cgaagcagtc tttgacagat attattaagt
     2821 cggatgaatt ggttttacca aagtcgactc gcttagcttt aatctatctt tacacttttt
     2881 gccgattaga ttttatatcg aataatcatt accaagactt tttgaaagta agtaagaata
     2941 caaccttatc tgatattcaa tcattaagaa agattatgtt agataatgat ttggagctag
     3001 ggtacagtag agcaaaaggt tatactttac acggttcaga gtggaataag caccgcttag
     3061 cttttcaaat ggttagtgag ttgctggaat cctccatagg gatttggggt ttggattatg
     3121 ttttatccag ttgggggtat tcattaactt atgatttgat aaatcaggta gttaaagatt
     3181 attatgagaa gctacagcta gtacctattg ttaatcaatt aaaagtttgc cttttcggtt
     3241 tagtattcat tctgtgtagg tatcaaaggg atgttgaaag agtatgtctt tcagagacat
     3301 tagtatctcc tgttattcaa gatataacga ctattttatt ggatacagtg gttgatttgg
     3361 gaattataga tacggtgttt tctgaggatg attatcgcta tatcaccgtt ttattatcaa
     3421 gttgctttga aggtgaagta gatgttgctc cggtttactt taatcaatta acagaggcta
     3481 ttataagtag aatggaagat atttctttgt tacattttaa acaaagggaa ggattgagag
     3541 aaaatcttcg ccgccacctt ataccggctt actatagatt aaagttcggc ctacctagtt
     3601 caaatgaata tgtattgcat gttaaagaac attatcctga tttatttgaa ttagtcaaag
     3661 attctttgat gcccttgatg gacgctattg acaatcccat acctgatagt gaaacagcat
     3721 attttgttat ccatttcgga ggttatttaa agaaagcaga tactttgcct caaaaatgct
     3781 ataaagcagc aatcatttgt cctaatggtg ttagttcttc attgatgtta aaagagaatc
     3841 tattagcatt atttcctcaa attgagttta taggaacctc aaagattgat gatttacagg
     3901 tgaaagctag tagtgactat gatatggttt tttctaccat aaaggtggag acagaaaagc
     3961 caaattatct agtttcggtt atgatgactg aagagcaagc aatacaacta gtagaactag
     4021 tgttaaaaga ttttccgaat ttagagtatg gggattttga gattgaacaa atcctgaata
     4081 ttgtcaaaag atatggaatt attacacaag aattggaatt aagattggcg ttaaagaatt
     4141 atctttacca aaaaaatgat agaaaggaaa ttgtaccagt gctagaacaa ctcattacca
     4201 aagaaaccta tcaggttagt tcgcaaaaat taggatggaa ggaggcgatt cgtttagcag
     4261 ctaaaccgct tttggatcaa gataagataa ctgagaacta ccctgaggca atgattcaaa
     4321 aagtagaaga gtttgggcct tttattaatt tagggaaggg agtagcaatt cctcacgctc
     4381 ggccagatga aggtgtgaat gaaataggaa tgtcaatgtt agttttggaa gaaccgattt
     4441 atttattgga taatccagaa caagaggtaa gattgttgat ttgtattgca gccattgata
     4501 atgagagtca tttaaaggct ttgtcacatt taacaacaat tttaagagat aaaaatcatg
     4561 ttcaaacttt aatatcatca aaaaactatg atgacattaa aatgataatt aaacaggagg
     4621 attagataat gttaaaaatt ggtacagctt gtggttcagg attaggttca agttttatgg
     4681 tacagatgaa tattgaatct gtattgagtg atttgaatgt ttcggatgta gaagttgaac
     4741 attatgattt aggtggagca gatccaaatg cagctgatat ttggattgtt ggtcgtgatc
     4801 tagctgattc agctagtcat cttggagatg ttcgtatctt aaatagtatt attgatatgg
     4861 atgaactacg agaattaatt actaaacttt gtgaagaaaa aggacttata taggaggcta
     4921 gcgttatgat gaagttcata ttggatattg ttagtacacc agctatttta gtagctttaa
     4981 ttgcaatttt aggattagtt cttcagaaga agaaattacc tgatattatt aaaggtggaa
     5041 ttaagacctt tgttggtttc ttagttgtat ctggtggtgc aggaattgta caaaattctt
     5101 taaatccatt tggtaccatg tttgagcatg cttttcattt atctggcgtt gtgccgaata
     5161 atgaagcaat tgtagctgta gctttaacaa catatggctc agctactgca ctgattatgt
     5221 ttgcaggcat ggtgttcaat atcttaatcg ctcgttttac tcgatttaaa tatatttttt
     5281 taacagggca ccacactcta tatatggcat gtatgattgc ggtcatttta tcagttgctg
     5341 gctttactag cttgcctctt atcttactag gaggattagc actcggtatt attatgagta
     5401 tttccccagc atttgttcaa aaatatatgg ttcaattaac tggaaatgac aaggtggctt
     5461 taggtcattt cagttctttg ggatattggt tgagtggttt tactggtagc cttatcggtg
     5521 acaaatcaaa atcaacagag gacattaaat ttccaaagag tttagctttt ttacgtgata
     5581 gtactgttag tatcacttta tccatggcag ttatttacat tattgtagct atctttgcag
     5641 ggtcagaata tatagaaaaa gaaatcagta gtggtacaag tggtctagtt tatgctttac
     5701 aattagcagg tcaatttgca gcaggggtat ttgttatttt agcaggtgtt cgccttattt
     5761 tgggcgaaat tgttccagcc tttaaaggta tttcagagcg tcttgtacct aattcaaaac
     5821 ctgctttgga ttgtccgatt gtttatactt atgcacccaa tgcagttcta attggattta
     5881 tctctagttt tgttggtggt ttagtaagta tggcaattat gattgcttca ggaacggttg
     5941 ttatcttacc aggtgttgtg cctcatttct tctgtggagc gactgcaggt gtcattggga
     6001 atgcatctgg tggtgttcgt ggagccacta ttggagcatt tttacaaggt attttaatca
     6061 gttttcttcc agtcttttta atgccagttt tgggaggact tggtttccaa ggatcaactt
     6121 tctcagatgc agattttggt ctatcaggaa ttattttagg aatgttaaat caatttggct
     6181 cacaagcagg cattgtgatt ggtcttgttc ttattctagc agttatgttt ggagtatcct
     6241 ttattacaaa gccatctgca aaggaggaat aagggatgat tttaagtaaa aatagggaag
     6301 atgagttaag aaaatttgcg actaacatcc gattaaatac tcttagaaca ttgaatcatc
     6361 ttggattcgg acattacgga ggaagtctgt ctatcgtaga agttttagca gtgctttatg
     6421 gtgaaataat gccaatgact ccagaaatat ttgcagcacg agatagagat tatttcatat
     6481 tatcaaaagg tcacggagga ccagctctat acagtacact ctatttgaat ggtttctttg
     6541 acaaagaatt cttatattct ttaaatacaa atggaaccaa attaccgtct catcctgata
     6601 gaaatctaac gccaggcata gatatgacaa cgggctcttt aggacaagga attagtgttg
     6661 caactggact tgcatatggt cagagaataa gaaagagtcc cttttatact tatgctattg
     6721 ttggagatgg tgagttaaat gagggacaat gttgggaggc tatacagttt gcttctcatc
     6781 aacagttatc caacttaatt gtatttgttg atgataacaa aaaacaatta gatggtttta
     6841 caaaggatat ttgtaatcca ggtgatttcg tagaaaaatt ttcagcattt ggatttgaat
     6901 ccattagggt caagggttca gatattagag aaatttatga agggattgtc caattaaaac
     6961 agtcaaataa ttcatcacct aagtgcattg tattagatac tattaaaggt caaggggttc
     7021 aagagctgga agaaatgaaa tccaaccatc atcttcgccc tactgtagag gagagacaaa
     7081 tgttaacttc agttgtagaa agattaagtc aggaattgga ggaaacagaa tgatgagaag
     7141 cacgaaagaa ttacggcatg tatatagaga cttcctttta gaggctaatc aaagttattc
     7201 tgatatagta gtcttagaag ccgatttgtc aagttcgatg gctactaata atcttgaaaa
     7261 ggattttgga gaccgttatg tgaatgttgg gattatggaa gcagaaatgg tcggccttgc
     7321 agcaggcttg tctattcagg ggtttagacc ttatcttcat acatttggtc cttttgcttc
     7381 acgaagagta tttgatcaat tatttatttc tcttggatac gcacaattgg atgccactgt
     7441 gattggatca gatgcaggag taactgcaga aatgaatggt gggacacata tgccatttga
     7501 agaaattgga ttgttacgtt taattcctaa atcgatcatt tttgaagcaa ctgatgatat
     7561 ccaatttcgt gaaatattga accagacatt agacttaaaa ggactaaaat atattcgaac
     7621 aattagaaaa gctccagttc ctgtgtatca aggtggagaa gatttttcta agggctacat
     7681 tgagttaagg catggtgaag atcttgtaat cgttgcttct ggtataatgg ttgctccaag
     7741 tattcgagtt gcagatgaac tgtctaaatt aggttattca gtaagtgtga tagatttatt
     7801 tagaatcaaa ccgataccag aacagataaa aacaatgtta agtggaaaaa ctatatttac
     7861 tgtagaaaac cacaatcaga taggtggaat tggcagttct ttatgtgaat tattctctga
     7921 tgatggaatg acaaaaattc atcggatggg tgttcaagaa agattcggtc aagtagggaa
     7981 aatggattat cttcttaatg agtatggttt gagtgaatcg aatataaaag agaaggttct
     8041 agaaatttat aatgcaagat agatgttaaa tacacttatc tgaaagaatt tctgtaaaaa
     8101 ttacagtacg ttatttaaag aaagcggatt aaaaagcata ttctggtcat cagaaagtgc
     8161 actaatccgc tttgttgttt ttaattttaa atatttcaca tgtgtataga attttctgaa
     8221 aattcaagat ttttattctg ttcttcatgc gaaaattgtg ctataatagt aaaaactgaa
     8281 atgggaggga taagatgact gaattagata aacgtcaccg cagtagcatt tatgacagca
     8341 tggttaaatc acctaaccgt gctatgcttc gtgcgactgg tatgacagat aaggactttg
     8401 aaacaccgat tgtgggagtg atttcgactt gggcggaaaa tacaccatgt aacattcact
     8461 tgcatgattt cgggaaactg gctaaagaag gtgtcaaatc tgcaggcgct tggcctgtac
     8521 agtttggaac cattaccgta gcagacggga tcgctatggg aacgcctggt atgcgtttct
     8581 ctctaacatc tcgtgacatc atcgcggact ccatcgaggc ggctatgagt ggtcacaacg
     8641 tggatgcctt tgtcgctatc ggtggctgtg acaagaacat gcctggatct atgattgcta
     8701 ttgctaatat ggatatccca gctattttcg cctatggtgg aactattgca ccgggaaatc
     8761 ttgatggtaa agatatcgac ttggtttctg tctttgaagg tatcggaaaa tggaaccacg
     8821 gtgacatgac agctgaggac gtgaaacgtc ttgaatgtaa tgcctgccct ggccctggtg
     8881 gctgtggtgg tatgtatact gctaatacca tggcaactgc tatcgaagtt ctagggatga
     8941 gtttgccagg gtcatcctct cacccagctg aatcagctga taagaaagaa gatatcgaag
     9001 cagcaggacg tgctgttgtt aagatgttgg aacttggtct caaaccatca gatatcttga
     9061 ctcgtgaagc ctttgaagat gctattactg taacgatggc tctcggtggt tctacaaacg
     9121 ccactcttca cttgctcgcc attgcccatg ccgcaaatgt tgacttgtca cttgaggact
     9181 tcaatacgat tcaagaacgt gtgcctcact tggccgactt gaaaccatct ggtcagtatg
     9241 tcttccaaga cctctacgaa gtcggtggtg tccctgcggt tatgaagtac ttgttggcaa
     9301 atggtttcct tcacggagat cgcatcacat gtactggtaa gactgtagct gaaaacttgg
     9361 ctgactttgc agacttgact ccaggccaaa aagttatcat gccacttgaa aatccaaaac
     9421 gtgcggatgg tccgcttatc atcttgaacg ggaaccttgc tcctgacggt gcagttgcca
     9481 aggtatcagg tgttaaagtg cgtcgtcacg ttgggccagc taaggtcttt gactcagaag
     9541 aagatgcgat tcaggccgtt ctgacagatg aaatcgttga tggcgatgta gtcgttgttc
     9601 gttttgttgg acctaaaggt ggtcctggta tgcctgagat gctgtcactt tcttcaatga
     9661 ttgttggtaa aggtcaggga gataaggtgg ccctcttgac ggacggacgt ttctctggtg
     9721 gtacttatgg tctggttgtt ggacatatcg ctcctgaagc tcaggatggt ggaccaattg
     9781 cctatctccg taccggcgat atcgttacgg ttgaccaaga taccaaagaa atttccatgg
     9841 ccgtatccga agaagaactt gaaaaacgca aggcagaaac aaccttgcca ccactttaca
     9901 gccgtggtgt cctcggtaaa tatgcccaca tcgtatcatc tgcttcacgc ggagccgtga
     9961 cagacttctg gaatatggac aagtcaggta aaaaataaac tcatactcga aaatctcttc
    10021 aaatcacgtc aacgtcgcct tgccgtaggt atggttactg acttcgtcag ttctatccac
    10081 aacctcaaaa cagtgttttg ggctgacttc gtcagttcta tccacaacct caaaacagtg
    10141 ttttgagctg acttcgtcag ttctatccat aacttcaaaa cagtgttttg agcaacctgc
    10201 ggctagtttt ctagtttgcc ctttgatttt cattgagtat caaaaagcaa gccattttcg
    10261 gcttgctttt ttcatcttta aaagtgattg gcctgcttaa cgaggtggta gtccaagggc
    10321 aatacggcca tagcgactga ttcgtgtgat tttccaagca ggcgaccagg taacttcaac
    10381 cttgatatct ttgataccct cgatttgttt cagacctgcc acaatttcaa taggcaggct
    10441 ttcggcgcaa tcacaggcag tatcggtgaa ggtcatgaca atcttgcaga gccccgtttc
    10501 atccagattg atttcataaa tcagacctag attgtaaaca tccaattcca catctgtatc
    10561 aaaaactttc tctagttttt cgataatttg gtcttgcaag gccaaagcac ggtcattgat
    10621 tttgatatcg tctctcatag cagtccctcc acgtgataaa tatcctctat tttctcataa
    10681 ttctgacaat ttggcaagtt tttgatgaat tttctgaaaa ataggataaa atgaagaaaa
    10741 tacggaatca aggggaagtc tatggagcag attggaaaag tctttagaca attacgagag
    10801 tcaagaaata tctcactgag acaagcaacc ggaggacaat tttcgccgtc tatgttgtcc
    10861 cgttttgaaa caggtcagag tgagctttcg gtggaaaagt ttctatttgc tctggaaaat
    10921 atatctgcca gtgtggagga gatcctcttt ctggcgagag gtttccagta tgatacagat
    10981 tctgagttga gaaaagaaat tacagatgtc ttggaaccaa agaatatagc acctcttgag
    11041 gacttatatc gcagggagta tcaaaagcat gcccattctc acaacaaaca gaaacatatt
    11101 ctaaatgcca ttattatcaa gtcttatatg aagagcatgg atgaaagggt agagttaaca
    11161 gcagaggaag gaaaagtcct tcatgattat ttgttttcta ccgagatctg gggaatctat
    11221 gaactcaatt tattttcagt cagttctcca tttttatctg tttctctttt tactagatat
    11281 gtacgagaaa tggtacgtaa atctgatttt ctaatggaaa tgtctggcaa tcgaaacctt
    11341 tttcatacta tactattgaa tggcttttta gctagtattg agtgtgaaga atttaccaat
    11401 gcctattatt ttaaacgtgt tatcgaagag catttctaca aggaaaatga gacctatttc
    11461 cgaattgttt atctgtgggc agaaggtctc cttgatagca agcaaggtag agtcaaggaa
    11521 ggccagaaaa agatggagga tgctgtccgt atttttgaga tgcttggctg taataaatct
    11581 gccgaatact atagaaatac gaccgaatgt tgaatatctg caaaccaaga aaaaatttga
    11641 agcgatagaa ctattgccct ctctcaggtc attacaaaag ttctatcgtt tctttttgct
    11701 cattttattt gttgcatata ttcaagagtt ctccctctca aatttctaag tgctatacta
    11761 tagtcatact tcatatagag gttcgaacaa gaagggagat tatctatgaa actattgttt
    11821 agaaatccag cttatagaat tttgatttta tcacgcttct tcaatgcttt tggtgcttcg
    11881 attttcaacc tggtctttat cgtctatgca tcgaccttgt cacaagcatc ttttgctgtt
    11941 gctatggcga atattgtcat gattcttccg accctcttta cagtttttgt agggattcgg
    12001 gcagattaca cgagggacaa ggtcaaatgg atggtctata gcggtttgtt tcaggcggtt
    12061 ctattttttc tagcagccct agttgttcag caagctagtc tctttgcctt ttctagcctg
    12121 tgtttgatca atgtcattag tgatatcatc agtgattttg caggtggcct gcgtatgcct
    12181 cttattaagg aaaaagtagc tgaagatgat ttgatggagg cttattcttt ttcacagttc
    12241 atcacctata tttcagctat tggtggtcaa gctttcggag tctggctctt agctctatcg
    12301 gtcaacaatt tttctctcgt tgcgggaatc aatgcctgct ttttcctagt atcagccact
    12361 atcctctttt taggaaaaag caaattgagc ctgtcaatgt catctgctga tggtgaaaac
    12421 ttaaaaaatg agaagctttc tatcaaagac cagttcctaa caatttaccg aaatttacgt
    12481 ctcgtttttc ttaaaagtgg gcagaaaaac tttggtttta tgctctttgc tgtcttgctt
    12541 attaattcct tgggtggcgc tttgggtgga atttataata tcttcttttt gagccattct
    12601 ctcttgaatt tttcttatac agaggcacta tttatcaatc aattctgtgt tttagtagca
    12661 atcatcatca gtagccttac gggcaatgat tattttggga agcagtcctt gcctagattg
    12721 atgatgtggg cgaccgtagg acttagtcta gttggtttgg ctaatttatt caatcaagtc
    12781 gtgcttggtt tgctatttct cttctttacc ctgtatgtgt ctggtaaagt tcaaccaaag
    12841 attagtgcca tgctcatgaa aaatctagct ccagaggttc tagctcgtac tagtaatttt
    12901 ttaggtctat tgtttacctt atccatacct gtgggaacag cttgtttttc actagtagcc
    12961 gtatggaata tacagttgac ttggatgcta tttgttggtc tttccttgct agctattttt
    13021 ttgacaattc ttaatctcaa aaatgatatc taaatcctaa tttttttctt actgttttaa
    13081 tccctttatt tgtggtaaaa taagactatt aagtttaaag aggattccct atgaaattac
    13141 aaaaaccaaa aggaacgcag gatattttac ctgctgaatc tgctaagtgg cagtacgttg
    13201 agggctttgc ccgtgagatt ttcaagcgct ataactatgc agaagtgcgc acgcctattt
    13261 ttgagcatta cgaggttatc agtcgctctg tcggagatac aacggatatc gtaaccaagg
    13321 aaatgtacga tttttatgac aagggtgacc gtcatattac cctccgtcca gaaggaactg
    13381 cgcccgttgt ccgttcctat gtggaaaata aactcttcgc cccagaagtg caaaagccaa
    13441 gcaagttcta ctatatggga cctatgttcc gttatgagcg tccacaggca gggcgcttgc
    13501 gccaattcca ccaaattggt gttgagtgtt ttggctctag caatccagct accgatgtgg
    13561 aaacaatcgc tatggcagcc cattttttga aggaaatcgg tattcaaggt gtcaaattgc
    13621 acctcaacac tcttggaaat cctgagagcc gtgcagccta ccgccaagcc ttgattgact
    13681 atttgacacc gctcaaggag accttgtcta aggatagcca acgtcgcttg gaggaaaatc
    13741 ctcttcgtgt cttggactct aaggaaaaag aagacaagga ggcagtagag aatgcgccgt
    13801 ctatcttgga ctttcttgat gaagaaagcc aagctcattt tgatgctgtg cgtcagatgt
    13861 tggaaaatct tggagtagat tacatcatcg ataccaatat ggtgcgtggt ctggactact
    13921 acaaccacac cattttcgag tttatcacag agattgaggg caatgacctg accgtctgtg
    13981 cgggtggtcg ttacgatggt ttggtttctt attttggagg ccctgaaact gctggatttg
    14041 gttttggact tggtgtagag cgcctgcttc tcattcttga aaagcaaggt gtgaccctcc
    14101 ctatcgaaaa cgccctagat gtctatatcg cagtcttggg cgaaggggca aatatcaagg
    14161 ccttggaatt ggtacaggct cttcgccaac aaggtttcaa agcagagcgt gattacctca
    14221 accgtaaact aaaagctcag ttcaagtcag ccgatgtctt tgtggctaag accctcatca
    14281 ccctaggaga gagcgaagtc gaaagcggac aagtgacggt caagaacaac caaactcgag
    14341 aagaagtgca agtgtcactt gagacaatca gccaaaactt ctcagaaatc tttgaaaaac
    14401 taggatttta tactcaataa aaatcaaaga gcaaactagg aagctagccg caggttgctc
    14461 aaaacactgt tttgaggttg tggatagaac tgacgaagtc agctcaaaac atggttttga
    14521 ggttgtagat gaaactgacg aagtcagtaa ccatacctac ggcaaggtga agctgacgtg
    14581 gtttgaagag attttcgaag agtattaatg atagataaag tggtcaggaa cttactcctg
    14641 acctttttct tttgcaaaat gacaaaaatc ataaactttt tgacaaatat acttgtcaaa
    14701 aagaaaaaga tatgttacaa tgaattcaag ttaagaaata ggaagcagaa aggagttata
    14761 atgtgggtac taggatttat actatttatg attttctttt attctaataa ttctaaaaaa
    14821 atcaagaaac tagagaataa aatcaaaaaa cttgagcgaa aagagaaagg aaacgcagaa
    14881 atgtcgagat tattacaaga aatgattgga aaggaaccaa ttataacggg agtgtatatt
    14941 gggccagata actgggaagt tgtggatgtt gatgaggaat gggtcaaact acgtagtgtt
    15001 gataatacgg gaaaagaaaa attcaagttg caacgtattg aagatatcca aaccgttgaa
    15061 tttgacggag agtaggtgtg taacgtgcaa ctaaaaaatc gtctaaaaga gcttcgagct
    15121 cgcgatggtc tcaatcaaac cgacctagcc aaactggcag gggtttccag acagaccatt
    15181 agcctactag aacgggatga gtacacccca tccattatca ttgccctgaa aatatctcaa
    15241 attttcaacg aaacagtcga atcggtattt cgtttggagg aggacgagtg atgaacaagt
    15301 ataaagtgat ttattatgta gtggtcatag ctttattagt cagcgtattt ctactgattg
    15361 ggatggacct aagctggttt aatccctatc aaggcgacca atttgtttgg ctctactttg
    15421 ctctcatccc agtaattgaa tggattgaaa agaaatccaa aaatctagca agtgaaaaag
    15481 gagaatgaat atgaaaaaga aacgtagatt gttatttttg atgtctattg tcttgggggg
    15541 gttcttgggc atgtttgtag ggatgtttaa ggcacgtgtc gaatcccacg aaattatttt
    15601 agatgtaaaa gccttgatgc catggatatc agctatttgt ttactgatag gtttcattag
    15661 tatgtttttg actttcaatt tcttaaagaa aagcagaaaa tttcattcct tgtatcaaga
    15721 ggaaatggat gacgatctga atgaaaccta ttatgtgcaa atgtatcgga atcttgagtt
    15781 tggaaccatt gcttttaata ttacaggtgt agcgattcca ttggctattt ttatttcatt
    15841 aagtgaggtg attatattgc atacaaaccc tcaaacattt ttcctttctt tcttactctt
    15901 tgtggtattc ttagtcgctc aaaaatctct ttttaaaacc attgcgattg ttcgtcagtt
    15961 tgatttggaa tttttcgcta caccaaagga tgtcttgaac tatataaatt cttatgatga
    16021 aggggagcgt caggctaatt tggaacagag ttttcgaatt ttattccaat tacaccaata
    16081 tgtcttacca gccttatata tttttcttat tatcatttct ttcttgacag gagagattca
    16141 gttactagct ttcttgcttg taggagccat ccatgtttat atcaatgtga tgcagttacc
    16201 tatggtaaaa cgttatttca aataaaggag ttatctatga aattacttaa aaaccttggc
    16261 tggattcttc tagcccttct atccttttta tttatctatg gctttattca ggggctcgcg
    16321 actgcgtcgc ttgctttagg cgcttcaccc tatgctgtta ctctactcta tgtggccttg
    16381 gctggagtat atgtgtacgg catttacaaa tggtatcaga aggctcctgt tcatattgag
    16441 aagagcggct ttaaccgatt tatttggctt cctgccttgg tttggttctt atctctggtc
    16501 gttcaattct tcttgccaga tgatccttca gtaaatcagc aaatagcgac agacttgacc
    16561 ttgtctcaac cacttttctc attctttgct gtggttattt ttgctccttt gacggaagag
    16621 attgttttta gagggatgtt agcacgctat ctctttccta agcaggacaa tagtaaacga
    16681 accctgattt ttcttctggt atctagtctt ctatttgcct tgattcattt tccaggtgat
    16741 gtgcaacaat tttttgtcta ttttagcctt ggttttagtt tgggcttggc ttacattagc
    16801 agaaaaggtc tggtctacag tatttctctt cacgctttga ataatttagt cggctttttg
    16861 atgattctca tgctataata gagtcaggag gtcacatgaa acgagtaatt ttattagcag
    16921 tgattcaggc agtcgttcta tttttcatca ttggagcgct agcttatgcc ttcaaaggcg
    16981 atttcttcta taactatcta gcagttgtct ttgctcctat tgcaggtgta ctgcgttttg
    17041 ggacggctta cataacggaa attgtcttgc ctcgaaaggc agccgaaatc gctgaaaagc
    17101 gtaaagcagg caaaaattca aaataaaaga gtccggtgaa gttcatcgga tttttgtatt
    17161 atactcaatg aaaatcaaag agtaaactag gaagctagcc gcaggttgct caaaacactg
    17221 ttttgaggtt gtagatgaaa ctgacgaagt cagctcaaaa catggttttg aggttgtaga
    17281 tgaaactgac gaagtcagta accataccta cggtaaggcg acgctgacgt ggtttgaaga
    17341 gattttcgaa gagtattagc gctaattttt agggctttca cttgactttt aaagactggc
    17401 aaacttttct gatgattttc atgaagagcc tgcgctttta tggtaaaata gtaacagaat
    17461 aaaagaggag agaaataatg aaacgtagta tgtatgctgg tcgtgttcgt gaggaacaca
    17521 tcggacaaga aataaccttg aaaggatggg ttggccgtcg tcgtgacctt ggtggtttga
    17581 tctttatcga tcttcgtgac cgtgaaggaa tcatgcagtt ggttatcaac cctgaaaaag
    17641 tatctgcaga ggttatggca acagctgaaa gccttcgtag cgaatttgtt attgaggtga
    17701 ctggtcaggt cgctgcgcgt gagcaagcca atgataagtt gccaactggt gcggttgagt
    17761 taaacgtgac agctcttatt gtgcttaaca cagctaagac aacaccattt gagattaagg
    17821 atggcattga ggcaaatgac gatacacgtt tgcgttaccg ttaccttgac cttcgtcgtc
    17881 cagaaatgtt ggaaaatctt aaacttcgtg ccaaggtgac ccactctatc cgcaactatt
    17941 tggatgagtt ggagtttatc gacgtggaga caccattcct ttctaagtca acgcctgaag
    18001 gggcgcgtga ttatttagtg ccgtctcgtg ttaataaggg gcatttttac gctcttcctc
    18061 aaagtccaca aatcacgaaa cagctcttga tgaatgctgg ttttgaccgt tactaccaaa
    18121 tcgttaaatg tttccgtgac gaggacttgc gtggagaccg ccagcctgaa tttactcagg
    18181 tcgacttgga aacgtccttc cttactgaga aagaaatcca agatattaca gaaggcttga
    18241 tcgcgcgcgt gatgaaggaa acaaaaggca tcgaagtaac gctaccgttc cctcgtatga
    18301 aatacgatga tgctatggct ctttacggtt ctgacaagcc agatactcgt tttgacatgt
    18361 tgcttcagga cttgacagaa gtggtcaaag gtgtagactt taaagtcttt tcagaagcac
    18421 ctgctgtaaa agcgattgtg gtcaaaggag ctgcggacaa ctattcacgt aaagacatcg
    18481 acaagatgac ggaagtagcc aaacagtatg gtgccaaagg tcttgcttgg gtcaaggtgg
    18541 ttgatggaga attaaacgga ccagttgcca agttcttgac tggtatccaa gaagaattga
    18601 caacagcgct tgctcttgaa gataaggact tggttctctt tgtggcggat acgcttgaag
    18661 tggctaatgc aacactgggt gcccttcgtg gacgtattgc taaagagctt ggcttgattg
    18721 ataatgataa gttcaacttc ctttgggtgg ttgactggcc gatgtttgaa tggtctgaag
    18781 aagaaggccg ctacatgagc gcccaccatc cattcacact tccacaggaa gagactgctc
    18841 acgaattaga aggtgatttg gctaaggttc gtgccattgc ttacgatatc gtcttgaacg
    18901 gttatgagct tggtggtggt agccttcgta tcaaccaaaa agaccttcaa gaacgcatgt
    18961 tcaaggctct tggtttctca actgaagaag ccaatgacca gtttggtttc cttcttgaag
    19021 ccatggacta tggtttccca ccacacggtg gtttggctat cgggcttgac cgttttgtca
    19081 tgttgcttgc tggagaagaa aatatccgtg aagtcattgc ctttcctaag aacaacaagg
    19141 caactgaccc aatgacacaa gctccatcaa cagtcgctct caaacaacta gaggaactca
    19201 gcttacaagt agaagaagat gaaacaaaca aaacgaatta agcggtggcg ctattatctg
    19261 cgccgctttg cttatcagat aaaaatttta cgtgtcttac aaagtatctc tcgagaaaag
    19321 tatgatgaga agatttcggc ctctctggtc tatggttttt tatcagcagt agcagttaat
    19381 ttctttttcc aaccagggca tgtgtattcg agtggtgcaa caggtctggc acagattatc
    19441 tctgccttga gtaatcactg gtttggtttt catattccga tttcgctaag cttctacgcc
    19501 attaacttcc ctttgatggt cttagcttgg tatcagattg gccataagtt caccgtcttt
    19561 acctttatca cggtatctat gagttccttc tttatccagt ttgtccctgt ggcaaccttg
    19621 acggaggatc ccattatcaa ttcccttttt gggggtgttg ttatgggttt ggggattggt
    19681 tttgctcttc gaaacaatat ctccagtggt gggacggata tcgtcagcct gactattcgc
    19741 aagaaaacgg gtaagaatgt cggtagtatt tctttcttgg taaatggaac tatcatgctg
    19801 atagcaggtt tgacctttgg ttggaaatac gctctttatt ctatgattac catctttgtc
    19861 tctagccgtg tgacagacgc agtctttact aagcaaaagc gtatgcaggc catgattgtg
    19921 acaaatcatc cagagaaggt aattgaaaaa atccataaaa aattgcaccg cggagcaacc
    19981 atgatccacg atgcagaagg aacctataat cacgagagaa aggcagtttt aatcactgtc
    20041 attacacgtg cagagtttaa tgaatttaaa cagattatga cacaagtgga tccaagctcc
    20101 tttgtctctg tctcggaaaa cgttcatatt ctaggaagat ttgttgagat agataattag
    20161 tgattaatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc cgtatatatg
    20221 ttactgactt cgtcagttct atctgcaacc tcaaaaccat gttttgagct gacttcgtca
    20281 gttctatctg caacctcaaa accatgtttt gagctgactt cgtcagtttc atctacaacc
    20341 tcaaaaccat gttttgagct gacttcgtca gttctatcca caacctcaaa acagtgtttt
    20401 gagcaacctg cggctagctt cctagtttgc actttgattt tcattgagta taaaaagatc
    20461 ttgggaaaag actcaatttc agtagaaaag gaagtaaatc ttcccacaat aaaacgcata
    20521 gtatcaagtt ttttcaatac ctgatagtat gcgtttttgc ttttaacgac tctttgccca
    20581 gtctcttatt tttcgataat tttgtgggcg atcaattgac ggtaacaaat ttgtttattg
    20641 tttttattat cattaataat ctggagaata gtttcaaggg aaacacgacc aagctctaaa
    20701 ctattgatat cgacataggc tgccaagttg agcttgggat taaccgagtc aaagctgaga
    20761 acagggacat ccagctggtg tttggcaata tagttacaaa caccttcagc taggaggcta
    20821 tcggttgtga tgatagcatc aatttgtgga tcgtgcttga ataatcgctt gctaaattta
    20881 tagccctttt cttccagaaa ctcgtcggca aagtagatgc gattgttgtc agtggtaagt
    20941 ttgtaatgtt taagcgcctg ttcatagccc gttaaacggt ctttggtcac gaagagcttt
    21001 ttacttcctc cgataaaggc aatgcgtttg cagccttttt tgatgaaata ttcagtcgca
    21061 tcaaaaccag cttgaacatt gtcgttgtcg acaagtggga tgaaaggaga tagagattta
    21121 cctaagataa ggaaggggaa ctgttcttct gcgacgagtt ttacgagagg gtcttcttct
    21181 tgggcataga gaaagattag cccatctaca cgcttgccgt agaccatttg tgaaatagcg
    21241 ttgagacgct ccttctcatc tttccctgtt gctatttgaa tggcatagtg gttttcagat
    21301 gcgacttgag agatgccacg tagaaccgat ggaaagaaag gattctggta gaaggcgtct
    21361 gagtcatcag gaagaactaa tccgataacc tgagtatagc tgcttaccaa gctacgagcg
    21421 ttaaggtttg ggtggtagtt gagttccttc atagctttgc gaacgcgttt ttttgtttcg
    21481 tcgctaatgg ttgatttatt ttgaataaca cgggttacgg ttgaaggcga aacaccagca
    21541 gccttggcca cgtctttaat cgtaacgggc ataaaaatct cctatttatg gtaatttgga
    21601 tcacggaaat gtgttttata aaagatagtg accagataca gaacaaaaag aatattttgt
    21661 acagtaatca gggttgtcat attttggcca aataatccca aaataagtgt aatcagagtc
    21721 ggcaatccta aacagttcaa gataaagtga tagcactctt taaaggttct aaatgaaaag
    21781 aggcgtgatt tcttagtgat ataaaggaga agactagctc ctagagagac gataaagaaa
    21841 ttcaaaccaa agaggaagct cgcaccgaga actaggaaga ggctgatata gacacgattt
    21901 tgttggtacc agtctttaga aattgcttgg gtcaagctgt ctttgctttt gaaactctca
    21961 gtctgaatgg ctcggtaaga gatgcgggtc agttccttgc tttccttgct gatgactagt
    22021 tcatttgtat cgaaatgcag ttgcaagtcc ttaggtaatt ccttgatttg acctggacca
    22081 atcacaacag aaggggcttg actagctgtt ccagtataag ttaatgtgcc atcgacaatt
    22141 gtagcatgtt cagagagatc ctggacaacc tcatttgtca gaggttcata gacattatcg
    22201 ataaaagttt ctagcggata ggtctcctgg gagctgtttt ggatagcaat gggtaccata
    22261 gacaagctga taaggaagat actggtaaag agaagttgaa accagttgag ctcgaaacgt
    22321 ttggacaggg gcttacgaaa cccccaaata cttgaaaaat aggaaaatgg atatggaagc
    22381 ataggtatct ttctaaaagg tgttttctat atgagtatta ttatatagag aaatgcgctt
    22441 tatttcaagt ctagggggta aattgcttgc tacaaggata ttatttacag tgacaatcgc
    22501 taatagtcaa tgaaaatcaa agtgcaaacc aggaagctag ctgcaggttg ctcaaagcac
    22561 aactttgagg ttggagataa agctgacgtg gcttgaagag attttcgaag agtataaaat
    22621 gaaaaagggt ggcggggata aattatccct tgtcgccacc acttgtaagt cctgaaacaa
    22681 agttcttttg taggaagaag aagagaatac agattggaag ggcgatgagg atagcacctg
    22741 ctgagaagta ggcaatcttc aagtttttcg cattgttaac gaaggtttgg agacctacgg
    22801 caacagtaaa gtattctttc tcacgaagca agaaactaga gaggatgtag tccccgaaag
    22861 gtcccatgaa ggcccagaga gcttgtacgg caaccattgg gcgaacaagt ggtagaacaa
    22921 tttgccagaa gcggcggaag tgtcctgcac cgtctagttt tgcagattcg tctaaagaca
    22981 ttggcactgt atcgaagtag cctttcatga gccaagcatt catcgggata ccaccaccaa
    23041 cgtagaggaa gatgaggaac cagttgtggt taagggcgtt caacataagc gccataacga
    23101 agaaggctgt caaagcggcc atagttggca ccatttggat gatcaagaag aagaccaaac
    23161 tttgtttacg agccaagaag ttgtaacggc tgtaagcata accagcaagt acgatgatac
    23221 ttgtttgaac agccatggta attaaggcga taatcaaagt gttgaggtac caagtaccgt
    23281 acaaggtttc agtgaagagg cctttaaagt tatcaaaatt gaggtcgata ttagtatcta
    23341 gtttaaaggc tgagacgtta cctgctttaa aggctgacat gatggtaatc aacagtggat
    23401 agataattac aattgataga ccaatcaggt aaaggtaagt aaggctttga gtcagtctac
    23461 gtttgagttt aattgagtta ttcatcttag acgtcctcca tatcaaatgc gtgtagtttc
    23521 ttgaatgcga tcatagagat tgagatgaca atgatagaga taatcaaggt aacagctgcc
    23581 gccattgagt attgaggaga tgtacctgtt gtcaaacggt agatccatga gatcaagata
    23641 tcggttgaac cagctccacc tccgacacta ccaggtcctc caccattgaa gaggtacatg
    23701 atagagaagt tgttaaagtt gaaggtgtat tggctaatca aagtaggtgc cgcaacagcc
    23761 aaaatcattg ggaaagtgat gttgcggaat ttttgccaag cgttggcacc gtcaatataa
    23821 gctgcttcgt aaaggtcgtt aggaatagat tgcaagatac ccaaagtcaa aacgtagatg
    23881 tatgggaatc cgagccaacc ttgcatcata atcaaggcaa tcttagtcca agttgggtct
    23941 gttttccaag gaataagagc tccatcaagg aaaggaagga atttagccaa gattggcaat
    24001 acttgagtgt tgatagcacc gacactatcg ttaaacatgt ttgagaatgt caagatagtg
    24061 atgaaggctg ggacagccca aggaagaagg aaaataacac caaagatacg ttttcctttg
    24121 ataaatggtt ggttggcaat gatagctgtg aagataccaa ttacgatttg taaagtagaa
    24181 gctgccaaag cccaaatgat agtccaagaa agaacagaac caaaggcaga acggaaggta
    24241 ctcaagctcc aaatgtttgt aaagttggtc aaaccaaccc agtccaacaa cttgtttggt
    24301 ggcaagtgtt ggaagtcgta gttggtaaag gcgatcatca aggttacgat aactgggaag
    24361 ataatcgcga aggtcatggc aacataagat ggaatgatca agaggtaagg gaagccattt
    24421 tcataaatcc ctttgatcat gtctttgagt gtgcgtggaa ctggaattcc attgttaatg
    24481 cgttttgcaa tcgtatgtgc atctttgata tttgagaaat aaaagagtac ataaacgatt
    24541 acaaagatta gatggaaggc accacgaatc agcataaaga gggaattatc acgacctggt
    24601 ttgtcaccaa gagtgatgag gttgctcaat tcaggggttg caagtgctag gaagtaaagg
    24661 acaaatacga tggttacacc aaggaagata aaacctttgg ctttttgttt attgtaaatc
    24721 tgtcctaacc caggaatgat agacagcagg gctgctttac taggttgttg cttttccata
    24781 ttaactcctt tcataggata ctactttttt ataagaaagc taaattattt gtgtctctat
    24841 tgataaattc aaagggggat ttgatttcca ccccccttga acaaattttt tattcaccaa
    24901 atttttgttt gattgtttct ttgatcaatg ttacagcatc gttagcagct gttttagcat
    24961 ctttttgacc acttacagca tcaaagagca tatttttcgc tggatcccaa actgcagaca
    25021 tttgagagat gtttggcagt ggttgagtgt tcttgaactg tttgataaca gctgttgtca
    25081 actcatcgtt tttaccttca gcgtatgaac gagcctcagt attagctggg atttcgttag
    25141 tcttatcata taatactttt tgttgttcag ttgcaacaag gaagtctaca aatttttgag
    25201 aagcttcaag gttcttaacg gcttgaggaa tgacccaagc tttaccacca ccgaatgcag
    25261 catattcttt tccatttgga agagttggga tagttgcaac tccgtagttt actttagcat
    25321 ctttaaaggc ttgagctttc caaggtccgt cgatgatagc agctgtttta ccttcttgga
    25381 attgagtttg gattaagttt ccagcacctt ctgtatcttg cataccttta ggccattttt
    25441 cgtaccaaga tttagcgtag ttgatacctg cgatagaacc gtcgtttgca agaccgatgt
    25501 ctttagcgtc tttaccgttt tggccaaaga cgtaagcacc gttaccggca agaagtccat
    25561 atgtatagta gaagtttgtc cagtcagcta ggaaggcagt agttttacca tcttcaccag
    25621 cgaatgcgta tttgctatct ttagcaaggt tttccaagtc agcaaatgtt tttggagcat
    25681 ctttcaccaa gtctttgttg tagtacataa caagtgactc gataacggca ggagcaccgt
    25741 aaactttacc attagcagct gttacaagag atttagttgt gtcgtctgtt ttagcaccat
    25801 cgctcaattt cacttctgaa agttgtccgt cagaaccaag gctacctaca cggtcgtatg
    25861 gagccatcat aacatcaggg acattaccag attggttgtc aagagaaagt ttatcaagac
    25921 ctcctagagc atcaccagtt ttaagagtga cttttactcc agcttctttt tcataagctt
    25981 tagcaacctc ttcaatatag ctcttatatc cctcgtctac atatacagtg agttctttga
    26041 cttcagatga accagaatca gcaggcttat cagcagtttt gcttccgcaa gctaccaaaa
    26101 gcaagctagc aagtgtagca gttccaagca ccgcagtgct cttcataaat ttagatgaca
    26161 tagtgtattc ctcccaaaga atagcaagtt ttattgataa ggaaacgcaa acgttttcct
    26221 ttatgagctt agtatagcac aaatagaaaa cggttgcaag tattttttgt aaaaatttta
    26281 aaaaattttt aagcttgatt tgatagcata attttgcatt ttaatagaag aaaagtatga
    26341 aatagataag aatacagtat ttttaataaa aatatatgga atctgtctaa agagggaaat
    26401 caggaggggc tacctccctg tttctaatcc ctatctattt tctatagacg tttgtgcttt
    26461 gttgcatata aattcaagct ccctaaggag gttttgtact ttgtagactg tctcgtgaga
    26521 gtcaaacttt aggattagat agttttaagt tatctttgct aaaatgagtt agtctcctta
    26581 aaaataatca aaaaagtttt ttaaaaacgc ttgcaattat gcttgaaaag gagtatactt
    26641 ataagtaacg caaacgtttg cgtctgcaaa atacgcaacg ttccattatt ttaacacacg
    26701 aggtgctatt atgaaaaaac gtcaaagtgg tgtgttgatg cacatctctt ctcttccagg
    26761 agcttacgga atcggatcat ttggtcaaag tgcttacgac ttcgttgatt tcttggtccg
    26821 tacaaaacaa cgttactggc aaatccttcc attaggagca actagttacg gggattctcc
    26881 ttaccaatct ttctcagcct tcgcaggaaa cactcatttt atcgatttag atatcttggt
    26941 ggagcaaggt ttgttggaag caagtgacct tgaaggagtt gactttggta gcgatgcgtc
    27001 tgaagttgac tatgctaaaa tctactatgc acgtcgtcct cttttagaaa aagcggtgaa
    27061 acgtttcttt gaagtcggag atgttaaaga ttttgagaaa tttgctcaag acaaccaatc
    27121 atggcttgag ctctttgctg agtatatggc tatcaaagag tattttgaca atcttgcttg
    27181 gactgaatgg ccagatgcag atgctcgtgc tcgtaaagct tcagcacttg aaagctatcg
    27241 tgagcaattg gcagacaagt tggtttacca ccgtgtgact caatacttct tcttccaaca
    27301 atggttgaaa ttgaaagctt acgctaacga caaccacatc gaaatcgttg gggacatgcc
    27361 aatctacgta gcggaagatt caagtgatat gtgggcaaat ccacatctct tcaaaacaga
    27421 tgtcaatggt aaggctactt gtatcgcagg atgcccacca gatgagtttt ctgtaactgg
    27481 tcagctttgg ggtaatccaa tctatgactg ggaagcaatg gacaaagacg gctacaaatg
    27541 gtggattgaa cgcttgcgtg aaagcttcaa aatctacgat atcgttcgta tcgaccactt
    27601 ccgtggcttc gaatcttact gggaaatccc tgctggttcc gatacagcag cacctggtga
    27661 gtgggtgaaa ggtccaggct acaagctttt tgcagccgtt aaggaagaac ttggtgagct
    27721 aaacatcatc gcagaagacc ttggcttcat gacagatgaa gtgatcgaat tgcgtgaacg
    27781 tactggcttc ccaggaatga agattcttca atttgccttc aacccagaag acgaaagcat
    27841 tgatagccca cacttggcac ctgctaactc agttatgtac acaggaacac acgataacaa
    27901 tacggttctt ggttggtacc gtaatgagat tgatgatgcg actcgtgagt acatggctcg
    27961 ttacacgaac cgtaaagaat acgaaacagt ggtacacgct atgcttcgta cagtattttc
    28021 atcagttagc tttatggcaa ttgcaactat gcaagattta ctagaattgg atgaggcagc
    28081 tcgtatgaac ttcccatcta cccttggtgg aaactggtct tggcgtatga ctgaagatca
    28141 attgacacca gctgtcgagg aaggtttgct tgacttgaca acaatttatc gccgaattaa
    28201 tgaaaatttg gtagatttaa agaaataaga caataatcag gagacaacta aacatgttat
    28261 cactacaaga atttgtacaa aatcgttaca ataaaaccat tgcagaatgt agcaatgaag
    28321 agctttacct tgctcttctt aactacagca agcttgcaag cagccaaaaa ccagtcaaca
    28381 ctggtaagaa aaaagtttac tacatctcag ctgagttctt gattggtaaa ctcttgtcaa
    28441 acaacttgat taaccttggt ctttacgacg atgttaaaaa agaacttgca gctgcaggta
    28501 aagacttgat cgaagttgaa gaagttgaat tggaaccatc tcttggtaat ggtggtttgg
    28561 gacgtttggc tgcctgcttt atcgactcaa ttgctactct tggtttgaat ggtgacggtg
    28621 ttggtcttaa ctaccacttt ggtcttttcc aacaagttct taaaaacaac caacaagaaa
    28681 caattccaaa tgcatggttg acagagcaaa actggttggt tcgctcaagc cgtagctacc
    28741 aagtaccatt tgcagacttt actttgacat caactcttta cgatattgat gttactggtt
    28801 atgaaacagc gactaaaaac cgcttgcgtt tgtttgactt ggattcagtt gattcttcta
    28861 ttattaaaga tggtatcaac tttgacaaga cagatatcgc tcgcaactta actctcttcc
    28921 tttacccaga tgatagtgac cgtcaaggtg aattgctccg tatcttccaa caatacttca
    28981 tggtttcaaa cggtgcgcaa ttgatcatcg acgaagcaat cgaaaaagga agcaacttgc
    29041 atgaccttgc tgactacgca gttgtccaaa tcaacgatac tcacccatca atggtgattc
    29101 ctgaattgat tcgtcttttg actgcacgtg gtatcgagct tgacgaagca atctcaattg
    29161 ttcgtagcat gactgcctac actaaccaca caatccttgc tgaggcgctt gaaaaatggc
    29221 ctcttgaatt cttgcaagaa gtggttcctc acttggtacc aatcatcgaa gaattggacc
    29281 gtcgtgtgaa ggcagagtac aaagatccag ctgttcaaat catcgatgag agcggacgtg
    29341 ttcacatggc tcacatggat atccactacg gatacagtgt taacggggtt gcagcacttc
    29401 atactgaaat cttgaaaaat tctgagttga aagccttcta cgacctttac ccagaaaagt
    29461 tcaacaacaa aacaaacggt atcactttcc gtcgttggct tatgcatgct aacccaagat
    29521 tgtctcacta cttggatgag attcttggag atggttggca ccatgaagca gatgagcttg
    29581 aaaaactttt gtcttatgaa gacaaagcag ctgtcaaaga aaaattggaa agcatcaagg
    29641 ctcacaacaa acgtaaattg gctcgtcact tgaaagaaca ccaaggtgtg gaaatcaatc
    29701 caaattctat ctttgatatc caaatcaaac gtcttcacga gtacaaacgc caacaaatga
    29761 acgctttgta cgtgatccac aaataccttg acatcaaagc tggtaacatc cctgctcgtc
    29821 caatcacaat cttctttggt ggtaaagcag ctccagccta cacaatcgct caagacatta
    29881 tccatttaat cctttgcatg tcagaagtta ttgctaacga tccagcagta gctccacact
    29941 tgcaagtagt tatggttgaa aactacaacg ttactgcagc aagtttcctt atcccagcat
    30001 gtgatatctc agaacaaatc tcacttgctt ctaaagaagc ttcaggtact ggtaacatga
    30061 aattcatgtt gaacggagct ttgacacttg gtactatgga cggtgctaac gtggaaatcg
    30121 ctgagttggt tggagaagaa aacatctaca tcttcggtga agattcagaa actgttatcg
    30181 acctttacgc aaaagcagct tacaaatcaa gcgaattcta cgctcgtgaa gctatcaaac
    30241 cattggttga cttcatcgtt agtgatgcag ttcttgcagc tggaaacaaa gagcgcttgg
    30301 aacgtcttta caatgaattg atcaacaaag actggttcat gactcttctt gacttggaag
    30361 actacatcaa agtcaaagag caaatgcttg ctgactacga agaccgtgac gcatggttgg
    30421 ataaagtcat cgttaacatt tctaaagcag gattcttctc atctgaccgt acaatcgctc
    30481 agtataacga agacatctgg cacttgaact aatactcttc gaaaatctct tcaaaccacg
    30541 tcagctttat ctgcaacctc aaagcggtgc tttgagcaac ctgcggctag cttcctagtt
    30601 tactctttgg ttttcattga gtataagata caaatttata ctaatacatt ttgtaaaaaa
    30661 gcgagtttcg attgaaattc gcttttttaa atgctgtaga tttgggtcaa tcttgtctaa
    30721 aaatagggaa atcctagata cagtgaagac tttaaatgct ggtttttact gtcctcagcc
    30781 ttatattttt tcgtagttga ttacctcaca cctcttgtat tcgcttacat aaagtattat
    30841 aatataattg taggaaagaa ggtgttttta tgatatacac acttaaattg gtgttgttta
    30901 ttacctttct tgtaataagc ttgttacctg ataagatttt tggaaaaaat aaaaaaattt
    30961 ggaaaatagt ttttgcaata ttgacggcag tggcagcatt gtcatttatg tactaagtta
    31021 ttttaagaat gtagggaaat aaaccctaca ttctttttag ttttttctgt tttctaaatt
    31081 ctatttatcc aagcgcttca acatttcttg cttcttcgct tcaagttctg cacgcttttc
    31141 ttcgatttcg gcatgttttt tctcgagttc agaacaactt gcaccattgc taaattcttt
    31201 tcgccatcag gagatagggt gagtcgacat gtctattact cacccaaagc agtcctacaa
    31261 agcaggaatt ttctgttact tttttggaaa tagtaacgtt tatacagctt tgacacttcg
    31321 tatcaaagcg ccaaacacac tccgagggat ttacagaaag cagaaaagga atgatctggt
    31381 ataagatcat tccttttctc tctttttctt taagtaatta tatacaatgt acgacgaagt
    31441 cgtcattgca atgctgatcc accacctaaa gggaacttta aacaacattg ataagataaa
    31501 gaatataaac aacgaaaata cgttataccc aattaatttt attgtatatc tcatgattaa
    31561 aagttaatcc ttccgttgtt aggaatggca tcatttttat cccataattg tgctaaataa
    31621 gtccccggtg ataataaatt catagcggat tctaaagcaa catcatttac aaaccaacta
    31681 cctagatatc tagaaattgc tgaacgaata gcactttttg ctgcatgttt tccttttact
    31741 ttaattagat ttgcaaggcc tgcagtagtt cctcctaatg ctaaagctat tgtagtatct
    31801 aatagagcac ccatttgatt aactgtaata ccttgccaag ctgctctaaa tggagagtat
    31861 gtaggtggga ttgtataatc gccttgtaat tgtcggttaa ttacttcttt gatccattgt
    31921 tgtgagacgt ctggatgaaa agattggatt tcgtttgcaa gtgtattgat ttgttcttct
    31981 gttagagaag tgacaggttg aagttccata tttgtttcaa tttgcgatac ttgttcagaa
    32041 gcgtatacag ctgaaacact tggaatcgct gatacaatta acacaattga cgtcaaaaaa
    32101 accgaaataa atttcattaa tttgttcatg agcttttctc ctttttattt gtatctgctt
    32161 acattttatt atatactgtt attatagtca agaaaaatat gctattatgt taaaaaaata
    32221 tttttcaaaa tataaatgga cggatttatt ttggatttta tttgttattt tgacctgcct
    32281 ctatattggt aaccatgatt tgtttactct caatcatcaa gaattctctt ttcgtggtag
    32341 cttttggggt ttggtactgg ccttatatca cttattgttc attgataagt ttgtaatttc
    32401 gaatcgaaaa taaagattag aactatgatt gactggctac ttttaatatt gattttggag
    32461 gaagattttg tctctattat ttattatttt aaatttatct attttgtaca atatctattc
    32521 tttgagacgg gagaaatcga aatacttgat ttatacggcc tatatcatat ttggggtaaa
    32581 tgtagtatat ggtattcaat ggttattaag agaactgatt tcaactattt ccccttaatg
    32641 tgtatggaaa ctataacaaa acgcataaga ttaaggtttg tgtacctgtt cttatgcgtt
    32701 tttgtaatat tgaagatttt cggtaagttt tatacctttg ggaagtctag tttagaatgc
    32761 tttcccaacc agaatctctg cttcgatggt aatctctgtc agttggctcc agtcaatctt
    32821 gctctggtca acatgaaaga ggagaggagt catactgagt agggcttgga gttgttctgc
    32881 tgtgatagtc ttagtcagag aggcagtttg actagatagg atggtaaagt gttcctggaa
    32941 atgctccttg atatcttggt tagaatactc cttgtttgtc agctggtcct gtactctttg
    33001 acggatttct ttgaggtgat tttcagttgg gataaccttt atcaagatac cgtctttgga
    33061 taaaacgcga cgaaattctc catagttggc aggtgagaag atatcaagca gaatatccat
    33121 gttagcgtct tttataggaa gtcgtgccaa gtcgccaacg aaccaattga ctgcccagtt
    33181 gggttcactt ttagcagcga tttggactga atctttggag atgtcaaagg catagaaagt
    33241 tttttcagag tgactttctt gtagtttgcg agaatagaat ccttcaccac aaccgatatc
    33301 caaaattgtt gtggtagttt ttgagcttgc aagcaagtca gatacagcat ctaagatagc
    33361 ttggtaaaag ccggcttcta ggatttgttg acggttttga aaattttcct tgtcatagtt
    33421 agcagattgc ttgatttgag gtgctagatt gacatagcca aatttcgcca agtcaaaaga
    33481 atgacggttg cagcacttga aattagtctc taacagagtc agattttctt gacagatagg
    33541 acaggcaaag gcagtcgcag aagcaaaacg ctgaagtttg ggcttgagat ttgtattcat
    33601 agtttaagtg tatcaaaaga ggcaaatgaa agcaacttta ggaataagta gatgggagat
    33661 tcagtagaaa taaaactaat tctccaattt atagaatgaa attgctttta tatctaaatt
    33721 gctatataat aatgataagg aggaaataag tatgttaaaa gaagtattaa ccgttgcaaa
    33781 agttgcgaaa aaatcttcat tatttttggg tggtgtcgca tttggtaccc ttggtttgaa
    33841 aatcttagca agtaaggaag ctaaaaaagg ttattctaaa gctttggcta aggcttacaa
    33901 gttgaaagac gagctagatg catctgtttc tgttgtgaag caacatggag acgatgtctt
    33961 gcaagatgcc aaatatttgt acgagcaaga gaaaaaagaa gagcaattag atagccttat
    34021 aggtgaataa tatgtctttt aaagtgctac atagaggata ccaacatatc cgactatcat
    34081 cttctttttc acttaccttg gatattcaag actatcttcg ttccttggcg agagatgaaa
    34141 aggggattga gtctatccag ttttacatgg atcaacagca ctttactcta cgcataaaag
    34201 aaggcttttc tgtattagat aatgcagaag cctttttaaa aagaattgat aaagggaaag
    34261 tttctgagtt gatgactctt cccattcgta gagaagagag tgcttattct attgtttcag
    34321 gtgcagcggt taagcgtgta ctttttcgta gttttgtgcc gtatcctatt cgctatatat
    34381 ggacttgtta tcaggctttg ggttatatta gagaagccta tcaaacacta gcgcgtaagg
    34441 aactaacgat ggaagtcttg gactgttcgg ctattttatt gtctttgttt atgaaccaat
    34501 ccaagacagc tagcaatatc atgtttatgc ttgatttggg gaatcattta gatcagtggt
    34561 ccttgaaaaa aactgcaaca gatttagaac agagtcttct tgcaaaagag agcgatgtat
    34621 tcctagtaca gggcgatacg gttgttagta tcaagagttc cgatgttcaa ataggagatg
    34681 tcttgatctt atctcaagga aatgaaattc tgtttgatgg acaagtagtt tcaggtttag
    34741 gtatggtcaa cgaaagttcc ttgacaggag agagttttcc agttgaaaaa agagagtctg
    34801 atttggtttg tgcaaataca gtattagaaa ctggagagtt acgcattcgt gtaacagata
    34861 atcagatgaa cagccgtatt ttacagctga ttaagttgat gaagaaatct gaagaaaaca
    34921 agaaaacgaa acaacgctat ttcatcaaga tggcggataa agtcgttaaa tataatttct
    34981 tgggggctgg gctgacttac ctattgacag gttctttttc taaggctatt tctttcctat
    35041 tggtcgattt ctcctgcgct ttgaaaatct ctactcctgt agcttatttg acagttatca
    35101 aggaagggtt gaaccgtgaa atggtgatta aggatggaga tgttctggag aaatatctgg
    35161 aagttgatac tttcttgttt gataagacag gaacaatcac aactagttat cctatagttg
    35221 aaaaggtgtt accttttgga gactatagtg aggaagatat tctcagaatc agtgcctgtc
    35281 ttgaggaaca catttatcat cctattgcta atgccatcgt caagcaagct gagatagagg
    35341 gaattgaaca tgaggaaatg catgggaaac tccaatatat cgcaagcaag gggatcaaat
    35401 ctcatataga tggccaacca gttcttattg ggaattatgt cttgatgcag gatgagcaga
    35461 ttcatatcag ttcagaacaa aatgctttaa ttgaagagta caagagtcac tacaatctct
    35521 tattcttggc ttatcaaaat gaattgattg gaatgttctg cattcatact cctttgagaa
    35581 aagaagcaaa aacagccttg gataaactta aggcacaggg gaaaaaattg attctggcaa
    35641 caggagacac cttgattagg acagaggaat tagtcaaaga tttgcccttt gatcaggtct
    35701 atacagactt gaaacctgat gggaaatttg agttagtaga gaaactgcag aaagcaggtc
    35761 acactatttt gatggttgga gatggattga atgactcagc ggctttaact ctatcagata
    35821 tcggtgtggt gatgaatgag agtgcagata tttctaagca gatgagtgat atcttattgt
    35881 tagataatcg tttggatttc ttccaagagt tggattcgtt atcatcatct ttgcaaacac
    35941 tcatcaagaa aaatattcaa gataccgttg tcgtaaatag tagtttgatt ggctttggct
    36001 tatttaattg gctcagtcct tcaaatctct ctatcttaca taatctaaca accttgcgca
    36061 ttgtcctgcg tagcctgtct attaaaaata gatagatgag agttattaac agcaaaaagg
    36121 agttaccttt ctcgaggtta actcctttgt ttatagataa atgttgaatg gtttagtaag
    36181 tcaatacaaa gtattttttc ttcccacgac ggataacagt cagttcattt tctaacttat
    36241 cagcgtcact caagacatag tcaaggtctt ggatgcggtc gccgtttacg tagatggctc
    36301 cgttttggac gtcttcacgg gcttggcgtt ttgagttaac tataccagat gagacgagca
    36361 gttccacgat attgttgttt tcgtctgcct gtacttggta gtttggcaca ccacgaagtc
    36421 cttgtttgag ctctttgaca gaaaggtttt tgatgtttcc tgcaaagagt tgctcagtga
    36481 tgttaagtgc ttctttgtag gcttcttctc cgtgaacaag tgtaacaact tcacgagcca
    36541 agactttttg agccaagcgt tcgtgtggcg ctgcttcaaa ttgtttacga atatcttcaa
    36601 tctcatcaag tgacaagaaa gtaaagattt tcaagaagcg aacagcgtca gcgtccatca
    36661 cgttcatcca gaattggtac atttcgtatg gagaagtctt ttcgggattg agccagacgg
    36721 catttccttc tgatttacca aattttttac cagttgcatc tgtgattagt ggaacagtga
    36781 taacgtgacc agtcttgtcc gccttacgac gaagcaattc ggtaccagct gtcatatttc
    36841 cccactggtc agaaccaccg atttgaagag tgacattatg gtcttggtta aggacgaaga
    36901 agtcgtaccc ttgcatgatt tggtaagcga actcagtgta agaaattcct gtttcgatcc
    36961 gttttttaac agattcctta ctcatcatgt agttgaccgt gaagtatttt ccaatgtcac
    37021 ggaggaagtc aatgaagctg atgctgccaa accagtcgta gttgttgacc atgacagcct
    37081 tgttttcgcc attttcaaag tcaagaaaac gagaaagttg tccttggata gacttgaccc
    37141 agccatctac tgtgtctttt gtttggagac tacgttcagc atctttgaag gacggatctc
    37201 cgatgagacc tgtagcaccg ccaacgagcg cataaggttt gtgacctgct agttgcaagc
    37261 gacgacttgt caagattgcg acaaggtggc ctaggtgaag gctgtcagca gttggatcgt
    37321 agccagtata ataagaaact tgaccttctt ctagggcttt acgcaaagct tcttcatcag
    37381 tcgtttgaaa tatcaaacca cgctctttta gctcatcaaa aatgtgcatg tgtcttttct
    37441 cctttttaaa attattgttt ctacctattg tatcacaaac ttgggcaata gcctagcaga
    37501 atagggaaga aagtggctat tttattgaaa atttcccttt tgtggtataa tagatagagt
    37561 gaggaaatcc atgcaaaatc aattaaatga attaaaacga aaaatgctgg aatttttcca
    37621 gcaaaaacaa aaaaataaaa aatcagctag acctggcaag aaaggttcaa gtaccaaaaa
    37681 atctaaaacc ttagataagt cagccatttt cccagctatt ttactgagta taaaagcctt
    37741 atttaactta ctctttgtac tcggttttct aggaggaatg ttgggagttg ggattgcttt
    37801 ggggtacgga gtggccttat ttgacaaggt tcgggtgcct cagacagaag aattggtgaa
    37861 tcaggtcaag gacatctctt ctatttcaga gattacctat tcggacggga cggtgattgc
    37921 ttccatagag agtgatttgt tgcgcacttc tatctcatct gagcaaattt cggaaaatct
    37981 gaagaaggct atcattgcga cagaagatga acactttaaa gaacataagg gtgtagtacc
    38041 caaggcggtg attcgtgcga ccttggggaa atttgtaggt ttgggttcct ctagtggggg
    38101 ttcaaccttg acccagcaac taattaaaca gcaggttgtt ggggatgcgc cgaccttggc
    38161 tcgtaaggcg gcagagattg tggatgctct tgccttggaa cgcgccatga ataaagatga
    38221 gattttaacg acctatctca atgtggctcc ctttggccga aataataagg gacagaatat
    38281 tgcaggggct cggcaagcag ctgagggaat tttcggtgta gatgccagtc agttgactgt
    38341 tcctcaagca gcatttttag caggactccc acagagtccc attacttact ctccttatga
    38401 aaatactggg gagttgaaga gtgatgaaga cctagaaatt ggcttaagac gggctaaggc
    38461 agttctttac agtatgtatc gtacaggtgc attaagcaaa gacgagtatt ctcagtacaa
    38521 ggattatgac cttaaacagg actttttacc atcgggcacg gttacaggaa tttcacgaga
    38581 ctatttatac tttacaactt tggcagaagc tcaagaacgt atgtatgact atctagctca
    38641 gagagacaat gtctccgcta aggagttgaa aaatgaggca actcagaagt tttatcgaga
    38701 tttggcagcc aaggaaattg aaaatggtgg ttataagatt actactacca tagatcagaa
    38761 aattcattct gccatgcaaa gtgcggttgc tgattatggc tatcttttag acgatggaac
    38821 aggtcgtgta gaagtaggga atgtcttgat ggacaaccaa acaggtgcta ttctaggctt
    38881 tgtaggtggt cgtaattatc aagaaaatca aaataatcat gcctttgata ccaaacgttc
    38941 gccagcttct actaccaagc ccttgctggc ctacggtatt gctattgacc agggcttgat
    39001 gggaagtgaa acgattctat ctaactatcc aacaaacttt gctaatggca atccgattat
    39061 gtatgctaat agcaagggaa caggaatgat gaccttggga gaagctctga actattcatg
    39121 gaatatccct gcttactgga cctatcgtat gctccgtgaa aagggtgttg atgtcaaggg
    39181 ttatatggaa aagatgggtt acgagattcc tgagtacggt attgagagct tgccaatggg
    39241 tggtggtatt gaagtcacag ttgcccagca taccaatggc tatcagacct tagctaataa
    39301 tggagtttat catcagaagc atgtgatttc aaagattgaa gcagcagatg gtagagtggt
    39361 gtatgagtat caggataaac cggttcaagt ctattcaaaa gctactgcga cgattatgca
    39421 gggattgcta cgagaagttc tatcctctcg tgtgacaaca accttcaagt ctaacctgac
    39481 ttctttaaat cctactctgg ctaatgcaga ttggattggg aagactggta caaccaacca
    39541 agacgaaaat atgtggctca tgctttcgac acctagatta accctaggtg gctggattgg
    39601 gcatgatgat aatcattcat tgtcacgtag agcaggttat tctaataact ctaattacat
    39661 ggctcatctg gtaaatgcga ttcagcaagc ttccccaagc atttggggga acgagcgctt
    39721 tgctttagat cctagtgtag tgaaatcgga agtcttgaaa tcaacaggtc aaaaaccagg
    39781 gaaggtttct gttgaaggaa aagaagtaga ggtcacaggt tcgactgtta ccagctattg
    39841 ggctaataag tcaggagcgc cagcgacaag ttatcgcttt gctattggcg gaagtgatgc
    39901 ggattatcag aatgcttggt ctagtattgt ggggagtcta ccaactccat ccagctccag
    39961 cagttcaagt agtagttcta gcgatagcag taactcaagt actacacgac cttcttcttc
    40021 aagggcgaga cgataattct ctaaatgaag tggccaatca atggattgcc acttttttcc
    40081 tttcgtgtta caataagggt atgaatcagt atcagaaaaa gattgttaac ggaaaaattt
    40141 attcgctcct atccggctta atatggggaa tctgtggaat tttaggagag tacttcttta
    40201 ctcattatca ggtgtcttcg ggctggatta cctctatgcg tttgacactg gcagggagtc
    40261 ttgtactcat ttggtctgca atacaattaa aatcgcaagt gctagatatt tggcgagaca
    40321 agaaaaatta cctgcccttt ttagcctatg ctattttggg gattttttca gttcagtatt
    40381 ttttctatct ctgtgtagaa tactcaaatg ctacgacagc aactatttta cagtttatta
    40441 gccctgtttt tatcctcttt tacaatcgct tggtttatca aaaacgagcg tcaaaaagcg
    40501 ctgttttcta tgttttggtt gccatgctgg gtgtttgctt gatggcgaca aagggagatc
    40561 tctctcagtt atccatgacg ccgctagctc ttataacagg tttgctgagt gccatgggtg
    40621 ttatgtttaa tgttatcttg ccccaacctt ttgctaagcg ttatggtttt gttcctacgg
    40681 ttgggtgggg gatgattttg gcaggtttgt ttagcaatgt cctctcgccg gtttatcagc
    40741 tttcctttac tcttgatatt tggagtatct tgatttgcct cattatcgct ttctttggaa
    40801 cggcttttgc ttttttcatt tccatgaagg ctgtgtcctt ggtttctcct ttggtggttg
    40861 ccgttatcag tgccagtgaa cctctctctt ctgctctctt gagtgttttg ttcttaggat
    40921 tagtagtgga ttggtccctc cttctagcta tagccttgat tattttaccc atgatatttt
    40981 tgtctataga agaagcgaaa gaaagtagat aaaaagtctt ttcttaattc taaaagtgtg
    41041 ctatactaga atagtcaata aaacacgggg agatagttgt gaagagtgtt tttaggttgt
    41101 atcggtaggg gcttgctttt accgacagca cgttttatct cacatcccta aaaaatcata
    41161 cctaaaaaca gacaaaaagg tttcaaattt gaggcctttt ttggtagaat aggtatcatt
    41221 ataacgaacc aggaggcacc tatgactgct acaaaaatga acgctcaaga aattatccaa
    41281 tttatcgcca atgctgaaaa gaaaaccagt gtcaaagtaa cctttgaggg gcaactcgca
    41341 actgctgtgc ctagctctgt tgtcaaacta ggaaatgtcc tattcggaga ctggaaggac
    41401 gtggctccgc ttcttgaagg tttggtagaa aatcaagatt atgttgtcga gcaagatgct
    41461 cgtaattctg cagttccttt gctagataag cgtgctatca acgctcgtat cgagccaggt
    41521 gctattatcc gtgaccaggt ggaaattggt gacaatgctg ttatcatgat gggagctgtt
    41581 atcaatatcg gtgctgaaat cggtgctgga accatgattg acatgggtgc catccttggt
    41641 ggccgtgcta tcgttggaaa aaatagccac gttggtgcag gtgcagtttt ggcaggtgtg
    41701 attgagccag ctagtgctga accagtccgt gtcggagaca atgttcttat cggtgctaat
    41761 gcagtggtta tcgaaggagt ccaaatcggt agtggttcag ttgtcgctgc aggagctatc
    41821 gttacccaag atgtcccaga aaacgtggta gtagcaggtg ttccagctcg tatcatcaaa
    41881 gaaattgatg cccaaaccca acaaaaaaca gcgctagagg atgcgcttcg taccttgtaa
    41941 ttgtaaaagt aaaaaagagg cggaaccctt tttccagcct ctttctgcta taacggagga
    42001 cagatagatg ttagatttga ttcagactag acgagcttta caccagattc cagagattgg
    42061 cttggaggag ttcaagactc aggcttattt gctggatgtg attgagaaat tgactacggg
    42121 caaggatttt gttcaaattc gtacttggcg gacagggatt ttggtctacc tgcagggaag
    42181 tcagccggag cgaaccattg gttggcggac agatattgat ggtctgccta tcgtcgaaca
    42241 aacaggtcta ccttttgctt ctcaacacca aggtcgcatg catgcctgtg gccatgattt
    42301 tcatatgacc attgccttag gctgtcttga gcgcgccctt gaggagcaac ccaagaataa
    42361 tctgctcttt ctatttcagc ctgctgaaga aaatgaagct ggtggcatgc tcatgtatga
    42421 ggacggtgct tttggagatt ggttgccaaa ccaattctat ggtctccatg ttcgtccaga
    42481 tttgaaagtc ggccagattg cgactaatac tcatacactc tttgcaggaa cttgcgaggt
    42541 gaagatccgt ttcaaaggca aaggtggcca cgcagctttt cctcatgaag ccaatgacgc
    42601 cttggtggcg gctagttact ttgtgaccca agtgcagtca gttgttagcc gcaatgtcaa
    42661 cccaatcgag ggagcagtgg tgaccttcgg cgtttttcaa gctggaacca ccaacaatgt
    42721 catcacagac acagcttttt tacatggaac tattcgtgcc ttgacacagg acatgagtct
    42781 cttggtgcaa aagagggtaa aaacagttgc agaaggggtt gcagctgcct ttgatatgga
    42841 agtcgaagtg gaactcaaac aaggtggata cctacctgtt gagaacaatc cagccttggc
    42901 gcgtgaactg atggacttct ttgacgaaaa agacggaatc gagttgattg atatcgaacc
    42961 tgctatgaca ggcgaggact ttggttatct cctttcaaag gttgatggcg tgatgttttg
    43021 gctaggtatc gatagtccct acgctcttca tcaccctcaa atgagtccta aggaagaagt
    43081 cttagctatt ggggtggctg cggtgtctag tttcctgaaa aagaaggcag cagaatagag
    43141 ggcttgtcta tgaaatcgga attacgcaag caagtcttgc atgaaatgaa ggctatatct
    43201 caagagcaaa aacaggctat agaccaagct ttaaccgagc ggcttttaca ccatcccttc
    43261 taccaagaag ccaaggtcat cgcaacctac ctctcttttt ctcatgagtt tcaaacgcgg
    43321 gaactgattg agcaggcgct gaaggacggc aagaaggttt taatacccaa aacttatccc
    43381 aaggggcgca tggagtttgt ggtctatgat ccgcaacagt tggtaaaaac ttcctttgcc
    43441 ttactggagc cacagggaga tgtggaagtg gtggatgcat ctcagattga tttgattcat
    43501 gttcctggtc tggcttttac gacgaaagga tatcggatag gatacggtgg aggctattat
    43561 gaccgctatc tggaacattt ttctggtcgt actttgagta cgatatatcc ttgtcaaatt
    43621 caggacttta tacctgaaaa ccatgatatt cctgttcagg aggtattaat tgatgaagga
    43681 aatctttgat agacgttacc ctgtgacgag tttcttcctc ttagtgacgg ccttggtatt
    43741 tttactaatg ttggtcactg caggcggaaa ctttgacagg gcagatacat tatttcgatt
    43801 tggagccatg tatgggccag ctattcgcct ctttcccgag caggtttggc gtctcttgtc
    43861 tgccattttt gttcatattg ggtgggaaca tttcattgtt aatatgcttt cactttatta
    43921 tcttggaagg caggtagagg agattttcgg ttctaagcag tttttctttc tctatctttt
    43981 atcaggaatg atgggcaatc tctttgtttt tgtatttagt cctaaatcct tagcagcagg
    44041 cgcttctacc tctctttatg ggctatttgc cgcgattatt gttcttcgct atgcaactcg
    44101 caatccttat attcaacagc tagggcaatc ctatctgaca ctttttgtgg ttaacattat
    44161 tggaagtgtt ctgattccag gaatcagcct agcaggccat atcggtggtg cagttggtgg
    44221 cgcatttcta gcagttatct ttccagttag aggagaaaaa cggatgtata ataccagcca
    44281 gagattagga gcggtagtct tgttcgtagg actcgccatt ttgcttttct acaagggaat
    44341 gggaatgtga cgaagttgaa agaaaatttg tgtaatgaaa aaagataagg cattttttga
    44401 accttatctt tttattttat tttattcctt ctcagtcaat tcttttccaa gttggatgag
    44461 gtaattcttc aaatcatctt tgacttgtgg gtgtttgagg gcgtagtcga tggatgtttt
    44521 catgaagcca aacttgtctc cgacatcgta acgagcccca ttgaactcac gagcaaatac
    44581 acgttgtgtt ttattgaggg tgtcgattgc atctgtcagc tgaatttcat ttcctgcacc
    44641 tggagcttgg ttttcgagga tttggaaaat ttcaggcgtg aggaggtagc gtccgataat
    44701 agcaaggtcg ctaggagcgt cctctggagc tggtttttca acaaaggttt caacactgta
    44761 aagaccatct tttccttcgc cttgcggagc aataaccccg taagcagata cttcgtcatg
    44821 agggactggc atgacagcga tagtagacgc gtgggtacgc tcgtagtcat ccatgagttg
    44881 tttggtaagt ggaacagcct tttcgtctgt gatatccatc aagtcatcac caagcataac
    44941 gacaaaaggt tcatttccga cgaaagcctt agcttgcaaa acagcatctc cgagaccgcg
    45001 tggatgagtt tggcggataa aatgcagacg catgtcagtt gttttatcaa ctagcttcaa
    45061 aagatctgtt ttcccttttt ctttgaggtt atattccaat tcgaagtttg aatcaaagtg
    45121 gtcctcaata gaacgttttg atttaccagt gacaactaga atatcttcaa tacctgattt
    45181 gagagcttct tccacgataa actggatagt tggtttgtct acgattggca acatttcttt
    45241 ggcaagggcc ttggttgctg gtaaaaatcg agttcctagt ccagcagcag ggatgactgc
    45301 ctttctaact tttgatgtca taaaaatcct ttctatagag ggttaagacc actcattttc
    45361 tgctttaaat tcattgttca tgatgtcata aatggcatct ttgatattgg ttccgtgata
    45421 aataacttgg taaatagcct gtgtaatggg catatagact ccaagttctt gggctagttc
    45481 ataggctgct cgagtcgttg aaattccttc gattaccatg cccatattag cttctatatc
    45541 agctagggat tctcctcgtc cgagagcatc tccagctctc cagttacgag agtggatgga
    45601 agttcccgtt acgatcaaat ctcccacacc agataagccg ctataggtca atggactggc
    45661 cccgagtgct acccctaggc gggtgatttc tgctaaacct cgagcgatga tggctgcctt
    45721 agcattatca ccaaatccaa gaccatgtaa agctccagca ccgacagcaa taatattttt
    45781 aagagcacca gcagtttcaa ccccgataac atccgtattg gtataaagtc ggaagtagtg
    45841 attactaaat agcttctgaa cgtattgagc tgtttgtaaa tctttagaag cagcagttat
    45901 taaagttagg tcacgcacaa tggtctcttc tgcatgacta ggccctgaaa caacgacgat
    45961 atcactacgg agatgttcag gaatttcttc ttcaagaatg gttgataatc gtttatggct
    46021 atcaggttct aatccctttg atgcgtgcat gatgataacc ttatggtcca aggtttgtgc
    46081 aacttgctgg gcaacaagtc gtgtcacttt tgttgggaca acaaacaaaa tcgcatccac
    46141 atctttcaat gtttctgcta agtcggtgta ggcaatgata ttttcgtcta gaacgacatc
    46201 tttaaagtag tgcttattag tatggtgtgt attaatttca ttgatttgct cgggaagatt
    46261 tccccaaata cgtacctcgt gtccattgtc atttaagact tgtgaaaggg cggttcccca
    46321 agaaccaggc cccaagacgg cgacggtttg tttttccatg atttcctcct tgatagagtt
    46381 ctttctctta ttctatcata ttctagggga ttttgcactt gcattactgg ggtatggtgg
    46441 aaaaatacac aaaaaccgag acgaagggat aaactcttag tctttagtta aagtgagaag
    46501 aaatctgata gatagtttga ttcagtatat gcttataata gaggtaaaca actcaggaag
    46561 ttcttgtagg ttgcgagagt ttggctaaaa aaatcagtcg ttcagaattt tgtggtgatg
    46621 agtctgaatt aagtatccgt caattaatta gaattgaaaa tggagaatcc agaccaacac
    46681 taacaaagtt aaaatatatc gctgaacgtt tgggggttga agattacaag ttgatgccaa
    46741 gttatataga gttggataag gaatacctag aattgaagta tttcttgatg aggactccta
    46801 catacgaaga tgaaactatc gcccaaaaga aagagagtgt tttgataaga tttttgaaga
    46861 gtattatgat aggctacctg aggaagaaag atttatcatc ccaaattatt catatctggc
    46921 actaacgaac tacacagttc aaaaattacc agaaaagcta gttgaaatac tgtccttctg
    46981 gtgattttgc ttaatttctg atgttcgaga cataattgag gagatttgtc ttgatttttt
    47041 cctaaaaaag ggcagactcc tcccttggtt tgatgctcga tttttaaaat aaggtgactt
    47101 attctgttag gcatgttttc ccctgccctc tagctctata tggaacaggg agtatcagat
    47161 ttatctggca gattgtatca aataaggctt gaaactgttt tgaataggca tatagacttg
    47221 agaatttgag aatatgtcgt ctagcagtag agacatattt tccggcaata tgaaggaaga
    47281 gacgtcgaaa acgcttgata gtcaaggcct ttacttcatc accagctagc tgctttaaaa
    47341 agaggtagag attataagcc agacagccca tcatcatacg tacttcattc ttaatcatgg
    47401 tcgaactatc tgtcttatcc ccaaagaatc ctgctttcct ttctttgata aagttttcag
    47461 cattccctcg ttcacgatag aattgaaaca gctcctcact atctacactg cttaaattgt
    47521 tcaaatgaac ttttttacaa ccataaaaaa gagcacttaa tcgtactctt ctcttttaag
    47581 gattagttga attaattcaa atccaccagt tctcctgttt ctaggtagac taggcgttca
    47641 caaatgttag caatgtaatc agcgaagcgt tccagatgcc ctatgatata aaggtattga
    47701 gttccattgg gaattgaggt ttcttggtct ttcataagtc caatgatttc ctttgataag
    47761 gcataataat attggtcaat ctgttcatct ttttgagcaa tactaatagc ttttgaggct
    47821 tggtgcaaag gaaaggcaac caataaatcg gctagcatgc tgagggataa tttacccatt
    47881 tggtgtaact gttcttcgtc aggggctagt tgattttctt ttagttgcaa aacagcttta
    47941 gcaatgcctg ccatatggtc tcccatacgt tcaaggtctg aacaagaaga catgatgcta
    48001 atcacaaatc gaaggtcaga cacttgtggc tgctgcaagg ccaacaaacg ggcacaggtc
    48061 aattcgatag cgctttgacc ttggttgata gcatgatcct tattgataat tagctctgcc
    48121 atctccttgt ctttggaggc taaggccagt aaggcttttg aagctgtttc aaggacaagt
    48181 tgccctagtc ctaaaaagga ttgttctaat tcatgcaatt ctaagtcaaa ttgatttctc
    48241 ataggttttt ccttccttat ccgaaccgtc ctgaaatata gtcttctgtg cgctgatctt
    48301 ttggattggt aaacacgtca acggtatctc caaattcgca aatttctcct gttaagaaaa
    48361 aagcagtttt atctgaaata cgtgaagctt gttgcatgtt atgggtaaca atgataatcg
    48421 tataatcctt ttttagttgc tgaatgaggt cttcaatttt taaagtggag atagggtcta
    48481 aggctgaagt cggctcatcc attaacagaa tatcaggttc tactgctaaa gctcgcgcaa
    48541 tgcaaaggcg ttgctgctga ccgccagata aggacatggc actcttttta agatcatctt
    48601 tgacttcttc ccaaatggct gcccctttta aagatttctc cactaaggca tctaattgtt
    48661 ttttgtctcg aataccatgt gtccttgggc cataagccac gttatcatag atagacatgg
    48721 caaagggatt aggctgttga aaaaccatcc ctacacgctt acgtagctga ttaaggttga
    48781 atttgctact ataaatatct tgctcatcta agaggacttg gccttcaata tggcaagaag
    48841 gaaccaaatc gttcatccgg ttaagggttt ttagaaaagt tgatttgcca caaccagatg
    48901 ggcctatcaa ggcagtaatc tgtctttctg gtaattgaat cgaaatattt tttaaggctt
    48961 gaaaatcccc gtaaaataag tctaggtgtc tgactgaaaa tgttcccata ctaggaagct
    49021 cctttcacaa gttttcgaga taataagctt gatagagtat ttatcattaa aacagtaata
    49081 atcaaaatca caccggtagc ataggcttca ttgacatgta gcccctcact tgacagcata
    49141 tacatatgca gggctagaga acgacctgaa gacatgagac tacttggcgt attggtagag
    49201 gtacctaatg tatacatgag ggcagctgtt tcaccaacga tacggccaat agctagtatc
    49261 actccagcta aaatacctgg catggcaact ggtagaacaa ttctaaaaac agtccgtaac
    49321 ttacctgccc caagtccata acttgcttga cgcatgctat cactaacaga taaaagggct
    49381 tcttctgttg agcgaataat gactggcaac accatgataa ctgaggttaa gattcctgat
    49441 aacagagagt attgaaaacc taagaagact acaaagaaga gcatgccaaa cagaccaaaa
    49501 acaatggaag gaatcccaga caaggtatct gaggccaatc gcatgatttt aacacaaagg
    49561 gaatcttttt ttgtatattc cacaagataa aaaccagcaa aaatccctat gggcaaggct
    49621 aaaagaagag caccaaagac cagaataacg gtggaaataa tcgctggcat aagggaaatg
    49681 ttctcagaag tataagtcca agaaaagagg gatagactta gatgaggtaa gcctttgatg
    49741 aggataaaac caatgattaa aaagagagag ccaaaggtta aagctgaaaa acaataaacg
    49801 agaagtttta gcaggtattt actcataaga tgattttcct ttcaagtagg caaagtaggc
    49861 attaatcaag agaataagga aaaagagaac tgctgaggtt gcaataaggg cttccctatg
    49921 ctgacctgat gcgtaagcca tctccagaac aatattggtt gttaaggttc tggttcctga
    49981 aaagagtcca cttggaataa ttggctggtt gcctgccacc aaaataactg ccatggtttc
    50041 acctactgcg cgaccgattc ctaaaataac tgctgataaa ataccagatc tcgcagctgg
    50101 caagatgaca ctaaaaatac tccgttcatg actagctcct agagccaagc taccagaata
    50161 atacgttttg ggaactgttc ggatagcaga ttctgacaaa ctgataatgg ttggcaaaat
    50221 cattattcct aatagtaacg aagcggttag gacactcatg ccatttccta aaaagcttct
    50281 aatccaaggc accaataatt gtaggccgaa aaaaccataa acaatagatg gaatggctgc
    50341 catcaagttg atagctgatt ttaagaagcc atagacgggc tttggacaat aataaaccat
    50401 aaacaccgat gtcaagatgc ctgttggcac cccaatcaca atcgctccta aggtaattaa
    50461 taaggaacca acgatcattg gtaaaatacc atagcttgcc ggaatgttcg ttggcgacca
    50521 atcactgcct aataaaaaac gggcaaagcc gtagttagct atgaaaggta agccattact
    50581 aaaaataaag aaacagatta gcaaaatagc tacaacagct actgttgcac tcatgaaaaa
    50641 aattgcccta aaaactgctt ctttgaaggc ttgttttgtc acatcttgtc ctttctagtg
    50701 aagaaagtaa gggagatacg acacctccct acttgccttc tttatcttat tgtacgatga
    50761 aacgtctgca tctctttaga gatttatgga gcaaacattt tatttaatct tgtcccaggt
    50821 ggttaatttg ccactaaaaa cgtctgcaag ttcagccata ctgacttggc ttgccttatt
    50881 gtcattattg accacaacag caataccgtc taaagcaata gcatcatggg tgagactctt
    50941 accttcttca ggagttaatt ccctagaaac cataccaata tcagcggttt tctccttaac
    51001 agcggtaata cctgctgaag acccattaga ggtaatatca atcgtaactt ctggattttc
    51061 ttttttataa gcttctgcta atttttccat taaagaagat actgaagtgg aacctacaac
    51121 agacaacttg cctgataagt gttggcttgt atattctgtg gtttcggttt tagcttcaat
    51181 aaatttatta tctgtgacca cttgttgacc ttgtttggag tggataaagc tgataaaatc
    51241 ttgacctagc ttggaaagat tagaagacca aacaatgttg aagggacgtt gaagagggta
    51301 tttaccatct aaaactgtgt ctcgactagc cttgacacca tcaatctcta aagctttgac
    51361 agatttcgtt aaagatccca aggagatgta gccgatagca ttagcattcc cttgaactgc
    51421 tgagagaaca ccttctgtac tattttgaat cacagctgtt ttggcagtgt tgtcaatttt
    51481 tttatcaccg tcttttttga gaatccctgt gatttctgtg aaggcacccc gtgttccaga
    51541 gccattttct cgtgaaatca cctcaatcgt tcctgaagct gactgtttgg aagcagctga
    51601 ctgattgcca caggcaacaa gcccaaatcc tgataagcca atggctgcaa gagtaagcat
    51661 ttttttgaat ttcataataa tcacctttat ctctatgtat ttttcttgtg taggcttact
    51721 acatttatag tctaacaagt ctttgtaaag gtttatccct gattcatgta aagattgtgt
    51781 aaagaatcaa aaaaagccac ttttgaaaaa tggctgctcc taaaaatagc tttaaaaatt
    51841 attagtcctg tgcgaaagat tggttaggaa gaaaaatcgt gaagcaactg cctctgccaa
    51901 gctgactcgt caccgtgact tggccaccta ataattgact gagttctttg acaatggcaa
    51961 ggccaagacc agtgccacca gtttgtctgc ttcgaccttt attaactcgg taaaaacgtt
    52021 caaaaatacg atcctgctct aattgactaa taccaatccc tgtatctgat acagaaatct
    52081 taatgccttc gttcaccttt tgggtcttga cctcaatttt tcccccttgt tcagtgtaac
    52141 ggatggcatt ggataaaaga ttgagtaaga tttgggaaag taattgacta tctgatacga
    52201 gggtgacatc atctggcacc tgcaccttta gctgtaaatc cttcttcttg agctgaggtt
    52261 gcaagctttg agtcaaatcc tgtacaaatt ctgccaaaga aagggtcgtc cattgtatag
    52321 gcatttgttg agccttagat aaggtaagaa gatgctcaac aatatgctca agacgcaagc
    52381 tttctttgta aataatgtct agaaagtcat ccttgagcgc ttcttcttca gctgacatcc
    52441 ccttaatggt ttcagcaaag cccttaatcg aagtaactgg tgtcctcaat tcatgggagg
    52501 catttgagac aaaggctaaa tttaactttt cataagttct aatcgttgtt aaatcatata
    52561 gcaagacgag cacagcttcc acagattggg tggggctaaa aacgggaact gctgtcactt
    52621 ctaaaatcaa gtcaccctca tgaaacccac ttacttcttg ttttaacctt gttttttgat
    52681 caaaggcttg gtgaactaaa tttcgaatat ccatccgttt gaggtcatca agtgaactta
    52741 tgtcgccgtc cacatcggga aaataatgag gcagagagcg actggataat aacatctgac
    52801 cttgagcgga aactaaaaac gtccccatgg ttaggtgcga cagaagaacc tccattgttt
    52861 cggctaggtc cttgtattgc tgatcctgtt gggagacttt ggtttttagg gcagacacat
    52921 actgagccaa agactttaag tcttcttgcc ctttttctaa aaagtattca ctactggtca
    52981 agagaggttg gtgcaaggtc tcaaaagcaa cttcccattt ccaaaggcaa aagagccagt
    53041 agccaccttg tcccaaagaa agggctagaa gaaagagacc gatgccttta ctgatccaag
    53101 ttaataccat ccctgcaatc agaatgaggc taacacttag attgactagc caaaattgaa
    53161 ggtagcgttt catctataac tccttgaact tataaccata accccgaatg gttcgaataa
    53221 attgaggggc tttaggattg tcttcaattt tttccctcaa cttaccaata tgaacgtcca
    53281 ccaaacgtgt ttcctgccca aagtcatacc cccagatacg ttccaaaaga cgctctctag
    53341 tcagtgtcat gttgggatgt ttcataagat agagcaagag ttcaaattct tttggggtca
    53401 aactcagtaa cttattcgcc ttgtagactt catgacgctc agggtatact ttcaaggtcc
    53461 caaatagcca agaatcgtca gcgatattat ctgaatcatc tccttcttgt tctcctttag
    53521 ttcgcctgag gacagccttg acacgcgcca gcaattctct agggctaaaa ggtttggtca
    53581 ggtagtcatc agcccctaat tccaaggcca aaaccttatc aaattcatca cttttcgcag
    53641 aaaccatcat aattggagtt ttgacgcctt tggctctcag ccgcttacaa acttccatgc
    53701 catctaattg tggtaacatg atatcaagca agataaaatc aaagggttct gtttctgcca
    53761 aagctaaggc cttccgtcca tttgttacca attgagtaga aaagccttcc ttacttaaat
    53821 ggtagtcaag caatttcaga atgtgttctt catcatccac taataagact tgttttgtca
    53881 tctattatct cctattggta acattataac acaattatca gaaatcctaa cattgctaaa
    53941 tcagattaaa tttgcttatc aagactagta tctggtcaaa cgctcaatca tctccttgtg
    54001 ctctggatag gtcgccagta gatctaccct ttcaaataat tcaaaatcct caaattcaaa
    54061 accaggagca acaagacaag aaaccagagc atcatcctta tcaactgttg atccccaaat
    54121 agtgccctta ggaacacagt agtgaagttg ttgccctttg gatatgtcca ggcctaaagt
    54181 gactgcttcg tagtgaccat ctgctgtaat catgtgaaca gtaagtgggg attctgcatg
    54241 aaaataccag atttcatctg ctgtcaatcg gtgaaaatgt gaaggattcg tttcttctta
    54301 ataagaaata aatactggta taaagcgccc ttcccttacc agcaaggttt atagtgtctg
    54361 aagctttttt tgtttgtcta aaatagccac cttcaacatg gggagctaac tctagagttc
    54421 ttatcaagtc ttctttatcc gtcggagcca atgggttgaa gtaactcttg ttcaaagtgg
    54481 tgttacgatt tcaagaactc ctctcagttc tgaggacacg gtaatgattg atgcgacgga
    54541 agtacaaatc aatcgcccta aaaaaagaat tagcgaatca ttctggtaaa aagaaatttc
    54601 acgctatgaa ggctcaagcg attgtcacaa gtcaagggag aattgtttct ttggatatcg
    54661 ctgtgaacta tagtcatgat atgaagttgt tcaaaatgag tcgcagaaat atcggacaag
    54721 ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac
    54781 aaattccacg taaatccagc aaactcaagc cgctaacagt tgaagataaa gcctgtaacc
    54841 atgcgctatc taaggagaga agcaaggttg agaacatctt tgccaaagta aaaacgttta
    54901 aaatgttttc aacaacctat cgaaatcatc gtaaacgctt cggattacga atgaatttga
    54961 ttgctggtat tatcaatcat gaactaggat tctagttttg caggaagtct attatttggt
    55021 taggtgaatt agtgaagcgt ttaggcaagt gtctctggtt acgacgtcat ggcctctaaa
    55081 tcgattatat ttaggggtca tgactagtga agcagttagc tagttcgcat ataagcggct
    55141 agcgtctaac aattaggaac tttagttcca ataactttaa gattacgacg ttttaggaca
    55201 taaatcgatc atatttatgt cctaaaacta gtgaagcgcc tagccaaagt ccgaatagga
    55261 tttggcgtta gttacttaga ttgctttgca atcaagtaac tttggcgatt tacatcttct
    55321 ctggtgcttc tactccaagc aagcgaaggg cttctttgag aacgactgcg gttgcgtagc
    55381 tgagggctag acggctgtcg cgttctgggc tttcatccaa gatacgtgta tgtgcatagt
    55441 atttgttaaa ggattgagcc aggctaattg caaatttagc aatgatagaa ggttcaaagt
    55501 tatctgccgc acggttgata atacgtggga agtcttgaat gagtttaatg atttcccagc
    55561 tttcagtatc attcaagcta tagttgccag ctgtttctgg tttgaaatcg gctttgcgta
    55621 agatagattg gatacgagcg taggcatatt gaacgtaagg tccagtttca ccctcgaagg
    55681 ataccatagc ttctaggtcg aagtcgtatc catttgtacg gtcagttttg aggtcataga
    55741 atttaatggc tccaacccca acagcatgtg ctacttggtc tttgttttct agttcaggat
    55801 ttttagcctc gatttggacc ttggcacggc taacagcctc tgcaacagta ggctctagca
    55861 agatgacatt ccctttacga gtagagagct tcttcccttc ttttgtaacc agaccaaaag
    55921 gaacgtgggt aatgtcgtca ctccaatcgt agcccatctc ttgcaagaca gctttgagtt
    55981 gtttaaagtg ggcagattgc tcttgaccaa cgacgtagat agatttagca aattggtatt
    56041 catttttacg gtagagggct gcagccaagt cacgtgtgat atagagagtt gcaccatcag
    56101 acttcttgat gagggctgga tgttcaattc catatttctc aagattcaca acttgggcac
    56161 cttctgattc aagaagtagt cctttttcag aaagaatgtc tacaactgca tccatcttat
    56221 cattgtagaa ggcttctccg ttatagctgt caaattcaac cttcaattca ttgtaaaggc
    56281 ggttaaattc cactaaactt tcatcgcgga accattgcca aagagcgaga gcttcctcat
    56341 ctccattttc aagtttacgg aaccattcgc gcgcttcttc atccaagcta gggtcatttt
    56401 cagcttcagc gttgatgcgg acatagagtt taaggagttc atcgattgga tgagctttta
    56461 cagcttcttc gtcgccccat tttttatagg caacaatcaa catcccaaat tgtttacccc
    56521 agtctcccaa atggttgacc ttgaccgttt gataaccgat tttttggaaa atatgtgaca
    56581 agctatctcc gataacagtt gaacgcaggt ggccaataga aaatggttta gcgatattcg
    56641 gactagacat gtcgataaca acattttctt gtttaccaat attttggtca gcatagtgtt
    56701 ctttttcagt ggtaacagct tgcaatactt gagcagaaat ggcagattta tcaaggaaaa
    56761 agttaacgta aggtcctgtt gcgacaactt tttcaaaggc ttggctgttc attttttcag
    56821 ccagttcagc cgcaatcatt tgtggtgctt tacgttcgac ttttgcaaga gaaaaagcag
    56881 ggaaagcaat gtctcccatt tctgagtttt taggggtttc cagtaacttt aaaacagcct
    56941 cttggtccag gctatcaatg atgctagata attcgctagc aatcaattct tttgtattca
    57001 ttaagagctc ctttttggac ttttctacta ttttatcaca attttaaaga aagaagaaaa
    57061 aatttttgaa atctcctgtt tttttggtat aatatggtta taaatatagt tataaatatg
    57121 cacgcaagag gattttatga gaaaaagaga tcgtcatcag ttaataaaaa aaatgattac
    57181 tgaggagaaa ttaagtacac aaaaagaaat tcaagatcgg ttggaggcgc acaatgtttg
    57241 tgtgacgcag acaaccttgt ctcgtgattt gcgcgaaatc ggcttgacca aggtcaagaa
    57301 aaatgatatg gtgtattatg tactagtaaa tgagacagaa aagattgatt tggtggaatt
    57361 tttgtctcat catttagaag gtgttgcaag agcagagttt accttggtgc ttcataccaa
    57421 attgggagaa gcctctgttt tggcaaatat tgtagatgta aacaaggatg aatggatttt
    57481 aggaacagtt gctggtgcca ataccttatt ggttatttgt cgagatcagc acgttgccaa
    57541 actcatggaa gatcgtttgc tagatttgat gaaagataag taaggtcttg ggagttgctc
    57601 tcaagactta tttttgaaaa ggagagacag aaaatggcga tagaaaagct atcacccggc
    57661 atgcaacagt atgtggatat taaaaagcaa tatccagatg cttttttgct ctttcggatg
    57721 ggtgattttt atgaattatt ttatgaggat gcggtcaatg ctgcgcagat tctggaaatt
    57781 tccttaacga gtcgcaacaa gaatgccgac aatccgatcc ctatggcggg tgttccctat
    57841 cattctgccc aacagtatat cgatgtcttg attgagcagg gttataaggt ggctatcgca
    57901 gagcagatgg aagatcctaa acaagcagtt ggggttgtta aacgagaggt tgttcaggtc
    57961 attacgccag ggacagtggt cgatagcagt aagccggaca gtcagaataa ttttttggtt
    58021 tccatagact gcgaaggcaa tcaatttggc ctagcttata tggatttggt gacgggtgac
    58081 ttttatgtga caggtctttt ggatttcacg ctggtttgtg gggaaatccg taacctcaag
    58141 gctcgagaag tggtgttggg ttatgacttg tctgaggaag aagaacaaat cctcagccgc
    58201 cagatgaatc tggtactctc ttatgaaaaa gaaagctttg aagaccttca tttattggat
    58261 ttgcgattgg caacggtgga gcaaacggca tctagtaagc tgctccagta tgttcatcgg
    58321 actcagatga gggaattgaa ccacctcaaa cctgttatcc gctacgaaat taaggatttc
    58381 ttgcagatgg attatgcgac caaggctagt ctggatttgg ttgagaatgc tcgctcaggt
    58441 aagaaacaag gcagtctttt ctggcttttg gatgaaacca aaacggctat ggggatgcgt
    58501 ctcttgcgtt cttggattca tcgccccttg attgataagg aacgaatcgt ccaacgtcaa
    58561 gaagtagtgc aggtctttct cgaccatttc tttgagcgta gtgacttgac agacagtctc
    58621 aagggtgttt atgacattga gcgcttggct agtcgtgttt cttttggcaa aaccaatcca
    58681 aaggatctct tgcagttggc gactaccttg tctagtgtgc cacggattcg tgcgatttta
    58741 gaagggatgg agcaacctac tctagcctat ctcatcgcac aactggatgc aatccctgag
    58801 ttggagagtt tgattagcgc agcgattgct cctgaagctc ctcatgtgat tacagatggg
    58861 ggaattatcc ggactggatt tgatgagact ttagacaagt atcgttgcgt tctcagagaa
    58921 gggactagct ggattgctga gattgaggct aaggagcgag aaaactctgg tatcagcacg
    58981 ctcaagattg actacaataa aaaggatggc tactattttc atgtgaccaa ttcgcaacta
    59041 ggaaatgtgc cagcccactt tttccgcaag gcgacgctga aaaactcaga acgctttgga
    59101 accgaagaat tagcccgtat cgagggagat atgcttgagg cgcgtgagaa gtcagccaac
    59161 ctcgaatacg aaatatttat gcgcattcgt gaagaggtcg gcaagtacat ccagcgttta
    59221 caagctctag cccaaggaat tgcgacggtt gatgtcttac agagtctggc ggttgtggct
    59281 gaaacccagc atttgattcg acctgagttt ggtgacgatt cacaaattga tatccggaaa
    59341 gggcgccatg ctgtcgttga aaaggttatg ggggctcaga cctatattcc aaatacgatt
    59401 cagatggcag aagataccag tattcaactg gttacagggc caaacatgag tgggaagtct
    59461 acctatatgc gtcagttagc catgacggcg gttatggccc agctgggttc ctatgttcct
    59521 gctgaaagcg cccatttacc gatttttgat gcgattttta cccgtatcgg agcagcagat
    59581 gacttggttt cgggtcagtc aacctttatg gtggagatga tggaggccaa taatgccatt
    59641 tcgcatgcga ccaagaactc tctcattctc tttgatgaat tgggacgtgg aactgcaact
    59701 tatgacggga tggctcttgc tcagtccatc atcgaatata tccatgagca catcggagct
    59761 aagaccctct ttgcgaccca ctaccatgag ttgactagtc tggagtctag tttacaacac
    59821 ttggtcaatg tccacgtggc aactttggag caggatgggc aggtcacctt ccttcacaag
    59881 attgaaccgg gaccagctga taaatcctac ggtatccatg ttgccaagat tgctggcttg
    59941 ccagcagacc ttttagcaag ggcggataag attttgactc agctagagaa tcaaggaaca
    60001 gagagtcctc ctcccatgag acaaactagt gctgtcactg aacagatttc actctttgat
    60061 agggcagaag agcatcctat cctagcagaa ttagctaaac tggatgtgta taatatgaca
    60121 cctatgcagg ttatgaatgt cttagtagag ttaaaacaga aactataaaa ccaagactca
    60181 ctagttaatc tagctgtatc aaggagactt ctttgacaat tctccacttt tttgctagaa
    60241 taacatcaca caaacagaat gaaaaggagc tgacgcattg tcgctccctt ttgtctattt
    60301 tttaaggaga aagtatgctg attcagaaaa taaaaaccta caagtggcag gccttggctt
    60361 cgctcctgat gacaggcttg atggttgcta gttcacttct gcaaccgcgt tatctgcagg
    60421 aagtattaga cgccctcctt actgggaaat atgaagctat ttatagtatc ggggcttggt
    60481 tgattggtgt ggccgtagtc ggtctagttg ctggtggact caatgttgtc ctcgcagcct
    60541 atattgccca aggagtttca tccgaccttc gggaggatgc cttccgtaaa attcaaacct
    60601 tttcttatgc tgatattgaa caatttaatg cgggaaatct agtcgttcga atgacaaatg
    60661 atatcaacca gattcagaac gttgtcatga tgaccttcca aattcttttc agacttcccc
    60721 tcttgttcat cggttcgttt atcctagcgg ttcaaacctt accttctctg tggtgggtga
    60781 ttgttctcat ggtagtcttg atttttggtt tgactgctgt catgatggga atgatggggc
    60841 ctcgttttgc caagtttcaa acccttcttg agcgcatcaa tgccattgcc aaggaaaatt
    60901 tacgtggcgt tcgtgtggtc aagtcctttg tccaagaaaa agagcaattt gctaagttta
    60961 cagaggtctc agacgagctt tttggtcaaa acctttacat tggttatgcc ttttcagtag
    61021 tggaaccctt tatgatgttg gttggttacg gggcggtctt cctctctatt tggctggtcg
    61081 cgggaatggt tcagtcggat ccgtctgttg ttggttccat cgcttctttt gttaattacc
    61141 taagccagat tatctttacc attgttatgg ttggattttt gggaaattct gtcagccgtg
    61201 ccatgatttc catgcgtcgt attcgagaaa ttcttgacgc agagccagct atgaccttca
    61261 aggatatccc agatgaagag ttggttggaa gccttagctt tgaaaatgtg acctttacct
    61321 atccaatgga caaggaaccg atgctgaaag atgtgagctt tactattgaa cctggtcaaa
    61381 tggttggtgt agttggagcg actggtgcag gaaagtcaac cttggctcaa ttgattccac
    61441 gtctctttga tccacagaac ggggccatta aaatcggtgg caaggatatt cgagaagtga
    61501 gtgaaggaac cctgcgtaaa acagtttcca tcgttctcca acgtgccatt ctttttagtg
    61561 gaacgattgc agataacttg agacagggga agggaaatgc tactctattt gaaatggagc
    61621 gcgcagccaa tattgcccag gctagtgaat tcattcatcg tatggagaaa acctttgaaa
    61681 gtccagttga agaacgggga accaatttct ctggtggaca aaaacaaagg atgtcgattg
    61741 cgcgtgggat tgtcagcaat ccacgtattc tgatttttga tgattcgacc tcagccttgg
    61801 atgccaaatc agagcgcttg gtgcaagaag ctttgaataa ggacttgaag gggacgacaa
    61861 ccattattat tgctcaaaaa attagctcgg ttgtccatgc agacaagatc ttggttctaa
    61921 atcaaggacg attgattggt caaggtacgc atgcagactt ggttgccaac aatgccgttt
    61981 accgtgaaat ctatgaaaca cagaaatgaa agacaaacta taagaaaagt caatagtttt
    62041 atctaaacta tttcttattt caatttgatg atttggcgat gattttagag cacggcaaaa
    62101 ggcccttgaa aaagtccatt ttttcaaagg taatcctgtg ttaatttcag aaattacatc
    62161 actttttgtt cgtcaaatgg cagctctttt tttaggatat aaaacagggt tcggataagt
    62221 ttttttgcaa ggtggatgat ggctacattg taatgttttc cttgttctaa tttagtctta
    62281 agataggcct taaaagcagg cgaaaagcga gggcatgctt tggcagcttg tatgagtacc
    62341 taccgcagat gaggggaact ccgtttgacc attcttcctg ctaaatcaat ctgatctgac
    62401 tgataaatag aagaatccag tccagcgaaa gcttgtaatt gagcaggatt atcaaaggca
    62461 tgaatatttc gaatctcagc taaaatgacc gcccctaaac gatccccaat cccagtaacc
    62521 gtcgtgatga ccgagttgaa ctcagccatc aagtcattga cacatgtttc cgccttgtca
    62581 atgagcccct tgtaatgttt gatgttttca ttacacgaga taaaacgtct atgcgttatc
    62641 aaactcatta ccaattaaaa caaaaagctg tggttagatc ctttcggaaa ttgtcaagcg
    62701 attggaggaa atgaactaat ccacagcggc ttattccaag tataccactt gggctttggc
    62761 agtagctaac tgcgctaaat ataatataag gaggagtaaa atgaagacag ttcaattttt
    62821 ttggcattat tttaaggtct acaagttctc atttgtagtt gtcatcctga tgattgttct
    62881 ggcgactttt gcccaagccc tctttccagt cttttctgga caagcggtga cgcagctagc
    62941 caatttagtt caagctcatc aaaatggcaa tccagaactt gtatggcaaa gcctatcagg
    63001 aatcatggtc aatcttggcc tgctggtttt ggttctattt atctctagtg taatatacat
    63061 gtgtctcatg acgcgcgtga ttgcagaatc gaccaacgag atgcgcaaag gtctctttgg
    63121 taagcttgct cagttgacgg tttctttctt tgaccgtcga caagatggcg atatcctgtc
    63181 tcattttacc agtgatttgg ataatatcct ccaagccttt aacgaaagct tgattcaggt
    63241 catgagcaat attgttttat acattggtct gattcttgtc atgttttcga gaaatgtgac
    63301 gctggctctc atcaccattg ccagcacccc attggctttc cttatgctga ttttcatcgt
    63361 gaaaatggca cgcaaataca ccaacctcca gcagaaagag gtagggaagc tcaacgccta
    63421 tatggatgag agcatttcag gccaaaaagc cgtgattgtg caaggaattc aagaggatat
    63481 gatggcagga tttcttgaac aaaatgagcg cgtgcgcaag gcaaccttta aaggaagaat
    63541 gttctcagga attcttttcc ctatcatgaa tgggatgagc ctgattaata cagccatcgt
    63601 catctttgct ggttcggctg tacttttgaa tgataagtct attgaaacaa gtacagccct
    63661 aggtttgatt gttatgtttg cacaattttc acagcagtac taccagccta ttatccaagt
    63721 tgcagcgagt tggggaagcc ttcagttggc ctttactgga gctgaacgaa ttcaggaaat
    63781 gtttgatgca gaggaggaaa tccgacctga aaaggctcca accttcacta agttgcaaga
    63841 aagtgttgaa atcagtcata tcgatttttc atacttgcct gataaaccta ttttgaaaga
    63901 tgtcagcatt tctgccccta aaggccagat gacagcagtt gttgggccga caggttcagg
    63961 aaaaacgact attatgaacc tcatcaatcg cttttatgat gttgatgctg gtggtattta
    64021 ttttgatggt aaagacattc gtggctatga cttagatagt cttagaagca aggtgggaat
    64081 tgtattgcaa gattcggtct tgtttagcgg aacgattcga gacaatatcc gatttggtgt
    64141 gccagatgct agtcaggaaa tggttgaggt agcagcaaaa gcaacccaca ttcacgacta
    64201 tatcgaaagt ttgcctgata agtacgatac tcttattgat gatgaccaga gcatcttttc
    64261 aacagggcag aagcaattga tttcaatcgc tcgaaccctg atgacagatc cagaagttct
    64321 cattctcgat gaagcaactt caaacgtaga tacggtgaca gaaagcaaga ttcagcatgc
    64381 catggaggtg gttgtagcag gtagaactag tttcgtcatt gcccaccgct tgaaaaccat
    64441 tctcaatgca gatcagatta ttgtccttaa agatggagaa gtcattgaac gtggtaacca
    64501 ccatgaactt ttgaagctag gtggctttta ttcagaactc tatcacaatc aatttgtttt
    64561 cgaataagaa agaagttgtc ctatgtgggc agctttttct tgtccataaa aaatgtttat
    64621 cacagcctta aaaaaaacat attagacgaa agtcattttg agtgatatga taggactatc
    64681 gttagcattc gaaaggagag gcatcatggc tagaacggtt gtaggagttg ctgcaaatct
    64741 atgtcccgta gacgcagaag gcaaaatcat tcattcatct gtatcttgta gattcgcaga
    64801 gatcattcgt caagtcggtg gtctcccttt agtcattcct gttggtgatg agtcagttgt
    64861 acgtgattat gtggaaatga ttgacaaact cattttgaca ggaggccaaa atgttcatcc
    64921 tcagttttat ggagagaaga agaccgtcga gagcgatgat tacaatctgg tccgtgacga
    64981 atttgaattg gcactcttga aggaagcgct tcgtcagaat aaaccaatta tggcaatctg
    65041 tcgcggtgtc caacttgtca atgttgcctt tggtggaacc ctcaatcaag aaatcgaagg
    65101 tcactggcaa ggactacctt tcgggacatc tcactctatt gagacagtag aaggaagcgt
    65161 ggtggctaag ctatttggga aagaaagtca ggtcaactca gtccatcgtc aaagcattaa
    65221 agatttggca cctaatttcc gtgtaactgc tattgattca agagaccaaa ctattgaagc
    65281 gattgagtct atcgacgagc accgcattat cggtttacag tggcatccag agtttctggt
    65341 taatgaagaa gatggcaatt tagaattatt tgagtattta ttgaatgaac tgtaacgatt
    65401 ggaacatctg gtcgttcttt cttttatttt ttcaaaattt ttagaatgtg gcattttacg
    65461 caaacgtttg aattctgata aaaattggag aaattcgaca aaaaaacttg aaaaaaacga
    65521 aggtaagcgt tatgatagaa aagaagaaat attggaggaa gaacatgtca catattaaat
    65581 ttgattattc aaaagtttta gacaaatttg ttgcaccaca tgaagtggaa tacatgcaat
    65641 cacaagtaac agcagcagat gaattgatcc gtaaaggaac tggtgctggt agcgacttct
    65701 tgggatggtt ggaccttcct gaaaaatacg accgcgaaga atttgaccgc atcttgaaag
    65761 ctgctgagca aatcaagtca gacagcgatg ttttggttgt gatcggtatt ggtggatctt
    65821 accttggtgc aaaagcagca atcgacttct tgaatcacca ttttgctaac ttgcaaacaa
    65881 aagaagaacg caaagctcca caaatccttt acgcaggaaa ctcaatctca tctacttacc
    65941 ttgctgactt ggtagagtat gttgcagaca aagacttctc agtaaacgta atttctaaat
    66001 caggtacaac aactgaacca gcgattgctt tccgtgtctt taaagaactc ttggttaaga
    66061 aatacggtca agaagaagct aacaaacgta tctatgcaac aactgaccgc caaaagggtg
    66121 ctgttaaggt tgaagcagac gctaacggtt ggggaacatt tgttgttcca gatgatatcg
    66181 gtggacgctt ctcagtattg acagccgttg gtttgcttcc aatcgcagca tcaggagctg
    66241 acataaaagc tcttatggaa ggtgcgaatg cagctcgcaa agactacact tcagacaaaa
    66301 tctctgaaaa cgaagcttac caatacgcag tcgttcgtaa catcctttat cgtaaaggct
    66361 atgcaactga gatcttggta aactatgagc catcacttca atacttctca gaatggtgga
    66421 aacaattggc tggtgaatca gaaggaaaag accaaaaagg tatctaccca acttcagcca
    66481 acttctcaac tgacttgcac tcacttggtc aatttatcca agaaggaact cgtatcatgt
    66541 ttgaaacagt tgtccgtgtt gacaaacctc gtaaaaacgt gcttattcct actttggaag
    66601 aagaccttga cggacttggt taccttcaag gaaaagacgt tgactttgta aacaaaaaag
    66661 caactgacgg tgttcttctt gcccacacag atggtgatgt accaaacatg tatgtgactc
    66721 ttccagagca agacgctttc actcttggtt acactatcta cttcttcgaa ttggcaattg
    66781 ccctttcagg ttacttgaat gctatcaacc catttgacca accaggtgtt gaagcttata
    66841 aacgtaacat gtttgccctt cttggaaaac caggatttga agaattgagc aaagaactta
    66901 acgcacgtct ataatagaag aaaagagtgg tttgcccact ctttttactc tctttatcca
    66961 tagaaattgg actcagccaa gacttgtgat ataatataga aagcaaaaag gcagacgcct
    67021 agataatagg agaaactatg tcaaaagata tccgcgtacg ttacgcacca agtccaacag
    67081 gactactaca catcggaaat gcccgtacag cattgtttaa ctacttgtat gcgcgccatc
    67141 atggtggaac atttctcatc cgtatcgaag atactgaccg taaacgccat gtcgaggatg
    67201 gtgaacgttc acaacttgaa aaccttcgct ggttaggcat ggattgggat gaaagtccag
    67261 aatcacatga gaattatcgc cagtctgagc gtttggactt gtatcaaaaa tacatcgacc
    67321 aactattagc tgaaggaaaa gcctacaaat cttacgttac agaagaagag ttggcagctg
    67381 aacgtgaacg tcaagaagta gctggcgaaa caccacgcta catcaatgaa taccttggta
    67441 tgagtgaaga agaaaaagca gcttacatcg cagaacgtga agcagcaggg atcatcccaa
    67501 ctgttcgttt ggctgtcaat gagtcaggta tctacaagtg gcatgatatg gtcaaaggcg
    67561 atatcgaatt tgaaggtggc aatatcggtg gtgactgggt tatccaaaag aaagacggtt
    67621 acccaactta caactttgcc gttgttatcg atgaccacga tatgcaaatc tctcatgtta
    67681 tccgtggaga tgaccatatt gctaatacac caaaacagct tatggtctat gaagctcttg
    67741 gttgggaagc tccagagttc ggtcacatga ccttgattat caactctgag actggtaaga
    67801 agttatctaa acgtgatact aatacacttc aatttatcga agattaccga aagaaaggtt
    67861 accttccaga agcagtcttt aactttattg ctcttcttgg ttggaaccca ggtggtgaag
    67921 atgagatttt ctctcgtgaa gaactcatta aactttttga tgaaaaccgc ctcagcaagt
    67981 caccagcagc ctttgatcag aaaaaactag actggatgag caatgattat atcaagaatg
    68041 cagaccttga aaccatcttt gaaatggcaa aaccattctt agaggaagca ggccgtttga
    68101 ctgacaaggc tgaaaaatta gttgagctct ataaaccaca aatgaaatca gtagatgaga
    68161 ttatcccatt gacagatctt ttcttctcag atttcccaga attgacagaa gcagagcgcg
    68221 aagtcatgac gggtgaaaca gttccaacag ttcttgaagc attcaaagca aaacttgaag
    68281 cgatgacaga tgataaattt gtgacagaaa atatcttccc acaaattaaa gcagttcaaa
    68341 aagaaacagg tattaaaggg aaaaatcttt tcatgcctat tcgtatcgca gtttcaggcg
    68401 aaatgcatgg gccagaatta ccagatacaa ttttcttgct tggacgtgaa aaatcaattc
    68461 agcatatcga aaacatgcta aaagaaatct ctaaataaag aggatacaat aatggacatc
    68521 tgggaaaaga tgtacgaaga agcacagaaa ctatacaatc cacatgaagt atcagacttt
    68581 gtttatgcca atcatgttgt agctgcagta gaagcagaag atggacaaat atttacagga
    68641 ttctgtatgg agggaacctg tggtgttttc catctctgcg cagaacgggc gaccctcttc
    68701 aatatgtacc aattttcagg acaaactaag gttaagaaag tattagcctt tcgagacaaa
    68761 ccaccttatg gtggaagttc agccatgcct tgcggtgctt gtagagaatt ccttttagag
    68821 cttaatgctg aaaataaaga tgcagaattc atgatggact ataatataag aaaaacagtt
    68881 aaagtcgcag aactaatccc ttattggtgg ggagaagaac gtgcttctaa gtttaatgag
    68941 cgatagaaga gtcagtataa ttctggcttt ttttactata agttgaaaaa at
//
LOCUS       DAVKMJ010000005        56957 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000005 DAVKMJ010000000
VERSION     DAVKMJ010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56957
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.005"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..137)
                     /locus_tag="VW348_000306"
     CDS             complement(<1..137)
                     /locus_tag="VW348_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9745283.1"
                     /translation="MNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRLLLAYQQK
                     G"
     gene            307..378
                     /locus_tag="VW348_000307"
     tRNA            307..378
                     /locus_tag="VW348_000307"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:340..342,aa:Glu,seq:ttc)
     gene            384..457
                     /locus_tag="VW348_000308"
     tRNA            384..457
                     /locus_tag="VW348_000308"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:418..420,aa:Asn,seq:gtt)
     gene            complement(498..1040)
                     /locus_tag="VW348_000309"
     CDS             complement(498..1040)
                     /locus_tag="VW348_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEU9745284.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            complement(1300..2553)
                     /locus_tag="VW348_000310"
     CDS             complement(1300..2553)
                     /locus_tag="VW348_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEU9745285.1"
                     /translation="MKCFVGLDISSTKLDVCIMLSDTSTPVTASLSNDLSGATEIKNH
                     ILDLNHTYHFERIVIGMEATSLYSFHPAMFFHEDRQLKELHVEIMVEQPNKIKKYRDA
                     FEENKNDTIDAFYIADYFRIERFSPSFLKEEKYMALQHLTRTRLQIIEQLTRTKQHFI
                     ENIYYKCNTLAYQFKKEELSTNLWSSTMMTLMTDEMTLDELANMPLQELDDWLQKLGK
                     GHFKDSEKLAQTIQAAIRGSYRLSKLQQDSVNVILGLLAREIRNLEKMIKEIDKAIED
                     MVETIPEYQCLTSIPGVGKVYAAGIIAEIGQIERFKDHPQVAKFAGLNWREKQSGNSN
                     SQHTSLVNRGNRYLRYYLVEAANSVRRYDDEYKDFYKKKYHEVPKHQHKRAILLTARK
                     FVRLVDVLLRNHQLYTPPRRIMEDN"
     gene            2909..4667
                     /locus_tag="VW348_000311"
                     /pseudo
     CDS             2909..4667
                     /locus_tag="VW348_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
     gene            complement(4697..7240)
                     /locus_tag="VW348_000312"
     CDS             complement(4697..7240)
                     /locus_tag="VW348_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEU9745286.1"
                     /translation="MKSFLKTYRTYFISLIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLSPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYTLMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVLFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVTGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSTYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVDFDY
                     FSPIPYEKIENTNNLISVTSSSNEDAAIQYQIEVPENSQIYLSFINLHFSNDKQKKVD
                     ILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTKTFT
                     EAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQAQT
                     GFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(7302..8924)
                     /locus_tag="VW348_000313"
     CDS             complement(7302..8924)
                     /locus_tag="VW348_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9745287.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            9130..10155
                     /gene="trpS"
                     /locus_tag="VW348_000314"
     CDS             9130..10155
                     /gene="trpS"
                     /locus_tag="VW348_000314"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEU9745288.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            10307..11785
                     /gene="guaB"
                     /locus_tag="VW348_000315"
     CDS             10307..11785
                     /gene="guaB"
                     /locus_tag="VW348_000315"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEU9745289.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(11836..12933)
                     /gene="recF"
                     /locus_tag="VW348_000316"
     CDS             complement(11836..12933)
                     /gene="recF"
                     /locus_tag="VW348_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEU9745290.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(12936..13304)
                     /gene="yaaA"
                     /locus_tag="VW348_000317"
     CDS             complement(12936..13304)
                     /gene="yaaA"
                     /locus_tag="VW348_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEU9745291.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            13463..14713
                     /locus_tag="VW348_000318"
     CDS             13463..14713
                     /locus_tag="VW348_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU9745292.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPAVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            14710..15993
                     /locus_tag="VW348_000319"
     CDS             14710..15993
                     /locus_tag="VW348_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEU9745293.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGYVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTIDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            16035..16856
                     /locus_tag="VW348_000320"
     CDS             16035..16856
                     /locus_tag="VW348_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9745294.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            16867..17412
                     /gene="pgsA"
                     /locus_tag="VW348_000321"
     CDS             16867..17412
                     /gene="pgsA"
                     /locus_tag="VW348_000321"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEU9745295.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            17409..18236
                     /locus_tag="VW348_000322"
     CDS             17409..18236
                     /locus_tag="VW348_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU9745296.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            18221..19060
                     /locus_tag="VW348_000323"
     CDS             18221..19060
                     /locus_tag="VW348_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEU9745297.1"
                     /translation="MGIALENVNFIYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPSILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            19053..19847
                     /locus_tag="VW348_000324"
     CDS             19053..19847
                     /locus_tag="VW348_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU9745298.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            19906..20724
                     /gene="mreC"
                     /locus_tag="VW348_000325"
     CDS             19906..20724
                     /gene="mreC"
                     /locus_tag="VW348_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEU9745299.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            20724..21218
                     /gene="mreD"
                     /locus_tag="VW348_000326"
     CDS             20724..21218
                     /gene="mreD"
                     /locus_tag="VW348_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEU9745300.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGIYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            21312..22490
                     /locus_tag="VW348_000327"
     CDS             21312..22490
                     /locus_tag="VW348_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEU9745301.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            22714..23493
                     /gene="rpsB"
                     /locus_tag="VW348_000328"
     CDS             22714..23493
                     /gene="rpsB"
                     /locus_tag="VW348_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEU9745302.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNK"
     gene            23559..24599
                     /locus_tag="VW348_000329"
     CDS             23559..24599
                     /locus_tag="VW348_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEU9745303.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            24845..25168
                     /gene="tnpB"
                     /locus_tag="VW348_000330"
     CDS             24845..25168
                     /gene="tnpB"
                     /locus_tag="VW348_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HEU9745304.1"
                     /translation="MIIQLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSDQV
                     FLFCGGRKDRFKVLYWDGQGFWILYKRFENGKLTWSSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
     gene            complement(25309..25596)
                     /locus_tag="VW348_000331"
                     /pseudo
     CDS             complement(25309..25596)
                     /locus_tag="VW348_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            25587..25985
                     /locus_tag="VW348_000332"
     CDS             25587..25985
                     /locus_tag="VW348_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9745305.1"
                     /translation="MKAPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPITRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(26182..27102)
                     /gene="cysK"
                     /locus_tag="VW348_000333"
     CDS             complement(26182..27102)
                     /gene="cysK"
                     /locus_tag="VW348_000333"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEU9745306.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(27387..28022)
                     /locus_tag="VW348_000334"
     CDS             complement(27387..28022)
                     /locus_tag="VW348_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEU9745307.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHGLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            28078..29376
                     /locus_tag="VW348_000335"
     CDS             28078..29376
                     /locus_tag="VW348_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9745308.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQVVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            29373..30035
                     /locus_tag="VW348_000336"
     CDS             29373..30035
                     /locus_tag="VW348_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEU9745309.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            30115..30663
                     /gene="raiA"
                     /locus_tag="VW348_000337"
     CDS             30115..30663
                     /gene="raiA"
                     /locus_tag="VW348_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEU9745310.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            30799..32772
                     /locus_tag="VW348_000338"
     CDS             30799..32772
                     /locus_tag="VW348_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEU9745311.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            32769..33221
                     /gene="rplI"
                     /locus_tag="VW348_000339"
     CDS             32769..33221
                     /gene="rplI"
                     /locus_tag="VW348_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEU9745312.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            33265..34617
                     /gene="dnaB"
                     /locus_tag="VW348_000340"
     CDS             33265..34617
                     /gene="dnaB"
                     /locus_tag="VW348_000340"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEU9745313.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            34619..34885
                     /locus_tag="VW348_000341"
     CDS             34619..34885
                     /locus_tag="VW348_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745314.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            34974..36320
                     /gene="cbpD"
                     /locus_tag="VW348_000342"
     CDS             34974..36320
                     /gene="cbpD"
                     /locus_tag="VW348_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEU9745315.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRI
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      36403..36505
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            36576..36866
                     /locus_tag="VW348_000343"
     CDS             36576..36866
                     /locus_tag="VW348_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEU9745316.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQGADNVFSNVKINVGEILSIDEKLEKYTETTH"
     gene            36829..37587
                     /locus_tag="VW348_000344"
     CDS             36829..37587
                     /locus_tag="VW348_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9745317.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWFNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            37625..38632
                     /locus_tag="VW348_000345"
     CDS             37625..38632
                     /locus_tag="VW348_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9745318.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            38632..39360
                     /locus_tag="VW348_000346"
     CDS             38632..39360
                     /locus_tag="VW348_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9745319.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPQGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            39479..39937
                     /locus_tag="VW348_000347"
     CDS             39479..39937
                     /locus_tag="VW348_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEU9745320.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            39939..42371
                     /locus_tag="VW348_000348"
     CDS             39939..42371
                     /locus_tag="VW348_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU9745321.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVFYAILHDGNALATRILERAGFSYEDKKDQVKIATLRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            42692..43345
                     /gene="rr06"
                     /locus_tag="VW348_000349"
     CDS             42692..43345
                     /gene="rr06"
                     /locus_tag="VW348_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEU9745322.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            43342..44673
                     /gene="hk06"
                     /locus_tag="VW348_000350"
     CDS             43342..44673
                     /gene="hk06"
                     /locus_tag="VW348_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEU9745323.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            44768..45295
                     /locus_tag="VW348_000351"
     CDS             44768..45295
                     /locus_tag="VW348_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEU9745324.1"
                     /translation="MVLAIILVIFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     LAHIVFYLSCLVEAMVHKTMFDGMSMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            45374..47332
                     /gene="pspC"
                     /locus_tag="VW348_000352"
     CDS             45374..47332
                     /gene="pspC"
                     /locus_tag="VW348_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEU9745325.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVAVASLVMGSVVHATEKEVTT
                     QVPTYSNMAKTEHRKAAKQVVDEYIEKMLREIQLDRRKHTQNFAFNMKLSAIKTEYLY
                     GLKEKSEAELPSEVKAKLDAAFEQFKKDTLKLGEKVAEAEKKVAEAEKKAKAQKEEDR
                     RNYPTITYKTLDLEIAESDVEVKKAELELLKEEAKTRNKDTIKQAKAKVESKQAEATR
                     LEKIKTDRKKAEEEAKRKAAEEDKVKDKLKRRTKRAVPGEPATPDKKENGAKSSDSSV
                     GEETLPSPSLKPEKKVAEAEKKVAEAEKKAKDQKEEDRRNYPTNTYKTLELEIAESDV
                     KVKEAELELVKEEAKESRNEEKVKQAKAKVESKQAEATRLEKIKTDRKKAEEEAKRKA
                     AEEDKVKEKPAEQPQPAPAPQPEKPAPAPKPENPAEQPKAEKPADQQAEEDYARRSEE
                     EYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNS
                     NGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGSMATGWLQYNGSWYYL
                     NANGDMATGWLQNNGSWYYLNANGDMATGWVKDGDTWYYLEASGAMKASQWFKVSDKW
                     YYVNGSGALAVNTTVDGYGVNANGEWVN"
     gene            complement(47562..48542)
                     /gene="dusB"
                     /locus_tag="VW348_000353"
     CDS             complement(47562..48542)
                     /gene="dusB"
                     /locus_tag="VW348_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEU9745326.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(48529..49401)
                     /gene="hslO"
                     /locus_tag="VW348_000354"
     CDS             complement(48529..49401)
                     /gene="hslO"
                     /locus_tag="VW348_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEU9745327.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGAGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            49566..50993
                     /locus_tag="VW348_000355"
     CDS             49566..50993
                     /locus_tag="VW348_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9745328.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELAIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            51152..52660
                     /gene="glpK"
                     /locus_tag="VW348_000356"
     CDS             51152..52660
                     /gene="glpK"
                     /locus_tag="VW348_000356"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEU9745329.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            52702..54528
                     /gene="glpO"
                     /locus_tag="VW348_000357"
     CDS             52702..54528
                     /gene="glpO"
                     /locus_tag="VW348_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEU9745330.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKKEVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            54598..55302
                     /locus_tag="VW348_000358"
     CDS             54598..55302
                     /locus_tag="VW348_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEU9745331.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTVGVALKGDLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            55599..55802
                     /locus_tag="VW348_000359"
     CDS             55599..55802
                     /locus_tag="VW348_000359"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745332.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEGKKQELLNRLNK"
     gene            complement(55889..56497)
                     /locus_tag="VW348_000360"
     CDS             complement(55889..56497)
                     /locus_tag="VW348_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745333.1"
                     /translation="MSSISPSLVVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNI
                     LSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVN
                     TIHGNKQANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
BASE COUNT        17703 a         9717 c        12358 g        17179 t
ORIGIN      
        1 tttcctttct gttgataggc tagtaacaga cgattgattt gtctttcaga aagattgagt
       61 tcgacacagg cccgtttctt tgttttcttt ccttgggcta tagcttttat cacaagatat
      121 tttttcgttt cattcatatt cagttggatc cttttcatat gactattcta ccaaatggga
      181 cattttcacg ttcgatttac taaagacatt atcacattcg aattacatat tttagagaaa
      241 aaatctcaaa agtgattgac aattagcaag aaattgatat aatggttata tctgctacag
      301 atagaaggtc cgttggtcaa ggggttaaga caccgccttt tcacggcggt aacacgggtt
      361 cgaatcccgt acggactatt ttatccgcca tagctcagtt ggtagtagcg catgactgtt
      421 aatcatgatg tcgtaggttc gagtcctact ggcggagtat agataaaagg gaacacagct
      481 gtgttcctct ttttgtatca atttgtatca ccaagcattt tcataaggaa gtctgttatt
      541 tcttgagaac tttctttttt tccatgtgca atccaagttt ggcagacacc aaaaagtgca
      601 tgagttagat agatgctact atattctaat tcagtggtat ttagattcag ttgcataaat
      661 cgcttttgta aatctgtact aagcatgata tgaagtttat ttcgtaagaa attttggatt
      721 tctttagtcc cattttcaga aagaagggca gccagaagtg gttctgactc tagatattca
      781 aaaacttcta aaatagcgtc tcttttgtga tgagcatgtt tttgaaaaat atattcaaat
      841 gtatggaata gcttgctttg atagtgctca atcatatcat acttatcctt atagtgagta
      901 tagaagctgg aacgactaat tccggctttt tctactaatt tgacagtaga aattttatca
      961 aatggctgtt ccatcagtaa ttgtaccata gcgttttcaa tagttcgctt tgtttttaag
     1021 cgtttgttac tttcttgcat atttcctcct tgtaaacaaa ttagactata tgtctaaaaa
     1081 tagatttttt atcttgtaat ttagattttt taatgtataa tctattatat caaaatttta
     1141 gacaatatgt ttaaaaaagt ctagtggtaa aatgtcaagc gaccccccgc tcaaagtttg
     1201 aaaactattt caaaaaaagg gtgcactaaa gaagccctac tgaaaacgat gttttcacac
     1261 tgtttttagt agattttcaa ggagaggtgc agatataact tagttatctt ccataatcct
     1321 ccttggtggc gtatagagtt gatggttgcg tagtagcaca tccaccagac gcacaaattt
     1381 tctagcggtt agtaagatgg ctcgtttgtg ttggtgttta ggtacttcat ggtatttctt
     1441 cttatagaaa tccttgtatt cgtcatcata acgccttacc gagttggcgg cttcaaccag
     1501 gtagtagcgc agataacgat tgcccctatt cacaagcgaa gtatgttgtg agtttgagtt
     1561 accagattgc ttttctctcc aattcagacc agcaaatttt gcgacctggg gatggtcttt
     1621 aaagcgttcg atttgtccaa tttcggcaat gataccagca gcgtagacct tcccgacccc
     1681 aggtatggag gtcaggcatt gatattcagg aatggtttcc accatatctt caatggcctt
     1741 atcaatttcc ttgatcattt tttccaggtt tcgaatttcc cgagccagaa gtccgagaat
     1801 gacattgact gaatcttgtt ggagtttaga gaggcgataa gaacctctga tagcggcttg
     1861 aatggtttga gcaagcttct cagagtcctt aaaatgccct ttacccagtt tttggagcca
     1921 atcatctaat tcttgaagag gcatgttagc aagttcgtct aaggtcatct catctgtcat
     1981 caaggtcatc atcgttgaac tccataggtt agtagagagt tcttctttct tgaattgata
     2041 agccaaggta ttgcacttgt agtagatatt ttcaatgaag tgctgtttgg ttctggttaa
     2101 ttgctcgatg atttggagtc tggttcttgt gagatgttgg agagccatgt atttctcttc
     2161 ttttaaaaaa gaaggtgaaa atcgctcaat acggaaataa tccgcaatgt agaaagcatc
     2221 aatggtatcg tttttgtttt cttcgaaagc atcccgatac ttcttgattt tattaggttg
     2281 ttcgaccata atctcaacat gtagttcttt caactgccta tcttcatgga agaacatagc
     2341 agggtggaaa ctgtagagac tggttgcttc catgccaatg acaatccttt cgaagtgata
     2401 ggtatgattc aaatcaagga tatgattctt aatctctgtt gccccagaaa ggtcattaga
     2461 gagggaagca gtgacggggg tgctagtatc actcaacatg atacacacat ctaattttgt
     2521 agagctgatg tctaaaccga caaaacattt cattaaggaa ggtctccttt ccattagatt
     2581 tggaagtttt tttgactact gtaaggtttc ccagaaacac cttgttccaa catcctcgca
     2641 taagagaatc cttatcacag cctgacagag ccgcctgcat cctactagat acagaagtca
     2701 agctgtggaa acagctagtg tgttggaagt ttgaacaagg cttgggtaac agacttttta
     2761 atgaagtcca agcaacaagg agaaaaagaa acaaccatga gtccattcca tgactctatt
     2821 gttctagaaa accttgcaat agtcaagtga taacgaataa aacttgggat tgaaatatcc
     2881 ccatgattat atattacgag gagaaactat gtttaaagaa tggaaagcaa tttaaaaaaa
     2941 acaaccttta ttattgtcat gatcgggatt tctcttattc cagctctgta caatatcata
     3001 tttttgtcat caatgtggga tccatatggg caattgtctg acttacctgt ggcagttgta
     3061 aataatgata aagaggcttc ctataatggt aatactatgg caataggaaa agacatggtg
     3121 tccaatttaa aagaaaataa aaccttggat tttcattttg tagatgaaga ggaaggaaag
     3181 aagggattgg aagatggcga ttactatatg gtagtgactt taccaagtga tttatctgaa
     3241 aaagcaacta cattatccaa tattcaatcg acagcagctt atcaatcatt gacaagtgag
     3301 caacaaactg agataagtga ttctgtatct caaaattcaa ctgatagtat tcaatcggct
     3361 cagtcaattg tagctttagt acaagattta cagggaagtt tagaaaactt acaaaatcaa
     3421 tcttctaatc tttcgacttt aaaaaatcaa gctaatcaag tattacctat tacttctact
     3481 tctttgatag gattgtcaag tggattaaca gagatacaag gagctgttac tagcaaatta
     3541 gttcctgcca gtcagtcgat tgcatcaggt gtaaacgcat atactacagg tgttgataaa
     3601 gtttctcagg gcgcaagtca actaagtgaa aaaaatgcta ccttgacagg tagtttggat
     3661 caattagttt caggctcaaa caccttgaca caaaaatctt ctagcttgac agcaggagtt
     3721 ggtcaattag ttgaaaaaac tccagaatta gtatctggta ttgaaaaatt atcaactggc
     3781 tccaattaat tgaatcaaaa gagtcaagaa ttgatagcag gagttgataa attgcagtca
     3841 ggctctagcc aactagctga caaatccagt cagttacttt caggtgtttc tcaattagaa
     3901 agtggagcta ataaattggc agatggagct gggaaactag cagaaggtgg aacaaagtta
     3961 acttctggat tggaaggttt acagacagga cttgcttctt taggacaagg actaggtaat
     4021 gctagtgatc aactcaaatc agcatcaaca gaatctaaaa atgcagagat tttgtcaaat
     4081 ccactcaatc tttccaaaac agacaatgac caagttcctg taaatggaat tgcaatggct
     4141 ccttatatga tatcagttgc tctttttgtt gcagcaatat caacgaatat gatctttgcg
     4201 aagttacctt caggacgtca tccagagagc cgttgggctt ggttgaaatc tcgagctgaa
     4261 ataaatggta ttatagctgt tttggcaggg attttggtat atggaggagt tcatcttatt
     4321 ggtctaactg ctaatcatga aatgagaaca tttattctca tcatcttaac aagtttagta
     4381 ttcatgtcta tggtgaccgc tttaacaaca tggaatagcc gtataggagc tttcttctcg
     4441 cttatttttc ttttattaca gttagcatca agtgcaggta cctatccgct tgctttgaca
     4501 aatgatttct ttagagctat taatccttgg ttgccaatga gttattcagt ttcgggatta
     4561 cgacaaacaa tctccatcaa caagtcattt tcctagctgt catactagct ctatttactg
     4621 gtttaggtat gctagcctat caacctaaga aaatggaaga agattaaaaa aatcgaccga
     4681 ttaactggtc gattttttat gccttagatg actttcgtct gtgattatag attccaaata
     4741 gtaagagaga agtaaaggaa cagattgctc cagtaataaa accattggga atgaaggaaa
     4801 gtgtaatagt tcctttcccc ttgggaatgt caactttcat aaatccagtt tgagcttgtt
     4861 taatttctat tttcttacca tcttggtagg cagaccaacc tttgtcataa ggaatggtga
     4921 agaaaataga tgtatcttgt tggacatcat atgtagcaaa aaccttgttt ttagaagttg
     4981 atactgtgac aggttgttct ttaatttttt gaattgcctc ggtgaaagtt ttggtatcta
     5041 aacgatagaa ggtaggagat tcaaatgata cttgtgaatt tccagggaaa ctaacattga
     5101 tattgaaagt ttttttctct ttagtatatc ctagattaaa gaaggagaag acattatcag
     5161 ttgtaaaagt ctttttttca ccatttacaa ggatgtcaac cttcttttgt ttatcgttag
     5221 aaaagtgaag gtttatgaaa gagagataaa tttggctgtt ttctggaact tcaatttgat
     5281 actggattgc tgcatcctca tttgaagaac ttgtgacact aatcaaatta ttagtatttt
     5341 ctattttttc ataagggatt ggagaaaaat aatcaaaatc aacgttagca agttgattta
     5401 aaaacgaggc ctgattatcc aaggtatgtt cattgaactt gacatcattg taaacagatt
     5461 gactagcaac tgcaatcgga agagagtatt gattttcata tagggtaaga ttatcttttt
     5521 gatagatatc tttaaaacca tacttatcaa taggactgtc tgagatattg tactggatac
     5581 caaataaact atcagccaaa atactattat ttgcatatcg gagattgaga ttagtcccag
     5641 aggatttaaa cccaagttta tctaaagtag agcttgatga acgatttcga acagatgaaa
     5701 attgagagat tccattgtag ttgaatttca tactgtcatt tcctgtctga gtttgtagtt
     5761 tttcagtacg agtaaattga tttccaatat atgttgagaa agattccata gctgggatat
     5821 ctcgactata agtacttcga gaagcaaatc cccattcctt agcaattccg tccatttgag
     5881 atgaagcatt taaactcatt tcaaccagta taaataaaga gattagaatg gcaaatagat
     5941 tcacagatat aaactttttg ataactgcaa ggagtaaaag agaatagaca accaaaaatt
     6001 caagagtaag cagaatattc aaatctgtta aaaaagaata atgcgatttt agatagatgg
     6061 tagctaaaaa tcctgttact acaagaaaaa gcgaaactaa aaaattccag actttaagtt
     6121 ctttcagacg ctttaagact tctgctgctg tgtaaattaa caaggtagag aaaatccaag
     6181 catagcgatg taaaaacatg tttggagtat gcatgccttg ccaaaataag tcaagagctt
     6241 ctatgtaaaa gcttgcaatt agaaatgcaa agaataatac atatatgagt ttcacgtgaa
     6301 acttaataga tttcagcgta aaaaataaaa tggtcaaaat aaaaggaagt agtccaacaa
     6361 aaatcattgg gatggcccca tactttgttg tgtcaaagga accaatgaat tgcttagcaa
     6421 agagatcaag ataccagcta ctttcagttt gaaactttgt aacttcagtc aatttttccc
     6481 catgtgtctg taaatcaaac agagtgggaa gagtcataat caaactagcc ataccagcta
     6541 aaaaggagat aactatgaaa tcaagaacag atgattttcg agtcttaaag tcccacgaaa
     6601 tttgacagag ataccagaaa ataagaaaca atactgtcat atatccaaaa taataatttt
     6661 gaataaataa gattgacaga cttgtaaagt acaataggag tttcttttca gttatcagta
     6721 gatgtaaacc agttataatt aaaggaatca agataaaaac atctagccag gtttttatct
     6781 ctaattgact gacagtgaaa ctcatcagag tataggaagt agataaggct agttttaaag
     6841 tctgagggat agattgaaac aatttattca aactaaaaaa ggttgacaga ccaatcaatc
     6901 caaattttaa gagagtggtc agataaacag catctggcat attcgttaga tcaaaaaagt
     6961 aaaccagagg tgagagaaaa ctacccaagt aataactaga cagagcatag aagtttagcc
     7021 ctagaccact tgtaaaggtg taaaacagac tactatttcc atgtaggata tttcgtaagg
     7081 ctacatcaaa aataacgtat tgatgaaagc catctcctaa tagaggagag ttgtcgctat
     7141 tccagtagat accttgagat agatatactc cagacataat cactacagga atgatgagag
     7201 aaataaaata ggttcgatat gtttttaaaa atgatttcat gttacctcgt agaatgatag
     7261 aaaactcagt tggttaaccc aactgagttt tgaagtttta tttagtcttt ccaaagttct
     7321 ttaacttttg cttgtacttc tgcattttct aggaattcat cgtaggtttc atcgatacgg
     7381 tcaatgacgc catttttaga taagacaatg atatggttag ccaaagtttg aataaattcg
     7441 tggtcatggc tagcaaagat gattgattct ttaaagtttt tcaatccatc attcaagctt
     7501 gagatagatt ccaagtccaa gtgatttgtt ggatcatcaa gtacaaggac atttgatttt
     7561 aagagcatga gttttgaaag catgacacga actttttctc cccctgacaa gacatttaca
     7621 ggtttgttaa cttcatctcc agagaagagc atacggccga ggaagccacg taggaaagta
     7681 ttgtcatctt cttctttact tgcgaattga cgcaaccagt caagaattga ttctcctcct
     7741 gcaaaatcag ctgagttatc ttttggtagg taagattgac tagttgtaac tccccacttg
     7801 acagttcctt catagtcaat atctcccatg attgcacgaa ttaatgcagt cgtttgaata
     7861 tcattttgtc caataagtgc tgtcttatca tctggacgca agatgaaact aatattatcc
     7921 aagatagttt caccatcaat ctttacagtt agattttcta ctgtcaagag atcattacca
     7981 atctcacgtt ccgctttaaa gttgataaat ggatatttac gactagatgg tacaatctct
     8041 tctagctcaa tcttatcaag cattttctta cgtgatgttg cctgccttga cttagaagca
     8101 ttggcagaga aacgagcaac gaattcttgc aattgtttaa ttttttcttc tgctttagca
     8161 ttacggtctg ctagcaattt agcagcaagc tcagaagatt ccttccagaa gtcgtagttt
     8221 ccgacataga gtttgatttt tccaaagtca aggtcggcca tgtgagtaca aactttgttt
     8281 aagaagtgac ggtcgtggga tactacgata actgtgttat caaagtcaat caagaagtct
     8341 tctaaccaag taatcgattg gatatccaaa ccgttagtag gctcgtccaa gagaagaaca
     8401 tctggtttac caaaaagtgc tttggcgagg agaaccttta ctttttcacc gttggccaat
     8461 tcgctcatgt tttggtagtg taattcttct ggaatgttta ggttttgaag tagttgagag
     8521 gcttcactct ctgcttccca acctccaagt tcggcaaact ctccttcgag ttcggcagca
     8581 cgaaccccgt cctcgtctga gaaatcttcc ttcatgtaga tagcatcttt ctctttcatg
     8641 atgctataaa gtttttcatt tcccatgata acgacatcaa tggcacgttc atcttcgtag
     8701 tcaaagtgat tttgacgaag aacagagaga cgttcatctg gaccaagaga gatgtgacca
     8761 gtagtaggtt cgatatctcc agctaaaatt tttaaaaagg ttgattttcc ggcaccatta
     8821 gcaccgatta atccgtaagt atttccttct gtaaatttga tattgacatc atcaaaaagt
     8881 ttgcgatcac taaaacgtag tgaaacatca gatactgtaa gcaatatttt tctcctatat
     8941 gtgtaatata tttattctac tagaaaatac agaaatattc aaatttttat ttgtcaattt
     9001 tgtgtaaatt atatttacag tatcctttac acaaatctgt aaaaagcaag gctgatttat
     9061 tttgataaat tacggttatt tcattaaaaa aatgctataa ttgaaaggac tatatcgaag
     9121 gagaacaaaa tgactaaacc cattatttta acaggagacc gtccaacagg aaaattgcat
     9181 attggacatt atgttggaag tctcaaaaat cgagtattat tacaggaaga ggataagtat
     9241 gatatgtttg tgttcttggc tgaccaacaa gccttgacag atcatgccaa agatcctcaa
     9301 accattgtag agtctatcgg aaatgtggct ttggattatc ttgcagttgg attggatcca
     9361 aataagtcaa ctatttttat tcaaagccag attccagagt tggctgagtt gtctatgtat
     9421 tatatgaatc tagtttcgtt agcacgtttg gagcgaaatc caacagtcaa gacagagatt
     9481 tctcagaaag gatttggaga aagcattccg acaggattct tggtctatcc aatcgctcaa
     9541 gcagctgata tcacagcttt caaggctaat tatgttcctg ttgggacaga tcagaaacca
     9601 atgattgagc aaactcgtga aattgttcgt tcttttaaca atgcatataa ctgtgatgtc
     9661 ttggtagagc cggaaggtat ttatccagaa aatgagagag cagggcgttt gcctggttta
     9721 gatggaaatg ctaaaatgtc taaatcacta aataatggta tttatttagc tgatgatgcg
     9781 gatactttgc gtaaaaaagt aatgagtatg tatacagatc cagatcatat ccgcgttgag
     9841 gatccaggta agattgaggg aaatatggtt ttccattatc tagatgtttt tggtcgtcca
     9901 gaagatgctc aagaaattgc tgatatgaaa gaacgttatc aacgaggtgg tcttggtgat
     9961 gtgaagacca agcgttatct acttgaaata ttagaacgtg aactgggtcc tattcgtgag
    10021 cgccgtattg aatttgctaa ggatatggga gaagtttata atatgattca aaaaggtagt
    10081 gaaagagcgc gtgaagttgc gggtcaaacc ctatctgagg taaaaggggc aatgggactt
    10141 cattacttta actaagttta ttttacaaga aactatcatt tctatctcga agaaaagata
    10201 gttttttatt tacccctgta acatttgaca aatttttata gaatggtatg atagatacaa
    10261 tataaaaaga gtcaagctca aaaagaaaga aaagaggaaa cttcgaatgt ctaattggga
    10321 cactaaattt ttgaaaaaag gttttacctt tgatgatgta ttgcttattc cagctgaaag
    10381 tcatgtgttg cctaacgatg cagatttaac aactaaattg gcagataatt tgactttaaa
    10441 tatcccaatt attaccgctg ccatggacac agttacagag agtcaaatgg ccattgctat
    10501 tgctcgtgca ggtggtctcg gagttatcca taaaaacatg tcaattgctc aacaagcaga
    10561 cgaggttcgt aaggtaaaac gttctgaaaa tggagttatt attgatccgt tcttcttgac
    10621 gcctgaacat acaattgctg aagcagatga gcttatgggt cgttaccgca tcagtggtgt
    10681 tccagttgtt gaaacacttg aaaatcgtaa attggttggt attttgacaa accgagatct
    10741 tcgttttatt tcagattata atcaaccaat ttcaaaccat atgactagtg aaaatcttgt
    10801 tactgctcct gtgggtacgg atcttgcaac ggctgagagt attcttcaag agcatcgtat
    10861 tgaaaaactt ccgttggtcg atgaagaagg cagtctttct ggtttgatca ctatcaaaga
    10921 tattgaaaaa gttattgagt ttccaaatgc ggctaaagat gaatttggtc gtcttctagt
    10981 tgcaggtgca gtaggtgtta cttcagatac atttgaacgt gcagaggctc tttttgaggc
    11041 aggagcggat gcgattgtta ttgatactgc acatggtcat tctgcaggtg tcttgcgtaa
    11101 aattgccgag attcgtgctc atttcccaga tcggactttg attgctggaa atattgctac
    11161 tgctgaaggt gcacgtgccc tttatgaagc gggtgtagac gttgttaagg ttggtattgg
    11221 accaggttct atctgtacta ctcgtgtgat tgctggtgtt ggtgttccgc aagtaacagc
    11281 tatctacgat gctgcagctg ttgcgcgcga atatggtaaa acgattattg ctgacggtgg
    11341 gatcaagtat tctggagata ttgtaaaagc acttgctgca ggtggaaatg ctgttatgct
    11401 tggatctatg tttgctggaa ctgatgaagc tccaggcgaa actgaaatct tccaaggacg
    11461 taaattcaag acttaccgtg gtatgggatc aattgctgct atgaagaaag gttcaagcga
    11521 ccgttatttc caaggttctg tcaatgaagc aaacaagctc gttccagaag gaattgaagg
    11581 tcgtgttgct tataaaggag cggcagctga tattgttttc caaatgattg gtggtattcg
    11641 ctctggtatg ggttactgtg gtgcagctaa ccttaaagaa ctacacgata atgctcaatt
    11701 tattgaaatg tctggtgctg gtttgaaaga aagccatcct catgatgtgc aaattactaa
    11761 tgaggcacca aattattcta tgtaaaaaac aatgaaaaga actccagtga aaacaggagt
    11821 tcttttacaa tgttgtcaat ttccatttac agaagcttta ccatcctgaa tagtgaagat
    11881 acttagattt tctggcagat tttgaagatg gtctaagctt gttgttgtga taaaggtttg
    11941 gattgattga gaaatcgttt ctaataattt taactgtcta gtgttgtcaa gttcactcat
    12001 cacatcgtca agcagtaata taggagattc tgtggtaatg ctttccatta attcgatttc
    12061 tgctaatttt atcgagagga cgagactacg atgttgacct tggcttccga aactagcatc
    12121 catcccattt atataaaaag aaatgtcatc tcgatgagga ccgacaccag tattcttttt
    12181 aaataaatct ctggatctac ttttttctaa agcaattttg aaagattcgg ataagttttg
    12241 tttgtcagtt atattgacag aagattgata ggatattgac aactcttcga tctgattaga
    12301 gagttcaaaa tgtttcttac gcccaaatga ttctagtttt tttatgaaat ctaagcggtg
    12361 attcattaca cgacatccat aatcaactag ctgatcatct aacacagaaa ggaatgtttc
    12421 atctattttt tgagctgatt ttaggtaagt gtttctttgc tttaggatgt ggttataatt
    12481 ggttaagtca gataaataga ttggcttaat ttgcccaagt tccatatcaa tgaattttcg
    12541 tcgaatcgaa ggtgctcctt taattagttg taaatcttca ggagcaaata agacaacatt
    12601 catgtgtcct acataatctg aaaggcgtgc ctgttttaag tgattaactt ttgttacacg
    12661 gcctttttgt gttagttcga tttctagggg aatggatcca gtttttttct gaacgagacc
    12721 tgaaagatga agttgttcct catcaaaatg aatgagattt ttatctgttc gagttcgatg
    12781 actacgcgtt aaggctaaaa aatagatagc ctctaacatg tttgtttttc cttgtgcatt
    12841 acgtcccaaa aagacattca atttaggatt aaagtctatt ttcgtttctt tgtaattacg
    12901 aaaagtcttg agagatagat gttgtagcca catgattatc taccagggaa tcgtggagct
    12961 tgttggcttt taggtgatga agcaggtttc gatttgtctt ttttaactcc cttattcatc
    13021 tttttgacaa gtttagcgat ccgttctttt tcaactttat cagcttggta ttcatcttgt
    13081 tcttcagaag taggttgtgt caacaagatg tcaatgttca tgtcagggat gtcaacttta
    13141 tcgccaatac gaagtttttt tccacgacga ctctctaatt ccctattaaa gtaaacagaa
    13201 tgttcagaga gaaatgattt aatagctcct ccgctatgtg taattccaag ttctttgagt
    13261 agtgcttgga gggtaataaa ttcttcaaat aatttgtatt ccataattca cctcaatctt
    13321 tggtattata ccatattttc ctaaaaatag tgagagagac agcgagaaat gtaagcgatt
    13381 tttatttcaa aagtgttaca gggaacaaga aaatttcagg ttttcgtgat ataatagaag
    13441 tctgtatata aggaggtaaa tcatggagtt agtgcatgga atttcaacac attttatcca
    13501 atcaaaaaag tttaaaacaa acaaaattac cgtgcgtttt accgctccat tatcccttga
    13561 tacgattgca ggtcacatgt tgagtgcaag tatgctagag actgctaatc agatgtaccc
    13621 cacttctcaa gatttgagga gacacttggc cagtctatac ggtacagata tgtcaaccaa
    13681 ttgtttcaga agagggcaaa gccacattat agaattgaca tttacctatg ttcgtgatga
    13741 gtttttaagt aggaaaaacg tgctaacctc tcagattttg gaacttgtaa aagaaactct
    13801 tttttcaccc gcagtagttg ataatgggtt tgatccggcc ttatttgaaa ttgagaaaaa
    13861 acaattgcta gcaagtttag cagctgatat ggatgattct ttttattttg cacataaaga
    13921 attggataaa ttgttttttc atgatgaacg tcttcaattg gaatatagtg atttacgaaa
    13981 tcgtatttta gctgaaactc cacaaagttc ttattcttgt ttccaagaat ttttagccaa
    14041 tgatcgaata gatttctttt tcctaggtga ttttaatgag gttgaaattc aaaatgtatt
    14101 agaatcattt ggctttaaag gtcgaaaagg agatgtgaag gttcagtatt gtcaacctta
    14161 ttctaatatc cttcaggaag gtatggttcg gaaaaatgtg ggacaatcca ttttggaatt
    14221 aggttatcat taccgttcta aatatggtga tgagcaacat ttacccatga ttgtaatgaa
    14281 tggtttactt ggtggatttg ctcactctaa gctctttaca aatgtccgtg aaaatgctgg
    14341 attagcttat accatttcaa gtgagcttga tttatttagt ggattcttga ggatgtatgc
    14401 tggtatcaat cgagaaaatc gtaaccaggc tcgtaaaatg atgaataatc aactgcttga
    14461 tttaaaaaaa ggttatttta cagagtttga gttaaatcag accaaggaaa tgattcgttg
    14521 gtcgttgtta ctttctcaag ataatcaatc ttcattgatt gaacgtgctt atcaaaatgc
    14581 cttatttgga aaatcttcag cagactttaa aagttggatt gcaaagcttg aacaaattga
    14641 caaagatgct atttgtagag tagctaataa tgtgaaacta caagcgattt actttatgga
    14701 aggaatagaa tgacaaaggt tgtttttgaa gaaaaatact atccagctgt aaaagaaaag
    14761 gtttatcgaa ctcgtttggc caacggattg acagttgctc ttttgcctaa aaaggaattt
    14821 aaagaggttt acgggagtgt cactgtacag tttggttcgg tagatacgtt tgtcacagaa
    14881 gttgacggat atgtaaaaca atatcctgga ggaattgctc attttcttga acataaatta
    14941 tttgagagag aagattctag tgatttgatg tcggctttta cgagtctagg tgcagatagt
    15001 aatgccttta caagctttac aaaaacaaac tatctttttt cagcaacgga ttatttttta
    15061 gaaaatttag atttacttga tgaattggta acatcagcac actttactga agcttccatt
    15121 ctgacagagc aggatattat tcagcaagaa cgagaaatgt accaagatga tccagattcg
    15181 tgtttattct tttcaacttt agcgaatttg tatcctggta cacctttagc aactgatata
    15241 gttggaagtg aggagtccat ttcccaaatc aatctaacta atttgcaaga aaattttaca
    15301 aagttttaca aacctgtaaa catgtctctg tttttagttg gtaattttga tgtggagcga
    15361 gtacaggact attttgaaag caaagaactg aaagattcag attttcagga agtagcaaga
    15421 gaaaagttgt ttttacagcc tgtaaagcca acagatagta tgagaatgga agtatcttct
    15481 cccaaactag cgattggagt tagaggtaag cgagaagttt ctgaagcgga ttgctatcga
    15541 catcatattt tattaaaatt attgtttgca atgatgtttg gttggacttc ggatcgtttt
    15601 caaaaatgtt atgaatcagg taaaattgat gcgtccttat ctctggaagt tgaaataaca
    15661 agtcgctttc attttgtcat gttgacaata gatacgaaag agccagttgc tttgtctcat
    15721 caatttagga aggctattcg taattttaca aaggatttag atattacaga ggaacattta
    15781 gatattatca aaagagagat gtttggcgaa tttttcagta gcatgaactc tcttgaattt
    15841 attgcaacgc aatatgatgc ttttgaaaat ggtgagacaa tttttgattt gccgaaaatt
    15901 ttacaggaaa ttactttaga ggatgtcctt gatgctggac atcatttaat agatgatggt
    15961 gacatagttg attttacaat attcccatcg tagtaaccta tcataataga cactagaaag
    16021 aagggatgac aagtatgaga aaaaaaacaa ttggagaggt tttacgatta gctagaatca
    16081 atcagggatt gagtttagat gaattgcaga aaaagacaga aatccagtta gatatgttgg
    16141 aagcaatgga agcagacgat ttcgatcaac ttccaagtcc tttttacacg cgttctttct
    16201 tgaaaaaata tgcatgggct gttgagttag atgaccaaat tgttttggat gcttatgatt
    16261 ctgggagtat gattacttat gaggaagtag atgttgatga agatgagttg acaggtcgta
    16321 gacgttcaag taagaaaaag aagaaaaaaa catcattttt acctttattt tattttatcc
    16381 tttttgcttt atcgatttta atttttgtga cttattatgt ttggaactat attcaaactc
    16441 aaccagagga gccttctctt tctaattaca gtgtggttca atcaacaagt tcaactagct
    16501 ctgttcccca ctcctcaagt agtagttctt ctagtataga atcagctata agtgtatcag
    16561 gcgaaggaaa tcatgtagaa atcgcttata agacaagtaa ggaaacagtt aaattgcaat
    16621 tggcagtttc agatgttaca agttgggtca gtgtttcaga aagcgaactt gagggcggtg
    16681 taaccttatc gccaaagaag aaaagtgcag aagcaacagt tgcaactaaa agtcctgtaa
    16741 caattacgtt aggtgttgta aaaggtgttg atttgacagt agataatcag actgttgatt
    16801 tatcgaaatt aacagctcag actggacaaa tcactgtaac ctttactaaa aattaaggaa
    16861 aaacgaatga aaaaagaaca aattcccaat ctcttaacaa taggtcgaat tctctttata
    16921 cctattttta tctttatttt gacgatagga aattcgatag agagtcatat agttgcagct
    16981 attatctttg ctgttgccag tattaccgac tatttagatg gatatttagc tcgtaaatgg
    17041 aatgtggtca gtaattttgg taaatttgca gatcctatgg cggataagtt actagttatg
    17101 tcggctttta ttatgttgat tgagttaggt atggctccgg cttggattgt tgcagtgatt
    17161 atctgtcgtg agttagctgt gacaggttta aggcttttat tggttgaaac tggtggaaca
    17221 attttagcag cagcaatgcc tggaaaaatt aaaactttta gtcagatgtt tgctattatt
    17281 ttcttgctat tacattggac tttgcttggt caagttctac tttatgtagc cttatttttc
    17341 actatctact ctggctatga ctatttcaag ggtagtgcct atgtatttaa agggacattt
    17401 ggttcgaaat gaaatcaata attgatgtaa aaaatctttc ttttcgctat aaagaaaatc
    17461 agaactacta cgatgtgaag gatattacgt ttcacgtgaa acgtggagaa tggctttcga
    17521 ttgtagggca taatggtagt ggtaaatcaa cgacggttcg attaattgat ggcttactgg
    17581 aagcagaatc cggagagatt gtaattgatg gccaacgttt gactgaggaa aatgtttgga
    17641 atatacgtcg tcaaatcggt atggtttttc aaaatccaga caatcaattt gttggagcga
    17701 ctgttgaaga tgatgttgct tttggtttgg aaaatcaggg actttctcgt caagaaatga
    17761 aaaagagagt ggaagaagct ctggctttag ttggcatgtt ggactttaaa aagagagagc
    17821 cagcgcgtct atcaggtggc caaaagcaac gtgtggccat tgcaggtgtt gtagccctaa
    17881 gaccagctat tttaatctta gatgaagcaa cgagtatgtt ggatcctgag gggcgtagag
    17941 aacttattgg gacagtaaaa ggaattcgaa aagactatga tatgacggtc atttctatta
    18001 cccatgattt ggaagaagtc gccatgagtg atcgcgtatt ggtcatgaaa aaaggggaaa
    18061 ttgaatcaac tagtagtcca agggagcttt tctctcgaaa tgatttagat caaattggat
    18121 tagacgatcc ttttgctaat caattaaaaa aatctttgag ccagaatggc tatgatttac
    18181 ctgaaaatta tttgacagaa agtgagctag aggataagct atgggaattg ctctagaaaa
    18241 tgtgaatttt atatatcaag aaggtactcc cttagcttca gcagctttgt cggatgtttc
    18301 tttgacgatt gaagatggct cttatacagc tttaattggg cacacaggta gtggtaaatc
    18361 aactatttta caactcttaa atggtttatt ggtgccaagt caagggagtg tgagggtttt
    18421 tgatacctta atcacctcga cttctaaaaa taaagatatt cgtcaaatta gaaaacaggt
    18481 tggcttggta tttcagtttg ctgaaaatca gatttttgaa gaaacggttt tgaaggacgt
    18541 tgcttttgga ccgcaaaatt ttggagtttc tgaagaagat gctgtgaaga ctgcgcgtga
    18601 gaaactggct ctggttggaa ttgatgaatc actttttgat cgtagtccgt ttgagctgtc
    18661 agggggacaa atgagacgtg ttgccattgc aggcatactt gccatggagc catctatatt
    18721 agtcttagat gagccaacag ctggtctaga tcctctaggg agaaaagagt tgatgaccct
    18781 gttcaaaaaa ctccaccagt cagggatgac catcgtcttg gtaacgcatt tgatggatga
    18841 tgttgctgaa tatgctaatc aagtctatgt aatggaaaag ggacgtttag taaagggggg
    18901 caaaccaagt gatgtctttc aagacgttgt ttttatggaa gaagttcagt tgggagtacc
    18961 taaaattacg gccttttgta aacgattggc tgatagaggc gtgtcattta aacgattacc
    19021 gattaagata gaggagttca aggagtcgct aaatggatag tatgattttg gggcgttata
    19081 tcccagggga ttcgattgtt caccgattgg atccacgtag caaattgctt gctatgatgc
    19141 tactgatttt gattgtgttt tgggctaata accccttgac gaatctgatt ctttttatag
    19201 cgacagggat atttattgcc ttgtcaggag tatctctttc attttttatt cagggcttga
    19261 agtctatgtt tttcttgatt gccttcacaa ctatttttca actatttttc atttctaatg
    19321 ggaatgtttt atttgagttt tcgtttgtga gaatcacgga ttatgctttg caacaagctg
    19381 ggattatttt ttgtcgcttt gtattgatta ttttcttttc aactttgtta accttaacaa
    19441 ccatgccttt aagtttggca tcagctgtcg aagctttatt agcaccttta aagcgtgtga
    19501 aagttccagt tcatgaaatt ggattgatgc tgtctatgag tttgcgtttt gtcccaacct
    19561 tgatggatga tacgactcgg attatgaatg cacagaaagc tcgtggagtg gattttggag
    19621 aaggaagcat cgttcaaaaa gtaaaggcga tgattcccat tttgattcct ctttttgcga
    19681 caagtttaaa acgtgcagat tccttggcta tcgctatgga agcgcgtggc tatcagggtg
    19741 gaaaaggcag aagtcaatac cgacaattga aatggactct aaaggatacg ctgaccattc
    19801 ttgttattct cgtacttggt tgttgtttat ttttcttaaa atcttagtag ctttcaggaa
    19861 ttgataaaaa gttactgtaa cagtttttga tataaaggta gggatatgaa ccgttttaaa
    19921 aaatcaaaat atgtcattat tgtttttgtc actgttctgc ttgtgtcagc tctcttagcg
    19981 acgacttatt caagtacaat tgtgacaaaa ttaggagatg gaatctcatt ggttgataga
    20041 gttgtacaaa aaccttttca gtggtttgat tctgtcaaat cagatttggc tcatttgaca
    20101 cgaacatata atgaaaatga aagtttgaag aaacagcttt accaattaga agttaaatca
    20161 aatgaggtgg aaagtttaaa gacagaaaat gaacaactgc gccaattgct tgatatgaag
    20221 tctaaattgc aagccacaaa gactttagca gcagatgtta ttatgcgttc tccggtatct
    20281 tggaagcagg agttgacctt agatgcaggt agatcaaaag gtgcttctga gaacatgtta
    20341 gctattgcaa atggtggctt gattgggagt gtttcaaaag tagaggagaa ctctactata
    20401 gtcaaccttc tgacaaatac ggaaaatgct gataagattt ctgttaaaat tcaacatggc
    20461 tctactacaa tttatggaat tattattggc tatgacaagg aaaatgacgt tcttaaaatt
    20521 agccaattaa atagtaatag cgatattagt gcgggagata aggtgactac tggtggatta
    20581 ggaaacttta acgttgctga tattcctgtt ggtgaagtgg ttgccacaac gcatagtaca
    20641 gactatttga cacgagaagt aactgttaaa ttgagtgcag atactcataa tgtagatgtg
    20701 atagaattag tggggaattc ataatgagac agttgaagcg agttggagta tttttattgc
    20761 ttcctttctt tgttctaatt gacgcccata ttagccagct tctgggctca tttttccccc
    20821 atgtacattt ggctagtcat tttctttttc tatttctctt atttgagacg atagaagtat
    20881 cagagtatct ctacctagtc tattgttttg ttataggctt ggtttatgat gtttactttt
    20941 tccatctaat agggattaca actctcttat ttatcttatt gggagccttc cttcataaat
    21001 tgaatagtgt tattttgttg aatcgttgga caagaatgct agctatgatt gtgctgacat
    21061 tcctgtttga aatgggtatt tatcttttgg cttttatggt agggttgaca gtagatagca
    21121 tgtcgatttt tatagtctat agcttggtac cgacgatgat tttaaatttt ttatggatta
    21181 ctgtttttca atttattttt gaaaaatatt atctataaga acgacatata aatgtaacaa
    21241 aggcgtaata tttattaggc ctttttttgg tatactagta ttgtctttaa aagaaggagt
    21301 atctacgtaa tatgaagaaa aaaatcttag cgtcactttt attaagtaca gtaatggttt
    21361 ctcaagtagc tgttttaaca actgcgcatg cagaaacgac tgatgacaaa attgctgctc
    21421 aagataataa aattagtaac ttaacagcac aacaacaaga agcccaaaaa caagttgacc
    21481 aaattcagga gcaagtatca gctattcaag ctgagcagtc taacttgcaa gctgaaaatg
    21541 atagattaca agcagaatct aagaaactcg agggtgagat tacagaactt tctaaaaaca
    21601 ttgtttctcg taaccaatcg ttggaaaaac aagctcgtag tgctcaaaca aatggagccg
    21661 taactagcta tatcaatacc attgtaaact caaaatcaat tacagaagct atttcacgtg
    21721 ttgctgcaat gagtgaaatc gtatctgcaa acaacaaaat gttagaacaa caaaaggcag
    21781 ataaaaaagc tatttctgaa aaacaagtag caaataatga tgctatcaat actgtaattg
    21841 ctaatcaaca aaaattggct gatgatgctc aagcattgac tacgaaacag gcagaactaa
    21901 aagctgctga attaagtctt gctgctgaga aagcgacagc tgaaggggaa aaagcaagtc
    21961 tattagagca aaaagcagca gctgaggcag aggctcgtgc agctgcggta gcagaagcag
    22021 cttataaaga aaaacgagct agccaacaac aatcagtact tgcttcagca aacactaact
    22081 taacagctca agtgcaagca gtatctgaat ctgcagcagc acctgtccgt gcaaaagttc
    22141 gtccaacata cagtacaaac gcttcaagtt atccaattgg agaatgtaca tggggagtaa
    22201 aaacattggc accttgggct ggagactact ggggtaatgg agcacagtgg gctacaagtg
    22261 cagcagcagc aggtttccgt acaggttcaa cacctcaagt tggagcaatt gcatgttgga
    22321 atgatggtgg atatggtcac gtagcggttg ttacagctgt tgaatcaaca acacgtatcc
    22381 aagtatcaga atcaaattat gcaggtaatc gtacaattgg aaatcaccgt ggatggttca
    22441 atccaacaac aacttctgaa ggttttgtta catatattta tgcagattaa tttacagagg
    22501 gactcgaata gagccctctt ttcaggtttt accgtgacaa tccctattaa aaattatatc
    22561 aaaatagctt gaaaatattg gaaaagtatg gtaaaatgaa aattgtcgtg tgaacgataa
    22621 tactcattct tgatgaattg tgaagcagtt gcccttgggt cgttttgcga gttgaagtca
    22681 agaagaggaa aaaaacaaaa aggagaaata ctcatggcag taatttcaat gaaacaactt
    22741 cttgaggctg gtgtacactt tggtcaccaa actcgtcgct ggaatcctaa gatggctaag
    22801 tacatcttta ctgaacgtaa cggaatccac gttatcgact tgcaacaaac tgtaaaatac
    22861 gctgaccaag catacgactt catgcgtgat gcagcagcta acgatgcagt tgtattgttc
    22921 gttggtacta agaaacaagc agctgatgca gttgctgaag aagcagtacg ttcaggtcaa
    22981 tacttcatca accaccgttg gttgggtgga actcttacaa actggggaac aatccaaaaa
    23041 cgtatcgctc gtttgaaaga aattaaacgt atggaagaag atggaacttt cgaagttctt
    23101 cctaagaaag aagttgcact tcttaacaaa caacgtgcgc gtcttgaaaa attcttgggt
    23161 ggtatcgaag atatgcctcg tatcccagat gtgatgtacg tagttgaccc acataaagag
    23221 caaatcgctg ttaaagaagc taaaaaattg ggaatcccag ttgtagcgat ggttgacacc
    23281 aatactgatc cagatgatat cgatgtaatc atcccagcta acgatgacgc tatccgtgct
    23341 gttaaattga tcacagctaa attggctgac gctattatcg aaggacgtca aggtgaggat
    23401 gcagtagcag ttgaagcaga atttgcagct tcagaaactc aagcagattc aattgaagaa
    23461 atcgttgaag ttgtagaagg tgacaacaaa tagtaattac ctaggagggc ggggcttagc
    23521 ccggctctcc tattttcaaa aaatatagga gaattaaaat ggcagaaatt acagctaaac
    23581 ttgtaaaaga gttgcgtgaa aaatctggtg ccggtgttat ggacgctaaa aaagcgcttg
    23641 tagaaacaga cggtgacatc gaaaaagcga ttgaattgct tcgtgaaaaa ggtatggcta
    23701 aggcagctaa gaaagctgac cgtgttgctg cagaaggttt gactggtgtt tatgttaacg
    23761 gtaatgttgc agcagttatt gaagtaaacg ctgaaactga cttcgttgca aaaaacgctc
    23821 aattcgttga attggtaaat actacagcta aagtcattgc tgaaggaaaa cctgctaata
    23881 atgaagaagc tcttgctttg ataatgcctt caggtgaaac tcttgaagct gcatacgtat
    23941 ctgcaacagc aactatcgga gagaaaatct cattccgtcg ctttgcattg attgaaaaaa
    24001 cagacgcaca acactttgga gcataccaac ataacggtgg acgtatcggt gttatttcag
    24061 ttgttgaagg tggagacgaa gcacttgcta aacaattgtc aatgcacatc gcagcgatga
    24121 aaccaacagt tctttcttac aaagaattgg atgagcaatt cgttaaagat gagttggcac
    24181 aattgaatca cgttatcgac caagacaacg aaagccgtgc aatggttaat aaaccagctc
    24241 ttccacactt gaagtatgga tcaaaagctc aattaactga tgatgttatt gctcaagctg
    24301 aagctgacat caaagctgaa ttggctgcag aaggcaaacc agaaaaaatc tgggacaaaa
    24361 ttatcccagg taaaatggat cgcttcatgc ttgataatac taaagttgac caagcttaca
    24421 cacttcttgc acaagtttac atcatggatg acagcaagac agttgaagca taccttgaat
    24481 cagttaacgc ttcggtagtt gagtttgctc gctttgaagt tggtgaaggt atcgagaaag
    24541 ctgcaaacga cttcgaagct gaagttgcag ctacaatggc agcagccttg aataactaat
    24601 aatagaaagg aagcaaattg cttccttttt tgtatagggc ttagattttt cctgaaattg
    24661 ttttttcccc agtctcactc gattagaata attaaaacaa aaagccctat aataagggct
    24721 aagtgcattt aggagactat acttcaaatt catagtaagc gcgtcataac aaggtatcta
    24781 tcctaattcc ccaacttcca gtataccaga taaaaaataa ttatcggagg aaaggtattg
    24841 tactatgata attcaactaa gtgatttagg tcaagttcac cttgtttgtg gcaagacaga
    24901 tatgaggcag ggaatagact cattagccta tgtagttaaa acccactttg aattggatcc
    24961 tttctccgat caagtctttc tcttttgtgg tggacgtaaa gaccgcttta aagttcttta
    25021 ctgggatggt caaggatttt ggatattata taaacgcttt gagaacggaa aactgacttg
    25081 gtccagtaca gaaaaggatg tcaaagctct cacatctgaa caagtagatt ggctgatgaa
    25141 gggcttttct atcactcccc aaatatagtg gatttaaact agaatagtac acctctgctt
    25201 ctaaaacatt gttagaaatc gatttgacta tcctgttctt atttcatttt actataaatt
    25261 catcagaaag tcgtgatttc tattgaaatg aggactttct ttttatactc atctgttttc
    25321 aaaaagcatt ctagtccgtc tccgattaac gatggacttt atcacctcct tctccagtcc
    25381 ttgtatgaca tcttccaaag ttcgaaaggc tttattctta aatccacgtt tacgaatctc
    25441 tttccacact tgttcaatgg ggttcatctc tggtgtgtat ggaggaataa atgcaaagcc
    25501 aatattagtc ggaatcttta aggtacttga tttatgccat atagcattgt ccataacgag
    25561 taaaagataa tcatctggat aagcttgtga aagctcctat tcctaaagcc cctttagcgc
    25621 ataactttgg ctcagcttct attatcgctc acaccatcca tcagaagttt aatctgaagg
    25681 tacccaatta tcgccaagaa gaagattggg ctaggatggg tttaccaatc acacgtaagg
    25741 aaatctctaa ttggcatatc aagacgagtc aatactattt ggagcccctt tataacctct
    25801 tgcgagagag actattgact cagcccttac ttcatgcgga tgaaacttct tatagggtgc
    25861 tagagagtga tagtcagctg acttactatt ggactttttt gtctgggaaa gctgagaaac
    25921 aagggattac gctttaccat catgttctaa tcgatttgtt catatcttat ttcaatccat
    25981 tataaatagt gagaaatatc tatcctatct tctagaatgt cttccaaacg tggaaactct
    26041 cgtaaacaaa gaggttttag aggcctattt accatggact aaagttgtac aagaaaagtg
    26101 caaataagaa atctccagat taggaactat ccgtgagttc tctagtctgg agatttttca
    26161 atagacttcg ttattggacg gttacaattc ataaagtgct gtagagagat aacgttcacc
    26221 gttatctggt gctagggcaa ggactttttt acctgtacct aattttttgg caacctcgat
    26281 ggctccgtag atagctgcag ctgaggaaat ccctacaagg aagccttctt ttccaccaat
    26341 ttcacgtccg agtgcaagag cgtcatctga tgttacacga acgataccat cataggcttt
    26401 agtatcaagt gtatcaggaa taaatccagc tgagatacct tgaattttgt gaggaccagg
    26461 tttttcacca gatagaatag cagattcatc tgcttctact gcaaaaactt gaatgttaga
    26521 attttctgat ttgagtgcat gagaaacacc agaaatcgtt ccaccagtac ctactccagc
    26581 aacaaaggca tctaatccat ctttaccgaa agcagctagt atctcagctc ctgttgttct
    26641 ttcgtgtact tctggattag ctggattgtc aaattgaaga ggaaggaaac catcacgttc
    26701 agcagcgatt tcttgagcct tagcaatagc acctttcatt ccctcgctac caggagttag
    26761 gacgagttca gcaccataag cttggataat tttacgtcgt tctacactca tagtttcagg
    26821 cataacgatg acgactttat accctttagc agcacctacc catgaaagtc caataccggt
    26881 gtttccactt gttgcttcaa caatagtaga accaggtttc agaataccat cttgttcagc
    26941 tttttcaatc atgctaaggg caatacggtc ttttacagat gaaccaggat taaatgcttc
    27001 aagctttata tagacgtctg cagcaccttc tggcacgatg ttgttaagtt taacaatcgg
    27061 tgtttgaccg attaattcag taatgttgtt ataaatagac atatgaatac ctctttgtat
    27121 aagatatctt tagtataacg ctatccatac catttgtaaa atatagaaat cctatcgaag
    27181 cgataggatt tctatatatc atagatcaaa gtcattaatt ttcaagtgat tgcgttcagc
    27241 taattctagt aaataggtgt gaaggaaaac gatatcaggt ttcgtttgaa ttgcttcatt
    27301 ttctagtata ttttggtacg catcttttta ttttgctcgc taaagtagtt gtgagaatgt
    27361 caacgaaacg ctgtattatt cattgtttac actaagttta caggaacttc aacctctcgt
    27421 aaaccttggt cagttaaagt gacttttcca ttaaaaaact ccacaagtgc agctttaata
    27481 gtttcttttt cttctttatc aacataaatc atcgtatcga cttgatctgt aaagtttgta
    27541 tccagctcca tgagaccatg ttctttaagg aagttactgt actcttggta ctgagcataa
    27601 gacatttgaa tagcaatgcc agcctgttct tttatttcaa taataccaat ttctttgaca
    27661 gctaaggcga cactgccggc gtaagcacga attagtcctc cagcgcctag tttaatacca
    27721 ccaaagtagc gtgtcacgac cacacagaca ttggtgagat tgtgattttc tagtacccca
    27781 agcatgggaa caccagcagt accactaggc tcaccatcat cacttgtacg tttaatttca
    27841 ctacgttctc caataatgaa ggcagagcag ttatgtgtcg ctttgtagtg ttcttttttg
    27901 atggcagtaa tgaagtcacg agcctcttct tcgctataaa cacgcttggc atggcagata
    27961 aagcgagatt ttttgatttc ttcttggact tgaccgtcct ctttaattgt cctaaattcc
    28021 atgatttaat tgtactaaaa aatcatctaa agtgctagtt tttacgaata aagaagtatg
    28081 aaagtaaatt tagattatct cggtcgttta tttactgaga atgaattaac agaagaagaa
    28141 cgtcagttgg cggagaaact tccagcaatg agaaaggaga aggggaaact tttctgtcaa
    28201 cgctgtaata gtactattct agaagaatgg tatttgccca tcggtgctta ctattgtcga
    28261 gagtgcttgc tgatgaagcg agtcagaagt gatcaaactt tatactattt tccgcaggag
    28321 gattttccaa agcaagatgt tctcaaatgg cgcggccaat taactccttt tcaagagaag
    28381 gtgtcagagg gattgcttca agtagtagac aagcaaaagc caaccttagt tcatgcggta
    28441 acaggagctg gaaagacaga aatgatttat caagtagtgg ctaaagtgat caatgcgggt
    28501 ggtgcagtgt gtttggctag tcctcgcata gatgtttgtt tggagctgta caagcgcctg
    28561 caacaggatt tttcttgcgg gatagctttg ctacatggag aatcggaacc ttattttcga
    28621 acaccactag ttgttgcaac aacccatcag ttattgaagt tttatcaagc ttttgatttg
    28681 ctgatagtgg atgaagtaga tgcttttcct tatgttgata atcccatgct ttaccacgct
    28741 gtcaagaata gtgtaaagga gaatggattg agaatctttt taacagcgac ttcgaccaat
    28801 gagttagata aaaaggtccg tttaggagaa ctaaaaagac tgaatttacc gagacggttt
    28861 catggaaatc cgttgattat tccaaaacca atttggttat cggattttaa tcgctactta
    28921 gacaagaatc gtttgtcacc aaagttaaag tcctatattg agaagcagag aaagacagct
    28981 tatccgttac tcatttttgc ttcagaaatt aagaaagggg agcagttagc agaaatctta
    29041 caggagcaat ttccaaatga gaaaattggc tttgtatctt ctgtaacaga ggatcgatta
    29101 gagcaagtac aagcttttcg agatggagaa ctgacaatac ttatcagtac gacaatcttg
    29161 gagcgcggag ttaccttccc ttgtgtggat gttttcgtag tagaggccaa tcatcgtttg
    29221 tttaccaagt ctagtttgat tcagattggt ggacgagttg gacgaagcat ggatagaccg
    29281 acaggagatt tgcttttctt ccatgatggg ttaaatgctt caatcaagaa ggcgattaag
    29341 gaaattcaga tgatgaataa ggaggctggt ctatgaagtg cttgttatgt gggcagacta
    29401 tgaagactgt tttaactttt agtagtctct tacttctgag gaatgatgac tcttgtcttt
    29461 gttcagactg tgattctact tttgaaagaa ttggggaaga gaactgtcca aattgtatga
    29521 aaacagagtt gtcaacaaag tgtcaagatt gtcaactttg gtgtaaagaa ggagttgaag
    29581 tcagtcatag agcgattttt acttacaatc aagctatgaa ggattttttc agtcgctata
    29641 agtttgatgg agacttcctg ttaagaaaag ttttcgcttc atttttaagt gaggagttga
    29701 aaaagtacaa agagtatcaa tttgttgtaa ttcccctaag tcctgataga tatgctaata
    29761 gaggatttaa tcaggttgag ggcttggtag aggcagcagg ctttgagtat ctggatttat
    29821 tagagaaaag agaagagaga gccagttctt ctaaaaatcg ttcagagcgc ttggggacag
    29881 aacttccttt ctttattaaa agtggagtca ctattcctaa aaaaatccta cttatagatg
    29941 atatctatac tacaggagca actataaatc gtgttaagaa actgttggaa gaagctggtg
    30001 ctaaggatgt aaaaacattt tcccttgtaa gatgaggaaa aaatttgcaa aaatagaatg
    30061 aaagcgttat aataaaatca taaaaacaaa aatgtttaga aagaaggtac tcatatgatt
    30121 aaatatagta tccgtggtga aaacctagaa gtaacagaag caattcgtga ttatgtagtt
    30181 tctaaactcg aaaagatcga aaagtacttc caaccagaac aagagttgga tgcccgaatt
    30241 aacttaaaag tttatcgtga aaaaacggct aaagtggaag taacgattcc gcttggatct
    30301 attactctcc gcgcagaaga tgtatctcaa gatatgtatg gttcaattga ccttgtaact
    30361 gataaaattg aacgtcagat tcgtaaaaat aaaacaaaaa tcgagcgtaa aaataaaaat
    30421 aaggtagcaa ctggtcaatt atttacagat gctttggtgg aagattcaaa tgttgtccag
    30481 tctaaagttg ttcgttcaaa acaaattgat ttaaaaccaa tggatttgga agaagcaatt
    30541 ctacaaatgg atttattggg gcatgatttc tttatctatg tggatgttga agatcagaca
    30601 accaatgtga tttatcgtcg tgaggatggc gaaattggtt tgttagaggt taaagaatct
    30661 taatttcaat atgtgtaaag gtaggtttac tgaattgtaa actacctttt tcttataatt
    30721 gatagaatta ctgattacac ttttaaaaag tcgctttttg aggggtatta tggtataatg
    30781 ggtgccaaga ggttttgaat gaaaaaattt tatgtaagtc caatttttcc tattctagta
    30841 ggattgattg cgtttggagt cttatccact ttcattattt ttgttaataa taatctgttg
    30901 acggttttaa ttttgtttct ttttgtagga ggctatgttt ttttatttaa gaaactgaga
    30961 gtgcattata caaggagtga tgtagaacag atacagtatg taaaccacca agcggaagaa
    31021 agtttgacat ctctattgga acaaatgcct gtaggtgtta tgaaattgaa tttatcttct
    31081 ggagaggttg agtggtttaa tccctatgct gaattgattt tgaccaagga agatggtgat
    31141 tttgatttag aagctgttca aacgattatc aaggcttcag taggaaatcc gtctacttat
    31201 gccaagcttg gtgagaagcg ttatgctgtt catatggatg cttcttccgg tgttttgtat
    31261 tttgtagatg tatccaggga acaagccata acagatgaat tggtaacaag tcgaccagtg
    31321 attgggattg tctctgtgga taattatgat gatttggagg atgcaacttc tgagtcagat
    31381 attagtcaaa tcaatagttt tgtagctaat tttatatcag agttttcaga aaaatacatg
    31441 atgttttctc gtcgggtaag tatggatcga ttttatctat ttactgacta cacggtgctt
    31501 gagggcttga tgaatgataa attttctgtt attgatgctt tcagagaaga gtcgaaacag
    31561 agacagttgc ccttgacctt aagtatggga ttttcttatg gcgatggaaa tcatgatgag
    31621 atagggaaag ttgctttgct caatttgaac ttggctgaag tacgtggtgg cgaccaggtg
    31681 gttgttaagg aaaacgacga aacgaaaaat ccagtttatt ttggtggtgg gtctgctgct
    31741 tcaatcaagc gtacacggac tcgtacgcgc gctatgatga cagctatttc agataagatt
    31801 cggagtgtag atcaggtttt tgtagtcggt cacaaaaatt tagacatgga tgctttgggc
    31861 tctgctgtag gtatgcagtt gttcgccagc aatgtgattg aaaatagcta tgctctttat
    31921 gatgaagaac aaatgtctcc agatattgaa cgagctgttt cattcataga aaaagaagga
    31981 gttacgaagt tgttgtctgt taaggatgca atggggatgg tgaccaatcg ttctttgttg
    32041 attcttgtag accattcaaa gacagcctta acattatcaa aagaatttta tgatttattt
    32101 acccaaacca ttgttattga ccaccataga agggatcagg attttccaga taatgcggtt
    32161 attacttata tcgaaagtgg tgcaagtagt gccagtgagt tggtaacgga attgattcag
    32221 ttccagaatt ctaagaaaaa tcgtttgagt cgtatgcaag caagtgtctt gatggctggt
    32281 atgatgttgg atactaaaaa tttcacctcg cgagtaacta gtcggacatt tgatgttgct
    32341 agctatctca gaacgcgcgg aagtgatagt attgctatcc aggaaatcgc tgcgacagat
    32401 tttgaagaat atcgtgaggt caatgaactt attttacagg ggcgtaaatt aggttcagat
    32461 gtactaatag cagaggctaa ggacacgaaa tgctatgata cagttgttat tagtaaggca
    32521 gcagatgcca tgttagccat gtcaggtatt gaagcgagtt ttgttcttgc gaagaataca
    32581 caaggattta tctctatctc agctcgaagt cgtagtaaac tgaatgtaca acggattatg
    32641 gaagagttag gcggtggagg ccactttaat ttggcagcag ctcaaattaa agatgtaacc
    32701 ttgtcagaag caggtgaaaa actgacagaa attgtattaa atgaaataaa ggaaaaggag
    32761 aaagaagaat gaaagtaatc tttttagcag atgttaaagg aaaaggtaaa aaaggcgaaa
    32821 ttaaggaagt accaacaggg tatgcgcaaa actttcttat caaaaagaat ctagccaaag
    32881 aagcgactgc tcaagctgta ggtgaacttc gtggtaaaca aaaatcggaa gaaaaagctc
    32941 acgctgagat gattgcagaa ggaaaagcaa ttaaagcaca acttgaagca gaagaaactg
    33001 ttgtagaatt tgttgaaaaa gttggtccag atggtcgtac ctttggttct attaccaata
    33061 agaagattgc agaagaattg caaaagcaat ttggaattaa gattgataaa cgtcatattc
    33121 aagtacaagc tccgattcga gcggttggtt tgattgatgt gccagtgaaa atctatcaag
    33181 atatcacaag tgtaatcaat cttcgtgtga aagaaggata agtttacacc ttcttgacaa
    33241 gattgtaaaa ggaagggaag tctgatggca gaagtagaag agttacgagt acaacctcaa
    33301 gatatcttag ctgagcaatc cgttttaggg gctatcttta ttgatgagag taaacttgtt
    33361 tttgtgcgag aatacattga gtctcgggac ttttttaagt atgcccatcg tttgattttc
    33421 caagccatgg tcgatttatc cgatcgtggt gatgccatag atgcaacaac ggttcgtact
    33481 atccttgata atcaaggtga tttacagaat attggtggct tgtcttactt ggttgagatt
    33541 gttaattctg tgccaacttc tgctaatgcg gagtattatg ctaagattgt tgcagaaaaa
    33601 gcaatgctac gtcgtttaat tgccaagttg acagagtctg tcaaccaagc ttacgaagcg
    33661 tcacaaccag ctgatgaaat tattgctcag gcagaaaaag ggttgattga tgtcagtgaa
    33721 aatgcaaatc gaagcgggtt taagaacatt cgagatgtgt tgaatctcaa ctttggaaat
    33781 ctggaagctc gctcgcaaca aacgaccgat attacaggta ttgcgacagg ttatcgtgat
    33841 ttggatcata tgacaacagg acttcatgag gaggagttga ttatcttagc agctcgtcca
    33901 gcagttggta agacagcatt tgccttgaat atcgctcaga atattgggac taagttggac
    33961 aaaacggttg ctattttttc actcgaaatg ggtgcggaaa gcttggtaga ccgtatgtta
    34021 gctgcagaag gcttggtgga gtcacattct atccgtacag ggcaattgac agatgaggag
    34081 tggcaaaaat atactattgc tcagggtaat ctagctaacg ccagtatcta tatcgatgat
    34141 acgccaggta ttcggattac agagattcgt tctcgttctc gtaaattggc tcaagaaact
    34201 ggaaatcttg gtttgatttt gatagactat ttgcaactta tcacgggaac tggtcgagaa
    34261 aatcgtcaac aagaagtttc tgaaatttct cgtcagttga aaatactagc caaggaattg
    34321 aaggttccag taatcgctct gagtcagctt tctcgtggtg tagaacaacg tcaggacaag
    34381 agaccggtct tgtctgatat tcgtgaatct gggtctattg agcaggacgc tgatatcgta
    34441 gcttttctct atcgcgatga ctactatgaa cgtggtggtg aagaagagga gggtatccca
    34501 aataataagg tggaagttat tatcgagaaa aaccgtagtg gagctcgtgg aacagtggaa
    34561 ttgattttcc aaaaagaata caataaattt tcaagtatct caaagaggga ggcataagat
    34621 gtcagatgca tttacagatg tagccaagat gaaaaaaatc aaagaagaaa tcaaggcaca
    34681 tgagggacaa gtcgtagaaa tgactttgga gaatggtcgt aagcgccaaa aaaatagatt
    34741 gggtaagcta attgaagttt atccatccct atttattgtg gagtttgggg atgtggaagg
    34801 agataaacaa gttaatgttt acgttgaatc ctttacttac tcagatattc ttacagaaaa
    34861 gaatttgatt cattatcttg actaaagtga gaaattttct cactttttct tttttctccg
    34921 aataatttag gtgaaggcaa tcatcgcttt atattatttt ttaaggagga agaatgaaaa
    34981 ttttaccgtt tatagcaaga ggaacaagtt attacttgaa gatgtcagtt aaaaagcttg
    35041 ttcctttttt agtagtagga ttgatgctag cagctggtga tagtgtctat gcctattcca
    35101 gaggaaatgg atcgattgcg cgtggggatg attatcctgc ttattataaa aatgggagcc
    35161 aggagattga tcagtggcgc atgtattctc gtcagtgtac ttcttttgta gcctttcgtt
    35221 tgagtaatgt caatggtttt gaaattccgg cagcttatgg aaatgcgaat gaatggggac
    35281 atcgtgctcg tcgggaaggt tatcgtgtag ataatacacc gacgattggt tccattactt
    35341 ggtctactgc aggaacttat ggtcatgttg cctgggtgtc aaatgtaatg ggagatcaga
    35401 ttgagattga ggaatataac tatggttata cagaatccta taataaacga attataaaag
    35461 caaacacgat gacaggattt attcatttta aagatttgga tggtggcagt gttgggaata
    35521 gtcaatcctc aacttcaaca ggcggaactc attattttaa gaccaagtct gctattaaaa
    35581 ctgaacccct agttagtgca actgtgattg attactatta tcctggagag aaggttcatt
    35641 atgatcaaat tctcgaaaaa gacggctaca agtggttgag ttatactgcc tataatggaa
    35701 gctatcgtta tgttcaattg gaggctgtga ataaaaatcc tctaggtaat tctgttcttt
    35761 cttcaacagg tggaactcat tattttaaga ccaagtctgc tatcaaaact gaacccctag
    35821 ttagtgcaac tgtgattgat tactattatc ctggggagaa ggttcattat gatcagatac
    35881 ttgaaaaaga cggctacaag tggttgagtt atacggctta taacggaagt cgtcgctata
    35941 tacagctaga gggagtgact tcttcacaaa attatcagaa tcaatcagga aatatctcta
    36001 gctatggatc caataatagt tcaactgtcg gttggaagaa aataaatggt agttggtatc
    36061 atttcaaatc aaatggttct aaatcaacag gatggctgaa agatggttct agctggtatt
    36121 atttgaaatt atctggtgaa atgcagacag gatggttaaa ggagaatggc tcgtggtatt
    36181 atctgggtag ttcaggggca atgaaaacag gctggtacca ggtctctggt aagtggtatt
    36241 attcttactc ttcaggcgcc ttagctgtta atacgacggt ggatggctac agagtaaaca
    36301 gtgatggaga acgagtatag aaaattggag taggagaaat ttcctgctct tttctgtaag
    36361 cagtttcctt gacatttttc ttattttgcg ctatcatata tacatataat atatgggagt
    36421 ctgtgtacag tctgagagga agtgttaaac ttcgaccgca cctgatctgg gtaatgccag
    36481 cggagggaac gatacttagt ctaattttgc accttttcca tgtatggtaa aggtttttct
    36541 ttttttaaaa aggaaaacga gaagaggagg ttcttatgaa agcaagcatt gccttgcaag
    36601 ttttacccct agcacagggg attgatcgga tagctgttat tgatcaggtc attgcttatc
    36661 tgcaaactca agaagtgacg atggtagtga caccatttga aacggtcttg gaaggggagt
    36721 ttgatgagct tatgcgcatt ctaaaagaag cgctggaagt ggcagggcag ggggcagaca
    36781 atgtcttttc caatgtcaaa ataaatgtag gagagatttt aagtattgat gagaaacttg
    36841 agaagtatac tgagacgaca cattagtcta ttgggctttc tcggagtctt gtcaatctgg
    36901 cagttagcag gttttcttaa acttctcccc aagtttatcc tgccgacacc tcttgaaatt
    36961 ctccagccct ttgttcgtga cagagaattt ctctggcacc atagctgggc gaccttgaga
    37021 gtggctttac tggggctgat tttgggagtt ttgattgcct gtcttatggc tgtactcatg
    37081 gatagtttga cttggttcaa tgacctgatt taccctatga tggtggtcat tcagaccatt
    37141 ccgaccattg ccatagctcc tatcctggtc ttgtggctag gttatgggat tttgcccaag
    37201 attgtcttga ttatcttaac aacaaccttt cccatcatcg ttagtatttt ggacggtttt
    37261 aggcattgtg acaaggatat gctgaccttg tttagtctga tgcgagcaaa cccttggcaa
    37321 atcctgtggc attttaaaat cccggttagc ctgccttact tttatgcagg tctgagggtc
    37381 agtgtctcct acgcctttat cacaactgtg gtatctgagt ggttgggagg ttttgagggg
    37441 cttggtgttt atatgattca gtccaagaaa ttgtttcagt atgataccat gtttgccatt
    37501 attattctgg tgtcgattat cagtcttttg ggtatgaagc tggtcgatat cagtgaaaaa
    37561 tatgtgatta aatggaaacg tacttaaaat agagcgtttt tgaaaaagaa aagaggaaat
    37621 caaaatgaag aaaacatgga aagtgttttt aacgcttgta acagctcttg tagctgttgt
    37681 gcttgtggcc tgtggtcaag gaactgcttc taaagacaac aaagaggcag aacttaagaa
    37741 ggttgacttt atcctagact ggacaccaaa taccaaccac acagggcttt atgttgccaa
    37801 ggaaaaaggt tatttcaaag aagctggagt ggatgttgat ttgaaattgc caccagaaga
    37861 aagttcttct gacttggtta tcaacggaaa ggcaccattt gcagtgtatt tccaagacta
    37921 catggctaag aaattggaaa aaggagcagg aatcactgcc gttgcagcta ttgttgaaca
    37981 caatacatca ggaatcatct ctcgtaaatc tgataatgta agcagtccaa aagacttggt
    38041 tggtaagaaa tatgggacat ggaatgaccc aactgaactt gctatgttga aaaccttggt
    38101 agaatctcaa ggtggagact ttgagaaggt tgaaaaagta ccaaataacg actcaaactc
    38161 aatcacaccg attgccaatg gcgtctttga tactgcttgg atttactacg gttgggatgg
    38221 tatccttgct aaatctcaag gtgtagatgc taacttcatg tacttgaaag actatgtcaa
    38281 ggagtttgac tactattcac cagttatcat cgcaaacaac gactatctga aagataacaa
    38341 agaagaagct cgcaaagtca tccaagccat caaaaaaggc taccaatatg ctatggaaca
    38401 tccagaagaa gctgcagata ttctcatcaa gaatgcacct gaactcaagg aaaaacgtga
    38461 ctttgtcatc gaatctcaaa aatacttgtc aaaagaatac gcaagcgaca aggaaaaatg
    38521 gggtcaattt gacgcagctc gctggaatgc tttctacaaa tgggataaag aaaatggtat
    38581 ccttaaagaa gacttgacag acaaaggctt caccaatgaa tttgtgaaat aatgacagaa
    38641 attagactag agcacgtcag ttatgcctat ggtcaggaga ggattttaga ggatatcaac
    38701 ctacaggtga cttcaggcga agtggtttcc atcctaggcc caagtggtgt tggaaagacc
    38761 accctcttta atctaatcgc tgggatttta gaagttcagt cagggagaat tgtccttgat
    38821 ggtgaagaaa atccccaggg gcgcgtgagt tatatgttgc aaaaggatct gctcttggag
    38881 cacaagacgg tgcttggaaa tatcattctg cccctcttga ttcaaaaggt ggataaggca
    38941 gaagctattt cccgagcgga taaaattctt gcgaccttcc agctgacagc tgtaagagac
    39001 aagtatcctc atgaacttag cggtgggatg cgccagcgtg tagccttact ccggacctac
    39061 ctttttgggc acaagctctt tctcttagat gaggccttta gcgccttgga tgagatgaca
    39121 aagatggaac tccacgcttg gtaccttgag attcacaagc agttgcagct aacaaccttg
    39181 attattactc acagtatcga ggaggccctc aatctcagtg accgcatcta tatcttgaaa
    39241 aatcgccctg ggcagattgt ttcagaaatt aaactagatt ggtctgaaga tgaggacaag
    39301 gaagttcaaa agattgccta caaacgtcaa atcttggcag aattaggctt agataagtag
    39361 aaaaataggg agttggtgaa gattatcctt taccagcgcc ctttttcttt taaaaatgag
    39421 aaaatttcgg tataatagtc aaacaaggtc aaggtttaaa gagagaggtg ggtttgttat
    39481 gagatttaaa aatacatcgg atcatattga ggcctacatc aaggcgattt tagatcaatc
    39541 tggtatcgtg gagttgcaac ggagtcagtt ggcagatacc tttcaggttg ttcctagtca
    39601 gattaactac gtgatcaaga cacgctttac ggaaagtaga ggctacttgg ttgaaagtaa
    39661 gcgtggtggc ggaggctaca ttcgtatagg acggattgag ttttctagtc atcatgaaat
    39721 gctccgggag ctgctttact cgattggtga gcgagtcagt caagaaattt atgaggatat
    39781 tctccagctt ttggttgagc aggaattgat gaccaagcag gagatgaatt tgctagaatc
    39841 agtagctttg gatcgcgttt taggagaaga agctccagtt gttcgagcaa acatgctacg
    39901 tcagatcata caagaggtag atagaaaagg gaagtaagat gaactattca aaagcattga
    39961 atgaatgtat cgaaagtgcc tacatggttg ctggacattt tggagctcgt tatctagagt
    40021 cgtggcactt gttgattgcc atgtctaatc acagttatag tgtagcaggg gcaactttaa
    40081 atgattatcc gtatgagatg gaccgtttag aagaggtggc tttggaactg actgaaacgg
    40141 actatagcca ggatgaaacc tttacggaat tgccgttctc ccgtcgtttg caggttcttt
    40201 ttgacgaagc agagtatgta gcgtcagtgg tccatgctaa ggtgctaggg acagagcacg
    40261 tcttctatgc gattttgcat gatggcaatg ccttggcaac tcgtatcttg gagagggctg
    40321 gtttttctta tgaagacaag aaagatcagg tcaagattgc tacccttcgt cgaaatttag
    40381 aagaacgtgc aggctggact cgtgaagatc tcaaggcttt acgccaacgc catcgtacag
    40441 tagctgacaa gcaaaattct atggccaata tgatgggcat gccgcagact cctagtggtg
    40501 gtctcgagga ctatacgcat gatttgacag agcaagcgcg ttctggcaag ttagaaccag
    40561 tcatcggtcg ggacaaggaa atctcacgta tgattcaaat attgagccgt aagactaaga
    40621 acaaccctgt cttggttggg gatgctggtg tcgggaaaac agctctggcc cttggtcttg
    40681 ctcagcgtat tgctagtggt gacgtgcctg cggaaatggc taagatgcgc gtgttagaac
    40741 ttgatttgat gaatgtcgtt gcagggacac gcttccgtgg tgactttgaa gaacgcatga
    40801 ataatatcat caaggatatt gaagaagatg gccaagtcat cctctttatc gatgaactcc
    40861 acaccatcat gggttctggt agcgggattg attcgactct ggatgcggcc aatatcttga
    40921 aaccagcctt ggcgcgtgga actttgagaa cggttggtgc caccactcag gaagaatatc
    40981 aaaaacatat cgaaaaagat gcggctcttt ctcgtcgttt cgctaaagtg acgattgaag
    41041 aaccaagtgt ggcagatagt atgactattt tacaaggttt gaaggcgact tatgagaaac
    41101 atcaccgtgt acaaatcaca gatgaagcgg ttgaaacagc ggttaagatg gctcatcgtt
    41161 atttaaccag tcgtcacttg ccagactctg ctatcgacct cttggacgaa gcagcagcaa
    41221 cagtgcaaaa taaggcaaag tatgtaaaag cagacgattc agatttgagt ccagctgaca
    41281 aggccctgat ggatggcaag tggaaacagg cagcccagct aatcgcaaaa gaagaggaag
    41341 tacctgtcta caaagacttg gtgacagagt ctgatatttt gaccaccttg agtcgcttgt
    41401 caggaatccc agttcaaaaa ctgactcaga ctgacgctaa gaaatatcta aatcttgaag
    41461 cagaactcca taaacgggtt atcggtcaag atcaagctgt ttcaagtatt agtcgtgcga
    41521 ttcgccgtaa tcagtcagga attcgcagtc acaagcgtcc gatcggttcc tttatgttcc
    41581 taggacccac aggtgtcggt aagaccgagt tggccaaggc tttggcagaa gttctctttg
    41641 atgacgaatc agcccttatc cgctttgata tgagtgagta tatggagaaa ttcgcagcca
    41701 gccgtctaaa tggagctcct ccaggctatg tgggttacga agaaggtggg gagttgacag
    41761 agaaggttcg caataaaccc tattccgttc tcctctttga tgaggtagag aaggctcacc
    41821 cagatatctt taatgttctc ttgcaggttc tggatgacgg tgtcttgaca gatagcaagg
    41881 gacgcaaggt cgatttttca aataccatta tcattatgac atcgaaccta ggtgcgactg
    41941 cccttcgtga tgataagact gttggttttg gggctaagga tattcgtttt gaccaggaaa
    42001 atatggaaaa acgcatgttt gaagaactga aaaaagctta tagaccggaa ttcatcaacc
    42061 gtattgatga gaaggtggtc ttccatagcc tatctagtga ccatatgcag gaagtggtga
    42121 agattatggt caagccttta gtggcaagtt tggctgaaaa aggcattgac ttgaaattac
    42181 aagcttcagc tctgaaattg ttagcaaatc aaggatatga cccagagatg ggagctcgcc
    42241 cacttcgcag aaccctgcaa acagaagtgg aggacaagtt ggcagaactt cttctcaagg
    42301 gagatttagt ggcaggcagc acacttaaga ttggtgtcaa agcaggccag ttaaaatttg
    42361 atattgcata aaagaataaa agtaccagca tctgaccata agtcacagtg gagtgaaact
    42421 caatgaaaat caaagagcaa actaggcagc tagccgcagg ttgctcaaaa cactggtttg
    42481 aggttgcaga tagagctgac gtggtttgaa gagattttcg aagagtataa gctgcaagat
    42541 gaatgatttt cttgtattga cgttgttgtt gacaaaaagt agcggataaa tgaaatccat
    42601 tccattatca tagatgatag gctggtagga aattttcaaa tagcatacag gaaatagatg
    42661 tatggagttc tggtagtaga aagggagaga gatgaacatt ttagttgcag atgacgagga
    42721 aatgattaga gaaggaattg cagcatttct gacagaagag ggttatcatg tcattatggc
    42781 taaggatgga caagaggtct tggaaaaatt tcaagatctc cctatccatc tcatggtact
    42841 ggatttaatg atgcctagga agagtggttt tgaagtgtta aaagaaatca atcaaaagca
    42901 cgatattcct gtcatcgtct tgagtgctct gggagatgaa actactcagt cacaggtatt
    42961 tgatctctat gctgatgatc atgtgacaaa acctttttct ttggtactgc ttgtcaagcg
    43021 tattaaggcg cttatcagac gttactacgt catagaggat ctttggcgat atcaggatgt
    43081 aacagtggat tttacctctt acaaagcaca ttataaaaat gaagaaattg atctcaaacc
    43141 aaaggaatta ctggtactaa agtgtttgat tcagcataaa aatcaagttt taagtagaga
    43201 gcagatattg gaagaaattt caaaagatgt agctgattta ccttgtgata gggtcgttga
    43261 tgtctatatt cgtactcttc gcaaaaaatt agctttagat tgtatcgtga ctgtgaaaaa
    43321 tgttgggtat aagattagct tatgataaaa aatcctaaat tattaaccaa gtctttttta
    43381 agaagttttg caattctagg tggtgttggt ctagtcattc atatagctat ttatttgacc
    43441 tttccttttt attatattca actggagggg gaaaagttta atgagagcgc aagagtgttt
    43501 acggagtatt taaagactaa gacatctgat gaaattccaa gcttactcca gtcttattca
    43561 aagtccttga ccatatctgc tcaccttaaa agagatattg tagataagcg gctccctctt
    43621 gtgcatgact tggatattaa agatggaaag ctatcaaatt atatcgtgat gttagatatg
    43681 tctgttagta cagcagatgg taaacaggta accgtgcaat ttgttcacgg ggtggatgtc
    43741 tacaaagaag caaagaatat tttgcttttg tatctcccat atacattttt ggttacaatt
    43801 gctttttcct ttgttttttc ttatttttat actaaacgct tgctcaatcc tcttttttac
    43861 atttcagaag tgactagtaa aatgcaagat ttggatgaca atattcgttt tgatgaaagt
    43921 aggaaagatg aagttggtga agttggaaaa cagattaatg gtatgtatga gcacttgttg
    43981 aaggttattc atgagttgga aagtcgtaat gagcaaattg taaaattgca aaatcaaaag
    44041 gtttcctttg tccgcggagc atcacatgag ttgaaaaccc ctttagccag tcttagaatt
    44101 atcctagaga atatgcagca taatattgga gattacaaag atcatccaaa atatattgca
    44161 aagagtataa ataagattga ccagatgagc cacttattgg aagaagtact ggagtcttct
    44221 aaattccaag agtggacaga gtgtcgtgag accttgactg ttaagccagt tttagtagat
    44281 attttatcac gttatcaaga attagctcat tcaataggtg ttacaattga aaatcaattg
    44341 acagatgcta ccagggtcgt catgagtctt agggcattgg ataaggtttt gacaaacctg
    44401 attagtaatg caattaaata ttcagataaa aatgggcgtg taatcatatc cgagcaagat
    44461 ggctatctct ctatcaaaaa tacatgtgcg cctctaagtg accaagaact agaacattta
    44521 tttgatatat tctatcattc tcaaatcgtg acagataagg atgaaagttc cggtttgggt
    44581 ctttacattg tgaataatat tttagaaagc tatcaaatgg attatagttt tctcccttat
    44641 gaacacggta tggaatttaa gattagcttg tagacagatt agttttttat taaagttcac
    44701 atagggttaa cataagtgta ttattcttta tatagataaa aatatagata aaagaaagga
    44761 tactaatatg gtattagcga ttattttagt aatattcctt attcgattga tttttttaaa
    44821 gcgttcgata gagaatgaga aacgaatcct tagcaatggc gggaaagaat ttggagttga
    44881 gaatacaaaa cgattaacgt tggctcatat tgttttttat ctctcttgcc tcgttgaagc
    44941 aatggtgcat aagacaatgt ttgatggtat gagcatggtt ggtttagtct tgcttatttt
    45001 ttctatgctg atgttgatgt tggtgattca cttgttggga gatatttgga cagtgaagct
    45061 tatgcttgtc aataatcaca aatatgtaga tcatatctta tttaggacag taaaacatcc
    45121 taattacttt ttaaatatcc ttcctgagtt gattggcttg accttgttga gtcatgccta
    45181 tatgactttt gttttagttt ttccagttta tgcagttatt ttgtatcgac gaatagctga
    45241 agaggaaaag ctattacatg aagttataat cccaaatgga agcataaaga gataaataca
    45301 aaattcgatt tatatacagt tcatattgaa gtgatatagt aaggttaaag aaaaaatata
    45361 gaaggaaata aacatgtttg catcaaaaag cgaaagaaaa gtacattatt caattcgtaa
    45421 atttagtatt ggagtagcta gtgtagctgt tgccagtctt gttatgggaa gtgtggttca
    45481 tgcgacagag aaggaggtaa ctacccaagt acccacttat tctaatatgg caaagacaga
    45541 acataggaaa gctgctaaac aagtcgtcga tgaatatata gaaaaaatgt tgagggagat
    45601 tcaattagat agaagaaaac atacccaaaa tttcgccttc aacatgaagt tgagcgcaat
    45661 taaaacggag tatttgtatg gattaaaaga gaagtcggaa gctgagttgc cgtcagaagt
    45721 aaaagcaaag ttagacgcag cttttgagca gtttaaaaaa gatacattga aactaggaga
    45781 aaaggtagca gaagctgaga agaaggttgc agaagctgag aaaaaagcca aggctcaaaa
    45841 agaagaagat cgccgtaact acccaaccat tacttacaaa acgcttgacc ttgaaattgc
    45901 tgagtccgat gtggaagtta aaaaagcgga gcttgaacta ttgaaagagg aagctaaaac
    45961 tcgaaacaag gacacaatta agcaagcaaa agcgaaagtt gagagtaaac aagctgaggc
    46021 tacaaggtta gaaaaaatca agacagatcg taaaaaagca gaagaagaag ctaaacgaaa
    46081 agcagcagaa gaagataaag ttaaagataa actaaagagg cggacaaaac gagcagttcc
    46141 tggagagcca gcaacacctg ataaaaaaga aaatggtgcg aagtcttcag attctagcgt
    46201 aggtgaagaa actcttccaa gcccatccct gaaaccagaa aaaaaggttg cagaagctga
    46261 gaagaaggtt gcagaagctg agaaaaaagc caaggatcaa aaagaagaag atcgccgtaa
    46321 ctacccaacc aatacttaca aaacgcttga acttgaaatt gctgagtccg atgtgaaagt
    46381 taaagaagcg gagcttgaac tagtaaaaga ggaagctaag gaatctcgaa acgaggaaaa
    46441 agttaagcaa gcaaaagcga aagttgagag taaacaagct gaggctacaa ggttagaaaa
    46501 aatcaagaca gatcgtaaaa aagcagaaga agaagctaaa cgaaaagcag cagaagaaga
    46561 taaagttaaa gaaaaaccag ctgaacaacc acaaccagcg ccggctcctc aaccagaaaa
    46621 accagctcca gctccaaaac cagagaatcc agctgaacaa ccaaaagcag aaaaaccagc
    46681 tgatcaacaa gctgaagaag actatgctcg tagatcagaa gaagaatata atcgcttgac
    46741 tcaacagcaa ccgccaaaaa ctgaaaaacc agcacaacca tctactccaa aaacaggctg
    46801 gaaacaagaa aacggtatgt ggtacttcta caatactgat ggttcaatgg cgacaggatg
    46861 gctccaaaac aatggctcat ggtactacct caacagcaat ggcgctatgg cgacaggatg
    46921 gctccaaaac aatggttcat ggtactatct aaacgctaat ggttcaatgg caacaggatg
    46981 gctccaaaac aatggttcat ggtactacct caacgctaat ggttcaatgg cgacaggatg
    47041 gctccaatac aatggttcat ggtactacct caacgctaat ggtgatatgg cgacaggatg
    47101 gctccaaaac aatggctcat ggtactacct aaacgctaat ggtgatatgg cgacaggttg
    47161 ggtgaaagat ggagatacct ggtactatct tgaagcatca ggtgctatga aagcaagcca
    47221 atggttcaaa gtatcagata aatggtacta tgtcaatggc tcaggtgccc ttgcagtcaa
    47281 cacaactgta gatggctatg gagtcaatgc caatggtgaa tgggtaaact aaacctaata
    47341 taactagtta atactgactt cctgtaagaa ctctttaaag tattccctac aaataccata
    47401 tcctttcagt agataatata cccttgtagg aagtttagat taaaaaataa ctctgtaatc
    47461 tctagccgga tttatagcgc tagagactac ggagtttttt tgatgaggaa agaatggcgg
    47521 cattcaagag gctctttaag agagttacgg gttttaaact attaagcctt ctccaattgc
    47581 aagagggctt caatctctgc cagggtgcta gcttgcgaaa tggctccacg gagtttggca
    47641 gcgccagatg ttccacggag gtagtgagga gcgaggccgc ggaattcacg aactgcgacg
    47701 ttttctcctt tgaggttaat caatcgtttc aagtgttcgt aggcgatctt catcttgtct
    47761 tcaaaggtca aatcaggtag gatttctcct gtttcaaagt aatggttgat ttggttgaag
    47821 aggtaaggat ttcccatggc agctcggcca atcatgactg cgtcagcacc aacttcttcg
    47881 atgcgttgct tggcttcttg gacagtacgg atatcaccgt tggcgatgaa tggaatcttg
    47941 gttagagctt gggcaacctt gtaaagggtc tcaaggtctg cgtggccagt atacatttgt
    48001 tcacgggtac ggccatgcat ggcgagggca gaaacacctg cagcctcagc agcgagggca
    48061 ttttctactg ccagagatgg gtccgcccag ccggtacgca ttttgacagt aagtgggata
    48121 tcaaggacag actggacctt gttgatgata gagtagatct tgtcaggatc cttgagccac
    48181 atagctccag cttcgttctt cacgattttg ttgacagggc agcccatgtt gatatcgacg
    48241 atatcggtct tggtgttttc ttggatgaat tctgctgcgc gtgctaggct gtcttcatcg
    48301 ctaccaaaaa gttggataga gacagggttt tcgccctcat cgatatgaag catgtgcagg
    48361 gttttttcgt tgttgtattg gattcccttg tcagagacca tttccattac aacgagtcca
    48421 gctccgagct cttttgcgat ggtacgaaag gctgagttgg tcacgccagc cataggcgct
    48481 aaaacggtac gattgggaat ctcaatattg ccaatcataa aaggtgtatt aagatttgtc
    48541 acgaatgagt tcctccaggt ccttttcatc aaagttgtaa gtagtttggc agaattgaca
    48601 agtgatttct gccccgtggt cttcctcttt catttcctgt aagtctgagc ttggaaggct
    48661 ggcaagagcg ttcataaagc gttcatggct acagtcacat tggaaacgga tttcttcttc
    48721 agaaagacgc ttgtaggctt cgtccccgta gatagccttg aggagggctt cgatatggtc
    48781 gtcgctttcg agaagagtag agatagctgg catttcttgg atgcgttttt caaagcgagc
    48841 aatctcttct ttcttggctc ctggcaagac ttgaactagg aaaccacctg caaccttgac
    48901 cttgtcttcc tcgtccaaaa ggacattgag gccgaccgct gaaggcgttt gttggctttc
    48961 agtaaggtaa aaggcaaggt cttcaccgat ttctccagag atgaggggag ttatagagtt
    49021 gtaaggattt ccagcaccgt agtctgtgat aacgaggaat tgaccatttc caacaaaagg
    49081 tccgactagg acttcaccag tcgcagtctt tttgatgtca acaccaggat tttgaacata
    49141 gcctttgacg ttccccttgg tatcagcgac ggtgataata gcacctagag agctagagcc
    49201 caacacctta actgtaagtt tggtatttcc tttttcattg gctgcgagaa tctggctggc
    49261 gataagagtt cgaccaagcg ctacagttga gctagcttgg gtttgatgtt tttcttgagc
    49321 agtgcggacg gtttccgtgc tatcaaggac aaaagcacga aaggctccgc tttctgatat
    49381 agttttaata attttatcca tagctactat tttagcataa aaatgcccaa agggggagcc
    49441 gtgtgtttac tgattttcag gataatggac caggaaatca gcatgaaaat aaaaagagaa
    49501 acagattatt tcagcatttg taagatttat gctatgctta aggtagaaaa tgaaaggggt
    49561 aacaaatgta tttaggagat ttgatggaga aagccgagtg tggtcaattt tcaatccttt
    49621 cctttctatt acaagagtct cagacgaccg tcaaggctgt aatggaagaa acaggatttt
    49681 caaaagcaac cctaaccaaa tatgtcaccc tgctcaatga caaggctttg gatagtggct
    49741 tagagctggc tattcactca gaagatgaaa atctgcgtct gtctatcggt gcagctacca
    49801 aggggagaga tattcggagc ttgtttttgg agagtgctgt taaataccag attttggttt
    49861 atcttctcta ccaccaacag tttttagccc atcagctggc tcaagaattg gtgattagcg
    49921 aggctacgct tggtcgtcac ttggctggtt taaatcagat tttgtcagaa tttgatttat
    49981 ccatccaaaa tggacgttgg cgaggtccag agcatcagat tcgctatttc tatttctgtc
    50041 ttttccgaaa ggtctggtcg agtcaggaat gggaaggtca catgcagaaa ccagagagaa
    50101 aacaggagat tgccaattta gaggaaatct gcggtgcaag tttgtctgtg gggcagaaat
    50161 tggacttggt tctctgggct cacatcagtc aacaacgtct tcgggtcaat gcttgtcagt
    50221 ttcaagtcat agaagagaaa atgcgagggt attttgacaa tattttctac cttcgtttgc
    50281 tgagaaaggt tccgtccttt tttgctgggc aacatattcc actaggagtt gaggatggtg
    50341 agatgatgat attcttctct tttctcctat ctcatcgcat tcttcctctt catactatgg
    50401 agtatattct tggttttgga gggcagttgg cagatttact gacgcaattg attcaagaaa
    50461 tgaagaagga ggaactattg ggggattata cagaggacca tgtcacctat gaactcagtc
    50521 agctttgtgc tcaagtctat ctctataagg gctatatttt acaggatcgc tacaagtacc
    50581 agttagagaa tcgtcatcca tatttactga tggaacatga ttttaaagag acagcagagg
    50641 agatttttca tgctctacct gcttttcaac aggggacaga tttagataag aagattctct
    50701 gggaatggct ccagttaatc gaatatatgg ctgaaaacgg tggccagcat atgcggattg
    50761 gtctggattt gacatctggt tttcttgtct tttcaaggat ggcagccatt ttgaaacggt
    50821 atttggaata caatcgtttt attaccattg aagcttatga ccctagtcgg cattatgatt
    50881 tgctggttac caataacccg attcataaga aggaacagac accagtctat tatttaaaaa
    50941 acgacttgga tatggaagat ttggcaggga ttcgtcagtt attattcact taaaaggctt
    51001 ggttaatcca ggtctttttt gtgaaattca cacaatctcc tcacattttt ttaaaaatta
    51061 aaaaaagttg ataaacaaga aagcgcttta ttttgtatac tagtaagtgt aaagaggaaa
    51121 cacctcaaga tctttatcag gaggacagta catgtcacaa gaaaaataca tcatggccat
    51181 tgaccaggga actacaagtt ctcgtgccat cattttcaac aaaaaagggg aaaaggttag
    51241 ctcgagtcaa aaagagttta cccagatttt ccctcaggca ggttgggttg agcacaatgc
    51301 caatgaaatt tggaactctg ttcagtcagt tattgcgggt gctttcatcg aaagtggtgt
    51361 caagccaaat caaatcgagg caatcgggat taccaaccaa cgtgaaacaa cggttgtctg
    51421 ggataagaaa acaggacttc ctatctacaa tgctatcgtt tggcagtcac gccagacagc
    51481 acctttggct gagcaactaa aaagccaagg ttatgtggaa aaattccatg aaaagactgg
    51541 tttgattatt gatgcttact tctctgctac caaggttcgt tggattttgg atcatgtaga
    51601 aggtgctcaa gagcgagcag aaaaagggga attgctcttt ggtactatcg atacttggtt
    51661 ggtttggaaa ttgactgacg gtgcggctca cgtgactgac tactcaaatg cagctcgtac
    51721 catgctttat aacattaaag aactcaaatg ggatgatgag attttggaaa tccttaacat
    51781 tccgaaggct atacttccag aagttcgttc taactccgaa atctacggca agacagctcc
    51841 attccatttc tacggtggag aggtgccaat ctcaggtatg gctggggacc aacaagcagc
    51901 cctctttgga cagttggctt ttgagccagg tatggttaag aatacttatg gaacaggctc
    51961 tttcatcatc atgaatactg gggaagagat gcagttgtct gaaaacaacc tcttgacaac
    52021 cattggttac ggaatcaacg gtaaggttta ttatgccttg gaaggttcta tcttcatcgc
    52081 aggaagtgct attcagtggc ttcgtgacgg tcttcgcatg gttgaaaatt caccagaatc
    52141 tgaaaaatac gctcgtgatt ctcacaacaa cgatgaagtt tatgtcgttc cagcctttac
    52201 aggtctaggc gctccatact ggaaccaaaa tgctcgtggt tccgtctttg gtttgactcg
    52261 tggaacaagc aaagaagact ttatcaaggc gactttgcaa tctattgctt atcaagtgcg
    52321 tgacatcatc gacaccatgc aagtggatac tcagaccgcc attcaagtac tgaaggtgga
    52381 tggtggtgca gccatgaaca acttcctcat gcagttccag gcggatattt taggcattga
    52441 tattgcacgt gctaaaaact tggaaacaac agctctagga gcggccttcc tagcaggttt
    52501 atcagtaggg tattggaaag acttggacga gttgaaactc ttgaacgaga caggagaact
    52561 ctttgagcca tctatgaacg aatctcgcaa ggaacaactc tacaagggct ggaagaaggc
    52621 tgtgaaagca actcaagtct ttgcggaagt agacgactaa tactggcaga ataaagcgat
    52681 ttatttagaa agtgtgtaaa tatggaattt tcaaagaaaa cacgtgaatt gtcaattaaa
    52741 aaaatgcagg aacgcaccct ggacctcttg attatcggtg gaggaatcac aggagctggt
    52801 gtagccttgc aggcggcagc tagcggtctt gagactggtt tgattgaaat gcaagacttt
    52861 gcagaaggaa catctagtcg ttcaacaaaa ttggttcacg gaggacttcg ttacctcaaa
    52921 caatttgacg tagaagtggt ctcagatacg gtttctgaac gtgcagtggt tcaacaaatc
    52981 gctccacaca ttccaaaacc agacccaatg ctcttaccag tttacgatga agatggagca
    53041 acctttagcc tcttccgtct caaagtagcc atggacttgt acgacctttt ggcaggtgtt
    53101 agcaacacac caactgcgaa caaggttttg agcaagaaag aagtcttgga acgccagcca
    53161 aacttgaaga aggaaggctt ggtaggaggt ggagtgtatc ttgacttccg taacaacgat
    53221 gcgcgtctcg tgattgaaaa catcaaacgt gccaaccaag acggtgccct cattgccaac
    53281 cacgtgaagg cagaaggctt cctctttgac gaaagtggca agattacagg tgttgtagct
    53341 cgtgatctct tgacagacca agtatttgaa atcaaggccc gtctggttat taatacaaca
    53401 ggtccttgga gtgataaagt acgtaatttg tctaataagg gaacgcaatt ctcacaaatg
    53461 cgcccaacta agggagttca cttggtagtg gattcaagca aaatcaaggt ttcacagcca
    53521 gtttacttcg acacaggttt gggtgacggt cgtatggtct ttgttctccc acgtgaaaac
    53581 aagacttact ttggtacaac tgatacagac tacacaggtg atttggagca tccaaaagta
    53641 actcaagaag atgtagatta tctacttggc attgtcaaca accgctttcc agaatccaac
    53701 atcaccattg atgatatcga aagcagctgg gcaggtcttc gtccattgat tgcagggaac
    53761 agtgcctctg actataatgg tggaaataac ggtaccatca gtgatgaaag ctttgacaac
    53821 ttgattgcga ctgttgaatc ttatctctcc aaagaaaaaa cacgtgaaga tgttgagtct
    53881 gctgtcagca agcttgaaag tagcacatct gagaaatatt tggatccatc tgcagtttct
    53941 cgtgggtcta gcttggaccg tgatgacaat ggtcttttga ctcttgctgg cggtaaaatc
    54001 acagactacc gtaagatggc tgaaggagct atggagcgcg tggttgacat cctcaaagca
    54061 gaatttgacc gtagctttaa attgatcaat tctaaaactt accctgtttc aggtggagaa
    54121 ttgaacccag caaatgtgga ttcagaaatc gaagcctttg cgcaacttgg agtatcacgt
    54181 ggtttggata gcaaggaagc tcactatctg gcaaatcttt acggttcaaa tgcaccgaaa
    54241 gtctttgcac ttgctcacag cttggaacaa gcgccaggac tcagcttggc agataccttg
    54301 tcccttcact atgcaatgcg caacgagttg gctcttagcc cagttgactt ccttcttcgt
    54361 cgtaccaacc atatgctctt tatgcgtgat agcttggata gcatcgttga gccagttttg
    54421 gatgaaatgg gacgattcta tgactggaca gaagaagaaa aagcaactta ccgtgctgat
    54481 gtcgaagcag ctctcgctaa caacgattta gcagaattaa aaaattaaga aaaaataaaa
    54541 gaggtggagg gcagcattcc ttgtcgcccg tcccttcttt ttaatggaga cagaaagatg
    54601 atgaatgaat tatttggaga atttctaggg actttaatcc tgattcttct aggaaatggt
    54661 gttgttgcag gtgtggttct tcctaaaacc aagagcaata gctcaggttg gattgtgatt
    54721 actatgggtt gggggattgc agttgcggtt gcagtctttg tatctggcaa gctcagtcca
    54781 gctcatttaa atccagctgt gacagttggt gtagctttaa aaggtgactt gccttgggct
    54841 tccgttttgc cttatatctt agcccagttc gcaggggcca tgctgggtca gattttggtt
    54901 tggttgcaat tcaaacctca ctatgaggca gaagaaaatg caggcaatat cctggcaacc
    54961 ttcagtactg gaccagccat caaggatact gtatcaaact tgattagcga aatccttgga
    55021 acctttgttt tggtgttgac aatctttgct ttgggtcttt acgattttca ggcaggtatc
    55081 ggaacctttg cagtgggaac tttgattgtc ggtatcggtc tatcactagg tgggacaaca
    55141 ggttatgcct tgaacccagc tcgtgacctt ggacctcgta tcatgcacag catcttgcca
    55201 attccaaaca agggagacgg agactggtct tacgcttgga ttcctgttgt aggccctgtt
    55261 atcggagcag ccttggcagt gcttgtattc tcacttttct agtttatact cttcgaaaat
    55321 caaattcaaa ccacgtcagc gtcgccttac cgtactcaag tacagcttgc ggctagcttc
    55381 ctagtttgct ctttgatttt cattgagtat tagaaaacaa ttatgttgat agagcttggg
    55441 caagagccca atttcagcaa aaaatgaagt aaatcttctc ataataaaac gcatcatatc
    55501 aagcacgaaa attccacgag gtcaactaca gtcagaaagc tgaacaacaa gccaaaacgc
    55561 ccaaaaaagg cggcaaaaag caagcacctg caagcaacgt gccgaaatgg tcaaatcctg
    55621 attatgtcaa cgaattagac ccaaaaatcg ttgatatgct agtagaattt cacaagtcac
    55681 aaggcacttt ggaaactccc gaggcgcaag cagaaatcgc ccaaaaacgt gaagaaatcg
    55741 agcaaaggag agctgagctt gagggtaaaa aacaagagct tttgaaccgc ttgaacaaat
    55801 agagtttcgc aagtattatg cttacaaatt acttgagcaa ttaactaaaa tataaactct
    55861 gcctagatat aaaggcaggg tttatatttt agaaattcac gtaggttgtt acggttttta
    55921 catacccagt atagtttgag tttctatagt attcagtgat aaacttccat tttctttgag
    55981 caacatggat ataagtactt gttatgtagt atggatatgg gctttgtgaa tccaagtaag
    56041 actgataagc ttgtatacca aaatatgctc caccaattat tgcaccccat ggacccccca
    56101 ataaagcacc tatcctacca atcatataac tgattccagc accagtcatg aagttagcga
    56161 atgtgttagc ttgtttattc ccatgtattg tgttgacgta attccaaaca ttaggatcgt
    56221 atgatctaaa agatatattt aggtcgattt cattcttttg ataagccata taaaatgccc
    56281 cattgatata gacgccgtca gcacgtcgtt caatagtgtc tacacttcca tctggattga
    56341 caacctcaag aacttcatcg cttaaaatat ttacttgcgt atctccgaac cgcactgatg
    56401 agccattctc aaactgagcc tcaccagata caactttaga gtttgccgat aagctatcat
    56461 cagcaaaaac aacaagcgac ggggaaatgc tagacataca gaaaacagac ataactagca
    56521 aacacatgca tttaaacatc ttagacataa cggaaactct tttgtatttt tgattttttt
    56581 caacttttat tatacaataa aaccaaataa aaagaaagcg gtaacaatat gcttaatgcg
    56641 aaaatttttt atatattttt atgtttgatc gttatcgaaa ctacaggctt gttgttgttg
    56701 aaaagaggtc tcgaaatggg ttatttagac acagaagcta ttatcctcgc agttttttca
    56761 tttgcttttt acaacctatg ttcattcgct tgggtctgct ctacaataaa aaacaataaa
    56821 aaataaatag acgtattttc aaaaaaaaaa aaaaaaatgc atatttatat tagcaaaatg
    56881 acgatttaaa tcgtcgtttt tttgtagtac gacgggcatg tcgtatatct gaggtgtaag
    56941 tcctcggtgg gcacctg
//
LOCUS       DAVKMJ010000006        56923 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000006 DAVKMJ010000000
VERSION     DAVKMJ010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56923
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.006"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(99..632)
                     /gene="queF"
                     /locus_tag="VW348_000361"
     CDS             complement(99..632)
                     /gene="queF"
                     /locus_tag="VW348_000361"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HEU9745334.1"
                     /translation="MKRQSALVVFSGGQDSKTCLFWTMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(939..1253)
                     /gene="trxA"
                     /locus_tag="VW348_000362"
     CDS             complement(939..1253)
                     /gene="trxA"
                     /locus_tag="VW348_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEU9745335.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(1270..1491)
                     /locus_tag="VW348_000363"
     CDS             complement(1270..1491)
                     /locus_tag="VW348_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU9745336.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(1590..1970)
                     /locus_tag="VW348_000364"
     CDS             complement(1590..1970)
                     /locus_tag="VW348_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU9745337.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(2115..3068)
                     /locus_tag="VW348_000365"
     CDS             complement(2115..3068)
                     /locus_tag="VW348_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU9745338.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(3136..4344)
                     /gene="sstT"
                     /locus_tag="VW348_000366"
                     /pseudo
     CDS             complement(3136..4344)
                     /gene="sstT"
                     /locus_tag="VW348_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            4483..5043
                     /locus_tag="VW348_000367"
     CDS             4483..5043
                     /locus_tag="VW348_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEU9745339.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            5100..6008
                     /locus_tag="VW348_000368"
     CDS             5100..6008
                     /locus_tag="VW348_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEU9745340.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            5960..6550
                     /locus_tag="VW348_000369"
     CDS             5960..6550
                     /locus_tag="VW348_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEU9745341.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            6553..7659
                     /gene="yqeH"
                     /locus_tag="VW348_000370"
     CDS             6553..7659
                     /gene="yqeH"
                     /locus_tag="VW348_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEU9745342.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            7873..8184
                     /gene="yhbY"
                     /locus_tag="VW348_000371"
     CDS             7873..8184
                     /gene="yhbY"
                     /locus_tag="VW348_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEU9745343.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            8236..8865
                     /locus_tag="VW348_000372"
     CDS             8236..8865
                     /locus_tag="VW348_000372"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEU9745344.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVEYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            8865..9458
                     /gene="yqeK"
                     /locus_tag="VW348_000373"
     CDS             8865..9458
                     /gene="yqeK"
                     /locus_tag="VW348_000373"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEU9745345.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVGKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            9459..9959
                     /locus_tag="VW348_000374"
     CDS             9459..9959
                     /locus_tag="VW348_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU9745346.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEEHFADVL
                     DYKHIF"
     gene            9972..10325
                     /gene="rsfS"
                     /locus_tag="VW348_000375"
     CDS             9972..10325
                     /gene="rsfS"
                     /locus_tag="VW348_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEU9745347.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            10428..11174
                     /locus_tag="VW348_000376"
     CDS             10428..11174
                     /locus_tag="VW348_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9745348.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKEKKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEAPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            11184..12281
                     /locus_tag="VW348_000377"
     CDS             11184..12281
                     /locus_tag="VW348_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEU9745349.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVNILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTARSVEELVELVTTKRY
                     TKARVRRLLTYILMQARENVLPEVIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKADQIYQLGNPSIADQNFGRVPIRIETN"
     gene            12519..12773
                     /locus_tag="VW348_000378"
     CDS             12519..12773
                     /locus_tag="VW348_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEU9745350.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            12777..13031
                     /locus_tag="VW348_000379"
     CDS             12777..13031
                     /locus_tag="VW348_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HEU9745351.1"
                     /translation="MLLKFTEDAWADYCYWQNQDKKTLKRINKLIKDIQRDPFTGIGK
                     PEPLKYDYQGAWSRRIDAENRLIYMMDGDSVAFLSFKDHY"
     gene            13222..14835
                     /locus_tag="VW348_000380"
     CDS             13222..14835
                     /locus_tag="VW348_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEU9745352.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            14965..15591
                     /gene="gmk"
                     /locus_tag="VW348_000381"
     CDS             14965..15591
                     /gene="gmk"
                     /locus_tag="VW348_000381"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEU9745353.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            15616..15930
                     /locus_tag="VW348_000382"
     CDS             15616..15930
                     /locus_tag="VW348_000382"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEU9745354.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            15996..18392
                     /locus_tag="VW348_000383"
     CDS             15996..18392
                     /locus_tag="VW348_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEU9745355.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQVRILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTRNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            18405..19340
                     /locus_tag="VW348_000384"
     CDS             18405..19340
                     /locus_tag="VW348_000384"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEU9745356.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPNRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSICKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            19333..20646
                     /gene="rsmB"
                     /locus_tag="VW348_000385"
     CDS             19333..20646
                     /gene="rsmB"
                     /locus_tag="VW348_000385"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEU9745357.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVALKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFANGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            20661..21401
                     /locus_tag="VW348_000386"
     CDS             20661..21401
                     /locus_tag="VW348_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEU9745358.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            21398..23377
                     /gene="pknB"
                     /locus_tag="VW348_000387"
     CDS             21398..23377
                     /gene="pknB"
                     /locus_tag="VW348_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEU9745359.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            23492..24250
                     /locus_tag="VW348_000388"
     CDS             23492..24250
                     /locus_tag="VW348_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU9745360.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            24252..24701
                     /locus_tag="VW348_000389"
     CDS             24252..24701
                     /locus_tag="VW348_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEU9745361.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            24763..25389
                     /locus_tag="VW348_000390"
                     /pseudo
     CDS             24763..25389
                     /locus_tag="VW348_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            25457..25705
                     /locus_tag="VW348_000391"
     CDS             25457..25705
                     /locus_tag="VW348_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745362.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            25836..27008
                     /locus_tag="VW348_000392"
     CDS             25836..27008
                     /locus_tag="VW348_000392"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEU9745363.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTVLSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            27008..28282
                     /locus_tag="VW348_000393"
     CDS             27008..28282
                     /locus_tag="VW348_000393"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEU9745364.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQDDPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVEQLIADKTFNLETAQRYLENLRS"
     gene            complement(28318..29283)
                     /locus_tag="VW348_000394"
     CDS             complement(28318..29283)
                     /locus_tag="VW348_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9745365.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVTTTGYFLPVTLLPGKSI"
     gene            complement(29264..30718)
                     /locus_tag="VW348_000395"
     CDS             complement(29264..30718)
                     /locus_tag="VW348_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU9745366.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            30771..30968
                     /locus_tag="VW348_000396"
     CDS             30771..30968
                     /locus_tag="VW348_000396"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745367.1"
                     /translation="MQAFYVKKEEKLSKDYHKINTGNQSNFYENVKDNEIKDFLTKVS
                     NLFFKEFLMKQSKTINLKLAH"
     gene            31094..32977
                     /locus_tag="VW348_000397"
     CDS             31094..32977
                     /locus_tag="VW348_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU9745368.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFIIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFETKV
                     AQGDKVKVGDVLGTFDSNKIAAAGLDDTTMVIVTNTGDYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            33126..34013
                     /locus_tag="VW348_000398"
     CDS             33126..34013
                     /locus_tag="VW348_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU9745369.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(34056..34673)
                     /locus_tag="VW348_000399"
     CDS             complement(34056..34673)
                     /locus_tag="VW348_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEU9745370.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(35088..35276)
                     /locus_tag="VW348_000400"
                     /pseudo
     CDS             complement(35088..35276)
                     /locus_tag="VW348_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(35786..35866)
                     /locus_tag="VW348_000401"
                     /pseudo
     CDS             complement(35786..35866)
                     /locus_tag="VW348_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            35982..36875
                     /locus_tag="VW348_000402"
     CDS             35982..36875
                     /locus_tag="VW348_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9745371.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            36872..38071
                     /locus_tag="VW348_000403"
     CDS             36872..38071
                     /locus_tag="VW348_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9745372.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLEQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(38424..39191)
                     /locus_tag="VW348_000404"
     CDS             complement(38424..39191)
                     /locus_tag="VW348_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745373.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(39208..39903)
                     /locus_tag="VW348_000405"
     CDS             complement(39208..39903)
                     /locus_tag="VW348_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9745374.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(39908..40273)
                     /locus_tag="VW348_000406"
     CDS             complement(39908..40273)
                     /locus_tag="VW348_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9745375.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMIH
                     FGYEKEELPGVVSDYIKGV"
     gene            40413..40886
                     /gene="nrdR"
                     /locus_tag="VW348_000407"
     CDS             40413..40886
                     /gene="nrdR"
                     /locus_tag="VW348_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEU9745376.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            40887..42056
                     /locus_tag="VW348_000408"
     CDS             40887..42056
                     /locus_tag="VW348_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEU9745377.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFNPKEATIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKTKTQKQNQTAPAKTNIPKWSNPDYKNETSEETRLELERKKQELLARLEKGGD"
     gene            42057..42953
                     /gene="dnaI"
                     /locus_tag="VW348_000409"
     CDS             42057..42953
                     /gene="dnaI"
                     /locus_tag="VW348_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEU9745378.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            42950..43663
                     /locus_tag="VW348_000410"
     CDS             42950..43663
                     /locus_tag="VW348_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEU9745379.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAKMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            43677..44987
                     /gene="der"
                     /locus_tag="VW348_000411"
     CDS             43677..44987
                     /gene="der"
                     /locus_tag="VW348_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEU9745380.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            45078..45413
                     /locus_tag="VW348_000412"
     CDS             45078..45413
                     /locus_tag="VW348_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745381.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            45553..45888
                     /locus_tag="VW348_000413"
     CDS             45553..45888
                     /locus_tag="VW348_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745382.1"
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            46073..46864
                     /locus_tag="VW348_000414"
     CDS             46073..46864
                     /locus_tag="VW348_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745383.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILHVVPYMVLKKYEDNV"
     gene            46857..47498
                     /locus_tag="VW348_000415"
     CDS             46857..47498
                     /locus_tag="VW348_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745384.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLIVSRLEEKFKKG"
     gene            47502..48152
                     /locus_tag="VW348_000416"
     CDS             47502..48152
                     /locus_tag="VW348_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9745385.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            48163..48450
                     /locus_tag="VW348_000417"
     CDS             48163..48450
                     /locus_tag="VW348_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745386.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     MQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            48596..51109
                     /gene="secA"
                     /locus_tag="VW348_000418"
     CDS             48596..51109
                     /gene="secA"
                     /locus_tag="VW348_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEU9745387.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMATLTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQAMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            51190..52221
                     /locus_tag="VW348_000419"
     CDS             51190..52221
                     /locus_tag="VW348_000419"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU9745388.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            52223..53254
                     /locus_tag="VW348_000420"
     CDS             52223..53254
                     /locus_tag="VW348_000420"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEU9745389.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            53293..53661
                     /locus_tag="VW348_000421"
     CDS             53293..53661
                     /locus_tag="VW348_000421"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEU9745390.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            53651..54754
                     /locus_tag="VW348_000422"
     CDS             53651..54754
                     /locus_tag="VW348_000422"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEU9745391.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLALPYDLIPALTLESALVHIKTVPAGACMGYGATYQTDSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            54773..56788
                     /gene="recG"
                     /locus_tag="VW348_000423"
     CDS             54773..56788
                     /gene="recG"
                     /locus_tag="VW348_000423"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEU9745392.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHYMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIETWQEDPEWRMIALHLEKKEHLD"
BASE COUNT        16827 a        10960 c        12989 g        16147 t
ORIGIN      
        1 agctgacttc gtcagtttta tctacaacct caaacactgc tttgagtaac ctgcggctaa
       61 cttcctagtt tgctctttga ttttcattga gtatgacttt agcggttgtc aattttctct
      121 ggataaaggt cgtgttggaa gaggcgttgt tctgccaagc cctcatactt agttccttgc
      181 ttaccgtagt tatagtaggg gtcgattgaa atgccaccgc gcggagtgaa ttttccccag
      241 acttctaaat agcgagggtc tagcaagttg accaagtctt tcccgatggt gttgatacag
      301 ttttcgtgga aatctccgtg gtttcggtag ctaaatagat atagtttgag ggattttgac
      361 tcgacacaga gcttgtcagg aatgtaggaa atatgaatcg tcgcaaagtc tggctgagca
      421 gtgatttgtc ccagcagaga catatcgagg atatggtgac gaatgccctg ttccttagcg
      481 atttctctag taatttgaat ttcgaggtga tgacgttggc cgtaggcaaa ggtgacagct
      541 tcgactgttt catagtgttg catggtccag aaaaggcagg tttttgaatc ttgaccacca
      601 ctaaagacga ccaaggctga ttgacgtttc atagtactcc ttccaaaatg ggaaatgttc
      661 agagcacgta aaaagctccc attagggagc taaaaaatac caaatcgagg ttttttttag
      721 cgatggcata tcccaaatat cgtaatattc tatttatata gtaaaatgaa ataagaacag
      781 gacaaatcga tcaggacagt caaatcgatt tctaacaatg ttttagaagt agagatgtac
      841 tattctagtt tcaatctact atagtctagc atatcttttg aaaaatggca aagggcaaga
      901 aaaaagagac caaagaaagt acttggtctc tcgtttgatt agctcaattc agcaatgatg
      961 gccttgattt gttctgctgt gtgaacacct gcaacttgtt tgacaacttg gccgtctttt
     1021 ttgaagagaa gagttggaat agacatgatt ccaaaagcac gagctgtgtt tggattttca
     1081 tcaacgtcca ttttaacgat tttcaagaca tcttctgaaa gttcttcaga caatttgtcc
     1141 aagattggac cttgcatacg acatggacca caccaagttg cccagaagtc tactaagacc
     1201 aaaccgtctt ttgtttcttg ttcgaatgtt gcatctgtaa ttgcttttgc cattgtattt
     1261 ctcctttttt tagttatatt ggcttaaatc ttgtttcatg agatagaaga agatatctcc
     1321 ataagtccca tggtagtcca aattatgacc cttgtaagtt aatttttgga cagggtagta
     1381 gtctgcgacg ccgataaggc aagcttgttg cgaacgttca aagtcttcat aagactcgaa
     1441 agtcacagtt ctttcgttct tgctggcatc tatataggta atttcaatca tgtttaaaac
     1501 tcctttgttt aatgctaact ttattttact ccttataaaa gagaatgtca agaaaaatga
     1561 ttgcgcacgc aacttttttt aaaatcatct taaatcaaga aatccaaacc tgcttccaag
     1621 ctttcttcga cagtcttttg tagcgaggcc agtgtctttt gcccatcatt tgtcaggcag
     1681 ataaaactag agcgtctatc ttgatggcaa cacatgcgac tgagtagacc gcaattttta
     1741 gcttccaagc gagccaccat cctagaaact gcgctcgggc tcagatgaag cttatctggc
     1801 aggtcaatct ggcgtagaga tttttcttca gccaagtcca gatagtagag caggtagaac
     1861 tctttcaagg tcagactttg ctcgctctgt tgggcaatgg tctcttccaa gagactttca
     1921 atttctttct gacgccgatt gaagtcaaac catttttcca aataggtcat agtgtctcct
     1981 ttctttttag agtcataatt atagaagaaa gtccattaac gggcagtctt tgcgtcataa
     2041 gatgattgcg catgcaataa ttatactact tttcaagaat gctggcaagc tctgtttttt
     2101 agtggttttc ttttttactg tctatatttt tggtaaaaat caacttttac ttggatgaag
     2161 gttttggctt cacgtaggag ttgaagaaga gtggcgcggg tttcaaactc ttctcttgtc
     2221 ttgggcagac tgcggttccg gaagacttcc agataacgtt caatttcatc tagcaaatca
     2281 gaagcaggat tggtctggct cagttgacct gcaatttttg aaaagagttg cgctaagatc
     2341 aggctttcac tggcggcaag gtgacaagtg ttaatctgtt gggccatgtt tctcaggata
     2401 cgactttgtc gttgtctcat ctcaaagtag tggatatggt agtcggtctg gtgaaagagg
     2461 tggtcagagt gatccaaata gaccagtctg agggcttctt tcaaaagcgt gtctaattct
     2521 gctaccagct gtgctcggtt gcgtccgtct cctctggata aatagtattt gaagcgctgg
     2581 aggatatctt ttaacttttc ttccaccagc gtgtggtagt gctggatttc ctcttctcgt
     2641 gaaggcatat agagattaac aagcaaggca aatcctgtac caatagcaaa gagaaggaat
     2701 tcgttgacta ggaggtctgg agaggttgac tcttgaacca agagatggct aaccaaaacc
     2761 gtgcttggtg tgatgccaat ttcccagccc atcttgtagg ctaaaggaac gtagaaggcc
     2821 agatagaggc cgagactcca gatatgaaat ccgctcaagt gaaaagctag aacgccgata
     2881 gccagagcta gaagcataga aaaaagacga ttgcgagcca gttttaaagt acttctacgc
     2941 gtatcagata ggctcaagag agcgataatt ccagccgaaa ctgctgacga aagattgaga
     3001 aaataagcaa gcaggcaggc aagacaggta gctaagatga gcttggtcgt acgttggcta
     3061 atagacataa gaatttccta ataagttaga ataaaagcgt aaaagacaag acatgagcag
     3121 gcttgccttg atgagttatt ttttacgggt tgctgcgtat tcggcaacgg cggtaaagag
     3181 gacatctgta gaagagttaa gggctgtttc acatgagtct tggatgacac caatcacaaa
     3241 accaacccca acaatttgta tggcaatatc gttagaaata ccgaaaaggc tacaagcaac
     3301 tgggataaga aggagggaac ctccggcaat acctgaagca tcacaggctg agatagctgc
     3361 taccacactg aggacaaagg ctgtggcaaa gtcaacagga attccaagag tgttaactgt
     3421 aacaagggtc aaaacgttaa tggtaatcgc tactccagcc atattgatag tagaaccgag
     3481 tgggatagaa acagaatagg tatctgggtt gagtccaagg tcatggcaga gtttcatgtt
     3541 gacaggaatg ttagtcgcag aactacgagt gaaaaaggct gtcacaccgc tgacacggag
     3601 gcagttccaa actagagggt aaggattgcg tctcataaag aagaaggcaa tcaaagggtt
     3661 gaccacaggg gcaacaaaaa gcatagtcgt tactaataga accaataaaa taccgtagtt
     3721 ggcaaggctt ccgactccct tgtcagaaat ggttttaaaa acaagaccaa ggattccaaa
     3781 tggagccaga ttgatgatcc attcgacaat tttagaagtc acgtcagcga tagtttttag
     3841 caattcttta ctatttttac tggcttctct catagcgatt ccaaaaatga ctgcccaaga
     3901 taagattcta atatagttag cagtaagcag ggcgttgact gggttgtcaa ccagtttgag
     3961 caagaggttg ctgaggacct gcccaatccc atctggtggt gcaatttcag tattggcact
     4021 atttagggta atttcaatag ggacgatgaa acttgctagt acagctacaa gagcagcggc
     4081 gaaagtccct atcataggat atacaagaaa acaacagttt tcatattgct atcttgtccc
     4141 ttttgatgtt ggaaagggca ttggcaacga gggcaaagac taggatagga gcaacagctt
     4201 ttagacctcc aacgaataaa tccccgagta gcccaatccc tgagagatta ggaagggtca
     4261 gtcctaggat tccccacaaa gcataccaat caagatacgc ttgacaaggc ttgccttatt
     4321 ccaagcatga atgattcttt tcataataat ctcctttttg tgtagtgatt atgattatag
     4381 tataaatgat agacaaaatc aagaattttc tgtctatttt ttgaatattt atggagaatg
     4441 agactgatga aaatatggta taatgaaata aaggagtttt atatgcaaaa atttattcag
     4501 gcttatattg aaaagctaga tgtgacaacc attatcgaga atattctaac caaggtcatt
     4561 tctcttttac tgcttttgat tgtattttat attgctaaaa aaatgcttca taccatggtg
     4621 cagagaattg tcaaaccttc tctaaaaatg tctcgtcatg atgtcggacg ccaaaaaacc
     4681 atctcacgtt tactagaaaa tgtgtttaat tatacgctat atttcttttt actctactgc
     4741 attttgtcga ttttaggttt gccagtttct agtttgctgg ctggagctgg tattgctggg
     4801 gtagcgattg gtatgggagc ccaaggcttt ctgtctgatg tcatcaatgg ctttttcatc
     4861 ctctttgaac gtcaactgga tgtgggagat gaggtcgttc tgacaaatgg accgattact
     4921 gtatcgggta aggttgtcag tgtgggaatt cgtacgacac agcttcgtag cgaggagcaa
     4981 gcccttcact ttgtccctaa ccgaaatatc acagttgtta gcaatttctc acgcacagac
     5041 tagacctgtt attttaagta atttgtggta caatagaggg agtttaataa ggagaaaaga
     5101 tggttttaga aaagcagttg ggcaatggtt gtacctggat agacctagac ctaggaaagt
     5161 tgaataaact agaagacctt tctgaaattt acggtttgga caaggaaacc attgaatacg
     5221 cactggatag aaacgagcgc gcccacatgg attaccaccg tgaaagtggg acggttacct
     5281 ttatctataa tgtcctagac gtaaaaaagg acaaggccta ctatgagact tttcccatga
     5341 cctttattgt cgagcatcgt cgcctgatta ccattagtaa taccaagaac gcctatgtca
     5401 ttgaacagat gactcgttat ctggagagcc atgacacgct ttcgatttat aagtttctct
     5461 ttgccagtct ggaaattatc agcaatgcct actatcctgt cattgagcag atggacaaga
     5521 gtagggatga ggtcaatgac ctcttgcgcc agcgaactac caagaaaaac ctctttgccc
     5581 tgtctgattt ggagactggt atggtttatc tgacggcagc tgccaaacaa aatcggattt
     5641 tgttagagca tattcaaggt catgccttgt atcgtagttt tgatgagatt gagagagaac
     5701 agtttgatga tgccatgatt gaggctcatc agctggtatc catgacagac ctaatctctc
     5761 agattttaca gcagctttca gcctcttaca acaatattct aaacaataat ctgaatgaca
     5821 atttgacaac cttgactatc atttcagtct tgctagctgt tttggcagtc gtgacaggct
     5881 ttttcggaat gaatgttccc ttacctttaa cagatgagcc ccatgcttgg ctctatatca
     5941 gtttggctag tgcaggtttg tggattgttt tatccttgtt actaaggaaa attgcgaaaa
     6001 aaagttaaga aaaggagcca gaatggcgat tgaaaattat ataccagatt ttgctgtgga
     6061 agcagtctat gatctgacag tcccaagcct gcaggcgcag ggaatcaagg ctgttttggt
     6121 cgatttggat aataccctca ttgcttggaa caaccctgat ggaacgccag agatgaagca
     6181 atggctacat gaccttcggg acgcgggtat tggcattatc gtagtgtcaa ataacaccaa
     6241 aaaacgcgtt caacgagcag ttgagaaatt tgggattgat tacgtttact gggccttgaa
     6301 gcccttcaca tttggtattg accgtgctat gaaggaattc cactatgaca aaaaggaagt
     6361 ggtcatggtt ggcgaccagc tcatgacaga tatacgagca gcccaccgtg cagggattcg
     6421 gtcaatttta gtcaaaccct tggtccaaca tgactcaatc aaaacgcaga ttaaccgaac
     6481 tcgtgagcgt cgtgttatga gaaaaatcac tgaaaagtac ggaccgatta catataaaaa
     6541 aggaatttaa ctatggaaga aattctctgt attggttgtg gagcaaccat tcagacgaca
     6601 gataaagctg gtcttggttt taccccccag tcggcacttg aaaaaggttt ggagactggc
     6661 gaagtctatt gccaacgctg tttccgtctc cgccactaca atgaaatcac agatgtccag
     6721 ttgacgaacg atgatttcct caagctcttg cacgaggtgg gagacagtga tgccttagtg
     6781 gtcaatgtca ttgatatctt tgattttaat ggatctgtca tcccaggttt accacgtttc
     6841 gtctcgggca atgatgtcct cttggtagga aataaaaaag atatccttcc taagtcagtt
     6901 aagtctggta agattagcca gtggctcatg aaacgtgccc atgaagaagg tcttcgtcca
     6961 gtcgatgtgg tcctaacttc agcacaaaat aaacatgcca ttaaggaagt cattgacaag
     7021 attgaacact accgtaaggg ccgcgatgtc tatgtggtcg gtgtgaccaa cgttggaaaa
     7081 tcaactctaa tcaatgctat tatccaagaa atcacgggtg atcagaatgt catcactact
     7141 tcacgcttcc caggtacaac cttggacaaa atagagattc cgcttgacga cggatcttat
     7201 atttacgata cgccgggaat tatccaccgc caccagatgg ctcactactt gacggccaaa
     7261 aacctcaagt atgtcagtcc taaaaaggaa atcaagccta agacctatca gcttaatcct
     7321 gagcaaaccc tatttttagg tggtttggga cgctttgact ttatagcagg agaaaagcaa
     7381 ggatttactg ctttctttga taatgaactc aaactccatc gtagcaagct tgaaggagct
     7441 agtgctttct acgataagca cctgggaact cttctgacac caccaaatag caaggaaaaa
     7501 gaagatttcc caaggctagt ccagcatgtc tttaccatta aagataagac agacctagtc
     7561 atctcaggcc taggctggat tcgtgtaaca ggcatagcaa aagtcgccgt ctgggcacca
     7621 gaaggcgtcg ccgtcgtcac acgaaaagca attatttaaa acaaaatcgc tgagcgaaca
     7681 aagtgagctc atatagcgat agttattgcc gtggtgtgat tgccaatctg tagattggca
     7741 aggggcacaa ttgagaccaa ggctcaattg tgaggtcagg aaatccattt ttcaaagatg
     7801 aaatctttgg aaaattagtt ccgaccgtcc ctcaccacct aaaataacta tccaaaaaca
     7861 aggaagaaaa ttatgtcatt aacatcaaaa caacgtgcct tcctcaacag ccaggcacac
     7921 accctcaaac ctatcatcca aatcgggaaa aatggactca acgaccaaat caaaaccagc
     7981 gtccgtcaag ctcttgatgc gcgtgaatta atcaaggtta ctctcttaca aaacacagat
     8041 gaaaacatcc acgaagtagc tgaaattttg gaagaagaaa tcggtgtgga tacagtccaa
     8101 aaaataggac gcatcttgat tttgtttaaa caatctagca agaaagaaaa tcgcaagatt
     8161 tctaagaaag tcaaagaaat ctaagaccga aactccaaat aactgttttt atagagaaat
     8221 aaaggggact agcctatgac aatcgaacta ttgactccct ttaccaaggt agagttggag
     8281 ccagaaatca aggagaaaaa acgcaaacaa gttgggattt taggggggaa ttttaaccct
     8341 gttcacaatg cccatctcat tgttgcggat caagtacggc aacagttggg actggatcaa
     8401 gttcttctca tgcctgaata ccaacctcct cacgttgata aaaaggaaac catccctgaa
     8461 caccatcgtc tcaagatgct tgagttggca attgagggaa ttgacggcct agtcattgaa
     8521 accattgagt tggagcgcaa gggtatttcc tacacctacg acaccatgaa gattttgaca
     8581 gagaagaatc cagatacgga ttattacttt atcatcggtg ccgacatggt tgagtatctg
     8641 cctaagtggt accgaattga tgaactggtt gacatggttc agtttgtggg ggttcagcgt
     8701 ccacgctaca aggtagggac ttcctatcca gttatctggg tggacgtacc gctcatggat
     8761 atctcgtcca gcatggtgcg ggacttcctt gcccaaggtc ggaaacccaa ctttctccta
     8821 cctcagccag tgctagacta catcgagaag gaggggctct actgatgtcc tatcaagact
     8881 atatcaactg ctcccgtgag gccttgttgg aaaaaatggc agagcttcta cctgagaaac
     8941 gtctaaccca ttgtctaggt gtggagcgtg ccgctatgga attagctcag cgctttggtg
     9001 tagatgttgg gaaagcaagt ctagcaggtc ttcttcatga ctatgctaaa aagttgtcaa
     9061 atcaggaatt tctagccttg attgaccgtt accagctaga ccctgacctc aaaaactggg
     9121 gcaataatgt ctggcatggt atggtcggaa tttacaaaat tcaggaagat ttggatttgc
     9181 atgattctga aattctgcga gccattgaaa ttcatacagt cggagctggt caaatgacag
     9241 acctagataa ggtcatctac gtcgcagact atatcgagca caatcgagcc tttcctggag
     9301 tagatgtggc gcgtgagatt gcaagtctat cgctcaataa ggcggtggcc tacgaaacag
     9361 ctcgtaccgt ggagtatcta gctcatcagg gattccccat ctatccccaa acccttgaaa
     9421 cctataacgc ctttgtgcac tatttgaaag aggactaaat gaagacggct tttataatca
     9481 ttgatgttca gaatgtttta gtagaaactg ggttccagac aaaaagtcta ttggaaaaaa
     9541 tttcttattt acaaaaccag gctagaagca agaatattga aattatctat gttcaacata
     9601 ttgagaattc tgaagctcaa acatcagaag attggcagtt atctgcgctt ttaaatcgaa
     9661 aacctgctga aaaggtcttt cagaagaagt ataacagtat tttcaaagaa actggcttaa
     9721 aagaatactt ggataaacag gggattgaaa aattagtttt atgtggtatg cagacagaat
     9781 attgtgtgga tacctctgtc aaggttgcct ttgaatatgg ctatcagctt attgttccag
     9841 aaggtgctgt cacaaccttt gatggggatg acattccagc agaaacgatt aatgaatttt
     9901 atgaggacat ttgggaggag cactttgcag atgtcctaga ttacaaacat attttctaaa
     9961 aagaggatta aatgaacgaa aaagaattac tagaactagt cgtgaaagcg gctgatgaga
    10021 aacgtgcgga ggatatcctc gcacttgatg tacaagattt gactagtgtg acggactact
    10081 ttgtcatcac tagctcaatg aatagccgtc agttggacgc tatcgcagct aatatccgtg
    10141 aaaaagtagc tcaagcgggc tttaaaggta gccatgtcga aggcgatgca gctggaggct
    10201 gggtcttact ggacctcggt gctgttgtcg tgcatatctt ttcagaagaa atgcgtgccc
    10261 attataatct agagaagcta tggcatgagg cgaattcagt agatatttca gaagctcttg
    10321 cttagaagat gaactcagtt gtagtcaact gggtttcttt gcttatttta gaaaaattga
    10381 tagaaaggta aagggctagt ggtgtttacc atggagctct tagtatcatg attatggcga
    10441 cttatgaaac ctttgcggcg gtctatgatg cggtcatgga cgatagttta tacgacaaat
    10501 ggacgaattt ttctctgcgt catttgccta agaccaagga gaaaaagaaa ctcttggaac
    10561 tggcttgtgg gacaggaatt caatcagtgc gcttctctca ggctggtttt gatgtgactg
    10621 gacttgactt gagtgcggat atgttgaaga ttgcggagaa gagagcaact tcagccaagc
    10681 aaaagattgc ttttatagaa ggtaacatgc tgaatttgtc caaggcaggg aaatacgatt
    10741 ttgtcacgtg ttattcggac tctatctgct atatgcagga tgaggtggaa gtaggggacg
    10801 tctttaagga cgtgtacaat gcgctgaatg aagagggagt tttcatcttt gacgtgcact
    10861 cgacctacca gacagatgaa gtattccctg gctattccta ccatgaaaat gcggaagatt
    10921 ttgccatgct ttgggataca tatgaggacg aagctcctca ctccatcgtg catgagctga
    10981 ctttctttat caaggaggct gacggttcct ttagtcgcca cgatgaagta catgaggaga
    11041 ggacctatga gatcttgacc tatgatatct tactggaaca ggctggattc aagtccttca
    11101 aactctatgc agactttgag gataaggaac caacagaaac tagcacccgt tggttttttg
    11161 tggcgcagaa gtaggagatt agcatgacca tcacaggtat tatcgcggag ttcaatcctt
    11221 ttcataatgg ccataaatac ctgctggatc aggcagaggg actgaaaatt gttgccatgt
    11281 cagggaattt catgcagcgt ggagagcctg ctattgtgga taagtggaca agggcccaga
    11341 tggcgctgga aaatggcgca gacttggtag tggaattgcc ctttttagtc agtgttcagg
    11401 cagctgattt ctttggtcaa ggagctgtga atatcttgga tcgcttgggc attgatagtc
    11461 tagtttttgg gacagaggaa gttcgagatt atcagaaaat cgctgactta tacacagaga
    11521 aaggtgctga gatggagaaa tttgtggaaa atctgcctga ttccctttcc tatccccaga
    11581 aaacccaagc tatgtggaag gaatttgctg gtcttgattt ttcaggtaat acccccaatc
    11641 atgttcttgc tctggcctat gccaaggcgg ttgcaggacg aaatatcaag ctgcatccga
    11701 ttcagcgtca gggggcaggt taccattctg tgaataaaga tgtggacttt gcctcggcga
    11761 cagccctccg tcaacatcag aaggaccaag atttcttaga acgctttatg ccttctgttg
    11821 ccctatttga gcaggccagt aaggtgatct gggaagacta ttttcccttg ctccgctatc
    11881 aaatcttgtc aaatcccgac ctaaccacca tctatcaggt caatcaagaa atggctgtgc
    11941 gcattaaaga agctattaaa acagcccggt ctgtggaaga attggtcgag ttagtgacta
    12001 ccaaacgtta caccaaggcg cgtgtcagac gcctattgac ctatattttg atgcaggcta
    12061 gagaaaatgt cttgccagaa gtcattcatg tccttggatt tactgaaaaa ggtaggcaac
    12121 atctcaagtc tttgaaaggt caggtcagtc tagtcagccg aattggcaaa gaaccttggg
    12181 atgctatgac ccaaaaagca gaccagattt accaactagg aaatccaagt atagcagacc
    12241 agaattttgg aagagtgccg attagaatag aaacaaacta agtctaccga aaggtaggct
    12301 ttttgagatt ttttacgaat aatactcttc gaaaatcaaa ttcaaatcgc gtcaacgtcg
    12361 ccttgccgta ctcaagtaca gcctgcggct agtttcctag tttgctcttt gattttcatt
    12421 gagtataaat agatagaaaa gaaaatcttg tacaagttcc tgacaatttc tttcttttcg
    12481 tgtataatag tggaaaagag ctaaaacgag gtatggttat ggaagcagtc ctttactcaa
    12541 cattccgaaa tcatttaaag gactacatga agaaggtaaa tgatgaattt gagcctttga
    12601 cggtggtcaa taaaaatcca gatgaggaca ttgtagtcct ttcaaagagt gagtgggata
    12661 gtatccaaga aaccctgaga attgctcaaa ataaggaact ttctgataag gttttgcgag
    12721 gaatggctca agttcgtgct ggaagtactc aggtccatgt tattgaggag taagaaatgc
    12781 tgctcaagtt tacagaagat gcctgggcag attattgcta ctggcaaaat caggataaga
    12841 aaacgttaaa aagaatcaat aaactaatca aggatattca acgtgatccc tttacaggaa
    12901 taggtaaacc agaaccactc aaatatgatt accaaggagc ctggtcacgg cgtattgatg
    12961 cagaaaatcg cttgatttat atgatggatg gagatagcgt ggctttcttg tcctttaaag
    13021 atcattacta agtctattga aaggtaggct ttttctcaag tctctactaa actactattt
    13081 ctaaacaaca agtttatttt tgcaaatgtg ttccaaattc cccaaaacat attctatttt
    13141 aggtttgtga aaatcacttt tttatggtag aatgtaaaag aatgtatgtc attcggaata
    13201 acaataaaat gaggtaaaaa catggaaatc atgtcgcttg cgattgctgt ttttgccgtc
    13261 atcattggtt tagtcattgg atatgtcagc atctcagcta agatgaaatc atctcaggaa
    13321 gctgcagagt tgatgctttt aaatgctgaa caagaagcaa ctaatttacg tggacaagct
    13381 gagcgtgaag cggatttact tgttaatgaa gccaaacgtg aaagcaagtc tcttaaaaaa
    13441 gaagcactat tggaggccaa agaagaagcc agaaaatacc gtgaagaagt ggacgctgaa
    13501 ttcaaatcag aacgtcaaga actcaaacaa atcgaaagtc gtttgacaga gagagctact
    13561 agccttgacc gtaaggacga caatttgacg agtaaagaac aaacacttga acaaaaagaa
    13621 caaagtattt ctgatagagc gaaaaacctt gatgcgcgtg aagagcaatt agaggaagtc
    13681 gaaagacaaa aagaagcaga actagagcgt attggtgctc tgtctcaggc agaagcacga
    13741 gatattatct tggctcagac agaggaaaac ttgaccaggg agattgccag tcgcattcgc
    13801 gaagctgagc aagaggtcaa ggaacgttct gacaaaatgg ccaaggacat cttggttcaa
    13861 gctatgcaac gtatcgctgg tgaatatgta gcggagtcaa caaactcaac ggttcatctg
    13921 ccagacgata ctatgaaggg acgcattatt ggtcgtgaag gtcgtaacat tcgtaccttt
    13981 gaaagtttga caggggtcga tgtgattatc gacgatacac cagaagtggt gaccttgtca
    14041 ggatttgatc cgattcgtcg tgagattgcc cgtatgacta tggaaatgtt gctcaaagat
    14101 ggtcgtatac atccagctcg tatcgaagag ttggttgaga aaaaccgtca agagattgac
    14161 aataagattc gtgaatacgg tgaggctgct gcctatgaaa ttggtgcgcc aaaccttcat
    14221 ccagacttga tgaagattat gggacgtttg cagttccgta cttcatatgg acaaaatgtt
    14281 ttgcgccatt cgattgaggt tgctaagttg gctggtatca tggcgagcga acttggtgaa
    14341 aatgcggctc ttgcccgtcg tgctggattc cttcacgata tcgggaaagc cattgaccat
    14401 gaggttgaag gtagccacgt tgaaatcggt atggaattgg cccgtaagta caaggaaccc
    14461 ccagttgtgg tgaatacgat tgctagtcac cacggagatg ttgaagctga gagcgtgata
    14521 gcagttatcg tcgctgcagc agatgccttg agcgcagccc gtccaggtgc tcgtagtgag
    14581 tctcttgaaa gctacatcaa gcgtctccat gatttggaag aaattgctaa cggctttgaa
    14641 ggagtgcaaa ctagctttgc ccttcaagca ggacgtgaaa ttcgtatcat ggtcaatcca
    14701 ggaaaaatca aggacgacaa agtcacaatc ttggctcaca aagttcgtaa gaaaattgaa
    14761 aacaatctcg attatccagg aaatatcaag gtaaccgtga ttcgcgagct tcgtgcagta
    14821 gattatgcta aataaataag aaagagcagt tgaaaaatta ctgctttttt gttacactag
    14881 atagaaagac tgtaaaggat aatctggctt tttgccatta ttctagagaa atgttatttc
    14941 acagattgac taaaaggaga cacaatggca gaccgaggct tactaatcgt tttttctggt
    15001 ccttcagggg ttggaaaagg aacggttaga agagagattt ttgagagttc tgaaaaccaa
    15061 tttcaatact ctgtatcgat gacgacacgc gcacaacgtc ctggagaagt ggacggtgtc
    15121 gactatttct tccgtactcg tgaagaattt gaagagctga ttcgtcaagg acagatgttg
    15181 gaatacgcag aatatgtcgg taactactat ggaactcctc tgacctatgt caatgaaacc
    15241 ttggacaagg gaatcgatgt tttccttgaa attgaagttc agggtgctct tcaggtcaag
    15301 aaaaaggttc cagatgctgt ctttatcttc ctgacaccac cagatttgga tgaattgcaa
    15361 gatcgcttgg taggtcgtgg aacagatagt gcagaagtga ttgcccaacg aatcgaaaag
    15421 gccaaggaag aaattgccct catgcgtgag tatgattatg ccattgtcaa cgatcaggtg
    15481 cccctagctg ctgaacgtgt caaatgtgta attgaagcag aacacttctg tgtggatcgt
    15541 gtcattggtc actatcagga gatgttacca aaatctccaa ctacccgata aaatttagaa
    15601 aataggtaca agcaaatgat gttaaaaccc tctattgata ccttgctcga caaggttcct
    15661 tcaaaatatt cactcgtaat cttggaagca aaacgtgccc acgaattgga agcaggtgcc
    15721 ccagcaactc aaggtttcaa gtctgaaaaa tcaactcttc gcgctttaga agaaatcgaa
    15781 tcaggaaacg ttacaattca cccagatcca gaaggaaaac gcgaagcagt gcgtcgccgt
    15841 atcgaagaag aaaaacgccg caaagaagaa gaagaaaaga aaatcaaaga gcaaattgct
    15901 aaagaaaaag aagatggtga aaaaatttaa ggttgggggg actcaatctt attttttcta
    15961 ttgcaagaat gtactgacaa ggaggaggtg agaagatggc cctagctaag attatcgtag
    16021 atgtgccctt gatgcagacg gaccagccct atagttacag gattccggag gaatttgagg
    16081 gaatgctgga agttgggatg cgggttcatg tgccttttgg taagggtaat cgcctgattc
    16141 aagggattgt tcttggtttg gagtcccaat cagatggaga agagatggag caagatttaa
    16201 aagatattgc agaggtgctg gatttttctc ctgttctcac gccagaacaa ctctggctgg
    16261 ctgaggagtt acgcaaatct gtcttctcct acaaaatttc tatcctcaag gccatgcttc
    16321 caggatttct gaattctagc tatgacaaga ttctctatcc tctggaaggc ttgagtcagg
    16381 aagaacgagt gcgcctgttt ggttcagaag attcgctagc cttttcttca ctagaccttg
    16441 ccaagcaagc tgaaatgatg cgtttgacta gaaaaggcct gcttggtctg gaatatcagg
    16501 cagtcgatca aaagaaggtc aagacccagt cttggtatga ggttgaccat gctcaattag
    16561 aaggtgttga gatttctaca cgtgccaaga aaaagttgga actgagagat tatctgctgt
    16621 ctcatccaga gagcgcttcc ttggctagct tgttagagtc ctactcgcga gagcaagtca
    16681 acttctttgt ggatcaaggt gctgttacca tagtccaaaa ggaagttcaa cgctcggctg
    16741 cttattttga aggaattgaa gcaagtagac ctttggagtt aaatccagaa caaagacagg
    16801 cgcgtgatgc ggttgtgagt tctattggca gttctcaacc tccctttcta cttcaaggga
    16861 ttacaggaag tgggaagacc gaggtttact tgcagattat ccaaggtgcc ctggataagg
    16921 gcaagacagc tattttgctg gtacctgaga tttccttgac tcctcagatg accgagcgtt
    16981 ttatagcacg ttttggggac aaggtagcca ttcttcactc aggattatcc aatggtgaaa
    17041 agtatgatga atggcgcaag gtggagcgtg gcgatgccca agttgttgtt ggtgccagat
    17101 ctgctatctt tgctcctctg aaaaatctgg gtgtcatgat tattgatgaa gagcatgaag
    17161 cggcttataa gcaggacagc aatccccgtt accatgccag agaggtagct attttacggg
    17221 ctcagtataa tcaagcaact ctggtacttg gatctgcaac gccgagctta gagagccggg
    17281 cacgtgctgg caaaggcgtc tatcaacact tacgtctaac ccaacgtgcc aatcctttgg
    17341 ctacaatccc tgaggttcaa gtgattgact ttcgagacta tatcggacaa aatgagacgt
    17401 caaactttac gcctcctttg ctagaggcta tccaagaccg tctggttaaa aaagagcagg
    17461 tggttctcat gctcaatcgc cgtggttatt ctagctttgt catgtgtcgg gagtgtggga
    17521 cggtggatac ttgtcccaac tgcgatattt ctctgacctt gcatatggat accaagacta
    17581 tgaactgcca ttattgtggt ttctcgaagg atattcctca ggtctgtcct aactgtaaga
    17641 gccacagtat tcgttactat gggacgggaa ctcagaaggc ttatgatgag ctagcagaac
    17701 tctttcccca agttcgcatt ttgaggatgg atgtggatac gactcgaaag aaaggcagtc
    17761 accaagcctt gcttgaccag tttgggcgag gggaagcgga tattttactt ggtactcaga
    17821 tgattgcaaa gggtttggat tttcccaatg ttaccctagt aggagttcta aatgcggata
    17881 cggccttgaa tctgcctgat ttccgttctt ctgagagaac cttccagctc ttgactcagg
    17941 tggcaggtcg agcaggtcgg gctgaaaaag caggtcaagt cttgatacag tcctacaatt
    18001 cgcagcacta tgctattcga tttgccaagg atcaagatta cgaaggcttt tatgcctatg
    18061 aaatgggaat cagacgacaa ctcggctatc caccttacta tttcacgatt ggtattaccc
    18121 tttctcacaa gaaagaagaa gaggttttca aacgtgccta tgaagtcatg aacattttgc
    18181 ggtcaggctt gtcagagacc agtcccattc tggggccaac gccaaaaccg attgcccgta
    18241 cccgcaacct ctatcattac cagattttaa ttaaataccg tttagaagat gagctggggc
    18301 cgaccctcaa ccaggtcttg gccttgactc aagaacggga aaatagtgag ctccgtctca
    18361 gcattgacca tgagccgcag caatttttat aagaaggaga agatatgaca aaactaatct
    18421 ttatggggac ccccgacttt tcagcaacag tcttaaaagg acttttgaca gatgaccgtt
    18481 acgaaattct agccgttgtg acccagccaa accgtgctgt tggtcgtaaa aaagttatcc
    18541 aagaaacccc agtcaagcag gctgccaagg aagcaggact atctatctac caacctgaaa
    18601 aattatctgg aagtccagag atggaagatc ttatgaagct aggagcagat ggaattgtga
    18661 ctgctgcttt tgggcagttt ctcccaagca aactccttga tagcatggac tttgctgtca
    18721 acgttcatgc ctccctcctt cctagacacc gtggtggtgc gcctatccat tatgccttga
    18781 ttcaagggga tgaggaagct ggtgtgacca tcatggaaat ggttaaggaa atggatgcag
    18841 gagatatgat ttctcgtcgc agcattccga tcacagatga ggacaatgtt ggcaccttgt
    18901 ttgaaaaatt ggcgctagtt ggtcgtgatt tgcttttgga cactctgcct gcctatattg
    18961 ctggtgatat caaacctgaa ccgcaggata cgagtcaggt taccttctct ccaaatataa
    19021 agccagagga agaaaaactg gactggaaca aaaccaatcg tcaactcttt aaccaaattc
    19081 gtggaatgaa cccctggcct gttgcccata ctttccttaa gggcgaccgc tttaagattt
    19141 atgaagccct accagtagaa ggtcagggaa atccaggtga gattctctct atctgcaaga
    19201 aagaattgat tgtcgcaacg gctgaagggg ctctatccct caaacaagtg cagccagctg
    19261 gtaagcctaa gatggacatt gcttccttcc tcaacggagt tggacgtaca ttgactgtag
    19321 gagaacgatt tggtgactaa agtagaaacg gctagaagtt tagctctagc agtgctagag
    19381 gatgtttttg tgaatcaagc atattcaaat attgccttaa ataaacacct caaggggagt
    19441 cagctctctg cagcagacaa gggcttagtg accgagctag tctatggaac ggtagccctt
    19501 aaactgactc tggaatggta cctatcccac tttatcgaag acagagacca gttagacagc
    19561 tggctctatg tccttcttct catgagtgcc taccaactcc gctatttgga caagattcca
    19621 gatcatgctg tggtcaatga agcagtggaa ttggccaaac tccgtaaaaa aggcagtgaa
    19681 aaattggtca acgctgtcct tcgccgtatc ttgcgtgaag gctggccaga tattgctagc
    19741 atcaagcgaa aaaacaagcg tgactccatt gcctattctc tcccagtttg gctagttgcc
    19801 aaactcaagg aagaatacgg agaggagaga gcaaaagcca tctttgaaag cctgttagtg
    19861 cgaaacaaag ccagtattcg tgtaacagac ctaagtcgaa aagaggaaat ccaagccttg
    19921 ttggaggcga ataattccct tttagcaacc actggtctgg ttaaggagca ggggcatttt
    19981 gcagggcata atttgtttgc gaatggagcc attaccatcc aagatgagtc cagtcagctg
    20041 gttgctccga cgcttgattt acaaggtgat gagcgagtgc ttgatgcctg tgcggctcca
    20101 ggtgggaaaa cagcccatat agcctcttat cttacgacag gtcaggttac tgctctggac
    20161 ttgtacgacc acaagttgga tttaattcaa gaaaatgccc aacgtctggg agttgcagat
    20221 cgggttcaaa ctcaaaaatt ggatgccaga aaggtgcatg agttttttga ccaggattcc
    20281 tttgataaga ttttggtgga tgctccttgt tcaggaatcg gtcttttgcg ccgaaaacca
    20341 gatatcaaat acaataaaga aacggcagat ttcgcgtcct tgcaggaaat tcagttagaa
    20401 atattaggta gtgtttgtca aatactaggc aaaggtggta taataactta tagcacctgc
    20461 actatcgtct cagaggagaa ttttcaagtc gttaaggcct ttttagagag tcatcccgag
    20521 ttcgagcagg taaaactaga acatgaatgt aaggatatca tgaaagacgg ctgtatcctc
    20581 attacacctg aattgtatgg aagtgatgga ttcttcatca gtcaatttcg caagatatcg
    20641 gattaggaag gaactgacac atggaaattt cattattaac agatgttggt cagaaacgaa
    20701 caaataacca agactatgtc aaccactatg tcaatagagc tggacgtacc atgattattt
    20761 tagctgatgg gatgggaggt catcgcgcag ggaatatcgc tagtgaaatg gcggtcacag
    20821 acctgggtgt agcttgggtt gatacccaga tcgatacagt caatgaagtg cgtgaatggt
    20881 tcgcccatta cctagaaatt gaaaatcaaa agattcacca gcttggtcag gatgaagctt
    20941 acagaggcat gggaactact ttggaagtcc ttgctattat tgataatcag gctatctatg
    21001 ctcatattgg tgattcgcgt atcggcttga ttcgtggaga agaataccat cagttgacga
    21061 gtgatcattc tttggttaat gaattgctca aggctggtca attgacacca gaagaggcag
    21121 aagctcatcc gcaaaaaaat attatcaccc agtctattgg gcaaaaagat gaaattcagc
    21181 ctgattttgg gacagttatc cttgagtcag gtgactatct cttgctcaat agtgacggct
    21241 tgaccaacat gatttcaggc agtgagattc gtgatattgt aaccagtgat attcctttag
    21301 cagataaaac ggagacactt gttcgttttg ctaacaatgc aggaggttta gacaacatta
    21361 cggttgccct tgtttctatg aacgaggagg atgaagaatg atccaaatcg gcaagatttt
    21421 tgccggacgc tatcggattg tcaaacagat tggtcgagga ggcatggcgg atgtctacct
    21481 agccaaagac ttaatcttag atggggaaga agtggcagtg aaggttctga ggaccaacta
    21541 ccagacggac ccgatagctg tagctcgttt tcagcgtgaa gcgagagcta tggcagatct
    21601 agaccatcct catatcgttc ggataacaga tattggtgag gaagacggtc aacagtatct
    21661 tgcaatggag tatgttgctg gactagacct caaacgctat atcaaggaac attatcctct
    21721 ttctaatgaa gaagcagtcc gtatcatggg acaaattctc ttggctatgc gcttggccca
    21781 tactcgagga attgttcaca gggacttgaa acctcaaaat atccttttga caccagatgg
    21841 gacggccaag gtcacagact ttgggattgc tgtagccttt gcagagacaa gtctgaccca
    21901 gactaactcg atgttgggct cagttcatta cttgtcacca gagcaggcgc gtggttcgaa
    21961 ggcgactgtg cagagtgata tctatgccat ggggattatt ttctatgaga tgttgacagg
    22021 ccatatccct tatgacgggg atagcgcggt gaccattgcc ctccagcatt tccagaaacc
    22081 cctgccgtcc gttattgcag aaaatccatc tgtacctcag gctttagaaa atgttattat
    22141 caaggcaact gctaaaaagt tgaccaatcg ctaccgctcg gtttcagaga tgtatgtgga
    22201 cttgtctagt agcttgtcct acaatcgtag aaatgaaagt aagttaatct ttgatgaaac
    22261 gagcaaggca gataccaaga ccttgccgaa ggtttctcag agtaccttga catctattcc
    22321 taaggttcaa gcgcagacag aacacaaatc aatcaaaaac ccaagccagg ctgtgacaga
    22381 ggaaacttac caaccacaag caccgaaaaa acatagattt aagatgcgtt acctgatttt
    22441 gttggccagc cttgtattgg tggcagcttc tcttatttgg atactatcca gaactcctgc
    22501 aaccattgcc attccagatg tggcaggtca gacagttgca gaggccaagg caacgctcaa
    22561 aaaagccaat tttgagattg gtgaggagaa gacagaggct agtgaaaagg tggaagaagg
    22621 gcggattatc cgtacagatc ctggcgctgg aactggtcga aaagaaggaa cgaaaatcaa
    22681 tttggttgtc tcatcaggca aacaatcctt ccaaattagt aattatgtcg gccggaaatc
    22741 ttctgatgtt atcgcggaat taaaagagaa aaaagttcca gataatttga ttaaaattga
    22801 ggaagaagag tcgaatgaga gtgaggctgg aacggtcctg aagcaaagtc taccagaagg
    22861 tacgacctat gacttgagca aggcaactca aattgttttg acagtagcta aaaaagctac
    22921 gacgattcaa ttagggaact atattggacg gaactctaca gaagtaatct cagaactcaa
    22981 gcagaagaag gttcctgaga atttgattaa gatagaggaa gaagagtcca gcgaaagcga
    23041 accaggaacg attatgaaac aaagtccagg tgccggaacg acttatgatg tgagtaaacc
    23101 tactcaaatt gtcttgacag tagctaaaaa agttacaagt gttgccatgc cgagttacat
    23161 tggttccagc ttggagttta ctaagaacaa tttgattcaa attgttggga ttaaggaagc
    23221 taatatagaa gttgtagaag tgacgacagc gcctgcaggt agtgtagaag gcatggttgt
    23281 tgaacaaagt cctagagcag gtgaaaaggt agacctaaat aagactagag tcaagatttc
    23341 aatctacaaa cctaaaacaa cttcagctac tccttaaaag cagatggata atcaaaatga
    23401 gtaatcaatc tttgtcatga tttcatggca aagatttttt ttgagtccag atttgtgata
    23461 gaatagaggg agttgataaa aggaggaaag catggaagaa tcaaaagaat taaatgccgt
    23521 cattgatgtg attatgctag cggggactat tctccttaaa agtggctcag aaatccatcg
    23581 tgtagaagat accatgattc gaatcgcgca ttcgcagggg attgtggatt gcaatgtcct
    23641 tgccatgcct gccgctatct ttttctctat tgaaaatacc aatatttcgc gcatgaagcg
    23701 cgtgacctcc tcttcttata acatcgaaaa agtctgcgat gtgaaccaga tttctcgtca
    23761 gctagttggg gggcagattg acttagaaac agcctttaag caattgacgg ccttgcaagc
    23821 tcaacccctt ccctatacta agttgcaggt aactctggct gcgaccttta gtgctccttt
    23881 cttttcagtt atgtttagcg gaaatatcta cgacgcactt ggtgcaggag tggcgacctt
    23941 atttggtttt gccttttccc tctatgtgga aaaatttatc cgaattccct ttgtgacagc
    24001 ctttgctgga gcctttgtct ttgggataat tgcccagttt tgggctcgct acacaggttt
    24061 tccttcaacg gcagatttga ttatagctgg tgcggtcatg ccgtttgtac caggtattgc
    24121 cttgaccaat gcggtccgtg atattatgac caaccacata aactctggta tgagtaagat
    24181 gtttgaatcc ctgctcatta ccctcgcttt aggggcagga acttctgtcg ccttggtatt
    24241 gatgaactaa tatgacacta acaacctttt tattacaagc agtagcaagt tttcttgcca
    24301 ttatcacttt tttaatcgta ctcaatgtgc aacggtctat gctcttacct ggagggattt
    24361 tgggcatgac tgtctggcta atctatctct tgctcaagga accgaccaat gtcattgtag
    24421 ctaccttcat tgcagccatt attggttctt gtgtcagcca gattttaagt attctttata
    24481 agacacctgc tgtggtcttt atcttggcca ttttggcacc gctggttcca ggttatctct
    24541 cctaccgaac aactgccttt tttgtgacag gggactataa taaagcactg gcaagtgcga
    24601 ccttggttgt catgttggct ttggtaatct ctattggaat ggctagcgga acagtgattc
    24661 tcagactgta tcattatata aaaacacatc gagtatcgta gactttacag aaataaaaga
    24721 attttctgaa aaatgagata aataaattaa caacgctttc tatatgtgcg agaataccgc
    24781 acttatgaag aaattgcgac tgattttggt atccacgaaa gcaacttact ccgtcggagc
    24841 caatgggttg aagtaactct tgttcaaagg tggtgttacg atttcaagaa ctcctctcag
    24901 ttctgaagac acggtaatga ttgatgcgac ggaagtaaaa atcaatcgcc ctaaaaaaaa
    24961 caattagcga atgattctgg taaaaagaaa tttcacgcta tgaaggctca agcgattgtc
    25021 acaagtcaag ggagaattgt ttctttggat atcactgtga actattgtca tgatatgaag
    25081 ttgttcaaaa tgagtcgcag aaatatcgga caagctggta aaatcttggc tgacagtggt
    25141 tatcaagggc tcatgaagat atatcctcaa gcacaaactc cacgtaaatc cagcaaactc
    25201 aagctgctaa cagttgaaga taaagcctat aaccatgcgc tatctaagga gagaagcaag
    25261 gttgagaaca tctttgccaa agtaaaaacg tttaaaatgt tttcaacaac ctatcgaaat
    25321 catcgtaaac gcttcggatt acgaatgaat ttgattgctg gcattatcaa tcatgaacta
    25381 ggattctagt tttgcaggaa gtctactact ttccttattg tctgtaaatc tactgacctt
    25441 gttgtttatc ccagtcatgg tttctagttc gggctcagag tttcaaagtg gatggcaaga
    25501 gcatcaattg attgctgaga aggttagtaa aacacttgat aagacatttg ataaggatgt
    25561 cagagaaatt ccgaccagtc agttttatca aaaatttgta gatgagatgg gaaggactta
    25621 ctcaggaaat ttgatcctcc aggagctgat aactgtgaat ggagcttata aagctactta
    25681 tatcggtgaa ctctctagca actaatcatt ctttaaaatg atgaccaata agaggcttga
    25741 tttggtgaat caagtctttt ttctctcttt tactgccatt tgtgataaaa tagtatagaa
    25801 cgatttttta catgaatgat aaaacagagg taaatatgac aatcggtatt gataagattg
    25861 gttttgcgac cagtcaatat gtcttgaaat tacaagactt agcagaagcg aggggaattg
    25921 accctgaaaa attaagtaaa ggactcttac tcaaggaatt gagtattgcg cccctaactg
    25981 aggacatcgt gaccttggcg gccagtgcta gtgactctat tttaactgag caagaaagac
    26041 aagaagttga catggtcatt gtggcgaccg agtcaggaat tgaccagagt aaggctgcgg
    26101 ccgtctttgt gcatggcttg ctgggcatcc agccctttgc tcgtagtttc gagattaaag
    26161 aagcctgcta tggggcgact gctgccctcc attatgccaa attgcatgtg gaaaattctc
    26221 cggagtccaa ggtcttggtc attgcaagtg atattgccaa atacggtatt gaaactccgg
    26281 gagaacccac tcagggtgcc ggaagtgtgg ctatgttgat tacacaaaat ccacgcatga
    26341 tggcctttaa taatgacaat gtagctcaga cccgtgacat catggatttc tggcgaccaa
    26401 attactcgac aactccttat gtaaatggtg tctattctac ccaacaatac ttggatagtt
    26461 tgaaaacgac ttggcttgaa tatcaaaaac gctaccagct tactttggat gattttgcgg
    26521 ctgtttgttt ccacttgcct tatcctaaat tagcgctaaa aggcttgaaa aaaatcatgg
    26581 ataagagcct gcctcaagag aaaaaagacc tcttacaaaa gcattttgac cagtctattc
    26641 tctacagtca aaaggtgggg aatatctaca caggttcact tttccttgga cttttgtctc
    26701 tcttggaaaa tacagatagc ttgaaagctg gggataaaat cgccctttat agttacggaa
    26761 gtggagctgt ggctgagttc ttcagtggtg aattggttga aggatatgaa gcttatttgg
    26821 ataaagaccg cttgaacaag ctcaaccaac gaactgtctt atccgttgca gactatgaaa
    26881 aggtcttttt tgaggaagta aacttggatg aaacaaactc tgcccagttt gctggctatg
    26941 aaaatcaaga ttttgccttg gttgaaattc tcgaccacca acgccgttat agcaaggttg
    27001 aaaaataatg aagataagtt ggaatgggtt ttctaaaaaa tcataccaag agcgcctcga
    27061 gctgttaaaa gctcaggcgc tccttagtcc tgagagacaa gctagtctgg agaaggatga
    27121 acagatgagt gtgactgtgg cagaccagct gagtgagaat gtagtgggaa ctttttctct
    27181 gccttattcg ctggttccgg aggtacttgt caacggtcag gaatacaccg ttccctatgt
    27241 gacagaagaa ccctctgtgg ttgcggcggc cagctatgcc agcaaaatca tcaagcgtgc
    27301 aggtggtttt actgcacaag tccatcagcg ccagatgatt gggcaggtag ccctttatca
    27361 agttgctaat cctaaactag cgcaagagaa gattgccagc aagaaagcgg agctcttgga
    27421 gcttgccaat caagcctatc cttctatcgt taaacgtggg ggtggggcgc gtgacctgca
    27481 tgtcgagcag ataaaaggcg aaccagactt tctcgttgtt tatattcatg tcgataccca
    27541 ggaagccatg ggtgccaata tgctcaacac catgctggaa gccttgaaac cagtcttaga
    27601 agaactcagt cagggacaga gtctcatggg aatcctgtcc aactacgcga ccgattctct
    27661 ggtgactgca agctgtcgca tggcctttcg ctacttgagc cgccaaaagg atcaaggacg
    27721 agagattgcg gagaaaattg cgttggctag tcagtttgcg caggatgatc cttaccgagc
    27781 tgctactcat aataaaggaa tttttaatgg tattgatgcg attttgattg ccactggtaa
    27841 tgactggcgt gccatcgaag ctggggccca tgcctttgcc agtcgagatg gacgctatca
    27901 aggtcttagt tgctggacgc tggaccttga aagagaagaa ttggtcggtg agatgaccct
    27961 gcccatgcct gtagcgacta agggtggctc tatcggcctc aacccacgtg tagctctcag
    28021 tcatgatcta ctaggaaatc cttctgccag agaattagcc cagattatcg tgtctatcgg
    28081 tcttgcccaa aattttgcag ccctcaaagc cttggtaagt acgggcatcc agcaaggcca
    28141 catgaaacta caggccaaat ccctagctct cctagctggg gctagtgaat ctgaagttgc
    28201 tcccctagtc gagcagctta tcgcagataa aacctttaac ctagagacag cccagcgcta
    28261 tctcgaaaat ttaagatcat aaaaaactca gacgaatcgg tctgagtttt cttgtgttta
    28321 aatacttttt cctggtaata gtgtaactgg taagaagtaa ccagttgtgg tgacttcctt
    28381 gccttcaatc ttttgcaaga gaagatcaat agtgagacaa gcaatctctt ccaaaggttg
    28441 cttgatagta gccaattgag ggtagtaatt ttcgataaag taggtcccat catagccgat
    28501 gaccttgagc tcttttggga cagaaatgcc caattcttga gcgattttaa tgaccagaat
    28561 agctgtcaaa tcatccgaag caaaaatggc atctggtttt tcccgggtca agatattctt
    28621 gatttccatt tcttttctga cgggagaaaa gtcactggaa acattgataa taggagcttt
    28681 tgggagtacg gatgcaaaac cagcgtggcg cagtccggtt ggcgaattgg aattgtcatt
    28741 ccctgtaatc atgatgatag actgggcacc tgtcttgacc aaggtttggg cagcaagaac
    28801 cccaccagca tagttgtcag aggagacgac agggatgtct ggcgataggt ttcggtcaaa
    28861 ggaaataatc ggcgctgtca cacgattgta gtcttcgatt cctaggttgt gactaccaga
    28921 aatgatgccg tccacctgat tggcttccaa catttcgatg tattcacgtt ccttctcaga
    28981 atcatgttca ctgttgcaga tgatggtctt gtaaccattt ttgaagagtt ggtgttccaa
    29041 tttatcaatc aattctgcat agaaaacatt ggaaatattg gggaaaatca agccgattaa
    29101 cttagctgat tttccttgca gactacgagc caggttgttg ggtttatagc ccaattctcg
    29161 catggcttca ttgacttttt ggatggtttt ctcagataga tacccttttt tattgataac
    29221 ccgagaaacg gtagtaggac tgacgcctgc aagtttggcg acatcagtta gttttgcgac
    29281 cataatctaa ttcatagtaa gttccagttg ggtttccaga tttgatcagg ataccatttt
    29341 ggtccgcatg tgggaagaca cgaccagaaa atactttttc tcctttattg atgaaaattt
    29401 caaagacaga gttatcgatg aagattgtag cagtagtagc ctgattctcg atagggcaag
    29461 aacgagttgt cccaaattct tgggcatact gttctccagc ctggctacga tccactgtca
    29521 cttgaccgtt tacaaggtca aagttgattg aaagtccctt accttcttta tcagcaagta
    29581 agacaatctc gctctggcta ttagcttcca agttgagttc aagttcgtaa gtgttcttgg
    29641 tttgggaacg gtttgagaag gcttcttcag aagcacgaag gtccttaata gcagcgactg
    29701 gatactggta gagcttgtcg tctttgatag tgagttcctt gaccaaagag aaggttcctt
    29761 ggtggtcaaa acggtcagat gggtaagaaa catctggcaa accaagccag ctaactgcta
    29821 gagcacgccc atcaggagcg ttgaaggctt gagttgcata ggcttcgaaa ccgtaatcca
    29881 tgttttgaag ttgagacaca tctaccattt tggcattttt agggtcaaag gaagccccaa
    29941 tcttatacat atttggaaag atattatcgt agtctagaac tttcttatcc aatccttgtg
    30001 gacagtagag aaggacaggt tgttcctcta caaagaccag attaggacat tccatcatgt
    30061 aggcagtacg gtcgttagca aagtcaaggt cgccaactgc ttgccagttt gtgtagtcgt
    30121 tattgacagc cttgtagaga cgaacgaaac cttttttctc caagtcctgt ccaccgacga
    30181 cagcatagta ttgaccttta aagttaaaaa tttgtggatc gcggaagtgg tcagtagagt
    30241 ctgctggctg gtcaatcaag atcttgtcaa tctttgtaat cttaccctcc ttgtccatca
    30301 aagcaccgat ctggtatggg tgacggatcc agttttcatc gcgaacattt cctgtataaa
    30361 ataggaataa gttatcgcca aattgcatgg cagaaccaga gtaggcaccg tggctatcta
    30421 atggagtatc tggtaaaact ttgattccag tttctttaaa gtgaaccaaa tcatcacttt
    30481 ctagctgtgc ccaagatttt aaaccgtggg ctgcaccaaa aggaaaattc tggtaaaaga
    30541 ggatccactt gccatcaaag taagaaaagc catttgggtc gttgagaagt cctgtttttg
    30601 gctcaacatg gtaatgagta tgccatggag attgtgccat attttccttt atatgttgaa
    30661 tttcttcttg cgtccaatct tgataaagtc tgtaacgacg ctcagttgtc cattccattc
    30721 attcctccaa aaatcttatc acttttaata gtaactgttt tcgataaaaa atgcaagcct
    30781 tttatgttaa aaaagaggaa aaactgtcaa aggattatca taaaataaat acaggaaatc
    30841 aatcaaattt ttacgaaaat gtgaaagata atgaaataaa agacttttta accaaggttt
    30901 caaacttatt tttcaaggaa ttcctgatga aacagtcaaa aacaatcaat ctaaagcttg
    30961 cccactaagt ggatagaata tttttctgca aaacgcttga catattttta aaacatgata
    31021 aaataatagt cgtaagggcg aataaaatcg ctttcaaaca agaacaaaat gttatataag
    31081 gagatttttg caaatgaaca atcaggaaat tgcaaaaaaa gtcatcgatg ccttgggcgg
    31141 acgtgaaaat gtcaatagtg ttgcccactg tgcgactcgt ctacgtgtca tggtcaaaga
    31201 tgaagagaaa atcaataaag aagtgattga gaacttggaa aaagttcaag gtgctttctt
    31261 taactcaggg caataccaaa ttatctttgg tacaggtaca gttaacaaaa tgtacgatga
    31321 agttgttgta cttggcttac caacatcatc taaggatgac atgaaagcag aagttgctaa
    31381 acaagggaac tggttccaac gtgctatccg tacttttggt gatgttttcg ttccaatcat
    31441 cccagttatc gtagcgacag gtctcttcat gggtgtgcgt ggtcttttca acgctcttga
    31501 aatgccactt ccaggtgact ttgcaactta cacacaaatc ttgacagata cagccttcat
    31561 catcttgcca ggtttggttg tgtggtcaac cttccgtgta tttggtggaa atcctgccgt
    31621 tggtatcgtt cttggtatga tgcttgtctc tggctcactt ccaaacgctt gggcagttgc
    31681 tcaaggtggt gaagtaacag cgatgaactt ctttggtttc atccctgttg ttggtttgca
    31741 aggttccgtt cttccagcct tcatcatcgg ggttgtcgga gctaaatttg aaaaagctgt
    31801 ccgcaaggtt gttccagatg tcattgacct cttggtaaca ccattcgtga cacttttggt
    31861 catgtctatc cttggactct ttatcattgg accagttttc cacgttgttg aaaactacat
    31921 ccttattgct acaaaagcga ttcttagcat gccatttggc cttggtggtt tcttgattgg
    31981 tggggttcac caattgatcg tcgtgtcagg tgtgcaccac atcttcaact tgcttgaagt
    32041 gcaattactt gctgctgacc atgctaaccc attcaacgct atcatcacag ctgctatgac
    32101 agctcaaggt gctgctactg ttgcggttgg tgttaaaaca aaaaatccaa aactgaaaac
    32161 acttgctttc ccggctgctc tttctgcctt cctaggtatt acagagcctg ctatcttcgg
    32221 ggtgaacttg cgcttccgta aaccattctt cctttcattg attgctggtg caatcggtgg
    32281 tggattggct tctatccttg gacttgctgg tactggtaat ggtatcacca tcatccctgg
    32341 tacaatgctt tatgttggta acggacaact tccacaatac cttcttatgg tagctgtatc
    32401 atttgccctt ggttttgctc ttacttacat gtttggttac gaagatgaag tagacgcaac
    32461 tgcagctgca aaacaagctg aagtggctga agaaaaagaa gaagttgcgc cagcagctct
    32521 tcaaaatgaa acacttgtaa ctcctatcgt cggtgatgtt gtcgctcttg ctgatgtcaa
    32581 tgacccagtc ttctcaagtg gagctatggg acaaggtatc gctgtgaaac caagccaagg
    32641 cgtggtctat gcaccagctg atgctgaagt ttcaattgcc tttccaacag ggcacgcttt
    32701 tggtttgaaa acaagaaatg gtgctgaagt tttgattcat gttggtattg atactgtatc
    32761 tatgaacggt gacggttttg aaacaaaagt tgctcaaggt gataaggtga aagttggcga
    32821 tgttcttgga acatttgact caaacaaaat cgctgcagct ggacttgatg atacaacaat
    32881 ggttatcgtt acaaatacag gtgactacgc ttcagtagct ccagtcgcaa caggttcagt
    32941 tgctaagggg gatgctgtga tcgaagtgaa aatctaatca atcctctcta atgtgaaaac
    33001 gaacaaatga catatttgtt cgtttttatt agatagtaag atttacagag gaaaatctaa
    33061 aaaatagaga catttagact ttcgaagtat gctataataa agaaaataaa aacaagaggt
    33121 ttatcatgac aaaattatat ggaagcttgg aagcgggcgg tacaaagttt gtctgtgctg
    33181 tcggtgatga aaactttaac gttgtagaaa aaacacaatt tccaacaaca actccaatcg
    33241 aaacaatcga taaaaccatt gagttcttct caaaattcga taaccttgct ggtcttgcag
    33301 ttggttcatt tgggccgatt gatattgaca aaaactcaaa aacttatggc tttatcacga
    33361 cgactccaaa accaaactgg gcaaatgtgg acttgcttgg tgcccttcgt cgcgccctaa
    33421 atgtgccaat gtacttcaca acagacgtaa acagctctgc ttacggtgaa gtggttgccc
    33481 gtaacaatgc tggtggtcgt atcgaaaact tggtttacta cacaatcggt acaggtatcg
    33541 gtgcaggtgt catccaacgt ggtgagttta tcggtggtgt gggtcaccct gaaatgggtc
    33601 attattatgt tgctagacac ccaatggata ttgaaaaaga gtttaagggt gtttgtcctt
    33661 tccataaggg atgtctagaa ggttatgcag ctggtccaag tttggaagct cgtacaggtg
    33721 tacgtgggga aactattgaa ctcaacaacc ctgtttggga tgttcaagcc tactatatcg
    33781 ctcaagctgc ggttaatgcg acagtgactt tccgcccaga cgtgattgtc tttggtggag
    33841 gggtcatggc tcaacaacat atgctggacc gtgtccgtga gaaatttaca tctcttctta
    33901 atggttacct accagtacca gatgtgcgtg actatatcgt gacgccagca gtcgcaggaa
    33961 atggttctgc cacacttggg aactttgttc ttgcaaaaga agtttcaaaa taaagcacaa
    34021 aatccgcttg ggaaaccaaa cggatttttt acgtgtcaaa gcatttgcca gaaaaagtca
    34081 ataatatagg tcagaccgta ggtataaacc acgagggtaa agggtttggt cagaatgatg
    34141 atggtcatgt agcgcttgaa actcatcttg gtcagggcag ccagcataca gagaaagtca
    34201 gctgggctaa tgggccaaat catcataaaa ataaagaagc ggtcaaaacg attgccctta
    34261 tctagccagc cgatgtactt gtcgtaggtg cgcttgctga cgacagactg gacaaaggca
    34321 gctccgtata ggcgcactag ataaaagata atggcacagc caatcacgat gccgatatag
    34381 ttgtagatag tcccgatgat gtgcccgtag ataaagaccc cagccaccga ggtcaaggcc
    34441 cctggaatga tagggacgac agtctgtaaa atctgtaaaa agataaagag aggtggaccc
    34501 cagatgcctg cctgctggat aaaggcagag agggtttcct tggattgtaa aatcccagcc
    34561 tgataagccc aaatacagaa aatcaaactc ccaaccccac cgacaatcga tgagatattg
    34621 ataactcgct gcagaagggg agaaacagct ttcatttgtt tatcctgtga catgtaaact
    34681 cctcatagat agtatatttc tactatacca tattttggag gagaaagggg gaatgagtct
    34741 tttttgataa ggaatagaaa gtaaatagcc cttcgagact tagaataggt ctgtcaacta
    34801 aaggttatat gcattctagg tttcgaataa tcgcaattcc ataaatttaa aagtattcta
    34861 agtttcgaat agcttatctg ggataatttt gaggcattcg cgctttcgaa tagtcatttt
    34921 ccctaaagtt tatatgtatt ctgaagctag aaagactaaa atataaaagt agtaagagtc
    34981 tctctctgat ggacgtaatt tatggctagt atgaatcctt tgaattgtta gttaatttta
    35041 atattaatca gttctgaaat aattactaaa tatagttaga tggtgagtta attattgcta
    35101 aatttcaagt tcaagttagt catccagaag tcttctctgg gggacttgta gttcaagcat
    35161 tttttaggat agttgttaat ccacttttcg ataaatgcga cttcctttgt agttgttttc
    35221 ttagttccct gaggtaacca tctatgaatg agcctgttgt gattttcatt agatcctata
    35281 gtgatgtgca taatagatat agcagattga aactagaata gtatacatct acttctaaaa
    35341 cattgttaga aatcaatttg actgtcctga tcaatttgtc ctgtttttat ttcattttac
    35401 tatataatcc ttagaaaaca tatcggacaa gcggttgaat tccgttccgt ccattagtag
    35461 ataaaggatt actccttctt gaaatgacag atgaacttgt ttcttataaa aatgttgtct
    35521 gaaactatta gcctttttcc agaagtttta gaggaagaaa actttacgag gaaaaaggag
    35581 ttactcaaat aacaattcag gattaaaaat agacagttga ggagcggaag gtataaatta
    35641 agtttgctac tgtataatgg atttatcact aatactcttc gaaaatctct tcaaaccacg
    35701 tcagcttcgc cttgccgtag atatagttac tgacttcgtc agttctatcc acaacctcaa
    35761 aacagtgttt tgagctgact tcgtcagttt tatctgcaac ctcaaagctg tactttgagc
    35821 agcctacggc tagcttccta gtttgctctt tgcttttcat tgagtataaa agtgctccag
    35881 gccatatttt acacagcaat agtcttctaa aaatggacaa aaacattgta aaggctatca
    35941 aaaaggagta taatgagtgc aagaaatttc ggaggtgaaa gatgctagaa gtaagaagtc
    36001 tagagaaaag ttttggctcc aagcaagttt tgtttggtat tgactttcaa gcgcgaccag
    36061 gtcgtatttt gggactagtc ggaaaaaatg gtgctggaaa aacaacgatt ttccatagta
    36121 ttttgaaatt cctagaatat cagggagaaa tcggtctgga tggtcaggat attcgtcagg
    36181 agacctatgc tcggattggt tatctgcctg aagaacgcag tctcatgcct aaattgacag
    36241 ttcttgaaca agttcgctac ttggcgactc taaaaggcat ggatgccaaa gaagtcaaag
    36301 aaaaactccc tcaatggatg aagaggttgg aagtgaaagg aaagctgaca gataaaatca
    36361 agagtctgtc aaaaggaaat cagcagaaga ttcagctcat tattactctg attcatgaac
    36421 cagacctgat tatcttggat gagcctttta gtggattgga cccagttaat acagaattgc
    36481 tcaaacaagt catttttcag gaaaaagagc gcggagcaac cattatcttt tctgaccatg
    36541 tcatgaccaa tgttgaggaa ctttgtgacg atattctgat gatccgagat ggccgtgtgg
    36601 tcttgcacgg accagttcag gatgtccgca atcaatacgg gaaaacgcgt ctctttgttt
    36661 caagtgaacg aagcaaggaa gaattggaaa atcttcctca tgtcaaacag gtgagcttga
    36721 ccaaacaagg cagttggaaa ttgattttgg aggatgagag cgctggaagg gaactcttcc
    36781 caatcttgac tcaaggtcaa tatatcgcaa catttgacca acaagcgcca actatcgatg
    36841 aaatctttaa actagaatca ggagtggaag tatgagaaat atgtgggttg taatcaagga
    36901 aacctatctt cgacatgtcg agtcatggag tttcttcttt atggtgattt cgccgttcct
    36961 ctttttagga atctctgtag gaattgggca tctccaaggt tcttctatgg ctaaaaataa
    37021 taaagtggca gtagtgacaa cagtgccatc tgtagcagaa ggactgaaga atgtaaatgg
    37081 tgttaacttc gactataaag acgaagcaag tgccaaagaa gcaattaaag aagaaaaatt
    37141 aaaaggttat ttgaccattg atcaagaaga tagtgttcta aaggcagttt atcatggcga
    37201 aacatcgctt gaaaatggaa ttaaatttga ggttacaggt acactcaatg aactgcaaaa
    37261 tcagcttaat cgttcaactg cttccttgtc tcaagagcag gaaaaacgct tagagcagac
    37321 aattcaattc acagaaaaga ttgatgaagc caaggaaaat aaaaagttta ttcaaacaat
    37381 tgcagcaggt gccttaggat tctttcttta tatgattctg attacctatg cgggtgtaac
    37441 agctcaggaa gttgccagtg aaaaaggcac caaaattatg gaagtcgttt tttctagcat
    37501 aagggcaagt cactatttct atgcgcggat gatggctctg tttctagtga ttttaacgca
    37561 tattgggatc tatgttgtag gtggtctggc tgccgttttg ctctttaaag atttgccatt
    37621 cttggctcag tctggtattt tggatcactt gggagatgct atctcactga ataccttgct
    37681 ctttattttg atcagtcttt tcatgtacgt agtcttggca gcattcctag gatctatggt
    37741 ttctcgtcct gaggactcag ggaaagcctt gtcgcctttg atgattttga ttatgggtgg
    37801 tttttttgga gtgacagctc taggtgcagc tggtgacaat ctcctcttga agattggttc
    37861 ttatattccc tttatttcga ccttctttat gccgtttcga acgattaatg gctatgcggg
    37921 gggagcagaa gcatggattt cacttgctat tacagtgatt tttgcggtgg tagcaacagg
    37981 atttatcgga cgcatgtatg ctagtctcgt tcttcaaacg gatgatttag ggatttggaa
    38041 aacctttaaa cgtgccttat cttataaata gaagagcctt gcgaaagcga ggtttttaaa
    38101 gatgaaaagg atggaatcac gaacctaatt atgtacacat tatgtaaaca ggttgcttga
    38161 aaactcaatt gtatagtgaa ctgaatctgg aataggataa tattacttct aaaacattct
    38221 tataaattga tttgaattcc aaaatcccat cgttccgttc ttatttcatt ttgcgatata
    38281 gtgaaaggaa ataagtcagc tcacaaaaaa cgcataatat caaggatttt taacacttga
    38341 tactatgcgt tttctaattt taaagacttt ttgcctggtc tcttttgttc tatgagtatg
    38401 ttacatatct aggtaaaaat tatttaaagc aaattaacct tatttctcaa gatgtagtag
    38461 gttccgagat aaaagatagc tatgaatatg agttctttaa caatggctat acctgctccc
    38521 atatagaaat ggtcattgag tcctaccagt gaattgacat agaaattaga actaagattg
    38581 aagaaaagtt caataaatcc aatgacgatt tggataccaa tgtaggctgc aacagcgagt
    38641 gctgtacggt attcattgaa aagctgtcca atggaaatag ccaggtagat gcagaggatt
    38701 cctgaaatgg tatttagtag gaaggatata cctgtaagaa agatctgagg gagatgtgtt
    38761 tctacaaatg taatcacata agaaagagga atccattctg gagctgttaa agccagaata
    38821 ataacagcac ttagagccaa tacagcggtg ctaatcaatg accagataaa ggcaccgatt
    38881 agtttggctg tgatgatatg gtgttcagaa actggcaagg tcaaagtcag atagccttgt
    38941 cggtcgtaga cactaccttt gaagcgttta ataatcaaga aaatggttga aatcgcaagt
    39001 gtaagcatca agccaccaaa gactgtagct agaaaaagta gcatagtagc ctgactttct
    39061 tggtaaggta gatttttaaa gccttgtgtc tgtattccga tgagggcaga aaggactagc
    39121 acggctgcgt agagggctaa ataccacttg ttaacatttt taaattcgta gtgaactaaa
    39181 ttccaaaaca taaataatct cctttgctta ggccttaaat tcctgacgga agagttggtc
    39241 aatggattca cctgactcgt agcgaatatc atctacattt ccttgacgga cgacttttcc
    39301 gtcttttagg aagacaattt catccaagat tggctcgata tcagaaatca agtgggtaga
    39361 aatcaaaacg gtagaagttg gtgagtagtt gttgataatg gtattgagga tataagcacg
    39421 ggctgctgga tccaccccac caatgggttc atccaaaaca tagagacgag catcacggct
    39481 cataaccaaa atcagttgaa ccttttcttt gtttcctttt gatagtttct tgagacgact
    39541 attttcatca atgcccaggt ctgcaagtag atgatgagcg cgttcaagat tgaaatcttt
    39601 atagaaggtc ttgaagtagg ttagggcttc tttgaccttc atttgctcat tgagataggt
    39661 cgtatcaggc aaataagcta caacggcctt ggttgctggg cttgggtcca tgtcgttgat
    39721 gaggacacgt ccttgatctg gttgtaagag gccattaatt agtttaatca gggttgtttt
    39781 tcctgagccg tttggcccaa gaaggccgac aatttttcca gctggaatgt caagagaaac
    39841 attttcaagg gctggtgttg ctccatatga tttggataca ttttcaaata ctagtaatga
    39901 cataggctta aactccttta atataatcac tgactacgcc tggtagttct tctttttcat
    39961 agccaaaatg gatcatggag gaaacgaagt gttccaattc ttcttctgat aattgtttgc
    40021 gtgactgagc gattagctcc ttatccttag tcacaaatcg tccagttgtt cgcttgctgt
    40081 agacaaatcc ttctcgttca aggtctgata aggctctttg gatggtattg ggattgacac
    40141 cagcctcgct agctagctcc ctcacggttg gaagttgttg attgggttcc agtgtatggg
    40201 aaacaatctg aagcttgatt ttctccataa tctgtaaata gatgggtttt ttgttgtcaa
    40261 atgtccagga catcttagtc tcctttctct tatccttttg tcttaactaa ataatacaac
    40321 aaaacaaaaa acttgtcaag caaaaagaag aattgttttg ggaatcgctt aaaaaatggt
    40381 ataatgaaaa gaaaacgata aggagggaaa ggatgcgttg tccaaaatgt ggggctacca
    40441 agtcaagtgt tatcgatagt cgccaagcag aagaagggaa caccattcgt agaagacgtg
    40501 agtgcgacga atgccaacac cgttttacaa cctacgaacg agtagaagaa agaaccttag
    40561 tggttgttaa aaaagatggt acacgggaac aattctccag agataaaatc tttaatggga
    40621 ttatccgctc agcccagaaa cgtcctgtgt caagtgatga aatcaacatg gtagtcaatc
    40681 gtatcgaaca gaaactccgt ggtcgaaatg aaaatgaaat tcaaagtgag gacattggtt
    40741 cactcgtcat ggaggagttg gctgaattgg acgagattac ctatgtacgt tttgctagtg
    40801 tctatcgtag ttttaaggat gtcagtgagt tagagagctt gctccaacaa atcacccagt
    40861 cctctaaaaa gaaaaaggaa agataaatga agccaattga ccgtttttct tatctaaaga
    40921 ataatcgggt gtcgcaagat acctcatctc tggtacagtg ctacctcccg attatcggtc
    40981 aggaggcact gagcctttat ctttatacaa tcagtttttg ggataatggt agaaaggaat
    41041 atcttttttc aagtatcctc aatcatctca actttgggat ggatagactg ataaaatcat
    41101 tgaaaatctt atctgctttt aatctcttga ccctctatca aaagggggat gtttatcagc
    41161 tagccctcca tgctcctcta tctagtcaag acttcttgga gcatcctgtt tatcgcagac
    41221 tcttagagaa aaagattggc gactctgctg tggaggattt gaaagttgaa agtgctgatg
    41281 gtgaagaaat acctgtctca ctcaatcaag tctttccaga attggcagaa ctaggcagtc
    41341 aagaagacct tggtctcaag aagaaagtgg ccaatgattt tgacttggaa cattttcgcc
    41401 agctgatggc tcgagatgga cttcgttttg cggatgagca gtccgatgtc ttaaacctct
    41461 ttgctattgc cgaggagaag aaatggactt ggtttgaaac ctatcaattg gccaagtcaa
    41521 cagctgtttc tcaggttatt tcaaccaaac gcatgcgtga aaaaattgct caaaaaccag
    41581 tttcctctga ctttaatcct aaggaagcaa ccattatcaa ggaagctaaa agtaagactg
    41641 ccctgcagtt cttagcagaa atcaagcaaa cacgcaaggg gaccattacc caaacagaaa
    41701 gagaactttt gcaacagatg gctggcttgg gcttgctgga cgaagtcatc aatatcattc
    41761 tcttgttgac ctttaataag gtggattcgg caaacatcaa tgagaaatat gccatgaagg
    41821 tggctaatga ctatgcctat caaaagatac attcagcaga agaggccgtt ttacgaattc
    41881 gtgagcgagg gcagaaaaca aaaacacaaa aacagaatca gactgcccca gcaaaaacca
    41941 atattcctaa atggagtaac ccagattata agaatgaaac cagcgaggaa actcgtctgg
    42001 aactagaacg taagaaacaa gaactattag ctcgattaga aaaaggagga gattagatgg
    42061 aaagtgtcgg agacgtactc aaacgtcaac ccagccgttt ttattatcaa gatttggtcc
    42121 agaaaatcat gaaggaccct gatgttgcgg cttttatcca gcaagaatcc ttgactccag
    42181 aggaattaaa tcgcagtatc tccaagttta atcagtacat caccgagcgt gacaagtttc
    42241 tccgtgggga tacggattat attgccaaag gctacaagcc gattttggtt aagaatcatg
    42301 gctatgcaga tgtttcatat gaagaaactc ctgagctaat cgcggctgaa aaagaagcgg
    42361 ctattaagaa tcgtctcaag ctaatcaatc taccagccag tctcaaaaaa gctagtttgg
    42421 ctcaagttga tttggatgat ttgggacgct tgccagtttt tgaaaaacta ttagcctttg
    42481 tggagcaata tccagctatt cgaaaaggtc tttacttata tggagacttt ggtgtgggta
    42541 aaagtttcat ggtggcggcc ttagctcatg atttatcaga aaaacgtggt gtttcatcaa
    42601 ctctcctcca ctatcctagc tttgtcattg atgtcaaaaa tgctatcagt gatggcaatg
    42661 ttaagacctt ggtggatgag attaagctgt ctgaggtcct gattttagat gatattggcg
    42721 ccgagcaatc aaccgcttgg gtgcgtgacg aaatcctgca ggtcattctc caatatcgga
    42781 tgcaggaaaa tttaccgacc tttttcacat ccaacttcaa ctttgaagat ttggagaagc
    42841 attttgcgaa agtgaaacat ggaaatgacg aaacctggga agccagacgg gtcatggaac
    42901 gcatccgtta tttggctgag gagactcgtt tagaaggagt aaaccgtcga tgacagaaac
    42961 cattaaattg atgaaggctc atacttcagt gcgcaggttt aaagagcaag aaattcccca
    43021 agtagactta aatgagattt tgacagcagc caagatggca tcatcttgga agaatttcca
    43081 atcctactct gtgattgtgg tacgaagtca agagaagaaa gatgccttgt atgaattggt
    43141 acctcaagaa gccattcgcc agtctgctgt tttccttctc tttgtcggag atttgaaccg
    43201 agcagaaaag ggagcccgac ttcataccga caccttccaa ccccaaggtg tggaaggtct
    43261 cttgattagt tcggtcgatg cagctcttgc tggacaaaac gccttgttgg cagctgaaag
    43321 cttgggctat ggtggtgtga ttatcggttt ggttcgatac aagtctgaag aagtggcaga
    43381 gctctttaac ctacctgact acacctattc tgtctttggg atggcactgg gtgtgccaaa
    43441 tcaacatcat gatatgaaac cgagactgcc actagagaat gttgtctttg aggaagaata
    43501 ccaagaacag tcaactgagg caatccaagc ttatgaccgt gttcaggctg actatgctgg
    43561 ggcgcgtgcg accacaagct ggagtcagcg cctagcagaa cagtttggtc aagctgaacc
    43621 aagctcaact agaaaaaatc ttgaacagaa gaaattattg tagaaagtga gaaattatgg
    43681 ccctaccaac tattgccatt gtaggacgtc ccaatgttgg gaaatcaacc ctatttaatc
    43741 ggatcgctgg tgagcgaatc tccattgtag aagatgtcga aggagtgaca cgtgaccgta
    43801 tttatgcaac gggtgagtgg ctcaatcgtt cttttagcat gattgataca ggaggaattg
    43861 atgatgtcga tgctcctttc atggaacaaa tcaagcacca ggcagaaatt gccatggaag
    43921 aagcagatgt tatcgtcttt gtcgtgtccg gtaaggaagg aattaccgat gcagacgaat
    43981 acgtagcccg taagctttat aagacccaca aaccagttat cctcgcagtc aacaaggtgg
    44041 acaaccctga gatgagaaat gatatctatg atttctatgc tctcggtttg ggtgaaccat
    44101 tgcctatctc atctgtccat ggaatcggta caggggatgt gctagatgcg atcgtagaaa
    44161 atcttccaaa tgaatatgag gaagaaaatc cagatgtcat taagtttagc ttgattggtc
    44221 gtcctaacgt tggaaaatca agcttgatca atgctatctt gggagaagac cgtgttattg
    44281 ctagtcctgt tgctggaaca actcgtgatg ccattgatac ccactttaca gatacagatg
    44341 gtcaagagtt taccatgatt gatacggctg gtatgcgtaa gtctggtaag gtttatgaaa
    44401 atactgagaa atactctgtt atgcgtgcca tgcgtgctat tgaccgttca gatgtggtct
    44461 tgatggtcat caatgcggaa gaaggcattc gtgagtacga caagcgtatc gcaggatttg
    44521 cccatgaagc tggtaaaggg atgattatcg tggtcaacaa gtgggatacg cttgaaaaag
    44581 ataaccacac tatgaaaaac tgggaagaag atatccgtga gcagttccaa tacctgcctt
    44641 acgcaccgat tatctttgta tcagctttaa ccaagcaacg tctccacaaa cttcctgaga
    44701 tgattaagca aatcagcgaa agtcaaaata cacgtattcc atcagctgtc ttgaacgatg
    44761 tcatcatgga tgccattgcc atcaacccaa caccgacaga caaaggaaaa cgtctcaaga
    44821 ttttctatgc gacccaagtg gcaaccaaac caccaacctt tgtcatcttt gtcaatgaag
    44881 aagaactcat gcacttttct tacctgcgtt tcttggaaaa tcaaatccgc aaggcctttg
    44941 tttttgaggg aacaccgatt catctcatcg caagaaaacg caaataaaaa agtagaatct
    45001 ggaatgacag ttccggattt ttttgatata ataaaataat agaaaacgct atcaaaagaa
    45061 ggagggtgat gtcggtgatg gaacatttgt ttaaattctt acttttagca ccgtactttt
    45121 attttgataa ctggattgag aaggccaaca gaaatagtaa gttttttcca attttttatt
    45181 atttttactg gttttacatc cccttctatt ctctttttag ccttgcttgg acagttgttt
    45241 cagttctgtt tttcaatacc gtcttgagaa atgtgacaga tatcaagtta tggggcattt
    45301 ggtttctttt tattctgcta gctattggta tgaattggtt aacttattcc tgtttcaaag
    45361 aaatgtttcg cttgagacag gaactaggga agtctaaggg tggaaggcat tgatttatat
    45421 cggtttctat ttgtaggagg tggcttatgg tacctctaaa atcatttatt acacgctatt
    45481 ccaaggttta tattggtaat aacatttaat agaacgaaac taaagaaaac aatttaaaag
    45541 aggaggtttg tgatggaata cttgtttaaa atgataatct tattaccctg tttttacttt
    45601 ttcagctgga ttgaaaaggc aaacagagat agtaagattt tcccaatttt ttactatttt
    45661 tactggattt acatcaccct ctatgctctt tttagccttg cttggacagt tttttcagtt
    45721 ctgtttttca atatcgtctt gagaaatttg acagatatca agttatgggg tatttggcta
    45781 ttattactac ttatcgcttt tgctagtgac tggttagact atatctgttt caaaaaaatg
    45841 cttgacttga gacgggaact agggaagtct aaaggcggaa ggcattgatt tatactcttc
    45901 gaaaatctct tcaaaccacg tcaacgtcgc cttggattat atatgtaact gacttcgtca
    45961 gtcttatcta caacctcaaa gcagtgcttt gagcaacttg cggctagttt cctagtttgc
    46021 tctttgattt tcattgagta ttatattact ttctatttgt aggaggtggc ttatgaagat
    46081 tcctctctta actttggcaa ggcataaatt tgtttatgtc ttgcttactt tgctttttct
    46141 tgctttggtt tatcgtgatg ttttgatgac ttatttcttt tttgatattc atgcgcccga
    46201 tctagctaaa ttcgatggac aagcaattaa aaatgactta ttaaaatcag cattagattt
    46261 tcgtattctc cagttcaatc taggttttta tcaatcattt attattccaa tcatcattgt
    46321 tttgctaggt tttcaatata ttgagctgaa aaataaagtt ttacgattga gtattggaag
    46381 agaagtgagc tatcaagggt taaaaagaaa gttgactttg caagttgcaa gtatcccttg
    46441 tttgatatat ttagtgactg tgctgataat tgcaattata acctatttct ttgggacttt
    46501 ttctcctctt gaatggaatt ctctattttc tgatgggagt ggtttacaaa gactcctaga
    46561 tggagagata aaaagctatt tgttctttac ttgtgtccta ctaatcggta ttttcatcaa
    46621 tgcaatctat tttttacaaa tagttgatta tgtggggaat gtgactcgtt cggcaatcac
    46681 ctatttgatg tttctttggc ttggttctat gctgctctat agtgccttgc cttactatat
    46741 ggttcctatg acgagtttga tgcaagctag ctatggggat gtaagtttga tgaaactctt
    46801 tactccttat atccttcatg ttgtccctta tatggtactt aaaaaatatg aagataatgt
    46861 ttaagaattt taacaatatt tggctaaaga gaaagatcgt tttactactt cgtatagttc
    46921 tgatgatgat tttgataaac tatctattgt caacagcggt tcaaaagcag gatgctgtta
    46981 tctttttcaa gagagaattg atttcaattt tttcctataa tgactattct gaagcgaatt
    47041 tagaaatccc caaactcttg ttaaaccttt cgcttttcat ggtaggatgg ctctctgtca
    47101 ttttacttga aagtgatttg gcagaccatt accatcactt gattcgctat caatcaagct
    47161 cctttttcga ttatacaagg aaacgattgg ttgtcatttc taaatttttt actcaagatt
    47221 tgtttgtctg gtttcttggt ttacttccgc taggaattca tttcaaaaca gtcgcacttt
    47281 tctttttact tgctcagtta atgatgttgt acttactact gtcttatctg atagcactga
    47341 ttagtgcggg cgctggtttt tctttttttc tctatttttt ggcatttgtg ggacaagaat
    47401 ggatgatgga tcatattgta acagtgtatt tagtactctt aagcttatta gttatgttga
    47461 ttgttagtcg cttggaagag aaatttaaga aaggataaac gatgagactt gaaattataa
    47521 atggacagaa aatttatggg aaaagaccta ttttaaatca gttgaatttg gtgtttcaat
    47581 caggaaaaat ttatggactt aaaggtgata atggatctgg caagacggtt cttttaaaga
    47641 tacttgctgg ttatattaag cttgacaaag gaaaagttct tcaagatggt aaagtttacg
    47701 gggtaaaaaa tcattatatt caggatgcag gaattttaat tgaaaaagtc gagtttttat
    47761 ctcatttatc cctgagagaa aatttggaac tgttaaggta tttttcatct aaagttacgg
    47821 aaaaaagaat tgcctattgg attcaatact atgatttaca ggaatttgaa gacgttgaat
    47881 accgtcattt atccttggga acaaagcaaa aaatggcctt gattcaagcc tttatttcct
    47941 ctccttctat actctttctc gatgaaccta tgaatgcttt ggatgagaag agtgtgaggt
    48001 taaccaaaca ggtcatttta tcttacctga aaaaagaaaa tggtctggtt atcctgacgt
    48061 cgcacatatc ggaagatatt tcagaccttt gtacagatgt attagttgtc gaaaatggac
    48121 atatacaata tgtaaaggat atacaatcct aggagatggc ttatggcaca tctaaaatca
    48181 tttattacac gctattccaa ggtttatatt ggtttagttc tgctgatctg gctgtctttc
    48241 ttctttatcc cttgggatag agcgattctg ggggtaagga ttgacatctt catcatgcag
    48301 aaaatcttgc tagcttttgg aattctgtcc attctcatgg ccttgctgtc caagaaagtc
    48361 agtctctttg tttttggact gatttgctgt ctttctcttt ggattaactt atttatcaca
    48421 tttgccattt tgccgatttt tggcaattaa acagtcataa aagtcggaga ggttagcttg
    48481 aaaactaacc tctttttcct tttcaaaatg gggattcttc cttgaaaata atcagtaatt
    48541 gtgctaaaat taaaggaaca ttctaaaata ttcggaattt aaagtaagga aaaacatggc
    48601 taatatttta aaaacaatta tcgaaaatga taaaggagaa atccgtcgtc tggaaaagat
    48661 ggctgacaag gttttcaaat acgaagacca aatggctact ttgactgacg accaactaaa
    48721 agcaaaaaca gttgaattta aggaacgtta tcaaaatgga gaatcactgg attcattgct
    48781 ttacgaagca tttgcggttg tccgtgaagg tgccaaacgt gtcctaggtc tcttccctta
    48841 taaggttcag gtcatggggg ggattgttct tcaccatggt gacgtgccag agatgcgtac
    48901 aggggaaggg aaaaccttga ctgcgaccat gccggtatac ctcaatgccc tttcaggtaa
    48961 aggggttcac gtagttacgg ttaatgaata cctgtcagaa cgtgacgcga ctgagatggg
    49021 tgaattgtac tcttggcttg gtttgtcagt agggattaac ttggctacca aatctccaat
    49081 ggagaaaaaa gaagcctatg agtgtgatat tacttactca actaactcag aaatcggatt
    49141 tgactacctt cgtgacaaca tggtcgttcg cgccgaaaac atggtacaac gtccgcttaa
    49201 ctatgccttg gtcgatgagg ttgactctat cttgattgac gaggctcgta cacctttgat
    49261 tgtatcaggt gccaatgcgg ttgaaaccag tcagttgtat cacatggcag accactatgt
    49321 aaaatctttg aacaaagatg actacatcat cgatgtgcag tctaagacta ttggtttgtc
    49381 tgattcaggg attgacaggg ctgaaagcta cttcaaactt gaaaacctct atgacatcga
    49441 aaacgtggct ttgactcact ttatcgataa cgcccttcgt gccaactaca tcatgcttct
    49501 cgatattgac tatgtggtga gcgaagagca agaaatcttg attgtcgacc aatttacagg
    49561 tcgtaccatg gaaggtcgtc gttattctga tggattgcac caagctattg aagccaaaga
    49621 aggtgtgcca atccaggatg aaaccaagac atctgcctca atcacgtacc aaaacctttt
    49681 ccgtatgtac aagaaattgt ctggtatgac gggtacaggt aagactgagg aagaagaatt
    49741 ccgtgaaatc tacaacattc gtgttattcc aatcccaaca aaccgtcctg ttcaacgtat
    49801 tgaccactca gaccttcttt atgcaagtat cgaatctaag tttaaagcgg ttgtcgaaga
    49861 cgttaaggct cgttaccaaa agggtcaacc tgtcttggtt ggtacagtgg cggttgaaac
    49921 tagtgactac atttctaaga aattggttgc agctggtgtt cctcacgaag tcttgaatgc
    49981 caaaaaccac tatagagaag cccaaatcat catgaatgct ggtcaacgtg gtgccgttac
    50041 catcgcaacc aacatggcgg gtcgtggtac cgacatcaag cttggtgaag gtgttcgtga
    50101 acttggagga ctttgtgtta ttggtacaga acgtcatgaa agtcgtcgta tcgataacca
    50161 gcttcgtgga cgttcaggtc gtcaaggaga tccaggtgag tcacaattct acctatctct
    50221 tgaagatgat ttgatgaaac gttttggttc tgaacgcttg aagggaatct ttgaacgttt
    50281 gaacatgtct gaagaggcga ttgagtctcg catgttgacg cgtcaggttg aagcagctca
    50341 gaaacgtgtc gaaggaaata actacgatac ccgtaaacaa gtccttcaat acgatgatgt
    50401 catgcgtgaa caacgtgaga ttatctatgc tcaacgttac gatgtcatca ctgcagatcg
    50461 tgacttggca cctgaaattc aggctatgat caaacgcacg attgaacgtg tcgttgatgg
    50521 tcatgcgcgt gccaaacaag atgaaaaact agaggcaatt ttgaactttg ctaagtacaa
    50581 cttgcttcct gaagattcta ttacgatgga agacttgtca ggcttgtctg ataaggccat
    50641 caaggaagag cttttccaac gtgccttgaa ggtttacgat agtcaggttt caaaactacg
    50701 cgatgaagaa gcagttaaag aattccaaaa agttttgatt ctacgagtgg tggataacaa
    50761 gtggacagat catatcgatg cccttgatca attgcgtaac gcggttggac ttcgtggcta
    50821 tgctcagaac aaccctgttg ttgagtatca ggcagaaggt ttccgtatgt ttaatgatat
    50881 gattggttcg attgagtttg atgtgacacg cttgatgatg aaagcacaaa ttcatgaaca
    50941 agaaagacca caggcagaac gtcatatcag tacaacagcg actcgcaata tcgctgctca
    51001 ccaagcaagt atgccagaag atttggattt gagccagatt ggacgcaatg aactttgccc
    51061 atgtggttct ggtaagaaat ttaaaaactg tcacggtaaa agacaataaa atgagatagt
    51121 ttagaggcgg atatcttgtg aaaagtaaat ttttactggg tatccgtttg ctttataagg
    51181 agatgagtta tggtatttac agcaaaaagc tctaaaataa atatagaaga agttcgtgcc
    51241 ttgtcaaaat tagaaggtca ggctttggag aggaaatcac agcgcgatca agagctagaa
    51301 gccattatac gtggagaaga tcagcgaatt ctcttggtaa tcgggccatg ctcatctgac
    51361 aacgaagaag ctgtccttga atacgctaag cgtttggcag tcctacaaga agaagtggca
    51421 gatcgtatct ttatggttat gcgtgtttat actgccaaac cccgtaccaa cggagatggc
    51481 tataagggct tgattcacca gcctaacgcg acagaagcgc ctagtcttat caatggaatc
    51541 aaagccgttc gccatcttca ctatcgtgtc atcacagaaa cagggatgac aactgctgat
    51601 gaaatgcttt atcctgaaaa ccttccgctt gtagatgatt tgatttctta catggcagtt
    51661 ggtgcccgtt cagttgaaga ccagcaacac cgctttgtgg caagtggggc aggattttct
    51721 actggtttta aaaatccaac ctctggaaat ctcaatgtca tgtttaatgg gatttatgct
    51781 gctcaaaaca aacaaagttt ccttttctta ggaaaagaag tagaaacaac tgggaacccg
    51841 ctttcacacg ctattcttcg tggtgctctt aatgagtatg gaaaaaatat tcccaactac
    51901 tattatgaca atttaattga taccattgcc caatatgaga aaatgggctt ggaaaatcct
    51961 tttatcatca ttgataccaa tcatgacaat tctggtaagc agtatattga acagatccga
    52021 attgtccgcc agaccttgat taaccgtgct tggaatgaaa aaattaagca gttcgttcgt
    52081 ggttttatga ttgagtctta tctggaagat ggtcgacaaa atgagccaga agtatttggc
    52141 aagtctatca cagacccttg cctgggttgg gataacacag aagctcttgt cagagaaatt
    52201 tacaaaacgt taggagaata agatggcatt tattgaaaaa ggtcaagaaa tcgatatgga
    52261 agtcatcaag gctgaaaccc aattgtctgc ggaagccttg agactcaagg aaagccgtga
    52321 cagggaattg gcagatatta tttcagggga agatgaccgt attctcttgg tgattggtcc
    52381 ttgctcttct gataatgaag aggcggtctt ggaatatgct cgccgtttat ccgccttgca
    52441 aaagaaggta gcggacaaga ttttcatggt catgcgcgtg tatactgcta agcctcgtac
    52501 caatggagac ggctataaag gattggttca ccagccagat acttctaagg ctccaagcct
    52561 gattaacggt ttgcaggctg tgcgccagtt gcattaccgc gtgattacag agactggttt
    52621 gacaacggca gatgagatgc tttatccgtc aaatctgatc ttggtggatg acttggtcag
    52681 ctaccatgcc gttggagctc gttctgtgga agaccaagag caccgctttg tggcttctgg
    52741 gattgatgca ccagtaggga tgaaaaatcc aacctcagga aatttgggtg ttatgtttaa
    52801 cgccatctat gctgctcaaa acaagcaaac cttcctttat catgggcagg aagttgagac
    52861 atcaggtaat cctttggccc atgttatcct ccgtggagca gtcaacgagt atggcaatta
    52921 tatgccgaat tactactatg aaaacctact ccaagccatt gaacgctatg aaaccatggg
    52981 acttgaaaat ccttttatcc tcattgacac caaccatgat aactcaggca agcaatatat
    53041 ggagcagatt cgaattgttc gccagacctt gcagaatcgt gattggaatg agaaaattaa
    53101 aaagacggtt cgaggattta tgattgaatc ttacctagca gatggtcgtc aaaaccaacc
    53161 agagatcttt ggttgctcta ttactgaccc ttgcctaggt tgggaaaata cagaggcctt
    53221 ggtagaagag atttatgtta ccttgacaaa ataagtgaaa aggatggagt tggggaatct
    53281 caactccttt tgatgagaat gatagttgga cacggaattg acatcgaaga attggcttcg
    53341 atagaaagcg cagttacacg acatgaagga tttgctaagc gtgtactgac cgctcaggaa
    53401 atggagcgct tcaccagtct caaaggacgc aggcaaatag aatatttagc tggtcgctgg
    53461 tcggctaagg aggccttttc caaggctatg ggaacgggca ttagcaagct cggttttcag
    53521 gatttggaag tattgaacaa tgaacgtggg gcgccttatt ttagtcaggc accattttca
    53581 ggaaagattt ggctgtctat cagccacacc gatcagtttg tgacagccag tgtcattttg
    53641 gaggaaaatc atgaaagcta gtccacatag accaaccaag gctctgattc atctgggagc
    53701 tattcgacaa aatattcagc aaatgggggc tcatatccct caaggaacgc tcaagttggc
    53761 tgtggttaag gccaatgctt atggtcatgg agctgttgcc gttgccaagg caattcaaga
    53821 tgatgttgat ggcttttgcg tttccaatat cgatgaagcc attgaactca gacaagctgg
    53881 actcagcaag ccaatcctca ttttaggagt ttctgaaatc gaagctgttg ctctagctaa
    53941 agaatatgac ttcaccttga cagtggctgg actggagtgg attcaagcac tcttagataa
    54001 ggaagtggac ctaactggat tgacagtcca cctcaagatt gattcaggga tgggacggat
    54061 tggttttaga gaggcaagtg aggttgagca ggctcaagat ttgctccaac aacacggtgt
    54121 tcgtgttgaa ggaatcttta cccactttgc tactgctgat gaggaatcag atgactattt
    54181 taatgcccag ttagaacggt ttaaaactat tttagctagt atgaaggaag ttccagagct
    54241 ggttcatgct agcaattctg caacgactct ttggcatgta gagactattt tcaatgcggt
    54301 tcgtatggga gatgccatgt atggtctcaa tccaagtgga gcggtcttgg ctttgcctta
    54361 tgatttgata ccggccttga ccttggagtc tgctctggtt catatcaaga cagttccagc
    54421 tggtgcttgc atgggctatg gagcaactta tcaaacggat agcgagcaag tcatcgcgac
    54481 cgtgccaatc gggtatgcag atggatggac aagagacatg caaaatttct ctgtcttggt
    54541 agatggccaa gcttgcccaa ttgtcggcag ggtttcgatg gaccaaatca ctattcgatt
    54601 gcctaagcct tacccactcg gaaccaaggt aaccttgatt ggctccaatg gggataagga
    54661 aatcactgca actcaggtag cgacctaccg cgtaaccatt aactatgagg tggtttgcct
    54721 cctcagcgac cgtattccga gagaatatta ttagaaaaga aaggagtgga gcatgaatct
    54781 acatcaaccc ttgcatgtct tgcctggtgt gggaccaaag tcagcagaaa aatacgccaa
    54841 actaggaatt gaaaacttgc aagatctctt gctctacttt cctttccgtt atgaagactt
    54901 caaaaccaag caggtgctgg aactagaaga cggtgagaag gcagttcttt ctggtcaggt
    54961 agtgactcct gctagtgtcc agtattatgg tttcaagcgc aatcgcctgc gttttagtct
    55021 caagcaggga gaggtcgttt ttgcggtgaa tttctttaac cagccctatc tggctgataa
    55081 aatagagttg ggagcaaccc ttgctgtctt tggaaaatgg gaccgcgcta aggctagtct
    55141 gactgggatg aaggttctgg ctcaggtaga agatgacctc cagcctgtct atcgtctggc
    55201 tcagggaatc agtcaggcca gtctggtcaa ggtcatcaag acggcttttg atcagggact
    55261 ggacctcttg atagaagaaa atctgcccca gtctttacta gacaaataca aactcatgtc
    55321 ccgttgtcag gcagtccgag ctatgcattt tccaaaggat ttggcagaat acaagcaggc
    55381 tcttcgccgt atcaagtttg aggaactctt ttatttccaa atgcagttgc agatgctcaa
    55441 gtctgaaaat agagttcagg gaagtggtct ggttctgaat tggtctcagg aaaaagtgac
    55501 agcagttaaa gcaagtcttc cttttgccct gacccaagct caggaaaaga gtttgcagga
    55561 aattttaact gatatgaagt ccgaccacta catgaatcgt ctcctacaag gagatgtggg
    55621 gagcggaaaa acggtagtcg ctggcttggc catgtttgcg gcagtgacag caggttatca
    55681 ggctgcccta atggtaccaa cagaaatcct cgcagagcaa cactttgaga gtttacagaa
    55741 cctttttccc aatttgaaac tggctctctt gacaggttcc ttgaaagctg cagaaaagag
    55801 agaggtcttg gagaccattg ccaagggtga ggctgatttg attataggaa ctcacgctct
    55861 gatacaagat ggggtggagt atgctcgtct tggtttgatt attatcgatg agcagcaccg
    55921 ttttggtgtg gggcaaaggc gtattttacg ggaaaaaggc gacaatccag atgtcctcat
    55981 gatgacggcg actcccattc cacggacgct tgccatcaca gcctttggag atatggatgt
    56041 ttccattatc gaccagatgc cagcaggtcg gaagcctatt gtgacgcgct ggatcaaaca
    56101 tgagcaacta cctcaggtct tgacttggtt agagggggaa attcaaaaag gttcccaagc
    56161 ctatgtcatc tctcctttga ttgaagaatc agaagctcta gatttgaaaa atgccattgc
    56221 cttatcagag gagttgacga ctcattttgc aggcaaggca gaggtggctc ttctacatgg
    56281 taggatgaag agtgacgaaa aagaccagat catgcaggat ttcaaggaga gaaagacgga
    56341 tattctggtt tcgacgacgg ttattgaggt tggggtcaat gttcccaatg cgactgtcat
    56401 gattatcatg gatgccgatc gcttcggtct cagtcaactt caccagctta gaggtcgtgt
    56461 cggtcggggg gacaagcagt cctacgctgt tctcgttgcc aatcccaaga cggattctgg
    56521 gaaagaccgc atgcgcatca tgacagaaac gaccaatgga tttgtccttg cggaggaaga
    56581 tttgaaaatg cgtggttctg gtgagatttt tggaaccaga cagtcaggac ttccagagtt
    56641 ccaagtggct gatattatcg aagattttcc gattttagaa gaagcaagaa aggttgctag
    56701 ctacattagt tctatagaaa cttggcaaga agatccagag tggcgcatga ttgcccttca
    56761 tctggaaaag aaagaacatc tggattaagc tttctctaag gaaaacttaa gctagttttt
    56821 agatttggct cttatactaa agtcatcaaa aagaaacgag gactctcata tgacagtaac
    56881 gattaaagta aattaccaaa ccactttcca aaagaaggaa gca
//
LOCUS       DAVKMJ010000007        55213 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000007 DAVKMJ010000000
VERSION     DAVKMJ010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 55213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55213
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.007"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            54..169
                     /gene="rrf"
                     /locus_tag="VW348_000424"
     rRNA            54..169
                     /gene="rrf"
                     /locus_tag="VW348_000424"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            174..246
                     /locus_tag="VW348_000425"
     tRNA            174..246
                     /locus_tag="VW348_000425"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:207..209,aa:Val,seq:tac)
     gene            252..322
                     /locus_tag="VW348_000426"
     tRNA            252..322
                     /locus_tag="VW348_000426"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:284..286,aa:Gly,seq:tcc)
     gene            357..430
                     /locus_tag="VW348_000427"
     tRNA            357..430
                     /locus_tag="VW348_000427"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:391..393,aa:Ile,seq:gat)
     gene            513..602
                     /locus_tag="VW348_000428"
     tRNA            513..602
                     /locus_tag="VW348_000428"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:549..551,aa:Ser,seq:tga)
     gene            613..686
                     /locus_tag="VW348_000429"
     tRNA            613..686
                     /locus_tag="VW348_000429"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:647..649,aa:Met,seq:cat)
     gene            690..762
                     /locus_tag="VW348_000430"
     tRNA            690..762
                     /locus_tag="VW348_000430"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:723..725,aa:Phe,seq:gaa)
     gene            775..855
                     /locus_tag="VW348_000431"
     tRNA            775..855
                     /locus_tag="VW348_000431"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:809..811,aa:Tyr,seq:gta)
     gene            860..930
                     /locus_tag="VW348_000432"
     tRNA            860..930
                     /locus_tag="VW348_000432"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:892..894,aa:Trp,seq:cca)
     gene            945..1017
                     /locus_tag="VW348_000433"
     tRNA            945..1017
                     /locus_tag="VW348_000433"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:978..980,aa:His,seq:gtg)
     gene            1028..1099
                     /locus_tag="VW348_000434"
     tRNA            1028..1099
                     /locus_tag="VW348_000434"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1060..1062,aa:Gln,seq:ttg)
     gene            1109..1192
                     /locus_tag="VW348_000435"
     tRNA            1109..1192
                     /locus_tag="VW348_000435"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1143..1145,aa:Leu,seq:caa)
     gene            1299..2576
                     /locus_tag="VW348_000436"
     CDS             1299..2576
                     /locus_tag="VW348_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEU9745393.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2652..4136
                     /locus_tag="VW348_000437"
     CDS             2652..4136
                     /locus_tag="VW348_000437"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEU9745394.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIALLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNMQGQYKLTDFDAEILELFAAEYATEEETAAEIKRVYELDS
                     YIEDPHTAVASAVYRKYQAVTDDATKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLETAPVRHKTTVAAADMQAAVEAYLGL"
     gene            4197..5477
                     /locus_tag="VW348_000438"
     CDS             4197..5477
                     /locus_tag="VW348_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU9745395.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5481..6101
                     /locus_tag="VW348_000439"
     CDS             5481..6101
                     /locus_tag="VW348_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU9745396.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6267..7409
                     /locus_tag="VW348_000440"
     CDS             6267..7409
                     /locus_tag="VW348_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU9745397.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSAVAEEAPQETTPGEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPESSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            7815..8153
                     /locus_tag="VW348_000441"
     CDS             7815..8153
                     /locus_tag="VW348_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEU9745398.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRHFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            8164..8522
                     /locus_tag="VW348_000442"
                     /pseudo
     CDS             8164..8522
                     /locus_tag="VW348_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
     gene            8629..9246
                     /gene="pcp"
                     /locus_tag="VW348_000443"
                     /pseudo
     CDS             8629..9246
                     /gene="pcp"
                     /locus_tag="VW348_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(9274..10131)
                     /locus_tag="VW348_000444"
     CDS             complement(9274..10131)
                     /locus_tag="VW348_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEU9745399.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQAYLFPLLVFFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQRFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10261..11403
                     /gene="tgt"
                     /locus_tag="VW348_000445"
     CDS             10261..11403
                     /gene="tgt"
                     /locus_tag="VW348_000445"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEU9745400.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            11501..13318
                     /locus_tag="VW348_000446"
     CDS             11501..13318
                     /locus_tag="VW348_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEU9745401.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMVFLLSAAAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTV
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13471..14622
                     /gene="nagA"
                     /locus_tag="VW348_000447"
     CDS             13471..14622
                     /gene="nagA"
                     /locus_tag="VW348_000447"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEU9745402.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14785..15843
                     /locus_tag="VW348_000448"
     CDS             14785..15843
                     /locus_tag="VW348_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEU9745403.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15994..16359
                     /locus_tag="VW348_000449"
     CDS             15994..16359
                     /locus_tag="VW348_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEU9745404.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16435..17376
                     /locus_tag="VW348_000450"
     CDS             16435..17376
                     /locus_tag="VW348_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEU9745405.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAS
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17324..18340
                     /locus_tag="VW348_000451"
     CDS             17324..18340
                     /locus_tag="VW348_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEU9745406.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVTQMRVGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18342..18668
                     /gene="comGC"
                     /locus_tag="VW348_000452"
     CDS             18342..18668
                     /gene="comGC"
                     /locus_tag="VW348_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEU9745407.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKDDGRITEEQVKAYKEYNDKNGGA
                     NRKVND"
     gene            18637..19065
                     /locus_tag="VW348_000453"
     CDS             18637..19065
                     /locus_tag="VW348_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEU9745408.1"
                     /translation="MEEQIVKSMIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVE
                     EQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQKLPVPKGIQAPSGQSIIF
                     DRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            19070..19330
                     /locus_tag="VW348_000454"
     CDS             19070..19330
                     /locus_tag="VW348_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745409.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQININGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19293..19754
                     /locus_tag="VW348_000455"
     CDS             19293..19754
                     /locus_tag="VW348_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU9745410.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALLVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVRFRFQFQKGLEREFIYRVEKEKS"
     gene            19732..20145
                     /locus_tag="VW348_000456"
     CDS             19732..20145
                     /locus_tag="VW348_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEU9745411.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            20282..20869
                     /locus_tag="VW348_000457"
     CDS             20282..20869
                     /locus_tag="VW348_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9745412.1"
                     /translation="MKHDFNHKAETFDSPKNIFLANLVCQAVEKQIDILSDKEILDFG
                     GGTGLLALPLAKQAKSVTLVDISEKMLEQAHLKAEQQAIKNIQFLEQDLPKNPLEKEF
                     DCLAVSRVLHHMPDLDAALSLFHQHLKEDGKLIIADFTKTEANHHGFDLAELENKLIE
                     HGFSSVHSQILYSAEDLFQGNHSEFFLIVAQKSLA"
     gene            20930..21883
                     /locus_tag="VW348_000458"
     CDS             20930..21883
                     /locus_tag="VW348_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9745413.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGF
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVELFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21934..23124
                     /locus_tag="VW348_000459"
     CDS             21934..23124
                     /locus_tag="VW348_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEU9745414.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGTDAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23273..23644
                     /gene="rnpA"
                     /locus_tag="VW348_000460"
     CDS             23273..23644
                     /gene="rnpA"
                     /locus_tag="VW348_000460"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEU9745415.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23619..24443
                     /locus_tag="VW348_000461"
     CDS             23619..24443
                     /locus_tag="VW348_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU9745416.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24462..25448
                     /locus_tag="VW348_000462"
     CDS             24462..25448
                     /locus_tag="VW348_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEU9745417.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QAESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25499..26122
                     /locus_tag="VW348_000463"
     CDS             25499..26122
                     /locus_tag="VW348_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEU9745418.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLEKQAKILDIPTVKGIYYLAYSDGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26253..27710
                     /locus_tag="VW348_000464"
     CDS             26253..27710
                     /locus_tag="VW348_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEU9745419.1"
                     /translation="MEVISSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFIFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27733..28014
                     /locus_tag="VW348_000465"
     CDS             27733..28014
                     /locus_tag="VW348_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9745420.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            28091..28576
                     /locus_tag="VW348_000466"
     CDS             28091..28576
                     /locus_tag="VW348_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9745421.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28593..29258
                     /locus_tag="VW348_000467"
     CDS             28593..29258
                     /locus_tag="VW348_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEU9745422.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAVDPAGAARAFKDEIKR
                     IWG"
     gene            29262..30125
                     /locus_tag="VW348_000468"
     CDS             29262..30125
                     /locus_tag="VW348_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEU9745423.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            30127..30831
                     /locus_tag="VW348_000469"
     CDS             30127..30831
                     /locus_tag="VW348_000469"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEU9745424.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIIVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            31010..32683
                     /locus_tag="VW348_000470"
     CDS             31010..32683
                     /locus_tag="VW348_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU9745425.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32795..33886
                     /gene="ulaG"
                     /locus_tag="VW348_000471"
     CDS             32795..33886
                     /gene="ulaG"
                     /locus_tag="VW348_000471"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEU9745426.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            34000..35976
                     /gene="tkt"
                     /locus_tag="VW348_000472"
     CDS             34000..35976
                     /gene="tkt"
                     /locus_tag="VW348_000472"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEU9745427.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            36093..36392
                     /gene="yajC"
                     /locus_tag="VW348_000473"
     CDS             36093..36392
                     /gene="yajC"
                     /locus_tag="VW348_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU9745428.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36439..36867
                     /locus_tag="VW348_000474"
     CDS             36439..36867
                     /locus_tag="VW348_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEU9745429.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQQYEILYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36869..37279
                     /locus_tag="VW348_000475"
     CDS             36869..37279
                     /locus_tag="VW348_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745430.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37580..40231
                     /gene="adhE"
                     /locus_tag="VW348_000476"
                     /gene_synonym="adhC"
     CDS             37580..40231
                     /gene="adhE"
                     /locus_tag="VW348_000476"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEU9745431.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(41139..41447)
                     /locus_tag="VW348_000477"
     CDS             complement(41139..41447)
                     /locus_tag="VW348_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9745432.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEVHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(41444..41752)
                     /locus_tag="VW348_000478"
     CDS             complement(41444..41752)
                     /locus_tag="VW348_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9745433.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(41757..43052)
                     /locus_tag="VW348_000479"
     CDS             complement(41757..43052)
                     /locus_tag="VW348_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9745434.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(43070..44479)
                     /locus_tag="VW348_000480"
     CDS             complement(43070..44479)
                     /locus_tag="VW348_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU9745435.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLELDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWLERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            44637..45365
                     /locus_tag="VW348_000481"
     CDS             44637..45365
                     /locus_tag="VW348_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9745436.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            45824..46018
                     /locus_tag="VW348_000482"
     CDS             45824..46018
                     /locus_tag="VW348_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU9745437.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(46384..47694)
                     /locus_tag="VW348_000483"
     CDS             complement(46384..47694)
                     /locus_tag="VW348_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEU9745438.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALKLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            47931..48803
                     /locus_tag="VW348_000484"
     CDS             47931..48803
                     /locus_tag="VW348_000484"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEU9745439.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
     gene            48934..49765
                     /locus_tag="VW348_000485"
                     /pseudo
     CDS             48934..49765
                     /locus_tag="VW348_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            49876..50802
                     /locus_tag="VW348_000486"
     CDS             49876..50802
                     /locus_tag="VW348_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU9745440.1"
                     /translation="MDLSQTMPSYAQVVSLYDDTSISVSNNETDKVLAGSLYTDTNEQ
                     GLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQFQTKIVRVINDE
                     DDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTEELQKNKKYTVLS
                     QQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRSKEIGVMKAVGYQ
                     NRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSITKVFELNLLSVLG
                     TLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            50979..51986
                     /gene="gap"
                     /locus_tag="VW348_000487"
     CDS             50979..51986
                     /gene="gap"
                     /locus_tag="VW348_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEU9745441.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(52053..52889)
                     /locus_tag="VW348_000488"
     CDS             complement(52053..52889)
                     /locus_tag="VW348_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU9745442.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWKEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            53015..55210
                     /locus_tag="VW348_000489"
     CDS             53015..55210
                     /locus_tag="VW348_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEU9745443.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
BASE COUNT        16851 a         9850 c        12081 g        16431 t
ORIGIN      
        1 acggttttct tgaattgaat agatattcaa ttttgagtag gtattactca gagttaagtg
       61 acgatagcct aggagataca cctgtaccca tgccgaacac agaagttaag ccctagaacg
      121 ccggaagtag ttgggggttg ccccctgtga gatagggaag tcgcttagct ctagggagtt
      181 tagctcagct gggagagcat ctgccttaca agcagagggt cagcggttcg attccgttaa
      241 ctcccatttt agcgggtgta gtttagtggt aaaactacag ccttccaagc tgttgtcgcg
      301 agttcgattc tcgtcacccg ctttgaactt tgttctttgt accaagtttt tgacttgggc
      361 gcgtagctca ggtggttaga gcgcacgcct gataagcgtg aggtcggtgg ttcgagtcca
      421 ctcgtgccca tagtgtttag tccattacta ggggattgga atattatctg ttcactaaga
      481 ggacacgggc ttgttcccgt ataaactatt ttggaggatt acccaagtcc ggctgaaggg
      541 aacggtcttg aaaaccgtca ggcgtgtaaa agcgtgcgtg ggttcgaatc ccacatcctc
      601 cttttatatt aacgcgggat ggagcagctc ggtagctcgt cgggctcata acccgaaggt
      661 cgtaggttca aatcctgctc ccgcaataag gctcggtagc tcagttggta gagcaatgga
      721 ttgaagctcc atgtgtcggc ggttcgattc cgtctcgcgc catttatata ttttggaagg
      781 gtagcgaaga ggctaaacgc ggcggactgt aaatccgctc cttcgggttc gggggttcga
      841 atccctcccc ttccatttta cgggcatagt ttaaaggtag aactaaggtc tccaaaacct
      901 tcagtgtggg ttcaattcct actgcccgtg ttaatagaat tatggcgggt gtggtgaagt
      961 ggttaacaca ccagattgtg gctctggcat gcgtgggttc gatccccatc actcgcctat
     1021 tttatattgg ggtatagcca agcggtaagg caagggactt tgactccctc atgcgttggt
     1081 tcgaatccag ctaccccagt tactatttgc cggcgtggcg gaattggcag acgcgctgga
     1141 ctcaaaatcc agtgtccgca aggacgtgcc ggttcgaccc cggccgccgg tatagtatag
     1201 tgttaggaac gttgttattc ttcgttcctt ttttatatta tttttggtat aattatagtt
     1261 attcaaattt tgtttagatt gagaaagtgt agggtagtat gtcttgttct atcgatttat
     1321 taaaacatcg gtatttgaaa aatattaaag aaaatcctga attgtttgtc ggaattgagt
     1381 tggagtatcc tgttgcaagt ttagaagggg atgctacaga tgttgaagtt ataaaggatc
     1441 tatttcatta tttagtttct actttggatc tcaccgtagc aaaggtagat gattttggca
     1501 atctgatcca gttagtagat ccgataagtc aggatgctat tttatttgaa gtttcctata
     1561 caacgattga gtttgcattt ggtaaggctg aaacgattca agaggtcgaa aatcgtttca
     1621 ataattatat gaatgtaatt cagagaaagt tagctgaatc aaatcatgct attgttggct
     1681 gtggtatcca tcccaactgg gataaaaatg agaattgtcc agtggcttat ccacgctatc
     1741 agatgttgat ggattatttg aatttgagta gaaatattat taaatcagat ttacatcatt
     1801 tccctgaata tggtactttt atctgtggga gccaggttca gctggatatt tcaaaaacca
     1861 actacttacg ggtgattaat gcttttactc aaattgaagc ggctaaggct tatttatttg
     1921 caaactctga attttcgggt gcggattggg atacgaaaat ttcaagggat attttctggg
     1981 aagaatctat gcatggtatc tatccagaga atgttggggt caatgctaga ctccttaatg
     2041 atgaagctga tttttttgac tatctaaatc attctgcgat ttttactgcg gaacgtgatg
     2101 ggcagaccta ttatttttat cctattcagg ctggggacta tttggctacg cctgaaatcc
     2161 aagcatttgc tctgaatggg gatgaggtta ttatttcccc ccaagagaag gattttgaaa
     2221 ctcatcgtag ttaccagtac caagacttaa cgactcgagg aacagttgag tttcgtagtg
     2281 tgtgtacaca gccacttgat aggacttttg cttctgcagc ttttcacttg ggattattgg
     2341 ttaatttaga caagttagaa gcttacttag aaacagcacc tttctttaaa gtatttggtt
     2401 atgattacaa gtctttaagg agacaatttt ctaagaaaaa tcttacagat gaggaagaaa
     2461 ctacgattat tgaattttcc aaagacttac tcctactagc tgaggaggga ctagtggtga
     2521 gaaataagga agaaatgacc tatttacagc ctttgagaga agaattgagc ctataatttc
     2581 tcttataaag ggagaatttt ctgaaaaatc atgatataat ggacgagact atagataaag
     2641 gatagagagt aatgacatta gtttatcaat caacgcgtga tgccaacaat acagtaactg
     2701 ccagccaagc aattttgcaa ggtttggcga cggacggcgg tttgtttaca ccggttactt
     2761 atccaaaggt agatttggac tttgacaaat tgaaagatgc ttcttaccag gaagttgcta
     2821 agctagtttt gtcagcattt ttagatgact ttacagctga ggagttggac tactgtatca
     2881 acaatgccta cgatagcaaa tttgatactc cagctattgc actattagtg aaattagatg
     2941 ggcaatacaa tttggaactt ttccatggtt caacgattgc ctttaaggat atggccttgt
     3001 ctattttgcc atactttatg acgactgctg ctaagaaaca tggtttggag aacaagattg
     3061 ttatattgac agcgacatct ggtgacacgg ggaaagctgc tatggcgggg tttgcggatg
     3121 tgcctggtac tgagattatc gtcttttatc caaaggatgg tgtcagcaag attcaagagt
     3181 tacaaatgac cactcagact ggcgacaata ctcatgttat tgctattgat ggtaactttg
     3241 acgatgcgca aacaaatgtg aagcacatgt ttaacgatgt ggctcttcgt gaaaaattga
     3301 ctaccaacaa gttgcaattt tcatcagcta actctatgaa cattggtcgt ctggtgccac
     3361 aaattgttta ttatgtttat gcttacgctc aattggttaa gactggtgaa attgtagctg
     3421 gtgaaaaggt taacttcaca gtaccaacag gaaactttgg aaatatcttg gctgcctttt
     3481 atgccaaaca aattggtttg ccagttggta aattgatctg tgcttcaaat gacaacaatg
     3541 ttttgacaga cttctttaaa acacgtgtct atgacaaaaa acgtgagttt aaggtaacaa
     3601 ccagcccatc tatggatatc ttggtatctt caaacttgga gcgcttgatt ttccatcttt
     3661 tgggaaataa tgctgaaaag acagctgaac tcatgaatgc tttgaacatg caaggacaat
     3721 ataagttgac agactttgat gcagagattc tggagctctt tgcagctgaa tatgcgactg
     3781 aggaagaaac agcggcagaa atcaagcgtg tttatgagtt agattcttat attgaggatc
     3841 cacatacggc ggttgcctca gcagtttata gaaaatacca agcggttact gatgatgcga
     3901 ctaagacagt gattgcttca acagctagtc cctacaagtt cccagtagtt gcagtagaag
     3961 ctgtaactgg aaaagcaggt ttaacagact ttgaagcctt ggctcaatta catgaaatct
     4021 caggcgttgc agtgccacca gcagttgatg ggcttgagac agctcctgtt cgtcacaaga
     4081 caactgtagc ggctgctgat atgcaagcag cggttgaggc ttatttagga ctttaagata
     4141 gagggagtaa actcggttgg gaaaccaact gagtttcttt tcatcaggag gagagattgt
     4201 ttaagaaaaa taaagacatt cttaatattg cattgccagc tatgggtgaa aactttttgc
     4261 agatgctaat gggaatggtg gacagttatt tggttgctca tttaggattg atagctattt
     4321 caggggtttc agtagctggt aatattatca ccatttatca ggcgattttc atcgctctgg
     4381 gagctgctat ttccagtgtt atttcaaaaa gcatagggca gaaagaccag tcgaagttgg
     4441 cctatcatgt gactgaggcg ttgaagatta ccttactatt aagtttcctt ttaggatttt
     4501 tgtccatctt cgctgggaaa gagatgatag gacttttggg gacggagagg gatgtagctg
     4561 agagtggtgg actgtatcta tctttggtag gcggatcgat tgttctctta ggtttaatga
     4621 ctagtctggg agccttgatt cgtgcaacgc ataatccacg tctgcctctc tatgttagtt
     4681 ttttatccaa tgccttgaat attctttttt caagtctagc tatttttgtt ctggatatgg
     4741 ggatagctgg tgttgcttgg gggacaattc tgtctcgttt ggttggtctt gtgattttgt
     4801 ggtcacaatt aaaactgcct tatgggaagc caacttttgg tttagataag gaactgttga
     4861 ccttggcttt accagcagct ggagagcgac ttatgatgag ggctggagat gtagtgatca
     4921 ttgccttggt cgtttctttt gggacggagg cagttgctgg gaatgcaatc ggagaagtct
     4981 tgacccagtt taactatatg cctgcctttg gcgtcgctac ggcaacggtc atgctgttgg
     5041 cccgagcagt tggagaggat gattggaaaa gagttgctag tttgagtaaa caaacctttt
     5101 ggctttctct gttcctcatg ttgcccctgt cctttagtat atatgtcttg ggtgtaccat
     5161 taactcatct ctatacgact gattctctag cggtggaggc tagtgttcta gtgacactgt
     5221 tttcactact tgggacccct atgacgacag gaacagtcat ctatacggca gtctggcagg
     5281 gattaggaaa tgcacgcctc cctttttatg cgacaagtat aggcatgtgg tgtatccgca
     5341 ttgggacagg atatctgatg gggattgtgc ttggttgggg cttgcctggt atttgggcag
     5401 ggtctctctt ggataatggt tttcgctggt tatttctacg ctatcgttac cagcgctata
     5461 tgagcttgaa aggataggaa atgcaaaaaa cagcttttat ttgggattta gacgggactt
     5521 tattggactc ttacgaagcg attttatcag ggattgagga gacttttgct cagttttcta
     5581 ttccttatga taaggagaag gtgagagagt ttatcttcaa gtattcggtg caaaatttgc
     5641 ttgtgcgggt ggcagaagat agaaatctgg atgttgaggt gctaaatcag gtgcgtgccc
     5701 agagtctggc tgagaaaaat gctcaggtag ttttgatgcc aggtgcgcgt gaggtgctag
     5761 cttgggcaga cgaatcagga attcagcagt ttatatatac tcataagggg aacaacgctt
     5821 ttaccattct caaggacttg ggggtggaat cctattttac agagatttta accagtcaga
     5881 gtggctttgt gcggaagcca agtccagaag cggctaccta tctgctagat aagtatcagt
     5941 tgaattctga taatacttat tatatagggg atcggactct ggatgtggaa tttgcccaga
     6001 atagtgggat tcaaagtatc aactttttag agtctactta tgaagggaat cacaggattc
     6061 aagcgttagc agatatttcc cgtatttttg agactaagtg ataaaaagat tgtgtcagtt
     6121 ttgtgacaga gacctaacaa actatttcaa gtaacctagt ttgttacaag gaatagacag
     6181 ttctgttaaa taggcccgag agggcttttt ttctacattt tttgtgttat gatagacagg
     6241 tactaatttg aaaggaattt gaaagaatga agaaaagaat gttattagcg tcaacagtag
     6301 ccttgtcatt tgccccagta ttggcaactc aagcagaaga agttctttgg actgcacgta
     6361 gtgttgagca aatccaaaac gatttgacta aaacggacaa caaaacaagt tataccgtac
     6421 agtatggtga taccttgagc actattgcag aagccttggg tgtagatgtc acagtgcttg
     6481 cgaatctgaa caaaatcact aatatggact tgattttccc agaaactgtt ttgacaacga
     6541 ctgtcaatga agcagaagaa gtaacagaag ttgaaatcca aacacctcaa gcagactcta
     6601 gtgaagaagt gacaactgcg acagcagatt tgaccactaa tcaagtgacc gttgatgatc
     6661 aaactgttca ggttgcagac ctttctcaac caattgcaga agctccaaaa gaagtagcat
     6721 caagttcaga agttacaaag acagtgattg cttctgaaga agtggcacca tctacgggca
     6781 cttctgtccc agaggagcaa acggccgaaa caagcagtgc agttgcagaa gaagctcctc
     6841 aggaaacgac tccaggtgag aagcaggaaa cacaagcaag ccctcaagca gcatcagcag
     6901 tggaagcaac tacaacaagt tcagaagcaa aagaagtagc atcatcaaat ggagctacag
     6961 cagcagtttc tacttatcaa ccagaagaga cgaaaataat ttcaacaact tacgaggctc
     7021 cagctgcgcc cgattatgct ggacttgcag tagcaaaatc tgaaaatgca ggtcttcaac
     7081 cacaaacagc tgcctttaaa gaagaaattg ctaacttgtt tggcattaca tcctttagtg
     7141 gttatcgtcc aggagacagt ggagatcacg gaaaaggttt ggctatcgat tttatggtac
     7201 cagaaagttc agaattaggg gataagattg cggaatatgc tattcaaaac atggccagcc
     7261 gtggcattag ttacatcatc tggaaacaac gtttctatgc tccattcgat agcaaatatg
     7321 ggccagctaa cacttggaat ccaatgccag accgtggtag tgtgacagaa aatcactatg
     7381 accacgttca cgtttcaatg aatggataaa cccgacttgg taacatcatt ttgacgaatg
     7441 agatctagct ttcgtgatag gaagcgattc tcgttcgttt tttctttgtc atactcttcg
     7501 aaaatctctt caaaccacgt cagttttatc tgaaacctca aagctgtgct ttgagcaacc
     7561 tgcgactagc tttctagttt actctttgat tttcattgag tatcaatttg aatggaaaat
     7621 ggaaagttat tatcttgtaa taatccaagc aacattcttg caatctattt tactttatat
     7681 cacaattgat tggtcaacta ttgataagtc aatggatagg aggaagaaat gatagagatt
     7741 caagatttac tgtatcaact ccgcttgtct gagcaagcga gtacgcaatt gtttgaaaaa
     7801 ggcttgggat tagtttgaca cggtatcaga ttttactgtt tttgctggag cattctcctt
     7861 gtaaccaaat ggcggttcag gagcgtttga aaattgatca ggctgctttg acacggcatt
     7921 tcaagatttt ggaaacggaa ggtttggtgg agcgtcatcg taatcctgaa aatcagcggg
     7981 aagtgttggt agaggctgcg aagtatgcca aggagcagtt agtggtgaat ccccctctgc
     8041 aacatatcaa ggttaaggaa gagatggaaa gtatcttaac agagtttgag agaacagaac
     8101 tcagccgttt attaaataaa ttggttttgg gtattgaaaa tatagaaatt taaggagaaa
     8161 tagatgtcaa ttattttaac aacgatcgtt gctttggagc atttttacat tttttatttg
     8221 gaaagtattg ccacgcaatc agatgcgact agtcgtgtat ttaatatgga aaaggaagaa
     8281 ttggctcatc cgtcagtaag ttcattgttc aaaaatcaag gaatttataa ggctctgcta
     8341 ggagtctttc tcttgtatgt catttatttc tcacagaatt tagaaattgt gactattttt
     8401 gtcttatttg tgattggtgc tgcgacttac ggctctttaa cagcggataa aaaattattt
     8461 tgaagcaagg tggatcagct attttggcct tgattagtat tttactcttt aaatacactt
     8521 gaaggttgat tctaatctcg ctaatccttt ttaatccaga ataagggaaa tatgttatac
     8581 ttgtttttaa gaaaaaagtc tcattgaatt ggttttgagg agttagaaat gaaagtatta
     8641 gtgacaggtt ttgagccctt ttgaggccat taaaggttta ccagctgaaa tccatggtgc
     8701 tgaggtccgt tagctagagg tgccgacagt ttttcacaaa tctgctcaag tattggaaga
     8761 agagatgaat cgttatcaac ctgactttgt cctttgtatt gggcaagctg gtggaagaac
     8821 tagtttgaca cctgaacgag tggccattaa tcaagacgat gcacgcattt ctgataacga
     8881 agataatcaa ccgattgacc gtcccattcg cccagatggt gcttcggcct actttagtag
     8941 tttgccgatt aaagcgatgg ttcaagctat aaaaaagagg gcttaccggc ctctgtttcc
     9001 aatacggcag ggacttttgt ctgcagccat ttgatgtatc aggctctcta tttggtagaa
     9061 aagaaatttc catatgttaa ggcaggtttt atgcatattc cttatatgat ggaacaggtg
     9121 gtgaacagac agactattcc agctatgagt ttagtggata ttcggagagg gatagaagca
     9181 gcaatcggcg ctatgataga acatggagat caggaactca agttggtagg cggagaaact
     9241 cattgataga aaaaagcttg agtggaaaaa ccttcaagct tttggacgtt ttcgagccaa
     9301 tactgctcgg taaaacataa ttttagtgca ttggatataa ggtaggagtg aaaaactagc
     9361 aatgccaaag gtaatccaat tgaggaagta ccaaggaaga agctgtaaat ctaggacaaa
     9421 gcgctggaac ttgtagccct tcataaagga acggctagtt tttaggattc gtcttggtgg
     9481 gacctgtcct aggtctagac tataacagag aagaaattcc acctgtgaat aggcataata
     9541 ctgtggaata tagaggatat ttcctacaat gatcaagatg agacttgcaa gaaagtagag
     9601 tccaaagacc atgaggaaac gctcggtttc aactgatgag agatctagat ttggaaactc
     9661 aggatgtagg gtgacgaatt ttttggctaa aaagctacta taaaagagga ggtaaatccc
     9721 aagtaaatta gggatactcc ataaaaagag atagaaacgt ttgagaagta gggtcaaaaa
     9781 ggtttgagaa aagcgctcct catcaaagag agctaggctg ttttttacag atggctccgt
     9841 tttagaatct ttcatgagtg tcagtgttgc atagacggaa ctggtcaaaa gaatagtccc
     9901 gataaagaag actagtagag gaaagaggta ggcttgaagt atttggccaa gtatgctgaa
     9961 aaatggctgt tctaaaacag tcccgtggat ccgagataag ggattaagaa aactagataa
    10021 gatgaccagc atactgggaa ggatatagag gagaaagaga cggggggtgt cagcctgaaa
    10081 atgttttgac tcctgacgaa ttgtttttaa atcaattttt ggatagttca ttctcttatt
    10141 ataccatagt tcttatacat agttcgtgac agttcctact ttttttgata aaatcataca
    10201 gtgtgtcctt gggcacactg tatgaactgg gactgtcttt cccagcttcg gaggtaaaaa
    10261 atgtcagatt caccaatcaa atatcgtttg attaagaaag aaaaacacac aggagctcgt
    10321 ctgggagaaa tcatcactcc ccacggtacc tttccgacac ctatgtttat gccagttggg
    10381 acacaagcca ctgtcaaaac tcagtcacct gaagaattga aggagatggg ttcgggaatt
    10441 atcctatcaa acacctatca tctctggctt cgccctggag atgaactcat tgcacgcgct
    10501 ggtggtctcc acaagttcat gaattgggac cagcctatct tgacagatag tggtggtttt
    10561 caggtttatt ctttagcaga tagccgtaat atcacagaag aaggagtaac ctttaaaaat
    10621 catctaaatg gttctaagat gttcctatcc ccagaaaaag ccatctctat tcagaataat
    10681 ctgggttcag acatcatgat gtcctttgat gaatgtcctc agttttatca accttatgac
    10741 tacgttaaga aatcgatcga gcgtaccagc cgttgggctg agcgtggttt gaaggctcac
    10801 cgtcgtccac atgaccaagg tttgtttgga attgtgcaag gtgcaggatt tgaagacctt
    10861 cgccgccaat cagctcatga tcttgtcagc atggatttct caggctactc tatcggtggt
    10921 ttggcagtgg gagaaaccca tgaagagatg aatgcggtct tggactttac aactcaactg
    10981 ctacctgaaa ataaacctcg ttatctgatg ggtgtgggag cgccagatag cttgatcgat
    11041 ggggtcattc gtggggtgga tatgtttgac tgtgtcttac cgactcgaat tgctcgtaac
    11101 gggacttgta tgaccagtca aggacgtttg gttgtgaaaa atgcccagtt tgctgaggac
    11161 tttacgccac tggatcctga gtgtgactgc tacacatgta ataactatac acgcgcttac
    11221 cttcgtcacc tgctcaaggc tgatgaaacc tttggtatcc gcttgactag ctaccacaat
    11281 ctttacttct tgcttaacct gatgaagcaa gtgcgacaag ccatcatgga tgacaatctc
    11341 ttggaattcc gtgagtattt tgtggaaaaa tatggctata ataagtcagg acgtaatttc
    11401 taaaatggaa ttgatataaa aaaatcctaa gttttctctt aggatttttc ttcttttttt
    11461 gatagaataa agtgtacaat gaaaggaaga ataaactcgt atgcgcatta aatggttttc
    11521 cttgattagg attataggtt tacttttggt actcttgtat cacttctttc agacgatctt
    11581 tcctggagga ttcttcgggg tagatgtctt tttcacattt tcaggtttcc tgattacagc
    11641 tctactcatt gaagaatttt ctaagaacaa tgagattgat ttgataggat tttttagaag
    11701 acgcttttat cggattgtgc cacctgtggt tttgatggtc ttggtgacca tgccttttac
    11761 tttcttggtt cgccaagact atgttgctgg aattggtggc cagattgcgg gcgtcttagg
    11821 ctttatgacc aacttctatg aactcctaac aggtgggagt tatgaatctc agttcattcc
    11881 tcatttgttt gttcataatt ggagtttggc agttgaggtt cactactata ttctttgggg
    11941 attggcagtt tggttcttat ccaaacaagc taaatcaaat ggtcagttga aggggatggt
    12001 ctttctctta tctgctgctg ccttcttgat cagtttcttc tccatgttta ttggtagttt
    12061 tctagtgacc tcttattcct ctgtttattt ctccagttta actcatgtct atccattctt
    12121 tttgggaagt atgttagcaa ctattgtagg cgttcgtcag acgacttccc tcgtcaagca
    12181 gttggataaa atctgggatt tacgaaagac tttggtagtt tttggaggag gctttggttt
    12241 cctagttctt ttgactttct ttgtcaaatt cacttatctt tttgcctatc ttatcggctt
    12301 cttgcttgcc agtcttgcag ctcttgccat gattctggcg gcgcgtgtct tacatgaaaa
    12361 gacacatcat atacaggagc cgaagattat cagcttttta gcggatacta gctatgcggt
    12421 ttatcttttc cattggcctt tctatatcat tttctcacag ttgacatcaa atcttcttgc
    12481 tgtattactg actctgattt gttcttatgg ctttgccagt ctgtcattct atgtattgga
    12541 accttggatt gcaggcaaga acacacctat tttacaaact cttcgtcccc tgccttatat
    12601 tcacgcaatt cttgcagcag gtacaggaat cttgaccttc attgtctgca tggtgacctt
    12661 gttggcacca caagtgggag cgtttgagac agacttgact gtcaatggct tgaagcaagc
    12721 tgcaacaaat attggccaga ccaaggtgat ggcagaacgg gcagatgcaa acagtttggg
    12781 aattgctgat ggcactatgt taattggtga ctcagtggct ttaagggcaa atacagcact
    12841 acagacagtt cttcctggag cacagattaa cgcgcaggtc agcgtaacaa ccaagaccgc
    12901 aaatgaaatc atgctaaata atagccagaa taaattttta cctaagacgg tggtcattgc
    12961 gactggggta aataatcctg agaattacaa ggatgactgg gacagtatcg tgaaaaatct
    13021 tcctaaggga caccatatga ttttggtgac tccttatgag ggagataaga caaaagagac
    13081 ctatgccatc gttgagaagg ctgctgccta tatgagagaa ttggcagaga agacacctta
    13141 cattacgata gcagattgga atcaagttgc gaaagagcat ccagaaattt gggcaggaac
    13201 agaccaggtt catttcggga gtgagagtag cactatcgaa gcaggagcaa aattgtatgc
    13261 agatacgatt gccacagctt tgcagacagc tcaagacaag ccggttaaat caaaataact
    13321 tgtattaaaa aagagaagag ttggagaaat ccagctcttt taaaatatct ccaaaaaata
    13381 ggtctatacc atttacaaat aaaaaagaaa ggtttataat gtaattgaca taataaattg
    13441 tagaatcaat cttttaagga ggttaacatt atgcctaact atattaaagc ggatcagttt
    13501 ttctacccac acggagttcg tcgaggtggt tacttggaac ttgtggacgg caagtttggg
    13561 aaacatgtag agcagattcc tgaaggggct gaggtgattg actatacagg ttatagcatt
    13621 gccccaggtc ttgtggatac tcatattcat ggatatgcag gtgtagatgt gatggacaac
    13681 aacattgaag gtacattgca tactatgagt gaaggacttc ttagtaccgg tgttaccagt
    13741 ttcttaccca caactttaac agccacttat gagcaattgc ttgcagtcac tgaaaatctt
    13801 ggaaaccatt ataaagaagc aacaggtgct aagattcgtg ggatttatta tgaaggtcca
    13861 tatttcacag aaacttttaa gggggcacaa aatccaactt atatgagaga cccgggtgtt
    13921 gaggagtttc attcttggca aaaagcggca aatggcttgc ttaataaaat tgcccttgca
    13981 ccagaacgtg atggggtgga agactttgtt cgtacagtta cgggcgaagg tgtgacggtt
    14041 gctcttggac attcaaacgc gacttttgat gaagccaaaa aagcagtcga tgctggagcg
    14101 agtgtttggg tgcatgccta caatggaatg cgtgggttga ctcaccgtga attgggtatg
    14161 gttggagcca tgtaccaatt gccacatacc tatgcagagt tgatctgtga tggtcaccac
    14221 gtagatccaa aggcttgcga aattcttatc aaacaaaaag gaacagaaaa catcgctctt
    14281 atcacagact gtatgacagc tgggggattg gaagacggag attatatgtt gggagaattc
    14341 ccagttgtcg ttgcaaatgg aactgcacgc ctcaaatcga caggtaactt ggcaggttct
    14401 atcctcaaac tcaaagatgg tttgaagaat gtggtcgaat ggggaattgc gaatccgcat
    14461 gaagcagtca tgatggccag cttcaaccca gctaaatccg ttcacatcga tgacgtctgt
    14521 ggccaaatcc gtgaaggcta cgacgctgac ttcatcgtat tagataaaga tttggaattg
    14581 gtagcaacct acctagatgg cgtgaaacgt tatcaagcat aagagagaaa gcagaagtta
    14641 gagactaact tctgcttttt tatgcagggt actttactgg taaataaaaa gttaaaaaaa
    14701 tcacaaaaaa agcttgaaga aacaaagaaa aaggcttaca attgaactat aaatattaca
    14761 aataaaaaaa cggaggagtg ctttatgaaa gcttatactt atgttaaacc aggacttgct
    14821 tcttttgttg atgtagacaa accagttatt cgcaagccaa cagacgctat tgtgcgtatt
    14881 gtaaaaacca ctatttgtgg aacagacctc catattatca aaggggatgt tcctacttgc
    14941 caaagtggta ccattcttgg ccacgaaggg attgggattg ttgaagaagt tggggaagga
    15001 gtttccaact tcaaaaaagg tgacaaggtc ttgatttctt gcgtctgtgc ctgtggtaaa
    15061 tgctactact gtaaaaaagg aatttatgcc cactgtgaag acgaaggggg ctggattttc
    15121 ggtcacttga ttgatggtat gcaggctgaa tatctacgtg tccctcatgc agataatact
    15181 ctttaccata ctccagaaga cttgtcagat gaagctttgg ttatgctgtc agacattctg
    15241 cctactggat atgaaattgg tgtcttaaaa gggaaagtag aacctggttg cagcgtagcc
    15301 attattggtt caggtccagt tggattggct gctcttttaa cagcccaatt ctattcacca
    15361 gctaaattga ttatggtaga cctagacgat aaccgtttgg aaactgccct atcattcggt
    15421 gcgactcata aggtaaactc ttcagaccct gaaaaagcga taaaagaaat ttatgatttg
    15481 acagatggtc gcggtgtaga tgtcgctatt gaagctgtag ggattcctga aacatttgat
    15541 ttctgtcaaa agattatcgg tgtagacgga acggttgcca actgtggtgt gcatggtaaa
    15601 ccagttgaat tcgatttaga taaactttgg attcgtaaca tcaatgtaac aactggtttg
    15661 gtatctacaa atacgactcc acaattgttg aaagcacttg aaagtcataa gattgaaccg
    15721 gaaaaattgg taactcacta tttcaaactc agtgaaattg aaaaagccta cgaagtcttc
    15781 agtaaggcag cagaccacca tgccattaag gtcattatcg aaaacgatat ctcagaagcc
    15841 taagtagtaa aaatattttt gtacataagc aaatagaaat tcagtcatcc atcagatggc
    15901 tggatttttt atcaaaaaat taagaaatga gcatatttct ttccttgtct ggcggaattg
    15961 gttataatat acggtacaaa ggaatgaatg aatatgtatc gtgttataga aatgtacgga
    16021 gattttgaac cgtggtggtt cttagaaggt tgggaagaag atattgtagc aagtagaaaa
    16081 tttgaccagt attatgatgc tctcaaatac tacaaaactt gctggtttag attagaacaa
    16141 gaatcccctc tttataaaag tagaagcgac ttgatgacca ttttttggga cccggaagac
    16201 caacgctggt gtgatgaatg tgatgagtat ttacaacaat accattcttt ggctcttttg
    16261 caggatgagc aggttatccc agacgaaaaa ctacgctcag gctatgaaaa acaaaccagt
    16321 caggaaagga atcgttcttg ccgtatgaaa ttaaaataga gaaaagtaac ttttttggag
    16381 ttgctttttt tatttttcta acgctttgcg aatagtatag gtgaggaggt aagtatggtt
    16441 caagaaattg cacaagaaat cattcgttcg gctcggaaaa aaggggcgca agacatttat
    16501 tttgtcccta agttagatgc ctatgagctt catatgaggg taggagacga gcgctgtaaa
    16561 attggtagct atgattttga aaagtttgca gccgttatca gtcactttaa gtttgtggcg
    16621 ggtatgaatg tgggagaaaa aagacgtagt caactgggtt cctgtgatta tgcctatgac
    16681 cagaagatgg cgtctctacg tttatctact gtaggcgatt atcgggggca tgagagtttg
    16741 gttatccgtt tgttgcacga tgaggagcag gacttgcatt tttggtttca ggatattgaa
    16801 gaattaggca agcagtacag gcaacgggga ctctatcttt ttgctggtcc ggttgggagt
    16861 ggtaagacga ccttgatgca tgaattgtcc aagtcactct ttaaaggaca gcaagttatg
    16921 tccatcgaag atcctgtcga aatcaagcag gacgacatgc ttcagttgca gttgaacgaa
    16981 gcaatcggcc taacctatga aaatctaatc aaactttcct tgcgtcatcg accagatctc
    17041 ttgattatcg gagaaattcg tgacagcgag acggcgcgtg cagtggtcag agctagtttg
    17101 acaggtgcga cagtcttttc aaccattcac gccaaaagta tccgaggtgt ttatgagcgt
    17161 ctgctggagt tgggtgtgag tgaagaagaa ttggcagttg ttctgcaagg agtctgctac
    17221 cagagattaa tcgggggagg aggaatcgtt gactttgcaa gcagagatta tcaagaacac
    17281 caagcagcca agtggaatga gcaaattgac cagcttctta aagatggaca tatcacaagt
    17341 cttcaggctg agacggaaaa aattagctac agctaagcaa aaaaatatca tcaccctatt
    17401 taacaatctc ttttctagcg gttttcatct ggtggagacc atctcctttt tagataggag
    17461 tgctttgttg gacaagcagt gtgtgaccca gatgcgtgtg ggcttgtctc aggggaaatc
    17521 attctcagaa atgatggaaa gtttgggatg ttcaagtacc attgtcactc agttatctct
    17581 agctgaagtt catggcaatc ttcacctgag tttgggaaag atagaagaat atctagacaa
    17641 tctggccaag gtcaagaaaa agttaattga agtagcgacc tatcctttga ttttgctggg
    17701 ttttcttctc ttaattatgc tggggctacg gaattacctg ctcccacaac tggatagtag
    17761 caatattgcc acccgaatta tcggtaatct gccacaaatt tttctaggca tggtagggct
    17821 tgtttccgtg cttgcccttt tagcactaac tttttataaa agaagttcta agatgagtgt
    17881 cttttctatc ttagcacgcc ttccctttat tggaatcttt gtgcagacct acttgacagc
    17941 ctattatgca cgtgaatggg ggaatatgat ttcacaggga atggagctga cgcagatttt
    18001 tcaaatgatg caggaacaag gttcccagct ctttaaagaa atcggtcaag atctggctca
    18061 aaccctgaaa aatggccgtg aattttctca gacgatagga acctatcctt tctttaggaa
    18121 ggaattgagt ctcatcatag agtatgggga agttaagtcc aagctgggta gtgagttgga
    18181 aatctatgct gaaaaaactt gggaagcctt ttttacccga gtcaaccgca ccatgaattt
    18241 ggtgcagcca ctggttttta tctttgtggc actgattatc gttttacttt atgcggcaat
    18301 gctcatgccc atgtatcaaa atatggaggt aaatttttaa aatgaaaaaa atgatgacat
    18361 tcttgaaaaa agctaaggtt aaagctttta cattggtgga gatgttggtg gtcttgctga
    18421 ttatcagcgt gcttttcttg ctctttgtac ctaatctgac caagcaaaaa gaagcagtca
    18481 atgacaaagg aaaagcagct gttgttaagg tggtggaaag ccaggcagaa ctttatagct
    18541 tggaaaagaa tgaagatgct agcctaagca agttaaaaga cgatgggcga atcacggaag
    18601 aacaggttaa agcttataaa gaatacaatg ataaaaatgg aggagcaaat cgtaaagtca
    18661 atgattaagg cctttaccat gctggaaagt ctcttggttt tgggtcttgt gagtatcctt
    18721 gccttgggct tgtccggctc tgttcagtcc acttttgcgg cagtagagga acagattttc
    18781 tttatggaat ttgaagaact ctatcgggaa acccaaaaac gcagtgtagc cagtcagcaa
    18841 aagactagtc tgaacttaga tgggcagatg attagcaatg gcagtcaaaa gttgccagtc
    18901 cctaaaggaa ttcaggcccc atcaggccaa agtattatat ttgaccgtgc tgggggcaat
    18961 tcgtccctgg ctaaggttga atttcagacc agtaaaggag cgattcgcta tcaattatat
    19021 ctaggaaatg gaaaaattaa acgcattaag gaaacaaaaa attagggcag tgattttact
    19081 ggaagcagta gtcgctctag ctatctttgc cagcattgcg accctccttt tgggacaaat
    19141 tcaaaaaaat aggcaagagg aagcaaaaat cttgcaaaag gaagaagtct tgagggtagc
    19201 taagatggcc ttgcagacgg ggcaaaatca gataaacatc aacggagttg agattcaggt
    19261 attttctagt gaaaaaggat tggaggtcta ccatggttca gaacagttgt tggcaatcaa
    19321 agagccataa ggtcaaggct tttaccttgt tagaatccct gcttgccctg cttgtcatca
    19381 gtgggggctt actccttttt caagctatga gtcagctcct catttcagaa gttcgctacc
    19441 agcaacaaag cgagcaaaag gagtggctct tgtttgtgga ccaacttgag gcagaattag
    19501 accgttcgca gttcgaaaaa gtagaaggca atcgcctata catgaagcaa gatggcaagg
    19561 acatcgccat cggtaagtca aagtcagacg attttcgtaa aaccgatgct agtggacgag
    19621 gttatcagcc tatggtttat gggctcaaat ccgcacagat tacagaggac aatcaactgg
    19681 tgcgctttcg tttccagttt caaaaaggct tagaaaggga gttcatctat cgtgtggaaa
    19741 aagaaaaaag ttaaggcagg tgttctcctc tacgcagtca ccatagcagc catctttagt
    19801 cttttgttgc aattttattt gaaccgacaa atcgcccact atcaagacta tgctttaaat
    19861 aaagaaaaat tggttgcttt tgccatggct aaacgaacca aggataaagc cgagcaagaa
    19921 agtggggaac aggtctttaa tctaggtcag gtaagctatc aaaacaagaa aacaagcttg
    19981 gtgacgactg ttcgtacgtc taagagccaa tatgagtttc tgtttccttc agtcaaaatc
    20041 aaagaagaga aaagagataa aaaggaagag gtagcgaccg attcaagcga aaaagtggag
    20101 aagaaaaaat cagaagagaa gcctgaaaag aaagagaatt cctagtcaat tcaactataa
    20161 tgcgttgaat ccagaatagt tcactgtagt ttctagaaaa ttgctggaaa tggatgttaa
    20221 gctccaattt atttgtttat atcttatttc agtttactat actttgtgct aaactaaaga
    20281 tatgaaacat gattttaacc acaaagcaga aactttcgat tcccctaaaa atatcttcct
    20341 cgcaaacttg gtatgtcaag cagtcgagaa acagattgat attttatcag acaaagaaat
    20401 tttagatttc ggtggtggca cgggtctatt agccttgccc ctagccaagc aggctaagtc
    20461 agttactctt gtagacattt ctgagaaaat gttggagcaa gctcatttga aagcggagca
    20521 gcaagcaatc aagaatatcc agtttttgga gcaagattta ccgaaaaatc ccttggagaa
    20581 agagtttgat tgccttgctg ttagtcgggt tcttcatcat atgcctgatt tggatgcggc
    20641 tctctcactg tttcatcaac atttgaagga agatgggaaa ctcatcattg ctgattttac
    20701 caagacagaa gctaatcatc atggatttga tttagctgaa ctggaaaaca agctaattga
    20761 gcatggtttt tcatctgtgc atagtcagat tctctatagc gctgaagact tgtttcaagg
    20821 aaatcactca gaattctttt taatagtagc ccaaaaatca ctcgcctagt cagggagtga
    20881 tttttctata aggatggaaa aaagaaggga aatttgataa gataggaata tggattttga
    20941 aaaaattgaa caagcttata cctatttact agagaatgtc caagtcatcc aaagtgattt
    21001 ggcgaccaac ttttatgacg ccttggtgga gcaaaacagc atctatctgg atggtgaaac
    21061 tgagctaaac caggtcaaag acaacaatca ggcccttaag cgtttagcac tacgcaaaga
    21121 agaatggctc aagacctacc agtttctctt gatgaaggct gggcaaacag aacccttgca
    21181 ggccaatcac cagtttacac cggatgctat tgctttgctt ttggtgttta ttgtggaaga
    21241 gttgtttaaa gaggaggaaa ttactatcct cgaaatgggt tctgggatgg gaattctagg
    21301 cgctactttc ttgacctcgc ttgataaaaa ggtggattac ttgggaatgg aagtggatga
    21361 tttactgatt gatctggcag ctagcatggc agatgtaatt ggtttgcagg ctggctttgt
    21421 ccaaggagat gccgttcgtc cacaaatgct caaagaaagc gatgtggtca tcagtgactt
    21481 gcctgtcggc tattatcctg atgatgccgt tgcgtcgcgt catcaagttg cttctagcca
    21541 agaacatact tacgcccatc acttgctcat ggaacaagga tttaagtacc ttaagtcaga
    21601 tggatatgct atttttctag ctccgagtga tttgttgacc agtcctcaaa gtgatttgtt
    21661 gaaagtctgg ttgaaagagg aggcaagtct ggttgctatg attagtctgc ctgaaaatct
    21721 ctttgctaat gctaaacaat ctaagactat ttttatccta cagaagaaaa gtgaaatagc
    21781 agtggagctt tttgtttatc cacttgctag cttgcaagat gcaagtgttt taatgaaatt
    21841 taaagaaaat tttcaaaaat ggactcaagg tactgaaata taaaatagat tttgttataa
    21901 tagttgaaaa cgcttaaaaa ggggtatcat gttatgacaa aaacaattgc aatcaatgca
    21961 ggaagttcaa gcttaaaatg gcaattatac ttaatgccag aggaaaaagt attggcgaaa
    22021 ggcttgattg aacgtatcgg tttgaaagat tcaatttcaa ctgtaaaatt tgacggccgt
    22081 tctgaacaac aaattttgga tatcgaaaat catacacaag ccgttaaaat tttattggat
    22141 gacttgattc gtttcgatat tatcaaggct tatgacgaga ttacaggtgt tggccaccgt
    22201 gttgtagcag gtggagaata tttcaaagaa tcaacagttg ttgagggaga tgttttagaa
    22261 aaagttgaag agttgagttt gttggctcct ctacacaacc cggccaatgc agcaggtgtt
    22321 cgtgccttca aggaattgtt gccagacatt accagtgtag ttgtttttga tacttccttc
    22381 cacacaagta tgccagagaa agcttatcgc taccctctac caacaaaata ttacacagaa
    22441 aacaaggttc gtaaatacgg tgctcatggt acaagtcacc agtttgtagc aggagaagct
    22501 gcaaaactct tgggacgtcc attagaagac ttgaagttaa ttacctgtca tattggtaac
    22561 ggaggctcaa ttacagctgt gaaagccggc aaatctgtag acacttctat ggggttcact
    22621 cctcttggtg gtattatgat gggaacgcgt acaggggata ttgatccagc tatcattcct
    22681 tatttaatgc aatatacaga ggattttaac acaccagaag atatcagtcg tgttcttaac
    22741 cgtgaatcag gtcttttggg agtttctgct aattctagcg atatgcgcga tatagaagca
    22801 gctgtagcag aagggaatca cgaggctagc ttggcttatg aaatgtatgt tgaccgtatc
    22861 caaaaacata tcggtcagta ccttgcagtg ctaaatggaa cagatgccat tgttttcaca
    22921 gcaggtgtcg gtgaaaatgc agagaatttc cgtcgtgatg taatctcagg gatttcgtgg
    22981 tttggttgtg atgttgatga tgaaaagaat gtctttggcg ttacaggaga catctcaaca
    23041 gaggcagcta aaatccgtgt cttggttatt ccaacagatg aagaattagt cattgcccgt
    23101 gacgttgaac gcttgaaaaa ataagtgaaa ctaaaaaaat attcaataca aggagttggg
    23161 aaagttattt ttccagcttc tttttctgat gaaattgtcc aaaaccttgc tatgattggc
    23221 ttttttgaaa aatatggtat aatagtagta atttaataga tggagttgag ttttgaagaa
    23281 aaactttcgt gtaaaaagag agaaagattt taaggcgatt ttcaaggagg ggacaagttt
    23341 tgctaatcgc aaatttgtgg tctaccaatt agaaaaccag aaaaaccatt ttcgagtagg
    23401 tctatcagtt agcaaaaaac tggggaatgc cgtcactaga aatcaaatta agcgacggat
    23461 tcggcatatt atccagaatg caaaagggag tctggtagaa gatgtcgact ttgttgtcat
    23521 tgctcgaaaa ggagtcgaaa ccttgggata cgcagagatg gagaaaaatc tactccatgt
    23581 attaaaatta tcaaagattt accgggaagg aaatgggagt gaaaaagaaa ctaaagttga
    23641 ctagtttgct aggactgtct ctgttaatca tgacagcctg tgcgactaat ggggtaacta
    23701 gcgatattac agccgaatcg gctgattttt ggagtaaatt ggtttacttc tttgcggaaa
    23761 tcattcgctt tttatcgttt gatattagta tcggagtggg gattattctc tttacggtct
    23821 tgattcgtac agtcctcttg ccagtctttc aggtgcaaat ggtggcttct aggaaaatgc
    23881 aggaagctca gccacgcatt aaggcgcttc gagaacaata tccaggtcga gatatggaaa
    23941 gcagaaccaa actagagcag gaaatgcgta aagtatttaa agaaatgggt gtcagacagt
    24001 cagactctct ttggccgatt ttgattcaga tgccggttat tttggccctg ttccaagccc
    24061 tatcaagagt tgacttttta aagacaggtc atttcttatg gattaacctt ggtagtgtgg
    24121 atacaaccct tgttcttccg attttagcag cagtattcac ctttttaagt acttggttgt
    24181 ccaacaaagc tttgtctgag cgaaatggcg ctacgactgc gatgatgtat gggattccag
    24241 tcttgatttt tatctttgca gtttatgcgc caggtggagt cgccctatac tggacagtgt
    24301 ctaatgctta tcaagtcttg caaacctatt tcttgaataa tccattcaag attatcgcag
    24361 agcgcgaggc cgtagtacag gcacaaaaag atttggaaaa tagaaaaaga aaagccaaga
    24421 aaaaggctca gaaaacgaaa taaataagga ggaatctggt aatggtagta tttacaggtt
    24481 caactgttga agaagcaatc cagaaaggat tgaaagaatt agatattcca agaatgaagg
    24541 ctcatatcaa agtcatttct agggagaaaa aaggctttct tggtctattt ggtaaaaaac
    24601 cagcccaagt ggatattgaa gcgattagtg aaacgactgt tgtcaaagca aatcaacagg
    24661 tagtaaaagg cgttccgaaa aaaatcaatg atttgaacga gcctgtgaag acggttagtg
    24721 aagaaaccgt tgaccttggt catgtagttg atgctattaa aaaaatagag gaagaaggtc
    24781 aaggtatttc tgatgaagtc aaggctgaaa tcttaaaaca tgaaagacat gccagcacta
    24841 tcttagaaga aactggtcac attgagattt taaatgaact tcaaatcgag gaagcgatga
    24901 gggaagaagc aggcgctgat gaccttgaaa ctgagcaaga ccaagctgaa agtcaagaac
    24961 tagaagactt gggcttgaaa gttgaaacga actttgatat tgaacaagta gctacggaag
    25021 taatggctta tgttcaaacg attattgatg acatggatgt tgaggctaca ctttcaaatg
    25081 attataaccg tcgtagcatc aatttgcaaa ttgatactaa cgaaccaggt cgtattatcg
    25141 gctaccatgg taaagtcttg aaggccttgc aactgttggc tcaaaattat ctttacaact
    25201 gctattcaag aaccttctat atcactatta atgtcaatga ttatgttgaa caccgtgcag
    25261 aagtcttgca gacctatgcg caaaaattgg cgattcgtgt tttagaagaa ggacgcagtc
    25321 atcaaacaga tccaatgtcg aatagtgaac gcaagattat ccaccgtatt atttcacgta
    25381 tggatggcgt gaccagttac tctgaaggtg atgagccaaa tcgctatgtc gttgtagata
    25441 cagaataagt aaaatcaggg ttgacctgat tttttgctag ctagaggagg ttaaactgat
    25501 gttgaataag ataagagact atctagactt ttctggtttg cagtaccgta gtcctgataa
    25561 agcgggagca gagcgagaga agatgctggc attccgtcac aaaggacaag aggcccgaaa
    25621 ggcttttaca gaactggcca aagcctttca agcaagccat ccagaatggc aactccaaca
    25681 gactagtcag tggatgaatc aggcccagcg tttgagacca catttttggg tttatctaca
    25741 gagagacgga caagtgacag aacctatgat ggccttacgt ttgtatggga catctactga
    25801 ctttggaatt tctttggaag tcagtttcat cgaacgtaag aaggatgagc aaactttaga
    25861 gaaacaggcc aagattttag acattccaac cgttaaagga atttattatc tagcctactc
    25921 tgatggccaa agtcaacggt gggaggcgaa cgaagaaaag cgtcgtactt tacgcgagaa
    25981 ggtgagaagt caagaagttc gaaaagtttt agtgaaggta gatgttccta tgacagaaaa
    26041 ttcgtctgaa gaagaaatcg tagaaggctt attgaagtct tattctaaaa ttcttcccta
    26101 ttatctagct acgagaaaat aagataattt gtaaaacatc ataaatcata cagtccaaga
    26161 gtgaacagtc cgctgtgtaa ttcttggtct ttttgtttgc gctttcgcat tatataataa
    26221 acttacaaaa acaattcaaa aggagaacaa ttatggaagt catttcaagt gttctaaatt
    26281 ggttttctag caatattttg cagaatcccg catttttcgt aggtttattg gtgttgatag
    26341 gatatgcact tttgaaaaaa cctgcccatg acgttttttc agggtttgtt aaagcaacag
    26401 tagggtatat gttgcttaac gtgggtgctg gtggtttggt tacaaccttt cgtccaatct
    26461 tagcagctct taactacaaa ttccaaattg gtgcagcggt tatcgaccct tactttggac
    26521 ttgctgcagc aaacaacaaa attgcagcag agtttccaga ttttgttgga actgcaacta
    26581 cagctctatt gattggtttt ggaataaata tcttgctcgt agctcttcga aagattacga
    26641 aggtaagaac cctctttatt actggtcaca tcatggtaca acaagctgca acagtatctc
    26701 ttatggttct attcttagta ccacaattgc gcaatgctta cggtacagca gcgattggta
    26761 tcatctgtgg actttactgg gcagttagtt caaatatgac tgttgaggca actcaacgct
    26821 tgactggtgg tggcggattt gcgattggtc accaacagca atttgcaatc tggtttgtag
    26881 ataaagtagc aggacgcttt ggtaagaaag aagaaagttt agacaatctt aaattaccta
    26941 agttcctctc aatcttccac gatacagttg ttgcatctgc taccttgatg ctcgtattct
    27001 tcggagccat tcttttaatc ttgggtccag acattatgtc taataaagaa gtcatcactt
    27061 caggaactct attcaatcct gctaaacaag atttctttat gtacattatc caaacagcct
    27121 ttaccttctc agtttacttg ttcgttttga tgcaaggtgt ccgaatgttc gtatctgagt
    27181 tgacaaacgc cttccaaggt atttcaaaca aattgttgcc aggttcattc ccagcggttg
    27241 acgttgcagc ttcttatgga tttggttctc caaatgctgt cctgtcagga tttatctttg
    27301 gtttgattgg tcaattgatt acaattgttt tgctcatcgt ctttaaaaat ccgattctta
    27361 ttattacagg atttgtacca gtgttctttg acaatgcagc cattgcggtc tacgctgata
    27421 aacgcggcgg atggaaagcg gctgttatcc tttcctttat atcaggtgtc cttcaagttg
    27481 ctctaggagc tctttgtgtg gcccttctcg atttggcatc ttatggtggc taccatggaa
    27541 atatcgactt tgaattccca tggcttggat ttggatatat cttcaaatac cttggtattg
    27601 ttggttatgt acttgtgtgt ctcttcttgc ttgttattcc tcaacttcaa tttgccaaag
    27661 caaaagataa agagaaatat tacaacggtg aagttcaaga agaagcttag tatctagaaa
    27721 aggagaaata aaatggttaa agtattagca gcgtgcggaa atggaatggg ttcatcaatg
    27781 gttatcaaga tgaaggttga aaatgctctc cgtaagctta atcaaacaga ttttacagtc
    27841 aattcatgca gtgtcggtga agctaaaggt ttagcagtag gatatgacat cgtaatcgct
    27901 tctcttcatt tgattcaaga attggaaggg cgaactaatg ggaagttaat tgggcttgat
    27961 aacttgatgg atgataaaga aatcaccgaa aaactcagtc aagcactaca gtaaaaggtt
    28021 ggagggggct ggacagaaac tgagagttat cgtttctgtc cttctccctc tttaaataaa
    28081 ggaggcagat atgaatttaa aacaagcttt aattgacaac gactcgatcc gactaggttt
    28141 agaggctaac gattggaaag aagcagtcaa ggtagcagta gatcccttga ttgaaagtgg
    28201 ggcaattttg ccagagtatt acgatgctat cattgaatcg actgaagagt atgggcctta
    28261 ctatatcttg atgccaggta tggctatgcc ccacgctaga cctgaagctg gtgtgcaaag
    28321 tgatgccttt tcattaatta ccttacaaaa tcctgttgta ttttcagatg ggaaagaggt
    28381 atctgttttg ttggcactag cagcaacaag ttcaaaaatt cacacaagtg tagccattcc
    28441 acaaattatt gccctgtttg aattagaaga ttctattgca cgtttacagg cttgccagac
    28501 taaagaagat gtcttggcta tgattgaaga atctaaggat agcccttatc tcgaaggatt
    28561 ggatttggaa agttagaaag aggaataaag aaatgacaaa aagaatacct aatttacaag
    28621 ttgcattaga ccattcagac ttgcaaggag cgattaaagc agctgtttct gttggtcagg
    28681 aagtagatat tatcgaagct ggaactgttt gcttgcttca agttggaagt gaactggctg
    28741 aagtcttgcg tagccttttc ccagataaga ttattgtggc agacacaaaa tgtgctgatg
    28801 ctggtggaac agttgctaaa aataatgcgg ttcgtggagc agactggatg acttgtatct
    28861 gttgtgcaac catccctact atggaagcag ctctaaaggc tatcaagact gaacgaggag
    28921 aacgaggcga aatccagatc gagctttatg gcgattggac ttttgaacaa gctcagcttt
    28981 ggctagatgc aggtatctca caagctattt atcaccaatc tcgtgatgct cttcttgctg
    29041 gtgaaacttg gggtgaaaaa gaccttaata aggttaaaaa actcattgac atgggcttcc
    29101 gtgtatctgt aacaggtggt ctagatgtag atactctcaa actctttgaa ggtgttgatg
    29161 tctttacctt tatcgcaggt cgtggaatta cagaggctgt ggatccagca ggagcagcgc
    29221 gtgccttcaa ggatgaaatc aaacgaattt gggggtaaat catggtacgt ccaattggaa
    29281 tttatgaaaa ggcaacccca acacacttta cttggctaga acgtttaaat tttgccaagg
    29341 agttaggctt tgattttatc gagatgtcta ttgacgaacg tgacgagcgt ttagcaagac
    29401 ttgactggag taaggaagaa cgcttggaag ttgtcaaaga aatctatgaa actggtgttc
    29461 gtattccttc tatctgtttt tcaggccatc gtcgctaccc attgggatca aaagattcag
    29521 ttctagagga aaaatctcta gaactcatga aaaaatgtat cgaattagct caagacttgg
    29581 gagttcgtac gattcaatta gctggttacg atgtttacta tgaggaaaag tcaccccaga
    29641 cacgccaacg ttttatcaaa aatttgagaa aagcctgtga ctgggctgaa gaagctcagg
    29701 tggtacttgc tattgaaatt atggatgatc ctttcatcag tagcatcgaa aaatatttgg
    29761 ctatagaaaa agagattgac tctcccttcc tctttgtata tccagatatt ggtaatgtgt
    29821 ctgcatggca taatgatatc tatagtgagt tttatcttgg tcatcatgcc atcgcagctc
    29881 tccatctcaa ggatacttat gcagtgacag aaagttcaaa gggccagttc cgagatgtac
    29941 ctttcgggca aggttgtgtc aaatgggaag aagctttcga tattttaaag gaaaccaatt
    30001 ataatggacc tttcctaatc gaaatgtggt ctgaaaattg tgaaacagta gaagaaacac
    30061 gcgcagccat tcaagaggcg caagcttttc tctatccact cattaagaaa gcaggtttga
    30121 tgtaagatga atcaagtaat caatgctatg cgtaaacgag tctgtgatgc caatcaatca
    30181 ttgccaaaac atggacttgt caaatttacc tgggggaatg tatctgaagt taatcgcgaa
    30241 ctcggtgtca ttgttatcaa accatcaggc gtggattatg acgaattgac acctgaaaac
    30301 atggtagtga ctgatctaga tggtaagatc ctagaagggg atttaagacc atcttccgac
    30361 ctcccaactc atgtgcaatt atataaggct tggtcagaaa ttggtagtgt ggttcacacc
    30421 cattcgacag aagctgttgg ttgggctcag gcaggtcgtg atattccttt ctacggaaca
    30481 acccatgcag attatttcta cggttcaatc ccttgcgccc gtagtttgac caaggacgaa
    30541 gtagaagtgg cctatgaaaa agatactggc ctggttatcg tagaagagtt tgaacatcgc
    30601 ggacttaacc cggttgaagt accaggaatt attgtacgca atcacggtcc attcacctgg
    30661 ggcaaaaatc cagagaatgc tgtttatcac tctgtcgtac tagaggaagt atcaaagatg
    30721 aatcgcttta cagaacaaat caatccaaga gttggacctg ctccccagta catactagaa
    30781 aaacactacc aacgtaaaca tggaccaaat gcttattatg gtcaaaagta agaacgatga
    30841 aggaggagaa aaagataaat ttagctcctc tttttacatt tgatttttat tgagagtaaa
    30901 gttggaattg aagtaatttt aaaagatttt ttagaaatag cgcttgatat atatatggta
    30961 aaataaaaag aattgctgtg atatcaatag atttggggga ttttttaata tggtactgga
    31021 taaggcaagt tgtgatttgc ttcaatattt gatggatcaa gaaacgtcca aaacgattat
    31081 ggcgatttcg aaagatttga aagagtcaag aaggaaaatt tattatcaca ttgacaaaat
    31141 caatgctgct ctgggtgacg aggcgcttca catcattagt attccacgaa ttggtattca
    31201 cttaacggaa gagcagagag atgcttgttg taaactatta tcggaagtag attcgtacga
    31261 ttatatcatg agtgcgcatg aacgtatgat gataatgtta ctatggatag gtatttctaa
    31321 agaacgtatt acgattgaaa aattgataga gttaacagag gtatctagga atactgttct
    31381 caatgatttg aatagtattc gttatcaact aactttggaa caatatcagg tgatcttgca
    31441 agtgagcaag tcacagggat accaccttca tgcccaccct cttaataaaa ttcagtatct
    31501 tcaatcgctt ctatatcata tttttatgga agaaaatgcc acttttgtat ctattttaga
    31561 agataagatg aaagagaggt tagatgatga gtgtttgctt tctgttgaaa tgaaccaatt
    31621 ttttaaggaa caggttcctt tagttgaaca agatttaggg aagaaaataa accatcatga
    31681 aataactttt atgttgcagg ttctacctta tttgctgtta agctgtcata atgttgaaca
    31741 gtatcaagaa agacatcagg atatagagaa agaattttct ttgataagaa aaagaataga
    31801 gtatcaggtg tctaagaaat taggagaacg gttgtttcaa aagtttgaaa tttctttgtc
    31861 aggacttgaa gtttctcttg tagctgttct cctcctctcc tatcgtaaag atttggatat
    31921 tcatgcagaa agtgatgatt ttcggcaatt aaaacttgct ttagaagaat ttatctggta
    31981 ttttgaatca caaatccgaa tggagattga gaacaaggat gatttgttac gaaatttgat
    32041 gatccactgt aaagccttgt tatttagaaa gacttacggt attttttcta aaaatcctct
    32101 aacaaaacaa attcgatcca agtatggaga attattttta gtcactagaa aatctgcgga
    32161 aattttagaa ggagcatggt ttattcggct aacagacgat gatattgcct atttgacgat
    32221 tcatattgga ggatttttaa aatatacacc atcgtctcaa aaaaatatga aaaaagttta
    32281 tctcgtttgt gatgaaggtg ttgcggtttc gagacttttg ctgaaacaat gcaaacttta
    32341 ttttccaaat gagcaaattg acactgtatt tacaacagaa caatttaaga gtgtggaaga
    32401 tattgcacaa gttgatgtag tgattactac taatgatgat ttggatagca gatttccgat
    32461 tttaagggtt aatcctatcc ttgaagcaga agatattttg aaaatgctag actatcttaa
    32521 acacaatata tttcgtaata agagcaaaag tttcagtgaa aatctttcta gtcttatttc
    32581 gtcttatatt gtagacagca agttggctag taagttccaa gaagaggttc aaacacttat
    32641 aaatcaagaa atagtagttc aagctttttt ggaagatatt tgaaggacag tccaatgatg
    32701 aacacaaacc tgtgtttttc ttggtctttt ttagtgtttt gaagggtggt atactaatct
    32761 caaagataac aattatatcc aaaggaggca acatatgcca aacgtcaaag aaattacaag
    32821 agagtcatgg attttagcca ctttcccaga gtggggaaca tggttgaacg aagaaatcga
    32881 agaagaagtc gtacctgaag gcaactttgc catgtggtgg ctaggcaact gtggtacttg
    32941 gattaagaca ccagctggtg ctaacgttgt catggacctt tggtcaaacc gtggaaaatc
    33001 aaccaaaaaa gtgaaagata tggttcgtgg gcaccaaatg gcaaatatgg caggtgttcg
    33061 taagttgcaa ccaaacttgc gtgttcagcc aatggttatc gatccatttg ctatcaacga
    33121 actagactat tacttagttt cacacttcca cagtgatcat atcgacccat acacagctgc
    33181 agcaattctc aacaatccta agttagagca tgttaagttt atcggtcctt accactgtgg
    33241 acgaatctgg gaaggatggg gtgttccaaa agaacgtatc atcgttgtta aaccaggtga
    33301 cactatcgaa ttaaaagata tgaagattca tgcagtagaa tcatttgacc gtacttgctt
    33361 ggtaactctc ccagtgaacg gtgctgatga gacaggcggt gaacttgctg gcttggctgt
    33421 tacagatgaa gaaatggctc aaaaggctgt taactatatc tttgaaacac caggtggaac
    33481 catctatcat ggtgcagatt ctcacttctc aaactatttt gcaaaacatg gtaaagactt
    33541 taaaattgat gttgctttga ataactatgg tgaaaatccg gtaggtatcc aagacaaaat
    33601 gacatctatc gaccttcttc gtatggcaga aaatctgcgt accaaagtca ttatcccagt
    33661 tcactatgat atctggtcta acttcatggc ttctactaat gagattctag aactttggaa
    33721 aatgcgaaaa gatcgcttgc aatacgattt ccatccattt atctgggaag ttggcggtaa
    33781 gtacacttat cctcaagatc aacacttagt agaataccat catccacgtg gttttgatga
    33841 ttgttttgaa caagactcta acattcaatt taaagctttg ctataatata aaaatattct
    33901 ttggaggtta tccgtatgtt gcatgatacg gataattttc atataatagt aaaatagaat
    33961 gtgtgattca ataatcacct caaatagaaa ggaaattcta tgtcaaatct atctgttaat
    34021 gcaattcgtt ttctaggtat tgacgccatt aataaagcca actcaggtca tccaggtgtg
    34081 gttatgggag cggctccgat ggcttacagc ctctttacaa aacaacttca tatcaatcca
    34141 gctcaaccaa actggattaa ccgcgaccgc tttattcttt cagcaggtca tggttcaatg
    34201 ctcctttatg ctcttcttca cctttctggt tttgaagatg tcagcatgga tgagattaag
    34261 agtttccgtc aatggggttc aaaaacacca ggtcacccag aatttggtca tacggcaggg
    34321 attgatgcta cgacaggtcc tctagggcaa ggtatttcaa ctgctactgg ttttgcccaa
    34381 gcagaacgtt tcttggcagc caaatataac cgtgaaggct acaatatctt tgaccactat
    34441 acttacgtta tctgtggaga cggagacttg atggaaggtg tctcaagcga ggcagcttca
    34501 tacgcaggtt tgcaaaaact tgataagttg gttgttcttt atgattcaaa tgatatcaac
    34561 ttggatggtg agacaaagga ttcctttaca gaaagtgttc gtgaccgtta caatgcctac
    34621 ggttggcata ctgccttggt tgaaaatgga acagacttgg aagccatcca tgctgctatc
    34681 gaaacagcaa aagcttcagg caagccatct ttgattgaag tgaagacggt tattggatac
    34741 ggttctccaa acaaacaagg aactaatgct gtacacggcg cccctcttgg agcagatgaa
    34801 actgcatcaa ctcgtcaagc cctcggttgg gactacgaac catttgaaat tccagaacaa
    34861 gtatatgctg atttcaaaga acatgttgca gaccgtggcg catcagctta tcaagcttgg
    34921 actaaattag ttgcagatta taaagaagct catccagaac tggctgcaga agtagaagcc
    34981 atcatcgacg gacgtgatcc agtcgaagtg actccagcag acttcccagc tttagaaaat
    35041 ggtttttctc aagcaactcg taattcaagt caagatgcct tgaatgttgt ggcagctaaa
    35101 ttaccaacct ttctaggtgg atcagctgac cttgctcact caaacatgac ttatatcaag
    35161 acggatggac ttcaagacga tgccaatcgc ttgaatcgta acattcagtt tggtgttcgt
    35221 gaatttgcaa tgggaacaat cttgaacggg atggcccttc atggtggact tcgtgtatac
    35281 ggtggaactt tcttcgtctt ctctgactat gtgaaggcag ctgtccgctt gtcagcctta
    35341 caaggacttc ctgtgactta tgtctttacc catgattcaa tcgcagttgg ggaagatggt
    35401 ccgactcacg aaccagttga gcatttagca ggtcttcgtg ctatgccaaa tctaaatgtt
    35461 ttccgtccag cagatgcgcg tgaaacgcaa gcagcttggt accttgcagt gacaagtgag
    35521 aaaacaccaa ctgcccttgt cttgacacgt caaaacttga ctgttgaaga tggaacagac
    35581 ttcgacaagg ttgctaaagg tgcttatgtt gtatatgaaa atgcagccga ctttgatacc
    35641 atcttgattg cgacaggttc agaggttaat cttgctgtct cagctgctaa agaattggct
    35701 agtcaaggcg aaaaaatccg cgtagtcagc atgccatcta cagatgtctt tgataaacaa
    35761 gatgcagctt acaaggaaga aattcttcca aatgcagtcc gccgtcgtgt tgcagtcgaa
    35821 atgggtgcaa gtcaaaactg gtacaaatat gttggtctcg atggtgccgt tctaggtatt
    35881 gataccttcg gagcctctgc cccagcacca aaagtattgg cagaatatgg ctttactgta
    35941 gaaaatcttg taaaaattgt tcgaaacttg aaataatcct aaaaatcagg gcgtaagctc
    36001 tggtttttct taccagaaaa gtaaggtaca atcttgtaaa agtagctgaa atttgatata
    36061 gtagtcctat gtaaaagaca aaggagaaaa caatgaatcc aaatattact tttttaatca
    36121 tgcttgtagg tatgatggcc ttgatgttct ttatgcaacg ttctcaaaag aaacaagctc
    36181 aaaagcgtat ggaaagctta aataaactac aaaaaggcta tgaagtgatt acaatcggtg
    36241 gactttatgg aacagtcgat gaagtagata cggagaaggg aacaatagtt cttgacgtag
    36301 atggagttta cttgactttt gaactagctg ctatcaagac agtattaccg ctgaaagaaa
    36361 cagcttcact agaaggcgca attgaaaaat aagacgggat cacgaactcc cgtttttcta
    36421 taaaagaaag gaaatgggat gaaaaaatta gtctttgtct gtctgggaaa tatttgccgt
    36481 agccctatgg ccgagtttgt tatgaaatca atgacagata actacgaaat ccaaagtcga
    36541 gcaacttcct cttgggaaca tggcaatccg attcataagg ggactcaggg aatttttcaa
    36601 cagtatgaga ttctttatga caagaacaag acatcgcttc agattagtaa ggaagatttt
    36661 gaagcctttg attatattat cggaatggac gcttcaaata tttctgactt acgtcagatg
    36721 tgtccagtag actgtcaaga taagatttac tcattttcat ctgaaagtgt tccagaccct
    36781 tggtatacag gagattttga agaaacctat cgacgtgttc aagagggctg tcaagcttgg
    36841 ttagaacgtt tagaaaagga gagttaaggt ggaaaatctt acgaattttt acgaaaagta
    36901 tcgtgtctat ctgactcgtc cacgtttaga gcttttggca gtagttacca ttgttttctg
    36961 tgctgtactc gtcttttttc taaatattcc aggaaaaggt gtcttaaaac tcgataatgg
    37021 aacgattgtt tatgatggca gtcttgtccg tggtaaaatg aatggtcaag gtaccattac
    37081 cttccaaaat ggagaccaat atacaggtgg cttcaacaat ggagccttca acggaaaagg
    37141 tacctttcaa tctaaagaag gctggaccta cgaaggtgat tttgtaaatg gtcaggctga
    37201 aggaaaaggg aaactaacaa cagaacaaga agtcgtttat gaaggaactt ttaaacaagg
    37261 cgtttttcaa caaaaataaa gcctccttat ccaaaggagg tattattaga accacaaggt
    37321 aagcgcttac ctgtaaatcc ctttctttcc aaatccctct tccaagcaag tttgtgaaat
    37381 aaaaaatatt tgaaataaat ttcacaaact tcaaagataa aacctgataa gaaaagaaaa
    37441 tgagaaaagt ttcacaagag tttaaaaatt ctttgtgaaa tgtttatgaa actgtttaca
    37501 aagttgaaat aatgcgttat aataaacttg tgaaaaaatt aacaaaggat atcgttcctt
    37561 gaaagctatg gaggaaaata tggctgataa aaaaactgtg acaccagagg aaaagaaact
    37621 cgttgctgaa aaacacgtag atgagttggt tcaaaaagct ctagttgccc ttgaagaaat
    37681 gcgtaaattg gatcaagagc aagttgacta catcgttgct aaagcatcag tagcagcttt
    37741 ggatgcccac ggagaattgg ctttacatgc ctttgaagaa acaggacgtg gtgtatttga
    37801 agataaagca actaagaact tgtttgcctg tgaacacgta gtaaacaaca tgcgtcacac
    37861 taagacagtt ggcgttatcg aagaagacga tgtaacagga ttgactctta ttgctgaacc
    37921 agttggtgtt gtttgtggta ttactccaac aacaaaccca acatcaacag caatcttcaa
    37981 atcattgatt tcattgaaga cacgtaaccc aatcgtcttt gccttccatc catcagcaca
    38041 agaatcatct gctcatgcag ctcgtatcgt ccgcgatgca gctatcgcag ctggtgctcc
    38101 tgaaaactgt gtgcaatgga ttactcaacc atctatggaa gcaacaagtg cccttatgaa
    38161 ccacgaaggt gttgcgacaa tccttgcaac aggtggtaat gccatggtta aggcggctta
    38221 ttcatgtggt aaaccagctc ttggggtagg tgccggaaac gttccagctt atgttgaaaa
    38281 atcagcaaac attcgtcaag cagcacacga tatcgtcatg tctaaatcat ttgataacgg
    38341 tatggtctgt gcatctgaac aagcagttat cattgataaa gaaatttacg atgaatttgt
    38401 agcagagttc aaatcttacc acacttactt tgtaaacaaa aaagaaaaag ctcttcttga
    38461 agagttctgc ttcggcgtca aagcaaacag caaaaactgt gctggtgcaa aattgaacgc
    38521 tgacatcgtt ggtaaaccag caacttggat tgcagaacaa gcaggattta cagttccaga
    38581 aggaacaaac attcttgctg cagaatgtaa agaagttggc gaaaatgagc cattgactcg
    38641 tgaaaaattg tcaccagtta ttgcagtttt gaaatctgaa agccgtgaag atggtattac
    38701 taaggctcgt caaatggttg aatttaacgg tcttggacac tcagcagcta tccacacagc
    38761 tgacgaagaa ttgactaaag aatttggtaa agctgttaaa gctattcgtg ttatctgtaa
    38821 ctcaccttct acttttggtg gtattgggga cgtttacaat gccttcttgc catcattgac
    38881 acttggatgt ggttcttacg gacgcaactc agttggggat aacgttagtg ccattaacct
    38941 cttgaatatc aaaaaagtcg gaagacggag aaataacatg caatggatga aacttccttc
    39001 aaaaacatac tttgaacgtg attcaattca ataccttcaa aaatgtcgtg acgttgaacg
    39061 tgtcatgatc gttactgacc atgccatggt agagcttggt ttccttgatc gtatcatcga
    39121 acaactggac cttcgtcgca ataaggttgt ttaccaaatc tttgcggatg tagaaccgga
    39181 tccagatatc acaactgtaa accgtggtac tgagattatg cgtgccttca aaccagatac
    39241 catcatcgca ctcggtggtg ggtctccaat ggatgctgcc aaagtaatgt ggctcttcta
    39301 cgagcaacca gaagtggact tccgtgacct tgtccaaaaa ttcatggata tccgtaaacg
    39361 tgccttcaag ttcccattgc ttggtaagaa gactaaattc atcgcgattc caactacatc
    39421 tggtacagga tctgaagtaa caccatttgc cgttatctct gataaagcaa acaaccgtaa
    39481 atacccaatc gctgactact cattgacacc aactgtggca atcgtagatc ctgctttggt
    39541 attgacagtt ccaggatttg ttgctgctga tactggtatg gacgtattga ctcacgcgac
    39601 agaagcatac gtatcacaaa tggctagtga ctacactgat ggtttagcac ttcaagccat
    39661 taaattggtc tttgaaaatc tcgaaagctc agttaagaat gcagacttcc actcacgtga
    39721 gaaaatgcat aacgcttcaa caatcgctgg tatggccttt gccaatgcct tcctaggtat
    39781 ttctcactca atggcccata agattggtgc gcaattccac acaatccacg gtcgtacaaa
    39841 tgccatcttg cttccatacg ttatccgtta caacggtaca cgtccagcta agacagcaac
    39901 atggcctaag tacaactact accgtgcaga tgaaaaatac caagatatcg cacgcatgct
    39961 tggacttcca gcttctactc cagaagaagg ggttgaatct tacgcaaaag ctgtctacga
    40021 actcggtgaa cgtattggga tccaaatgaa ttttagagac caaggaattg acgaaaaaga
    40081 atggaaagaa cattctcgtg aattagcctt cctggcttat gaagaccaat gttcaccagc
    40141 taacccacgt cttccaatgg tagaccatat gcaagaaatc atcgaagatg catactatgg
    40201 ctacaaagaa agaccaggac gccgtaaata attgtttatc agtctagaag caagacaaaa
    40261 actcaatttg agggaaagat ccagtaattt ttctatgata aaaggcatcc tatcaaggtt
    40321 tttgaacacc tgataggatg cctttttatg atattgaggc ctttttgccc tttttgaaaa
    40381 actagaatag aaacaaaata tataatagat tgaaactaga atagtacaca tctgcttcta
    40441 aaacattgtt agaattcgat ttgactgtcc tgatcgattt gtcctgttct tatttcattt
    40501 tgatatataa aaaatatagt atagtagact gaatctaaaa tagtacgaaa caattgctaa
    40561 aacatttata gaaattaatt ttactttcct gatagagttg ttcacatctt atttcaattc
    40621 actatagttt aatttaagag tagtatttac taaggcccaa ttaaaatcaa agagcaaacg
    40681 agaaaacgat gacaaggtgt gttgcttttt gatttctaaa gagtataatg atagatctct
    40741 ataaaataag tgcgaaggaa atgagctttt ataatccttt cgttttaaaa tactatctca
    40801 gatattctta tatcgacaag aagtttttga gtcattccct catcatacat attaaataaa
    40861 tagtggctca ttcaattttt cactagaata ataagctagt atagtaaact gaaataagat
    40921 ataaacaaat aaattggagc ttaacatcca tttccagcaa ttttttagaa actacagtgg
    40981 actattctag attcaacata ttataaaaac tagagtaaaa gaaaaggatt ggatcttgtg
    41041 taatgcagga tccaatcctt tcaatcattt tgtccaactt ttggaggttc ctacaatgta
    41101 gccgtcatta ataaagacag atgggaacga cagtgttcct atttattttg atagagatcg
    41161 atgaattctt tagatagcaa ctgaataatc tccgttgaag ccatttggtc ttctgcatgc
    41221 ataaatagca aggagaatcc tattttttct ccagtagctt ctttttgtat gagattagag
    41281 tgaatcttgt gcacttctac taaggagtct tccgcttctt caactttaat tttcgcttct
    41341 tttaaatttc ctgccttagc tagttggatg gcttcaataa aggatgattt ggctgctcca
    41401 ctattggcaa tgagctgaaa acagatatat tccatttctt ctgtcatctt atttctccta
    41461 tccatgcaag tgcttgttcc agaacttttg ctccattcat cattccgtaa tcccgcatat
    41521 caatggtatc tacagggata tttcctgcaa tttctttcac agcaagtaac tcataacgaa
    41581 tttgtggccc aattagaatg acatctgctt catggatatt ctttttcgcc tctgtcattg
    41641 attttgcttg gatagaaatt tcaatcccac gttcagtcgc actttgttgc atttttttaa
    41701 caagcatact tgtcgacatt cccgcattac atactaataa aatttgtttc ataatcttaa
    41761 ccttccattt cttgttcaac aactttgtca ttaactttga taaatggaat gtatagaaga
    41821 actccaagtg caaagatgat gaattgaact agaactgctc tcacgtcccc tgctgttgct
    41881 aaccatgcat ttaagaatac tggtgtagtc caaggaactt gtataaatgc aggactcatg
    41941 aatcctgtaa ctgttgctaa gtagctgatt aaaataccaa ggactggaac tgtgataaat
    42001 ggaatagcta atgaaatgtt ataaacgatt gggtaaccga ataatactgg ttcattgata
    42061 ttgaagatac caggtccaaa agataattta gccacgtttt tagagacagc attgcgactc
    42121 actaagaatg ttgctattaa taaacataat gtagatccac taccacccat taaagcgaat
    42181 gtttgtattt gtgataggtt gatgatgtgt ggaatggctt gtccattatt tgctgcagtg
    42241 atgttttcag taatgttaat taatagtaat ggttctagga tggcactgta aataactgct
    42301 tggtgaatac caaatagcca taacatattt cctaaagagt aaataataat gaccccgatt
    42361 aagcttgtac caatatgacg aattggttct tgaataaaga ttgtaatgat tgagattaag
    42421 ttcattccag ttatattgaa taataatgct gaaacaactc caaataagga gatgacggtc
    42481 atgactggaa gtaatacgct aaatgatcta ctaacagctg gtggaatatt ttcaccaagg
    42541 ttcatttgta aagctttaac gtttgataat tcaatgaata attctgttgc aataatcgct
    42601 acgataaccc cggcgaacat tgcgcctgta cctgtgttgt tgaatgaaag aacacctgaa
    42661 atgtttaccg catcttttgc tccgtcagga actacagaaa ctgtatttgg catcatcaca
    42721 attaaagaaa ctaatgatag cattgatgct gctaacgggt tttcgaaatc tctgttttta
    42781 gctaagaaat aaccaaccat tacagcaata atcatacctg aaatacttaa agtaccgttt
    42841 gcaattgtta ttccccaata ttggaatctt gttaatgtat ccccttggaa aatccactta
    42901 aataccgtgt tgttcaaaag aacgattaaa cctgccaaaa tatataatgg cattactgtt
    42961 acgaatgcat ctcttagggt ttttaaatga atttggttcc ctagtttacc agcaaaggtg
    43021 gcaaattggt ctataaattt tgagtttttc atatgaatat ctcctctctt tactcctcaa
    43081 tttctacttc aaaaccgtta ttgtcactta ctttgcgata ccatcttcct gagctcttga
    43141 tggttctctt ttgcgtttct aaatcaacgg agataaatcc gtaacgattc ttatatgcat
    43201 tattccaaga ccagcaatca aatgcggtcc aagcgtggta tccaaaacag tgacttccct
    43261 cttcaatggc tttatgtagc catcttaaat gttcttcata aaattcaata cgatacacgt
    43321 catcgataac tccattttca tcgataaacc gtgcttcgtt ttcaacaccc attccgtttt
    43381 cactgataaa ccatgggata ttaccatatt cttccttcac aatcatagca atatcataaa
    43441 tggctttcgg aaaaatttcc caaccacgat atggattcat gcgacgctcc agccattcat
    43501 actctttgaa gtattggtct ggcatccagg gcgtctgata ttcttcagga tttgcttgtg
    43561 cttgaacacg ttttggatgg tagtagttta ctccaagaaa atcaaccgta tttgatttca
    43621 tcagttgaag ctctttttcg gtatgactcc ataacacgcc atctctctct agctgtttta
    43681 ccaatctttc tgggaaagtt cctttaacag ctggattcaa gaagactttg ttaaagaagt
    43741 catctgtaaa tcgacttgct tctaagtctt ctggagaatt acttcttgga taagcaggtg
    43801 tcaagtttaa aataatccca atctttccat caagttctaa tgagcgatat agttgaatca
    43861 cttttgcact agcaaggttt agattataga tgacttgtac ggcctctttt ccctttcctt
    43921 ttagatttgg ataatggaaa gcatataagt atcctgcttc tggaatgacc attggctcat
    43981 tgaaagttgt ccagtaatga accttatctc caaagcatgt gaaagcagtc ttggcaaact
    44041 tcacgaataa ctccactaca tgtttgcttt cccaaccacc gtatttttga agaagttcca
    44101 ctggtaaatc aaaatgatgt aaattcatca caagatccat ctggttcttt ttagcttctt
    44161 caatgatggc attgtagaaa gcaatacctt ttggatcagg ctcacctgtc tctaaattct
    44221 tgatgagtcg actccattgg atggaagtgc ggaaagaatt aactccaatt tccttcatca
    44281 agtggaaatc ttcggtgtaa gtatgaaaaa agttactggc tacaagaggt ccgacattat
    44341 cgaaaaaatc ttctggatgc gttttgaacc agtagtccat cacattttca tgtacttttc
    44401 catattgacc ttctgtctga ggtccgctag aagcagctcc ccaccaaaat agattaggaa
    44461 atactaactt ttttttcatg ctcaacctcc tttctattat tctatacata aagtatagca
    44521 taattttaaa atttgtctag acatttttaa aaattgttga tacatatctt gtgtttgcct
    44581 catttcttga actttgttat actactatta gaatattata gagagaacca gattaaatga
    44641 gtacaaaata tttatttatt tacaatgaga ttcgtgaaaa gattctttgt aataaatata
    44701 ccatgaacga acaattgcct gatgaaatga cattagctaa acagtttgcc tgtagtcgaa
    44761 tgacgatcaa aaaagcttta gacttgttag tttctgaggg cttaattttt agaaaacgtg
    44821 ggcagggaac ctttgttctc tctcgtggca gctcaaaaag aaaattaatc gttccagaaa
    44881 gagatatccg gggactgaca aaaatatctg aagatgctca ttctacaatt gactcgagga
    44941 ttattcactt caaattagaa tttgcaaatg aatttttagc agaaaaacta caggtcgctt
    45001 tgcagagtcc agtttataat atttaccgtc tgcgtattat tgacggtaaa ccttatgttc
    45061 tggaacaaac ttatatgagt actgatgtta ttccaggtat tactgaagat attttacaaa
    45121 aatcgattta caattacatt gaaggaaagt taggattgca tattgccagt gctacaaaaa
    45181 tcttgcgagc ttcttctagt tcagaaaatg agcaacatta cttgcagctc cttccaacgg
    45241 aaccggtatt tgaagtagaa caagtggctt atttggataa cggaactccg tttgagtact
    45301 cgattagtcg tcatcgctat gatttatttg aatttaattc ttttgcatta cgacattcct
    45361 cctaggagaa aatgtgaaaa tgaagccaat cttttacaga ctctagttta agaaaaattt
    45421 aaaacagggc aagaaggtcc catctatgct taaatggttt ctcttttcta aataagatgg
    45481 ctttaaaaga gtgatcgttt tatccatcat gttgaaaaat atcttcgtat agcttataga
    45541 gtaggtactg aaattgttca cctgatctac ttcttatagt tatttagttt taaatagtgt
    45601 ttcaaatatt cttacactga cgagaagttt ttgagtcttt tcttgtaaca catatagtat
    45661 actgatgtta gaatagtaga ctgtgacttc taacaaattg ctagaaatga atttcaatct
    45721 cccaatttat ttgttcatat cttcttttaa tatattaaat aaattctgaa tcataatcat
    45781 ttaaaaaaat tttatttttt atttttcatt acgaataata tagatgaagg ggaaagagta
    45841 tgaaaacaga acggtttctt ttgctattag ttcaaaagga gaaaaaatga aagtagaaaa
    45901 tatttcgtat agggtggatc atcgtatatt gtttgataat atttcttttg atacttcgag
    45961 ttcaggcgtg acattaatta ctggtaaaaa tggtacagga aagtcaactt tactatagta
    46021 gattgaaact agaatagtac acatctactt ctaaaatatt gttagaaatc gatttgacta
    46081 tcctgatcta tttgtcctgt tcttatttca tttcactaca tctcaaattg agtatgacga
    46141 agtgcgctcc catgtcctgg gaacgcactt tcttcatatt tttcatattc ttgaatccat
    46201 cgataaagac tattgggatg aatttttaaa gttgaactaa ttatttttac aggatgaggt
    46261 ttacagcaga gagtttgaag gctttatcaa aggtttttct tggcataatg acttttcctc
    46321 gtttccactt aattttgtgt ctactttatt ataccaagtc cacccttaag ttagataatg
    46381 aatctaactt aaggaagcta gaaggatgag aatccaggtg gtcaagagtc ccaaacttaa
    46441 gctgataggg acacccagaa taatttgctt tttgaaggca agaccgcgtt cctctatatt
    46501 gggaagtgag agttgaatga gagaaccagc tgatgaaaag ggtgagatat tagtagatag
    46561 agcgccaata acggtggctg ttgtgagtaa gtgaatatca atctgaggat tttgagcact
    46621 gatgatagca atgatgggaa agagggctgg agctacaacg gatagggtgg aactaaagag
    46681 tgacatcact ccggctatca cacaaaagaa cagaggtaac cagaaatgag gaatggttgt
    46741 tgtcatgagg tgccctatca gtgtgactaa acctgacttg accgctagag acattagtaa
    46801 gctcatgccg cagagcatga taattgtagc ccagggaacc ttagctaaaa tggcttcttg
    46861 cttccctaat ttgagcttta aggcgaggca gaccatgagt attgagacaa agccaatatc
    46921 aaatgttttt tgataagtag ctatccaggc gatgtttggg aaaatgagat gcaacaaggg
    46981 aaaaagccaa accaaaacca tgctgctgat catgagcaag gtggtttgtc tttgaacctt
    47041 gctgaggagt ggtggttggt caatagtcaa ggatgagttt gttcttccct tactatagtg
    47101 actgtaacag gataataaaa gcaagacgat gagtgggtag ataatgctga cgataaagat
    47161 atgattgcca agtgaaaaag cttgctcttc ccatcccatt tgcttaaaca ggccttgaaa
    47221 gacaatgcct gagctactgg ttatcaaatt agcccctcct gaagctcccc aattgacggc
    47281 ttgagctcca atcaaagggt gtttgtccgc tttttgacag agggtaatcg ctagaggaca
    47341 gcaaacggcc atagtagtga aaaatccagc acctaaagca gacaaaaggg ttgccatcag
    47401 gtataaaatc atgtagaggg cgttagggtg ggtgcgtgtg cggtagagaa tgtgttgagc
    47461 caaaacatca agagtaccgt tagttgttgc aacgttataa aagagagaga cgctaaaaat
    47521 ggtaaaaaag agtgaggttg gccaaaaatg aagaagttct ttggggctta atcccatgag
    47581 agtggttgcg atgaggtaag aaaaagcaat agccagcagg ccaatattga ttttggtgcg
    47641 gtaaccaatt ccaatggcta gagcaatggc gctaatcatt attaaatgaa tcattgaatt
    47701 gtcctttcag ttagaatatg gaaataggtt ggcaattttg gcgctcaaaa gaccacctgt
    47761 ttcctattgg tacttgacta ttatacacaa aaaaaataca attgtcttga caattgtatt
    47821 gacacttgtt agaattaaaa atgaggtatt caggcttgtg atttcctatg gaagttaata
    47881 gtaattgcct ctagtgctta caagtgatat taaaaataga ggacttagtg atgtcaatca
    47941 tttcaactga tttaacccct tttcaaatag atgatacatt gaaagcagcc ttgcgagaag
    48001 atgttcattc cgaagattac agtaccaatg ccatttttga tcatcatggc caagctaagg
    48061 tgtcgctttt tgccaaggaa gctggtgttt tagcggggct aaccgttttt caaagggttt
    48121 ttaccctatt tgatgccgag gtgaccttcc agaatcctca tcaatttaag gatggggatc
    48181 gtttgactag tggcgatttg gttttagaaa tcataggctc ggtgagaagt ctcttaacat
    48241 gtgaacgcgt tgccttgaat tttttacaac atttatcagg gattgcttcg atgacagctg
    48301 cttatgtaga agccttaggc gatgattgca ttaaggtatt tgatactcga aaaactactc
    48361 ctaatttacg tctttttgag aaatatgccg tgagagttgg cggtggctat aatcatcgct
    48421 ttaatttatc agatgctatc atgctaaaag acaatcacat tgcggcagta ggtagtgttc
    48481 aaaaggcaat tgctcaagcg cgtgcctatg ccccttttgt gaaaatggtc gaggtggaag
    48541 tggaaagcct tgctgctgcc gaagaagctg cggcggcggg tgctgatatt atcatgttgg
    48601 ataatatgtc attggaacag attgaacagg ccattaccct aattgcagga cgttctcgga
    48661 ttgaatgttc tggaaatatt gatatgacca ctattagccg ttttcgtggt ttagcgattg
    48721 attacgtctc cagtggtagt ttaacccata gtgctaagag tcttgatttt tccatgaagg
    48781 ggttaaccta ccttgatgtc taagttgtaa aataaactaa ctttttaaag gatgtctttc
    48841 ctctagaacg agttttatgt cagatagttt aaacgcctct tcaaatatag taaaatgaac
    48901 caaaaatagt acacaatgtg gtataatctt tttatggcat attcaataga ttttcgtaaa
    48961 aaagttctct cttattgtga gcgaacaggt agtataacag aagcatcaca cgttttccaa
    49021 atctcacgta ataccattta tggctggtta aagctaaaag agaaaacagg agagctaaac
    49081 caccaagtaa aaggaacaaa accaagaaag gttgatagag atagacttaa aaactatctt
    49141 actgacaatc cagacgctta tttgactgaa atagcttctg aatttggctg tcatccaact
    49201 accatccact atgcactcaa agctatgggc tacactcgaa aaaaagaacc acacctacta
    49261 tgaacaagac ccagaaaaag tagccttatt tcttaagaat tttaatagtt taaagcacct
    49321 atcacctgtt tagattgatg aaacaggatt tgatacttat ttttatcgag aatatggtcg
    49381 ctctttaaaa ggtcagttaa gaagaagata tcagaggatt tctttggttg caggtctaac
    49441 aaatgaatgg tgagttaatc gctccaatga cttacgaaga gacgatgacg agcgactttt
    49501 ttgaagcatg gtttcagaag tttctcttac caacattaac cacaccatcg gttattatta
    49561 tggataatgc aagattccat agaatgggta agttagaact cttgtgtgaa gagtttgggc
    49621 ataaactttt acctcttcct ccctactcac ctgagtacaa tctattgaga aaacatgggc
    49681 tcatatcaaa aagcacctca aaaaggtatt accaagttgc aatacctttt acgaggcttt
    49741 tttatcctgc tcttgtttca attgactata gttcacggat acagttggga aagaagctat
    49801 taaatatttg gagagtcctt ttgggatgaa catgtcaaat attactatag atgggcaaga
    49861 aaagatgggc aagaaatgga tctgagtcaa acgatgcctt cttatgctca agtagtgagt
    49921 ctttatgatg atacaagtat ctctgttagt aataatgaga cggacaaagt gttggctggc
    49981 tccctctata ctgatacaaa tgaacaggga ttaacgattc caagcagttt actaaaaaat
    50041 tggaatgaac agacaggaaa aaatttgaca gctaatgatc ttattggcaa atcagtctca
    50101 gccagcattg tagaaagtgc tgccgaaact agtaagattg ctcaatttca aacgaagatt
    50161 gtacgtgtaa tcaatgatga agatgacatg gaggacagca acagtttcat gctgtctcat
    50221 caaatggaaa cgattttgaa agaggctgga tttacgaaag ctgtatctta ttttatcttg
    50281 gaactcaaag atccatcaca gacaaaagta gtaacagaag aattacagaa aaataagaag
    50341 tatactgtgc tttctcaaca gagagttctt gatattgtga ttacctttat tcgtgttatt
    50401 cagggattat tgattgtgct ttcatcacaa gctattgtgg tagcagcggt tatgattggt
    50461 atcattattt acatcaatat catgcaacgt tccaaggaaa taggtgtcat gaaagcagtt
    50521 ggttatcaga atcgtggtgt caaaggaatt tttatttacg aggctatctg gattgtaggc
    50581 atcgccttgc tgctggcatt tttggttgca caaggggtgg gaagtttggc gaatgcgatt
    50641 gtaagtcact tttacccatc catcactaag gtttttgaat taaatctttt atctgtttta
    50701 ggaactctag ttttcgctct attacttggt tatgtctcag cctacttccc ggcgcgtaag
    50761 attagtaaaa tggatcctgt agaatcgtta cgctatgaat aataagggat tccttgattt
    50821 acagtcttaa aaagaaactc acatagaaaa acaatggcca tacttgcaat tcaactcaaa
    50881 tagttgtata ataggtttgt tgaaaggtga tttgtagtga ttcaagttac tcttttcaca
    50941 ataaaaattt catgattttc ataaggagga aatcactaat ggtagttaaa gttggtatta
    51001 acggtttcgg acgtatcggt cgtcttgctt tccgtcgtat ccaaaacgta gaaggtgttg
    51061 aagttacacg catcaacgac cttacagatc cagttatgct tgcacacttg ttgaaatacg
    51121 acacaactca aggtcgtttc gacggtactg ttgaagttaa agaaggtgga ttcgaagtta
    51181 acggtaaatt cgttaaagtt tctgctgaac gtgatccaga gcaaatcgac tgggctactg
    51241 acggtgtaga aatcgttctt gaagctactg gtttctttgc taagaaagaa gcagctgaaa
    51301 aacaccttaa aggtggagct aaaaaagttg ttatcactgc tcctggtgga aacgacgtta
    51361 aaacagttgt attcaacact aaccacgacg ttcttgacgg tactgaaaca gttatctcag
    51421 gtgcttcatg tactacaaac tgcttggctc caatggctaa agctcttcaa gataactttg
    51481 gtgttgttga aggattgatg actactatcc acgcttacac tggtgaccaa atgatccttg
    51541 acggaccaca ccgtggtggt gaccttcgcc gtgctcgcgc tggtgctgca aacatcgttc
    51601 ctaactcaac tggtgctgct aaagctatcg gtcttgtaat cccagaattg aacggtaaac
    51661 ttgacggatc tgcacaacgc gttccaactc caactggatc agttactgaa ttggtagcag
    51721 ttcttgaaaa gaacgttact gttgatgaag tgaacgcagc tatgaaagca gcttcaaacg
    51781 aatcatacgg ttacacagaa gatccaatcg tatcttcaga tatcgtaggt atgtcttacg
    51841 gttcattgtt tgacgcaact caaactaaag ttcttgacgt tgacggtaaa caattggtta
    51901 aagttgtatc atggtacgac aacgaaatgt catacactgc acaacttgtt cgtactcttg
    51961 aatacttcgc aaaaattgct aaataattct tgagttgata gaaagcaagg ctttgtggtc
    52021 ttgcttttta tatggaaaaa tggatgacac gatcatccat tcttttttaa ttctttttca
    52081 aatgtatttg aaagggtagt gaaagttagc ttctctaaag taagtgggtg ggtaaaggaa
    52141 agtcggaagg catgaagcat aagccggctt gtctttgatt tactattata gagagggtct
    52201 cccaggatag gaagattatg atgcgaaagg tgcacacgaa tctgatgggt tcgccctgtc
    52261 tttagcttgc aatgagccaa ggaagtcttg tttgagaatt gctttaatct gcttacatgc
    52321 gtttcagcat attgcccatt ttttgcatca actattcttt ttctacgatc atggcgatca
    52381 cgtccaattt tgtctctgaa aacaagttct tttctgttga tatttccatc aactagagcc
    52441 caatattctc tagaaatctc ttttttctcc aataagcgat tgagaatggg caggataaaa
    52501 ggatttttgg caaagagaac taagccactg gtttccatgt ccagacgatg aacgacatag
    52561 caggtttggc caacataggt actgacatgg ttaagaaggg caatttcgtt tggttgatta
    52621 ccatgcgttt tcatcccctc tggtttgttt acaataatca agtgttgatc ttgataaact
    52681 tcctgcacta agtctgggtt gccccaaggg atcgtctttt gggaataatc ttcctcgtca
    52741 aaagtcaact ggcaaacatc tccaggattt acgatttcct tccagtggac ttcttcttga
    52801 tttatcaaaa tatgtttctt gattctcaaa aaatgacgga tttttctagg gatgaggagt
    52861 tgttcctcaa gtaattgctt tactgtcatt tgaggtagag aggcgggtaa tgtaaatgtg
    52921 aattgcatac agatattgta acaaaaaaag ccctatttgg ataggaaata gctaaattct
    52981 tgtcttccta tgatgaagat gataaaataa acgcatgaaa ttagataaat tatttgagaa
    53041 atttctttct ctttttaaaa aagaaacaag tgaactagag gactctgatt ctactatctt
    53101 acgtcgctct cgtagtgatc gaaaaaaatt agcccaagta ggtccgattc gaaaattctg
    53161 gcgtcgttat catctaacaa agattatcct tatactaggt ttgagtgcag gcttgctagt
    53221 tggaatctat ttgtttgctg tagccaagtc gaccaatgtc aatgatttgc aaaatgcctt
    53281 gaaaactcgg actcttattt ttgaccgtga agaaaaagag gctggtgcct tgtctggtca
    53341 aaagggaacc tatgttgagc tgactgacat cagtaaaaac ttgcagaatg ctgttattgc
    53401 gacagaagac cgttctttct ataaaaatga cgggattaac tatggccgtt ttttcttggc
    53461 tattgtcact gctggacgtt caggtggtgg ctctaccatt acccaacagc tggctaaaaa
    53521 cgcctattta tcgcaggatc aaactgttga gagaaaagcg aaagaatttt tccttgcctt
    53581 agaattaagc aaaaaatata gtaaggagca aattctaacc atgtacctta acaacgctta
    53641 ttttggaaat ggtgtgtggg gtgtagaaga tgcgagtaag aaatactttg gagtttctgc
    53701 atcagaagtg agtctggatc aagctgcgac tctggcaggg atgctcaagg ggccggaact
    53761 gtataatccc ttgaattccg tagaagattc tactaatcgg cgcgatactg tcttgcagaa
    53821 tatggttgca gcaggatata ttgataaaaa ccaagaaacc gaagctgctg aagttgatat
    53881 gacttcgcaa ttgcacgata agtatgaagg aaaaatctca gattaccgtt acccctctta
    53941 ttttgatgcg gtggttaatg aagctgtttc caagtataat ctaacagagg aagagattgt
    54001 caataatggc taccgcattt acacagagct ggaccaaaac taccaagcaa atatgcagat
    54061 tgtttatgaa aacacatcgc tatttccgag ggcagaggat ggaacgtttg ctcaatcagg
    54121 aagtgtagct ctcgaaccga aaacaggggg agttcgtgga gttgtcggtc aagttgctga
    54181 caatgataaa actggattcc ggaatttcaa ctatgcaacc caatcaaagc gtagtcctgg
    54241 ttctacaatt aagcctttag ttgtttatac gccagcagtt gaagcaggct gggctttgaa
    54301 taagcagttg gataaccata ccatgcagta tgacagctat aaggttgata actatgcagg
    54361 gatcaaaacg agtcgagaag ttcctatgta tcaagccttg gcagaatcgc ttaatctacc
    54421 tgctgttgcc actgttaatg atttgggtgt cgataaggct tttgaggcag gcgaaaaatt
    54481 cggactcaac atggaaaagg tcgaccgtgt tcttggtgtc gccttgggaa gcggtgttga
    54541 aaccaaccct cttcaaatgg ctcaagcata cgctgccttt gcaaatgaag gtttaatgcc
    54601 tgaagctcat tttattagta gaattgaaaa tgctagtgga caagttattg cgagtcataa
    54661 aaattcacaa aaacgggtga ttgataagtc tgtagctgac aagatgacca gtatgatgtt
    54721 ggggactttc accaacggta ccggtattag ttcatcgcct gcagactata ttatggcagg
    54781 gaaaactgga acaactgaag cagttttcaa tccggagtac acaagtgacc agtgggtaat
    54841 tggttatact ccggatgtag tgattagcca ctggcttggc tttccgacca ctgatgaaaa
    54901 tcactatcta gctggctcta cttcaaacgg tgcagctcat gtctttagaa acattgccaa
    54961 taccatttta ccttatacgc caggaagtac ctttacggtt gaaaatgctt ataagcaaaa
    55021 tggaattgca ccagccaata caaaaagaca agtacaaacc aatgataata gccagacaga
    55081 tgataatttg tctgatattc gagggcgtgc gcaaagtcta gtagatgagg ctagccgggc
    55141 tatctcagat gcgaagatta aggaaaaggc tcaaacaata tgggattcga tagtcaatct
    55201 atttcgctaa gat
//
LOCUS       DAVKMJ010000008        52882 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000008 DAVKMJ010000000
VERSION     DAVKMJ010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 52882)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52882)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52882
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.008"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            265..501
                     /locus_tag="VW348_000490"
     CDS             265..501
                     /locus_tag="VW348_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEU9745444.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            732..2018
                     /locus_tag="VW348_000491"
     CDS             732..2018
                     /locus_tag="VW348_000491"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEU9745445.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            2219..2686
                     /locus_tag="VW348_000492"
     CDS             2219..2686
                     /locus_tag="VW348_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEU9745446.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            2719..2812
                     /gene="ffs"
                     /locus_tag="VW348_000493"
     ncRNA           2719..2812
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VW348_000493"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            2872..3315
                     /locus_tag="VW348_000494"
     CDS             2872..3315
                     /locus_tag="VW348_000494"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEU9745447.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            3317..3832
                     /locus_tag="VW348_000495"
     CDS             3317..3832
                     /locus_tag="VW348_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU9745448.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     TPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            3846..5207
                     /gene="radA"
                     /locus_tag="VW348_000496"
     CDS             3846..5207
                     /gene="radA"
                     /locus_tag="VW348_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEU9745449.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYISGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            5280..5777
                     /locus_tag="VW348_000497"
     CDS             5280..5777
                     /locus_tag="VW348_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEU9745450.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            5798..6142
                     /locus_tag="VW348_000498"
     CDS             5798..6142
                     /locus_tag="VW348_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745451.1"
                     /translation="MYEEKQYFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFANTYIHDFMNCTPKV
                     RQKKSNFWGVLL"
     gene            6139..7490
                     /locus_tag="VW348_000499"
     CDS             join(6139..6580,6580..7490)
                     /locus_tag="VW348_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEU9745452.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSISLDYALPNQGMLSFWPAQYKKN
                     GYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENERLRTEVAYPKKVKRVRGKGRS
                     PRARKAETVREMVSGGFRLDFLLETARLARSTYYYQLKQLDGVDKDKEIKTEIQGIDN
                     EHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPVLDGFNSEIIAYHLSTSPNLEQ
                     VKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNSMME
                     SFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNNKRIKVKLKGLSSVQYRTKSFG
                     "
     gene            7496..8056
                     /locus_tag="VW348_000500"
     CDS             7496..8056
                     /locus_tag="VW348_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEU9745453.1"
                     /translation="MSNFLGSVHLLGVLFPDSTFLNAFESAIVAPLVEESLKLLPLVF
                     VLALIPVRKLKSLFLLGIASGLGFQMIEDIGYIHTDLPEGFDFTISRILERIISGIAS
                     HWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLALGTHFLFNSPFVELETELPLAI
                     PVVTAIALYGFYHAYCFVEKHNELMT"
     gene            8201..9169
                     /locus_tag="VW348_000501"
     CDS             8201..9169
                     /locus_tag="VW348_000501"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU9745454.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            9287..9640
                     /locus_tag="VW348_000502"
     CDS             9287..9640
                     /locus_tag="VW348_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU9745455.1"
                     /translation="MTVRHPGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAQNVTIL
                     EGSNIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQV
                     NQNLEKIRQREGDTH"
     gene            9855..9971
                     /locus_tag="VW348_000503"
     CDS             9855..9971
                     /locus_tag="VW348_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEU9745456.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            9964..10214
                     /locus_tag="VW348_000504"
                     /pseudo
     CDS             9964..10214
                     /locus_tag="VW348_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866636.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            10823..13456
                     /gene="polA"
                     /locus_tag="VW348_000505"
     CDS             10823..13456
                     /gene="polA"
                     /locus_tag="VW348_000505"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEU9745457.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVGTEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            13541..13978
                     /locus_tag="VW348_000506"
     CDS             13541..13978
                     /locus_tag="VW348_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEU9745458.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(14214..15224)
                     /locus_tag="VW348_000507"
     CDS             complement(14214..15224)
                     /locus_tag="VW348_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEU9745459.1"
                     /translation="MSFLSKNGAGILACLLISILSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIVMAMSAIGLKTNLVAMVKSSGKSIVLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            15373..16542
                     /locus_tag="VW348_000508"
     CDS             15373..16542
                     /locus_tag="VW348_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9745460.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEVFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            16539..17309
                     /gene="recO"
                     /locus_tag="VW348_000509"
     CDS             16539..17309
                     /gene="recO"
                     /locus_tag="VW348_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEU9745461.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKCMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            17306..18298
                     /gene="plsX"
                     /locus_tag="VW348_000510"
     CDS             17306..18298
                     /gene="plsX"
                     /locus_tag="VW348_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEU9745462.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            18304..18537
                     /locus_tag="VW348_000511"
     CDS             18304..18537
                     /locus_tag="VW348_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU9745463.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            18583..18873
                     /locus_tag="VW348_000512"
                     /pseudo
     CDS             18583..18873
                     /locus_tag="VW348_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            19076..19306
                     /gene="blpU"
                     /locus_tag="VW348_000513"
     CDS             19076..19306
                     /gene="blpU"
                     /locus_tag="VW348_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEU9745464.1"
                     /translation="MNTKTMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            20021..22174
                     /locus_tag="VW348_000514"
     CDS             20021..22174
                     /locus_tag="VW348_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEU9745465.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            22187..23536
                     /locus_tag="VW348_000515"
     CDS             22187..23536
                     /locus_tag="VW348_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEU9745466.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKVTASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKYVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            23706..24413
                     /locus_tag="VW348_000516"
     CDS             23706..24413
                     /locus_tag="VW348_000516"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEU9745467.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNVAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            24415..24558
                     /locus_tag="VW348_000517"
     CDS             24415..24558
                     /locus_tag="VW348_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEU9745468.1"
                     /translation="MFATENLRLSTKRTQAEKVPQTFSLCRELGELTDVYEIVWEKLQ
                     GLK"
     gene            24615..28340
                     /locus_tag="VW348_000518"
     CDS             24615..28340
                     /locus_tag="VW348_000518"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEU9745469.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            28433..29875
                     /locus_tag="VW348_000519"
     CDS             28433..29875
                     /locus_tag="VW348_000519"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEU9745470.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGVEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            30094..31116
                     /locus_tag="VW348_000520"
     CDS             30094..31116
                     /locus_tag="VW348_000520"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEU9745471.1"
                     /translation="MANKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIAGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            31113..31658
                     /gene="purN"
                     /locus_tag="VW348_000521"
     CDS             31113..31658
                     /gene="purN"
                     /locus_tag="VW348_000521"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEU9745472.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKTDYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            31742..32251
                     /locus_tag="VW348_000522"
     CDS             31742..32251
                     /locus_tag="VW348_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU9745473.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            32276..33823
                     /gene="purH"
                     /locus_tag="VW348_000523"
     CDS             32276..33823
                     /gene="purH"
                     /locus_tag="VW348_000523"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEU9745474.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     ETIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAANENQIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            33945..35207
                     /gene="purD"
                     /locus_tag="VW348_000524"
     CDS             33945..35207
                     /gene="purD"
                     /locus_tag="VW348_000524"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEU9745475.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVPTATYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGVIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNIMWTDKGVTLGVVVA
                     SKGYPLDYERGVELPAKTEGDVITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            35610..36098
                     /gene="purE"
                     /locus_tag="VW348_000525"
     CDS             35610..36098
                     /gene="purE"
                     /locus_tag="VW348_000525"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEU9745476.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            36085..37176
                     /gene="purK"
                     /locus_tag="VW348_000526"
     CDS             36085..37176
                     /gene="purK"
                     /locus_tag="VW348_000526"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEU9745477.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            37186..37413
                     /locus_tag="VW348_000527"
     CDS             37186..37413
                     /locus_tag="VW348_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEU9745478.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            37476..38774
                     /gene="purB"
                     /locus_tag="VW348_000528"
     CDS             37476..38774
                     /gene="purB"
                     /locus_tag="VW348_000528"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEU9745479.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(38829..42767)
                     /gene="strH"
                     /locus_tag="VW348_000529"
     CDS             complement(38829..42767)
                     /gene="strH"
                     /locus_tag="VW348_000529"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU9745480.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLETLDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(43082..43798)
                     /locus_tag="VW348_000530"
     CDS             complement(43082..43798)
                     /locus_tag="VW348_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9745481.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            44146..45933
                     /locus_tag="VW348_000531"
     CDS             44146..45933
                     /locus_tag="VW348_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEU9745482.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFDGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            45930..46406
                     /locus_tag="VW348_000532"
     CDS             45930..46406
                     /locus_tag="VW348_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU9745483.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            46434..47339
                     /locus_tag="VW348_000533"
     CDS             46434..47339
                     /locus_tag="VW348_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU9745484.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            47326..48141
                     /locus_tag="VW348_000534"
     CDS             47326..48141
                     /locus_tag="VW348_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9745485.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            48148..48552
                     /locus_tag="VW348_000535"
     CDS             48148..48552
                     /locus_tag="VW348_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9745486.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            48805..49971
                     /locus_tag="VW348_000536"
     CDS             48805..49971
                     /locus_tag="VW348_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEU9745487.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCATDGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKV
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTAYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVVLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            50087..51124
                     /locus_tag="VW348_000537"
     CDS             50087..51124
                     /locus_tag="VW348_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEU9745488.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     IYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            51332..52186
                     /locus_tag="VW348_000538"
     CDS             51332..52186
                     /locus_tag="VW348_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9745489.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWNIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLENKFSVPGASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            52336..52593
                     /locus_tag="VW348_000539"
     CDS             52336..52593
                     /locus_tag="VW348_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HEU9745490.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVKSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
BASE COUNT        14930 a         9826 c        12570 g        15556 t
ORIGIN      
        1 tgaatttttt tatactagaa aatcagaacc ataataccta tataaaaata ttatagtttt
       61 aataggattt acccaaaagt tttaaggcgg tctttttaga actttaattg tttgaaattt
      121 aggtagcaaa tttgtttcta ttttgtcaac ttttcctatt tttatcttgt tgaggctggt
      181 attttaacaa ttcaggaatt gatagtgaat gtgtaaaatt ttttgttaga ataagtttat
      241 aaaaaagaaa aggagtattt gattatgtta caaaaaattt atgagcagat ggctaatttc
      301 tatgatagta ttgaagaaga gtatggtcct acatttggtg ataattttga ctgggaacat
      361 gttcatttta aatttttaat ttattattta gtgagatatg gcattggttg tcgtagggat
      421 tttatcgttt accattatcg tgttgcttat cgtttgtatc ttgaaaaatt ggtaatgaat
      481 cgggggttta tttcttgttg aggtaatttt agtaaatttc cgaactaatt tactctttta
      541 tggaaagata atagtaaata gctagtaatt tttctaaatc attttttaat agttggaaat
      601 agcaaatctt tctattgttt cttcttgata aaaaggcgat tttttattat aataaattgt
      661 aagatataat tgcaggtgag agtcctgcca tgtatgtgag aaaggaagag cctgagggct
      721 cagacaaaat tatgacttca gttgttgttg taggtaccca atggggtgat gaaggtaaag
      781 ggaagattac agacttcctt tcagcgaatg cagaagtaat tgcacgttac caaggtggtg
      841 ataatgctgg tcacacgatt gtgattgacg gtaagaaatt taagttgcac ttgattccat
      901 ctgggatttt cttccctgaa aaaatatctg tcattgggaa tggtatggtt gtaaatccta
      961 aatctcttgt aaaagagttg agctatcttc atgaggaagg tgtaacaact gataacttgc
     1021 gtatttctga tcgtgcgcat gttattttgc cttatcatat cgagttggat cgcttgcaag
     1081 aagaagctaa gggcgacaat aagattggta cgacaattaa gggaattggt ccagcttata
     1141 tggacaaggc tgctcgtgtt ggaattcgta ttgcagatct tttagataaa gatattttcc
     1201 gtgagcgttt agaacgtaac cttgctgaaa agaatcgtct ttttgaaaaa ttgtatgaca
     1261 gtaaagcgat tgttttcgat gatatttttg aagaatatta cgaatatggt caacaaatca
     1321 agaaatacgt gatagataca tctgttatct tgaatgatgc gcttgataat ggcaaacgtg
     1381 tgctttttga aggtgcacaa ggtgttatgc tagatatcga ccaaggtact tatccatttg
     1441 ttacgtcatc aaaccctgta gctggtggtg tgacaattgg ttctggtgtc ggtccaagca
     1501 agattgacaa ggttgtaggt gtatgtaaag cttatacgag tcgtgtagga gatggtcctt
     1561 tcccaactga gttgtttgat gaagtgggag aacgtatccg tgaagtgggt catgaatatg
     1621 gtacaacaac tggtcgtcca cgtcgtgtag gttggtttga ctcagttgtg atgcgtcata
     1681 gccgtcgtgt ttctggtatt actaaccttt ctttgaactc tattgatgtt ttgagcggtt
     1741 tggatactgt gaaaatctgt gtggcctatg atcttgacgg tcaacgtatt gactactatc
     1801 cagctagtct tgagcaattg aaacgttgca agcctatcta tgaagagttg ccaggttggt
     1861 cagaagatat taccggagtt cgcaatttgg aagatcttcc tgagaatgcg cgtaactatg
     1921 ttcgtcgtgt gagtgaattg gttggcgttc gtatttctac tttctcagta ggtcctggtc
     1981 gtgaacaaac aaatatttta gaaagtgttt ggtcctaaga gatttttaag atttgtttaa
     2041 gataggtcgg gtatactata gacggttaca agaagacctc ctaacttgtt gtaacaaata
     2101 tcctaaactt ttctttttca taataatctc cctatagagt caccgcattc ggtggcttct
     2161 tttgtgttgg gattcatgat ataataataa aatcgataag taggaaaaga gaaaagagat
     2221 gtattatacg cttgaagaaa aagaagtctt tatgagggag gctttgagag aggctgagat
     2281 tgctcttgaa cacgatgaaa ttccaattgg ttgtgtgatt gtcaaagatg gggaaatcat
     2341 tggtcgtggg cataatgcgc gtgaggaatt acagcgagcg gttatgcatg cggaaattat
     2401 ggctatagag gatgcgaact tgagtgagga gagctggcgc ttgctggatt gcacactttt
     2461 tgtgaccatt gaaccttgtg tcatgtgtag tggagcgatt gggcttgccc gcattccaaa
     2521 tgtggtctat ggggctaaaa accagaaatt tggcgctgct gggagtttgt acaatatctt
     2581 gacagatgag cgtctcaatc atcgtgtgga ggttgaaata ggaattttgg aagatgaatg
     2641 cgcagctatc atgcaggatt tttttagaaa tagacggaaa aaataatttt gcttttaaaa
     2701 tgaataggaa tgtgatataa taaatagtgg agcaacagtt ctgcgtgaag cgggtcaggg
     2761 gaggaatcca gcagccctaa gcgatttgaa ttgtgtgctc ttttttcgtg ctttttccga
     2821 ataaataaga tagaataatc tagaataaat gataatagaa aagagaaaat tatgaaaatt
     2881 cgtggttttg aattggtttc gagttttaca gatgaaaatt tattgcccaa gcgtgagaca
     2941 gcgcatgcgg ctggttacga cttaaaggtt gctgtgcgta cagttgttgc gccaggagag
     3001 attgtcttgg ttccgacagg ggttaaggct tatatgcagc cgactgaggt tctctacctc
     3061 tatgatcgtt cttcaaatcc tcgtaagaag ggcttggttt taattaactc agttggggtc
     3121 attgatgggg attattatgg aaatcctgga aatgaagggc atatttttgc gcagatgaag
     3181 aatatcacag accaagaggt tgttcttgaa gttggggaac gtattgtcca ggctgttttt
     3241 gctactttct taattgcaga tggagatgca gctgatggcg ttcgaactgg tggatttgga
     3301 tcgacagggc actagaatga agattatctt tgtacgtcat ggggagccag attaccgtga
     3361 gttagaggag cgttcttata taggatttgg gatagatttg gcacccttgt ctgagatggg
     3421 acggcagcaa gtccagaaat tgagcaaaac tcctttactc tcgtcagctg aaataatcgt
     3481 atcttctgca gtcacaagag ctttagaaac ggcttcgtat gtggtctgtg ctacgggtct
     3541 tcctttaaga gtagagcctt tattacatga atggcaggtc tataaaacag gaatagaaaa
     3601 ctttgaaaca gctagaagac tgtttttaga aaacaagggg gagttgcttc ctaatagtcc
     3661 tattcaatat gagacagcta cggaaatgaa gtctcggttt ctagaatgta tgtctaagta
     3721 tcgagaacat cagactgtgg tagttgttgc tcatcgaatg ctcatgcgcc agtttgtgcc
     3781 aaatgagaag attgattttt gccaagtgat tgagtgtgag ttagagatat agaaagaggt
     3841 ttgtcatcgc aaagaaaaaa gcgacatttg tatgtcaaaa ttgtgggtat aattccccta
     3901 aatatctggg acgttgcccc aactgtgggt cttggtcttc ttttgtggaa gaggttgagg
     3961 ttgccgaggt caagaatgcg cgtgtgtcct tgacaggtga gaaaaccaag cccatgaaac
     4021 tagctgaggt gacttccatc aatgtcaatc gaaccaagac ggagatggag gaattcaacc
     4081 gtgtgcttgg aggcggagtg gtaccaggaa gtctcgtcct catcggtggg gatcctggga
     4141 ttgggaaatc aactcttctc ctacaagtct caacccagtt gtcccaagtg gggacagttc
     4201 tctatatcag tggggaggag tctgcccagc agattaaact acgtgcagag cgcttaggtg
     4261 atattgatag tgagttttat ctctatgcag agaccaatat gcagagtgtt cgtgcagaag
     4321 tggagcgtat ccagccagac tttcttatta ttgattccat ccagaccatc atgtctcctg
     4381 agatttcagg ggtgcagggg tctgtttctc aggtacgtga agtgaccgct gaactcatgc
     4441 agttggccaa gaccaataac attgccatct ttatcgtagg tcatgtgacc aaagaaggaa
     4501 ccttggctgg gcctcgtatg ttggagcata tggtggatac ggtgctttac tttgaagggg
     4561 agcgtcacca cacctttcgt attttgagag cggtcaaaaa tcgttttggt tccactaatg
     4621 agattgggat ttttgagatg cagtcgggcg gcttggttga ggtactcaat ccgagtcaag
     4681 ttttcctaga agagcgtttg gatggggcaa ctggttcctc catcgttgta accatggaag
     4741 ggacgcgtcc gattttggcg gaggttcagg ctttggtaac accgaccatg tttggaaatg
     4801 ccaagcgtac tacgacagga cttgatttta accgtgctag cttgattatg gctgttttgg
     4861 aaaaacgggc agggcttctc ttgcaaaatc aggatgccta tctcaaatct gctggtggtg
     4921 ttaaattgga tgaacctgcc attgacttgg ctgttgcagt tgctattgct tcgagctaca
     4981 aagacaagcc aactaatcct caggaatgtt ttgtcggaga actgggcttg acaggagaga
     5041 ttcggcgcgt gaatcgtatt gagcaacgca tcaacgaagc tgctaaactg ggctttacta
     5101 agatttatgt acctaagaat tccttgacag gaatcactct gcctaaggaa attcaggtca
     5161 ttggcgtgac aacgattcag gaagttttga aaaaggtctt tgcataatcc gtgacaaatt
     5221 ctcttaaaaa tgataagata ggagaaatat ttgactatca aattttcaag gagggaatcg
     5281 tgtcgtattt tgaacagttt atgcaagcta atcaggctta tgttgcccta catgggcagt
     5341 taaatctgcc acttaaaccc aaaacaagag tagctattgt gacctgtatg gactcacgtt
     5401 tgcacgttgc gcaagctcta ggtttggcac ttggggatgc tcatatcttg cggaatgcag
     5461 gtggtcgagt gactgaagac atgattcgtt cgctagttat ttcccagcaa caaatgggga
     5521 caagagagat tgtggtattg caccatacag actgtggtgc tcagaccttt gaaaatgaac
     5581 cttttcagga gtatttaaaa gaggaattag gtgtagatgt gtcagaccag gacttcttgc
     5641 ccttccaaga tatagaagag agtgtacgcg aggatatgca actgcttatc gagtctcccc
     5701 taataccaga cgatgtcatt atctctggtg ctatttacaa tgttgataca ggaagtatga
     5761 cagtcgtaga attataaata cttcatttag aaagaaagtg tatgaagaaa agcagtattt
     5821 tatttttatt ttattgctat gtattggttt acagtatgaa accatctact atacggacgg
     5881 ttcgaggtca ggtgcggaat atggactaat gggagtttct atctttctag ctctctttta
     5941 catgattccg gctctttatt ttctcttccg tattgggaaa aaatgggaat tgccaaagaa
     6001 ggttttgatt ctgtctttat tgggagggat gttcctttca ggctggttgt ctagttttgc
     6061 taatacttat atccatgatt ttatgaactg caccccaaaa gttagacaga aaaaatctaa
     6121 cttttggggt gttttattat gaaattgagt tatgaagata aagttcagat ctatgaacta
     6181 agaaagcaag gacaaagctt caaacagctt tcaaaaagat ttggtgtgga tgtttctggt
     6241 ctaaagtaca tggtgaaatt aattgaccgt tatggcatag aaatcgttaa aaaagggaag
     6301 aatcgtcact attcttctaa attgaaacaa gaaatgatgg ataaagcctt actggaaggt
     6361 tgttcacaaa gaagtattag tcttgattat gccctcccaa accaaggaat gctttcattt
     6421 tggccggcac aatacaagaa aaacgggtat actattgttg agaaaacaag agggagacca
     6481 gctaaaatgg gacgtaaacg gaagaagact tgggaagaaa tgacagaact agaacgactc
     6541 caggaggaga atgaacgctt acggactgag gtggcctacc taaaaaagtt aaaagagtta
     6601 gaggaaaggg acgaagccct agagcgagaa aggcagagac agttagagaa atggtttcag
     6661 gaggatttcg actagatttt cttcttgaaa cagcacgttt agctcgctcg acttactatt
     6721 atcagttgaa acaactggat ggggttgata aagataaaga gattaaaacc gaaattcagg
     6781 gcattgataa tgaacataaa ggcaactatg gctatcgtcg aatccattta gaactaagga
     6841 atcgtggttt tgtggtcaat cataagaaag ttcaacggtt gatgagaatt cttggtttaa
     6901 cggctcgaat tcgccgtaaa cggaagtatt cttcctacca aggagagatt ggcaagaaag
     6961 cagagaatct cattcaacgc cagttcgaag catcgaggcc aatggaaaag tgctatacag
     7021 atgtgacaga gtttgccatt ccaaatagca cacagaaact ctatttatca ccagttttag
     7081 atggttttaa cagtgaaatc attgcttatc atctttctac ttcgccaaac ttagaacaag
     7141 tgaagagtat gttagaacag gcctttacag agaaatacta tgagaatacg attctccata
     7201 gtgaccaagg ctggcaatac caacacgatt cttatcatcg gttcctagag agtaagggaa
     7261 ttcaagcatc catgtcacgc aagggcaaca gcccagacaa cagcatgatg gaatctttct
     7321 ttggcatttt aaaatccgaa atgttttatg gctatgagaa gaactttaga tctttagaaa
     7381 accttgaaca agctattgtg gactacattg attactacaa caacaaacga attaaggtaa
     7441 aactaaaagg acttagttct gtgcagtaca gaactaaatc ctttggataa attatttgtc
     7501 taactttttg gggtcagtac atttactggg ggttcttttc ccagatagta catttttaaa
     7561 tgcctttgaa agtgctattg tggctccttt ggtagaagaa tccttgaaat tattgccact
     7621 tgtttttgtt ttggctttga ttcctgtgcg aaaattaaaa tctttgtttt tacttggaat
     7681 tgcttccggt ttgggattcc aaatgattga ggatattggt tatattcata cggatttgcc
     7741 agagggcttt gactttacta tttcgcgaat tttagagcgt atcatctcag gaattgcctc
     7801 tcactggact ttttcaggtc tagctgtagt aggtgtttac ttgctttaca gagcctataa
     7861 aggacagaag gttggcaaga aacagggcct tatttttcta ggtttagcct tgggaactca
     7921 cttcttgttt aactctcctt ttgtggagtt ggaaacagag ttgcctttag cgattccagt
     7981 ggttacggct attgctctct atggttttta tcatgcttat tgctttgttg agaaacacaa
     8041 tgagttgatg acctagaata tttttcaaaa gaatgatgca agggtacaaa tatggtgccc
     8101 ttcttttatt tttgattgaa aaatagtgca aaaagcgcta caatggtaga tggaaaatct
     8161 tgtgaaaagc acaagttata catatatacc ggaggaaatc atgtcttttt ctgatttaaa
     8221 gctatttgcc ctttcttcta ataaagaatt ggcagaacgt gtggcgcagg agattgggat
     8281 agagttgggg aaatcaagtg ttcgccaatt ttcagatgga gagattcagg tcaacattga
     8341 agaatcaatc cgtgggaaac acgtctttat cctacaatca actagttcgc ctgtaaatga
     8401 caatctgctt gaaattttga ttatggtaga tgctttgaag cgtgcgagtg cagaatctgt
     8461 caatgttgtc atgccttact atgggtatgc acgtcaggat agaaaggcga gagcgcgtga
     8521 gccaatcact tcaaaacttg tcgcaaatat gcttgaagta gctggagtgg atcgtttatt
     8581 gaccatcgac ttgcatgctg cgcaaattca aggattcttt gatattcctg tggatcattt
     8641 gatgggtgct cctctgattg cagattattt tgagcgtcgt ggtatggttg gttctgacta
     8701 tgtggttgtc agcccggacc atggaggggt gactcgtgct cgtaagttgg cagaattttt
     8761 gaaaacttct atcgctatta ttgataaacg tcgtagcgtt gataagatga atactagtga
     8821 agttatgaac atcatcggta aggttgaagg caagacttgt atcttgattg atgatatgat
     8881 tgataccgct ggaacgattt gtcatgcggc agatgctctt gcggaagctg gtgctgttga
     8941 agtctatgca agctgtacgc acccagttct ttctggtcct gctacggaca atatccaaaa
     9001 atcagctatt aagaaattgg ttgttttgga taccatctat ctgccagaag agcgtttgat
     9061 tgataagatt gagcagattt caatcgctca tctcctaggg gatgctatcg tacgtattca
     9121 tgaaaaacga ccactttctc cacttttcga tattgagaaa aaaatttaat gaccaagcct
     9181 gagatgattc tcaggttttt tcgtcttttt tccgaataaa tagatagtag cggtgaatct
     9241 agtaaagcta gatttaaaac tgtgatataa taaaaagaga agaaatatga ctgtacgtca
     9301 tccgggcatt agcccaacca atgacttggt agctaagaaa atctttagca atccagaaat
     9361 tacttgtcaa tttattcgcg atatgctgga tttgccagcc caaaatgtga ccattttgga
     9421 gggtagcaat attcacgtat tactctccat gccttactcg gtgcaggatt tttataccag
     9481 tatagacgtc ttggcggagt tggataacgg tactcaagta attattgaga ttcaagtcca
     9541 tcatcagaat tttttcatca atcacttgtg ggcttacctg tgcagtcagg ttaatcaaaa
     9601 tcttgaaaaa attcgtcagc gagaaggtga tactcactag atctacaaac acatcgctcc
     9661 tgtttacgtc attgctatcg tggatagcaa ttatttctca gatggcctgg cttttcatag
     9721 cgttagtatg cgcgaagaca caacaggtga ggtattggcg attaccaaca atggacagga
     9781 aaaccatctg gttaagatgg cattcttgga attaaaaaat acagagaaac cagcaaagac
     9841 aaggttcgca agccatggtt ggagtttttc ggcaacaagc cctttaccca gcaaccgcaa
     9901 cgagccatta cccaagcaaa tcaactgctg gactacaaga gctggtccga ggaggacagg
     9961 aaaatgttta gtcaactaca tatgcgagaa gaacaagtct tgttagcaca ggactatgcg
    10021 aaggtattga acaaggacta gagcgtggta ttgaacgtgg tcgtgcagag ggttgtgaac
    10081 aaggacgaga agaaggcctt gaagagggat taaaagtagg tttagtaaat ctagtacgtc
    10141 aaggtcttct aacacctgag gttgcgagtg agcaattagg catgaccgtg gctgagtttg
    10201 agtccttgct atgagttcat actttatata gtagaaagtt gatgggatgg caagtttatt
    10261 atcaaaatac ttgtcatttt tgcttgacat ttctatcttt ttataagata tagtaaaatg
    10321 aaataataac aggacaaatc gttcaggaca gtcaaatcga tttctaacaa tgttttagaa
    10381 atcgaggtgt actattctag tttcaatcta ctatagtatt agcgaagtaa gttatgtctc
    10441 gctattcgta cagtttggat agtcgcaaga ttgtctttga aatttcctgt tttaaagaga
    10501 aaaaagcctc tttgacgcta ttttttcatc tttttgaaag ttctataatg aagttagcca
    10561 cccagccctc cttttcctcc ttctatagtg agttgaaata agatgtgaaa caactctatc
    10621 aggaaagtca aattaattta tagaaatatt ttagcagtca aggtgtacta ttatagattc
    10681 aatatactat attatatcac atttttaaat ctaggtttac taaattctct ggctctatct
    10741 atttattcgg aaaaagtttg aaaaatactt gctctagctc ttcccaatgg tattttttga
    10801 ttctttcctt tataatgggt gtatggataa gaaaaaatta ttattgattg atgggtcttc
    10861 tgtagctttt cgggcgtttt ttgcgctgta tcagcagttg gaccgtttta agaatgcggc
    10921 tggtttgcat accaatgcga tttatggttt tcagttgatg ttgagtcatt tgttggagcg
    10981 ggttgagccg agtcatattt tggtggcttt tgatgcggga aagacgacct tccggacaga
    11041 gatgtatgcg gactataagg gtggtcgggc caagactcct gatgagtttc gtgagcaatt
    11101 tcctttcatt cgtgagttgc tggatcatat ggggattcgt cactatgagc tggctcagta
    11161 tgaggcggat gacatcattg ggacgctgga taagctagca gagcaggatg gttttgatat
    11221 taccattgtc agtggggaca aggatttgat tcagctgacg gatgagcata cggtggttga
    11281 aatttccaag aaaggtgtgg ctgagtttga ggcctttacg ccagattacc tcatggaaga
    11341 aatgggcctc acaccagctc agtttatcga tctcaaggcg ctcatgggtg ataagtcgga
    11401 taatatccct ggggtgacca aagtcggtga aaagacgggt attaagctct tgctggagca
    11461 tggttcgctt gaggggattt atgaaaatat tgatggaatg aagacttcta agatgaagga
    11521 aaatctcatc aatgacaagg aacaggcctt tttgtctaaa acactagcga ccattgatac
    11581 caaggcaccg attgcgattg gtttagagga cttggtctat agtggtccag atgttgaaaa
    11641 tcttgggaaa ttttacgatg agatgggctt caaacagctc aagcaggctt taaatgtgtc
    11701 gtcagctgat gtggctgagg gtttggattt tactattgtt gaccaaatca gtcaagatat
    11761 gctgagtgaa gagtctatct tccactttga gctttttggt gagaattacc atacggataa
    11821 tttggttgga tttgcctggt cttgtgggga taagctctat gccacagaca agcttgagct
    11881 gttgcaagac ccgattttca aggatttctt agaaaaaaca tctctgagag tttatgactt
    11941 taagaaggtt aaagttcttt tgcaacgttt tggtgtggat ttgcaggcgc ctgcttttga
    12001 catccgtttg gctaaatacc tcctttcgac tgtggaggac aatgaaattg cgaccatcgc
    12061 tagtctttat ggtcagactt acttggttga tgatgaaact ttctacggta agggtgttaa
    12121 aaaggccatt cctgaacgtg agaaattctt ggaacactta gcttgtaaac ttgctgtttt
    12181 ggtaggaaca gagcctattt tacttgaaaa actcagcgaa aatgggcaat tagagcttct
    12241 ttatgatatg gagcaacctc tggcttttgt tcttgccaag atggaaattg ctgggattgt
    12301 ggtcaagaaa gagaccttgc ttgagatgca ggctgaaaat gagcttgtca ttgaaaaact
    12361 gactcaagag atttacgagc tggctggtga ggagtttaat gtcaactcgc ctaagcagtt
    12421 gggcgtgctt ctctttgaga aattgggact tcctctagaa tacactaaga aaaccaagac
    12481 aggttattcg acagcagtgg atgtgttgga gcgtctcgct cctattgctc cgattgttaa
    12541 gaaaatcctg gattaccgtc aaattgctaa gattcaatct acttatgtaa ttggcttgca
    12601 ggactggatt ttggctgatg gaaagattca tactcgctat atgcaggatt tgacccagac
    12661 cgggcgtttg tctagtgtgg atccaaactt gcaaaatatt cctgctcgat tggaacaagg
    12721 gcgcttgatt cggaaggctt ttgtgccaga gtgggaggat agtgtgctac tcagctctga
    12781 ctattcacag attgaattgc gcgttttggc gcatatttct aaggatgagc acttgattaa
    12841 ggccttccaa gagggggcag atatccatac ttcgacagcc atgcgggtct ttggcattga
    12901 gcgtcctgat aatgtgactg caaatgaccg tcgcaatgcc aaggcagtta actttggagt
    12961 ggtttatggg atttcagact ttggcttgtc taataatttg ggaattagtc gtaaggaagc
    13021 caaagcctac attgatacct actttgaacg ttttccaggt attaaaaact acatggatga
    13081 agtggtgcgg gaggcgcgtg ataagggcta tgtagagacc ctctttaagc gtcgccgtga
    13141 gttgccagat atcaattcgc gcaacttcaa tattcgtggt tttgcggagc gaactgctat
    13201 caactcacct atccagggtt cggcagcaga tattctcaag attgccatga ttcagctgga
    13261 taaagccttg gttgcaggtg gttatcagac taagatgctg ttacaagtgc acgatgaaat
    13321 cgtccttgaa gtgcctaaat ctgaattggt agagatgaaa aaattggtga aacaaaccat
    13381 ggaagaagcc attcaactca gtgttcctct tatcgcagat gagaatgaag gggcaacctg
    13441 gtacgaggct aaataaaaag ggggctagtc ctcctttttt gtagtagaat tctgcaaacc
    13501 ttttcaaaat gtgctatact gatgaaaaag gaggatttct atgagtcaag aatttatcaa
    13561 tccaagtgat ggcgtgattc gtcagtatct cgcaacgagt aaaacccttg ctgtggtggg
    13621 tttgtctgac cgtgaagaaa caactagcaa tcgagtaaca aaggaaatgc aggctcgggg
    13681 ctataaaatc atcccagtca atcccaaggc ggcaggtggc gaaatcttgg gtgaaaaggc
    13741 ttatgctagc ctcgctgaaa ttccttttcc tgtagatatt gtcaatgttt atcgtcgcag
    13801 tgaatttctg cccgatgtgg cgcgtgattt tctcaaagct gatgccaaga ttttttgggc
    13861 acagctagga cttgaaagtt tagaagcgaa agagattttg cgtgatggtg gatgtgatga
    13921 tatcgtgatg aatcgctgta tcaagagaga acatactcgc ttgattgagg aagcataaga
    13981 aaaaggtagc tgatgggcta ccttttgtgt tatactcaat gaaaatcaaa gagcaaacta
    14041 gcaaactagg aaactagccg cgggctgctc aaaacactgt tttgaggttg tagatagaac
    14101 tgacgaagtc agctcaaaac accgttttga ggttgcagat agaactgacg aagtcagtaa
    14161 catatatacg gcaaggcgac gttgacgtgg tttgaagaga ttttcgaaga gtattagaaa
    14221 atgccgataa gggtctgcat accaagagtg gtgaggatga tggcaatcca gcagatggct
    14281 ccgagaacaa tggattttcc actggatttg accatagcga ccagattggt tttgagaccg
    14341 atagcactca tggccatgac aatgaggaat ttagagagtt gtttgagagg ggtaaagaaa
    14401 ctactagaca caccgagaga ggtcagaagg gtggttagga gcgatgcaag gataaagtaa
    14461 aggataaaaa gtgggaagac ttttttcagt tgtaggcttt gcttgttttc ttgttggcga
    14521 ctttgccagt aggatagaaa gagcgtgata gggataatgg ccaaagtacg tgtgagttta
    14581 acaatggttg cagactcgag ggtattgctt tggtaaagac tgtcccaagc gctggcggca
    14641 gccgttacag aggaagtgtc gttgaccgca gtccctgcaa agagggcgaa gccttcattg
    14701 gatagatgaa gccaggtgcc gagggttgga aagatgagcg cagccaagac attgaagaaa
    14761 aagataacgg aaatggcttg ggctacttcc ttttccttag catcaataac gggcgctgtc
    14821 gctgcaatgg cagaaccccc acagatagaa gaacctactc caaccaaggt agccagtttt
    14881 gtatccagtg caaagaaacg ctggaagagg taggcaataa tcagagctat tgagatagtg
    14941 gacaggatga cagggagtga agattggcca actgcgaaga cctgcgagat attgagacca
    15001 aaaccaagca agacaacggc atattggagc aacttcttgg aactaaaggt caaaccagca
    15061 tccagttgtt tataggacga gagaaaggga tgtaggagca tgcctatgaa aatggcaaaa
    15121 acgggcgcgc caatcacagg gaagaatcct cctaagtacc aagataggat ggaaatgaga
    15181 aggcaggcca agatacctgc tccatttttt gatagaaatg acataaaaac ctccaaataa
    15241 aatctattac cattatagac ctataaacag gaaaagtaaa atagaaagtg gaaagctatt
    15301 ctctaatgta tttttgcggt cggggggctt ttgtagtata atagagatac gttttgaaag
    15361 taggaggtat ctatggactt aactaagcgc tttaataaac agttagataa aattcaagtt
    15421 tcgttgattc gtcagtttga ccaggctatt tcggagattc ctggggtctt gcgtttgacc
    15481 ttgggggaac ctgattttac aacgccagac catgtcaagg aggcggccaa gcgagcgatt
    15541 gatcagaacc aatcctacta tacagggatg agtggtctgc tgactctacg tcaggcagcc
    15601 agtgactttg ttaaggaaaa gtaccaactg gactatgctc ctgaaaatga aatcttggtt
    15661 acaattgggg cgacagaggc tttatctgcg actttgacgg ctattttgga agagggagac
    15721 aaggtacttt tgccagctcc tgcttatcca ggctatgaac cgattgttaa cttagttggg
    15781 gcagaaattg ttgagattga tacgactgaa aatggttttg tcttgactcc tgagatgttg
    15841 gagaaggcca ttttggagca gggtgataag ctcaaagcgg ttattctcaa ctatccagcc
    15901 aatccgacag gaattaccta cagtcgagag cagttagagg ccttggcagc tgttttacgc
    15961 aagtacgaag tttttgttgt ctgtgatgag gtttactcag aattgaccta cacaggcgaa
    16021 gcccatgtgt ctctaggaac gatgttgaga gaccaggcta ttattatcaa tggtttgtct
    16081 aaatcgcatg ccatgacagg ttggcgtttg gggctgattt tcgctccggc gaccttcaca
    16141 gcccagttaa tcaagagtca ccagtacttg gtcactgccg caaataccat ggcgcaacat
    16201 gctgcggtag aagccttgac ggctggtaaa aatgatgcgg agcccatgaa gaaggaatat
    16261 atccagcgtc gggactatat catcgaaaaa atgactgctc ttggttttga gattatcaaa
    16321 ccagacggtg ccttctatat ttttgctaaa attccagcgg gctacaatca agactccttt
    16381 gcttttctga aggattttgc tcagaagaag gccgttgcct ttatccctgg tgcagccttt
    16441 ggacgttacg gggaaggcta cgtccgccta tcttatgcag ccagcatgga gactatcaaa
    16501 gaagccatga aacgacttga ggagtacatg agagaagcat gattcagtct atcacgagtc
    16561 aaggcttggt gctttacaat cgcaattttc gtgaggatga caagctcgtc aaaattttta
    16621 cagagcaggt tggcaaatgc atgttttttg tcaaacacgc tggtcagtct aagctggcgc
    16681 ctgttattca gcccttggtg ctggcacgat ttctcttgcg aatcaatgat gacggactca
    16741 gttacatcga agactatcat gaggtcatga cttttcccaa gattaatagt gacctctttg
    16801 tcatggccta tgcgacctat gtggcagctc ttgcagatgc tagtttgcag gacaatcagc
    16861 aggatgctcc cttgtttgct tttttgcaaa agactttgga gttgatggaa gcaggcttgg
    16921 attatcaggt tttgaccaat atttttgaaa ttcaaatttt gactcgattt ggaatcagcc
    16981 tcaattttaa tgagtgtgtc ttctgccatc gggttggtca ggcttttgac ttttctttca
    17041 aatatggagc ctgcctctgt ccagagcatt atcatgagga taagagacgt tgtcatctca
    17101 atcccaatat cccctatctg ctcaatcaat ttcaagctat tgattttgag actttggaga
    17161 ccatttcgct caagcctgga atcaagcaag agctacgcca atttatggat caattatatg
    17221 aagagtacgt tgggattcac ctaaaatcaa agaaatttat tgattcccta gcagactggg
    17281 gacaattact aaaagaggaa aagaaatgaa aaaaatcgca gtagatgcca tggggggcga
    17341 ttacgcacct caggccattg ttgagggtgt caatcaagcc ctatctgact tttcagatat
    17401 cgaggttcaa ctttacggag atgaagctaa aatcaagcaa tatctgacag cgacagagcg
    17461 cgtcagcatt atccatacgg atgagaagat tgattcggat gatgaaccta cgagagctat
    17521 taggaataag aaaaatgcca gtatggtatt ggcagccaag gctgtcaaag atggtgaagc
    17581 agacgctgtc ctttcggctg ggaatacagg tgccttgttg gcagcaggat tcttcatcgt
    17641 gggtcgtatc aagaatatcg accgtcctgg actcatgtct accttgccta ccgttgatgg
    17701 aaaaggtttt gacatgctag accttggtgc caatgcagaa aatacagccc agcacctcca
    17761 tcaatatgcg gttctaggtt ccttctatgc taaaaatgtc cgtggcattg cgcaaccacg
    17821 cgttggtttg ctcaacaacg gaacagagag tagcaagggc gacccgcttc gtaaggaaac
    17881 ttatgaatta ctggcggctg atgaaagttt gaactttatc ggaaacgtgg aagcgcgtga
    17941 tttgatgaat ggcgttgcag atgttgttgt ggcagatggt ttcacgggaa acgctgtgct
    18001 caaatccatc gaagggacag ctatgggaat catgggcttg ctcaagacag ctattacagg
    18061 tggtggtctt cgagcgaaac taggtgccct ccttctcaag gacagcctca gaggtttgaa
    18121 aaaacagctc aattattcag atgttggtgg agcggtcttg tttggtgtta aggcacctgt
    18181 tgtcaagact catggctcaa gcgatgccaa ggctgtttat agtacgattc gccagattcg
    18241 taccatgcta gaaacagacg tagttgccca gactgcgcgt gaattttcag gagaataaaa
    18301 gagatgacag aaaaagaaat ttttgaccgt attgtgacca ttatccaaga gcgacaggga
    18361 gaggactttg tcgtgacaga atccttgagt ctgaaagacg atttggatgc ggattctgtt
    18421 gacttgatgg agtttatctt gaccctggaa gatgaattta gtatcgaaat cagcgatgaa
    18481 gaaattgacc aactccaaaa cgtaggagat gtggttaaaa tcattcaagg aaaatagcaa
    18541 tcggagttcc aagtcaacgg aagtagatgg tttttagaaa tgagaaatat cggacaagct
    18601 ggtaaaatct tggctgacag tggttatcaa gggctcatga agatatatcc tcaagcacaa
    18661 actccacgta aatccagcaa actcaagccg ctaacagttg aagataaagc ctgtaatcat
    18721 gcgctatcta aggagagaag caaggttgag aatatctttg ccaaagtaaa aacgtttaaa
    18781 atgttttcaa caacctatcg aaatcatcgt aaacgcttcg gattacgaat gaatttgatt
    18841 gctggtatta tcaatcatga actaggattc tagttttgca ggaagtctaa tagtaaaaaa
    18901 gtgattagaa aacatctttt ttaaaaatag agatgatttt gaaacaaaaa agctaattca
    18961 agacgtttcg atgccaattc aagatttgga tgaaaaaaat taatagatac tgttatacta
    19021 aacttgtcaa gtttgtaaca agacaaatat taaaaataaa aaagaggtat tcgttatgaa
    19081 tacaaaaacg atgtcacaat ttgaaattat ggatactgag atgcttgctt gcgttgaagg
    19141 tggcggatgc aattggggag attttgccaa agcaggtgtt ggaggaggag cagtacgagg
    19201 tcttcagcta ggaattaaaa caagaacatg gcaaggtgca gcaactggtg ctgcgggagg
    19261 agctatactt ggaggtgtgg cctatgcagc gacatgttgg tggtaattat ggattttaaa
    19321 agttttatta ttggtttagt agttggtata tttggtcctt atatggatga tttaattaga
    19381 aaaaaatttt taaagtcttc ggagaagaaa acagaaaaat ctgttaaaaa ataatcaaaa
    19441 ctataaatga tgaatctgaa tcaaaattat tttgcgcatg taaagaggag tcttatagta
    19501 acgagtcaaa aaaggagtaa ctatgaatcg taatttagaa cggtgttatc tattctgact
    19561 aggaatagat cataccagag gtagcttaga aatagcaggg acattagaaa ttgaagtaat
    19621 aaataggatg tcgtaagtgt tactatcaat gatttatttg tttcaagctt gcctagggtg
    19681 acagtaaaaa atcaatttcc tttcaatagc atatttttag tgggcaggac tcttgttctg
    19741 cctatttttt tatccaaaaa gtgcagttgg gagggagata ggctcatttg ggaaggaagt
    19801 ccagtttttg tttagtgatt ggggtaagat agttgttatc agatgagttt atactcttcg
    19861 aaaatcaaat tcaaaccacg tcaacgtcgc cttgccgtat atatgtgact gacttcgtca
    19921 gtcctatcta caacctcaaa acagtgtttt gagcagcctg cggctagttt cctagtttgc
    19981 tctttgattt tcattgagta ttagggaaaa ggagatgaat atgaaatttg ggaaacgtca
    20041 ctatcgtccg caagtggatc agatggactg cggtgtagct tcattagcca tggtttttgg
    20101 ctactatggt agttattatt ttttggctca cttgcgagaa ttggctaaga cgaccatgga
    20161 tgggacgacg gctttgggct tggtcaaggt ggcagaggag attggttttg agacgcgagc
    20221 cattaaggcg gatatgacgc tttttgactt gccggatttg acttttcctt ttgttgccca
    20281 tgtgcttaag gaagggaaat tgctccacta ctatgtggtg actgggcagg ataaggatag
    20341 cattcatatt gccgatccag atcccggggt gaagttgact aaactgccac gtgagcgttt
    20401 tgaggaagaa tggacaggag tgactctttt tatggcacct agtccagact ataagcctta
    20461 taaggaacaa aaaaatggtc tgctctcttt tatccctata ttagtgaagc agcgtggctt
    20521 gattgccaat atcgttttgg caacactctt ggtaaccggg attaacattg tgggttctta
    20581 ttatctgcag tctatcattg atacctatgt gccagatcag atgcgttcga cactagggat
    20641 tatttctatt gggctagtca tcgtctacat cctccagcaa atcttgtctt acgctcagga
    20701 gtatctcttg cttgttttgg ggcaacgctt gtcgattgac gtgattttgt cctatatcaa
    20761 gcatgttttt cacctcccta tgtccttctt tgcgacacgc aggacagggg agatcgtgtc
    20821 tcgttttaca gatgctaaca gtatcatcga tgcgctggct tcgaccatcc tttcgatttt
    20881 cctagatgtg tcaacggttg tcattatttc ccttgttcta ttttcacaaa ataccaatct
    20941 ctttttcatg actttattgg cgcttcctat ctacacagtg attatctttg cctttatgaa
    21001 gccgtttgaa aagatgaatc gggataccat ggaagccaat gcggttctgt cttcttctat
    21061 cattgaggac atcaacggta ttgagactat caagtccttg accagtgaaa gtcagcgtta
    21121 ccaaaaaatt gacaaggaat ttgtggatta tctgaagaaa tcctttacct atagtcgagc
    21181 agagagtcag caaaaggctc tgaaaaaggt tgcccatctc ttgcttaatg tcggcattct
    21241 ctggatgggg gctgttctgg tcatggatgg caagatgagt ttggggcagt tgattaccta
    21301 taataccttg ctggtttact ttaccaatcc tttggaaaat atcatcaatc tgcaaaccaa
    21361 gcttcagaca gcgcaggttg ccaataaccg tctaaatgaa gtgtatctag tagcttctga
    21421 gtttgaggag aagaaaacag ttgaggattt gagcttgatg aagggagata tgaccttcaa
    21481 gcaggttcat tacaagtatg gctatggtcg agacgtcttg tcggatatca atttaaccgt
    21541 tccccaaggg tctaaggtgg cttttgtggg gatttcaggg tcaggtaaga cgactttggc
    21601 caagatgatg gttaattttt acgacccaag tcaaggggag attagtctgg gtggtgtcaa
    21661 tctcaatcag attgataaaa aagccctgcg ccagtacatc aactatctgc ctcaacagcc
    21721 ctatgtcttt aacggaacga ttttggagaa tcttcttttg ggagccaagg aggggacgac
    21781 acaggaagat atcttacggg cggtcgaatt ggcagagatt cgagaggata tcgagcgcat
    21841 gccactgaat tatcagacag aattgacttc ggatggggca gggatttcag gtggtcaacg
    21901 tcagagaatc gctttggcgc gtgctctctt gacagatgcg ccggtcttga ttttggatga
    21961 ggcgactagc agtttggata ttttgacaga gaagcggatt gtcgataatc tcatggcttt
    22021 ggacaagacc ttgattttca ttgctcaccg cttgactatt gctgagcgga cagagaaggt
    22081 agttgtcttg gatcagggca agattgtcga agaaggaaag catgctgatt tgcttgcaca
    22141 gggtggcttt tacgcccatt tggtcaatag ctagaaagag gagaggatga aaccagaatt
    22201 tttagaaagt gcggagtttt ataatcgtcg ttaccataat ttttccagta gtgtgattgt
    22261 acccatggcc cttctgcttg tgtttttact tggctttgca actgttgcag agaaggagat
    22321 gagtttgtcc actagagcta ctgtcgaacc tagtcgtatc cttgcaaata tccagtcaac
    22381 tagcaacaat cgtattcttg tcaatcattt ggaagaaaat aagctggtta agaaggggga
    22441 tcttttggtt caataccaag aaggggcaga gggtgtccaa gcggagtcct atgccagtca
    22501 gttggacatg ctaaaggatc aaaaaaagca attggagtat ctgcaaaaga gcctgcaaga
    22561 aggggagaac cactttccag aggaggataa gtttggctac caagccacct ttcgcgacta
    22621 catcagtcaa gcaggcagtc ttagggctag tacatcgcaa caaaatgaga ccatcgcgtc
    22681 ccagaatgca gcagctagcc aaacccaagc cgaaatcggc aacctcatca gtcaaacaga
    22741 ggctaaaatt cgcgattacc agacagctaa gtcagctatt gaaacaggtg cttccttggc
    22801 cggtcagaat ctagcctact ctctttacca gtcctacaag tctcagggcg aggaaaatcc
    22861 ccaaactaag gttcaggcag ttgcacaggt tgaagcacag atttctcagt tagaatctag
    22921 tcttgctact taccgtgtcc agtatgcagg ttcaggtacc cagcaagcct atgcgtcagg
    22981 gttaagcagt caattggaat cccttaaatc ccaacacttg gcaaaggttg gtcaggaatt
    23041 gacccttcta gcccagaaaa ttttggaggc agagtcaggt aagaaggtac agggaaatct
    23101 tttagacaag gggaaagtta cggcgagtga ggatggggtg cttcatctta atcctgagac
    23161 cagtgattct agcatggttg cagaaggtgc cctactagcc caactttatc catctttgga
    23221 aagagaaggg aaagccaaac tcacagctta tctaagttca aaatatgtag caagaatcaa
    23281 ggtcggtgat tctgttcgct atactacgac tcatgatgcc gggaatcaac ttttcctaga
    23341 ttctactatt acaagtattg atgcgacagc tactaagact gagaaaggga atttctttaa
    23401 aatcgaggcg gagactaatc taacttcgga gcaggctgaa aaacttaggt acggggtgga
    23461 aggccgcttg cagatgatta cgggcaagaa aagttaccta cgttattatt tggatcaatt
    23521 tttgaacaaa gagtaatgtt cgtgttttta gagttaaata atttttaaac tgtgagaaag
    23581 attcttcttg cagttttttc tttacaattt ttgaaaaaca tctactattt attcggttaa
    23641 attcttgtgt tttttggttt tttgtggtaa aatgtgctca agtaatacga aaggcgaact
    23701 ttaaaatgtc aaaacaattg atctattcgg gaaaagctaa agatatctat acaactgagg
    23761 atgaaaatct tattatttca acttacaagg accaggcgac tgctttcaac ggtgtcaaga
    23821 aggagcagat tgcaggtaag ggagtcttga ataatcagat ctcatctttt atttttgaga
    23881 aattaaatgt ggctggtgtg gcgactcact ttgtggagaa actttcagac acggaacaac
    23941 tcaataaaaa ggttaagatt attcctttgg aagtcgtgct ccgcaactat actgctggtt
    24001 ccttttcaaa acgttttggt gtggatgagg gaatcgcctt ggagactccg attgtcgaat
    24061 tttactacaa aaatgatgat ttggatgatc catttatcaa tgatgagcat gtgaaattcc
    24121 tacagattgc gggtgaccag cagattgcct acttgaagga agaaacgcgt cgtatcaatg
    24181 aactattgaa agtctggttt gctgagattg ggcttaaatt gattgacttt aagctagagt
    24241 tcggttttga caaggatggc aagattatct tggcagacga attttcacca gataactgcc
    24301 gcttgtggga cgctgatggc aaccacatgg ataaggatgt tttccgtaga ggattgggag
    24361 aactaaccga cgtttatgag attgtttggg aaaagttgca ggaattgaaa taatctgttt
    24421 gcaacggaaa accttcgtct ctcaactaaa aggactcagg ctgaaaaggt cccccagacc
    24481 ttttcactct gtagagaact aggtgaacta acagatgttt acgaaattgt ctgggaaaag
    24541 ttgcagggtt taaaataaca acctcaaggc tgtttgggaa tattgcaaga gctgaaataa
    24601 aggaataaga attgatggat aaacgtattt ttgttgaaaa aaaggctgat tttcaggtca
    24661 agtcagagag tttggttaga gagctccagc acaacttggg actgtcaagc ttgaaaagta
    24721 ttcgtattgt gcaagtatat gatgtatttg acttggctga ggacttgttt gcacctgcag
    24781 agaagcacat tttctctgag cagggaaccg accatgtttt agatgaagta tctgtgcagg
    24841 cggatcttgc taactatgct ttctttgcca ttgaaagtct gccagggcag tttgaccagc
    24901 gtgcagcttc gtcacaggaa gccttgcttt tgttgggaag ttcgagtgac gtgacagtca
    24961 acacagccca actttacttg gtgaataaag atattgatgc gactgagttg gaagctgtca
    25021 aaaactacct gctcaatcca gttgattctc gtttcaagga tatcacgaca gggattgcca
    25081 agcaggagtt ttcagagtca gacaagacca ttccaaaatt gactttcttt gaaagctata
    25141 cagcagaaga ctttgctcgc tacaaggccg agcaagggat ggccatggaa gtggatgatt
    25201 tgctctttat ccaagactac tttaagtcaa tcgggcgcgt gccaactgag actgaactca
    25261 aggttttgga cacttactgg tctgaccact gccgtcatac gacttttgag acagagttga
    25321 aacacatcga cttttcagct tctaaatttc aaaagcaatt gcagtcaacc tatgacaagt
    25381 atattgccat gcgcgaggag ttaggtcggt ctgaaaaacc acaaaccttg atggatatgg
    25441 cgactatttt cggtcgttat gagcgtgcta acggacgatt ggatgatatg gaagtctctg
    25501 acgaaatcaa tgcctgctca gttgaaattg aagtggatgt tgatggtgtc aaggaacctt
    25561 ggctcctcat gtttaaaaat gaaacccaca accatccaac agaaattgag ccatttggtg
    25621 gagcggctac ctgtatcggt ggagctattc gtgatccgtt gtcaggccgt tcctatgttt
    25681 accaagccat gcgtatttca ggtgctggtg atattacagc accgatttcg gaaactcgtg
    25741 ctgggaaatt gccacaacaa gtcatttcta aaacagcagc tcatggttat tcttcatatg
    25801 gtaaccagat tgggcttgcc acaacctacg ttcgtgaata cttccaccca ggctttgtag
    25861 ctaaacgtat ggaacttggt gccgttgttg gtgcggctcc caagggcaat gttgtccgtg
    25921 aaaaacctga agcaggtgat gtgatcatcc ttctcggagg caaaacaggt cgtgatggtg
    25981 tcggtggtgc gacgggctct tctaaggttc aaacagttga gtctgtagag actgctggtg
    26041 ctgaggttca aaaaggaaat gccatcgaag aacgcaagat tcagcgcctc ttccgtaatg
    26101 gcaatgtcac tcgtctgatc aagaagtcca atgactttgg ggcaggcggc gtctgtgtgg
    26161 ctatcggtga attggcagac ggtcttgaaa tcgacctcaa caaggtgcct cttaaatacc
    26221 agggcttgaa tggtacagaa attgccatct ctgaatcaca agaacggatg gcggtcgtgg
    26281 ttcgtcctga agatgtggat accttcgttg ccgaatgtaa caaagaaaat attgatgctg
    26341 ttgtggtggc gacagtaact gaaaaaccaa atcttgtcat gcactggaat ggtgagacaa
    26401 tcgttgactt ggagcgtcgt ttccttgaca ccaatggtgt gcgcgtggtt gtcgatgcca
    26461 aagttgtgga caaggatgtc aaactcccag aagagcgtca aacatctgct gaaacactgg
    26521 aatcagatac ccttacggtt ctatctgacc tcaaccatgc aagtcaaaaa ggattacaga
    26581 ctatctttga ctgctctgtt ggacgctcaa cggttaatca cccacttggt ggtcgttacc
    26641 aactcacacc aactgaggca tctgtgcaga aattgccagt tcaacacggt gtgactcata
    26701 ctgcgtcggt cattgctcaa ggtttcaacc catatgtagc tgaatggtct ccataccacg
    26761 gtgctgctta tgcggttatc gaagcaactg ctcgtttggt ggctgctggt gccaactggt
    26821 ctaaggctcg tttctcttac caagaatatt tcgagcggat ggacaagcaa gcagagcgtt
    26881 tcggtcagcc agtagctgct cttctaggtt ctattgaagc acaaattcag cttggcttgc
    26941 catctatcgg tggtaaggac tccatgtctg gtacctttga agaattgacc gttccgccaa
    27001 ccttggttgc ctttggggtg acgacggcag atagccgtaa ggtgctctct ccagaattta
    27061 aagctgttgg ggaaaatatc tactacatcc caggtcaagc cctctctgca gagattgatt
    27121 ttgacttgat taagaaaaat tttgctcagt ttgaagcaag ccaagctgac cataaagtga
    27181 cgtctgcatc agctgtcaaa tacggtggtg tagttgaaag tttggctctt gctacctttg
    27241 gaaactatat tggtgcagag gtgaccttgc ctgaacttaa aacagctttg acagctcaat
    27301 taggcggctt tgtcttcaca tctcctgaag aaattgctgg agtagagaag attggacaaa
    27361 cgaaagcaga ctttacactg actgtcaacg gtgtgaagct agatggacac aagcttgaca
    27421 gtgcatttca agggacattg gaagaagttt acccaacaga atttacccaa gcgaaagaac
    27481 tagaagaagt accagctgtg gcatcagatg ttgtgattaa agccaaagaa aaggttgaaa
    27541 aacctgtggt ttacatccca gtctttccag gaaccaactc agaatatgat tcagctaagg
    27601 ccttcgaaaa agaaggtgca gaggtcaatt tggtgccatt cgtgaccttg aatgaagaag
    27661 ctattgtcaa gtcagttgaa actatggttg acaatatcga caagactaat attctcttct
    27721 ttgccggtgg attctcggct gcggatgaac cagatggttc agctaagttt atcgtcaata
    27781 tcctgcttaa tgaaaaagtg cgtgtggcta ttgatagctt tatcgcccgt ggtggcttga
    27841 ttatcggtat ttgtaatgga ttccaagcct tagtcaaatc gggtctccta ccatacggaa
    27901 actttgaaga tgctaacagt actagtccaa ccctcttcta caatgatgcc aaccaacacg
    27961 tggccaagat ggtggaaact cgtattgcca ataccaactc accatggttg gctggtgtgc
    28021 aagtgggcga tatccacgct attcctgttt cgcacggtga agggaagttt gtcgtgacgg
    28081 ctgaggaatt tgcagagctc cgtgacaatg gacaaatttt cagccaatac gttgacttta
    28141 acggtaaacc aagtatggat tctaagtaca atccgaatgg ttctgtccat gccatcgaag
    28201 gaattaccag caagaatggt caaatcatcg gtaagatggg ccactcagaa cgttatgagg
    28261 atggtctttt ccaaaatatc ccaggcaata aagaccaaca cctgttcgca tcagcggtta
    28321 aacatttcac tggaaaataa gacttacaga ttttctaata gatagtatca gtaatgtaaa
    28381 agtcatgtaa atctagctct tgatgattac aaatgaaaat taggtataaa aaatgacata
    28441 cgaagtaaaa tctcttaatg aagaatgtgg tgttttcggt atttggggac atccagatgc
    28501 tgctaagttg acctattttg gactccacag tcttcaacac cgtggtcagg agggggcagg
    28561 aatcctctcc aatgatcaag gacaactgaa gcgccatcgt gacatggggc ttttatcaga
    28621 agttttcaga aatccagcca atttggataa attgacagga gctggtgcga ttgggcatgt
    28681 gcgttatgcg actgctggcg aagcttctgt tgataacatc caacccttcc tcttccgttt
    28741 tcacgatatg cagtttggtt tggctcataa tggaaatctg accaatgcag cctctctcaa
    28801 gaaagaactg gaacaaagag gagcaatttt cagcgcgact tcggactctg aaatcttggc
    28861 tcacctcatt cgtcgcagtc ataatcctag cctgatgggc aaaatcaagg aagcgctcag
    28921 ccttgtcaaa ggtggttttg cctatatctt gctgtttgag gacaagttga ttgcggctct
    28981 tgaccctaat ggctttcgtc cgctttctat cgggaaaatg gccaacggag cggtggttgt
    29041 ttcctctgaa acctgtgctt ttgaggtcat tggtgtcgag tggatttgtg atttgaagcc
    29101 aggtgagatt gtgatcattg atgacgaggg cattcagtat gacagctata cagatgatac
    29161 ccagttggcg atttgttcta tggagtatat ctactttgcc cgccctgatt ctaatatcca
    29221 cggtgtcaat gtccatacgg cacgtaagag aatgggagcg caattggcgc gagaatttaa
    29281 gcatgaggca gatattgtag ttggtgtgcc caattcttcc ctaagcgcgg ctatgggatt
    29341 tgcggaagaa tcaggcttac caaatgaaat gggtctgatc aaaaaccaat acacccagcg
    29401 aacttttatc caaccgactc aagaattgcg ggagcaagga gtgcggatga aactgtctgc
    29461 tgtttcgggt gttgtcaaag gcaaacgtgt ggtcatggtg gatgattcca ttgtacgtgg
    29521 aacaacctct cgtcgtatcg ttcagctctt gaaagaagcg ggtgcgactg aggttcacgt
    29581 tgccattgga agtcctgcac tagcgtatcc atgtttctac gggattgata tccagacccg
    29641 tcaggagctg attgcagcca atcatacggt cgaagaaact cgccaaatca ttggtgcgga
    29701 cagtctgact tatctttcaa ttgatggctt gattgagtcg attggtatcg aaacagatgc
    29761 gccgaacggt ggtctctgtg tcgcttactt tgacggtgac tacccaacgc ctctctatga
    29821 ctacgaagaa gactatcgta gaagtttgga agaaaagacc agtttttaca agtaggcgac
    29881 agattctcca ttaaagaaaa ggaaaaaaca aatgacaaat aaaaatgcat atgcctcacg
    29941 tctcactact gactaaaggc ttaagcattt agtcagtaga cgctttgtcc tataggatca
    30001 aagctagagc cctgactagt atttttagat aaaaagatgg tttatctaaa aatacgtcgc
    30061 agtctttctc aaaaaaagaa aaggaaaaat aaaatggcaa ataaaaatgc gtacgctcaa
    30121 tctggtgtgg atgttgaagc gggttatgaa gttgttgaac ggattaaaaa gcacgtggct
    30181 cgtacggagc gtgcaggtgt catgggagct cttggtggct ttggtggtat gtttgacctt
    30241 tccaagactg gggttaaaga acccgtcttg atttcaggga ctgacggtgt cggaaccaag
    30301 ctcatgttgg ctatcaagta cgacaagcac gataccatcg ggcaggactg tgtggccatg
    30361 tgtgtcaacg acatcattgc tgcaggtgcg gaacccctct attttctcga ctacgtagcg
    30421 acagggaaga atgaaccagc taagctagaa caagtggttg ctggtgtggc agaaggttgt
    30481 gtgcaggctg gtgctgccct catcgctggg gaaacggctg aaatgccggg catgtacggc
    30541 gaagacgact atgacttggc tggttttgcg gtcggtgtgg ctgaaaaatc tcaaatcatt
    30601 gacggttcaa aggtggtaga gggagatgtt cttctcggac ttgcttcaag tgggattcac
    30661 tcaaatggtt actctttggt tcgtcgtgtc tttgcggatt acacaggtga ggaagtccta
    30721 ccagaattgg aaggcaagaa acttaaggaa gttctacttg agccgactcg tatctatgtc
    30781 aaggctgtct tgccgctcat caaagaagag ttggtcaacg gcattgccca catcacaggt
    30841 ggtggcttta tcgaaaatgt ccctcgtatg tttgcagatg acctagctgc tgaaattgat
    30901 gaaagcaaag ttccagtgct tccaattttc aaagcccttg aaaaatatgg tcagattaaa
    30961 cacgaagaaa tgtttgaaat cttcaatatg ggtgtgggac ttatgttggc ggtcagccct
    31021 gaaaatgtag agcgtgtaaa agaattgttg gatgaagcag tctatgaaat tggtcgcatc
    31081 gtcaagaaag aaaacgaaag tgtcattatc aaatgaaaaa aatagcggtt tttgcctctg
    31141 gtaatggctc aaattttcag gtgattgccg aagaatttcc agtggagttt gtcttttcag
    31201 accatcgtga tgcctatgtg cttgagcgtg caaagcagct cggcgttctg tcctatgctt
    31261 ttgaactcaa ggagtttgag agcaagacag actacgaagc agcccttgtc gaactcttgg
    31321 aagaacacca gattgacttg gtttgcctag caggctacat gaaaatcgtt ggaccaacct
    31381 tattgtcggc ttatgaaggt cggattgtca acattcatcc agcctacttg ccagaatttc
    31441 caggagctca tgggattgag gatgcttgga atgctggcgt gggtcagtct ggtgtgacca
    31501 ttcactgggt ggattcgggt gtggatacag gccaggtcat caaacaggtt cgtgtgccac
    31561 gactagctga tgataccatt gacagatttg aagctcgcat ccatgaagca gagtacaggt
    31621 tgtatccgga agtagtgaag gctctattta cagattgact ttttgatgat tcatatgata
    31681 tctttgattt taaattggag tcagtgtttg ttgaagacgg cttcaaacgg aggtatttgt
    31741 aatgttagaa tctaaaaaaa caactcgata tgtattttat gtctatctga tgttattaac
    31801 ttggggaatc ttatttaagt ttgaaacaaa tcctgaattt atagcatttt tcttagctcc
    31861 aaggtatatc aattggattc cattttcaga accactaata gtcgatggaa aaattgtttt
    31921 tgctgaaatg ttatttaatc tgatttcctt tattccatta ggtgtttgtt tccctttgat
    31981 aaaaactaat ttatctagtt taagaatagt cgggacaggt ttcttgatta gtttattgtt
    32041 tgagtgctta cagtatattt tagcaatagg tataacagat ataacggatt tgactttaaa
    32101 tacgctaggt gtctgtgtag gcttactgat ttatcaaatt tttataagag tgttcaaatc
    32161 acagactaga aaatggatca atatcttagg tatgcttagc cttggttttg cttatcttgt
    32221 tttactgtta ctgcatttaa ttggtgttta actaatgatt aaaaaggaga atataatgac
    32281 taaacgcgtc ttaatcagcg tctcagacaa agcgggcatt gttgaatttg cccaagaact
    32341 aaaaaaactt ggttgggaga ttatctcgac aggtggaact aaggttgccc ttgataatgc
    32401 tggggtggag accattgcga tcgatgatgt gacgggcttc ccagagatga tggatggccg
    32461 tgttaagact cttcatccaa atatccacgg gggtcttctc gctcgtcgtg atttggatag
    32521 ccacttggaa gcagccaatg agaaccaaat tgagcttatt gaccttgtag tggtcaacct
    32581 ttacccattt aaggaaacta tccttaaacc agatgtgact tatgctgatg cagttgaaaa
    32641 tatcgatatt ggtgggccgt ctatgcttcg ttcagcagcg aaaaatcatg ccagtgttac
    32701 agttgtggta gatcctgctg actacgctgt ggttttggac gaattggcag caaacggcga
    32761 aacctcttat gaaactcgcc aacgtttagc agccaaagta tttcgtcaca cagcggctta
    32821 tgacgccttg attgcagaat acttcacagc tcaagtgggt gaaagcaagc ctgaaaaact
    32881 cactttgact tatgacctca agcaaccaat gcgttacggt gagaatcctc aacaagacgc
    32941 ggacttttac cagaaagctt tgcctacaga ttactctatt gcttcagcca aacagctcaa
    33001 cgggaaagaa ttgtcattta ataatatccg tgatgcagat gctgctatcc gtatcatccg
    33061 tgacttcaaa gatagtccaa ccgttgtggc tctcaagcat atgaatccat gtggtatcgg
    33121 ccaggcggat gacatcgaga cggcttggga ttatgcttat gagtctgacc cagtgtctat
    33181 ctttggtggt atcgttgttc ttaaccgtga ggtggatgct gcgacagctg agaagatgca
    33241 cggcgttttc ctcgaaatca tcattgcacc aagctatacg gatgaagcgc tagctatttt
    33301 gatcaataaa aagaaaaact tgcgtatcct tgccttgcca tttaatgctc aagaggctag
    33361 cgaagtggaa gcagaataca caggtgtagt cggtggactt ctcgtgcaaa atcaagacgt
    33421 ggtcaaggaa agcccagctg actggcaagt ggtgaccaaa cgtcagccaa ccgagacaga
    33481 agcgactgct cttgagttcg cttggaaggc tatcaagtac gtcaaatcaa atggtattat
    33541 cgtgaccaac gatcacatga cacttggtgt tggtccaggt caaaccaacc gtgtggcttc
    33601 tgttcgcctt gccattgacc aagccaaaga tcgtctggac ggggcggtcc ttgcttcaga
    33661 tgccttcttc ccatttgcgg ataacgtgga agaaatcgcc aaagcaggaa ttaaggccat
    33721 catccagccc ggtggctctg tccgtgacca agaatccatc gaagcagcgg ataaatatgg
    33781 cttgactatg gtctttacag gtgtgagaca ttttagacat taagaagata aaagggaaga
    33841 aaacagtttc tttccttttt tggcttaaaa tgctaactga aacaagatta aaacgaactt
    33901 ttttgatata atgttggtaa ataattcgca aaagaggttg aggaatgaaa ctgcttgttg
    33961 tcggttctgg tggtcgtgag catgcgattg ctaaaaagtt acttgaatca aaagacgtgg
    34021 aaaaagtctt tgtagctcct gggaatgatg ggatgactct ggatggtttg gaattggtaa
    34081 atatctctat ttccgaacat tctaaattga ttgacttcgc aaagaccaat gatgttgctt
    34141 ggacctttat cggtccagat gatgcccttg ctgctggtat cgtggatgat tttaaccaag
    34201 ctggacttaa ggcctttggt ccgactaggg ctgcagcgga gctggagtgg tccaaggatt
    34261 tcgccaagga aatcatggtc aaatacggcg ttccgacagc aacatatggc acattttcag
    34321 atttcgagga agccaaggcc tatatcgaaa agcatggtgc gcctatcgta gtcaaggcgg
    34381 atggcttggc acttgggaag ggtgtcgtcg ttgctgagac ggttgagcaa gcggtcgaag
    34441 ccgctcatga gatgcttttg gacaataaat ttggtgactc aggtgcgcgc gtggttattg
    34501 aggaattcct tgaaggagag gaattttcac tctttgcctt tgtcaatggt gataagttct
    34561 acatcatgcc aacggctcag gaccacaaac gtgcctatga tggcgacaaa gggcctaaca
    34621 cgggtggtat gggtgcctat gcgccagtcc cacacttacc acagagtgta gttgatacag
    34681 cggttgacac cattgtcaag ccagttctag aaggggtgat taaagaaggt cgcccttatc
    34741 tgggagttct ttacgcaggg cttatcctga cagctgatgg accgaaagtc attgagttca
    34801 acgctcggtt cggagatcca gaaactcaga ttatcttgcc tcgcttgacc tctgactttg
    34861 ctcaaaatat cacagatatc ctggatagca aggagccaaa tatcatgtgg acggacaagg
    34921 gtgtgactct gggtgtggtt gtcgcatcca agggctaccc gctagactat gaaaggggcg
    34981 ttgagttgcc agcaaagaca gaaggcgatg tcatcaccta ctatgcaggg gctaagtttg
    35041 cggaaaatag cagagcactg ctctcaaacg gcggacgagt ttatatgctc gttaccacag
    35101 cagataccgt caaagaagcc caagccagca tctaccaaga actatcccaa caaaaaatag
    35161 aaggactctt ctaccgaaca gatatcggaa gcaaggcaat taagtaaaga tataagaata
    35221 acgcgccgta gtcgccaaac acgataatgg tcgtcgtggt gaaaagacca gaacagtgaa
    35281 tgttctggtc agggggaaac ttggagacct taggctcaaa gtttaggaat gaaaccgaag
    35341 gtttgcttcc gcctccatca cctaagacca ttatcaaaaa gaaaaataaa aattcacaaa
    35401 atacgttaat gatcgtatgg tttgcgagcg ttagcgagct aatatagaac aatcaccgcc
    35461 gttgtgaaag aacgattgga tgataatcca atcgttcagg gaaattggaa gaccttgggt
    35521 ttccaattta ggcatgagac acctttggtg gctgctgccg tccctcacaa gctaaggtga
    35581 ttgttgaaaa agaggaaaaa ggagaagaaa tgaaaccagt aatttccatc atcatgggct
    35641 caaaatccga ctgggcaacc atgcaaaaaa cagcagaagt cctagaccgc ttcggtgtag
    35701 cctacgaaaa gaaagttgtt tccgcacacc gtacaccaga cctcatgttc aaacatgcag
    35761 aagaagcccg tagtcgtggc atcaagatca tcatcgcagg tgctggtggc gcagcgcatt
    35821 tgccaggcat ggtagctgcc aaaacaaccc ttccagtcat tggtgtgcca gtcaagtctc
    35881 gtgctcttag tggagtggat tcactctatt ctatcgttca gatgccgggt ggggtgcctg
    35941 ttgcgaccat ggctatcggt gaagctggag cgactaacgc agctctcttt gccctccgtc
    36001 tcctctctgt agaagataag tccattgcgg atgcacttgc caactttgct gaagaacaag
    36061 gaaaaatcgc agaggagtcg tcaaatgagc tcatctaaaa caatcggaat tatcggtggc
    36121 ggtcaactgg gtcagatgat ggccatttct gctatctaca tgggccacaa ggttatcgcg
    36181 ctggatcctg cggcggattg cccggcctct cgcgtggcgg aaatcattgt ggcaccttat
    36241 aacgatgtgg acgccctccg tcagttggca gaccgttgcg atgtcctcac ttacgagttt
    36301 gaaaatgtcg acgctgacgg tttggatgcc gttatcaagg atggacaact ccctcaagga
    36361 acagatctgc tccgcatttc gcaaaatcgt atttttgaaa aggacttttt gtcaaacaag
    36421 gctcaagtca ctgtggcacc ctacaaggtc gtgacttcta gcctagactt ggcagatatc
    36481 gacttgtcga aaaactatgt cctcaagact gcgactggtg gctacgatgg tcatggacaa
    36541 aaggttattc gttcagaagc agacttggaa gcagcctatg cgctagcaga ctcagcagac
    36601 tgcgtcttgg aagaatttgt caactttgac cttgagattt ctgtcatcgt gtcaggaaat
    36661 ggcaaggagg tgacgttttt cccagttcag gaaaatatcc accgcaacaa tatcctgtct
    36721 aagaccatcg taccagcccg catttctgaa agtctagcag acaaggctaa agctatggca
    36781 gtgcgaatcg cagaacaact caacttgtct ggaactctct gtgtggaaat gtttgcgact
    36841 gatgatgacg ttattgtcaa tgaaatcgcc ccacgaccac ataactctgg gcactattct
    36901 attgaagcct gtgatttctc tcagtttgac acccatattc tcggtgttct cggagcacca
    36961 ttaccagtca tcaaactcca tgcgccagcc gttatgctta atgtcctcgg tcagcatgtc
    37021 gaggctgctg agcaatatgt gacagaaaat tcaagcgccc acctccacat gtatggtaaa
    37081 atagaagcga agcacaaccg caagatggga catgtgacct tgtttagtga tgtaccggat
    37141 agtgtggatg agcttgggga agggattgat ttttaggaca agtctatgat acaaattatc
    37201 gttaatacat ttattgaaaa ggataagact ggagcagttg ttgaagtgtt gtatgccagt
    37261 gctgaccaag ataaggtaca agctaaatat gaagaactag ctgcacaata ccccgaaaat
    37321 tatttagcta tctatgatgt accgctggat acggatttga atacactaga tcattacccg
    37381 tctgtgttta ttgaaaaaga ggagtttgag tagaaatctt ggtttaccta gatagcttat
    37441 tcccaacagc ttaagaagaa aggaaaaatt aacacatgat caaccgttac tctcgccctg
    37501 agatggcgaa tatttggagt gaagaaaata aataccgtgc ttggcttgag gtggaaatcc
    37561 tctctgacga ggcatgggct gagttggggg aaatccctaa ggaagatgtg gctttgattc
    37621 gcaagaaggc ggactttgac atcgaccgta ttttggaaat tgagcaggag acgcgccacg
    37681 atgtggtggc tttcacgcgt gcggtttctg agactcttgg tgaagagcgc aagtgggttc
    37741 actatgggtt aacttctacc gacgtggtgg atactgctta tggttacctc tacaagcagg
    37801 ccaacgacat catccgtcgt gaccttgaaa acttcactaa tatcatcgct gacaaggcca
    37861 aggagcacaa gttcaccatc atgatggggc gtactcatgg tgtgcacgct gagccgacaa
    37921 cctttggtct taaattggca acttggtaca gcgaaatgaa acgcaatatc gagcgtttcg
    37981 agcatgcagc tgctggtgta gaagctggta agatttctgg tgcggttggg aactttgcca
    38041 atatcccacc atttgtagag gagtatgtct gcgataaact tggcatccgt gcccaagaaa
    38101 tctctacaca agtccttcct cgtgaccttc acgctgagta ctttgcggtt cttgccagca
    38161 ttgcgacttc aatcgaacgt atggcgactg agattcgtgg tctacaaaaa tctgagcaac
    38221 gcgaagtaga agagttcttt gctaaagggc aaaaagggtc ttcagcaatg cctcacaaac
    38281 gcaacccaat cggttctgaa aatatgactg gtctggcgcg tgtcattcgt ggtcacatga
    38341 ttacggctta tgaaaacgtc gctctctggc acgaacgcga tatttctcac tcatcagctg
    38401 agcgtatcat cacaccagat acgaccattt tgattgacta catgctcaac cgttttggaa
    38461 atatcgtcaa gaacttgaca gtcttcccag aaaatatgat ccgaaacatg aactcgactt
    38521 ttggtcttat ctttagccaa cgggctatgt tgacattgat tgaaaaaggc atgacccgtg
    38581 agcaagccta tgacttggtg caaccaaaaa cagcctactc ttgggacaac caagtagact
    38641 ttaaaccact tcttgaggca gattcagaag taacatcacg tctcactcaa gaagaaatcg
    38701 atgaaatctt caacccagtt tattacacca aacgagtgga tgatatcttt gaacgtcttg
    38761 gactaggtga ttaattaaaa aataaacagc gagcttcaat ctcgctgttt attttttatc
    38821 gaaaagactt agtcttcttt tcttttagtg agtccatagg ctgctagtgt ggacatgagt
    38881 cctgcgacta ctagtcctgc agaatcgtga gttcctgttt caggaagttt tttctctgtt
    38941 accacaggag ctggatcttg aggaagagct ttgctttcct cagcaggagc agttgatgga
    39001 gctggttggc ttgggatttc tagttttggt ttttcttcag caatagcggc ttgtccgttt
    39061 tcatcgccta catgtgttac catagttccg acttcgacta tttgagtaac ggcttcctgt
    39121 gctacgacac tatttacaag tgttttcact tccttaccat cggcagaagt gctcacagag
    39181 tagaagttgc tacgatgtcc attgacgccc ttagtaatga cttgtgtttt tcctttgagt
    39241 aagagtggat tttcacgagt cactgtggta aatggaattt cttctttttg gatatccagt
    39301 ctaggtttta cctcagtagt tggtgcaaga ccactttcat cacccttgtg agttacagga
    39361 gcgccaactt caaccacttg gtttataact tctttggtta cctggctatc aaggactgtt
    39421 tctgttgttt ttccattttc agtgagtaca gagatgtaat gagttcgttc acctttgact
    39481 cctgctgtga taatattttc ctgaccagct gggaggttag gattttcttt cttgataact
    39541 tcaaatggaa tttcttcagt tcttgtgatg agttctggtc tggtttcaac attggcagcc
    39601 acttcatttt catctaggct tcctgaatga gttgcagctg gtttgaggcc ttgaagagcg
    39661 gcttttaggt tggctacaag tgtgtcaagc tcagcttgtt tattacggtt gaggttgtaa
    39721 tttagagctg ttttagctgc gtcaagggtc tcaagacttt ctttactata tccttctaag
    39781 tttgtaggaa ttttagctaa ttcttcgcgg agagcattat aattagcacg gaagtagtct
    39841 ttgttgtggt ctgcaaaggc agtcatgagt tcaaagattt cctcttcctt gtattcagcg
    39901 cttggtctat ctgcccagat tgaaagcata cttccgactg ttggaagatc tacttcagga
    39961 tatttggtag aagctagttg attgaatggt gtttttccag tattctcaat agctttcttg
    40021 aggaaaccac caccatcttc tggtttttga ccaagaatgt agtaccagtc accgttggta
    40081 ttcaagaatt tatagccttt gcttgctagg tattgaggtg atgcgaggtt atatccccac
    40141 cagcctttag accagtaaga aatcaagaca tctttgtcaa actgaacatc gtccttgtct
    40201 tcatagtaga agccatcgtt gaaggccatt ggttgaagcc ctctttcttt ggccatagct
    40261 gcgagggtgt tggcatattc ggcaaatttg ccatagagtt gataccactt gaggtagtac
    40321 cagccttggg cactagtcgc atcgttggcg tattcgtcag taccaaagtt gaaaatcttt
    40381 gttttacctg caaagaagtc catgtattta ccgatgaggg cttttacaaa gttcatcgct
    40441 tcttcgtttt tcaagtccat agttgttttt gaaactttat caaagtgggc ttgaggattt
    40501 ttaataccta atttttccat ggcaaccagc atagcatcca tgtgacctgg actgttaata
    40561 gctgggatga gaccgatgtc cttagattta gcgtattcaa ttagctctgt tacttctgcc
    40621 tgtgttagtg cagtaccgtt tggatcgtcg tagtaagctt tagttccttc gataatagct
    40681 tttttaacgt catcactagc ataggttttt ccgttggcag taatggtcat atcatcgagt
    40741 agaaagcgaa gtccgtcatt tcctagaagg agatggacat cagaatatcc gagctcactg
    40801 gccttgtcta cgatgcgttt gagctggttc agagtaaagt atttgcgtcc agcatcgatt
    40861 gagattacct tgtttttggc aagtttttca acctcacgtt tagcttcttc ttctttttga
    40921 gcttcaggcg tgagggtcaa gttgttgaca gtttcttgaa gtttagcaat ggcttgatca
    40981 atcgtatctt gttgggcacg gctaaggttg ctatcgagag agcgaatagc tttttcagct
    41041 tcttttacgg ccgtgacgct ttctgcagta taacggttca ggtcttttgg tacctcgtta
    41101 agtgcttgct ctgcagattc ataatcagct gcgaagtatt cagcgttggc atttgcaaaa
    41161 tgacgcatga gtttgaagag gcgtgatggt gaataacgtg cagatggagt gtcagcccaa
    41221 gcagctacca taccaccgat gattgggata tcagctcctt ctgtttttgg tacagaagtg
    41281 attggtgtgt ttttaatacc attgagcccc tgatcgagat tgtaccagcc ttggccatca
    41341 gcgtttcgtc caagaacgta gtaccaagca tcattggtat taaggatttg gtgacctttt
    41401 tcagctagta gtttagaaga agcgacatcg tagcctcccc aaccaccagt ccacatagaa
    41461 acgatgatgt ctttgtcaaa actaccaaag cttgtgtcgc tattgtagta gataccgtcg
    41521 ttaaaggcca ttggtttgag accgtgcgat tttacaatac gagcgaggtc attggcgtag
    41581 gcaataaatt tttcatagcc ttttacaggg tagccttcgt ttggatagta tttatcagct
    41641 tgaagcacac tccaaccttt agcatctgtc gcatcattgg catattcatc aagtccgatg
    41701 ttgaagattt cagtcttttt cgcgaaataa gcagcatact tgtcgataag ggcttttgta
    41761 aaagcgacag cttgttcgtt gtcaagatcg acagtacggg ctgatttctt cccaaaatag
    41821 ctaaagttag ggttttggat tcccaattct ttcatggcat tgagaatcgc atccatgtgt
    41881 ccaggactat ttactgtcgg aatgagaccg atacctttat ctttggcata gttaatcaga
    41941 tctgtcattt gactttctgt taagtgattg ccgtttggat cgttgtaata atcatttgta
    42001 cctttttcaa tggcgcgttt gacatcgtca ctggcatagg tcttgccgtt agctgtgatg
    42061 ctcatatcgt ccaacatgaa acggagtcca tcatttccga ctaataggtg taaatcagtg
    42121 tagccataat gtttcgcttt atcgatgatt tccttgagct gttctggtga gaaatattta
    42181 cgtccagcat caatagaaac aattttcttt ttcgctagtt tttcatttac agttgcagca
    42241 cgttcctttc ctgcctctgt ttccggtttg tcagcctctg ctttcgcttc atctttttta
    42301 gctggtttat ccttgtcagt cttgtctgta tttgactctt tagaatcaac ctctttcgct
    42361 tcttcctttt tagggctagc ttcttctgcc tttttattag cagtttcttt ttcagcagaa
    42421 gttggagtta ccacttctgc tttatcacta ggagttgaac taacttcctc ttgtggtttt
    42481 tcttctgttt ttggaagact agctacctta tcagtagctg gagtttctgt ttctacagtt
    42541 tttggagctt ctggttgaag ctctgcttta ggtgtttcct cagtccgatt ttcggatgat
    42601 tgaggggaat cagaaaccgt atggatggtc ggttggtttt ctgtagtagt aggagtaact
    42661 ccatcggctg caacagtctg tgcttggaag gcaaatccaa ttagaacaga agctgctcct
    42721 acagcgtatt tacgaataga aaaacgctgt tgtttttcat gtttcattgc aaaacctcct
    42781 gattgcattg ttatattgat agcgattata taaatcaacg cctttatttt atttcttata
    42841 ttaacgagag tcaagaggag atgacaaaaa actataataa gtataaaaaa atataaaatt
    42901 taaacttaag atttcagatt ggtcggaaaa aatgaatata tatatctagt ataatttttg
    42961 gttctatttc tataaaatat tccacaaatt atagaatctt ccaaaaatag gtaagcgcta
    43021 cctttttggt gtggtataat aagcatagaa aaagcccaag cgattagctc aggctttctt
    43081 cttagtgatc acggtcacat gagataaatt taatcttgta gtaatcagat cgtttgtaag
    43141 tttcactgta ttctaaaact tggccagttg attcgagttt ggtgatttta gtttgtagga
    43201 cagtagggaa ttgttcatcg actccgagga ctgaagccgc atgttctgga gttggaaaga
    43261 ctatttcgtt gatttcttca aagtgttcat cattcatgtg aatgtggtag tctaacttga
    43321 aacgattata gatagaacta tagtattcaa ggtttggata atttgcgttg atatattgtt
    43381 ctgggatgta ggatgtatgg tagatataaa cgacaccgtt tgattcgcgg atacgttcaa
    43441 tcttgtagta gaattgatcg ccgcgtagac ccaatttttc caagtaaaca agcttgtttc
    43501 cgcgttcaat tgaaagaaca gttaccttat catctttagc attgaagagt tcaatatctg
    43561 aaaactctac aagcttgtgt ttgcgcgcac gtgaaacgaa ggttcctttt ccttgttggc
    43621 ggacaatata gccatctttg gcaaggtcgt ttaaggcgcg aacaactgtg atagagctga
    43681 catcgtacat tgaaatgagt tctgcttcag tgtaaaattt atctccactg ctaaactgcc
    43741 cagagatgat tttatttttt aattcgtctt ttatgtattg atatttggga attgccatat
    43801 ttttacctct attttccttc tccatagaaa attttaccat aaaagcgaaa aaaatagtag
    43861 tcttttgaat aaaaaattag aataatagtt tgaaaaatta agcgatatag ggattgctca
    43921 tattttataa atgtattcta tacaaaatta ttttaggtcc tatattccga atttaaagag
    43981 cgtttgaaat gggtctaaaa atgtttgaaa ctaattgaat gtgtgtataa tagtaaaaat
    44041 gcagtaaata tcccgacaat ttctattgac aattcaaaca gattggttta taattaatat
    44101 aacaacaaat gaaagcgcaa actttcgcgg tcggaaggta gttttatgac acgatttgag
    44161 atacgagatg atttctatct cgatggaaaa tcatttaaga ttttatctgg tgccattcat
    44221 tattttaggg ttcctccaga ggattggtat cattcgctct ataacttgaa ggctcttggt
    44281 tttaatacgg tagagactta tgttgcttgg aatttacacg agcctcgtga aggtgagttt
    44341 cattttgacg gtgatctgga tttagagaaa tttctccaaa tagcgcagga tttgggtctc
    44401 tacgcaattg tgcgtccgtc tccatttatc tgtgcggaat gggaattcgg tggcttacca
    44461 gcttggctct tgaccaagaa catgcgaatt cgctcatccg acccagcata tatcgaggca
    44521 gttggtcgct actatgatca gttattgcca agactggttc ctcgtttgtt ggacaatggt
    44581 ggcaatattc tcatgatgca ggttgaaaat gagtatggtt cttacggaga agataaggct
    44641 tacctgagag cgattcgaca gctaatggaa gagtgtggcg taacctgtcc cctctttaca
    44701 tcagatggtc catggcgagc tactctgaaa gctggaacct taattgaaga ggacctcttt
    44761 gtaacaggaa actttggttc taaggcacct tacaactttt cgcagatgca ggaattcttt
    44821 gatgaacatg gtaagaaatg gccactcatg tgtatggagt tctgggatgg ttggtttaat
    44881 cgttggaaag aaccgattat cacacgggat cctaaggaat tggcagatgc agttcgagaa
    44941 gttttggaac aaggctccat caatctttac atgttccacg gtggtacaaa ctttggtttc
    45001 atgaatggtt gctcggctcg aggaactttg gacctgccac aagttacgtc ttatgattac
    45061 gatgcccttc tggatgaaga aggaaatcca actgctaaat atcttgcagt caagaagatg
    45121 atggcaacac atttttcaga gtatccgcag ttggaaccac tctacaaaga gagtatggag
    45181 ttggatgcta ttccactagt tgaaaaagtt tctttgtttg aaaccttaga tagcttgtca
    45241 agtcctgtag aaagtctcta tcctcaaaag atggaggagc tgggacaaag ttatggctac
    45301 ctactttatc gaacagaaac aaactgggat gcagaagaag aaagacttcg tatcattgat
    45361 ggtcgagata gggcccagct gtatgtcgat ggtcagtggg ttaaaactca atatcagaca
    45421 gagattgggg aagatatttt ttatcaaggt aaaaagaaag ggctatctag gttagatatc
    45481 ttgatagaaa atatggggcg tgtcaactat gggcataagt tcttagcgga tacgcaacgt
    45541 aagggaattc ggacaggggt ctgtaaggat ctgcatttct tactaaactg gaaacactat
    45601 ccactcccac tagacaatcc tgagaaaatt gatttttcaa aaggatggac tcaaggacaa
    45661 ccagcctttt acgcttatga ctttacagtc gaagagccaa aagatactta cctagacttg
    45721 tctgagtttg gtaagggggt tgcctttgtc aatgggcaga atctaggacg tttttggaac
    45781 gttggcccaa ctctctcact ttatatccct catagctatc tcaaggaagg tgccaaccgc
    45841 atcattatct ttgaaacaga aggtcaatat aaagaagaga ttcatttaac tcgtaaacct
    45901 acactaaaac atataaaggg ggaaaactta tgacaattgt aggatgccgt attgatggac
    45961 gtttgatcca cggacaagta gccaatcttt gggctggaaa actaaatgtt tcacgcatta
    46021 tggttgtaga cgacgaagtt gtcaacaacg atattgaaaa gagtggtttg aaacttgcga
    46081 caccaccagg tgtgaaattg agtattttgc cagttgagaa agctgcagcc aatattcttg
    46141 ctggcaaata cgatagccaa cgtctcttta tcgtggctcg taaaccagac cgcttccttg
    46201 gtttggtaga agcaggtgta ccacttgaaa cccttaatgt tgggaatatg tctcaaacac
    46261 cagaaactcg ttctattaca cgttctatca acgtagtaga caaggatgtg gaagacttcc
    46321 acaaactggc agaaaaaggt gttaaactta ctgctcagat ggttccaaat gatccaattt
    46381 cagacttttt gagcttatta aaataggaaa aaatttttta ggaggtcatt gttatgatac
    46441 aatggtggca aattttactt ctcactttgt actcagctta tcaaatctgt gatgagttga
    46501 cgatcgtttc atctgcaggt tcccctgtat ttgctggttt cattactggt ttaatcatgg
    46561 gagatgtgac tactggttta cttatcggtg gtaacttgca actgttcgtt cttggggttg
    46621 gtaccttcgg tggtgcttct cgtatcgacg caacttctgg tgcggttctt gcgacagcct
    46681 tctctgtttc acaaggaatt gatgcaccgc ttgcaattac tacaatcgct gtaccagtag
    46741 cagctctctt gacttacttc gacgttcttg gtcgtatgac tactaccttc ttcgctcacc
    46801 gtgtggatgc tgcaatcgaa cgctttgact ataaaggtat tgaacgcaac tacttgcttg
    46861 gtgcgattcc gtgggctcta tctcgtgccc ttccagtctt ctttgccctt gcttttggtg
    46921 gtgcctttgt acaatcagta gtagacttcg ttgaagccta caaatgggtt gcagatggct
    46981 tgacactcgc aggacgtatg cttccaggtc ttggatttgc aatcttgctt cgttaccttc
    47041 cagttaaacg taaccttcac taccttgcta tgggatttgg tttgacagct atgttgactg
    47101 ttctttactc atatgtaaca ggtcttggtg gcgctgttgc tggtatcgta ggtactcttc
    47161 ctgctgaagt tgctgaaaaa attggtttcg tgaacaactt caaaggtttg tctatgattg
    47221 gtatttctat cgtaggtatt ttccttgcag tgcttcactt caaaaatagc caaaaagtag
    47281 ctgtagcagc accttctaca ccatcagaaa gtggggaaat cgaagatgac gaattctaat
    47341 tacaaactta caaaagaaga ttttaatcaa atcaacaaac gtagcttgtt tactttccaa
    47401 ttaggttgga actacgaacg tatgcaagct tctggttacc tttacatgat cttgcctcag
    47461 ttgcgtaaaa tgtatggtga tggaactcct gaattgaaag aaatgatgaa agttcatact
    47521 caattcttca atacttcacc attcttccat accattatcg ctggttttga ccttgccatg
    47581 gaagaaaaag atggtgtagg ttcaaaagac gctgttaacg gtatcaagac aggtttgatg
    47641 ggaccattcg ctcctcttgg ggatacaatc tttggttcac ttgtacctgc tatcatgggg
    47701 tcagtcgcag caactatggc tatcgctggc caaccttggg ggatcttcct ttggattgca
    47761 gttgcagtag cgtatgacat cttccgttgg aaacagttgg aatttgctta caaagaaggg
    47821 gttaacctta tcaacaacat gcaaagtacc ttgacagctt tgattgacgc tgcatctgta
    47881 cttggtgtct tcatgatggg tgctcttgta gcaacagtga ttaactttga aatttcttac
    47941 aagttgccaa tcggtgaaaa gatgattgat ttccaagaca tcttgaacca aatcttccca
    48001 cgtttgcttc cagcaatctt tactgccttt atcttctggt tgcttggtaa aaaaggtatg
    48061 aactctacta aagctatcgg tattattatc gtacttgctt tggctctttc tgcccttggt
    48121 cactttgcac ttggaatgta attccttatg actaaatcat taattttggt gagccatggt
    48181 cgcttctgtg aggagcttag aggtagcaca gaaatgatta tgggcccaca agacaacatt
    48241 tacacagtag ctcttcttcc agaagatggc ccagaagaat ttactgctaa atttgaagct
    48301 gttattgaag gattggatga tttcctagtc tttgcggatc ttctcggtgg gacaccttgt
    48361 aatgtggtga gtcgcttgat catggaaggt cgtgatattg acctttacgc agggatgaat
    48421 cttccaatgg tgattgaatt tatcaatgcg agccttacag gcgcagatgc ggactacaag
    48481 agccgtgctg cagaaagcat tgtgaaagtt aatgacctgt tagcgggctt cgatgatgac
    48541 gaagatgaat aatactcttc gaaaatctct tcaaactacg tcaacgtcgc cttgccgtag
    48601 gtatatgtta ctgacttcgt cagtcttatc cggcaacctc aaagcggtgc tttgagcagc
    48661 ctgcggctag tttcctacag attttagttg gaactcgatt caattcatgt gacaacgtga
    48721 aaatcgttag agcattttat atagaatata catgggaatg gagcttactc ccattcccat
    48781 atttaataga aaaagaggaa ctcaatgcta cattatacaa aagaagactt gctcgaattg
    48841 ggtgcagaaa tcactacgcg tgaaatctac caacagcctg atgtatggag agaagctttt
    48901 gaattttatc aagcaaaacg tgaagaaatt gcagcctttc tacaagaaat cgctgataaa
    48961 catgactata ttaaggttat cttgacaggt gctgggactt ctgcttatgt gggagatacc
    49021 ttgctacctt actttaagga agtctatgac gaacgcaaat ggaatttcaa tgctattgcg
    49081 acaacagata tcgttgccaa accagcaacc tatttgaaaa aagatgtggc aactgtcctt
    49141 gtgtcttttg ctcgtagtgg gaactcgcct gaaagtgtgg cgactgttga tttggccaaa
    49201 tccttggtgg atgagcttta tcaagtgacg attacttgtg caacagatgg taaattggct
    49261 cttcaagctc acggtgatga ccgtaatctc ttgctcttgc aaccagctgt ctctaatgat
    49321 gctggatttg ccatgacttc tagctttacg tctatgatgt tgacagctct cttggtcttt
    49381 gatcctacag aatttgctgt taagtctgaa cgttttgaag ttgtatctag tcttgcccgt
    49441 aaagttttag acaaggtaga agatgtcaaa gagctcgttg atttagactt taaccgtgtc
    49501 atctatctag gcgctggtcc tttctttgga cttgctcatg aagctcagct caagattttg
    49561 gaattaactg ctggtcaagt tgcgaccatg tatgaaagcc cagttggctt ccgtcacggt
    49621 ccaaaatctc ttatcaacga caatacagtt gttttggtct ttggtacaac gacagcctac
    49681 actcgtaagt acgacttgga cttggttcgt gaagttgctg gtgaccagat tgctcgtcgt
    49741 gttgtgcttt tgagtgatca agcttttggt cttgaaaatg tcaaagaagt ggtccttggt
    49801 tgtggcggtg tcttgaatga tatttaccgt gtcttccctt acatcgttta tgcccaactc
    49861 tttgctctat tgacttcact caaggtagaa aataaaccag atacaccgtc tcctacaggt
    49921 acagtaaacc gtgtagtaca aggtgtcata attcacgaat atcaaaagta agacagtgtt
    49981 tatgaattct tgacaagagg atttgtaaat tatcagataa accatagatt gtcagtacgc
    50041 tttctatggt ttgtttgctt gagagaaata gtaaaaggag aacagaatga aagcatacac
    50101 agagcgtgta tttggaaatg ttgagggcga ggatgtcttg gcctatcgat ttgagacaga
    50161 cggtggctac caacttgagg ttatgactta tggcgcgacc atcttgcgct atgtcgcacc
    50221 tgacaaggct ggaaattttg ccaatgttat cttgggattt gatgactttg atagttatgt
    50281 aggcaatagt cccaagcatg gagcaagtgt aggtcctgta gcgggtcgta ttgcaggtgc
    50341 gacctttgag ctcaatggta agacctatga ccttgaggtt aataatgcta gcaactgtaa
    50401 tcacagtggt tcaactggtt gggattccag cttgtttgaa gttgaagaag taagcgatca
    50461 tggcttgact ctctacacag agcgtacaga tgggacagga gggttccctg gaaatctcaa
    50521 gatttggatc agttatcact tggaagaaac tggtgcctat gaaatcatct acaaggtaac
    50581 gaccgatcag gatacgctgg tcaatccaac caaccacagc tatttcaact tgtctggtga
    50641 tttcacgcag acgattgacc gtcatgtctt ccaactaaac acagagggca tttactcaat
    50701 cgctcctgac ggtgttcctg ccaaaactcc agaagccaac cgtgatgtgg tcaaacacat
    50761 ctacaatggt accttgttga aggatatctt tgcagaagaa gatgagcaaa tccagctggc
    50821 atcaggtttg gatcacccat ttgcccttcc tgcaggccat gacaatgctg gattccttta
    50881 tgaccaaaat tcaggtcgct tcctgctttt caagacagaa gctccttgct ttgtggtcta
    50941 cacagcaaac tttgtggatg aaagtgtcat cataggaggt cagccaatgc tacagcacaa
    51001 tgggattgct cttgaagcgc aagctttacc agatgccatt cacagtgacc ttaaaggcca
    51061 agtcattctt aaagctggtc aaaccttcac cagtaagaca cgttatgaac ttgttgtgaa
    51121 ataaaaaaag ctggtcaaaa agtctttaaa attaaaataa cgcatattgt caggtgatga
    51181 aaagtttgat aatatgcgtt ttattatgaa atgatttact ttatcttatc ctgaaatggt
    51241 gttatttttg agttatctgg cttgactttc ttgatggaaa ttatataata gttgtaataa
    51301 caataattac aacgagaaaa gaggaccatt tatgacctat gaatacaaga gtcacattta
    51361 tttggcagag acagttttaa atgtaaagga tttggccagt caaacagcct tttatcagca
    51421 agttattggt ttagaaatct tatctcaaac tgagacagag tccattctag gccttggtgg
    51481 aaaagtcttg gtacagctga ttcaagcaca agagagcgga gaagtgaggg aacattatgg
    51541 tctttaccat ttggccattc tcttgcccac acgcaaggct ttggctgatg tcttgaaaca
    51601 cctgacagat ttgcaaattc ctcttgtcgg cggtgcagac catggttaca gtgaagctat
    51661 ttacttggaa gatttggagg gaaatggcat tgaactctat cgagataagc cagtttccac
    51721 atggaatatt cgagaagatg gacgcattat cggagtgacg gaggctcttg cggcgcagga
    51781 catttatgag ttgggggaaa gagtagagcc ctttatcctg gcagaaggta caagaatggg
    51841 gcatattcat ctttccgtca aggatagtcg aaagtccagc cagttttatc aaaaggtgtt
    51901 agggctagag aataaattca gtgtgcctgg cgctagttgg attgcggctg gagattacca
    51961 tcatcattta gcagttaacg aatggggagg aaaaggtctg gcttcgcgta agcaaggctt
    52021 accaggttta gcctactatg tcatcgaagt cgcacataaa aaagaactgt taacgattgc
    52081 ccaacgagca caagaagttg acgcaccaat caaatggatg acatcgagcc aattggaaat
    52141 cacagactca gatggcatcg tgacccgtat tcgtttagca aggtaaaatt aggaattttt
    52201 aataagttat aagtattgct agtttgcttt ttgaacggtc tttggtaaca gaactgcgtg
    52261 agctggatgg gtgagaattt tgacaaagaa gctgattaga gatataatga agaaaaatcg
    52321 agcaaggaaa aagaaatgac aaattcaaag tatattactt gtttgaaacg ttcagagggc
    52381 cagttgtgtg gaattcaaaa gatgattgaa ggagatcgtg actgtgctga tattgtgacg
    52441 caactgacag cagtgaaatc tagtgtagag cgcgtgattg agatgataat taccgaaaat
    52501 cttactgaat gtatcaatca gccactagat gattctgaag ctcaaaagga acgcctagaa
    52561 aaggctatcc gatacttgat taaacggaaa taaatgaatg ttttgagacg atatgtgcaa
    52621 aggtctatta actattagaa tagtttaatg tgagtcaaaa gaagttgtaa aaaatcttta
    52681 aaattaaaaa acgcatagta tcaggtattg aaatgtactg ccccccaaaa gttagattct
    52741 ttctgtctaa cttttggggg gcagtacata aaaaccttga tagtatgcgt tttattgtgg
    52801 ggagacttat actcttcgaa aatctcttca aaccacgtca gtttcacctt gccgtagata
    52861 tggttactga cttcgtcagt tc
//
LOCUS       DAVKMJ010000009        51589 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000009 DAVKMJ010000000
VERSION     DAVKMJ010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51589
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.009"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..1387)
                     /gene="pcpA"
                     /locus_tag="VW348_000540"
     CDS             complement(<1..1387)
                     /gene="pcpA"
                     /locus_tag="VW348_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEU9745491.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNRGV"
     gene            1722..1904
                     /locus_tag="VW348_000541"
     CDS             1722..1904
                     /locus_tag="VW348_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU9745492.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            1849..2698
                     /locus_tag="VW348_000542"
                     /pseudo
     CDS             1849..2698
                     /locus_tag="VW348_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(2750..3112)
                     /locus_tag="VW348_000543"
     CDS             complement(2750..3112)
                     /locus_tag="VW348_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745493.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNIEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(3403..5283)
                     /locus_tag="VW348_000544"
     CDS             complement(3403..5283)
                     /locus_tag="VW348_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEU9745494.1"
                     /translation="MVRFIGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRHDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(5277..6146)
                     /locus_tag="VW348_000545"
     CDS             complement(5277..6146)
                     /locus_tag="VW348_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU9745495.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLTQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVEDFVDAYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(6230..8875)
                     /locus_tag="VW348_000546"
     CDS             complement(6230..8875)
                     /locus_tag="VW348_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEU9745496.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFAIECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(8966..10246)
                     /locus_tag="VW348_000547"
     CDS             complement(8966..10246)
                     /locus_tag="VW348_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEU9745497.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKNFLLDQLVACDGGTGLMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            10417..12501
                     /locus_tag="VW348_000548"
     CDS             10417..12501
                     /locus_tag="VW348_000548"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEU9745498.1"
                     /translation="MKPLLETIDTRFGTASKHAFSWGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHATDELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALLNLPQEDFDSCKASAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(12541..14220)
                     /locus_tag="VW348_000549"
     CDS             complement(12541..14220)
                     /locus_tag="VW348_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEU9745499.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGSNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGACLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGSGHTVGYKRLLRGAVVEAQKIRVVITESQALPLLTKISLYKT
                     PRLSQTVAVQGLAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            14975..16204
                     /gene="arcA"
                     /locus_tag="VW348_000550"
     CDS             14975..16204
                     /gene="arcA"
                     /locus_tag="VW348_000550"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEU9745500.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            16262..17278
                     /gene="argF"
                     /locus_tag="VW348_000551"
     CDS             16262..17278
                     /gene="argF"
                     /locus_tag="VW348_000551"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEU9745501.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            17443..18390
                     /gene="arcC"
                     /locus_tag="VW348_000552"
     CDS             17443..18390
                     /gene="arcC"
                     /locus_tag="VW348_000552"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEU9745502.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNSGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            18601..20112
                     /locus_tag="VW348_000553"
     CDS             18601..20112
                     /locus_tag="VW348_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEU9745503.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            20134..21465
                     /locus_tag="VW348_000554"
     CDS             20134..21465
                     /locus_tag="VW348_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEU9745504.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEENLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     LLYEQVCNGLKEAGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            21560..21687
                     /locus_tag="VW348_000555"
                     /pseudo
     CDS             21560..21687
                     /locus_tag="VW348_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836165.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fucose isomerase"
     gene            complement(21852..22142)
                     /locus_tag="VW348_000556"
     CDS             complement(21852..22142)
                     /locus_tag="VW348_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745505.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(22130..22381)
                     /locus_tag="VW348_000557"
     CDS             complement(22130..22381)
                     /locus_tag="VW348_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU9745506.1"
                     /translation="MKEFQFERKQRFSLRPYAIGACSVLLGTSLFFDGMGDQPVQDTE
                     TSSALILSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            22585..22662
                     /locus_tag="VW348_000558"
                     /pseudo
     CDS             22585..22662
                     /locus_tag="VW348_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(22780..23664)
                     /locus_tag="VW348_000559"
     CDS             complement(22780..23664)
                     /locus_tag="VW348_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEU9745507.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(23809..24960)
                     /locus_tag="VW348_000560"
     CDS             complement(23809..24960)
                     /locus_tag="VW348_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEU9745508.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(25106..26872)
                     /locus_tag="VW348_000561"
     CDS             complement(25106..26872)
                     /locus_tag="VW348_000561"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEU9745509.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(26929..30045)
                     /locus_tag="VW348_000562"
     CDS             complement(26929..30045)
                     /locus_tag="VW348_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEU9745510.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVSFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            complement(30055..32349)
                     /locus_tag="VW348_000563"
     CDS             complement(30055..32349)
                     /locus_tag="VW348_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEU9745511.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPRTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQDREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRV
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            complement(32408..33208)
                     /locus_tag="VW348_000564"
     CDS             complement(32408..33208)
                     /locus_tag="VW348_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9745512.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            complement(33205..33978)
                     /locus_tag="VW348_000565"
     CDS             complement(33205..33978)
                     /locus_tag="VW348_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU9745513.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            complement(34003..34473)
                     /locus_tag="VW348_000566"
     CDS             complement(34003..34473)
                     /locus_tag="VW348_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9745514.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            complement(34464..34895)
                     /locus_tag="VW348_000567"
     CDS             complement(34464..34895)
                     /locus_tag="VW348_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9745515.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISNYDSKINLEEIVHNAQNSLFNVKQQLNVEEEEDLCL"
     gene            complement(34888..35328)
                     /locus_tag="VW348_000568"
     CDS             complement(34888..35328)
                     /locus_tag="VW348_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEU9745516.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            complement(35340..35978)
                     /locus_tag="VW348_000569"
     CDS             complement(35340..35978)
                     /locus_tag="VW348_000569"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEU9745517.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMDLMAEKFKTYGQRK"
     gene            complement(36093..37496)
                     /locus_tag="VW348_000570"
     CDS             complement(36093..37496)
                     /locus_tag="VW348_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEU9745518.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDVDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELNSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGSTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            37672..38445
                     /locus_tag="VW348_000571"
     CDS             37672..38445
                     /locus_tag="VW348_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9745519.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
     gene            complement(39616..41121)
                     /gene="adcA"
                     /locus_tag="VW348_000572"
     CDS             complement(39616..41121)
                     /gene="adcA"
                     /locus_tag="VW348_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEU9745520.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(41131..41937)
                     /locus_tag="VW348_000573"
     CDS             complement(41131..41937)
                     /locus_tag="VW348_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU9745521.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(41930..42634)
                     /locus_tag="VW348_000574"
     CDS             complement(41930..42634)
                     /locus_tag="VW348_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU9745522.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            complement(42634..43074)
                     /gene="adcR"
                     /locus_tag="VW348_000575"
     CDS             complement(42634..43074)
                     /gene="adcR"
                     /locus_tag="VW348_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEU9745523.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(43229..44497)
                     /gene="dltD"
                     /locus_tag="VW348_000576"
     CDS             complement(43229..44497)
                     /gene="dltD"
                     /locus_tag="VW348_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEU9745524.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKGELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            complement(44490..44729)
                     /gene="dltC"
                     /locus_tag="VW348_000577"
     CDS             complement(44490..44729)
                     /gene="dltC"
                     /locus_tag="VW348_000577"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEU9745525.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(44743..45987)
                     /gene="dltB"
                     /locus_tag="VW348_000578"
     CDS             complement(44743..45987)
                     /gene="dltB"
                     /locus_tag="VW348_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEU9745526.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQTIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(45984..47534)
                     /gene="dltA"
                     /locus_tag="VW348_000579"
     CDS             complement(45984..47534)
                     /gene="dltA"
                     /locus_tag="VW348_000579"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEU9745527.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(47555..47686)
                     /locus_tag="VW348_000580"
     CDS             complement(47555..47686)
                     /locus_tag="VW348_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEU9745528.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(48000..49178)
                     /locus_tag="VW348_000581"
     CDS             complement(48000..49178)
                     /locus_tag="VW348_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9745529.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTCINLVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            complement(49630..50906)
                     /gene="ltrA"
                     /locus_tag="VW348_000582"
                     /pseudo
     CDS             complement(49630..50906)
                     /gene="ltrA"
                     /locus_tag="VW348_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT        15405 a        11142 c         9246 g        15796 t
ORIGIN      
        1 ctactccccg attagaattc tttttaggtt tagctacatc agtttcttgt tttatattat
       61 ctactttttc aacaatgata tcattactag tagataaatt tgatttaaga acatctttta
      121 tatgttctga tgttacatag aacttaacag tttcaggaat tgcaaatgta tcttttttca
      181 cagaaaactc tgtactttta ttcttaatat gaatttcctt taatgaatct aagacgccac
      241 ttaggaagaa ggacggcaat gagttgatat tattaccaat tgttaaactt tttaattttg
      301 gtaaaccgtt cataacgtgt ttaccaaaat ttttaacatt atctggtaat ataagttctt
      361 ttaattctaa attaccgtaa aaggctaaac gttcaatagt ttctaaacta tttggtaagc
      421 taatttcttc aagtttaatc gcatccgcaa atgcaaaagt accgattttt tctaaacctt
      481 cattcaattc gagttttttc aagtaagaat ttttattaaa cgaatatgat gcaagttctt
      541 ttgtctcttt aggcgtttta taactttcgt catttttttg acttggataa taaattaatt
      601 gagttttatc ttttgaaaac aaaacaccat caactgaggc aaacgattca tttccttctt
      661 caacatcaac atgttttaag ctagtagtga gtctaaatag attacttcct aatgttttaa
      721 ccgattttgg taatgttagt ttctctaaat ttgataaatt agcaaaagcc tcatgtgata
      781 ttaattctaa ttttgaactt gaggaaaagg ttagcttttt caatttttga ctaaaagaaa
      841 atgcacttgt tccaatatat tctagagatg caggcaattc aatctcttct aattcagaaa
      901 aatcaaaagc tctatcttca attttctcca gctgactgcc tttgtcaaaa ataatagttt
      961 tagctttact tccatggaag cctttttttt gtattttttt tatgcttgat gggatagtaa
     1021 tagagctagg atagtagaca attctacctg tttcatctgg ataataacta aaagcttgac
     1081 tagctacttc agtaacggta aatactttat cacctactgt gatttttgta ggaatcgtga
     1141 atggttttcc atcttgacca gcttcaaact ctacaggagt aactccatta cccacttgaa
     1201 cagttcctat gttaccttct acagttagaa ccttatattt gatattattt tgttgaataa
     1261 tacttccaac tttagtctct ttgattactt ccgaactagg agtatctgct aggattggtt
     1321 cattagggac atatgctgct aaaataaccg cagctgtagt taatgataat attgtagttt
     1381 ttttcattta aatttcctta catatttatt ttctaataga tataaaatta taactttgct
     1441 agccgttgtt ataaaaagtt ttattcaatc attatctagt agaatagagt agtacatttt
     1501 ataaattgtc atctctccat aaacacagta tatcattttt aaattttaag tcaaggaaaa
     1561 ttaacccact ttaatttctt ttttaacccg tgttaaaaaa gaaattaaag tgggttaaaa
     1621 aagaaattaa ctgagtaaaa actctcgaaa ttcaattcgc tatattatca ctcaacttga
     1681 acaaatacca gaaccacaaa aaacagatgt aaaggaaaaa tatggactta aaatttgaag
     1741 gggttgattt agaatacaaa aaagctaaaa acaatcttcc agagtctttc tgggaaacct
     1801 actcagcatt tgcaaataca aatggcggga aaataattct cgggatagat gaaaaaaaca
     1861 ttgacaccta ccaaagagtc aatagactcc ctgcgaaatt atgaagcaag taaacaatta
     1921 actgatacac gatttaagcg tcttgttggt gttcagcgca cgacttttaa agagatgtta
     1981 gctgtattaa aaacagctta tcaacttaaa cacgcaaaag gtggacgaaa acctaaatta
     2041 agcctagaag accttcttat ggccactctt caatatgtgt gagaataccg cacttatgaa
     2101 gaaattgcgg ctgattttgg tatccacgaa agcaacttaa tccgtcggag ccaatgggtt
     2161 gaagtaactc ttgttcaaag tggtgttacg atttcaagaa ctcctctcag ctctgaggac
     2221 acggtaatga ttgatgcgac ggaagtacaa atcaatcgcc ctaaaaaaac aattagcgaa
     2281 tcattctggt aaaaagaaat ttcacgctat gaaggctcaa gcgattgtca caagtcaagg
     2341 gagaattgtt tctttggata tcactgtgaa ctattgtcat gatatgaagt tgttcaaaat
     2401 gagttgcaga aatatcagac aagttggtaa aatcttggct gacagtggtt atcaagggct
     2461 catgaagata tgtcctcaag cacaaacttc acgtaaatcc agcaaactca agccactaac
     2521 agctgaagat aaagcctata accatgcgct atccaaggag agaagcaagg ttgagaacat
     2581 ctttgccaaa gtaaaaacgt ttaaaatgtt ttcaacaacc tatcgaaatc atcgtaaacg
     2641 cttcggatta cgaatgaatt tgattgctgg tattatcaat catgaactag gattctagtt
     2701 ttgcaggaag tctattgaaa tactaagcct acacagactg atttcaattt taccattctt
     2761 catagtcaaa accatcataa tctggatatt gttctggcga cgttccaacc gaacgtacga
     2821 gataagcttc ttcgtcctct gtctcgattt ctctcagcac ttggcattca aaacgccatt
     2881 catcaccgaa gtcgaaaata aacttaaatt tttgtttgac acttaggcta tccagataga
     2941 cattttctgt gtaacgttct tcaacatcgt cactaacaaa gctaagaaag taagaatctg
     3001 catgactcca ctcaatatta tccatgaaaa atgcgtgagc atgatcattt gcaaaatcaa
     3061 aactccataa aatcacatct gctagttccg ctaacgtttt tgtttttgga atctatatat
     3121 gtcggtagca acctttttta aatttgacgg aaatgatcca agcctctaca gatgctggct
     3181 tttcagcttc tatttcttgt tttactaatt ttaactgtag catttgaaac cagataattc
     3241 ttctgtttca cgcgaaacac cctgcgccaa gcaaggtgtt cttgttttta tactcaatga
     3301 aaatcaaaga gcaaactagg aagctagctg caggctgctc aaaacactgt tttgaggttg
     3361 tagatggaag ctgacgtggt ttgaagagat tttcgaagag tattaagtcg tataaatcgt
     3421 cgaagctgtc gcaatggtat gccactggtt agctgtagtt gctgcgaaat ccttgtctgc
     3481 gtagaagtca gtaaatggta ggatttcaac ttccagctcg tcgatgcggt caagctggcc
     3541 agccagataa acctcgatac ggctttctgc tcgtttgatg cgttgcaaga gtccgcccat
     3601 acggatgtca actgtatcca aaccaaagac cttgttttct ttcagccatt ggtgactaaa
     3661 gagggcatgg aagtcttcaa tttggcttct aagttctggt aattcttgtc tggcgatttg
     3721 ttgtaaactt tctttatcat ccgcttggta ggcctgacga atgcgtcgtc ccacatctac
     3781 tttgctactt aaaatagcat tcaactgggc ctgagtttca aagagataag catagtttcc
     3841 agctttttct ttaatgttag caagcgtctc agcagcctga gcgaagtgcg gtttgtcctg
     3901 ttcaggtgtc atgtgtcggt caagtatcgg acagagaaca tcctgataaa agacatatcg
     3961 gttgggattg atgccactga gattgcctgg taggtctggt aagaggttgg caaggtcaat
     4021 ctgcataaaa tcctcaaccg ttagaccagt attggtcttg aagtgcgcag acaaactatc
     4081 taggtcatgg cgatagctga gttctgccca gatttgcaag cttggtagga tagagaactg
     4141 ggcagtttca cccccattgt ctccccaacc cgttacgatg acttctttaa tctgattggc
     4201 acggcaggct ttattagcct cgatagccac tagacggcta aaatggttgt gaggtgtaaa
     4261 gccaatccac ttccaagctc cccctgcaaa tgcaaggtca tggctaatct tgtgatgatt
     4321 gcggaaatta cggttgtatt tttcctcgct atcctgataa taatcccagt aaaccagagt
     4381 cacacggtct ttgagacggt ctaggtagac acgagtttcc tctggaattt ccacatcacg
     4441 gtcgtactgg ccatccgctg acatgagttt gaagaacata tcactccaca tctggcagtg
     4501 gaaaccatat ttgtcagcaa tatccagcac gcgctccaag tgttggcaca tgaggagact
     4561 acgatccaca acaccgttca aaatcaggta gcgtcccaaa ccaaccaagt gggcttcgtc
     4621 catcccgata ttgaccttgc gagtcttcag tttagacaac gtggcaaaca tgccatcaat
     4681 caggtcataa accttttctt cgccaatgag aagaatgtcc tctacatcac ggagctcctg
     4741 cacttccttg acaccccatt tgacaaaggc cgacaagtgg gccaaggtct ggatgcatgg
     4801 tacaaaggtc atgtcaaact gttgggcata ggcttcgatt tcctgcaact cctctgctga
     4861 ataagctcca cggaaatagc caaagtaagg ctgtccttca atctggtaag tgtcttccat
     4921 gtaaagctca aaggttgagt agcccatgag agccaagacc tcaatcatct gcttggcaga
     4981 agccacattc agcaccgcat ttcgagaaca gtcaaccatg taagccaaat cttcgtaagc
     5041 tgcttgttcc tcaatctcta ctttatcagc ttctgctaga actgttacca acaaggacaa
     5101 ggcacgataa agttggtgag gtttgcgata ggtcaattga tagtgacctt cctcaccctg
     5161 gatagagata gatgcttggt cagactgagt gacagccact tccacatctg gtagagaaat
     5221 gtgacctttt aaaacctcaa tagcttgcgt ttgtttggga ctaagtccta taaatcttac
     5281 cactgctttt cctcctgtag ccagttgaca agagcaccgt agagattggc atctgcgtga
     5341 taggtgcagg cctggataac tggtgcgacc gtgtattctt cgtaggcatc gacaaagtct
     5401 tcaacagcct tcttaacacc ttggataaaa tctggatttt gactgataga gccacccaga
     5461 ctgatgacat ctggatcgat gagatactgg atattgagca agccttgcgt caaattgcgg
     5521 ttcatgcgct caatggcttc ttgacaaaga gcattaccag ctgcggcctc ttggtaaatc
     5581 ttgcgaccgt cccaatcagt atgaccagat ttttcaatca cgtatcgtac catattccca
     5641 gttgatgcta gttgcgacca gttattaagt ttttcagcag gggcaagggt tgtcatgtag
     5701 ccaaattctc cacccagacc gtggcgacct cgatgaagtc taccattgat aatcatggct
     5761 ccgccaatcc ctgtcccaat cacgacacag gctgcatttt caagctctgg atgagctagt
     5821 agttcactga gtccaacgca gttggcatca ttttctaaat ggacaggtag ctgataagag
     5881 ctaagcgcct cataccaaga aaagccatgg atgtagggca ccgcactgaa gccatcaatc
     5941 acacctgtct cttgattgac tgcacctgga acactcatag caatcccact gtaatcctgt
     6001 tctgacaagc gttgatctag ccacgctagt aaatcctcca agttttcagg cgttgaaata
     6061 cttgtcttat ccagtatttt cccatcagga gtcagactgg caaacttaat cccagtccct
     6121 ccgatatcaa tcgttgcaat ggtcattgtt tttaccataa aaaggggcga atcagcagtt
     6181 agttcttact ttttcgcccc tcctttcttt tgatgtttac tttttgaaat taaatttctt
     6241 cttttttgat gaattctgta cgaatctctt gtggagccaa tagtcctgaa tgaactggat
     6301 atggtcgctc aagtaagtca agaatggttt gttgatgttc tgatatgcgc acattttctt
     6361 gactcatatt atagtaacgg aggacatagc cttcttcatt ttccgccact ttaaaggctg
     6421 ttggacaaac ttgcggtatg ctgagaacag aatggctcaa gaggctacca gtcgcaacca
     6481 cgcttccttc ctgtctagca agctgaaggc tggtaaacgg tgtctgcaag gctttggcac
     6541 gacgataggc tgagaagcgt tcttgggctt ggtggcattc aatcgcaaat tcgacttcaa
     6601 actcacgcaa gcattgtgct tctggcgttg ggaagtagcc ccagtcacct agctcacctg
     6661 atgcacgcaa aatggtcacg gcaatggtgt tatccccaag gatttcgtat tcattcaatc
     6721 ccttgttgga tacagtcacc cctttttcat cgtcatacag actgacaaaa gcttgttggt
     6781 gttgaggatt ttcaggattt tcccatgaag cagctggttt gtttggtcgt gtcaccacct
     6841 catagatact ttcagaatca ttgcttggac gcgtgttatg agtcttgacc aagagacgga
     6901 tacggtgatc cttggcagtg ttagtaaagc gagtcttgaa gcggatttgt ggattgtcaa
     6961 caaagacaat caactcagtt tccagaggaa tgtttgtcaa ttcttctgac cgtccagcct
     7021 cacgcttcat aaactcgatg ataccttgtt gctcttcttc tagcttttca tccgcactga
     7081 caggcacggt caattcatgt ttgagcaaga ttttagcata gcgatctgtg ttttccaaga
     7141 cctcgtggcc cttaagctct gcaaagattg gctctgttcc ttttggttgg aaatagatat
     7201 actcgtttcc gatgtcaccc cggtcttcaa agcggataaa gtcttcatag gcttcgtgag
     7261 ttgtcttgtc atagactgtg atgttgtcat ccacactcac cgttacgaat ggtgtatcaa
     7321 tcactccgtt ttggtaaata ccctcacggt gttcttgttt tccttccagc aattggaagg
     7381 ttgtccaaga aagcggcgct aggtgaactg gaatggtcac gcgcacttgt cgagcaatac
     7441 gagcttggcg gaacttatct tttggtaaat cgtactcaaa attagctccg aggtcttcga
     7501 ttgtagcctc tacaggacga ccatccaagt cctccacacg gtaacttggc aagataagag
     7561 cagccatctt tttgtagcct tctgttgggt gcaattcctt gaaatcacaa gtcgccacat
     7621 caatcactgt gctgacagta tcgaccttat catgcaagcc tgtgttaatg acagtaaaga
     7681 gatagtcact ttgagcctta tccgtagcaa ttttaccctt ccactcgttg agcaagttac
     7741 ttttaacaaa gtttcctact tggttgacct tggcaaaacg cgtttccatc tcgcggtgaa
     7801 cttcgtccac gctacagcca cagatactat catgtggcgc gttctgcaaa agtgttttcc
     7861 aagcataggt caactggtcc ttgtggttgt gtccaccagt gataatagtc aagggttcta
     7921 ccacttgctc taggaggttg ctattttctt ggaaggcttg tttcaggtaa atgcgggatg
     7981 aagaagtgtt ggcaagtgtg taccagccat ctgtttcctg actggtcaac tcgcctgtaa
     8041 cagttgataa gtgttcagga agcgcacctt ctacagcttg aacatattca tcaaaagaac
     8101 tatgaacaaa gattacatcc gggaagagtt catttgccac acgaatggct tcgctcagat
     8161 ttttctgtac aggctggtgg tcacagccgt tcatcatcaa ccattggttg gtcgaagcgt
     8221 aggcacgcac atctgacaat ttttgtttcc agaaggtcaa ggcctcatct ttgtcaactg
     8281 ggatttcatt cccattactg taccagttgg caaagagaat acctaaaaca cgactaccat
     8341 ccacaccctg ccagtacatt tctgaaaact gggatgtaaa ctgctcatct tcaaggactt
     8401 ggttgtcaaa tccaatcggc ttcacaccac gaccaaaggc cgccacatga atgcctgatt
     8461 tttgaagaat ttgaggtgct tgtcccatat ttccaaaggt atctggaaag tagccaatct
     8521 gggttgattt accccatttg gcagcttctt gttgaccaat caaggtattg cggacattgg
     8581 cttcacttga aatcaaataa tcatcctgca agatgtaaaa gggaccaatt ttaagcttgc
     8641 cctcgtcaat gtagcgttgg accttgtcgc gattttcagg gcgaatttgt aagtagtcgt
     8701 caaggacaat agtttgtcca tccaagtgga aactcttgaa ctcagggtca ttttcaaaga
     8761 gatcaaagag attgtcaaac aattccacca actgcatacg atgactttca aaaggcaagt
     8821 accactcacg gtcccagtga ctatgtgaga taatatgtac aacaacattt tccatgaagt
     8881 aaaacctcat tctaaattta aattttaacg ttttaaatgt aaacttgtga ttctgataag
     8941 aatcggttga gctaaagcga gccccttagc gaatatccaa gtaatccaag accaactcac
     9001 agaacatcat gttagcccag gagaaccatt cacgagagta gagagttggg tcatccacgt
     9061 ggaagctttc atgcataaga cctgtaccgc catcgcaggc aaccagctga tccagcaaga
     9121 agtttttctc tgccttatct cttgttgtca agccttggat agaaagggcg attggccaga
     9181 tatagcgata gaaggtatga gaacttccaa gaccgctagc gtattctcct tggtagaaat
     9241 atggattttc agagctcaga atggtacggc gagtagcttg atacacttca tcatcgaccg
     9301 aacagtagcc cagatagggc gcagctagta gacttggtac gtttggatca tccataatgc
     9361 tggcatttcc taggccatcc acttcaaagg cataaatctt ttcaccctta ctgttggtgg
     9421 tgtaagcgta gttttcgatt ccttcttgga tttcatcctg aagacgcttg gcatcagcaa
     9481 taacactctg gctatcagct aggtttaatg ctgcgaagat ttcttgcaca taacccaaga
     9541 ctactacagc aaacatattt gacggaatca agtaactata ctggcaacag tcatcactcg
     9601 gacgaaaggc tgaccaagtc atacctgtca ctgcaaagtc aggtccaaag ccatcattta
     9661 ccaaggtgtc ttccttacgg tccgtatctc ggacaaaacg ataaggagag ttcttgtggt
     9721 cttgttcaac tgtccataga tggagaattt ccttagtcgc tgcgacaaaa gtctcatcaa
     9781 actgactagt ctcgccagtt tctttccaga ggagataagc caactgcaaa ggatagcaaa
     9841 gcgagtccac ctcatacttg cgttcccaaa tccagccatt aaggtcggtg tggtcggtct
     9901 cgtggtgccc cttccagttt tcctctatgt tgaaggaatt ggcataagga tccttgagta
     9961 ccaaggtcat ctgacgtttg accaaacctg caatggtctg acgcaggagg gcatctcttt
    10021 tagctacatg caggtagggt ctgagctggg ctgtcgaatc ccgaagccac atagcaggaa
    10081 tatccccagt caagacaaaa gttgaaccat cttctaagat ttcaaccgta ttgtccaagg
    10141 tatcggtgta gcaacgctcg aaaacatcca cccactctgg atggtcctta gcccgctctg
    10201 ctacttcatc tagccattct ctaacaattt ctttcgaata aatcatcgtg caattccctc
    10261 tttcaaacaa gtttcatgtt cagtatatag cttttgagac agaaaataca tacacaaatg
    10321 atagtcattt ttctacaaaa tagttatttt tgaaactcct tttctaaagt ccctcttttt
    10381 ctgatataat gtagaaaaac agctaaagga aagactatga aaccactact tgaaaccatc
    10441 gatacccgct ttggtactgc tagcaagcat gccttctctt ggggaaatac cctgccatac
    10501 acaggcgtgc cttttgggat gaattacttt gtgccccaga ccagtgacca ggatggatct
    10561 tggttttttg atccgcatct gcctatcttt caggggattc gattaactca ccagcccagt
    10621 ccttggattg gggactactc ttggctcctt ctgacacctg tcaccagtca actgggggga
    10681 gacagcctct ttcaccgcca gtcttcttat gatatagata aagcttgctt ccagcctcac
    10741 tatttgaagc tcttttctct gcgttatcag attgaaaccc agctcacacc gacttgctac
    10801 ggtgcttcta ttcgtttgaa gcaaaagcaa ggcaaagccc tctccctcta tcttcacgca
    10861 acagatgaac tgacagtaga gcaagtagat aagcgaactc ttgccctgcg acaagaaggt
    10921 aaaactgaaa ccaacaaaaa ttcgctaacg atgttcactg ccctgcaaat gaacacggat
    10981 attcttgcta tcagccaaga agctggggac tggcgaattg acttagcaag tagtcaaacc
    11041 gagatgcaac tagccacttc tttcatctct ccttctcaag cactgcttaa tctacctcaa
    11101 gaagattttg atagctgtaa agcaagtgcc caagcggatt gggaaaatct cctccatcgt
    11161 tttgacatta tagagacagg agaggctgac cgaaccttct ttgaccactg cctctacaga
    11221 ctcttcctct tcccacagac tttttatgag gttgatgagt cagggcaagc catccacatg
    11281 gatctggcta ctggtactgt caagcctggt gtcctcttta gcaacaatgg tttctgggat
    11341 accttccgca ccaccttccc cctctttgcc cttatcatac cggagcacta tcaacgcttt
    11401 ttagaaggtt tcctcaatag ctaccgcgat actggtttcc ttccaaaatg gctggctcca
    11461 gatgaacggg gtatgatgcc aggtacactt ttagacggta ttatcgcaga tagcgcctgc
    11521 aaggacatgg cccctgacct agaaggagaa ctcttccaag ccatgctcga aacagccagc
    11581 aaagccgacc ctctcggaat caatggccgc cacggactag cccaatacca agaactaggt
    11641 tacctctcta ccgaccacca cgaaagtgtt agccatactc tagactatgc ctatagtgac
    11701 ttttgtatcg ccagctgtgc caaaaaacta gagaacatag aaatcgctga aacctacaag
    11761 gctgcttcac aaaattaccg ccagctattt gacgctgaga caggttacat gcgagcacga
    11821 gacaatcaag gaaactttca ccctgacttc tctccttata gttgggggcg agactacgct
    11881 gaatgctctg ccattcaagc tactttaggc gttctccacg acatccctgg cttaatccaa
    11941 ctgatgggtg gaaaagaaac ctttagcaac tatcttttga aagcctgtca agatgctccc
    12001 ctctttgaaa caacaggcta tggttacgaa attcacgaaa tgagcgagat ggctactgct
    12061 ccttttggac aaatagccat ttccaaccag cctagtttcc acattcctta tctcttccgc
    12121 tacagcgatt accctgacta cactgccctt cttatcaaga cgctccgtca gaaagctttt
    12181 cacccaagtt gggaagccta tcctggagat gaagacaatg gtagtctctc tgcttggtac
    12241 atctggtcag ctctcggatt ttatccaacc tgtccaggaa aaccaagcta tgacctcgga
    12301 atccctctct ttgaccatct acgagtctac ctcgctaaag aagataaatg gctggatatc
    12361 catactaaac aaaaccacaa ccattttaac tttgtcaaag aatgccgact ggacaaaaca
    12421 ctcgtatcaa ctattcaaca ccaagacctc ttaaaagctg aacaactaac tttcaccctc
    12481 agctggttac caagtcacta ataaccaaaa gaacctttgc atcgcgcaaa ggttcttctt
    12541 ttatgaaact tggacttgaa gttgatccac aagctgacca tccaccgtta ggttcagata
    12601 gaaatccaag gttttatctc ctgcgaaata cagggttggt agatgcaaat cttttttgct
    12661 ttcccctgct tggaattgaa ggacttgaat ctcatcctga taggcgacac catggacacc
    12721 tgtccccggt tgaatcgaaa tcttagcctc taaagaggag ctactttcac tacgttcaat
    12781 cctaaaatga agagtctctc cctttgccac agctaggctt ttttctgcaa atgctagccc
    12841 ctgaacagct actgtttgtg ataacctcgg agttttatag agtgaaatct tggtcaacaa
    12901 aggcaaagcc tgtgattctg taatgactac acgtatcttc tgtgcttcaa caactgctcc
    12961 tcgtaagaga cgtttgtaac caacagtatg acccgaacca aactcctgcc agacaccatc
    13021 cacctctact tgcacatgaa aagcagcgat tcgttgccct agcttcaaat cttctcttaa
    13081 ctcaattaca tcaaaagttt taggagaacc taagtcgagt tctaactgga tgggcaagtc
    13141 tgcatcgctt gcccaagagc tggtctcaag gccgtctgtc aaatggcgac aagcaaagtc
    13201 tgcggaaaga gctggaccag atacctcagc tcccagagcc aaatcttctt tatagagctc
    13261 attgcgatag gtcgcaaatt cataaagtcg ttcaatatcc tttgcatcaa agagcccagc
    13321 ttgattcggc ggaatattaa gcaagagtgg agttcctcgc cctactgagt gaaagtagat
    13381 ttcgaccaac tcctcgagag acttaggatc ctgatcctca tggtagaacc agcctggacg
    13441 gatggaaaca tctgcctctc cgattgaaaa aatcgtgccc gagggatccc cgtgctgaag
    13501 atagttcagc tctgcttctg ttcctagttt atcaggattc accttttgcc acagtggatc
    13561 acctgcatac cctcgttcat tgccaatcca gcggatactg gtgccttctg ttgaaaaaat
    13621 caagcaagcg ccctgcaggt cacgaatggt ttcaaaccat ttttcaaatt cataattaac
    13681 cttttgcgcg ccctctcctc tggcaccatc catccaaacc tcagcgaact taccagcatt
    13741 cccatagtta ggatttgata agatttcctt caactgagcc agataatagg cattgtagtc
    13801 cgcttctcgg tccacatgat agaggggact atgggcatcc cacggtgaca ggtagacccc
    13861 catatccata tcaaactctg tggcagcttg ggatacttca aggagcaagt cgccctttcc
    13921 tctcctccaa ggactgacct taaccgaata atctgtgtga gctgtcggat aaaggacaaa
    13981 gccatcgtgg tgcttgacca ccaaaatcaa ctttttgaag cccgtttcct tgagcacacg
    14041 aacccactca cgcgcatcca actgactcgg gttaaagcgc tcaggatcct cctgtccagt
    14101 cccccattct tggtcataaa aggtattaga accgaagtgg ataaaagctg ctagttcatc
    14161 tcccagataa gctagctgag tctgacttgg taacggtcca tgcggtttga ttttcttcat
    14221 cgttatatat ctccttcttt agcaacttct cttgttcaca aggttatcca caggttgtgg
    14281 ataataaacc atgatctaac agccagctct ttccaactcc aactggtagg ctcaggattt
    14341 ttctcctcaa tattccctct tcaaacagct ctgtcatatg gttctgctaa cacctctcag
    14401 aatgctactc tccataatta ttctcaggct tctttcaggt cattgtgtga agaccattca
    14461 ctctccagac ttttccacag attgtgaata agtgattatt ctaaactatc acctcgtcga
    14521 ctataacaaa aaataaaaag agggtcaata agataattat ctcttcctaa atactcagaa
    14581 aagattctat aatttgtaca attgaacaag aaatgcttct ccaaaatcta tcttcaaaag
    14641 aatgttgcat ctttttatcc tttcacacaa acatttctct ttatacagat ccaagtgata
    14701 accagatgat aattggacac tttttggtca tttgtatatt ttttgaaaaa ttttttaaaa
    14761 aaattttata tcctttttat agaagtttat gcatttgtat ctatgtattc tatcctatgt
    14821 tatgtataat aacataaaat tgtgctaaat attataattt atattatttt ccgagaaatt
    14881 atagccattg acattaccta ggaattgcgt tataacatac atgtaagcgg tacccaaaat
    14941 ggtgccaagt caaaattttt aaggaggaaa atacatgtct tcacatccaa ttcaggtctt
    15001 ctcagaaatt gggaaactga aaaaagttat gttacaccgt ccaggcaagg agttagaaaa
    15061 cttgttgccg gactatcttg aaaggcttct ttttgatgat attcctttct tggaagatgc
    15121 tcaaaaagaa catgatgcat ttgcccaagc tcttcgcgat gaaggaattg aggttctcta
    15181 cctagaacaa ctcgctgctg aatcattgac ctctccagaa atccgcgatc aatttatcga
    15241 ggaatactta gacgaagcca acatccgtga tcgtcaaacc aaggttgcta ttcgtgaatt
    15301 gcttcacggc atcaaggaca accaagaatt ggttgaaaaa acaatggctg ggattcaaaa
    15361 agttgaattg ccagaaattc ctgacgaagc taaagatcta actgacttag ttgaatcaga
    15421 ttatccattt gcaattgacc cgatgccaaa cctctatttc actcgcgacc catttgcaac
    15481 aattggaaac gccgtatcgc ttaaccacat gtttgcagac actcgtaacc gtgaaacact
    15541 ctacggtaag tatatcttca aataccaccc aatctatggc ggaaaagtgg atttggtcta
    15601 caaccgtgaa gaagatacgc gtatcgaagg tggagacgag ctagttcttt ctaaagacgt
    15661 ccttgcagta ggtatctctc aacgtacaga cgcagcttct atcgaaaaac ttttggtcaa
    15721 catcttcaag aaaaatgttg gcttcaagaa agttttggcc tttgaatttg ctaacaaccg
    15781 taaattcatg cacttggata ctgtcttcac tatggtagac tatgacaagt tcactattca
    15841 cccagaaatc gaaggcgacc ttcacgttta ctcagttact tacgaaaacg aaaaacttaa
    15901 aatcgttgaa gagaaaggtg acttagctga acttcttgct caaaaccttg gtgtagaaaa
    15961 agttcatttg attcgttgcg gtggtggcaa tatcgtagca gctgcgcgtg aacaatggaa
    16021 cgacggttct aacactttga ccatcgcacc tggtgtggta gttgtttatg accgcaatac
    16081 cgtgaccaat aagattttgg aagaatacgg gcttcgcttg attaagattc gcggaagtga
    16141 attggttcgg ggccgtggtg gacctcgttg tatgtctatg ccatttgaac gtgaagaagt
    16201 gtaatcgctg ttcggcattc gtcaatagaa aatgtaaaaa atagaaagag gaaataataa
    16261 aatgacaaat tcagtattcc aaggacgcag cttcttagca gaaaaagact ttacccgtgc
    16321 agagttagaa taccttattg gtctttcagc tcacttgaaa gatttgaaaa aacgcaatat
    16381 tcaacaccac taccttgctg gcaagaatat cgctctccta tttgaaaaaa catctactcg
    16441 tactcgtgca gcctttacaa ctgcggctat cgaccttggt gctcacccag aatacctcgg
    16501 agcaaatgat attcagttgg gtaaaaaaga atctactgaa gatactgcta aagtattggg
    16561 acgtatgttt gacgggattg aattccgcgg attcagccaa cgtatggttg aagaattggc
    16621 agaattctca ggcgttccag tatggaacgg tctaactgac gaatggcacc caactcaaat
    16681 gctcgctgac tacttgactg ttcaagaaaa cttcggtcgc ttggaaggct tgacattggt
    16741 atactgtggt gatggacgta acaacgttgc caacagcttg ctcgtaacag gtgctatcct
    16801 tggtgtcaat gttcacatct tctcaccaaa agaactcttc ccagaaaaag aaatcgttga
    16861 attggcagaa ggatttgcta aagaaagtgg cgcacatgtt ctcatcactg aagatgctga
    16921 tgaagcagtt aaagatgcag acgttcttta cacagacgtt tgggtatcaa tgggtgaaga
    16981 agacaaattc gcagaacgtg tagctcttct taaaccttac caagtcaata tggacttagt
    17041 taaaaaagca ggcaatgaaa acttgatctt cctacactgc ttgccagcat tccacgatac
    17101 tcacactgtt tatggtaaag acgttgctga aaaatttggt gtagaagaaa tggaagtaac
    17161 agacgaagtc ttccgcagca agtacgctcg ccacttcgat caagcagaaa accgtatgca
    17221 cactatcaaa gctgttatgg ctgcgacact tggtaacctt tatattccta aagtataatt
    17281 ttagataata aaccgtctac caacagctat gagggctgcg actaatagct ttagtccggt
    17341 cctcttttat gtaatggtaa tctattattt cttataaaat atgtgaaaaa tcattaaatt
    17401 gaaatctaaa cgcattctat tgagtgtgat aaaggagaat ttatggcaaa tcgtaaaatt
    17461 gtagtagctt tgggaggaaa tgcgattctt tcttctgacc catcagcaaa ggctcaacaa
    17521 gaagctttag ttgaaacagc taagcatctt gtaaaattga ttaaaaatgg agatgatctg
    17581 attatcactc acggtaatgg acctcaagtt gggaatctct tgctccaaca tttggcatca
    17641 gactctgaaa agaaccctgc cttcccactc gactcacttg tcgctatgac agaaggtagc
    17701 atcggtttct ggttgaaaaa tgctttgcaa aatgctctct tggatgaagg catcgaaaaa
    17761 aacgttgcct ctgttgtaac gcaagttgtc gtagataaaa atgatccagc ttttgttaac
    17821 ttgagtaaac caatcggtcc tttctattca gaagaagaag caaaagcaga agccgaaaag
    17881 agcggagcga ctttcaagga agatgctggc cgtggctggc gtaaggtcgt tgcctcacca
    17941 aaacctgttg acatcaaaga aattgaaacc atccgtactc ttttaaatag tggtcaagtc
    18001 gtcgtagctg caggtggtgg cggtattccc gtcgtcaaag aaaacaatgg acatttgact
    18061 ggtgtcgaag cggttattga taaagacttc gcttcccaac gtttggcaga attggttgat
    18121 gcagacctct tcatcgtttt gacaggtgta gattatgtat ttgttaacta caacaagcca
    18181 aaccaggaaa aattggaaca tgtgaatgtt gcccagctgg aagaatatat caaacaagat
    18241 cagtttgcac caggtagcat gcttccaaaa gtagaagcag ctatcgcttt tgtcaatggt
    18301 cgtccagaag gaaaagcagt tattacttcc cttgaaaatc taggcgcctt gattgaatct
    18361 gaaagtggaa caattattga aaaaggataa gttgttttac taataagatg tattctattt
    18421 ctagtatctt tatatcaaat tagaaattat tcttgaaaac atgtacaata tttcaaaaga
    18481 tattagtttt ttagacttta atatggtaaa acaaatataa atagaaagcg ttttcttaaa
    18541 tgtttattta agaaagtagt tggtttttta cactttgtta gacatcagga ggaaaaacaa
    18601 atgagtgaaa aagctaaaaa agggtttaag atgccttcat cttacaccgt attattgata
    18661 atcattgcta ttatggcagt actaacttgg tttatccctg cgggggcctt tatagaaggt
    18721 atttacgaga ctcagcctca aaatccacaa gggatttggg atgtcctcat ggcaccaatt
    18781 cgggctatgc taggtactca tccagaggaa ggttcgctca ttaaagaaac gagcgcagcg
    18841 attgatgtag ccttcttcat ccttatggtt ggtggtttcc ttggcattgt caacaaaact
    18901 ggtgctcttg acgtagggat tgcctctatc gtgaagaagt ataagggccg cgaaaaaatg
    18961 ttaattttgg tactaatgcc tttgtttgcc ctcggtggta caacttatgg tatgggtgaa
    19021 gaaacaatgg ccttctatcc actccttgtg ccagttatga tggccgttgg ttttgatagc
    19081 ctgactggtg ttgcaattat tttgctcggt tctcaaatcg gctgtttggc atctactctg
    19141 aatccatttg cgacaggtat tgcttcagcg actgcgggag ttggtacagg ggacggtatc
    19201 gtacttcgtc tgatcttctg ggttaccttg actgctctta gtacttggtt tgtttaccgt
    19261 tatgcggata agattcaaaa agatccgact aagtcactgg tttatagtac tcgcaaagaa
    19321 gatttgaaac actttaacgt agaagaatct tcatctgtag aatctacact tagcagcaaa
    19381 caaaaatcag ttctcttctt atttgtgttg acattcatct tgatggtatt gagcttcatt
    19441 ccatggacag accttggcgt taccattttt gatgacttta atgcttggtt gactggtctt
    19501 ccagttattg gtaatattgt cggttcatct acttctgcac taggtacttg gtacttccca
    19561 gaaggcgcaa tgctctttgc ctttatgggt atcctgattg gtgttattta tggtcttaaa
    19621 gaagataaga ttatctcttc cttcatgaat ggtgctgctg acttgctcag tgttgccttg
    19681 atcgtagcga ttgctcgtgg tattcaagtt atcatgaacg acggtatgat taccgataca
    19741 atcctcaact ggggtaaaga aggcttgagc ggtctatctt cacaagtctt tatcgttgta
    19801 acttatatct tctatctacc tatgtcattc ttgatcccat cttcatctgg tcttgccagc
    19861 gcaactatgg gtatcatggc tccacttgga gaatttgtaa atgtccgtcc tagcttgatt
    19921 atcactgctt atcaatctgc ttcaggtgtc ttgaacttga ttgcaccaac atctggtatt
    19981 gtgatgggag ctcttgcact tggacgtatc aacattggta cttggtggaa attcatgggc
    20041 aaactcgtag tcgctattat tgtagtgacc atcgcccttc ttctccttgg aaccttcctt
    20101 ccattcctat aaaatagtga gtgaggtgat tccatgaaaa tagatataac aaatcaagtt
    20161 aaagatgaat ttcttatatc attaaaaacc ttgatttcct atccttcagt actcaatgaa
    20221 ggagaaaatg gaacaccttt tggacaagca atccaagatg tcctagaaaa aactttagag
    20281 atttgtcgag acataggttt cactacctat cttgacccta aaggttatta cggatatgca
    20341 gaaatcggtc agggagcaga gcttctggcc attctctgtc atttggatgt tgttccatca
    20401 ggtgatgaag cagattggca gacaccgcca tttgaagcaa ctatcaaaga cggctgggta
    20461 ttcggacgtg gtgtccaaga tgataaaggc ccttcgctcg cagctctcta tgcagtaaaa
    20521 agcttgctgg accaaggtat tcagttcaaa aagcgcgtac gctttatctt tggtaccgat
    20581 gaggaaaacc tctggcgctg catggcacgc tacaatacca tcgaagaaca ggccagtatg
    20641 ggctttgcac ctgactcatc ttttcctctg acctatgctg aaaaagggct tctacaggtc
    20701 aaacttcatg gcccgggatc ggatcaacta gagcttgaag taggaggcgc ctttaacgtt
    20761 gtaccagaca aggccaacta ccaaggtctt ctctatgaac aggtttgtaa cggtctcaaa
    20821 gaagctggtt atgattacca aaccactgaa caaaccgtaa cggttctcgg agtgccaaag
    20881 catgctaagg atgctagtca aggtatcaat gctgtcatcc gactagctac cattcttgct
    20941 cctctccaag aacaccctgc tctcagtttt cttgcaacac aagcaggtca agacggcaca
    21001 ggaagacaaa tctttggtga tatagcagat gaaccttctg gtcacctatc ctttaatgtc
    21061 gcaggtctca tgatcaatca tgaacgttct gaaatccgta ttgacattcg gactcctgtc
    21121 ttagctgaca aggaagaact agtagagttg cttacaagat gtgcacaaaa ctaccaactc
    21181 cgctacgaag agtttgacta tctagcgcct ctatacgtcg caaaagacag taaactcgtt
    21241 agcacactga tgcaaatcta ccaagaaaag actggcgata acagtcctgc tatttcatcc
    21301 ggtggtgcca cttttgctcg caccatgcca aattgtgtag ccttcggcgc cttattccca
    21361 ggagcgaagc agacagaaca tcaggcaaat gaatgtgccg ttctagaaga tttgtaccgt
    21421 gctatggata tttatgccga agccgtctat cgacttgcaa cttaatcagg caactgtttc
    21481 tacaaaaaaa aatcgaccga ttaatgaact gcaccccaaa agttagacag aataaatcta
    21541 acttttgggg tgttttatta tgaaattgaa ttatgaagat aaagttcaga tctatgaact
    21601 aagaaagcaa ggacaaagct tcaaacagct ttcaaaaaga tttatgtgga tgtttctggt
    21661 ttaaagtcat ctgaatcttt gagatgagct ttataaatcg cttttttcag tgtttgcact
    21721 ggtgtttcga taaactcaaa ctttttagcc gtggtattgc ctgattttat agtatattga
    21781 aactagaata gtacacctct acttctaaaa catttttaga aatcgatttg tcctgttctt
    21841 atttcatttt actatatttg agccacttcg tctttaacgg ctttattcat aagctcttgt
    21901 aatttttctt tactatcaat tacttctgat tttccgttgt aatttattgt aataggtttt
    21961 aacttaccta atttctcgac acgctcatta atttgatctt ttttgaaggc tgcatatgtt
    22021 tttcctaaga ttttttcgaa aatatattta tcagatagcg gtttgccttc ttcttcagct
    22081 tggtttttgt attgatttga aacataagga acaaatcctt catagtaacc taatgctccc
    22141 ataagttcaa aagcttgttt tctaattcaa accattgcaa ctcagatttc agcttttcag
    22201 ataaatcctg ctcatccaaa taatgactta aaattagtgc tgaactcgtt tctgtatcct
    22261 gtacaggctg atcacccata ccatcaaaaa ataaactcgt tcctagcaag accgaacaag
    22321 ctcctattgc atatggcctc aaagaaaaac gctgctttct ctcaaattga aattctttca
    22381 tcccatctcc catcattcat tattactgta tattttgtat atcagaaata gtttgtattc
    22441 acaaatcttt ctagttattc ccttatcatt cctaattaag ggagataaca tacaataatt
    22501 tttagttaaa tgtatatcga tgttttttgt ttttcttaat aaacgcaata caaaaagagc
    22561 ctgttgccaa gctctttgta ctcaatgaaa atcaaagagc aaactaggaa actagccaca
    22621 ggttgctcaa aacaccgttt tgaggtagta gataagactg acgaagtcag ctcaaaacac
    22681 tgttttgagg ttgcagatag aactgacgaa gtcagtaaca tctatacggc aaggcgacgc
    22741 tgacgtggtt tgaagagatt ttcgaagagt attagtctat tatttcttct cagcgcgaag
    22801 ggctgacaag atttgtgttc ggatatcatc cacaccattt ggagtatttg gtaaaaagat
    22861 ggtttgattt cctttagagg caaaggtatt caaggtatcc aaatactggt tggtcaagag
    22921 gatagacatg atttgttctt ctgtcatgcc aacattggct tccttgagtt cggtgataga
    22981 ctctgccaat ccatccacaa tcgccttacg ttgttgggca atccccacac catgaaggcg
    23041 gtctttttct gcttcggctt cagctgcagt gacaatttta atcttgtcag cttccgccaa
    23101 ttcttgtgct gcgacccgct tacgttgcgc cgcattgatt tcattcatgg attgcttaac
    23161 ttctgcatcc ggttcgactt tggtaatcaa ggttttcacg ataatgtagc cgtaagtggt
    23221 catttcttct gctacttggt gttgaacctc aagggcaatc tcatcttttt tctcaaacaa
    23281 ttcatccaag gttaattttg gaacagaaga gcgaagagca tcttcgatat aagatttaat
    23341 ctgagattct ggacgtatga gtttatagta agcatctgtc acgctctgct cgttgacacg
    23401 gtactgagtc gctacattca tcataacgaa cacattgtcc ttggtcttag tctcaaccac
    23461 aatatcactt tgcaacaagc gcaactgaat ccgtgctgca atcgagtcaa tcccaaaagg
    23521 caagcgaata tgaataccgc tattagcaac cttttggtat ttcccaaagc gttcaataat
    23581 cgccaccgac tgctgacgaa ccacataaac tgtactcagt gtgactatca ccaataggag
    23641 cacacaaaca atcagaaaaa tcatgaaaaa tattgccata atggaacctc cacaagtatt
    23701 tttctagtat tatagcacat ttaaagaagg ctgtgccgtt tttactgcga tttttcctga
    23761 aatgtcaata attagaggtg aattgtccta ttgtcgtcca atctcttgct aaaataactc
    23821 tttataaaag gcaatcgttt cttctaaggt tggcataaat ggatttcctg gtgcgcaggc
    23881 atcaatcaag gcattcttag aaaggtattc aaagtcgaaa tctttttctt caataccaag
    23941 ttcagtcagt ttcttaggaa tacctactgt ctcagaaagc ttctcaatct caacaatcgc
    24001 ataatcggca cattcttgat ctgatttacc ttctacatga agtcccaagg ctttggcaac
    24061 attgcggaaa gcttctggta cacgtttagc attttcacgt tctataactg gtagcaacat
    24121 ggcacagcaa acaccatgtg gcaaattata tactgcaccg agttggtgag ccattgagtg
    24181 aacataacca agaccagcat tattaaagct cataccacca aggaagatgg cattgaccat
    24241 accttcacgc gcttcaatat catgtccatt ttctacagca cgaggaagat attccttgat
    24301 aagctcaata gcaccaatag acagtttctt ggttacatca taagcaccag gtgttaccaa
    24361 agcttcaaca gcgtgagtca gagcatccat accagtagca gcagtcaggc ctttaggttt
    24421 ggaaagcatg agttccgggt cattaacaga gataagagca aggctattct tgtcaaccat
    24481 taccatctta accttgcgtt cttcatcagt aatcacatag ttaatagtga tttctgcaga
    24541 agttcctgcc gttgtattga tagccacaac tggcaagcct tttttagcag acttatgaag
    24601 cccttcataa tcctgtggtt ttccaccatt tgtagccatg atagaaatac aactagctgc
    24661 atcctgtgga gaacccccgc caagactgat gataaagtca cagccatgtt cttgcaaagc
    24721 agctacccca tctgtgacat ttttacaagt agggtttggc tctacatcgc taaagatgac
    24781 atattcgatt ccttctgtat ccagtggttt taaaacctta ggtaaaatgt cactgccttc
    24841 gatgtactta tctgtcacca aaagtgcctt tttatagcca agttccttga tataaggacc
    24901 cacttcattt acaacacctt taccaataag gttgactgcc ggaacataaa atgtagccat
    24961 ataattttcc tcctgcgcct ccgcgctatc tatttaacat cattatatta gtttttgtat
    25021 tcgttttcaa ttatttgtga attgtttaac aaatcttttt aaaaggatag gagggacata
    25081 agttcacctc ctatatacac aatttttatt tatgtagcgg tcccaacaac tgacatgcac
    25141 gatagtctgc tgattctaga tcttctgttc caaataagga ccaattttta ggtctaaaga
    25201 tatcttcctc gggtacatta tgcatattga caggaattct caacatagaa gccaaggtaa
    25261 tcaagtctgc tccaatgtgt ccatatgtta tggctccgtg attagctccc caattattca
    25321 tgacgtcata gacagacttg aaagcacctt ttcctgtcaa acgtggagca aaccaagtag
    25381 ttggccatcc tggatctgta cgattatcta aagtatggtg aacatcttca ggaagttcaa
    25441 gtgtataacc ttctgcaatt tgtagcactg gaccaacccc ttttagaaga ttgagacgta
    25501 ccattgttac tggcatatcc cccttcgtca agaaacgagt tgagaatcct cctccacgga
    25561 agtattcgcg gtttgctggt gggaagtctg tattttcaag catagcctgc acttcacttt
    25621 cttccaactc ccagaatggt ttcataacag gtttgccatc tcgagtagct tgccctgtac
    25681 catccaatgt acaagaacca gagttgatta gatgtaagaa gccagctgca gcacaaccct
    25741 ctaaagtatg tcccgttaca cgtttaacag cctctggact ccaataagtg cgcacatcag
    25801 caaagatttg tggagtattt gttaatagat aattaaagag catagacaca ccatttagtg
    25861 aatcattctc tgtcgcaaat acaaatggtt ttcgaatacc attccagtca aactgagtat
    25921 tgaggaaagt ttccataaag tccccatttg ggaaatggtc tgtccactga cgttgacctt
    25981 ggaaaccagc tactaaagca tggtgaccaa ctgcttcttc ctcaaaacca agttcagcaa
    26041 gtcttgggtt accaaccatt aagtcacgtc caatcatgaa catcttaata acaaattccc
    26101 attgtctatc tttttcttca cggcttaaaa caaggtcttc acggttatgg tcgaatcctt
    26161 cttttacgtt ttctttcacc catttgagcg cacgttcgaa ctcttcaggg tcgtaaatac
    26221 cacggtccat acggcgtgtg aactccgtca tatctaccga ttcatttcgc attcctaggt
    26281 attcttggaa gaaatccgga tttacaatag aaccaccaat ccccatcgaa acactcccca
    26341 ttgataagta agctgtatct ctcatcaagc cagttgcaag agctgcccgc gcataacgta
    26401 aaagtttttc tttgacatct tctggaatag ctgtatcatt agcttcctga acatctctac
    26461 cataaatccc aaaggctgga atcccttttt gagcatgtga agctagtaca gctgcaagat
    26521 agacagctcc tgggcgttct gtcccattaa atccccaaat agcatgagga atatctggag
    26581 acatatccat agtttcacta ccataacacc agcatggtgt aactgtaatt gttgcgcaaa
    26641 catttgattt tttaaacaac tcatgggaag ctgcagcctc tggaacacga ccaatggtag
    26701 atggagaaat cacacattcc acaggttccc catctggata tttcaatgtg cttgaaatca
    26761 aatctgccac acttttagcc atgttcattg tttgtacttc aagtgattcg cgtacacctt
    26821 gacgacgacc atcaatagtc ggacgaatcc caatacgtgg atgttgaatc atactatttt
    26881 cctcttattt ttctgtttct ttcatactac cgatgataat ttttaaaatt acttataagt
    26941 ataaacctct acctctgcca aacttaaagg aattcctgcg tttctcaaag aaattctaac
    27001 cttttttccc ttcagccctt ttaagtctat ggatagatta ttgctttcta aactgtcaat
    27061 atgttgttta aaaacttcat gattatttga atcatatata ataatatcaa aatttgataa
    27121 tctctgaatt tcagcatctg ttctattata aataattaac ttttctaatt cttcggtttg
    27181 tgctaaatct atctcccacc atgaaggaga atctcctttg gtatgagtca ctgaatgatg
    27241 accataatct ccgtttttat ttccatcaac tgctagacga gaaaaaccat tgtaatccgt
    27301 tgaactctgt cgagtttctt tggttaatgc aatattagaa agtttcttcg gagttctctt
    27361 tgaaccatag acttcaactt ccgctaaact taacggaata gctgctgatt ttaattctat
    27421 tttgactagc ttagccccta cagaaggtac ttttaaagat aacaaaccat caactacttt
    27481 atcaaaatgt cttctaaaaa cttcttctcc tgatgaagat agaaaaataa catcaaaatt
    27541 agataaacgc tgaggttcgg catctgttct attataaata tcaactttag aaaccgtaaa
    27601 ctcttctccc agatcgacct gccaccaagc gttagaatct gccttagtat gagtcaccga
    27661 atgatgtccg taatctccat ctttattacc atcaactgct aaagcagcta caccctcata
    27721 attggttgaa ctttgagtag ctaccttatt tgtagagact actttatctt ctgttatttt
    27781 atctatatcc tcttcagatt gcttaccatc tgattctcta aaaacctcta cttctgctaa
    27841 actcaaaggc actccactcg ttagtaattt aactttaata taccttgctc ctttttcttt
    27901 gaaatctaga ctaacagatt cacccgacaa attattaaca tgtttcttag caacttcgtt
    27961 tctattattg tcatatagaa tcacatcaaa attagataga cgttgagtct cagcatctgt
    28021 gcgattataa attttaacaa gcccaacttt atccattttt ttcaaatcga cttcccacca
    28081 agagggatta tctgccctag tgtgtgttac cgaaccagag ttaaaattac catttctgtt
    28141 accatccaca gctctattag ggtctccatt gtaatctaca gaactttgtg ttgttggttt
    28201 tgcatatgct atattcaaat taccatcatt aaatttatct ggtgttggga aagagactgg
    28261 acctgtcccc tcagtattta tagacatctc taccattcca ttatgattaa ccgtaatggt
    28321 ataaacatgg gtattctcat cccaattttc tgtataagta taatgatttt tatcgccact
    28381 tatatttatc tgaggtttat gaccagtatg cccttttaat gtaagtgttg ttgtcctaaa
    28441 gtcattatct acaggattga tggaataatt tttgcttatc cagttcgcta actctaattc
    28501 ttctttcttc caactttttg atgcatcaaa atttcctgat aatgcccaca tagctgtctt
    28561 atctgtcctg taattattca ataaaatatg taaattattt ggattttctt taacaacagc
    28621 gtaagtatgt ggcgtcaaat ctaacgataa cgactttgta ttattagtat acataggcaa
    28681 cattacttgc tgatttttat tgatattagc attactatta taaatatacc aggaattacc
    28741 tacacgctga gcatacccat ctccttcata aagttttgga taaagcgagt ttaaatagtt
    28801 gactttacta gacaattcct cactattttt agtcaaaatt tttgcattag ggaatataga
    28861 tgaaatcttt tccttatcaa ttttctcatg tattacagga agaatatgat atctcccatt
    28921 attatataaa ggcattgttt catcattcga ataaagtcct tgataaaatc cgtttaatga
    28981 actaatccta ccttctccat tccaaaatac agcttttgtt ctatttacaa cttcttcctt
    29041 acttggagct ggattttgta tagcatgtct aaagaaagga ataatacctt tagtaaatgc
    29101 tggagttggt acatcatttg tcataaatgt atacgcggca cattcgaaat tataaactgt
    29161 gcctccccca gtatatacat tcatcatttc catagcaatc attgattctg gttccgatgc
    29221 ataggatctc atatccctag ctcttccagt ttcaaatgtg tttgtataat gtttttccca
    29281 ccatttccat gtatctgttg atgagcccca gttatcacat aagccactca accaaaatcc
    29341 actaacgata gaatctgtac ccgcatcatc tcttattggc gtatttttag ttgccaacac
    29401 caaattttta tgatattttt gactcgcttc aaagaatgtc ggatcattca taatagtttc
    29461 ccagaaccat ttttcatgat catgccagat aaaatgcgct ccatatttgg cacaaacttc
    29521 caaatattta gcactatgcg gagctaactg gttattgtaa atccaataat tctcaatatt
    29581 taaaacacct tttaacacac tatacttttg gaattgttca tctaaccact ctggaggaac
    29641 tgtattacgc tctccagccg acataataac caagaaaact ggaatgttta gactttgagc
    29701 ttcctccaac atcttgacat accattctct caattctttc gtatctcgtg gaatacaact
    29761 tgttggttta cagacttttg caggatgaag ttcaatcgct gcatatggtt ttacatcttc
    29821 aggaatagct tcccatgctc ccttcaatgt gttcccccac cataatccgt taccattatc
    29881 attgccatac aacggagaaa gcaacaatgg cgattcatta ttaatcgtcg ttctcatttg
    29941 aacacgatta tcagccttaa ctcctgctaa caatccaaaa cataacatcc caatacatac
    30001 aaacagtatt gtgattaatt ttctttttat tttttcttta ttcatgactt atacctaaaa
    30061 atttaactca ataatttttt ctgaattaaa taccaattca atattttgta catcagtatt
    30121 tttgccatat actcttactc ttactttttg atctttgttt cctccttcca attttaggaa
    30181 tgttatatcc ccatttttcc aagcaaacga taccttatat cctcctctta ctctgaaacc
    30241 tttcacttct ccttctgacc aagcagaagg taaagctgga attagtgata accaattatg
    30301 atggctctgt actaataatt cacaaattcc actcaccaaa cctaaattac catcaatttg
    30361 aaatggtgga tggtcaagaa ataaattgcc aagagtcgca ttatttaaca aaccattaat
    30421 ctggttataa gcaggttcac cttgatatag tctcgcaaaa aaatgaatca gccatgcagc
    30481 actccaacct gtttgtgtac tagcatgcaa accacttact aaccaattat taatcgcttg
    30541 ctccctatcc tgtgaagata aaaagttagc gtttgataat cttctattga tagtgatttt
    30601 agctgcttct gctaattccg gagttttatg aatatcaatc tcattataag gataaagccc
    30661 aaatagaggt gaaatgtgtc tatgaccagg ctctacttct tcataatcct ctagccattc
    30721 ttgtatttgc ccattactac ctatttttgt tctaggtaat ttctttttta actccttcac
    30781 acgactaata aaatccgaat tgtctcctaa ttgttttgca attccaatgc atgaatcaca
    30841 aaaatatctt aaaatttgat tatcaattgt agatgataga caagcatttc cttcaatacc
    30901 attttttaag cgatatttat tttccggtga gacacttgga cctgtcatca agtagccatc
    30961 cacctcaaat aaataatctt caaagaaaag aaatgcttct tttatcattt caaaatgttc
    31021 cgtaagaata cgctcatctt ggaaatataa atagtgttcc caaatatgag tacataacca
    31081 tggaatagtt aatacccaaa ttgcagcccc catggcatga gattggggag ccgtatcgcc
    31141 aaaaccatcc gtattatgat gtgctgtaaa acctctagct ccatacattt tcttagcggt
    31201 tagtcttccc ggttctctca ttctttcgag catatcaaat aatggatatt ctacttctgg
    31261 taaatcacat ggacctacca tccaataatt catttgagta ttaatattaa tcgtatattt
    31321 agaaccccaa attggattta attcatcaca ccatattcct tgaagattgg caggtaaacc
    31381 attcggttga ctagacgata ttaacagata tcttccataa tgaaataaca agttagtcaa
    31441 gtagttacta tactttttag tgttttcaag aagtagattc gttggaatgc taagacaatc
    31501 tttactatag tctagtttaa aatcaactct attaaattgc tcctgatatt tttttacatg
    31561 ttcatctttt tctgtaaagt aatcaatact actaaattct ccctgaagag aagaaatatc
    31621 tatatttccc caataatccg tcattgattt gagataaaga aatacctctg tagcattccg
    31681 aataactatt gtctctccca atacacttac ttcaccatcc gtaaccttag aatgacatac
    31741 tactttaaac tgaacacctt ttctacctcc agcagaggcc gacattaaaa ttgtacttga
    31801 atccagttta gatacttcat cattaaaccg tttatttcta cccaaattaa tgtttaaatt
    31861 taatgtgttt tgaactgatg acactatacg gcaacataaa atattcttat taaaactcgt
    31921 aaaatattct ctttttattt gtaaattaca actattaggc tcaaacacaa cattagaaat
    31981 agctgtatct aaatctagct ctctttcata caatgaaaga gcacaagact gaatatctat
    32041 atgctcaatg taaagttccc caagtaattc atagtggctt tgatctcttg gggtagcaaa
    32101 cattgttaac tttatcaatt cttcggcttt ctgaatttct ccatctaaaa gatattcccg
    32161 aattttttta agatgcaata gtgagtctgg attatttcta tctgactttc ctctatacca
    32221 aatagtctca tcgtttagtt gaatacattc ttttgtagct gaaccataaa tcataccacc
    32281 taaatgaccg ttcccaatcg gcaaggcttc attccaattt gaggcagctt tcttatacca
    32341 taatttcact ctttacctct cttccaaaat ggaggtgata tcccaaatac cacctccaca
    32401 ctttctacta cttcaaaatt cctaaaacaa ctaggataac tccaatagcc ataacactaa
    32461 agattagtac aaccggattc tttccttttc taattaattt acacattaat aaagtcaaag
    32521 ccatagggat aaatcctgga attaattttg taatcatttc ttgaacagaa ataacaagtt
    32581 ccccctgctt aaattctaat ccaaaattaa taccaaccat tgatggaatc aaaccaccca
    32641 ctagtactag ccctaatgct gtcgccatac tcgtaacgcg attcaatgtt ccttttgtat
    32701 tattttcttg gataagacta gaacccttag tatacccata tttcaaaccg aaatatttaa
    32761 caggaatatt aataatatta aacaatatta aggcgataaa gatacctaaa gcaccgccgt
    32821 ctttagaata agacgcacca atactaaaac agataggaac tagtgtcagc cagaacaaac
    32881 tatctcctag accagccagt ggccccatca agccaacttt aataccagta attgaagctg
    32941 caccttcatt tccttcttgt tcttccatag cggaagtaac tccaagaata aatggtgccg
    33001 ctgtttgatg agtattgaaa aactcaaggt gacgtttcat tgcaggagaa gctgaatctt
    33061 tgtctgggta tagttttttc aatactggaa gaattgtata tagaaaacct aggttctgca
    33121 ttctctcata gttccatgaa gaaccataca taaaacttcg tttgaaaact tttttaagtt
    33181 caactttagt tactttatta ttcatcatag atcaagatcc tcctcaacat cactacttga
    33241 agttgtttct tgtggtttac ttccaatcat atcgtagaag tatgctaccg caataccaac
    33301 tagtgagatc ccaatggttg acattcctcc atacacagaa caaatgaatc caatcaacaa
    33361 gaatacccac atatttttct tgagcatcat atttaaaagc ataccaaaac caattgaagg
    33421 tagtaaagca cctgcagagt taagtccctg cataacgatt ggtggaacct tcgcaaacaa
    33481 gtctgccaca tattcccctc caagcataat agctaggaaa attggtacaa ttttaaataa
    33541 cgtgattaaa accaaacttg aataatgata aaaaccgatc tttgaataat ctccgttttt
    33601 agcatcatta tcagcttttt tcacaaaata aacatctaaa gtttttgcaa gaacatccaa
    33661 ctgttgggta gcaactgcaa ttggaactgc tatagcgata ccagcagttt ctccttgacc
    33721 agataaaata ccaaatgcag taccaataat cgcacctgaa atagtatctg gtggagtgta
    33781 acctccaata cctgttacac cgagccaagt taattcaaga gctgaaccaa taagaacacc
    33841 ttgggtgaaa tctcctaaga ctaagccaac cattgcactt gtaactaacg gacggtgaat
    33901 cataaataac ggtccattat agtcaatagt ggcaataatc ccaactaatg tcaccagtaa
    33961 tgcttgtgtg aatagcatat actgtacctc cttaaattat ttttataaaa atttttccaa
    34021 cattgtaact ttatcattag gaaccatttg aatttcaact ctcgttccct tatcaactat
    34081 tttcttaaaa taatatttgt cttcttcacc tagagctaca cctcccgtta ccttttcatt
    34141 ttcctccgtt ttactcatct gtcctacatt gaggtactcc aattttaaat ttccttcaat
    34201 agaatcatac acatcttttg gatttgtata tatcagcatt gttctctttt ttattggcac
    34261 agagtttaaa acttccacaa accgttttac actaaagaaa acaattttta aacctactgg
    34321 tgcagaaatc tttaaaatag attgtcgtgt tttatcttct gagatgcgat cattaacaat
    34381 gataacttgc tcaatatcat acttttttag ccacgtagtg acaacttgac catgtaccag
    34441 acggtcatca atacgaacaa actctataga cataaatctt cttcctcctc tacgttaagt
    34501 tgttgtttaa cattaaacaa actattttga gcattgtgaa caatttcttc taaattgatt
    34561 tttgaatcat aatttgatat taattccact aggagaggga tattaaaccc tgttacaata
    34621 tcaactgaat ccaaatttaa aaaccgtgac aaagcaacat tattaggact tcctccaatc
    34681 aagtcagtca aaacgataac ctcttgattt gagtctaaca gttcatttac ttgattttta
    34741 aaataatgtt caaactctac aatattctct ccaggcatca aacctaatgt cctaactcta
    34801 tcatttgttg tctcaccaac aaacatttct gcggtcatga gagctccgct agcaaaatta
    34861 ccatgactgg caactaaaat tcctctatta aacattttct ctttcaacaa ctactccttt
    34921 cttaaggata atattagcat aaagtgaagt ttctcctgta gcaacaatag cataagcttt
    34981 cttactacgt tcataaaagt cttctcttct aagataagta atcgttttaa gatctgtacc
    35041 atgaccttca atcatctgtc tataggtacc ccatatctta ggaatatcat cacccgaaac
    35101 aacgttcata aactgaattg aactatcgac gtaactatct aatggcatta aatacagaat
    35161 ggaatctaat aattctggaa tatttacacc atcacaacga attagcttat ttgcacatga
    35221 ggcagaagga taattcgcgt cagctaatac tatttcatct ccatgtccca tttccattaa
    35281 agtcttcaat aaatctggag aaatattttt cggtatatgt tttaacatta atatcctccc
    35341 tattttctct gaccgtatgt tttaaatttt tctgccatta aatccatctc ctcatcagga
    35401 agaactactg gctctccaaa attcttagct aaacaataaa tttttgcaca atattcaact
    35461 tcttcaacaa tattaaatgc attcaataaa ttttgtgcac ctgctaaaat tccatgattc
    35521 gctagtaaaa ctgctctacg accttccatt gctttagctg cattcacagc caattctttc
    35581 gtaccatatg ttgcatactc agctacccga acatctttcc ctgccactgc aatcatataa
    35641 tgactagccg gaagtggttc tctgagacaa gctaatactg ttgcataagt tgtatgagca
    35701 tggataattg catcgatatc atcacgagtt tgatattgaa tcaaatgcat ataccattcg
    35761 ctagatggca agcgttctcc ctctacaaca tttccattaa tatccatcac tacaatatcg
    35821 gattctttga tttcaaagaa atcaataccc gacggggtaa ttgccatcaa ttgtttttca
    35881 cgatcgaaaa cactgagatt cccacctgtt cctttcgtca aatctgtttc tactagcttc
    35941 ttgccatact taattaattc ttgttttaca tctgacattc ttgtcctcct catatcaaaa
    36001 cactaaatat ttttcaattc accaattatc cccccttctt gtacaaaact taagaagggg
    36061 gagggaggca aatttacaaa ctctcaatct ttttaattct tttgggagta ataactctct
    36121 aattgtagaa actcctcaat aacatggtga gcttcttcca tcccttttaa ttgtcccata
    36181 gctatgagct gcacaacaat attccccaca gctgtaccct cagtcgaacc tgtaagaacc
    36241 tctttaccag ttctatcagc aatcatttgg ttaaaataac tggctctagc acctcctcca
    36301 atcacatata tcctcttata aaccttatga gttagttctt ctagtaactc tatcgctttc
    36361 ctatacgttt cagctaggct ttcataaaca atcttaaata gttgtccatc tgtccactct
    36421 ctagtttcat gatgataagc tagatattct gtcaaagtct tgtgcatatc agattctgtt
    36481 gcaaattcag ttgattcagt atcaatcaga ggaagatttt ctttttcttt ctccaccatt
    36541 gtcctaatat catcaaaaga ataggctttc cctcttcgtt caaatgaacg tcttagttcc
    36601 tctatgatcc acaaccctgt acaattcttc agaaatgtaa tcactccatc tttaccgact
    36661 tcatttgtaa atccataact gaaggattcg gtagtaagaa tcggtgaagt aagttccact
    36721 ccaaccaaag accaagtacc tgatgaaata aataaactac cttctgtctt aggtactgag
    36781 acaatcgcgc ttgctgtatc atgactacaa acattcacaa caggaatatc gcctaaacca
    36841 tactcctttt ttatccttcc aagaacattt ccctctgaaa caatttcagg aagtaaagat
    36901 gaattcaatt caaatagttt taagatattc tgattccaat tttgactcct aggatcaaat
    36961 aattgagttg ttgaagcaat gcttttttct gtagcaaact tacctgtcaa gagataatta
    37021 aacaaatctg gcattaaaag aatcttattg gtcttataga aagagtcagg agattcttga
    37081 cgtgccttaa agagttgaaa caaggtattt atctccataa tctgatttcc tgtctctgaa
    37141 tacagttttt ctaattcagt catttcagat atttccttta acactccctt tgttctttca
    37201 tcacgataat gaacaggttg tgataacagc ttaccttcat tatcaatcag gccaaaatca
    37261 actccccatg tgtcaatacc gatagataaa atcttgtaac tagtattagc caagcggata
    37321 ctttcaagaa ttttagctag tagaaagtca acatcccaag ataaatgccc ttttactcta
    37381 ataggtagat tagaaaagcg atttatttct tccattacta gtttattttc agaaaggtaa
    37441 ccaacgattg ctcttccaga agtcgcacct aaatctattg ctaaaaccgc ttccattttt
    37501 cttctctctt cgtccttgat taagtttatt ataatcccca cattttattt tttcaatatg
    37561 tgaacgctta cttggataat gttcaaatgt taacccaata ttcataaaaa taattcaaat
    37621 tcctccaatt tgtgctataa tatagttgaa atgataaatt aggaggagct tatgataaaa
    37681 gatgaacgtg tacttgaatt gattgaaatt atcaaaaaga aaaaaagaat tgccgtaaaa
    37741 gagctggcag aaatcacttt ctccagcaca agtaccttac gtcgtgattt aattttctta
    37801 gaaaatcaag gtcttatcaa aagaaagcac ggatacgtga ccctgtcctc tatgaacaca
    37861 attgaacttt ctcatcaaat acgtgaagga gaaagtacta ggcaaaaaag actaatcgct
    37921 agtctcgcta aagactttat tcggtctggt atgtgtatct atctggattc cagtactact
    37981 gtctacgaac tctgtcccta tctttctgaa cttgataatt tgattatttt tacaaatggt
    38041 ttacatactg cacaaaccct atctgaaact gttaaagata gctccaaaat ctttatcaca
    38101 tctggcgagg tcaaacatca atcctgttcc gtggtcaact atgataagga aaattcttta
    38161 ttagatcatt ttaatatcga tttagcattt tgttcagcaa gaggtattga tgaccaatat
    38221 gtttatgaag cttctctcag ccaagctatt tcaaaaaaga atattattga caaagcccat
    38281 gaaaccatct tactgattga tagttctaaa ttttacaaga ctggattttt taaaattaat
    38341 cccctctcca aatacacaac ctttatttca gacaccgtgc cagatcaaaa attattagac
    38401 gcagtcgaat tatttgatgg agaatgggtt tctgatattc aatgaaaatc aaataggaag
    38461 ctagtctcag cttgctcaaa gtacagattt gaaaactgat gaagtcagct cgaaacactg
    38521 ttttgaggtt gtagatagaa ctgatgaagt cagtcacata tatacggaaa gacgaagctg
    38581 acatgatgtg aagagatttt cgaagagtat tcgttctgtc tgctgactga tttacaaata
    38641 ttcaccacat gacattattt tcttagcaac cccaaaaaca gaggctggac aaaaactcaa
    38701 tttcaggaga aaatggagta aaccttccca caataaaacg catagtatca agtttttgca
    38761 cacctgatat tatgcgtttt tctgatttta aagactttgt cgcctagacc ctatatttca
    38821 agaattaagt gaccttgatg atctaaattt attgtggtat actatttttg tcatcggtta
    38881 ccgattacgt tcctatgggt tcgtgagagg aggtgaaact aatgagcctt atcatagagc
    38941 tcgctcttac tattatagcg gatgttatag ctggaattat cttgtatttc gtctgcagat
    39001 ggctagatag taaggagtag accgactgac tagcctataa acacccgtta aatcgctaag
    39061 atacgtcaaa aaagccctta actacggcca tagttagggg ctttggtgtt ctaatgaacc
    39121 ttatcaatta actacatttt agcatataat ctacaatagt tcaagcatta agtgaggttg
    39181 atgatctaaa tttagtgtgg tatactattt ttgtcatcgg ttaccgatta cgttcctatg
    39241 ggttcgtgag aggaggtgaa actaatgagc cttataccag agcttgctct tactattata
    39301 gcagatgtta tagctggaat tatcttgtat ttcgtctgca aatggctaga tggtaagaag
    39361 tagaccgact gactagccta taaacaccca ttaaatcgct aagatacgtc aaaaaagccc
    39421 ttaactatgg cactagttag gggctttggt gttctaatga accttataca ctaactacat
    39481 tctagcatat aagcccagat atttcaagag ttttatttat tttttcaggt tcccttagtt
    39541 ctgaaaggtc tataatgaag ttagccatct agtatcaaaa aaccgactag ctcttatgaa
    39601 ctagtcgatt tctcatcaat gcgccaacat ttcttgggcg atttcttggc cagataggtt
    39661 atctgggtag taggttggcc agttgtccat ttcttcaaag agggcttctt ggcttgtgcc
    39721 tccaaagaag atatggaaat gttctgcctt aactggggca acattgtggt cactaaactg
    39781 aacatacttg aattgtccag cgtcagcatc tgtggcttca aagaggaaac gcacgccacg
    39841 attgcctttc ttgtaagtca aaattttctt accgacatac ttgtaagtgt atttcttgct
    39901 ttgtccacct tgaacaaatt ccatagtatt atcagtaatg ttaatcttag tcacatctgt
    39961 ctgatagcct tttgtatagt aagccttgta ctcagcctgg gtcatcttac cagttaactt
    40021 agccttgtag tcaaagactt ggtcaaacgt gccgtcttca aggaaaggat aaactgattg
    40081 ccagttacct gcatagtcac tcaaggtacg gtccttgaca gctgcatcct cgaagtaacc
    40141 attttggact gtcttggtat cctctgcctt ttcaggttcg attgctgggc cttcttggtc
    40201 tgttgtttgt ttcaaagcct tgaggttttt ctccatcacg gaaatgtagt tttctccagc
    40261 cttggtgtcc tcttctgtca gactttctaa aggattgagg acatcagttt tgacacctgc
    40321 ttcttttgaa agtgtgttag caagggcttg tgaggcattt tcttcaaaat agatataggc
    40381 gattttattt ttcttgacat actctgtcaa ttctgccaag cgagcagctg atggctctgc
    40441 atctggagaa agtcctgaga ttgcgacttg tttgagtcca tagtccaagg caagatagtt
    40501 aaaggctgcg tgttgagtca caaagctctt ttgttttgct tgagacaagc cttctgcgta
    40561 agccttatcc aaggcttgca atttttcgat ataggcagct gcattcttct caaaggtctc
    40621 ttttttatca ggataatctg ctgacaagct gtcgcggatg tgctctacta gtttaatggc
    40681 acgaactggt gataaccaaa catgggggtc aaactcatgg tgatgacctt cttctccatg
    40741 gtcatgatct ccctcttctt cctcgccacc tggcaagagc aacatatcgc ctgtcgcctt
    40801 gatggttttc acttttttct tatccaaggt atctagcaat ttaggtaccc atgtttccat
    40861 gttttcattt tcataaacaa aggtatctgc atcttggatt ttggcaactg ccttggcaga
    40921 tggttcgtat tcatgaggtt ctgtcccagc accgattagg agttctacat tagccgtatc
    40981 tcctgcgact tgcttggtaa attcatagac agggtaaaag gttgtcacga tattgagttt
    41041 accatctgcc tgtttttgat tggaacaagc cactaaaaac aaggcacata gactggctag
    41101 taataagcta atttttttca cgttcgtctc ctatttgata aaacgtctta ctaaactgat
    41161 tagtataaag acagttacaa aaataatggt aatacttgca cttgcaggtg tttctgcata
    41221 gtaggaaatg taaagtcctg ctaccattcc caaaaagcca atcgcactgg caagcagcat
    41281 aaccgattta aagtttttcc ccagacgcag ggcaatacta gctggcaaga ccataatggt
    41341 cgataccaga agagctcctg ctgcaggaat cataagggca atagccaccc ctgtcaccat
    41401 gttaaaaaga atggacatgg tacgaactgg caagccatcc acaaaggccg tatcttcgtc
    41461 aaaagttaag atatacatag gacgaagaaa gagaaaggtc aaaatcaaaa caaccgccgc
    41521 aatgacaaag agggaaatga cctgttcttc actgatagtc acgatcgaac caaagagata
    41581 ttggtccaaa ctcattgaac tcgagctttt acccttgctc atgacaatca gagaaacagc
    41641 cagacctgtt gacatgagga tagctgtccc gatttccata aagctcttgt aaaccgtacg
    41701 gagatactcc agaaagaccg ccgcaatcaa gacaatggca atagtagaaa cagttggaga
    41761 aatccccaaa accagaccaa aggctacacc tgaaagtgag acgtggctaa gggtatcact
    41821 catcaaactc tgacgacgca agatgaggaa ggttcccaat accggtgaga aaagactcat
    41881 agcaataacc gccaaaaagg cgcgttgtat aaagtcgtaa gataataaac taagcatggc
    41941 ccacctcctg gccattctca tgaacgttga aacaacgcca tggcgagtct tggttacgga
    42001 ctagatgaat attgcgatcc gcataatcct taacttcttc agggtcatgg gtaatcatca
    42061 aaacagcctt gccatgatga tgggcgctgt ggtgcatgag ttcgtaaaat tcatttttac
    42121 ttcctgcatc catccccgtt gtcggctcgt ctaggataaa cacatcaggg tcagaagcaa
    42181 acatacgcgc aattaccgct cgctgctttt gtcccccaga tagagacccc aagcgtttgt
    42241 ctcgatgttc ccacatgcca actgagtcca gactggcctt gatatgctcc tcatcatgag
    42301 cattcaaacg acggaaccag ccttttctcg gatagcgacc cgacttgaca aattcataga
    42361 ccgtacttgg aaaaccagca ttaaaactgg caatttgttg aggaagatag gctattctca
    42421 atttcttacc ttgcgtattt gtctttgaaa tagccacctt tccaatgcgt ggttgcagaa
    42481 ttccaagact agccttgatg agcgtcgtct tagccgctcc attttcccca gtcaaggtaa
    42541 caaattcccc actatcaaca caataattga tatgttcaag aacaggctcc ttatcataat
    42601 agaaggacaa atcctctacc gtaatatatc tcattatttg atttctccta ctaaagcagt
    42661 caaaaaccgc tgaatcactt tttgttcatt tggagtaaac tgagtcgcca cttgttcata
    42721 ggttaaaagt gtatgctcat ggtgatggtg gtgctcctca gcgattggac gagccaagtc
    42781 agtcaactga taaaaaatca cacgcgcatc tttagaatct ttagatgttt ccaacatccc
    42841 ttccttgacc aaagacttaa tggccttggt aactgccgcc tgactgacat tgagacgacg
    42901 ggccaattct gaatttgtta aagattcctc tgacaagagc ataaggatat gctcctgagt
    42961 attggtcagg gccacctcgc tagtgcaatg acctattagg atttcatgct gattttccgc
    43021 ctgcaaaatc acctcattca aaaaagcatt gatatccttt gctagctgtc tcatatctga
    43081 ctcctttcct tttagacttc tcttttttaa gagaaaaata ctattctttg acattttgtt
    43141 taccagttaa ttatatcaca agcaaaaaaa gagtcaagaa aaaacgtgaa aactagtttc
    43201 attcttgaac tcttctatat tatattatct attgaaattc tttgacatct ccatcataag
    43261 tcgcccaatc tttgctgaaa aagcgctcat tcagatggta agtcggagct ggtgtgggat
    43321 tggataggaa aggatcaact gccttgtcaa aagccaacca acccaaccaa ccaaggtgaa
    43381 tggtgtcctt cataaagaaa ggctccccgc cgtccttaga aaaatctgct atattggtaa
    43441 aaccttgact ttctaactgg tagcgaatct tctgcaccgt ttgttggtac atatcctctc
    43501 gtagaccagc atagtccatc cattttttat taacaggtgg aatgataaaa atcgggttta
    43561 ccttagattt agaaaactgt gttaaaacca actgcaagtc attatactct ggcgacttga
    43621 gataggtaaa gcttttctga gaatccttta atttcttcaa atccttcttg atctgctcat
    43681 tatagaaata attttccatt cccatctcat tattggaagt atttttttca gcatctgctt
    43741 tgacaacatc ttctattgct tgataagaaa actggtctgg caagattttt aaatacttag
    43801 ctacatgctt atcgtagtta acatagcctc taaccgaaaa ctgaccaaaa aaggaggctt
    43861 ggcgttcatt aaaacgagcc aataattcaa tcatttcatt gtctgctgtc gacaattctc
    43921 ctttacttgc caacttctga accaggtcct tcatagctac gtttgggaac tgttgcagta
    43981 agcgagtcgc tgcatattga ctagcctgat ccccagattg atgtttcaga aaactagtca
    44041 actggtctcc attaaaatac tgctggaagg ctgctggatc atagccattt ttactgaacc
    44101 actgaggtga gataacatac acaacttgtt tattctccag ctgtggtaac atctgttgca
    44161 ttccaaaata ttggttaagc gatgcagctc ccccctgtcc taaaagataa ggacggtagg
    44221 aacgattgta tttctcagct aataccgcag gatgagcacc gtcaaaacga agccattcac
    44281 tagagccaaa gaagggaaca aaacgcacat ttggatcaga tagtgctctg actttttgac
    44341 ttcgctcctt aaaactatcg atagtagtag ccactgctga acgcttttca gctcctagat
    44401 tatgatgcat ctcagtagga taaaagaaaa tgagcagaaa aaccaacaaa ccagcgatca
    44461 agaccggtcc gaagatcatc cataagcgtt taagcatttt gtagctccac aataccagct
    44521 atgattttat tagctgtatt ccagtcgtca cgaccaaact ctgttacagg gacacgaatg
    44581 tcaaaacggt tctcaatctc cacaatcaac tcaaccgttc ccatactatc caagacacct
    44641 gcatcaaaaa gatcttcatc catcatgtca gaaacatctt ccataaacaa ctcatcaata
    44701 atttcaataa cttctgattt gatatccata ttttatttcc ttttattttt taaaccatag
    44761 attattcaag aatccagaaa agattaagaa tgacaacatg acaacatgga aagtgacaac
    44821 catgccaagc aactgaatcc agcgattctc aggtagggca gccttccctg cttttttccg
    44881 ttccttattg agcgtttttt tcttgcgaac ccaggcatca ttgatgacca agcctagtcc
    44941 atgaaagagt ccataggcga tatagtacca ggtcacacca tgccaaaatc ccataatcag
    45001 catatttaca atgtaagcca tgcttgaggt tacattacga tttttaaaga ctttctttct
    45061 ggttaacacc atcaccattc gcataaagac aaagtcacgg aaccagaagg acagactcat
    45121 atgccagcga ttccaaaact cctttaaatc ccttgataaa aagggcttgt taaagttgat
    45181 agggctacgg attcccatca agtttgagat ggccaaagca aacatagaat aacctgcaaa
    45241 gtcaaagaag agctccagac caaaagtata cataactgcc aaggcataga gattaaagaa
    45301 gccacctgac tgcaaggcta aattcttcag aggaggtagt aaggtctctc ctaaaacatg
    45361 agctaggata aacttataca aaaagcccca catgatatag cggacagatt catccagcat
    45421 atccatcaac tcatctcgct caggaatggt ctgataattt tcattaaatc gcttaaagcg
    45481 atcgattgga ccactcgaga aagttggcat gaagagaagg aaacggagga attcccagag
    45541 ggtaaaatcc ttaatcactc catctctcag ctcgatgata atcccaaccg aacgaaaggt
    45601 caggtaagaa attcccaaga acccaagcaa agactgcgtt ccattgatag ctggttgcac
    45661 cttgacaaag ataatcggaa gtagggacag aaaactaact aagtagaaga cccacttgcc
    45721 atccttgctt tttcgataat gcttgtagaa aagcaggagc aatatttccc agcaaaggta
    45781 aatacccaag gcagctagtt gattggtctt tccacccacc aacatggtga caataaagaa
    45841 gagacttacc aacacttcat accaggcaaa gcgtttcttg aaaaagaggc ctataaagat
    45901 gggcaaggtt gcagcaatca cataaacaaa atactgagga ttgccatatg gctctaaatg
    45961 aggaagctgt tgaaaaaact ccatcatctc ttattcacct cgttaatcaa tcctttgatg
    46021 tcaatctttc catttggagt tagtggcaaa ctgtctcggt aaaggaattt agatggcatc
    46081 atgtaggaca tcatgatgtc tgtcaggtct tccttgatgg ccttggtaat atcgatatct
    46141 cgctcaaact gctcacgaac accgtctttt aagatgacat aagccaatag attttgtacc
    46201 ttatggtcct tgttatagcg cggtactgcg acagcagatt cgataaagcg agacttgttg
    46261 aggttttgag agacatcttc taactcaatg cggtaaccgt taaacttaat ctggaagtcc
    46321 atgcgtccgc cgtaaagaag caagccctca tctgtcatgg ttcccacatc gcctgtgtga
    46381 taggctggca gaccttcaaa ctcaaagaag gcttctgctg ttttttcagg attgttcata
    46441 taaccttttg aaacagctgg cccagaaaca atgatttctc cctgttcgcc atttggcagt
    46501 ttatttcctt cctcgtcaat gataaaggtt ggagaatcag ccttggtata gccgattggt
    46561 aggcgtttga gagtcgctaa catctcgtct gtcacggcaa ctgctgacag agctactgtc
    46621 gcttctgttg ggccgtaagc attgatgata cgggcatttg ggaaacgctc gcgcagtttt
    46681 tgagctgttt tgaccgtcaa ttcttcacca tcaaagtaga aatgcgtgat tccaggcatt
    46741 ttctcactgt tgaagtattc agacaacatg gccatatctg caaaggatgg tgttgatgtc
    46801 cagatagcga ttggcaatga aaagatagcc gcaaagagtt gcttaaagtc ctgagtgatg
    46861 actgaaggaa gagtgaaaag cgtaccacca agtgccaagg tcggtgccca atacatgaca
    46921 gacaagtcaa aagaataagg tggctgtgcc agcatttgcg gacgactcgg tgtcgcaaat
    46981 tccttatccg taatcatcca gtttgtaaag ctgaggagat tatcatgtga aatctgcact
    47041 cccttaggct taccagtcgt accagaagta aagataatgt agtaattatc atctcccttg
    47101 actggatgcg tgatttcata gttgttccct tgggcaaagg cttcttgaac ctgagctaga
    47161 tttatcattg gtgtagaaac ctgctccaag ggaaaggctg aaatggcaat aatcaagctt
    47221 ggctctgcta cttctaaaat agctgaaact cgctccaagg ccgaatggct atcaattgga
    47281 atgtaggcat gacctgactt agtcagcgct acaaaggttg ccaacatttc atattcttgg
    47341 ccaccaaaaa caaccacagg agacttctca ggcaagccta gttggtcaat gactgcagcc
    47401 aaactatccg aatcagcctt taaatcgcca taagtgtgtt cctgccccaa aacattatag
    47461 acaggatagc taggctgtgt ctgagcaaaa tgctcaatgg tttcaatcat atctgctatt
    47521 ggtttatttg acacaatagg gattctcctt caagttaaaa ttcattatag ataaagcttc
    47581 cttgaccctg accaagatag ctaaagaagt aaagcagccc tagaaagata agaaaataca
    47641 aggctgtccg accaagaaag aggtacaatt cttttctctg tttcatcaag aaaaaccatt
    47701 catttctgta atttttcgct aaaataagag tgattcttac tagcttattt ttctaccatt
    47761 gtaccacttt atatagtatc ttttcaattg tttaccgtat gtttccaata gatttcagct
    47821 tattttaagg attatacagt ttttctatgt atattttcaa atagagtgat cctgcttcaa
    47881 aactccattt caggagacaa tgaagtaaat cttcccataa taaaacacac aatatcaagt
    47941 tttttcaaca cctgatacta tgcgcttttc tgatttttaa agacttttta accactctct
    48001 catttaaaat aatctcgtct gatataaatt aaaatagctt ctatcatcag acaaatggct
    48061 gatagccaaa aactgatgct aataccaaaa ctctcagtaa tatagctcat tagcaaaaca
    48121 aatactgaaa atgctaatgt agaaatcact tcaagaacgg aatagacatt aactaaatga
    48181 ttttcctcta ctgtttcctg aagaaataca ctttcaggaa cttcttttag ttgcgataac
    48241 ataccaacta aagctgaaaa taataaaaac atctgtgcgt ttggaaaata tagaatagtc
    48301 agtgtcacta ttgccatagc tacaagagga aaaagaatac tttcccattt agcagcaagg
    48361 aacttttcag atagcctaaa agcaattaag ccactaatta taataccaat agagtatgct
    48421 gtattagaat atccccagta actttccgtt ttatttaata actccgttac aaaaacaagt
    48481 ataatggaag aaacccaaat cgtatttgaa aaaatttcca ataaatttgc tgatacaaaa
    48541 agtcttaatc taggatttct agcaactaac ttccaacctt tgagcaaaat ttcaagatta
    48601 gtttctgact ctaacacctc cacttcagcg ttaggaagaa ataacatcag aaagctagaa
    48661 atgatataca agactaaatt gatacacgtg gtaggtaaca gaccaattgt tgcaaacaag
    48721 agtccaccta atccccaacc tatcaattga acagcttcac cagtcattga taaggctgaa
    48781 ttagccttac ccaaatcggt cgcatagcgt ggcacaatag cataggaaac gggtgctgca
    48841 aaaccatcta gtatggaaat tgcaacaaca aatagatagg tcaccaaagg cgctacggat
    48901 tgcattacgg taaacattcc taccagtatc gccaataata tagtctttcc aaattgagat
    48961 aaagataaaa ccctatttag cgctaacctt ttagtaacca acggaactaa aagactcgca
    49021 acaaaagagg atattcctat taagatagga actagtgatg tggcaattac tgattttgaa
    49081 ataatgtata tgttagcaat gattgttact ctaaagaaaa tatctgctaa atttgcaaat
    49141 aattgagaga ctaacaactt gacaaatgaa ttagacatgt agcgctcccc ctttagttac
    49201 aaactttgga attaaatttg atttttaata ttttagcata aaatagcaga aaacaaaagt
    49261 gaggtttttt acatgaaaaa acaaaaacta ttgcctttat tattcctaat tttaggagga
    49321 attatgatta tcgttgttgg ctagtactaa gaagttagtt agtagaataa ttacatcttc
    49381 aatcgaaaaa gagactggaa aaagtcttaa aaatcagaaa aacgctcaaa tcctttggcg
    49441 ctctaagctt ttctaatgat agatttagat agtcaaaaaa atatctgaaa agttcccagg
    49501 atcgtcgtct cagcatcaaa aatacgtgaa atttgcataa ttaaaataaa tttcagggga
    49561 gttaatcgag taggggataa tctctagccc ctctcacacc accgtacgtg ccgttcggca
    49621 tacagcggtt caactaactt ttaacgcatg tcgttcaagg taataatcca aacacgaaac
    49681 cagtccacgt ttttccagga ctggttttga tatagcacgt ttaagtaccg acttctgagc
    49741 tactaattga taatggtcgc cccagccaga taccttatct gctatccatt taggaactcc
    49801 taacttaagc aatccccata atcgtctcga tttcttcttc cattgcttcc agataatcac
    49861 tcgtaggcga gtacgcaagc gctcatctat gctggcgact atacttttca tatttcccaa
    49921 tgagaaatag tttatccatc ctcgaataga caaattcagt tgctcaatac gtcttgttag
    49981 gtctatactc catttcctct gtgttagttt cttcaattta agcttaaatc tccgaacact
    50041 atcttgatgt ggacgacttt tccaaccatc tgatgatttc cagaacccaa aacctagata
    50101 tttcaactct cttggtctgg taatcttagt cttggtcatg tttactttca aacctagccg
    50161 tttctcaata aaacgactga ctgaatacat cacacgctta gcggctgcct cgcttccgac
    50221 cgtatcacac aatcatctgc gtagcgcaca aatcgaagtc ccctcttttc taattccttg
    50281 tccaattcat taagcatgat attggataag agaggagata aatttcctcc ctgtggtgta
    50341 ccaactagtg ttttataacg ttgaccatta atgataacac ctgaatgaag atacttacga
    50401 atcaaggatt ccgtatctcc gtcttcgata atgttatgta ctaaggacat caatctatct
    50461 tgaggaactg tatcgaaaaa tttctctagg tctatatcca ctatccactc atagccgtca
    50521 tttaagtatt ctaagagctt catgatggct ttttcacatg acctatttgg tctgaaacca
    50581 taactcgtat ctgagaaatg gggttcacaa atggggctca tgacttggac aatggcctgt
    50641 tgaatcattc tatccataac tgttgaaatt cctagttgac ggatgcctcc gtctggttta
    50701 ggtatctcaa ctttaagaac tggttgaggc ttatattttc tctgttttat cagttcctta
    50761 gtcaagcgcc agttttgtct gagataatta tccatctctt cgatagtcat tccatcaatc
    50821 ccagctgagc ctttattgga ttttacttga ttgtaggctt ccagcatatt ttcgcgtgat
    50881 aatatcttat ctagcagttt tgacatgtgc gtattccttt cttgttttgg tgcctgaggg
    50941 acatcttata ttggtgaacc ttcatctagt cattacgtgt caaagtccag ttctatcaga
    51001 ccactcattt tacagacaca agtgaagtag gattacttcg atctgtcgtt ttctctttct
    51061 agcgacagac ctcaaacagt ctctccccag actgtttgag tattcacccc ttcgctccac
    51121 ttccactaca gaagtttcct cactactatg ggctcggctg acttctcatg attcgttgtt
    51181 actacgcttt cagcgctcat gaaacctcac gggataagtc gtacatcttt cctcgtttat
    51241 acaagatatg aggacgttaa aaggttacag tgaaaatagg aaatctgacg cagagtcttt
    51301 agactctaga aagatttatc tttttcacac aaaccttagt ccgaattcaa ttactctcgt
    51361 gatttacaca tataggttac gactaccttt ttggacttta gagtttgaag cctccttatc
    51421 cgctatatac gccttactat cacgttcctg ttcgtagagc cacgatttcg ctatcccttc
    51481 ctctgacgat tcttatttcc tgcgtcagac ttaaaacggt ctatccccag accgttttaa
    51541 tccgctacct cacgatagtc aggcttggga atcgctattg ggttcaccg
//
LOCUS       DAVKMJ010000010        51059 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000010 DAVKMJ010000000
VERSION     DAVKMJ010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51059
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.010"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            145..837
                     /locus_tag="VW348_000583"
     CDS             145..837
                     /locus_tag="VW348_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU9745530.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(940..2585)
                     /locus_tag="VW348_000584"
                     /pseudo
     CDS             complement(940..2585)
                     /locus_tag="VW348_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(2575..3666)
                     /locus_tag="VW348_000585"
                     /pseudo
     CDS             complement(2575..3666)
                     /locus_tag="VW348_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289362.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(3679..4800)
                     /locus_tag="VW348_000586"
                     /pseudo
     CDS             complement(3679..4800)
                     /locus_tag="VW348_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(5017..5214)
                     /locus_tag="VW348_000587"
     CDS             complement(5017..5214)
                     /locus_tag="VW348_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU9745531.1"
                     /translation="MTLNEYILQYRLKQAIDKMAESPNSPLSAISDQVGFSDYKYFAK
                     VFKKYLHISPKKLKSLGRIVK"
     gene            complement(5289..6065)
                     /locus_tag="VW348_000588"
     CDS             complement(5289..6065)
                     /locus_tag="VW348_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEU9745532.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            6187..6933
                     /locus_tag="VW348_000589"
     CDS             6187..6933
                     /locus_tag="VW348_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9745533.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            6946..7926
                     /locus_tag="VW348_000590"
     CDS             6946..7926
                     /locus_tag="VW348_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEU9745534.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            8121..8441
                     /locus_tag="VW348_000591"
     CDS             8121..8441
                     /locus_tag="VW348_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9745535.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            8487..8795
                     /locus_tag="VW348_000592"
     CDS             8487..8795
                     /locus_tag="VW348_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9745536.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            8812..10110
                     /locus_tag="VW348_000593"
     CDS             8812..10110
                     /locus_tag="VW348_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9745537.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLAMSTMVYFPFFKIQDRLACQNEIKQS"
     gene            10261..12699
                     /locus_tag="VW348_000594"
     CDS             10261..12699
                     /locus_tag="VW348_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEU9745538.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            12718..13386
                     /locus_tag="VW348_000595"
     CDS             12718..13386
                     /locus_tag="VW348_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEU9745539.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHKIRRQAGDDIFIKVPVTPAGLRAIKALK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            13404..14492
                     /locus_tag="VW348_000596"
     CDS             13404..14492
                     /locus_tag="VW348_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEU9745540.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            14947..17448
                     /locus_tag="VW348_000597"
     CDS             14947..17448
                     /locus_tag="VW348_000597"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEU9745541.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            17642..18337
                     /locus_tag="VW348_000598"
     CDS             17642..18337
                     /locus_tag="VW348_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9745542.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            18349..18765
                     /locus_tag="VW348_000599"
     CDS             18349..18765
                     /locus_tag="VW348_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9745543.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(19580..19672)
                     /locus_tag="VW348_000600"
     CDS             complement(19580..19672)
                     /locus_tag="VW348_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEU9745544.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            19833..20804
                     /gene="ruvB"
                     /locus_tag="VW348_000601"
     CDS             19833..20804
                     /gene="ruvB"
                     /locus_tag="VW348_000601"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEU9745545.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            20785..21357
                     /locus_tag="VW348_000602"
     CDS             20785..21357
                     /locus_tag="VW348_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEU9745546.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            21588..22346
                     /locus_tag="VW348_000603"
     CDS             21588..22346
                     /locus_tag="VW348_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEU9745547.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            22355..23158
                     /locus_tag="VW348_000604"
     CDS             22355..23158
                     /locus_tag="VW348_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEU9745548.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            23180..24439
                     /gene="rseP"
                     /locus_tag="VW348_000605"
     CDS             23180..24439
                     /gene="rseP"
                     /locus_tag="VW348_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEU9745549.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPKDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            24452..26305
                     /locus_tag="VW348_000606"
     CDS             24452..26305
                     /locus_tag="VW348_000606"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEU9745550.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTSEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            26404..27783
                     /gene="bglA"
                     /locus_tag="VW348_000607"
     CDS             26404..27783
                     /gene="bglA"
                     /locus_tag="VW348_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU9745551.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEHYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            27976..29784
                     /gene="glmS"
                     /locus_tag="VW348_000608"
     CDS             27976..29784
                     /gene="glmS"
                     /locus_tag="VW348_000608"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEU9745552.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNSRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVIDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLSLLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGFDVDKPRNLAKSVTVE"
     gene            complement(29922..29999)
                     /locus_tag="VW348_000609"
                     /pseudo
     CDS             complement(29922..29999)
                     /locus_tag="VW348_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            30056..31105
                     /locus_tag="VW348_000610"
     CDS             30056..31105
                     /locus_tag="VW348_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEU9745553.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLALLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(31205..35041)
                     /gene="spuA"
                     /locus_tag="VW348_000611"
     CDS             complement(31205..35041)
                     /gene="spuA"
                     /locus_tag="VW348_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEU9745554.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNKSDISSLGNANASLEKTEEKPATEPT
                     TPAASPADPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQ
                     GLWTWDDVEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNL
                     TGDKSVEKLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVK
                     NPSSAQWPDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFT
                     DLKNHSQIFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKH
                     SNITNHLGNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDE
                     TYSYDGKLGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTW
                     KQTLDSTNKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSNDAKIDDAHKVA
                     KAAFVDPAKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEA
                     FIEKLDYLKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSL
                     TGMYSSDPKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFM
                     DADGTPRTSFGGGRLGTTHHMTKRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEA
                     YKAARALNPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGY
                     PNEGQPAFITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSI
                     KKDPSKAENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDK
                     VPNKSHLLRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKG
                     LIALRQSTDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVN
                     ADEKAREFNLGTAFAHLRNAEVLADENQAGPVGIANPKGLEWTEKGLKLNALTATVLR
                     VSQNGTSHESTAEEKPDSTPSKPEHQDPAPEARPDSTKPDAKVADAENKPSQATADSQ
                     AEQPAQEAQASSVKEAVQNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGISL
                     LALLGLGFLLKNKKEN"
     gene            35458..35871
                     /gene="rpsL"
                     /locus_tag="VW348_000612"
     CDS             35458..35871
                     /gene="rpsL"
                     /locus_tag="VW348_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEU9745555.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            35891..36361
                     /gene="rpsG"
                     /locus_tag="VW348_000613"
     CDS             35891..36361
                     /gene="rpsG"
                     /locus_tag="VW348_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEU9745556.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            36786..38867
                     /gene="fusA"
                     /locus_tag="VW348_000614"
     CDS             36786..38867
                     /gene="fusA"
                     /locus_tag="VW348_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEU9745557.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            38971..43362
                     /locus_tag="VW348_000615"
     CDS             38971..43362
                     /locus_tag="VW348_000615"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEU9745558.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREVFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYCSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            43464..43727
                     /locus_tag="VW348_000616"
     CDS             43464..43727
                     /locus_tag="VW348_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEU9745559.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            43720..43998
                     /locus_tag="VW348_000617"
     CDS             43720..43998
                     /locus_tag="VW348_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEU9745560.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            44019..44171
                     /locus_tag="VW348_000618"
     CDS             44019..44171
                     /locus_tag="VW348_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745561.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALREK"
     gene            44193..45434
                     /locus_tag="VW348_000619"
     CDS             44193..45434
                     /locus_tag="VW348_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEU9745562.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEGFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            45444..45674
                     /locus_tag="VW348_000620"
     CDS             45444..45674
                     /locus_tag="VW348_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU9745563.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAVLGAMIVLAIFWRRGS"
     gene            45897..46619
                     /locus_tag="VW348_000621"
     CDS             45897..46619
                     /locus_tag="VW348_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU9745564.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            46836..48170
                     /gene="pepC"
                     /locus_tag="VW348_000622"
     CDS             46836..48170
                     /gene="pepC"
                     /locus_tag="VW348_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEU9745565.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQVTVQTKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(48226..49137)
                     /locus_tag="VW348_000623"
     CDS             complement(48226..49137)
                     /locus_tag="VW348_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9745566.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(49161..49964)
                     /locus_tag="VW348_000624"
     CDS             complement(49161..49964)
                     /locus_tag="VW348_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEU9745567.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(49992..50981)
                     /gene="manX"
                     /locus_tag="VW348_000625"
     CDS             complement(49992..50981)
                     /gene="manX"
                     /locus_tag="VW348_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEU9745568.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
BASE COUNT        15097 a         9216 c        11483 g        15263 t
ORIGIN      
        1 attagtttga atttgatttt catctaatat ctttatttaa tgaactccta aactttttca
       61 taataatctc cttcaaaagt cgcctgtatg ggtggctttt attttatcat tcatgatata
      121 atagaagcaa acggaggacg gaaaatggta aaagtacgat tgtatttggt acgtcatggc
      181 aagaccatgt ttaacacgat tggtcgcgcg caaggttgga gcgatactcc cttaactgct
      241 gaaggtgaac gagggattca agagttagga attggtttgc gagaatctga tctacagttt
      301 gagcgcgctt attcgagtga ttctggtcgt accattcaga ccatgggaat tatccttgaa
      361 gaacttggct tgcaggggaa aatcccttat cgcatggaca agcgtatcag agaatggtgt
      421 ttcggtagtt ttgatggagc ctatgatggc gatcttttca tgggcattat tcctcgtatc
      481 tttaatgtgg accacgttca ccaattgtct tatgctgaac tggctgaggg cttggtagag
      541 gtcgatacag ctggttgggc tgaaggctgg gaaaaactca gtggccgaat caaggaaggc
      601 tttgaaatga ttgcaaaaga aatggaagat caaggtggag gtaacgccct tgttgtcagc
      661 catggaatga ctattggaac cattgtttat ctgattaatg gcatgcatcc gcatggtcta
      721 gataatggta gcgtgacgat tcttgaatat gaggacggtc agtttagggt tgaagttgtc
      781 ggtgaccgta gttaccgaga gctaggacgt gagaagatgg aagaaggctc tatttaatca
      841 gtctagactt gcttgccatg agctagggat ttgataagaa tatcaagata agaaaaaaca
      901 gccgagggta ctcctttcgg ctgtttttga tgtggaaaac taaagtgtaa tgctattgct
      961 tttagagatt ttcataaaca agagcaagga acctactgtt agaacagtca ggatagttga
     1021 caaggctgcg gctacaccgt aatttcctct gagaacctct gtataaatag ctacagtcat
     1081 tgttcttgtt ttgacattgt agaggaggat agaagtagag agttttgaaa tcattatgac
     1141 ctaagataag atggctccag aaatgatacc agatagcatc attggagttg taatcttagc
     1201 aaaggtattg agacgactac ttcctaagct ttcagcagct tcttcaatac ttggtgctat
     1261 ttgttgtaag ctagcaacag atgagcgaat agtataaggt aatcttctga cagatagaga
     1321 cataatcaag atgaaagcag tccctgtaat cataagaaat ccacttccaa atagaccagt
     1381 attgaaggaa gaaatgaagg caatccctag aacggttcct ggtacaatat aaggtaccat
     1441 actgaggctg tcaattaagt ttgtaaacaa attccgtttt ctaacggcta ggtaggagat
     1501 aaatgtcgca aatagaacaa ctagaactaa ggcaatcaaa gggatacgaa tggtattgaa
     1561 aatagcagat cccatacgat tgaaagctac cttgtaactg tttggagaat aacctttaac
     1621 agataccata cctgatgttt ttaggaaaga ggtataaatt aagtagattt gaggtaaaac
     1681 agagataaag ataattccgt agactgttgc ataaatggca gctatttttc cttttgtagt
     1741 ttttttaggc tcaattggat ggagcagatt catgctgaaa ctgtagcggt ttgcaatgtg
     1801 tttttggata aggaaaattg ccaagacaat gataatcgcc ataattgcaa aagcagaatt
     1861 tcctccaacc tcgctaataa attgggtata aatcaggaca gggaaggtcc gatatccttc
     1921 gccaatcaac ataggcgttc caaagtctga gaatgctctc ataaatacaa gcaaggagct
     1981 gctagtaagg ttggaactag gagaggtaaa acaaccgtta cgataggttt aaatccgaag
     2041 gaccccatgc tttcagctgc ttcaagtaga gaattgtcaa tactgttcat tgttccagca
     2101 acatatagaa ataccagtgg gaatagttgc agtgtaaaga caagtacaat tcctttgaat
     2161 ccataaatat cgatagctgg aagatgaagg gcatttgtca aaaatttagt gatgacccca
     2221 tttcgtccta gcaagagaac ccaggagtag gctcctacga aaggagctga catggaagca
     2281 atgataatca atatttgtag aaatttcttc cccttgaagt catacataga gaagagataa
     2341 gctaataggg ttcctacaac taaggaagtg acagtagcgg taatggaaac cttgaaactg
     2401 ttgactagtg tctcagagta gtagacttta ctaaagaaag tgacaaaatt agctagtgag
     2461 aattgtcctt catgtataag tgcttgcttg agcacggtaa cgataggata aacgagaaag
     2521 acaagatagg taagaaagat gaagaaagag gaggttgtcc aaatatttag ttttttacat
     2581 tccatggttg actcctttta tcaggttttg ggaaccatct gcagaaaaga tgtttaattt
     2641 ttgcgtattg attcgtagac gaatacgatt gcctttttgt agttcttctt caaaagttga
     2701 ttcttcacta acttgaattt ttgaggcaaa acctgtctca atgaaatact ccgtatttag
     2761 tccaagatag acgctatcgc taatagttcc ttcaatatct ccagattcat ctttgataaa
     2821 ctcttcggga cgaatgctta catgaatagc ttgctcctca acctgatcaa gagctggcat
     2881 tcgaagggca tagccatctg aaaagacgat ataagcgccg tcgctccgtt tttcaagatt
     2941 agtagggata atatttgtgc gtccgataaa ggttgccaca aactcattag ctggtttatg
     3001 atagagttct tttggtcggc cgatttgttg gatcacccca tctttcataa cagcaatttg
     3061 gtctgaaata gccatggctt cttcttggtc gtgggttaca taaacagttg taattcccac
     3121 ttcgtgttgg atttctcgga tggcttgacg catatccaag cgaagtttgg cctccagatt
     3181 actaagtggc tcgtccatga ggagaacact tggattaacc gctaaggcgc atgccaaggt
     3241 gacacgttgt tgttgtccac cactgagttt atcgggcttt caatccgcat attgagcaat
     3301 ttgcatgagt tcaagatact tgttggtctg ttgaatcaat tcttcttttg gaaccttctt
     3361 ttgcataaga ccaaaagcaa cgttgtctcg gacagtcaaa tgtgggaaaa tagcgtagtt
     3421 ttggaaaacc agcccgatat tgcgtttgct gggttccata ttattgattt ttgtatcatc
     3481 gaagtaaaat tctccatctt tgatactgtt gaaacctgca atcatacgaa gaagggtcgt
     3541 tttcccacat cctgaagctc caagaagggt aaagagactt ccttttggaa ttgtaatgtt
     3601 caaattctca ataacaggga catcgtggta gatttttttg gcgttaataa tttcgatctc
     3661 actcatagtg aacctctttt actgtttaga ttggatatct gtaaagactt cgttgtattt
     3721 cttaacgata tctgatttat tcttgatgac ataatcataa tcttcagtga gtgttttgat
     3781 tttgtcaatt ggtttcatgt tttcgcttgt tttagcattt ttacgaacag gacggttagt
     3841 agtggttgta ccaagtgtat cttgtacttc ttgagagata ataaaatcga taaatttctt
     3901 ggcattttcc atatttttag cttttttaac gatagcagca ctagcaggta ggaagacggt
     3961 tccttctttt ggatagacta ctttaatgtt agctccgtca tttaagagtt taactgctgg
     4021 atcctcataa gagagaccaa cagccatttc tccatcaacg actgctttat agacaccaga
     4081 tgaacttgaa ccgattttat agtgtattga aactagaata gtacacctct acttctaaaa
     4141 cattgttaga aatcgatttg actgtcctga ttaatttgtc ctgttcttat ttcattttac
     4201 tataccatca ataagtgtga aaagatcttt tacataagac caagccttat catctttgta
     4261 accaccttga gcttgtagca tatttgttaa ttgagcaaag gcgctagaag agtttgctgg
     4321 gtcagcagtt gcgatttttc cttttagttc aggtttgaga aggtcgctat atccttcgat
     4381 gttcatgcct ttagttaaat cagggtggac gattaaaaca ctaccatcta gtgtataagg
     4441 agtagagaag ccagttgtgt tttgatattc tttgataaca ttatcatttt cttttgaaat
     4501 atagttttca aagagttctc cgtgggtagc atattgtgta taagaaccac caaagataac
     4561 atcagctaca ggaacttctt tttctgactc tagttttttg aaaagttctc cagtaccagc
     4621 ttgaatcagt tctattttga taccatattt ttcttcaaag gcaggaatag ttgctccaat
     4681 taagccttct gagtttggtg aataaacgac tagcgaacca ccgtctcctt tatcagatga
     4741 actgtcatcg gcagattcat tagaagaaca agcagcataa tacatccatt tctttttcat
     4801 gatggatatc tccgttgtgt tatttaagtt tattttaaaa caatgtaagc gtttttaaaa
     4861 cctacaattc tattctatag tgtattgaat ctataacagt acactttgac tgctaaaata
     4921 tttctataaa ttaatttgac tttcctgata gagatgttca catcttattt caattcacta
     4981 tattagagta aaattctcta caaaaagaag aatagcctat ttgactattc ttccgagtga
     5041 tttcaatttc tttggggaaa tatggagata ctttttaaat actttggcaa aatatttata
     5101 gtctgaaaat ccaacttggt cagagatagc gcttaaaggg gagttgggag attcagccat
     5161 cttatctata gcttgtttca ggcgatattg taagatatat tcatttagag tcatggggaa
     5221 gtcttctttg ataaccttat atagatgctt gttatctgca aatagctaga gcatttcaag
     5281 gaaataaact agaaataaca attaatatgg tggttcagaa ataccttttg ataatcaata
     5341 agatcttcag gatgaagtgc gttgattcca tccatttcat atttccgatt taataaacga
     5401 tatttgtttt caccaaattg atgaaaaggg agtagttgaa cttggtcgat atttaatgag
     5461 ttaaatagag tagcgaattt ttctgcatcc tctaaactat tgttaaaatt aggaataact
     5521 gggattctta aaacgatagt tttattttga gaaaaagcat aatgaatgtt tttaataatc
     5581 atttgattaa aaaccccagt cactttttta tgttttatag aattataatg ttttaggtct
     5641 gtgtagataa aatccacata ttgaattaaa tcaataaatt tttcatgatc aacaaaggca
     5701 gtagtttcaa tggcagtgtg tatgtgatgt tctttagctg attttaagat ggctttagca
     5761 aattcaaact gagcaaatat ttcacctcct gataaagtta aacctccacc ggattcttcg
     5821 taaaattctt tgtcttttaa tacctctgta ataatttctt ctacagtctt ttcttcaccg
     5881 actaaggtga atttctctcg ttgagcatct ttcatttttt caggtttcat tctttgagat
     5941 tcaggattag aacaccatgg acagcgcaga ggacatcctt ttaaaaaaac agttgtacga
     6001 atacccgggc cgtcatgaat tgaaaagtgt tgaatattaa aaataattcc tttagatatt
     6061 tccataagag ttcctcctct tcataagtct atcctatcac aaaaacgaaa gaaaaacaat
     6121 tacgaacgaa agtttaattt gttgtttttt gctttttatt ttggtagaat aaaacggagg
     6181 tgtaaaatga aaagattgga acaaattatt aaattagtat cagaatatga aaagatcgac
     6241 gttaatacat tatcggaaaa attaaatgta tcgaaagtaa cgattagaaa agatttagat
     6301 aaattagagt caaaaggttt attacacaga gagcatggat atgctgtatt aaatagtgga
     6361 gatgacttaa atgtacgttt gtcaattaac tatgaaatta agagaaaaat tgttcaggaa
     6421 gcagtaaaat tggtgtcaga taatgaaaca ataatgatag aatctggatc gacctgtgct
     6481 ttacttgctg aggaaatttg caagcaaaaa agaaatgtta cgattgtaac aaattcattt
     6541 tttatagcaa attttgtgag agcttatgat tcatgtcgta ttattgttct tggtggagag
     6601 tttcagaagg attcacaggt tactgtggga cctttattaa aagaaatgat acagactttt
     6661 catgtgcatc aagcttttgt tgggacagat ggttacgata aagagatggg ctttacagga
     6721 aaagatttaa tgcgcagtga ggtagttcaa tatatttcag cagcgtcgga taaagtcatt
     6781 gtactaactg actcaagtaa atttgataaa aggggtacag taagaagatt tgctttaagt
     6841 caagtctatg aagtaataac agacgaaaaa ctttctaaac aaaatatagc tacattagaa
     6901 aatgctggga taatggttaa ggtagtttcg taagaggtta aatgtatgaa tcaagatagg
     6961 aataaactgc tctctaaaat tgcttatctg tattatattg aaaacttaaa tcagtcacaa
     7021 atagcagcaa aattaggaat ttatagaacc tctattagta gaatgttaac agaagcaagg
     7081 aatgcaggaa ttgttaaaat tgaaatagag aattttgata ccaatatgtt taagttggaa
     7141 aattatgtaa aagaaaaata tggtctggaa agtttagaaa ttattccaaa tgaatttgat
     7201 gataatccaa caattttatc tgaaagaatt tctcaagttg cagcaggtgt ccttaggaat
     7261 ctaattgatg ataatatgaa aattggcttt tcttggggga aaagtttaag taatttagta
     7321 gatttaattc acagtaaaag tgtccgaaat gttcacttct atcctctagc aggtggtcct
     7381 agtcacatac acgctaaata ccatgtgaat acactgattt atgaaatgtc tagaaaattt
     7441 catggagagt gtacatttat gaatgcaacg attgtgcaag aaaataaatt gttagcagat
     7501 ggtattttgc aatcaagata ttttgaaaat ttgaaaaata gttggaaaga tttagatata
     7561 gctgtagtcg gaattggtga ttttagcaat aaagggaaac atcaatggtt agacatgctt
     7621 acagaggatg actttaaaga attgaccaaa gttaaaactg taggagaaat ttgttgtcga
     7681 ttttttgatt caaaaggtaa agaagtctat gaaaacttac aggaaagaac gatagccatc
     7741 tctttggaag atttaaaaaa tattcctcaa agtttagctg ttgcttacgg tgatacgaaa
     7801 gtatcttcga ttctttctgt cttgcgtgct aatttagtaa atcatttgat tacagataaa
     7861 aatacaattt taaaagtttt ggaagaagat ggtgatttga cttttagaga gattctaggt
     7921 gagtgaaaat gatagactga tcagtttatc gttttttctt tttagtcgat tgcacatttg
     7981 tgcttatata aacaaaaata gtttatctgt tgtttttgga ttgacaactt tattatgtag
     8041 ttgtattcta tagttacaaa agaaaatttt aaaatttcaa atgaaaaaag ctttttacat
     8101 agtgaaatga ggaggaattt atggaaatta ttgttccaga tcaaattatc atgggtttaa
     8161 ttttatatgc tggcgatgcg aaacaacata tttataaagc attagattac ataaaaaatg
     8221 gtacatgtga acggtgtgaa gaagaaatcc agttagctga tgccgcctta ttagaagccc
     8281 ataatctaca aacaaaattc ttggcacaag aagcgtctgg tacaaagaca gaaattacag
     8341 ctctctttgt tcattcacaa gatcatctca tgactagcat gacggagatt aatttaatca
     8401 aagaaattat tagtttgaga aaagaacttc ataaaaaata atactagagt attatcattg
     8461 ttattaacat agaggaggaa aacataatgg tgaagattgg tttgttttgt gcagcaggtt
     8521 tttctactgg tatgcttgta aataatatga aaattgcagc gcaatctagt ggagttgagg
     8581 cagaaataga ggcgttttct cagtctaaat tagcggatta tgcgccaaat atagatgttg
     8641 cactattggg tccacaagtt gcttatacat tagataaatc aaaagaaatt tgtgataagt
     8701 gtgatgttcc gatagctgtt attccgatga tggactatgg tatgttagat gggaaaaaag
     8761 tattagattt ggccctatct ttgattagtg ggtaagaaaa ggagatttat tatgtcaaag
     8821 atggatgttc agaaaatcat tgcaccgatg atgaagtttg tgaatatgcg tggcattata
     8881 gctctaaaag atgggatgtt agcaattttg ccattgacag tagttggcag tttgttcttg
     8941 attatgggac aattgccgtt cgaaggatta aataagagca ttgctagtgt ttttggagct
     9001 aattggacag agccgtttat gcaagtatat tcaggaactt ttgctattat gggtctaatt
     9061 tcttgttttt caattgccta ttcttatgct aagaatagcg gagtagaggc tttaccagct
     9121 ggagttctat ctgtatctgc attctttatt ttgctaagat catcttatat ccctaaacaa
     9181 ggtgaggcga ttggggacgc tattagtaaa gtttggtttg gaggccaagg aattatcggt
     9241 gctatcatta taggtttggt agtaggaagt atttatacct tctttataaa gagaaaaatt
     9301 gttattaaga tgccagaaca agttccacaa gctattgcca aacagtttga agcaatgatt
     9361 ccagcatttg taattttctt atcttctatg attgtatata ttttagcgaa gtcattgact
     9421 aatggcggaa cattcataga aatgatttat tctgctattc aagttccgtt gcaaggttta
     9481 actggatctt tgtatggtgc tattggaatt gcattcttta tatcattttt gtggtggttt
     9541 ggtgttcatg ggcaatcggt agtaaatgga gtagtgacag ctctgctttt atctaatctt
     9601 gatgctaata aagctatgtt agcctctggt aatctatcat tagaaaatgg tgcacatatt
     9661 gttactcaac aatttttaga ttcattttta attctatcag gttcagggat tacgtttggt
     9721 cttgtagttg ccatgctttt tgcagcaaaa tcaaaacaat accaagcctt aggaaaagtt
     9781 gcagcttttc cagcaatatt taacgtaaat gagccagttg tatttggatt tccgattgtc
     9841 atgaatccag ttatgtttgt acctttcatt cttgttcctg tacttgcagc tgtgatagta
     9901 tatggagcta ttgcaacagg tttcatgcaa ccattctcag gggtaacatt gccttggagt
     9961 acaccagcta ttctatcagg atttttggtg ggtggatggc aaggtgttgt gactcagtta
    10021 ttagtattgg cgatgtctac aatggtttac tttccattct ttaagataca agatcgttta
    10081 gcttgccaaa atgaaatcaa acaatcttag aggtatttgt gtgttactgt taaactcaca
    10141 catttgtgct aaaaattaga gagttaaaat ttttctagtt aaaagcttga aaatttctat
    10201 aaaaatcggt attatatttt cgaaagaaat aaaaatattt tcgaaagaaa ggtgcttacg
    10261 atggtaaata cagaagtagc aagaacaaca atcaagacag aatattttgg cagccttact
    10321 gaaaggatga acaaatatcg agaagatgtt ttaaataaaa aaccttatat tgatgctgag
    10381 agagcagttc tagcaacacg cgcctatgaa cgatacaagg aacaacctaa tgtcctaaaa
    10441 cgtgcatata tgctgaaaga aattttggaa aatatgtcta tctatattga agaagaatct
    10501 atgattgcgg gaaatcaagc ttcttccaat aaagatgctc ctatttttcc ggaatatacg
    10561 ctagaatttg ttctcaatga gttggatctt tttgaaaagc gtgatggaga tgttttctat
    10621 attacagaag aaacaaaaga acaacttaga agtattgctc cgttttggga aaataataat
    10681 ttacgtgcta gagctggtgc cttattacct gaagaagtgt ctgtttatat ggaaacagga
    10741 ttcttcggta tggaaggtaa gatgaattct ggagatgctc acttagcagt taactatcag
    10801 aaacttttgc aatttggttt aagaggtttt gaagagcggg ctcgtaaagc gaaggtagct
    10861 ctagatttaa cagatccagc aagtattgat aaatatcatt tttacgactc tatatttatc
    10921 gtaatcgatg ctattaaagt atatgcaaag cgctttgttg ctcttgctaa aagtttagcc
    10981 gaaaatgcaa atcctaaacg taagaaagaa ttacttgaga ttgcagatat ttgctctaga
    11041 gtcccatatg aaccggcaac tacttttgca gaagctattc aatcagtttg gtttattcaa
    11101 tgtattttac aaattgaatc taatggccac tctctttcat atggccgttt tgatcaatat
    11161 atgtatccat atatgaaggc tgatttagaa agtggtaaag aaacagaaga tagcattgtt
    11221 gaacgtctga caaatctttg gattaagaca attacaatta ataaggttcg cagtcaatca
    11281 catacatttt cttcagcagg aagtccttta tatcaaaatg ttacaattgg tggacagact
    11341 cgagataaga aggatgctgt taacccatta tcttatttgg tattaaaatc agttgcacaa
    11401 acccatctac cgcaacctaa tctaactgta cgttaccatg caggtttaga tgctcgtttc
    11461 atgaatgagt gtattgaagt gatgaaactt ggttttggta tgcctgcatt taataatgat
    11521 gagattatta ttccttcttt tattgcaaaa ggagtattgg aagatgatgc ttatgattac
    11581 agtgccattg gatgtgttga aacggcagtt ccagggaaat ggggctatcg ttgcacaggt
    11641 atgagttata tgaacttccc taaggttcta cttatcacga tgaatgatgg aattgatccg
    11701 gcttcgggta aacggtttgc accaagcttt ggtcatttta aggatatgaa gaacttttct
    11761 gaattagaaa atgcttggga taaaacacta agatatttga cacgaatgag tgttattgtt
    11821 gaaaattcta ttgatttatc attggaacga gaagttcctg atattctatg ttcagcattg
    11881 actgatgatt gtattggtcg tggaaaacac cttaaagaag gtggagcagt atatgattat
    11941 atatcaggat tgcaagttgg aattgcaaat ttgtcggatt cattagctgc aattaaaaaa
    12001 ttggtgtttg aggaagaacg tataagccca agtcagcttt ggcatgcact ggaaacagat
    12061 tatgccggag aagaaggtaa ggtcattcaa gaaatgttga ttcatgatgc acctaagtat
    12121 ggtaatgatg atgattatgc tgacaaattg gttactgctg cttatgacat ttatgttgat
    12181 gaaattgcta aatatcctaa tacacgttat ggaagaggtc caattggagg aattcgttat
    12241 tcaggaacat cttctatctc agccaacgta gggcagggac gtggaacatt agcaactcca
    12301 gatggacgca acgcgggtac accgttagca gagggttgtt caccatcaca taatatggat
    12361 caacacggcc ctacatctgt tttaaaatct gtttcaaaat taccaacaga tgaaatcgta
    12421 ggtggggttc tcttaaatca gaaagtaaat cctcaaacgt tagccaaaga agaagataaa
    12481 ttaaaactaa ttgctttgtt acgaacattc tttaatcgtt tacatgggta ccatattcaa
    12541 tacaatgttg tttccagaga gacgctgatt gacgctcaga aacatcctga aaaacacaga
    12601 gacttaattg ttcgtgttgc aggatactct gcattcttca atgttctttc taaggcaacc
    12661 caagatgaca ttataggacg tactgagcat actttgtaaa ataaagaggt tctttttatg
    12721 gaatttatgc ttgacacatt aaatttagat gagattaaaa agtggtctga aattttgccg
    12781 ctagctgggg taacttcaaa tcccactatt gcaaaaagag agggttctat taattttttt
    12841 gaacgaatca aagatgtaag agaattgatt ggctctacac cctctattca tgttcaggtg
    12901 atttctcaag attttgaagg catcttaaag gatgctcata aaattcgaag acaagcagga
    12961 gatgatatat ttatcaaagt acctgttact ccagctggat tacgtgcaat aaaggcgcta
    13021 aaaaaagagg gctaccatat cactgcaaca gctatttata cagttattca gggattatta
    13081 gctatcgaag caggagcgga ttacctagct ccatattata atagaatgga aaatctgaac
    13141 attgattcaa attctgtcat tcgtcaatta gctcttgcta ttgatagaca gaactctcct
    13201 agtaagattt tagctgcatc ctttaaaaat gtagcacaag taaataatgc tttagctgca
    13261 ggtgcgcatg ctgttacagc aggagcggat gtttttgaat cagctttcgc catgccatct
    13321 atccaaaagg cggttgatga tttttctgac gattggtttg ttattcaaaa tagtcgttcc
    13381 atttagatag agaggaaata catatgagaa tttttgctag tccttctaga tatattcagg
    13441 gggaaaatgc cttgtttgaa aatgccaaat caattttgga tttgggaaat tgccctattc
    13501 tattatgcga tcagttggtt tatgatattg ttggaaaacg atttgaagat tacctacata
    13561 ggtatggttt ccatattgtt ctggcgctat ttaatggtga agcttctgac aatgaaatca
    13621 atcgagttgt tgccttggct gagaaagaaa attgtgatag tattatcggt cttggtgggg
    13681 gaaagacgat tgatagcgca aaagctattg cagatttgat tgaaaagcct gttattattg
    13741 ctccaacaat tgcatcgacc gacgcacctg tatctgcttt atctgttatt tatacagatg
    13801 aaggtgcatt tgatcattat ctattttatt ctaaaaatcc agatttagtt ttggttgata
    13861 caaaagttat ttcacaagcc cctaagcgtt tattagcgtc tggtattgca gatggtttag
    13921 caacttgggt tgaggcgcgt gcggttatgc aggcaaatgg aaaaactatg ttgggacaac
    13981 agcaaacatt ggctggagtt gcaattgcga agaaatgtga agaaacgctg tttgcagatg
    14041 gtttacaggc tatggcagct tgtgaagcta aagtggtgac accagcatta gaaaatattg
    14101 ttgaagctaa tactttattg agtggtctag gttttgaaag tggaggatta gctgcggcgc
    14161 atgcaattca taatggtttt actgcattga caggtgacat tcatcattta acacatggtg
    14221 aaaaagtagc ttatggaact ttagtacaac tattattgga aaatagacct aaagaagaac
    14281 ttgataagta tattgagttt tacaaaaaaa ttggtatgcc aacaactcta aaagaaatgc
    14341 atttggatca agttggatat gatgatttaa taaaagttgg taaacaagca actatggagg
    14401 gtgagacaat tcatcagatg ccgtttaaga tttcgccttc agatgttgct caagctatta
    14461 tcgctgtaga tgcctatgta aattcaaaat aaacaataag gactactgtt ttccaaatgg
    14521 tagtctttta ttgatccctg tattgaattc tatagaagat tgaaatagga tgagaacaaa
    14581 tcgattggga aagtaaaatt aatttctata aatgttttag caattgtttc gtactatttc
    14641 agattcagtc tactatatgt tcttcataaa tcaaaaagcg acataggttg tcggctattt
    14701 attgtgaata cattaattag cattccagtt ttatcttcgg tctaaaataa gtattttgtg
    14761 ctatacgaga taagcttctt gacttactcc ttgatttact gcataacaat gggataaaaa
    14821 gtgggagata gagcaattca tagtcatcaa aattaatgag atacagtata cagtttttcc
    14881 tttaaacaca tttcaaattc cctcaaaaat ggtataatag taacatcaca aaattggaga
    14941 gagaccatga gtttttacaa tcataaagaa attgagccta agtggcaggg ctactgggca
    15001 gaacatcata catttaagac aggaacagat gcatcaaaac ctaagtttta tgcgcttgat
    15061 atgttccctt atccgtctgg agctggtctg cacgtaggac acccagaagg ttatactgca
    15121 accgatatcc tcagtcgtta caaacgtgcg caaggctaca atgtccttca cccaatgggt
    15181 tgggatgctt ttggtttgcc tgcagagcaa tacgctatgg atactggtaa tgacccagca
    15241 gaatttacag cggaaaacat tgccaacttc aaacgtcaaa ttaatgcgct tggattttct
    15301 tatgactggg atcgtgaagt caacacaaca gatccaaact actacaagtg gactcaatgg
    15361 attttcacca agctttacga aaaaggcttg gcctatgaag ctgaagtgcc agtaaactgg
    15421 gttgaggaat tgggaactgc cattgccaat gaagaagtgc ttcctgacgg aacttctgag
    15481 cgtggaggct atccagttgt ccgcaaacca atgcgccaat ggatgctcaa aatcacggct
    15541 tacgcagagc gcttgctcaa tgacttagat gaactagatt ggtcagagtc tatcaaggat
    15601 atgcaacgca actggattgg taaatcaact ggtgccaatg taactttcaa agtaaaagga
    15661 acagacaagg aatttacagt ctttactact cgtccggaca cacttttcgg tgcgactttc
    15721 actgtcttgg ctcctgaaca tgaattagta gacgctatca caagttcaga gcaagcagaa
    15781 gctgtagcag actataaaca ccaagccagc cttaagtctg acttggctcg tacagacctt
    15841 gctaaagaaa aaacaggggt ttggactggt gcttatgcca tcaaccctgt caatggtaag
    15901 gaaatgccaa tctggattgc agactatgtc cttgctagtt atggaacagg tgcggttatg
    15961 gctgtgcctg cccacgacca acgtgactgg gaatttgcca aacaatttga ccttccaatc
    16021 gtcgaagtac ttgaaggtgg aaatgtcgaa gaagctgcct acacagagga tggcctgcat
    16081 gtcaattcag acttcctaga tggactcaac aaagaagacg ctattgccaa gattgtggct
    16141 tggttggaag aaaaaggctg tggtcaggag aaggttacct accgtctccg cgactggctc
    16201 tttagccgtc aacgttactg gggtgagcca attccaatca ttcattggga agatggaact
    16261 tcaacagctg ttcctgaaac tgaattgccg cttgtcttgc ctgtaaccaa ggatatccgt
    16321 ccttcaggta ctggtgaaag tccactagct aacttgacag attggcttga agtgactcgt
    16381 gaagatggtg tcaaaggtcg tcgtgaaacc aacactatgc cacaatgggc tggttcaagc
    16441 tggtactacc tccgctatat tgatccacac aatactgaga agttggctga tgaggacctc
    16501 ctcaaacaat ggttgccagt agatatctac gtgggtggtg cagagcatgc tgttcttcac
    16561 ttgctttacg ctcgtttctg gcacaaattc ctctatgacc tcggtgttgt tccgactaag
    16621 gaaccattcc aaaaactctt taaccaaggg atgattttgg gaacaagcta ccgtgaccac
    16681 cgtggtgctc ttgtggcaac cgacaaggtt gaaaaacgtg atggttcctt cttccatgta
    16741 gaaacagggg aagagttgga gcaagcgcca gccaagatgt ctaaatcgct caagaacgtt
    16801 gttaacccag acgatgtggt ggaacaatac ggtgccgata cccttcgtgt ttatgaaatg
    16861 tttatgggac cactcgatgc ttcgattgct tggtcagaag aaggtttgga aggaagccgt
    16921 aagttccttg accgagttta ccgtttgatt acaagtaaag aaatccttgc ggaaaacaat
    16981 ggtgctcttg acaaggttta caacgaaaca gtcaaagctg ttactgagca aattgagtct
    17041 ctcaaattca acacagctat tgcccaactt atggtctttg tcaatgctgc taacaaggaa
    17101 gataagcttt atgttgacta tgccaaaggc tttattcaat tgattgcacc atttgcacct
    17161 cacttggcag aagaactctg gcaaacagtc gcagaaacag gtgagtcaat ctcttatgta
    17221 gcttggccaa cttgggacga aagtaaactg gttgaagacg aaatcgaaat cgttgtccaa
    17281 atcaaaggta aagtccgtgc caaactcatg gtcgctaaag acctatcacg tgaagaattg
    17341 caagaaattg ctctagcgga tgaaaaagtc aaagcagaaa ttgacggtaa ggaaatcgtg
    17401 aaagtgatta gtgtaccaaa taaattggtt aatattgttg taaaataacc aatttatttg
    17461 ctgatttcca acctcaaaca gtttcccaaa ctgtttgagc caactaaact cgttaatatc
    17521 gttgtgaaat aaggtaggaa tccttcagag tagaatctgg aggatttttt gaatcttctt
    17581 atgaaagtat ggtatactat gggcaactat aaagtttgaa aagtgaaaaa aggagaaagc
    17641 tatgccagta aatgaatatg gtcaaatgat tggggagtca atggaaggtt atacaccagg
    17701 tgaactgcct tctattgatt tcttagaagg gcgttatgct aggatagagg ctctttcagt
    17761 ggaaaagcat gcggaggatt tgctagctgt ttatgggcct gatacgcctc aggagatgtg
    17821 gacctacctt tttcaggagc cagtagcaga tatgggggag ctggttagcc ttttacatca
    17881 gatgttggct cgtaaggacc gtttttacta tgcaatcata gacaaggcga ctggtaaggc
    17941 tttgggatct ttttctctca tgcgcattga ccagaataac cgagtaatag aagtcggagc
    18001 agtcactttt tctccagagc taaggggtac acggatagga actgaagctc agtatctcct
    18061 agctcgctat gtttttgagg agctaaacta tcgtcgctac gagtggaaat gcgatgcctt
    18121 aaatctgcca tccagacgag ctgcggagcg tttgagcttt atttatgaag gaaccttccg
    18181 tcaggcagtg gtttataagg gacgtacgag agatacggat tggttgtcta tgattgataa
    18241 ggactggcct caagtcaaag atcgtttgga aacatggttg cgtcctgaaa attttgataa
    18301 aaatggacag cagtacaaga gcttgagaga actttaagag gtgttgacat gattactatt
    18361 aaaaagcaag aaattgtcaa gctagaggat gttttacatc tctatcaggc tgtcggttgg
    18421 acaaattata cccatcaacc agagatgctg gagcaggcct tatctcattc attagtaatt
    18481 tatctggcac ttgatggtga tgctgtggtg ggcttgattc gtttggttgg agatggattc
    18541 tcatcagtat tggttcagga tttaatcgtt ttaccaatct atcagcgtca aggaattggt
    18601 agtgccttga tgaaagaggc tttagaggat tacaaagatg cctatcaagt ccagctggtg
    18661 acagaagaga cagaaagaac cttgggcttc tatcgttcta tgggctttga aatcttatcc
    18721 acctataatt gtatagggat gacttggatg aatcgtaaaa aataacaaaa cttgtttttt
    18781 cttaagcaaa atttaaggat ggtctagtat tatatagtca ttaaataaag acctcctaac
    18841 tttatttaat aaaatcctaa acttttttca tcacaatctc ctaatgaagc cacccaatca
    18901 ggtggctttt ttgcgtggtg aggtgctggt gatagaaatt ttttgcaaaa tagtaaaatt
    18961 ttagaaaagt taagctagtt ttaagtttcg tcttgtatca tgtagttatt aaataaagac
    19021 ctcctaactt tatttaataa aatcctaaac ttttcttttt cataataatc tcccttaact
    19081 ccacccaatc aggtggagtt ttttagctct atttcaggct tttggggact attctaaaaa
    19141 taatttttcg atatttttcg gtatttttcg gattttggtc ggggaattgg cggggacttt
    19201 tttagcgaat ataactaaga aataggtctg tggtcgcttc agctagttca aactcaattt
    19261 gattgtaagt gactgttaat tgaagaactg gaactactgt aataatgatt ttgcttgtct
    19321 agtagtggcg tattaaatga gaagtgacat gtaagattgt ctcttcgttt acgaaatcaa
    19381 aatttctatg aaattgatag aatccctaac gttctcttaa tcttaaccgt cttgtcgtac
    19441 agcggttgaa gaaaatgtaa acctttgaca aaattcgtga actatgagat aataaaaagg
    19501 aattgagtac tagttctata tcataggcta gaaaagaccc caagctcacg accaaataag
    19561 cttggggtct tttttgacac tatttgtcct tgtttagcca tttatcgact atacgaagaa
    19621 cgacaccgac cacaattggt ccgatgatag ttttgagtac taattccatc atgggctatc
    19681 tcacctcctt tcgtaggcgg tgtagcagtg tcgtagaata ttataccaca taagtgctaa
    19741 acttaggagt cacccaatca ggtggctttt ttgtttgtgg cttggttttt tgatataata
    19801 gagccatgag tagaatttta gataatgaga taatggggga tgaggagtta gtagaacgca
    19861 cgctccgtcc tcagtattta cgtgaatata tcggacagga taaggtcaag gaccagctac
    19921 aaatctttat tgaagctgcc aaaatgcggg atgaagcgct ggatcatgtg ctcttatttg
    19981 ggcctccagg tctcgggaaa acgaccatgg cctttgttat tgccaacgaa ctgggagtca
    20041 atcttaagca gacgtcgggt ccagtcattg aaaaagccgg agatctggta gctattttga
    20101 atgagttaga gcctggggat gtacttttta ttgatgagat ccatcgtttg ccaatgtcag
    20161 tggaagaggt gctttatagt gctatggagg acttctacat agatattatg attggggctg
    20221 gtgagggtag tcgtagtgtt catttggagt taccaccttt taccttgatt ggtgcgacga
    20281 ctcgggctgg tatgctctcc aatccgctac gggcacgttt tgggattaca ggccatatgg
    20341 agtattatgc ccatgctgac ttgacagaaa ttgtcgagcg gacggcagat atttttgaga
    20401 tggaaatcac tcatgaggca gcatctgagt tggccctacg tagtcgtggg acccctcgta
    20461 ttgccaatcg tctcctcaag cgcgtgcgcg attttgccca gataatgggg aatggggtaa
    20521 ttgatgatat tattaccgat aaggctttga ctatgctgga tgttgaccat gaaggtttgg
    20581 actatgtgga tcaaaaaatc cttcgtacca tgattgagat gtacagtgga ggacctgttg
    20641 gtctaggaac tctttctgtg aatatcgccg aagagcgtga gacagttgaa gatatgtatg
    20701 agccttactt gattcaaaaa ggttttatca tgcggacacg gtctggacgg gtggcgactg
    20761 ctaaggcata tgagcactta ggttatgaat acagtgaaaa ataagcaaga aatcttagag
    20821 gcttttagag aaaatccaga tatgatggcc attctgacga tcatccgaga ccttggtctg
    20881 aaagactcgt ggttggcagc aggttctgtc agaaatttca tttggaatct tttgtcagac
    20941 aaatcccctt ttgatcatga aacagatata gatgtgattt tctttgatcc agatttttct
    21001 tatgaggaaa ccttattact ggagaaaaag ctgcgagagg attttcctca gtaccagtgg
    21061 gaattgaaaa atcaggtcta tatgcatcag cacagtcctc acactgcttc ctataccagt
    21121 tctcgtgatg ctatgagtaa gtatccagaa cggtgtacga cagttggact gcgcttgaat
    21181 gaagaatcag attttgaact ctatgcacct tatggtttgg aggatatttt gaattttcaa
    21241 gttcgtccaa ctcctcattt cttagaaaat gaagaccgaa tggaactcta tcaaacacgt
    21301 ttatccaaga aaaattggca ggagaaatgg aaaaatttga tttttaaaaa tacttaagga
    21361 aactttaagc tagggagtgt acactaagtt cataagttaa gaagacctta acttaaactc
    21421 ctaaaacttt ttcataataa tctccctata aaaataaagt cgcccaatca ggcggcttat
    21481 ttttttgaaa aatgggcttg gtgcctgaga ataaatagct tagtgataga agaaaatggg
    21541 gaaatatggt ataataaaac gatagatttt tgaataggaa taagatcatg tttggatttt
    21601 ttaagaaaga taaggctgtg gaagtagagg ttccgacaca ggttcctgct catatcggca
    21661 tcatcatgga tggcaatggc cgttgggcta aaaaacgtat gcaaccgcga gtttttggac
    21721 ataaggcggg catggaagca ttgcaaaccg tgaccaaggc agccaacaaa ctgggcgtca
    21781 aggttattac ggtctatgct ttttctacgg aaaactggac ccgtccagat caggaagtca
    21841 agtttatcat gaacttgcca gtagagtttt atgataatta tgtcccggaa ctacatgcga
    21901 ataatgttaa gattcaaatg attggggaga cagaccgcct gcctaagcaa acctttgaag
    21961 ctttaaccaa ggctgaggaa ttgactaaga acaacacagg attgattctt aattttgctc
    22021 ttaactatgg tggacgtgct gagattacac aggcgcttaa gttgatttcc caggatgttt
    22081 tagatgccaa aatcaatcca ggtgacatca cagaggaatt gattggtaac tatctcttta
    22141 cccagcattt gcctaaggac ttacgagacc cagacttgat tatccgtact agtggagaat
    22201 tgcgtttgag caatttcctt ccatggcagg gagcctatag tgagctttat tttacggaca
    22261 ccttatggcc tgattttgac gaagcggcct tgcaggaagc tattcttgcc tataatcgtc
    22321 gtcatcgccg atttggagga gtttaggagg aaatatgacc caggatttac agaaaagaac
    22381 cttgtttgca gggattgccc tggctatttt cctaccaatt ttaatgattg ggggcctctt
    22441 gcttcagata gcaatcggaa tcatagccat gctagccatg catgaacttt tgaagatgag
    22501 aggtctagag accatgacga tggagggcct cttgaccctc tttgcaacct ttgcattgac
    22561 cattcccttg gagaattacc tgactttttt gccagttgat gggaatgtgg ttgcctatag
    22621 tgttttgatt tcaatcatgt taggaacgac cgtttttagc aagtcttata cgattgagga
    22681 tgcggttttc cctcttgcta tgagcttcta cgtgggcttt ggatttaatg ctttactaga
    22741 tgctcgtgtt gcaggtttgg acaaggctct cttagccttg tgtatcgtct gggcgacaga
    22801 cagtggtgcc tatcttgttg ggatgaacta tgggaaacga aagttagcac caagggtatc
    22861 gcctaataaa acccttgagg gtgccttggg tggtatttta ggagcaattt tagtaaccat
    22921 tatctttatg atagttgaca gtacagttgc tcttccatat ggaatttaca agatgtcagt
    22981 ctttgctatt ttctttagca ttgctggaca atttggtgat ttactagaaa gttcgatcaa
    23041 acgtcatttt ggtgttaagg attctgggaa atttatccct ggacatggtg gtgttttgga
    23101 tcgtttcgat agtatgttgc ttgtatttcc aatcatgcac ttatttggac tcttttaatc
    23161 aaaagacgga ggaaacgcta tgctcggaat tttaaccttt attctggttt tcgggattat
    23221 tgtagtggtg cacgagttcg ggcacttcta ctttgccaag aaatcaggga ttttagtacg
    23281 tgaatttgcc atcggtatgg gacctaaaat ttttgctcac attggcaagg atggaacggc
    23341 ctataccatt cgaatcttgc ctctgggtgg ctatgtccgc atggccggtt ggggtgatga
    23401 tacaactgaa atcaagacag gaacgcctgt tagtttgaca cttgctgatg atggtaaggt
    23461 taaacgcatc aatctctcag gtaaaaaatt ggatcaaaca gccctcccta tgcaggtgac
    23521 ccagtttgat tttgaagaca agctctttat caaaggattg gttctggaag aagaaaaaac
    23581 atttgcagtg gatcacgatg caacggttgt ggaagcagat ggtactgagg ttcggattgc
    23641 acctttagat gttcaatatc aaaatgcgac tatctggggc aaactgatta ccaattttgc
    23701 aggtcctatg aacaatttta tcttaggtgt cgttgttttt tgggttttaa tctttatgca
    23761 gggtggtgtc agagatgttg ataccaatca gttccatatc atgccccaag gtgccttggc
    23821 caaggtagga gtaccagaaa cggcacaaat taccaagatt ggctcacatg aggttagcaa
    23881 ctgggaaagc ttgatccaag ctgtggaaac agaaaccaaa gataagacgg caccgacttt
    23941 ggatgtgact atttctgaaa aggggagtga caaacaagtc actgttacac ccaaagatag
    24001 tcaaggtcgt taccttctag gtgttcaacc gggggttaag tcagattttc tatccatgtt
    24061 tgtaggtggt tttacaactg ctgctgactc agctctccga attctctcag ctctgaaaaa
    24121 tctgattttc caaccagatt tgaacaagtt gggtggacct gttgctatct ttaaggcaag
    24181 tagtgatgct gctaaaaatg gaattgaaaa tatcttgtac ttcttggcaa tgatttccat
    24241 caatattggg atttttaatc ttattccgat tccagccttg gatggtggta agattgtgct
    24301 caatatccta gaagccatcc gccgcaaacc attgaaacaa gaaattgaaa cctatgtcac
    24361 cttggccgga gtggtcatca tggttgtctt gatgattgct gtgacttgga atgacattat
    24421 gcgactcttt tttagataat cgaggaatat tatgaaacaa agtaaaatgc ctatcccaac
    24481 gcttcgcgaa atgccaagcg atgctcaagt tatcagccat gctcttatgt tgcgtgctgg
    24541 ttatgttcgc caagtttcag caggtgttta ttcttatcta ccacttgcca atcgtgtgat
    24601 tgaaaaagct aaaaacatca tgcgccaaga attcgaaaag attggtgctg ttgagatgtt
    24661 ggctccagcc cttcttagtg cagaattgtg gcgtgaatca ggtcgttacg aaacctatgg
    24721 tgaagacctt tacaaactaa aaaaccgtga aaaatcagac tttatcttag gtccaactca
    24781 cgaagaaacc tttacagcta ttgtccgtga ttctgttaaa tcttacaagc aattgccact
    24841 caacctttat caaattcagc ccaagtatcg tgatgaaaaa cgcccacgta atggacttct
    24901 tcgtacacgt gagtttatca tgaaggatgc ttatagtttc cacgctaact atgatagttt
    24961 ggatagtgtt tatgatgagt acaaagcagc ctatgagcgt atttttactc gtagtggttt
    25021 agacttcaag gctattattg gtgacggtgg agccatgggt ggtaaggata gccaagaatt
    25081 tatggccatt acatctgctc gtacagacct tgaccgctgg gttgtcttgg acaagtcagt
    25141 tgcctcattt gacgaaattc ctgcagaagt gcaagaagaa atcaaggcag aattgctcaa
    25201 atggatagtc tctggtgaag ataccattgc ttactcaagt gagtctagct atgcagctaa
    25261 cttagaaatg gcaacaaacg agtacaaacc aagcaaccgt gttgtcgctg aagaagaagt
    25321 tactcgtgtt gcaacgccag atgttaaatc aatagatgaa gttgcagctt tcctcaatgt
    25381 tccagaagaa caaacgatta aaaccctctt ctacattgca gatggtgagc ttgttgcagc
    25441 ccttctagtt ggaaatgacc aactcaacga agtcaagttg aaaaaccact taggagcaga
    25501 tttctttgac gttgctagcg aagaagaagt ggcgaatgtt gttcaagcag gatttggttc
    25561 acttggacca gttggtttgc cagagaatat taaaattatt gcagatcgta aggtgcaaga
    25621 tgttcgcaat gcagttgtcg gtgctaacga agatggctac cacttgactg gtgtgaaccc
    25681 aggccgtgat tttacttcag aatatgtgga tatccgtgaa gttcgtgagg gtgaaatttc
    25741 cccagatgga caaggtgtcc ttaattttgc gcgtggtatt gagatcggtc atattttcaa
    25801 actcggaact cgctattcag caagcatggg agcagatgtc ttggatgaaa atggtcgtgc
    25861 tgtgccaatc atcatgggat gttacggtat cggtgtcagc cgtcttcttt cagcagtgat
    25921 ggagcaacac gctcgcctct ttgttaacaa aacgccaaaa ggtgaatacc gttacgcttg
    25981 gggaatcaat ttccctaaag aattggcacc atttgatgtg catttgatta ctgttaatgt
    26041 caaggatgaa gaagcgcaag ccttgacaga aaaacttgaa gcaagcttga tgggagctgg
    26101 ttatgaagtc ttgacagatg accgtaacga acgtgtcggt gttaaattta gcgatagtga
    26161 cttgattggt cttccaatcc gtatcactgt tggtaaaaaa gcggccgatg gcattgtaga
    26221 agttaagatc aaggcaactg gtgacaccat tgaggttcat gcagataacg tgcttgaaac
    26281 gcttgaaatc ctaagtaaga aataaaaact ataatcagaa gaaaaacaag gaaaaaatgt
    26341 aactagtttt taccttgttt tttctgtata atgggagaaa tgagtagata aagaggtaaa
    26401 tgtatgctaa gatttccaaa ggattttgtc tggggatcct ctacttctgg accgcagaca
    26461 gaaggacgtg tagctggtga cggtaaggga gacaatctct gggattactg gttccaagtg
    26521 gagccaaatc gttactataa tgggattggt tcagataaga catcgacttt ttatgaaaat
    26581 tgggagcggg atattgagct tttgttagag actggtcaca cagcctttcg gacttctatt
    26641 cagtggtcac ggatttttcc acaaggctgt ggaaaagtca accctcaagg tgtggatttt
    26701 tatcgtaagg tctttgaggc tattaaggct aaaggaattc gtctgttagt caatctctat
    26761 cattttgatt taccttttgc ccttcaagag gatggtgatg gttgggaaaa taaggcgaca
    26821 gtttcagcct atgaagacta tgctcgtttt tgttttgaga cttatggaga tttagtggat
    26881 caatggatta cctttaacga gcccatcgtt cctgtagaat ttggttattt ttatgatgcc
    26941 cattatccac ataaggtgga tgcagaggca gctgttaagg tagcctatca tacacaattg
    27001 gccagcagcc gggctgttaa ggcttgccat gaacttttgc ctgattccaa gattgggatt
    27061 gtcctcaact tgacaccggc ttatccacgt agccagcatc ctgctgatgt caaggcagct
    27121 cgtattgcgg ccctttttca ggcccaatct ttcttagatc catctgtctt ggggacttat
    27181 ccacaggagt tggtagaaat cttgcatgaa cacggtcttt tacctgatgc tacagaggaa
    27241 gagttggaac tcattcgtga taatacggtg gacttccttg gtgtgaacta ctatcaacct
    27301 ttgcgtgtta tggctcctcg atttgctaag catccagaga gtccactctt accagaacat
    27361 ttttacgagc attatgtgat gcctggacgt aaaatcaatt ctcaccgtgg ttgggagatt
    27421 tatgagcaag ggatttatga catcgcccaa aatatcaagg aaaattatgg caatattgag
    27481 tggatgttga ctgagaatgg tatgggtgtt gaaggggaag aaaaattccg tcaagatgga
    27541 atgattcaag atgattaccg tattgacttt gtaaaaggtc atcttcgtga acttcaccgt
    27601 gccattgaag atggtgccaa ctgtaagggc tacttgattt ggacctttat tgactgctgg
    27661 tcatggctca acagctataa aaatcgctat ggtttggtcg aattagactt ggaaacgcaa
    27721 gaacgtcgtc tgaagaaatc aggccactgg ttcaaagaat taagcgataa taatggattt
    27781 taaaaaggac tctgactgat tatcccaatc ggtcagagtt tttatgctta caggagctta
    27841 atttgaacta taccaatttt tactcttgac aagtgaaaga aacaagtata tactgttttt
    27901 actgattcta taaaagatga attagactat accaatttta aggagaaagc acagcttgcc
    27961 tgtgtcgtat atactatgtg tggaattgtt ggtgttgttg gaaacacaaa tgcaactgat
    28021 attttgattc aagggcttga aaagcttgaa taccgtggct atgattctgc gggaattttt
    28081 gtcctagatg gtgctgataa ccatttggtg aaggcggttg gtcgtattgc agaattgtct
    28141 gccaagacag ctggtgttga gggaacaact ggtatcggac atactcgttg ggctactcac
    28201 ggaaaaccaa ctgaggacaa tgctcaccca caccgctctg agacagaacg ttttgtcttg
    28261 gtgcataatg gggtgattga gaactatctt gaaatcaagg aagaatacct tgcaggtcac
    28321 cacttcaagg ggcagacaga tactgaaata gccgttcatt tgattggaaa atttgcggaa
    28381 gaagaagggc tctcagttct tgaagccttc aaaaaagctc ttcatattat ccgtggttca
    28441 tatgcctttg ccttgattga ctctgaaaat ccagatgtca tctatgtagc gaaaaacaaa
    28501 tctccacttt tgattggtct tggggaaggc tacaatatgg tctgctcaga tgctatggct
    28561 atgattcgtg aaaccaacca atacatggaa attcatgacc aagagttggt aatcgtcaag
    28621 gctgatagcg tggaagttca agactatgat ggtaacagtc gtgaacgtgc tagctatact
    28681 gcggaacttg acttgtcaga tatcggtaag ggaacttatc cttactacat gcttaaggaa
    28741 attgatgagc aaccaactgt tatgcgtaaa ctcattcaag cctacacgga tgatgctggt
    28801 caagtagtga ttgatcctgc tatcattaag gctgttcaag acgcagaccg catctacatc
    28861 cttgcagctg gaacatctta ccatgcagga tttgcttcta agaaaatgtt ggaagaattg
    28921 acagatacac cagttgaact tggaatctca tctgagtggg gctacggtat gccacttctc
    28981 agcaagaaac cactcttcat ctttatcagc caatctggtg aaacagcgga tagtcgtcaa
    29041 gttttggtca aggctaatga aatgggaatt ccaagcttaa cagtgacaaa cgttccaggt
    29101 tcaaccctct cacgtgaagc caactatacc atgctccttc acgcaggtcc tgaaattgcc
    29161 gtggcatcaa ctaaagccta tacagcgcaa atcgcagccc ttgccttcct tgcaaaagca
    29221 gtcggagaag caaatggtaa tgctaaagcg caagcctttg acctggttca tgaattgtca
    29281 atcgtagctc agtctatcga atcaactctt tcagagaaag aaaccattga agccaaggtt
    29341 cgtgaacttc ttgaaacaac tcgtaacgcc ttttacatcg gacgtggtca agattactac
    29401 gtagccatgg aagcaagtct caaactcaaa gagatttctt atatccagtg tgaaggtttt
    29461 gcggcaggag aactcaagca cggaaccatt gccttgattg aagaaggaac gcctgtcttg
    29521 tctctcttgt cagatccagt tcttgccaac catactcgtg gaaatatcca agaggtcgca
    29581 gcccgtggtg ccaaagtcct cactatcgca gaagagaatg tagccaaaga taccgacgat
    29641 atcgtcctta cgaccgtaca tccatacctc tcaccaattt caatggtcgt accaacgcaa
    29701 ttagtcgctt actttgcaac cctccaccgt ggcttcgatg tggacaaacc acgtaacctt
    29761 gccaagtcag taacggtaga ataagctaaa aaagtctagt tatctaggcc tttttcttgt
    29821 gagcaaattg gttgcttgta ctcaagattc gtgttatact cttcgaaaat ctcttcaaac
    29881 cacgtcaacg tcgccttgcc gtaggtatgg ttactgactt cgtcagttct atccacaacc
    29941 tcaaaacact gttttgagca gcctgcagct agcttcctag tttgctcttt gattttcatt
    30001 gagtattaga ataatttttc aaattgaagt acagagatag ataaggagaa tcacaatggt
    30061 agaattggga atttcaacat ttggggaaat aacggagctt gaagggactg gacaaactta
    30121 cagtcatgct gaacgcattc gccagttggt ggcagagatt gagctggctg acaaggttgg
    30181 tttggatgta tatgggattg gtgagcacca tcgggcggat tttgcagtat cagccccaga
    30241 gattgttctg gccgctgggg cagtcaatac caagaaaatc cgtttgacca gtgcagtcag
    30301 cattctgtca agcatggacc cgattcgttt gttccaacag tatgccacta tcgatgcttt
    30361 gtcaaatgga cgagcggaga ttatggctgg aaggggctct ttcacggaat ctttccctct
    30421 gtttggttat gacttgaaag actacgactc tctttttgat gagaaattag ccttgcttca
    30481 gttagtcaat gaaaagacca agttagactg gcaaggtcga ttgactcaaa cgattgctgg
    30541 taaagaagtt tatcctcgtc cagttcagga caaattgccc ttgtggatag ctacaggtgg
    30601 tcatgtcgaa tcaacagtga agattgctca ggctggtcta ccgattgtat atgctattat
    30661 tggtggtaat ccacgttatt ttaaaaagtt gattcaggct tatcgtgaga ttggaagcga
    30721 agcgggtcat gctgacaaag acttgaaagt gggagcccat tcttgggggt ggattgcgga
    30781 agatggtgag caggcggtga aagattattt ccatccgact aagcaagtgg tggatgctat
    30841 ttccaaagac cgtccgcact ggcaggaatt gcgttatgag caatatttgg agcaggtagg
    30901 gccaaatggc gccatgtttg ttggcaatcc agatcaggtg gccgaaaaat tgattcgcat
    30961 gatagaggat ttaggattgg accgcttcat gcttcatcta ccgcttggtt ctatgcctca
    31021 tgaccaggtt ctgagagcta ttgaactctt cggaacacaa gttgcaccca aagtacgagc
    31081 ttattttgct atgaaagagg cttaataaaa aatcctaatc aagtttatta ggacaacaaa
    31141 tattgtacga aaattaatcc cccgagctat aatgcttggg ggatttttct ataggagggc
    31201 tagtttagtt ctctttttta ttttttagta agaaaccgag accaaggagc gcaaggaggc
    31261 tgattcctgc aaataggagt ttgttttcgt ttttgattcc tgtatttgga agttcagctt
    31321 gtctatctgg ggttgcaggt atatttttct tgctagagtt ttctaccgat tcgttttgaa
    31381 ccgcttcttt tacagatgat gcttgtgctt cttgtgctgg ttgttcagct tgtgaatcag
    31441 ctgtagcttg gctaggttta ttttccgcat cagctacttt ggcatctggt ttagtagaat
    31501 caggtctagc ttctggagct gggtcttgat gttcaggctt ggaaggggtt gagtctggtt
    31561 tctcttctgc agttgactca tggctagttc cattttgaga gactcgaaga acagtagctg
    31621 taagggcatt caatttcaag cctttttcag tccattcaag tcctttcggg ttggcaattc
    31681 cgactggtcc tgcttggttt tcatctgcca aaacttccgc atttcttaga tgtgcaaagg
    31741 cagttcccaa attaaattcg cgagcttttt catccgcatt gacaaagact gcgtagatat
    31801 cgccgtttgg agcagtgatt tggtagccaa tcactacatc ctctttttcc acaccatttt
    31861 ggcctgggac agtgatgagg tggacacggt ctttgatatc ttggagactc ttaagtcgga
    31921 aggcatctgt agattgacga agggcaatca aacctttcat atagtcacgg ctcttgacat
    31981 tttcaggata agctttacca tctgtagcct tagtccagtc aaacttgttg actgcgtcgc
    32041 tagaatcgta agaatcatgg atgaagtaag gatagtcaaa tgggttgccg tccttatcac
    32101 gcaacaagtg agatttgttt ggaaccttat cctctgctac tggagtcttg taggctgggt
    32161 cacggaattg tttagtacgt ccatattcct gaccggagtg gataaatgga gttccttgag
    32221 ctgtcaagac catgagattt ccaagtcgta aacgacggtg gatttcagca tagttctcag
    32281 ccttgcttgg gtcttttttg atagactggg caatgatgtc aaagagggtc aagttatcat
    32341 gggctgcgat gtattggatg acatctccag ggctgtcagc ttcaaagtta gttggttgag
    32401 caatgagatt tttaaagatg gtgttgacat cacgcttgcc acctgtgata aaggcaggtt
    32461 gaccttcgtt tggataacca gatttgaggt tgttacggat gtcatctgaa aagacagcga
    32521 cagtatcggt atgtttcatc caatcttggt cagcagcttt agtaggcatg ttttcatcac
    32581 cggcataggt tctccaacct tcgcctaaca tgattagatt tggattgagg gcgcgtgcag
    32641 ccttgtaagc ttcttcgata gaagcggcgt catggtctcc catcatatcg aagcggaagc
    32701 catccacttt gtaggtatca actaggtatt tgatagagtc aactaggagg cgtttggtca
    32761 tatggtgggt tgtccccaag cgtccaccac caaagctagt tcgaggtgtg ccatcggcat
    32821 ccataaagtg gtagtagttt ggctctaggt cttcaaagat atcgactttg gctgtgtggt
    32881 tataaacgac atctaggata gctcccatac cacgtttgtg gatttcgttg atgaggtttt
    32941 taaattctgc gattcgtttt tctggattct taggatcgct tgagtacata ccagtcaagg
    33001 agaagtagtt ttgagggtca tatccccagt tgtagttgct gttgcttgaa gcatagtcag
    33061 acaagcgttc atggtttttc aattcattga caaagtagta agacaagact ggaaggagct
    33121 ggatatgggt tacacccaag tctttgagat agtctagttt ttcaatgaag gcttcaaaag
    33181 tcccaaatgg tttggtcaag tcttttgcaa tggcaggatc tgaagtgaag tcacgcacat
    33241 gagcttcgta gataacggcg tcttcacgag tcttgaaatt gtgaatctta ccataagtca
    33301 agtcttgagg tccgagttta gctggatcta caaaggcggc tttagccact ttatgggcat
    33361 cgtcaatctt ggcatcgttg ctattccaag cagcaagaga tttagcgtaa ggatcgagtg
    33421 caagaacagt tttaccttga cgctcgattt ggtattgata atagtagcca gtgaaatctg
    33481 tgattccgag tttgtttgtg ctgtctagag tttgtttcca agttcctctt tccccttttt
    33541 cgagagcgac agttccaact actttgtcag ggtcattctt gtcgtagaca acaacagaaa
    33601 ccttatcagc acttggtgac caaagggtca aatcaacttg ttttccttct tcttttaggt
    33661 cagctcccag tttgccatca tagctgtatg tctcatcttt caggcgccag cttgttttgg
    33721 tagtgaattg gtcggaattg tagctaacag tataaggatg ttttgtgtca gagaaatctc
    33781 cgctgtaggt cactttctta ccagcttcat cgattgcaac atcggtaata gttaccttgt
    33841 ttcctaggtg attagtgatg ttggagtgtt tgaggatatc ttctttttta gcaccgacaa
    33901 gtgttgaaaa gctactttca atgctagaag tgcctacgtg ttgggctcct gtcatacgga
    33961 tatcatggac atagtatgga tttgtgtaaa tcgattcatc atcgtctttt aggaaaattt
    34021 ggctatgatt tttcaaatct gtgaacttat aattttcttt acggattttc acgtcgtctc
    34081 cttgtttgct ctcatctagt aataaaaatc caaattctct tgcggcttca ttaagaggaa
    34141 tgtcgatata gcggccatat ttgcctgtag ccgtaaagtc tgttccgtca ggccattgag
    34201 cgctacttgg atttttcaca tctccccagt accagagaga tttcttgtca tagttgccat
    34261 ctgtgcggta gtagttgacg cgaacagttc ctgcaggctg tggctcgtaa gagaaaacct
    34321 tgtaatcttg gtctaaccaa gcttcgttca tttttggaac tagtttttct acagatttat
    34381 cgccggttag attttttcca gctgtattgt tgatgaggaa gctaattttc ttggcttgtt
    34441 ctccctttaa tttgacatct aggtaatagc cgtagtcatc tttcttggca tccttgaagg
    34501 acaaagctcc gtttggccag ttttcagatg gtttttcaac atcgtcccaa gtccatagtc
    34561 cttgagcatc cttgttttct tcaggaagtt ttttgacatg gatacggaag tagttatctt
    34621 cgatgggctc ttctgcctta gtttcagttg ttactggact agtagaagta gttggctcac
    34681 ttgaacgatc ttgtccagtt tgtggtgctg gatcggctgg gcttgcagca ggagttgttg
    34741 gctctgttgc aggtttttct tctgttttct ctagggaagc gtttgcattt ccaagtgaag
    34801 aaatatcact tttgttctta ccagagccag ctgctgtatc agtaagaggt tgggcaaggg
    34861 tggttgtatt tctgttgttg ggttcgttag tggttggtgt actttcgtcg gatgagatag
    34921 ttggtgtagc catggcaagc aagacaaggc ttgcgccgat aaggacagaa ccagtcccat
    34981 ttttgaggga acggatgctg tagaccattt ttttctcagt gtgagatggt gtttttctca
    35041 taatgattct ccaatcaata aatttctata tcagtatagc atgtagtaaa acaatatgca
    35101 agcgttttct ttgatttgtg aaaaaaattc ttacttttga gaagttttct gtactatttt
    35161 atatatcagt ataaatgacg gagataaaaa tgtcacataa gccaagccgt attattagga
    35221 agatgatgtg ttcccagcta tttttattca gaaattgatc tctaacatta ccaataaaaa
    35281 agaaaaatat cttgacaaac aagggaaaat tttgttacaa taatagacgg tactttttac
    35341 ttttggtctc tcaagagtgt acagggacgt gctgacaaat gttgcaaaag tacacacaga
    35401 tgatatctgt caccaagtgt atcatcacca aaaataaaaa aacacaggag aatgtagatg
    35461 cctacaatta accaattggt tcgcaaaccg cgtaaatcaa aagtagaaaa atctaaatca
    35521 ccagctttga acgttggtta caatagtcat aaaaaagttc aaacaaacgt ttcttcacca
    35581 caaaaacgtg gtgttgcaac tcgtgttgga acaatgacac ctaaaaaacc taactcagcc
    35641 cttcgtaaat tcgctcgtgt acgtttgagc aaccttatcg aagttactgc ctacatccca
    35701 ggtatcggac acaacttgca agagcacagc gtggtgcttc ttcgcggtgg acgtgtaaaa
    35761 gaccttccag gggtacgtta ccatatcgtc cgtggtgcac ttgatactgc aggtgttaac
    35821 gatcgtaaac aaggtcgttc taaatacggt actaaacgtc caaaagcata aggaaagggg
    35881 ataaagagaa atgagtcgta aaaatagagc tccaaaacgt gacgtattgc cagatccgct
    35941 atacaattca caactagtta ctcgtcttat caaccgcgtt atgcttgatg gtaaacgtgg
    36001 tactgctgct tcaatcgttt acggtgcttt tgagcaaatc aaagaagcta ctggcaacga
    36061 tgcacttgaa gtatttgaaa cagctatgga aaacatcatg cctgtacttg aagtacgtgc
    36121 acgtcgtgtt ggtggttcta actaccaagt cccagttgaa gttcgtccag aacgtcgtac
    36181 aacacttgga cttcgttggt tggtaacaat cgctcgtctt cgtggtgaac acacaatgca
    36241 agaccgtctt gcaaaagaaa tcttggatgc tgctaacaac actggtgcag ctgttaagaa
    36301 acgtgaagat actcaccgta tggctgaagc taaccgtgca ttcgcacact tccgttggta
    36361 agataggatg cgaaagcgtt aagaaagtcc cagagaaaat agggaatcga agcaggttgc
    36421 ggttgcaacc aatgagattc atctttttct ccagactttt agcttgagct caactaaatc
    36481 atgatgctag gcacggtaag gatgcaaggt gaaaatagga aactgacgca gtattcaacg
    36541 aatacaagga gttttatctt tttcacgcag catcccgttc cagctcacat cggctaacta
    36601 actttagccc gggttcaaat tagctaaatc gattagtatt agctataact cagcttacca
    36661 tctcgtaagt tgaaaccaac aatagcatga aaacattgag aacgggtagg tcctgcctat
    36721 ccgtttttat taaaatcgtg ttataataga atagaaatca aaaataaata ggagaaacaa
    36781 acctcatggc acgcgaattt tcacttgaaa aaactcgtaa tatcggtatc atggctcacg
    36841 tcgatgccgg taaaacaaca actactgagc gtattcttta ctacactggt aaaatccaca
    36901 aaatcggtga aactcacgaa ggtgcgtcac aaatggactg gatggagcaa gagcaagaac
    36961 gtggtatcac gatcacatct gctgcgacaa cagctcaatg gaacaaccac cgcgtaaaca
    37021 tcatcgacac accaggacac gtggacttca caatcgaagt acaacgttct cttcgtgtat
    37081 tggatggtgc ggttaccgtt cttgactcac aatcaggtgt tgaacctcaa actgaaacag
    37141 tttggcgtca agcaactgag tacggagttc cacgtatcgt atttgccaac aaaatggaca
    37201 aaatcggtgc tgacttcctt tactctgtaa gcacacttca cgatcgtctt caagcaaatg
    37261 cacacccaat ccaattgcca atcggttctg aagatgactt ccgtggtatc attgacttga
    37321 tcaagatgaa agctgaaatc tatactaacg accttggtac ggatatcctt gaagaagaca
    37381 tcccagctga ataccttgac caagctcaag aataccgtga aaaattgatt gaagcagttg
    37441 ctgaaactga cgaagaattg atgatgaaat acctcgaagg tgaagaaatc actaacgaag
    37501 aattgaaagc tggtatccgt aaagcgacta tcaacgttga attcttccca gtattgtgtg
    37561 gttcagcctt caaaaacaaa ggtgttcaat tgatgcttga tgcggttatc gactaccttc
    37621 caagtccact tgacatccca gcaatcaaag gtattaaccc agatacagac gctgaagaaa
    37681 ctcgtccagc atctgacgaa gagccatttg cagctcttgc cttcaagatc atgactgacc
    37741 cattcgtagg tcgtttgaca ttcttccgtg tttactcagg tgttcttcaa tcaggttcat
    37801 acgtattgaa tacttctaaa ggtaaacgtg aacgtatcgg acgtatcctt caaatgcacg
    37861 ctaacagccg tcaagaaatc gacactgttt actcaggtga tatcgctgct gccgttggtt
    37921 tgaaagatac tacaactggt gactcattga cagatgaaaa atctaaaatc atccttgagt
    37981 caatcaacgt tccagaacca gttatccaat tgatggttga gccaaaatct aaagctgacc
    38041 aagacaagat gggtatcgcc cttcaaaaat tggctgaaga agatccaaca ttccgcgttg
    38101 aaacaaacgt tgaaactggt gaaacagtta tctcaggtat gggtgaactt caccttgacg
    38161 tccttgttga tcgtatgcgt cgtgagttca aagttgaagc gaacgtaggt gcgcctcaag
    38221 tatcttaccg tgaaacattc cgcgcttcta ctcaagcacg tggattcttc aaacgtcagt
    38281 ctggtggtaa aggtcaattc ggtgatgtgt ggattgaatt tactccaaac gaagaaggta
    38341 aaggattcga attcgaaaac gcaatcgtcg gtggtgtggt tcctcgtgaa tttatcccag
    38401 cggttgaaaa aggtttggta gaatctatgg ctaacggtgt tcttgcaggt tacccaatgg
    38461 ttgacgttaa agctaagctt tatgatggtt catatcacga tgtcgactca tctgaaactg
    38521 ccttcaagat tgcggcttca ctttccctta aagaagctgc taaatcagca caaccagcta
    38581 tccttgaacc aatgatgctt gtaacaatca ctgttccaga agaaaacctt ggtgatgtta
    38641 tgggtcacgt aactgctcgt cgtggacgtg tagatggtat ggaagcacac ggtaacagcc
    38701 aaatcgttcg tgcttacgtt ccacttgctg aaatgttcgg ttacgcaaca gttcttcgtt
    38761 ctgcatctca aggacgtggt acattcatga tggtatttga ccactacgaa gatgtaccta
    38821 agtcagtaca agaagaaatt attaagaaaa ataaaggtga agactaatcc gtcctcactc
    38881 tagaaggaag tcacttagtg gcttcctttt gtctttagaa aatacctcta aatatggtaa
    38941 aatagtagaa gaataatgtg aggaaaatga atgtcaaata gttttgaaat tttgatgaat
    39001 caattgggga tgcctgctga aatgagacag gctcctgctt tagcacaggc caatattgag
    39061 cgagttgtgg ttcataaaat tagtaaggta tgggagtttc atttcgtatt ttctaatatt
    39121 ttaccgattg aaatcttttt agaattaaag aaaggtttga gcgaagaatt ttctaagaca
    39181 ggcaataaag ctgtttttga aattaaggct cggtctcaag aattttcaaa tcagctcttg
    39241 cagtcctact atagggaggt tttctctgaa ggtccatgtg ctagtcaagg ttttaagtcc
    39301 ctttatcaaa atttgcaagt tcgtgctgag ggtaatcagc tatttattga aggatctgaa
    39361 gcgattgata aggaacattt taagaagaat catcttccta atttagccaa acaacttgaa
    39421 aagtttggtt ttccaacttt taactgtcaa gtcgagaaga atgatgtctt gacccaagag
    39481 caggaagagg cctttcatgc tgaaaatgag cagattgttc aagctgccaa tgaggaagcg
    39541 ctccgtgcta tggaacaact ggagcagatg gcacctcctc cagcggaaga gaaaccagtc
    39601 tttgattttc aagcgaaaaa agctgcagct aaacccaagc tggataaggc ggagattact
    39661 cctatgatcg aagtgacgac agaggaaaat cgtctggtat ttgaaggggt tgtttttgat
    39721 gtggagcaaa aagtgactag aacaggtcgt gttttaatca actttaaaat gacggactat
    39781 acttcaagtt tttctatgca aaagtgggtt aaaaacgagg aagaggccca gaagtttgac
    39841 ctcatcaaga agaattcttg gctccgagtt cgagggaatg tggagatgaa taatttcaca
    39901 cgcgatttga ctatgaacgt acaggatctg caggaagttg ttcactatga gcggaaggat
    39961 ttgatgccag aaggtgagcg tcgggttgag tttcatgctc atactaacat gtcgactatg
    40021 gatgctttgc cagaggtcga agagattgtt gcaacagctg ctaagtgggg acacaaggcg
    40081 gttgctatca cggaccatgg gaatgtccag tcctttccac atggctataa ggcggctaag
    40141 aaagcgggaa tccagctgat ctatggaatg gaagccaata tcgtggagga ccgtgtccct
    40201 atcgtctata acgaagtgga gatggacttg tcagaagcaa cctacgtggt ctttgacgtg
    40261 gaaacgacgg gactttcagc tatctataat gacttgattc aggttgcggc ctctaagatg
    40321 tacaagggga atgttattgc tgaatttgat gaatttatca atcctgggca tcccttgtca
    40381 gcttttacta cagagttaac tggaattaca gatgatcatg tcaaaaatgc caaaccacta
    40441 gaacaagttt tgcaagaatt ccaagaattt tgcaaggata cggtcctagt tgcccacaat
    40501 gctacctttg acgttggctt tatgaatgct aattatgagc gtcatggtct tccaaagatt
    40561 agtcagccag ttattgatac gctggagttt gctagaaacc tctatcctga gtataaacgc
    40621 catggtttgg ggcctttgac caagcgtttt ggtgtggcct tggaacatca tcacatggcc
    40681 aactacgatg cggaagcgac tggtcgtctg cttttcatct ttatcaaaga ggtagcagaa
    40741 aaacatggtg tgaccgattt agctagactc aacattgatc taatcagtcc agattcttac
    40801 aaaaaagctc ggatcaagca tgcgaccatc tatgtcaaga atcaggtagg tctaaaaaat
    40861 atctttaagc tggtttcctt gtctaatacc aagtattttg aaggagtgcc acggattccg
    40921 agaacggttc tagatgccca tcgagagggc ttgattttag gttcagcctg ttcagagggt
    40981 gaagtttttg acgtggtcgt ttctcaaggt gtggatgcgg cggttgaggt ggccaagtat
    41041 tatgacttta tcgaggtcat gccaccggct atctatgcgc ccttgattgc caaagagcag
    41101 gtcaaggata tggaggaact ccagaccatt atcaagagtt tgatagaggt tggagatcgc
    41161 cttggcaagc ctgttctggc tacgggaaat gttcactata tcgaaccgga agaagagatt
    41221 tatcgtgaaa ttatcgtccg tagtttggga cagggtgcga tgattaaccg aactatcggt
    41281 catggtgaac atgcccaacc agcaccactt ccaaaggctc attttcgaac gactaatgag
    41341 atgttggatg aatttgcctt tttgggagag gaactggctc gtaaactggt tattgaaaac
    41401 accaatgcct tggcagaaat atttgaaccc gttgaagtcg ttaagggtga cttgtatacg
    41461 cctttcatcg acaaggctga agaaacagtt gctgagttga cctataagaa agcttttgag
    41521 atttatggaa atccgctgcc agatattgtt gatttgcgga ttgaaaaaga attaacatcc
    41581 atactgggga atggatttgc tgtgatttat ctggcatcgc agatgctggt gcaacgttct
    41641 aatgaacggg gttatttggt tggttctcgt gggtctgtcg gatctagttt cgttgcgacc
    41701 atgattggga ttacggaagt caatcctctc tctcctcact atgtctgtgg tcagtgtcag
    41761 tacagtgagt ttatcacaga tggttcgtac ggttcaggat ttgatatgcc ccataaggac
    41821 tgtccaaact gtggtcacaa actcagtaaa aacggacagg atattccgtt tgagaccttc
    41881 cttggttttg atggggataa ggttcctgat attgacttga acttctcggg agaagatcag
    41941 cctagcgccc acttggatgt gcgtgatatc tttggtgaag aatatgcctt ccgtgcggga
    42001 acggttggta cggtagctgc caagactgcc tatggatttg tcaagggtta cgagcgagat
    42061 tatggtaagt tttatcgtga tgcagaagta gaacgcctcg ctcaaggagc ggcgggtgtc
    42121 aagcggacaa caggccaaca cccgggggga atcgttgtta ttccgaacta catggatgtc
    42181 tacgatttta cgcctgtcca gtatccagca gatgatgtca cggctgaatg gcagaccact
    42241 cactttaact tccacgatat cgatgagaac gtcctcaaac tcgatgtact gggacatgat
    42301 gatccgacca tgattcgaaa acttcaggat ttgtctggta ttgaccctaa taaaattcct
    42361 atggatgacg aaggcgtgat ggcactcttt tctgggactg atgtgctagg ggtaacacct
    42421 gaacaaattg gaacgcctac gggtatgttg gggattccag agtttggaac aaatttcgta
    42481 cgtggaatgg tagacgaaac ccatccgaca acctttgcgg aattgcttca gctgtctggt
    42541 ctgtcccacg gtactgacgt ttggttgggg aatgctcagg atctgattaa gcaaggaata
    42601 gcggacctat cgactgttat cggttgtcgg gacgacatca tggtttacct catgcatgcg
    42661 ggtctggaac ctaagatggc ctttaccatt atggaacggg tacgtaaggg tttgtggcta
    42721 aagatttcag aagaggagag aaatggctat atcgaagcaa tgaaggctaa taaggtgcca
    42781 gagtggtata tcgaatcctg tgggaaaatt aagtacatgt tccctaaggc ccatgcggca
    42841 gcctacgtta tgatggcctt gcgtgtagct tacttcaagg ttcaccatcc tatttattac
    42901 tactgtgctt acttctccat tcgtgctaag gcttttgata tcaagaccat gggtgcgggc
    42961 ttggaggtca tcaagcgcag aatggaagaa atctctgaaa aacggaagaa caatgaagcc
    43021 tctaatgtgg aaatcgatct ctatacaact cttgagattg tcaatgagat gtgggaacga
    43081 ggtttcaagt ttggtaaatt agatctctac tgtagtcagg cgacagagtt cctcatcgac
    43141 ggggataccc ttatcccacc atttgtagca atggatggtc tgggagagaa cgttgccaag
    43201 caactggtgc gggcgcgtga agagggagaa tttctctcta aaacagaact acgcaagcgt
    43261 ggtggactct catcaacctt ggttgaaaag atggatgaga tgggtattct tggaaatatg
    43321 ccagaggata accagttgag tttgtttgat gagttgtttt aaaaaattgc ttaataatct
    43381 attaaaagag gctaacgtat atccaataga tttacattag ctttcttttt tgttaaaata
    43441 gtctatggaa agagggtgag agtatgtcaa agatgagtat aagcatccgt ctggatagtg
    43501 aggttaagga gcaggcccaa caggtgttta gtaatctggg aatggatatg acaacagcta
    43561 ttaatatttt ccttcgtcag gcaattcaat atcagggact accttttgat gttagactag
    43621 acgaaaatcg gaagttgctc caagcgttaa cggatttaga ccaaaatcgt aatatgagcc
    43681 agtcttttga atcagtctca gatttgatgg aggacttacg tgcttaagat tcgttatcat
    43741 aaacagttta aaaaagattt taagttggct atgaagcgtg gtttgaaggc agaattatta
    43801 gaagaagttt tgaattttct ggttcaagaa aaagaacatc ctgccagata tcgtgatcat
    43861 tcattgacgg catccaagca ttttcaagga gttcgtgaat gccataccca gccagattgg
    43921 cttttggttt ataaagtaga caagtcggaa ttgattttaa atttgctgag gacaggcagt
    43981 cacagtgatt tattttaatc tattttaagg gggttctcat gaaactaaga atatttgcgg
    44041 aagataagcc ggctaagaag gtatttgaat atcaattaga acttgctgat cgtacaattc
    44101 ttctatcgac agcactcttg tcaggtgcta ttgctttagc aggaatcttt tctgctttga
    44161 gagaaaaata aaaatagaaa agagaaaaca gaatggtttt accaaatttt aaagaaaatc
    44221 tagaaaaata tgcgaaattg ttggttgcga acggaattaa cgtgcaacct ggtcacactt
    44281 tggctctctc tattgatgtg gagcaacgtg aattggcaca tctaatcgtg aaagaagctt
    44341 atgccttggg tgcgcatgag gtcatcgttc agtggacaga tgatgtgatt aaccgtgaga
    44401 aattcctcca tgccccgatg gagcgtttgg acaatgtgcc agaatacaag attgctgaga
    44461 tgaactatct cttggagaat aaggctagcc gtcttggagt tcgttcatct gatccaggtg
    44521 ccttgaacgg agtggacgct gacaagcttt cagcttctgc taaagctatg ggacttgcca
    44581 tgaagcctat gcgtatcgca actcaatcta acaaggttag ctggactgta gcagctgcag
    44641 caggacttga gtgggctaag aaagtcttcc caaatgctgc gagcgacgaa gaagcagttg
    44701 atttcctttg ggaccaaatt ttcaaaactt gccgtgtcta cgaagcagat cctgttaagg
    44761 cctgggaaga gcatgcagct atcttgaaga gcaaggccga tatgcttaat aaggagcaat
    44821 tttcagccct tcactacaca gcgccaggaa cagatttaac acttggtttg ccaaagaacc
    44881 atgtttggga atcagctggt gctgtcaatg cacagggcga aggattcttg ccaaatatgc
    44941 cgacagaaga ggtcttcaca gcacctgact tccgtcgtgc agatggttat gtcacttcta
    45001 caaaaccgct tagctacaac ggaaatatta ttgaaggcat taaggtgacc tttaaggatg
    45061 gacaaatcgt agatatcact gctgagaagg gtgatcaggt tatgaaagac cttgtctttg
    45121 aaaatgcggg tgcgcgtgcc ttgggtgaat gtgccttggt accagatcca agtccaattt
    45181 ctcagtcagg cattaccttc tttaacaccc ttttcgatga aaatgcgtca aaccacttgg
    45241 ctatcggtgc agcctatgcg actagcgttg ttgatggagc ggagatgagc gaagaggagc
    45301 ttgaagctgc agggcttaac cgttcagatg ttcacgtaga ctttatgatt ggttctaacc
    45361 aaatggatat cgatggtatt cgtgaggatg gaacgcgggt acctcttttc cgtaatggga
    45421 attgggcaaa ttaaggagat aatatgttag gaagtatgtt cgttggtctc ctagtgggat
    45481 ttttagcagg tgctatgacc aatcgtggag agcgaatggg atgttttgga aaaatgtttc
    45541 tcggttggat cggagccttt ctaggtcact tgctctttgg aacttggggg ccagttttat
    45601 caggaacagc tattatccca gctgttttag gtgccatgat tgtcttagct attttttgga
    45661 gacgaggaag ttaatttcct aaatctgata ctcaatgaaa atcaaagagc aaactaggaa
    45721 actagccgca ggttgctcaa agcactgctt tgaggttgca gatagaactg acgaagtcag
    45781 taacatatat gcggcaaggc gacgttgacg cggtttgaag agatttttga agagtatgaa
    45841 acgaaaagga ggttggtcat tgtactagcc tccttttgat atgatataat agttctatga
    45901 gattagataa atttttagtt gcctgtgcgg tgggaagtcg gactgaggtc aaaaacttgc
    45961 tcaaggctgg gcgcgtgact gtaaatggta aaaaagaaaa atcagctaaa ttgcagattg
    46021 atgaaaaaat agatgagatt cgctttgatg ggcaagtgtt ggagtatgaa gagtttgtct
    46081 actacatgat gaacaagccc aaaggagtta tctcagcgac tgaggatccc aagcacagaa
    46141 ccgttctgga cttgttggat gacttggcgc ggagtaagga agtttttcca gtaggacgct
    46201 tggatattga cacgcatggt cttttgctct tgaccaataa tggtcagctg gctcatgttc
    46261 ttctttctcc caagcgtcat gtggacaaga cttatcaggc tcaggtcaag ggaattatga
    46321 cccaagaaga tgtggagaca tttatcaagg gcattccgct caaagacttt acctgtcagc
    46381 ccgctagact ggagattctt tccacagatg cagaaaagaa tcagagccaa atccgtgtga
    46441 ccattgcaga agggaagttt catcagatca agcgtatggt gggctactgt ggcaaggaag
    46501 tggtggactt gcaacgattg actatgggaa ctttagtatt agatgagaac ctggaacgag
    46561 gggaatggcg tcgcttgacc aaggaagaat tagaaattct ccgcgctaat attatttaat
    46621 ttagtttaat actcaatgaa aatcaaagag caaactagga aactagccgc aggctgtact
    46681 tgagtacggc aaggcgacgt tgacgtggtt tgaagagatt ttcgaagagt ataaattcga
    46741 aaaaggtgag ggagaatgtc cttacctttt atgtttttta gttgcttcct ttgtgaaaag
    46801 agttataata gactgtagaa taaaaggagg aatctatgaa cgcgattcaa gaatcattta
    46861 ctgataaact atttgccaac tatgaagcaa atgtaaaata ccaagcgatt gaaaatgctg
    46921 ccagccacaa cggaattttt gcagctctgg aacgtcgcca aagccatgta gacaacacac
    46981 ctgttttctc attggattta accaaggaca aggtcactaa ccagaaagcg tctggtcgtt
    47041 gctggatgtt tgcggctctc aacaccttcc gccacaaact catctcgcaa tacaaattgg
    47101 agaactttga gttgtcacaa gcccacactt tcttctggga taagtatgag aaatcaaact
    47161 ggttcttgga gcaagtcatt gcgacttcag accaagaatt gactagccgc aaggttagct
    47221 tcttactcca aacacctcaa caagatggtg gtcaatggga tatggtcgtt tccctctttg
    47281 aaaaatacgg tgtcgtgcct aagtcagttt atcctgagtc tgtttcatct agcagcagtc
    47341 gtgagctaaa tgcgatcctt aataaattgc ttcgtcaaga tgctcaaatc ttgcgtgatt
    47401 tgcttgtttc tggtgcagat caagtgactg ttcaaactaa gaaagaagac ctcttgcaag
    47461 aaatctttaa ctttcttgct atgtcattag gacttccacc acgcaagttt gactttgctt
    47521 atcgcgataa agataacaac tacaaaagtg aaaaaggaat cacaccacaa gagttctaca
    47581 agaaatatgt caatcttcct ttagaagact acgtttctgt tatcaatgct ccaactgctg
    47641 ataaacctta cggaaaatct tacacagttg agatgttggg gaatgtggtt ggtagccgtg
    47701 cagttcgcta catcaacgtt ccaatggagc gcttgaaaga attggcgatt gcccaaatgc
    47761 aagcaggtga gactgtttgg tttggttctg atgtcggcca gctcagcaac cgtaaggctg
    47821 gcatccttgc gacagatgtt tatgactttg aatcaagcat ggacattaaa cttactcaag
    47881 acaaggctgg acgtttggac tatagtgaaa gcttgatgac ccacgccatg gtcttgacag
    47941 gtgttgactt ggacgaaaat ggtaaatcaa ccaagtggaa ggttgaaaac tcatggggag
    48001 acaaggtcgg tacagatggt tactttgttg cctcagacgc ttggatggac gaatacacat
    48061 accaaatcgt tgttcgtaag gaattgctga cagcagaaga acaagctgcc tatggagcag
    48121 aaccaatcgt acttgcacca tgggatccaa tgggagcctt ggctgaataa aagcatagaa
    48181 aaaaggaatc agattttaga acctggttcc tttttagttg cttgattaca tgatgtgaag
    48241 aacatgtgcc acaataccca ctgcgaagag ggcaaggata atagtgattg gagatacttt
    48301 tttcttaagt aagtacatgc aaagtaaagt aaggagtagt cctgataatc caggaatcaa
    48361 catatccaag ttttgttgga aagtagtaac tttttcagga gtttgagaca atccttgtcc
    48421 tacttgtgcg aatgcttctt ggataccttt agacccttct ggcaatttat cccaatggat
    48481 ataagccttt tcatctagtt gaactttaga aacatcgaaa gcaaatttaa tatttaccca
    48541 gcgttgaaca aggacagcaa gaatgaacat cccaaggata gaagctcctt tagtgatatc
    48601 ttgaaggata ccaccagaca tatctttagt gatttctgat ccagccttgt atccaatctc
    48661 ttgaacatac cacaagaatg acatacgaat caagttccat gcaacaaaga agaggagtgg
    48721 acccaagata ttgccagtaa gggcaagtga agcaccgaga gatccaagga ttgggcgtac
    48781 tgtaaaccag aatactgggt caccgatacc agcaagaggt cccatcatac cgattttaac
    48841 cccttggata gcagcgtcat cgatttccac accgttagca cgttcttctt caagcgcaag
    48901 agtaaccccc atgactggag cagctacgta tggatgagtg ttgaagaact caaggtgacg
    48961 ctcaagagca gcgatttgat cttctttttt agtatagagt tttttgatag ctggaatgag
    49021 tgtataagcc cagcccaagt tttgcatccg ttcaaagttc caagaccctt gtaagaaggt
    49081 tgaacgccac caaacttttt tacgatctga tttagttaat tgaagttttt cagtcatgat
    49141 gttttcagtc ctttcttatc ttagtagtct tctaggatat cgccgattgg gtcgttagaa
    49201 gttgcggctc ctccgccacc atttccacca gttttagaaa ggtgaaggta gataagagcg
    49261 atagcaacac cgatagcacc gaatccgatt agagtaatat ctgacacagc agcgagaacg
    49321 aaaccaagag cgaagaatgg ccatacttca cgagttgcca tcatgttgat aaccatggcg
    49381 taaccaacgg caacgaccat accaccaccg atagccatac catctttgag ccagtctggc
    49441 atggcactaa ggatactttg tacagtttca gttggtacca taaggagaag agctgcagga
    49501 agcgcgatac gaagtccttg gaaaagtagc gcaatgaaat gcgcacgctc cacagcgccg
    49561 aagtcacctt ttttagcggc agcatctgca gtatgaacca aaccaactga aattgtacga
    49621 acaatcattg tcaagaaaag tccagctacg gcaagaggga tagcaaccgc ttgggcaaca
    49681 ccgataccag tcttggtaaa gtcaccacca agaaccatga taatggcagc agcgacagaa
    49741 gcaagtgcag catcaggagc gatagcagca ccgatatttg accaaccaag ggcaatcatt
    49801 tgaagcgatc caccgaggat aatccctgct tccaagtgac ctgttacaag cccaataagg
    49861 gtacaggcta caagtggttg gtgaaattgg aactggtcga ggatgccttc aagacctgca
    49921 aagaaggcta caacgactac taaaaccata gaaataatag acatgtttaa aatcctttca
    49981 taaataatgg cttatttgac attggctttg ttaatcaagt caaacaaatc ttttttagaa
    50041 tcatttggta ctttacggac atcaaattca acacccaagt cacgcatttt ttcaaatgta
    50101 gcaacatctt ctttgtccat agacaaaacg gtattgacca atgttttacc tgttgagtga
    50161 gccatagaac caacgttaag agtcttgatt ggcacgccgc cttcgatggc acgaagggca
    50221 tcttgaggtg tttcaaacaa gataagggca tgtgtttctc caaaacgtgg gtcttttgaa
    50281 atctcaatca gtttttgaat tggaaccacg ttagccttga cattacctgg agctgcttgt
    50341 ttaatcaatt ctttacgaag gtcgtcttta gccacgttat ctgaagcaac gatgatacga
    50401 tttgcttttg aatctggagt ccaagcagtt gcaacctgac cgtgaagtag acgtgtgtca
    50461 agacgggcaa gattgatttt caatttaccg tctccgataa cagttccttc tgggatagca
    50521 gtttgggcaa ctggagcagc tgcagcgctt gcaacttctt caactggatt tagctcttct
    50581 ggaagagctt tgatgccatc tttggcttct ttaatgatat tagcagcgac tttttctaca
    50641 cctgcagcag cgtccatgag gcgctctgtg taggcttgaa tcaacatcgg taagttaagt
    50701 cctgtgatga tggcaaactt acgctcagga ttttctccca tcacgcgact agcttggtta
    50761 aatggagaac cactccaaag gtcagccaaa actagaacct catcttctgc gtcaaatgca
    50821 gcaacagcgt tattaaactt agcgtataga tcatcaggac cttcatttgg cataaaggtc
    50881 acaacttgaa ccttttcttg ttcaccaaag atcatagatc ctgactgatg aatacccgca
    50941 gcaaattcgc cgtggctcgc aataatgatt ccgatactca ttattgtcat tcctcctttt
    51001 ttgttttagt tttcatttaa gaaaacttta agactgttta agtataaacc gttttcata
//
LOCUS       DAVKMJ010000011        48823 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000011 DAVKMJ010000000
VERSION     DAVKMJ010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48823
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.011"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..137)
                     /locus_tag="VW348_000626"
     CDS             complement(<1..137)
                     /locus_tag="VW348_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9745569.1"
                     /translation="MNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRLLLAYQQK
                     G"
     gene            314..1759
                     /gene="cps4A"
                     /locus_tag="VW348_000627"
     CDS             314..1759
                     /gene="cps4A"
                     /locus_tag="VW348_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     Cps4A"
                     /protein_id="HEU9745570.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYLNLVITALVLLVALLGLLLIIYKKAEKFTIFLLVFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSDIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAVYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLADGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNMPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLAVVKAAIQDVMEGR"
     gene            1761..2492
                     /locus_tag="VW348_000628"
     CDS             1761..2492
                     /locus_tag="VW348_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEU9745571.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKVKELFVDNPRKIIMDQLI"
     gene            2501..3193
                     /gene="cpsC"
                     /locus_tag="VW348_000629"
     CDS             2501..3193
                     /gene="cpsC"
                     /locus_tag="VW348_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HEU9745572.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSMTRIYVVNRNQGEKSGLTNQDLQAGSSLVKDYREIILSQDVLEEVVSDLKLD
                     LTPKDLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPATSPSSPNIKRSTLIGFLAGVIGTSVIVLILELLDTRVKRPKDIEDTLHMT
                     LLGIVPNLNKLK"
     gene            3203..3892
                     /gene="cpsD"
                     /locus_tag="VW348_000630"
     CDS             3203..3892
                     /gene="cpsD"
                     /locus_tag="VW348_000630"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HEU9745573.1"
                     /translation="MPTLEIAQKKLEFVKKAEEYYNALCTNIQLSGDKLKVISVTSVN
                     PEEGKTTTSVNIARSFARAGYKTLLIDGDTRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGTVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTAPIGIVI
                     DAAIITQKCDASILVTATGEVNKRDVQKAKQQLEQTGKLFLGVVLNKLDISVDKYGVY
                     GFYGNYGKKII"
     gene            3903..5270
                     /locus_tag="VW348_000631"
     CDS             3903..5270
                     /locus_tag="VW348_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU9745574.1"
                     /translation="MDEKGLKIFLAVLQSIIVILLVYFLSFVRETELERSSMVILYLL
                     HFFVFYFSSYGNNFFKRGYLVEFNSTIRYIFFFAIAISVLNFFIAERFSISRRGMVYF
                     LTLEGISLYLLNFLVKKYWKHVFFNLKNSKKILLLTVTKNMEKVLDKLLESDELSWKL
                     VAVSVLDKSDFQHDKIPVIEKEKIIEFATHEVVDEVFVNLPGESYDIGEIISRFETMG
                     IDVTVNLKAFDKNLGRNKQIHEMVGLNVVTFSTNFYKTSHVIAKRIIDIMGALVGLIL
                     CGLVSIVLVPLIRKDGGSAIFAQTRIGKNGRQFTFYKFRSMCVDAEAKKRELMEQNTM
                     QGGMFKVDDDPRITKIGRFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYVQYTSE
                     QKRRLSFKPGITGLWQVSGRSKITDFDDVVKLDVAYIDNWTIWKDIEILLKTVKVVFM
                     RDGAK"
     gene            5274..6017
                     /locus_tag="VW348_000632"
     CDS             5274..6017
                     /locus_tag="VW348_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HEU9745575.1"
                     /translation="MRDRIQLLGVTIDLLTMNETIDIVEQYVLEKRPLHLMGVNADKI
                     NQCHTDEKIKKIVNESGIINADGASVVLASKFLGTPVPERVAGIDLMQCLLELSNKKG
                     YSVYFFGAKEEVLQDMLKVFKRDYPNLIVIGHRNGYFSEEDEQAIQEDIREKNPDFVF
                     IGITSPKKEYIIQKFMDSGVNSVFMGVGGSFDVLSGHIQRAPLWMQKSNLEWLFRVAN
                     EPKRLFKRYFVGNISFIGRVLKAKRGVKY"
     gene            6014..6838
                     /locus_tag="VW348_000633"
     CDS             6014..6838
                     /locus_tag="VW348_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LicD family protein"
                     /protein_id="HEU9745576.1"
                     /translation="MNQTEMIRLIQKVELDAIKEFKKICEENDIDFFLRGGSVLGAVK
                     YDGFIPWDDDMDIAVPREAYDKLPSVFKDRIIAGKYQVLTYQYCDTLHCYFPRLFLLE
                     DERKRLGLPRNTNLGLHLIDIIPLDGAPNHSVLRKIYFGKVYWYRFLASLGTTYVGDH
                     VDMHSTKQKLIIGFFKKLGFAKLFPQNSVYRRLDNLYKKYDWKKQKYAGTINASLFAK
                     EVMPVEIWGEGVEKPFEDTFFKVPTEYDRYLKRLYGENYLYEEPSDDEKKSHLGGH"
     gene            6840..7718
                     /locus_tag="VW348_000634"
     CDS             6840..7718
                     /locus_tag="VW348_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9745577.1"
                     /translation="MFCYIILHYKVLEETISCVKSIKEGNYNAKQIVIIDNFSNNGTG
                     EKLQELYESDLEIDVLINHENAGFARGNNVAYQFAKEKYNPDFMVIMNNDIEIETENF
                     EKIVTDIYREEKFHLLGPDIFSTTYQLHQNPKRLTHYTYGEVKALNEKFKKGSQVSLA
                     LKIKCWLKASKVLRTAIYQNRRKKGSVDYRKQVENPILHGSFIVYSRDFIEKEEYAFN
                     PNTFFYYETEILDYEAELKGYKRIYTPKIRVLHHQNVATNQVYTNLLEKTLFSNKCNF
                     KSTSYFLKLMKENEDV"
     gene            7719..9056
                     /locus_tag="VW348_000635"
     CDS             7719..9056
                     /locus_tag="VW348_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HEU9745578.1"
                     /translation="MSYLFLLCLTLFLLTIFYFFAFIQDLIAPPVVMSVMFLISSVFA
                     LVNSKNWNIEYSGIAYILIISGIIIFSLPLMALKSPNFNTEVKIADRLIDIQFWKIAL
                     TIIIDLFILYLYRKEIYNLVLSNGYTGSNIQWFFRNATSYEGELTVRTFIRVLIRVID
                     VSAYIFGYTFINNFLIYRHKRPKDILLLVPLLIFISKTLISGGRQDIIKILIAYVIMM
                     YIQQKRKVGWNRVISHKYIHLGFVGLIAGIPAFYYSLFLAGRSTTRTLFESVSTYLGG
                     SIQHFNQYIENPLDPGEVFGSETLVPILNILGEMGLVNYRSTIHLEFRTLGVTVGNVY
                     TFFRRPLHDFGLVGMYVFVFAVGAFFAIYYLVLRKKQVGFNLDIHTIIYSYVFYWIFL
                     SSIEQYSFTMISLYTLVFIVLVYFMAIFYWCTDFKRGKLIFKISDSSIKLKEE"
     gene            9079..10500
                     /locus_tag="VW348_000636"
     CDS             9079..10500
                     /locus_tag="VW348_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745579.1"
                     /translation="MNTKIKNIITSFSYVISSNLLIVLTSSLVVLIFPKIMGVTEYSY
                     WQLYIFYLTYIGFFHLGWIDGIYLKYGGLEYTNLDRKQFYSQMILFSSFLMLISLVLF
                     TLNLITVRDENARYIYNMAIISMIVTNLRTLYVYILQMTNRLKDSSVILISDRVLYVL
                     LLFMFIVFGWHEYKVMIWADILGRTFSLMLSFWICKDIVFQPLSKFILDFKESLDNIR
                     VGINLMLSNIASSMIIGIVRMGIQWNWNIETFGKVSLTLSISNLLMTFINAIGLVIFP
                     LIKRTKTENLPKIYSNLRNALMLVMFAILLFYYPLKFILDIWLPAYKDALVFMALIFP
                     MSVYEGKMALVINTYLKAMRMEKDILKINALVMLTSMVVTLVTTLLLNNLGLTVVSIV
                     ILLALRSIIAELILSKKLKISVKQDIALELLMTIIFISSSWYLSIWIAVIIYLLAYTL
                     YLYLKHKDIRMYIEYFKNHKKIS"
     gene            10564..11652
                     /gene="wecB"
                     /locus_tag="VW348_000637"
     CDS             10564..11652
                     /gene="wecB"
                     /locus_tag="VW348_000637"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HEU9745580.1"
                     /translation="MKKIMLVFGTRPEAIKMCSLVNELRKQEDMKTVVCVTGQHKEMV
                     SPVLDLFGVQPDYDLEIMKANQNLFSITISILEKIKPVLEKEQPDIVLVHGDTTTTYA
                     AALAAFYLGIKVGHVEAGLRTYNLQSPFPEEFNRQSTSIIANYHFAPTELAKENLIKE
                     GRNNIYVTGNTVIDALTTTVQKDYTHPDLDLNDGNRLILLTAHRRENLGEPMRHMFRA
                     VKRVLNEYDDVKVIYPIHKNPLVRETATEIFGDTERIQIIEPLDVLDFHNFMNHSYMI
                     LTDSGGVQEEAPSLGKPVLVMRDTTERPEGVAAGTLKLVGTDEETIYQNFKMLLDDPE
                     EYKKMSQASNPYGNGDASKQIVRILRGI"
     gene            11691..12560
                     /gene="rfbA"
                     /locus_tag="VW348_000638"
     CDS             11691..12560
                     /gene="rfbA"
                     /locus_tag="VW348_000638"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEU9745581.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGLKLSYAEQPSPDGLAQAFIIGEEFISDDSV
                     ALILGDNIYHGSGLSKMLQKAASKESGATVFGYHVKDPERFGVVEFDQDMKAISIEEK
                     PEQPRSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKN
                     EYGQYLLRLIGEA"
     gene            12561..13157
                     /locus_tag="VW348_000639"
     CDS             12561..13157
                     /locus_tag="VW348_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEU9745582.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENIAEAEVSEADKHHPLLKDVKPLKKEDLE"
     gene            13167..14216
                     /gene="rfbB"
                     /locus_tag="VW348_000640"
     CDS             13167..14216
                     /gene="rfbB"
                     /locus_tag="VW348_000640"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEU9745583.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLAAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQAAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            14282..15133
                     /gene="rfbD"
                     /locus_tag="VW348_000641"
     CDS             14282..15133
                     /gene="rfbD"
                     /locus_tag="VW348_000641"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEU9745584.1"
                     /translation="MILITGANGQLGTELRYLLDERNEEYVAVDVAEMDITDAEMVEK
                     VFEEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTKNVARASEKHGATLVYISTD
                     YVFDGKKPVGQEWEVDDRPDPQTEYGRTKRMGEELVEKHVSNFYIIRTAWVFGNYGKN
                     FVFTMQNLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYLAENRKEFGYYHLSNDATEDT
                     TWYDFAVEILKDTDVEVKPVDSSQFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALQE
                     FYKQEVR"
     gene            15209..15643
                     /locus_tag="VW348_000642"
     CDS             15209..15643
                     /locus_tag="VW348_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9745585.1"
                     /translation="MLLVLVSLAHSFGSVSIIAHTIHQKFNLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSQLTYYWTF
                     LSGKAENQVITLYHHDQCRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            15716..15973
                     /locus_tag="VW348_000643"
     CDS             15716..15973
                     /locus_tag="VW348_000643"
                     /inference="COORDINATES: protein motif:HMM:NF015038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9745586.1"
                     /translation="MVNCEPLEAYRQLEEAELVGCWAHVRRKFFEVPPKQADKSSLGA
                     KGLAYCDQLFSLERDWEALPADERLQKRQEHLQPLMEDFFA"
     gene            16019..16165
                     /locus_tag="VW348_000644"
     CDS             16019..16165
                     /locus_tag="VW348_000644"
                     /inference="COORDINATES: protein motif:HMM:NF015038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9745587.1"
                     /translation="MEYSLKYEETFKTILKDGHLVLSNNLAERAIKSLVMGRSKRVQW
                     TLLA"
     gene            16236..16394
                     /locus_tag="VW348_000645"
     CDS             16236..16394
                     /locus_tag="VW348_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HEU9745588.1"
                     /translation="MSLLETAKRHQLNSEKYLSYLLECLPNEETLVNKEVLEAYLPWT
                     KVVQEKCK"
     gene            16593..18575
                     /locus_tag="VW348_000646"
     CDS             16593..18575
                     /locus_tag="VW348_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9745589.1"
                     /translation="MKSSKLLALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDGYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVMAPVNEEFLNSKGDDFAKATDPNSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHIDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPILYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            18875..24193
                     /locus_tag="VW348_000647"
     CDS             18875..24193
                     /locus_tag="VW348_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEU9745590.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQ
                     NDNAGKPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYD
                     KDGWFWEYKTPGNSTWYKGNRVAAPETGSINRLSITLKSDGQLNASNNDVNLFDTVTL
                     PAAVNDHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKV
                     TYDTIQSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKIN
                     ETTAEYLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLL
                     SSISFLGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVS
                     TDKLAAGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFP
                     EYTKELPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFG
                     SQAQNPFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDF
                     KTLIEKAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDA
                     AYDLAHGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRF
                     AIEWGHGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAA
                     NYPLLGGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDN
                     GSTYKWTPEMRVELVDANNNKVVVTRKSNDVNSPQYRKRTVTLNGRVIQDGSAYLTPW
                     NWDANGKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVK
                     DGKITLDLLANQPYVFYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEI
                     VKSQGANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKE
                     VTTYTNKSLALNYVKAYAHNTRRDNATVDNTSYFQNMYAFFTTGSDVSNVTLTLSREA
                     GDQATYFDEIRTFENNSSMYGENHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRT
                     HLSEKHDPYTQRGWNGKKVDDVIDGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYR
                     VTFEYEAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTG
                     AETGDTWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALK
                     NYLPTVAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTA
                     LVADDFASLTAPAQAQEGLANAFDGNVSSLWHTSWGGGDVGKPATMVLKEPTEITGLR
                     YVPRGSGSNGNLRDVKLVVTDESGKEHTFTATDWPNNNKPKDIDFGKTIKAKKIVLTG
                     TKTYGDGGDKYQSAAELIFTRPQVAETPLDLSGYEAALVKAQKLTDKDNQEEVASVQA
                     SMKYATDNHLLTERMMEYFADYLNQLKDSATKPDAPTVEKPEFKLRSLASEQGKTPDY
                     KQEIARPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(24360..26519)
                     /locus_tag="VW348_000648"
     CDS             complement(24360..26519)
                     /locus_tag="VW348_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HEU9745591.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(26516..27112)
                     /gene="recU"
                     /locus_tag="VW348_000649"
     CDS             complement(26516..27112)
                     /gene="recU"
                     /locus_tag="VW348_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEU9745592.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            27178..27705
                     /locus_tag="VW348_000650"
     CDS             27178..27705
                     /locus_tag="VW348_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEU9745593.1"
                     /translation="MATALVLGYSTFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            27775..28104
                     /gene="gpsB"
                     /locus_tag="VW348_000651"
     CDS             27775..28104
                     /gene="gpsB"
                     /locus_tag="VW348_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEU9745594.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            28125..28505
                     /gene="rnpB"
                     /locus_tag="VW348_000652"
     ncRNA           28125..28505
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VW348_000652"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            28590..29747
                     /locus_tag="VW348_000653"
     CDS             28590..29747
                     /locus_tag="VW348_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEU9745595.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARLPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFDEWNWISDRLIQEVRTEAAKKVERKLELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            29760..31154
                     /gene="mapZ"
                     /locus_tag="VW348_000654"
     CDS             29760..31154
                     /gene="mapZ"
                     /locus_tag="VW348_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEU9745596.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTNSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            31230..32654
                     /gene="gndA"
                     /locus_tag="VW348_000655"
     CDS             31230..32654
                     /gene="gndA"
                     /locus_tag="VW348_000655"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEU9745597.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEDQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            32666..33355
                     /locus_tag="VW348_000656"
     CDS             32666..33355
                     /locus_tag="VW348_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9745598.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            33453..34415
                     /gene="cbpC"
                     /locus_tag="VW348_000657"
     CDS             33453..34415
                     /gene="cbpC"
                     /locus_tag="VW348_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEU9745599.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLRSSGAMA
                     TGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMATGWYQDGSTWYYLDPSN
                     GDMKIGWTKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            34434..35432
                     /gene="cbpJ"
                     /locus_tag="VW348_000658"
     CDS             34434..35432
                     /gene="cbpJ"
                     /locus_tag="VW348_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpJ"
                     /protein_id="HEU9745600.1"
                     /translation="MKLLKKTMQAGLTVIFFGLLATNTVFADNSEGWQFVQENGRTYY
                     KKGDLKETYWRVIDGKYYYFDSLSGEMVVGWQYIPFPSKGSTIGPYPNGIRLEGFPKS
                     EWYYFDKNGVLQEFVGWKELEIKTQDSVGRKYGEKRENSEDKEEKRYYTNYYFNQNHS
                     LETGWLYDQSNWYYLAKTEINGENYIGGERRAGWINDASAWYYLDPATGIMQTGWQYL
                     GNKWYYLRSSGAMATGWYQEGTTWYYLDHPNGDMKTGWQNLGNKWYYLRSSGAMATGW
                     YQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(35550..36782)
                     /locus_tag="VW348_000659"
     CDS             complement(35550..36782)
                     /locus_tag="VW348_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9745601.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEIVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTLFLVLSPFSLI
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVMSIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLFALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFVTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(36941..37411)
                     /locus_tag="VW348_000660"
     CDS             complement(36941..37411)
                     /locus_tag="VW348_000660"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745602.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCGIAY
                     ALFAYSKVLEPSMFYNDLHTFHAELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKSNR"
     gene            complement(37311..37649)
                     /locus_tag="VW348_000661"
     CDS             complement(37311..37649)
                     /locus_tag="VW348_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
                     /protein_id="HEU9745603.1"
                     /translation="MTIRTTHTYEYQYSLLFGDAGYLWLLLHLFSISKNQYYLQLANV
                     TAKKLIENYDTLEEIDFALGKSGVLLSLIKYYQFTNDNTLKTFIHNSIWGNLSLFPTK
                     RYSQRKHFRL"
     gene            38312..38590
                     /locus_tag="VW348_000662"
     CDS             38312..38590
                     /locus_tag="VW348_000662"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9745604.1"
                     /translation="MIRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFRRSMTTGWFQVNGRWYYAYSAQVPWQ"
     gene            38765..39643
                     /gene="mvk"
                     /locus_tag="VW348_000663"
     CDS             38765..39643
                     /gene="mvk"
                     /locus_tag="VW348_000663"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEU9745605.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            39625..40578
                     /gene="mvaD"
                     /locus_tag="VW348_000664"
     CDS             39625..40578
                     /gene="mvaD"
                     /locus_tag="VW348_000664"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEU9745606.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGHRYRLIVSKTKDLSQDDCC"
     gene            40565..41572
                     /locus_tag="VW348_000665"
     CDS             40565..41572
                     /locus_tag="VW348_000665"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEU9745607.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAESTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            41556..42566
                     /locus_tag="VW348_000666"
     CDS             41556..42566
                     /locus_tag="VW348_000666"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEU9745608.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            42644..43342
                     /locus_tag="VW348_000667"
     CDS             42644..43342
                     /locus_tag="VW348_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEU9745609.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            43339..44334
                     /locus_tag="VW348_000668"
     CDS             43339..44334
                     /locus_tag="VW348_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9745610.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDQDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            44348..44980
                     /locus_tag="VW348_000669"
     CDS             44348..44980
                     /locus_tag="VW348_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9745611.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            44981..45223
                     /locus_tag="VW348_000670"
     CDS             44981..45223
                     /locus_tag="VW348_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEU9745612.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRSLENTNMWLLTI"
     gene            45148..45459
                     /locus_tag="VW348_000671"
     CDS             45148..45459
                     /locus_tag="VW348_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEU9745613.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLSNLRLT
                     S"
     gene            45484..45750
                     /locus_tag="VW348_000672"
                     /pseudo
     CDS             45484..45750
                     /locus_tag="VW348_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            45900..46139
                     /locus_tag="VW348_000673"
     CDS             45900..46139
                     /locus_tag="VW348_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745614.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            46220..47041
                     /gene="cbpG"
                     /locus_tag="VW348_000674"
     CDS             46220..47041
                     /gene="cbpG"
                     /locus_tag="VW348_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpG"
                     /protein_id="HEU9745615.1"
                     /translation="MNVEGRGSANFIKDNVLITAAHNYYRHDYGKEADDIYVLPAVSP
                     SQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLT
                     GITVTITGYPSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASHRVVG
                     VHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGWKKINGSWYHYRQHDKQTGWQE
                     INDTWYYLDSSGKMLTDWQKVNGKWYYLNSNGAMVTGSQTIDGKVYNFASSGEWI"
     gene            47060..48082
                     /gene="cbpF"
                     /locus_tag="VW348_000675"
                     /pseudo
     CDS             47060..48082
                     /gene="cbpF"
                     /locus_tag="VW348_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpF"
     gene            complement(48210..48823)
                     /locus_tag="VW348_000676"
                     /pseudo
     CDS             complement(48210..48823)
                     /locus_tag="VW348_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT        15229 a         8301 c        10713 g        14580 t
ORIGIN      
        1 tttcctttct gttgataggc tagtagcaga cgattgattt gtctttcaga aagattgagt
       61 tcgacacagg cccgtttctt tgttttcttt ccttgggcta tagcttttat cacaagatat
      121 tttttcgttt cattcatatt cagttggatc cttttcatat gactattcta ccaaatggga
      181 cattttcacg ttcgatttac taaagacatt atcacattcg aattacatta aagatgcaga
      241 tagtaaaaaa aatgtagaca ttaccgtaaa aaagtgatat aatcgtatga tgttcaaggt
      301 ataggtgtta atcatgagta gacgttttaa aaaatcacgt tcacagaaag tgaagcgaag
      361 tgttaatatc gttttgctga ctatttattt attgttagtt tgttttttat tgttcttaat
      421 ctttaagtac aatatccttg cttttagata tcttaaccta gtgataactg cgttagtcct
      481 actagttgcc ttgctagggc tactcttgat tatctataaa aaagctgaaa agtttactat
      541 ttttctgttg gtgttctcta tccttgtcag ctctgtgtcg ctctttgcag tacagcagtt
      601 tgttggactg actaatcgtt taaatgcgac ttctaattac tcagaatatt caatcagtgt
      661 cgctgtttta gcagatagtg atatcgaaaa tgttacgcaa ctgacgagtg tgacagcacc
      721 gactgggact gataatgaaa atattcaaaa actactagct gatattaagt caagtcagaa
      781 taccgatttg acggtcaacc agagttcgtc ttacttggca gtttacaaga gtttgattgc
      841 aggggagact aaggccattg tcctaaatag tgtctttgaa aacatcatcg agtcagagta
      901 tccagactac gcatcgaaga taaaaaagat ttataccaag ggattcacta aaaaagtaga
      961 agctcctaag acgtctaaga atcagtcttt caatatctat gttagtggaa ttgacaccta
     1021 tggtcctatt agttcggtgt cgcgatcaga tgtcaatatc ctgatgactg tcaatcgaga
     1081 taccaagaaa atcctcttga ccacaacgcc acgtgatgcc tatgtaccaa tcgcagatgg
     1141 tggaaataat caaaaagata aattaaccca tgcaggcatt tatggagttg attcgtccat
     1201 tcacacctta gaaaatctct atggagtgga tatcaattac tatgtgcgat tgaacttcac
     1261 ttctttcttg aaaatgattg acttattggg aggggtagat gttcataatg atcaagagtt
     1321 ttcagctcta catgggaagt tccatttccc agtagggaat gtccacctag actctgagca
     1381 ggctctaggt tttgtacgtg aacgctactc actagccgat ggagaccgtg atcgtggtcg
     1441 caaccaacaa aaggtcattg tagcaattat tcagaagtta acttctacag aggttttgaa
     1501 aaactatagt agtattcttc aaggattgca ggattctctt caaacaaata tgccgattga
     1561 gactatgata gatttagtga atactcagtt ggaaagtggg gggaattata aagtaaattc
     1621 tcaagattta aaagggacag gtcggatgga tcttccttct tatgcaatgc cagacagtaa
     1681 cctctatgtg atggaaatag atgatagtag tttagctgta gttaaagcag ctatacagga
     1741 tgtgatggag ggtagatgaa atgatagaca tccattcgca tatcgttttt gatgtagatg
     1801 acggtcccaa gtcaagagag gaaagcaagg ctctcttggc agaatcctac aggcaggggg
     1861 tgcgaaccat tgtctctacc tctcaccgtc gcaagggcat gtttgaaact ccggaagaga
     1921 agatagcaga aaactttctt caggttcggg aaattgcaaa agaagtggca gatgatttag
     1981 tcattgctta tggcgcagag atatactata ctctggatgc tctagaaaag ctagaaaaaa
     2041 aagaaattcc tacccttaat gatagtcgtt atgccttgat tgagtttagc atgcatactt
     2101 cctatcgtca gattcatacg ggattgagca atattttgat gttgggaatc acgccagtaa
     2161 ttgctcatat tgaacgttat gatgctttag agaataacga aaaacgtgtt cgtgaactga
     2221 ttgatatggg gtgctatact cagataaata gttatcatgt ttcaaaacct aagttctttg
     2281 gtgaaaaata taaattcatg aaaaagagag ctcggtattt tttggaacgt gatttagttc
     2341 atgtagttgc aagtgacatg cacaatttag acagtagacc tccatatatg caacaggcat
     2401 atgatatcat tgctaagaaa tatggagcga aaaaagtaaa agaacttttt gtagataatc
     2461 ccagaaaaat tataatggat caattaattt aggagaaaat atgaaggaac aaaacacttt
     2521 ggaaatcgat gtattgcaac tattcagagc tttatggaaa agaaagttgg tcattttatt
     2581 agtggcaatt ataacttctt cagttgcttt tgcctacagt acttttgtta tcaaacctga
     2641 gtttactagt atgactcgga tttatgtagt taaccgtaat cagggagaga agtctggttt
     2701 aaccaatcaa gacttgcagg caggatcatc cttggttaaa gactatcgtg aaattatcct
     2761 atcgcaggat gttttggagg aagttgtttc tgatttgaaa ctagatttga cgccaaaaga
     2821 tttggctaat aaaattaaag taacagtacc agttgatacc cgtattgtct ctgtttcagt
     2881 tagtgatcga gttcctgaag aggcaagccg tatcgctaac tctttgagag aagtagctgc
     2941 tcaaaaaatt atcagtatta ctcgtgtttc tgatgtgaca acactggagg aggcaagacc
     3001 ggcgacatca ccgtcttcgc caaatattaa acgcagtaca ctaattggtt ttttggcagg
     3061 agtgattgga actagtgtta tagttcttat tcttgaactt ttggacactc gtgtgaaacg
     3121 tccgaaagat atcgaagata cactgcatat gacacttttg ggaattgtac caaacttgaa
     3181 taagttgaaa taggagagag gaatgccgac attagaaata gcacaaaaaa aactggagtt
     3241 cgttaagaag gcagaagaat attacaatgc cttgtgtaca aatatacagt tgagcggaga
     3301 taaactaaaa gtaatttccg ttacttctgt taaccctgag gaaggaaaaa caactacttc
     3361 cgtaaatata gcaaggtcgt ttgcgcgtgc aggctataaa actcttttga tcgatggcga
     3421 tactcgaaat tcagttatgt caggattttt taaatctcgt gaaaaaatta cagggctaac
     3481 ggaattttta tctgggacag ctgatttatc tcacggttta tgtgatacaa atattgaaaa
     3541 tttatttgta gttcaatcgg gcactgtatc accaaaccct acagccttgt tacaaagtaa
     3601 aaattttaat gatatgattg aaacattgcg taaatatttt gattatatca ttgttgatac
     3661 agcacctatt ggaattgtta ttgatgcggc aattatcact caaaagtgtg atgcgtccat
     3721 cttggtaaca gcaacaggtg aggtgaataa acgtgatgtc caaaaagcga aacaacaatt
     3781 agaacaaaca gggaaactgt tcctaggagt tgttttgaat aaattagata tctcggttga
     3841 taagtatgga gtttacggtt tctatggaaa ttatggtaaa aaaataattt aggaaagatt
     3901 ctatggatga aaaaggattg aaaatttttt tggcagtatt acagagtatt attgtcattt
     3961 tattggttta ttttcttagc tttgttagag agacagaact tgaacgttct tcgatggtta
     4021 tactatacct tctccacttt tttgtattct attttagttc ctatggtaac aattttttta
     4081 aaagagggta cctagttgag tttaatagta ccataagata tatttttttc tttgcaatag
     4141 ctataagtgt attaaacttt tttatagcgg aacggtttag tatctctaga agaggaatgg
     4201 tatacttctt aactttagaa ggaatatcct tatacttgtt aaatttctta gtaaagaaat
     4261 attggaagca tgtgtttttt aatctaaaaa atagcaagaa aattttactg ttaacagtaa
     4321 cgaaaaatat ggaaaaagtt cttgataaat tgctagaatc tgatgaactt tcatggaaat
     4381 tggtagcagt aagtgttttg gataaatctg attttcaaca tgataaaata cctgtaattg
     4441 aaaaggaaaa aattattgaa tttgcaacgc atgaagttgt ggatgaggtg tttgtcaatc
     4501 ttccaggaga gagctacgat attggagaaa ttatctctag gtttgagaca atggggatag
     4561 atgtaactgt aaatcttaaa gcatttgata agaatttggg tcgcaataaa caaattcatg
     4621 agatggtagg attgaatgta gtcactttct ctacaaattt ttataaaact agtcatgtaa
     4681 ttgctaagcg gattattgat atcatgggtg cattggtagg gctgatacta tgtggtttag
     4741 tcagtattgt attggttcct ttgattcgaa aggatggggg ctctgctatt tttgctcaga
     4801 cgcgtatagg aaaaaatggt cgtcagttca ctttttataa gtttcgctct atgtgtgtag
     4861 atgccgaggc gaaaaaaaga gaactcatgg aacaaaatac catgcagggt ggaatgttta
     4921 aggtggacga tgatcctcgt atcacgaaaa ttggtcgttt tatacggaag actagcttgg
     4981 acgagttacc acagttttat aatgttctaa agggagatat gagtttggtt ggcacacggc
     5041 cacctacagt ggacgagtat gttcagtata cttcagaaca gaaacgtcga ctcagcttta
     5101 aacctggtat tacaggttta tggcaggtta gcggccgtag taaaataacc gattttgacg
     5161 atgttgtaaa attagatgtg gcttatattg ataattggac aatctggaaa gatattgaaa
     5221 ttttgcttaa aactgttaaa gttgtattta tgagagatgg agcgaagtga ggaatgaggg
     5281 atagaatcca acttttaggt gtaacaattg atttgcttac gatgaatgaa acgatagata
     5341 ttgtagaaca atatgtatta gaaaaaagac cactacactt gatgggggtg aatgctgata
     5401 aaattaatca gtgtcataca gatgagaaaa tcaaaaaaat cgttaatgag tcaggaatca
     5461 ttaatgcgga tggagcatca gttgttcttg caagtaagtt tttaggaacg cctgttcctg
     5521 aacgagtagc gggtattgat ttgatgcaat gtcttttaga gttgtcaaat aaaaaaggat
     5581 attcagttta cttttttgga gcaaaagaag aagttttgca agatatgctc aaagtattta
     5641 agagagatta tccaaatttg atagttattg gacacagaaa tggctatttt tctgaagagg
     5701 atgaacaagc tattcaagaa gatattcgtg aaaagaaccc tgattttgtg tttattggaa
     5761 ttacgtctcc taaaaaagaa tatattattc aaaaatttat ggatagtggc gtcaattcgg
     5821 tatttatggg agttggcggt agttttgatg tcttgtctgg tcatatccaa cgagcacctc
     5881 tatggatgca aaagtcaaat ttagagtggt tattccgtgt agctaatgag cctaaacgtc
     5941 tctttaaacg ttattttgta gggaatattt cattcatagg aagagtttta aaagcaaaaa
     6001 gaggtgtaaa atattgaacc agacagagat gattcgctta attcaaaaag ttgaattaga
     6061 tgctataaaa gagtttaaaa aaatctgtga agagaatgat atagattttt tcctccgcgg
     6121 tggtagtgta cttggtgcgg tcaaatacga cggctttatt ccatgggatg atgatatgga
     6181 tatcgctgtc cctcgtgaag catacgacaa acttccaagt gttttcaaag atagaattat
     6241 cgctgggaaa tatcaggttc ttacttatca atactgtgat acgttgcatt gctactttcc
     6301 tcgactattc cttttagaag atgaaagaaa acgtttgggc ttgccacgaa ataccaatct
     6361 aggattgcat ttgattgata tcattccttt agatggagca ccaaatcatt cggttttaag
     6421 aaagatttac tttggcaaag tatactggta tcgtttttta gcaagtttag gaacaactta
     6481 tgttggcgac catgtggata tgcattccac taagcaaaaa ctaattattg gtttctttaa
     6541 aaaactagga tttgcaaaac tatttcctca aaattctgta tacagacgct tggataatct
     6601 ctataaaaag tatgattgga aaaagcagaa gtatgcgggg actatcaatg cttctttatt
     6661 tgctaaagaa gttatgccag tagagatttg gggagaagga gtagagaagc cttttgagga
     6721 tactttcttt aaagttccaa cggagtatga tcgctacctg aaaagacttt acggagaaaa
     6781 ctatctttac gaagagccta gtgatgatga aaagaaatcg catttaggag gacactaatt
     6841 tgttttgtta tattattttg cattacaaag tcttagaaga aactatttct tgtgttaaat
     6901 ctataaaaga aggcaattat aatgcaaagc aaatcgttat tattgataat ttttctaata
     6961 atggtactgg tgaaaaacta caagagcttt atgaatcaga tttagaaatt gatgttttga
     7021 ttaaccatga aaatgctggt tttgctcgtg gaaataatgt ggcttatcaa tttgctaagg
     7081 aaaagtataa ccccgatttc atggttatca tgaataacga tattgagata gaaacagaaa
     7141 attttgaaaa aattgtgaca gatatctatc gtgaggaaaa attccatttg ctcgggccag
     7201 atatcttctc gactacttac caacttcacc aaaacccaaa acggttgaca cattatactt
     7261 atggagaagt taaagctcta aatgaaaaat ttaaaaaagg gagccaagtt agtctagctt
     7321 taaaaatcaa atgttggttg aaagctagta aagttcttcg aacagcaatc tatcaaaata
     7381 gacgtaaaaa aggatcagta gactatagaa aacaggtaga aaacccaatt cttcatggtt
     7441 cttttattgt atattcgaga gattttatcg aaaaagagga gtatgctttt aaccctaaca
     7501 ccttcttcta ctatgaaaca gagatattag attatgaagc tgaattaaaa ggatacaaga
     7561 gaatttatac acctaaaatt agagttttgc accatcaaaa tgttgcaact aatcaagttt
     7621 acacgaactt gttagaaaaa accttgtttt caaataaatg caactttaaa tccaccagtt
     7681 attttttgaa gttgatgaaa gaaaacgagg atgtttaaat gagttattta tttttacttt
     7741 gccttacatt attcttattg actatattct atttctttgc ttttattcaa gatttaattg
     7801 ctcctccagt agttatgtct gtaatgtttc taattagttc agtatttgca ctggttaatt
     7861 caaaaaactg gaatattgaa tatagtggaa tagcctatat tctcataatt agtggtatta
     7921 ttatattttc gcttccttta atggcattaa aatcacctaa ttttaatact gaggttaaga
     7981 ttgctgatcg attaattgat atccaatttt ggaaaattgc tctaactatt ataattgatc
     8041 tctttatttt gtatctttac aggaaggaaa tatataacct tgttcttagt aatggatata
     8101 cggggtcaaa tattcagtgg ttttttagaa atgcaacgag ttatgaaggt gaattgacag
     8161 tgcgaacttt tattcgagtt ctcattcgtg ttattgacgt atctgcttat atttttggat
     8221 atacttttat taataatttt cttatctatc gccataaacg ccctaaagac atattacttt
     8281 tagtaccttt attaatattt atttcaaaaa ctttaatatc aggaggccgg caagatatta
     8341 ttaaaattct gattgcctat gtaatcatga tgtatatcca acaaaaacgg aaagttggat
     8401 ggaatagagt catatctcat aaatatattc accttggatt tgttggttta atagcaggta
     8461 ttccagcatt ttactactct ttgtttttag ccggtcgttc aacgactagg acgctatttg
     8521 agagtgtttc gacctatcta ggaggctcaa ttcagcattt taatcagtat attgaaaatc
     8581 cattagatcc tggtgaagtt tttggcagtg aaacattggt gcctatatta aatatattag
     8641 gggaaatggg cctagttaat tatcgtagta caattcattt agaatttcgg acactaggag
     8701 ttactgtagg aaatgtttat acttttttta gaagaccctt gcatgatttt ggtctagttg
     8761 gtatgtatgt gtttgtcttt gctgtaggtg ctttttttgc tatttattat ttagttctga
     8821 gaaagaaaca ggttggtttt aatttggata ttcataccat tatttattct tatgtctttt
     8881 attggatttt tttatcatca atcgagcaat actcgttcac aatgattagt ctatatacac
     8941 ttgtatttat tgtgttggtt tactttatgg ctatctttta ctggtgtaca gattttaaaa
     9001 gaggaaaact gatttttaaa atttctgact caagtatcaa attaaaagaa gaataacaga
     9061 atgtatagga gagggtagat gaatactaaa attaaaaata taataactag tttttcttat
     9121 gttatttctt caaatctgct catagtttta acctcatcac tagttgtttt gatttttcct
     9181 aaaataatgg gggtaactga gtacagttac tggcaacttt atatttttta tctgacctat
     9241 atcggttttt tccacttggg ttggattgat gggatttatc tcaaatatgg tggcttagaa
     9301 tatacaaatt tagatagaaa acagttttat tctcagatga ttctattttc tagtttctta
     9361 atgctaatct cgctggtatt atttactttg aacctaataa ctgtaaggga tgaaaacgca
     9421 agatatattt ataatatggc tatcattagc atgatagtca caaacttaag aacactctat
     9481 gtttatatct tgcagatgac aaatcgcttg aaggatagtt cagtcattct aattagtgat
     9541 cgcgttttat atgtactcct tttattcatg tttattgtat ttggatggca tgagtacaag
     9601 gtcatgattt gggctgatat tctaggtcga acattttctc tcatgctttc cttctggatt
     9661 tgtaaagata ttgtgtttca gcctttgtca aaatttatct tagatttcaa ggagtccctt
     9721 gataatatcc gtgttggaat caatttaatg ctatctaaca ttgcgagtag catgattata
     9781 ggcattgttc gtatgggaat tcaatggaat tggaatattg aaacattcgg gaaagtgtca
     9841 ttaactttga gtatatctaa tttattaatg acttttatta atgccattgg attagttatc
     9901 tttcctttga taaagcgaac aaagactgag aatttaccta aaatttattc taatttaaga
     9961 aatgctttga tgttggttat gttcgcaatc ttgctcttct actatccttt aaaatttatt
    10021 cttgatattt ggcttcctgc ttataaggat gccttagttt tcatggccct aatttttcct
    10081 atgtcagttt atgaagggaa aatggctttg gtgataaata catatttaaa agcaatgaga
    10141 atggaaaaag acattctcaa aattaatgct ttggttatgt taactagtat ggtagtgaca
    10201 ttagtgacta ctctactact aaataatttg gggctgacag ttgtatctat agttatttta
    10261 cttgctttaa gaagtataat agctgaatta attttatcca aaaaactgaa gatatcagtc
    10321 aagcaagaca ttgctttaga gttacttatg acgattatat ttatttcttc aagttggtat
    10381 ctctctattt ggattgcagt aataatttat ttattggcgt atactttata tttgtattta
    10441 aagcacaaag atatcagaat gtatatagaa tactttaaaa atcataaaaa aatatcataa
    10501 aaattatata tcaatgaaat ggtagattac atttctacct ttttatccat ttaggaggaa
    10561 acgatgaaaa agataatgct agttttcggt acacgtccag aagcaataaa aatgtgttca
    10621 ttagtcaatg agttgagaaa acaggaagat atgaaaacag ttgtttgtgt aactggtcaa
    10681 cacaaggaga tggttagccc tgttttagat ttatttggag ttcaaccaga ctatgattta
    10741 gaaattatga aggctaatca aaacttgttc tctataacaa taagtatttt agaaaaaata
    10801 aaacctgtgt tagaaaaaga acaaccagat attgttttgg ttcacggtga tactactacg
    10861 acatatgcag cagctttagc ggcattttat ctaggaatta aagttggtca tgttgaagct
    10921 ggattacgaa cttacaacct gcaaagtcct ttcccagaag agttcaacag acaatcgact
    10981 tctattattg caaattatca ttttgctcct acagaattag ctaaagaaaa tctaataaaa
    11041 gagggtagaa ataatatcta tgttactgga aatacagtga ttgatgcact tacaactaca
    11101 gtacaaaagg attatacaca ccccgatcta gatttaaacg atggaaatcg cctcatctta
    11161 ttgactgctc atagacgcga aaatctcgga gaacctatga gacatatgtt tagagctgtt
    11221 aaacgagttt taaatgaata tgacgatgtt aaagtaattt atccaattca taaaaatcca
    11281 ttggtacggg aaacagctac agaaattttt ggagatacag aacgtattca gatcattgaa
    11341 cctttagatg ttcttgattt tcacaacttt atgaatcata gttatatgat tctaactgac
    11401 tcaggagggg ttcaagaaga ggcaccttcg ttaggaaagc ctgtattggt catgcgagat
    11461 acgacagaaa gacctgaagg agtagctgct ggaacgttga aattggttgg gactgatgag
    11521 gagactattt atcaaaactt taagatgctt ttagacgatc ccgaagaata taaaaaaatg
    11581 agtcaagcta gtaatcctta tggaaatggt gatgctagta aacagattgt tcgaatttta
    11641 cgtggaattt gagtgtgttc agataaagta atatagaaag gtaccctact atgaaaggta
    11701 ttattctagc aggtggttcg gggacacgtt tatatccttt gactcgcgct gcatcaaaac
    11761 aacttatgcc ggtttatgat aaaccgatga tttactaccc actttcaaca ttgatgttgg
    11821 ctgggattag ggatattttg attatttcca ctccacagga tttacatcga ttccaagagc
    11881 ttcttcaaga cggatctgag tttgggctca aactttctta tgcagagcaa ccaagtccag
    11941 atggtttggc acaagccttt atcattgggg aagagtttat ttctgatgat agcgttgcgc
    12001 tgatcttagg tgacaatatc tatcacggtt ctgggctttc caagatgcta caaaaggcag
    12061 cgagtaagga gtcgggagca actgtttttg gctaccatgt caaggatcca gagcgctttg
    12121 gtgtggttga gtttgatcag gatatgaagg ctatttctat tgaagaaaag ccagagcaac
    12181 ctcgttcaaa ctatgcagtt acaggtctct atttctatga taatgatgta gtagagattg
    12241 ccaagagtat taaaccaagt cctcgtggtg aactggaaat tacagatgta aacaaggctt
    12301 acctagatcg tggtgatttg tctgttgagc ttatgggacg tggctttgct tggctggata
    12361 ctggaactca tgaaagttta ctagaggctt cacagtacat cgaaacagtg caacggatgc
    12421 aaaatgttca ggtagcaaac ttagaagaaa ttgcttaccg tatgggctat atcagtcgag
    12481 aagatgtatt ggccttagcc caaccactta agaaaaatga atacggacag tatctgctcc
    12541 gtttgattgg agaagcatag atgacagata attttttcgg taagacgctt gcggcacgca
    12601 aggttgaagc tattccaggc atgttggagt ttgatatccc cgttcatgga gataaccgtg
    12661 gctggtttaa agaaaatttc caaaaggaaa aaatgcttcc acttggattt ccagagtctt
    12721 tctttgcaga aggaaaattg caaaacaatg tatccttctc acgtaaaaat gtccttcgag
    12781 gtctccacgc agagccttgg gataagtaca tctctgtagc agatggaggg aaagttctgg
    12841 gttcttgggt tgatctacgc gagggtgaaa cctttgggaa tacctatcag acagtgattg
    12901 atgcgagtaa gggaatcttt gttcctcgag gcgtagctaa tggctttcaa gttttatcag
    12961 atacagtgtc atatagctat ctggtcaatg attactgggc tcttgaactc aaacccaagt
    13021 atgcctttgt gaactacgct gatccaagcc ttggtattga atgggaaaat attgcagaag
    13081 cagaggtttc agaagcagac aaacatcatc cactacttaa ggatgtaaaa cctttgaaaa
    13141 aagaagattt ggaataagga aagaatatga ctgaatacaa aaatattatc gtgacaggtg
    13201 gagctggctt tatcggttct aactttgtcc attatgttta cgagaacttt ccagatgttc
    13261 atgtgacagt cctagataag ttgacttatg ctggaaaccg cgcgaatatt gaggaaattt
    13321 taggtaatcg tgttgagtta gttgttggtg acattgctga tgcggagttg gtagacaagt
    13381 tggctgctca agcagatgct atcgttcatt atgcagcgga aagccacaat gataattcgc
    13441 tcaatgatcc atcgccattt attcatacta acttcatcgg aacctatact cttttagaag
    13501 ctgctcgtaa gtatgatatt cgcttccacc atgtatcgac agatgaagtt tatggggatc
    13561 tccctttacg cgaagatttg ccaggtcatg gtgaaggacc aggtgagaaa tttactgctg
    13621 aaacaaaata caacccaagc tctccgtact catcaaccaa ggcagcctca gatttgattg
    13681 tcaaagcctg ggtgcgttct tttggagtca aggcaacgat ttccaactgt tcaaataact
    13741 acggtcctta tcaacatatc gaaaaattca tcccacgtca gattactaac atcctaagtg
    13801 gtatcaagcc aaaactttac ggtgaaggta agaacgttcg tgattggatt cataccaatg
    13861 accattcttc aggagtttgg acaatcttga caaaagggca aatcggtgaa acctacttga
    13921 ttggggctga tggtgagaag aacaataagg aagttttgga acttatcctt aaggaaatgg
    13981 gacaagctgc ggatgcctat gatcatgtga ctgaccgtgc aggacatgac cttcgctatg
    14041 cgattgatgc tagcaagctc cgtgatgagt tggggtggaa acctgaattt accaactttg
    14101 aagctgggct caaggcaaca atcaagtggt atacagataa ccaagaatgg tggaaagcag
    14161 agaaagaagc tgttgaagcc aattatgcta agactcagga gattattaca gtataaaaag
    14221 caggaaatag ctgcttttta ttgctatatt gggaagagtt acatattaga aaggtctaga
    14281 gatgatttta attacagggg caaatggcca attaggaacg gaacttcgct atttattgga
    14341 tgaacgtaat gaagaatacg tggcagtaga tgtggctgag atggacatta ccgatgcaga
    14401 aatggttgag aaagtttttg aagaggtgaa accgacttta gtctaccact gtgcagccta
    14461 caccgctgtt gatgcagcag aggatgaagg aaaagagttg gacttcgcca tcaatgtgac
    14521 ggggacaaaa aatgtcgcaa gagcatctga aaagcatggt gcaactctag tttatatttc
    14581 tacggactat gtctttgacg gtaagaaacc agttggacaa gagtgggaag ttgatgaccg
    14641 accagatcca cagacagaat atggacgcac taagcgtatg ggggaagagt tagttgagaa
    14701 gcatgtgtct aatttctata ttatccgtac tgcctgggta tttggaaatt atggcaaaaa
    14761 cttcgttttt accatgcaaa atcttgcgaa aactcataag actttaacag ttgtaaatga
    14821 ccagtacggt cgtccgactt ggactcgtac cttggctgag ttcatgacct acctagctga
    14881 aaatcgtaag gaatttggtt attatcattt gtcaaatgat gcgacagaag acacaacatg
    14941 gtatgatttt gcagttgaaa ttttgaaaga tacagatgtc gaagtcaagc cagtagattc
    15001 cagtcaattt ccagccaaag ctaaacgtcc gctaaactca acgatgagcc tggccaaagc
    15061 caaagctact ggatttgtta ttccaacttg gcaagatgca ttgcaagaat tttacaaaca
    15121 agaagtgaga taagtagtag aatgattttc tagtctaata aaagaggcag ataatgaact
    15181 ccaaaggagc ttaagatgta cgattatctt gttgttggtg ctggtctctt tggcgcatag
    15241 ctttggctca gtttctatta tcgctcacac catccatcag aagtttaatc tgaaggtacc
    15301 caattatcgc caagaagaag attgggctag gatgggttta ccaatcacac gtaaggaaat
    15361 ctctaattgg catatcaagg caagtcaata ctatttagag tccctttata accttttacg
    15421 agaaaagttg ttagaacaac ctcttcttca tgcggatgaa acctcttatc gggtcttaga
    15481 aagtgatagt cagctgacct actattggac ctttttgtct gggaaagctg agaatcaagt
    15541 aatcacgctt taccaccatg atcagtgtcg gagtggttcg gtagtgcaag aattcctagg
    15601 agattattct ggctatgtgc attgtgatat gttgcggcag taacttagga ctttagtcct
    15661 ctagttctgt ctatgcgata gcagtccaag gtttaggagc aaggcgacgc taagcttggt
    15721 aaactgcgaa ccgctagaag cttatcgtca actggaagaa gctgaacttg ttggatgttg
    15781 ggcgcatgtg agaaggaaat tttttgaagt gccccccaag caagcagata aatcatcctt
    15841 aggagctaaa ggtttagctt attgtgatca gttattttcc ttggaaagag actgggaggc
    15901 tttgccagct gatgaacgac tacagaaacg tcaagaacat ctccaacccc taatggaaga
    15961 cttctttgct tagtgccgtc gtcagtcagt tttatcgggt tcaaaactag gaagggcaat
    16021 tgaatacagc ctcaagtatg aagaaacctt taagaccatt ttaaaagacg gacatctggt
    16081 cctttccaat aatctagctg aacgcgccat taaatcattg gttatgggac ggagtaaaag
    16141 agtccagtgg actcttttag cctaagctaa attttaaaaa gcgagggtgg ttattttctc
    16201 aaagttttga aggagctaaa gcaagagcta ttattatgag cttattggaa acagctaaac
    16261 gtcatcaact aaatagtgag aaatatctat cctatcttct agaatgtctt ccaaacgagg
    16321 aaactctcgt aaacaaagag gttttagagg cctatttacc atggactaaa gttgtacaag
    16381 aaaagtgcaa ataagaaatc tccagattag gaactatccg tgagttcact aatctggaga
    16441 tttttcaata gacctcgtta ttgggcggtt acgatattca tattttttgc aaagatgttg
    16501 tttgaaaaat aattttcaaa aattctgaaa attctgttga catctttctg aaaagagtct
    16561 ataatggaga gaaagtttta aaggagaaaa tgatgaaaag ttcaaaacta cttgcccttg
    16621 cgggcgtgac attattggcg gcgactactt tagctgcatg ctctggatca ggttcaagca
    16681 ctaaaggtga gaagacattc tcatacattt atgagacaga ccctgataac ctcaactatt
    16741 tgacaactgc taaggctgcg acagcaaata ttaccagtaa cgtggttgat ggtttgctag
    16801 aaaatgatcg ctacgggaac tttgtgccgt ctatggctga ggattggtct gtatccaagg
    16861 atggattgac ttacacttat actatccgta aggatgcaaa atggtatact tctgaaggtg
    16921 aagaatacgc ggcagtcaaa gctcaagact ttgtaacagg actaaaatat gctgctgata
    16981 aaaaatcaga tgctctttac cttgttcaag aatcaatcaa aggattggat ggctatgtaa
    17041 aaggggaaat caaagatttc tcacaagtag gaattaaggc tctggatgaa cagacagttc
    17101 agtacacttt gaacaaacca gaaagcttct ggaattctaa gacaacaatg ggagtaatgg
    17161 ctccagttaa tgaagagttt ttgaattcaa aaggggatga ttttgccaaa gctacggatc
    17221 caaatagtct cttgtataac ggtccttatt tgttgaaatc cattgtgacc aaatcttctg
    17281 ttgaatttgc gaaaaatccg aactactggg ataaggacaa tgtgcatatt gacaaagtta
    17341 aattgtcatt ctgggatggt caagatacca gcaaacctgc agaaaacttt aaagatggta
    17401 gccttacagc agctcgtctc tatccaacaa gtgcaagttt cgcagagctt gagaagagta
    17461 tgaaggacaa tattgtctat actcaacaag actctattac gtatttagtt ggtacaaata
    17521 ttgaccgtca gtcctataaa tacacatcta agaccagcga cgaacaaaag gcatcgacta
    17581 aaaaggctct cttaaacaag gatttccgtc aggctattgc ctttggtttt gatcgtacag
    17641 cctatgcctc tcagttgaat ggacaaactg gagcaagcaa aatcttacgt aatatctttg
    17701 ttccaccaac atttgttcaa gcagatggta aaaactttgg cgatatggtc aaagagaaat
    17761 tggttactta tggggatgaa tggaaggatg ttaatcttgc agattctcag gatggtcttt
    17821 acaatccaga aaaagccaag gctgaatttg ctaaagctaa atcagcctta caagcagaag
    17881 gtgtgacttt cccaattcat ttggatatgc cagttgacca gacagcaact acaaaagttc
    17941 agcgcgtcca atctatgaaa caatccttgg aagcaacttt aggagctgat aatgtcatta
    18001 ttgatatcca acaactacaa aaagacgaag taaacaatat tacatatttt gctgaaaatg
    18061 ctgctggcga agactgggat ttatcagata atgtcggttg gggtccagac tttgccgatc
    18121 catcaaccta ccttgatatc atcaaaccat ctgtaggaga aagtactaaa acatatttag
    18181 ggtttgactc aggggaagat aatgtagctg ctaaaaaagt aggtctatat gactacgaaa
    18241 aattggttac tgaggctggt gatgaggcta cagatgttgc taaacgctat gataaatacg
    18301 ctgcagccca agcttggttg acagatagtg ctttgattat tccaactaca tctcgtacag
    18361 ggcgtccaat cttgtctaag atggtaccat ttacaatacc atttgcattg tcaggaaata
    18421 aaggtacaag tgaaccaatc ttatataaat acttggaact tcaagacaag gcagtcactg
    18481 tagatgaata ccaaaaagct caggaaaaat ggatgaaaga aaaagaagag tctaataaaa
    18541 aggctcaaga agatctcgca aaacatgtga aataactgtt gcaaaatata agaaaggatt
    18601 tagtatttct cttgaatgct gaatcctttt ttacatttgt aaagaaagat tctaaatgta
    18661 ctgaccccca aaagttggag cctctttttg tcagaataga gaaaattttt gttaatttta
    18721 cttgtttcct attgctttct cagttattat ttgttatatt aaaagtataa ttatttttat
    18781 ttatcagggt taagcattgc attttcagag gaaggagtat tttttaaaaa ggaaatgtaa
    18841 acgcttgctc aaaaatgaaa ggatttagaa gtttatgaat aaaggattat ttgaaaaacg
    18901 ttgtaaatat agtattcgga aattttcatt aggtgttgct tctgttatga ttggagctgc
    18961 attctttggg acaagtccgg ttcttgcaga tagcgtgcag tctggttcca cggcgaactt
    19021 accagctgat ttagctactg ctcttgcaac agcaaaagag aatgatgggc gtgattttga
    19081 agcgcctaag gtgggagaag accaaggttc tccagaagtt acagatggac ctaagacaga
    19141 agaagaacta ttagcacttg aaaaagaaaa accggctgaa gaaaaaccaa aagaggataa
    19201 acctgcagct gctaaacctg aaacccctaa gacggtaacc cctaagacgg taactcctga
    19261 atggcaaacg gtagagaaaa aagaacaaca gggaacagtc actatccgag aagaaaaagg
    19321 tgtccgctac aaccaactat cctcaactgc tcaaaatgat aacgcaggca aaccagccct
    19381 gtttgaaaag aagggcttga ccgttgatgc caatggaaat gcaactgttg atttaacctt
    19441 caaagaagat tctgaaaagg gcaaatcacg ctttggtgtc ttcttgaaat ttaaagatac
    19501 caataataat gtttttgtcg gttatgacaa ggatggctgg ttctgggaat acaaaactcc
    19561 aggtaatagc acatggtata aaggcaaccg tgttgctgct cctgaaacag gatcaataaa
    19621 ccgtctttct atcactctca agtcagacgg tcagctaaat gccagcaata acgatgtcaa
    19681 tctctttgac acagtgactc taccagctgc ggtcaatgac catcttaaaa atgagaagaa
    19741 gattcttctc aaggcgggct cttatgacga tgagcgaaca gttgttagcg ttaaaacgga
    19801 taaccaagag ggggtaaaaa cagaggatac ccctgctgaa aaagaaacag gtcctgaagt
    19861 tgatgatagc aaggtgactt atgacacgat tcagtctaag gtcctcaaag cagtgattga
    19921 ccaagccttc cctcgtgtca aggaatacac cttgaatgga catactttgc caggacaggt
    19981 gcaacagttc aaccaagtct ttatcaataa ccaccgaatc acccctgaag tcacttataa
    20041 gaaaatcaat gagacaacag cagagtactt gatgaagctt cgcgatgatg ctcacttaat
    20101 caatgcggaa atgacagtac gcttgcaagt tgtggacaat caattgcact ttgatgtgac
    20161 caagattgtc aaccacaatc aagtcactcc aggtcaaaag atcgatgacg aaagaaaact
    20221 actttcttct attagtttcc tcggcaatgc tttagtctct gtttctagtg atcaaactgg
    20281 tgctaagttt gatggggcaa ccatgtcaaa caatacacat gtcagcggag atgatcatat
    20341 cgatgtaacc aatccaatga aggatttggc taagggttac atgtatggat ttgtttctac
    20401 agataagctt gctgctggtg tttggagtaa ctctcaaaac agctatggtg gtggttcgaa
    20461 tgactggact cgtttgacag cttataaaga aacagtcgga aatgccaact atgtaggaat
    20521 ccacagctct gaatggcaat gggaaaaagc ttataagggc attgttttcc cagaatacac
    20581 gaaggaactt ccaagtgcta aggttgttat cactgaagat gccaatgcag acaagaaagt
    20641 tgattggcag gatggtgcca ttgcttatcg tagcattatg aacaaccctc aaggttggga
    20701 aaaagttaag gatatcacag cttaccgtat cgcgatgaac tttggttctc aagcacaaaa
    20761 tccattcctt atgaccttgg atggtatcaa gaaaatcaat ctccacacag atggtcttgg
    20821 gcaaggtgtt ctccttaaag gatatggtag tgaaggtcat gactctggtc acttgaacta
    20881 tgctgatatt ggtaagcgta tcggtggtgt cgaagacttc aagaccctaa ttgagaaggc
    20941 taagaaatat ggagctcatc taggtatcca tgttaacgct tcagaaactt atcctgagtc
    21001 taaatatttc aatgaaaaaa ttctccgtaa gaatccagat ggaagctata gctatggttg
    21061 gaactggcta gatcaaggta tcaacattga tgctgcctat gacctagctc atggtcgttt
    21121 ggcacgttgg gaagatttga agaaaaaact tggtgacggt ctcgacttta tctatgtgga
    21181 cgtttggggt aatggtcaat caggtgataa cggtgcctgg gctacccacg ttcttgctaa
    21241 agaaattaac aaacaaggct ggcgctttgc gatcgagtgg ggccatggtg gtgagtacga
    21301 ctctaccttc catcactggg cagctgactt gacctacggt ggctacacca ataaaggtat
    21361 caacagtgcc atcacccgct ttatccgtaa ccaccaaaaa gatgcttggg taggggacta
    21421 cagaagttat ggtggtgcag ccaactatcc actgctaggt ggctacagca tgaaagactt
    21481 tgaaggctgg caaggaagaa gtgactacaa tggctatgta actaacttat ttgcccatga
    21541 cgtcatgacc aagtacttcc aacacttcac tgtaagtaaa tgggaaaatg gtacaccggt
    21601 gactatgacc gataacggta gcacctataa atggactcca gaaatgcgag tggaattggt
    21661 agatgctaac aataataaag tagttgtaac tcgtaagtca aatgatgtca atagtccaca
    21721 atatcgcaaa cgtacagtaa cgctcaacgg acgtgtcatc caagatggtt cagcttactt
    21781 gactccttgg aactgggatg caaatggtaa gaaactttct actgataagg aaaagatgta
    21841 ctacttcaat acgcaggccg gtgcaacaac ttggaccctt ccaagtgatt gggcaaagag
    21901 caaggtttac ctttacaagc taactgacca aggtaagaca gaagagcaag aactaactgt
    21961 aaaagatggt aaaattaccc tagatcttct agcaaatcaa ccatacgttt tctatcgttc
    22021 gaaacaaacc aatcctgaaa tgtcatggag tgaaggcatg cacatctatg atcaaggatt
    22081 taatagcggt accttgaaac actggaccat ttcaggcgat gcttctaagg cagaaattgt
    22141 caagtctcaa ggggcaaacg atatgcttcg tattcaagga aacaaagaaa aagttagtct
    22201 cactcagaaa ttaactggtt tgaaaccaaa taccaagtat gccgtttatg tcggtgtcga
    22261 taaccgtagt aatgccaagg cgagcatcac tgtaaacact ggtgaaaaag aagtgactac
    22321 ttataccaat aagtctctcg ctctcaacta tgttaaggcc tacgcccaca atacacgtcg
    22381 tgacaatgct acagttgaca atacaagtta cttccaaaac atgtacgcct tctttacaac
    22441 tggatcggac gtatcaaatg ttactcttac tttaagtcgc gaagctggtg atcaagcaac
    22501 ttactttgat gaaattcgta cctttgaaaa caattcaagc atgtacggag aaaaccatga
    22561 tacaggtaaa ggcaccttca aacaagactt tgaaaatgtt gctcagggta tcttcccatt
    22621 cgtagtgggt ggtgtcgaag gtgttgaaga caaccgcact cacttgtctg aaaagcatga
    22681 tccatataca caacgtggtt ggaacggtaa gaaagttgat gatgttatcg atggaaattg
    22741 gtcactcaag accaatggac tggttagccg tcgtaacttg gtttaccaaa ccatcccaca
    22801 aaacttccgc tttgaagctg gtaagaccta ccgtgtaacc tttgaatacg aagcaggttc
    22861 agataatacc tatgcttttg tagtcggtaa gggagaattc cagtcaggtc gtcgtggcac
    22921 tcaagcaagc aacttagaaa tgcatgaatt gccaaatact tggacagatt ccaagaaagc
    22981 caagaaggca accttcctcg tgacaggtgc agaaacagga gatacttggg taggtatcta
    23041 ctcaactgga aatgcaagta atactcgtgg tgattctggt ggaaatgcca acttccgtgg
    23101 ttataacgac ttcatgatgg ataatcttca aatcgaagaa attaccctaa caggtaagat
    23161 gttgacagaa aatgctctga agaactactt gccaacggtt gccatgacta actacaccaa
    23221 agagtctatg gatgctttga aagaggcggt ctttaacctc agtcaggccg atgatgatat
    23281 cagtgtggaa gaagcgcgtg cagagattgc caagattgaa gctttgaaga atgctttggt
    23341 tcagaagaaa acggctttgg tagcagatga ctttgcaagt cttacagctc ctgctcaggc
    23401 tcaagaaggt cttgcaaatg cctttgatgg caatgtgtct agtctatggc atacatcatg
    23461 gggcggagga gatgtaggca agcctgcaac catggtcttg aaagaaccaa ctgaaatcac
    23521 tggacttcgt tatgttccac gtggatcagg ttcaaatggt aacttgcgag atgtgaaact
    23581 tgttgtgaca gatgagtctg gcaaggagca tacctttact gcaactgatt ggccaaataa
    23641 caacaaacca aaagatattg actttggtaa gacaatcaag gctaagaaaa ttgtccttac
    23701 tggtaccaag acatacggag atggtggaga taaataccaa tctgcagcgg aacttatctt
    23761 tactcgtcca caggtagcag aaacacctct tgacttgtca ggctatgaag cagctttggt
    23821 taaggctcag aaattaacag acaaagacaa tcaagaggaa gtagctagcg ttcaggcaag
    23881 catgaaatat gcgacggata accatctctt gacggaaaga atgatggaat actttgcaga
    23941 ttatctcaac caattaaaag attctgctac gaaaccagat gctccaactg tagagaaacc
    24001 tgagtttaaa cttagatctt tagcttccga gcaaggtaag acgccagatt ataagcaaga
    24061 aatagctaga ccagaaacac ctgaacaaat cttgccagca acaggtgaga gtcaatctga
    24121 cacagccctc ttcctagcaa gtgttagcct agccctatct gctctctttg tagtaaaaac
    24181 gaagaaagac tagtatttag taaaacctct taacaagatt acggaagcag tctctatctt
    24241 ttccaatgag gtttatagta cagaaaaagc ctgagaagat atcttctcag gcttttgtta
    24301 agcacataaa tacaatagtg ctatgaaaaa atcacccaga aaaatctgga tgataaatgt
    24361 tatggttgtg ctggttgagg attctgattt tgttgatcag gggttgtatt tgattgttgc
    24421 gtattattgt taggattggt agtcgtacta ttatttgtgc ttggagtggt tgagctagac
    24481 tgtgaagttg aactatctga tgatgagctt gaactttcag ttgatggggg ttgttgtgga
    24541 gcaggtgagc tccacgtaga acgagcacca tttttaaata cgaattctcc atttctgtag
    24601 agcccctctg gtatattcca atcctctgga ttgcttcctt cagacaggta ggtcatcata
    24661 gagcggtaaa ctttggcagc gaccgtaagg ccattgccta caagtggtgt cagacggtta
    24721 gaatagcctg tccatacagc cattgaatat ttacgcgtat agccagcaaa tagttcatca
    24781 ggtgctacaa attgagaggt cttgatgtgg ttttcaattt cctcgtctgt atagttagag
    24841 gttcctgttt taccagcctg agggagccaa gcaagatagg catttcgtcc agttccataa
    24901 ctcaagactg ttttcatcat gtcggtcatc atataggctg tcgtttcctt catggcacga
    24961 gttccgacat tagagaactc tttttcactc ccatcactaa agacgacttt atggatatac
    25021 attggtttat agtaagttcc accatttgca aaggcagcgt aagcagcagc catcttttca
    25081 ctacttgctc catatttttt gtctgattcg gttgtgttac ttgaaatggc atttgagtag
    25141 tgaatacttg ggtagtcgat tccgagacca tttaggaaag tcttggcgcg gttgagtccg
    25201 accttgttta gagtttccac ggctgggacg tttcgcgatt gttgcagggc gtattgcaag
    25261 gtgatgttgc caaagtagcc cctatcccag ttataaacag gggtatttgt cccagggtag
    25321 ttatagggct catcgtgaac gatagtagca gttgaatcgt agacaccgta ctccaaggca
    25381 ggagcatagt ctgtgatcgg tttcatagtt gatccccagt cgcggtttgt ttctactgct
    25441 tggttaattc cgaaggaaac attacttgac tgatggcgtg ctcctagctg ggcaatgact
    25501 ttaccgttag aaacatcaac aatggtagaa gcgacttgca attcatcgtc tggataggca
    25561 acgtattcgt ctgtattgta aatatcccac agatgttttt gagcttcttg gtctacattt
    25621 gtgtagacat ccatcccagt tgtgagcagg ttatagcctg tttcttcttc cacttgattg
    25681 atgacttcct tgaggtaatt atccatgtaa gcagggtaat tacttgctga tttgagactt
    25741 tgtagtccat cagtaattgg tgtattgact gctttctcat actgttcagc agagatgtag
    25801 ccttgatttt tcatttcaga taagaccaag tttcggcggt cttgggctgc ttctggatgt
    25861 gaataggggt catattggtt tggtgcctga ggcattccag ccagcaaggc taactgaggt
    25921 aaacttaaat tattgaggtc tttaccatag tagttttgag ctgctgtctg cattccatag
    25981 ttcccattag acatgtagac cttatttata tagtaggtca agatttcttg cttggttgct
    26041 ttttgttcta actgaatcgc taaccaagct tcctgagcct tacgagaaat agtctggtcg
    26101 gaagtcgaag ttgaaaagta agtcaactta atcaactgtt gggtgagagt tgatccacct
    26161 tggagggaat tgctttgcag attgcgcaag aaagctccca ggatacggat ggtatcaatc
    26221 cccctgtggt cgaagaagcg atggtcttcg atagaaacga ttgccttaac caaatctgtg
    26281 ggaatatcat tagcttgggc attgacgcgg cgttcagaac ccaagtcagc aatgagttga
    26341 tttttattgt cgtagatttt actagaagtt gttgcaacta gtttactctc ggataggcta
    26401 ggagccttgc taacgtagta gaaaaaaact cctccgccta agacaatggc tgcgataacc
    26461 aagcttaaga agctaatgct cagatacttg attaggcgca gaatcgttgg tttgttcatc
    26521 ttgttttacc acctaataaa tgttctttga taacattgag ataaggaatt tgagggaagg
    26581 caccagcctt gatttcatat ccatattctc gaatatattc aagtggcatt gatttttgtc
    26641 ccttatcttg atgatagaag cgaatcaaat cgaatgccgg caataagtag gtttcttgct
    26701 gagaagaaaa gtgaagaagg acaaagcaga ttccttgttg ggcaaggact tgttccatat
    26761 gctgaatctg atgtggatga aaatttttca tcggaatcgc acgtttttgt tttgtttcct
    26821 tgacttcaaa gtcgatgtaa tatccattat aaacgccaga atagtccgtc gttgaagctt
    26881 gtcgaaaata ggcttcaaca atcttggcac gacttcgttg tggatagtcc acttgtacga
    26941 tttgaatagg agttggtttc ttatgtataa cagccaagcc ctgagacaaa tagtagtcgt
    27001 tggtagcatt gatcatcttt tcaaaagaca ttcctcgatt tgcgaaattt ttgggttgag
    27061 aaagagatgt ttgtcttttt tgtgatgaaa ctttatgtgg atagttgacc ataattctcc
    27121 ttattggtac aataacatca ctttattata ccataatttg cacagaaagg gttaaaaatg
    27181 gctacagctt tggttttagg ctattctact tttgatttgg gtttattttc tgataaggat
    27241 cctcgtctta aattgattaa aaaagcgata cgtaaagatt tagaggctat ggcagcagat
    27301 ggggtgtctt ggcttgtgtt tacaggaagt ttgggttttg aatattgggt tttagaggtt
    27361 gctcaggaga tgaaaaccga atacggtttc cagttggcca ccatttttgc ttttgaaacc
    27421 catggggaaa attggaatga aggtaatcag atgaaactga gtcgctttaa gcaggtagac
    27481 tttgtcaaat atgcttatcc tcgctatgaa cacaaggggc agttaagaga ttaccagcag
    27541 tttttgctgg aaaacacgac tagttcctat cttttttatg atgaagaaaa tgaaacaaaa
    27601 ctagcttatt tttaccaaaa gatgaaaaat caagaggact attttataaa gagattaaca
    27661 tttgatcaat taaatgaact tgctgaaaat ttttccgaaa attgaagctt tgaccttgat
    27721 ttttgtttgc ctttttttat ataataatac tagcaagcga gaatggagag agacatggca
    27781 agtattattt tttcagcgaa agatattttt gaacaagagt ttggacgtga agtccgtggc
    27841 tataataaag tagaagttga cgagttttta gacgatgtca tcaaggacta tgaaacctat
    27901 gctgccttgg tcaagtcact tcgtcaggaa attgcggatt tgaaggaaga attaactcgt
    27961 aaaccgaaac cttcaccagt tcaagcagaa ccccttgaag cggcaattac aagttctatg
    28021 acgaattttg atattttgaa acgcctgaat agattggaaa aagaagtttt tggtaaacaa
    28081 attttagata actcagattt ttaagtagtt atttgagatg tgcaattttt ggataatcgc
    28141 gtgaggagaa ttgcttctca tgaggaaagt ccatgctagc acaggctgtg atgcctgtag
    28201 tgtttgtgct aggcgaaacc ataagcctag ggacgagaaa tcgttacggc agttgaaatg
    28261 gctaagtcct tggataggcc agagtaggct tgaaagtgcc acagtgacgg agtctttctg
    28321 gaaacagaga gagtggaacg cggtaaaccc ctcaagctag caacccaaat tttggtcggg
    28381 gcatggagta tgcggaaacg aacgtagtat tctgactgct atcagctaga gctgttagtg
    28441 gtagacagat gattatcgaa ggaagtggtc ctagtcactt ctggaacaaa acatggctta
    28501 tagaaaattg catataggtt ggggctgaga aattttctca acctcatttt ttaaagtgga
    28561 catatagaaa ggtcttgcaa gactgtaaca tgaaaaaaga atttaattta attgcaactg
    28621 tggcagcagg gcttgaggct gtcgttggtc gtgaagtgcg agagttgggc tacgattgtc
    28681 aggttgaaaa tggacgtgtt cgttttcaag gagacgtgag agctattatc gaaaccaacc
    28741 tttggcttcg ggcagcagat cgtatcaaaa ttatcgtagg aacgttccca gctaagactt
    28801 ttgaagagct atttcaggga gttttcgctt tagattggga aaattattta ccacttggag
    28861 ctcggttacc gatttcaaaa gctaaatgtg ttaagtccaa acttcacaat gagcccagtg
    28921 ttcaggctat ttctaagaaa gctgttgtca agaaattgca gaaacactat gctcgcccag
    28981 aaggggttcc tctgatggag aatggcccag agtttaagat tgaggtctct attctcaaag
    29041 atgtggcaac tgtcatgatt gatacgaccg ggtctagcct ctttaaacgt ggttatcgta
    29101 ccgaaaaagg tggcgctcct atcaaggaaa atatggcagc agccatttta caactttcta
    29161 actggtatcc agacaagcct ttgattgatc cgacctgtgg ttcggggact ttctgtattg
    29221 aggcagttat gattgctaga aagatggcgc caggtcttcg tcgctctttt gcatttgatg
    29281 aatggaactg gatcagcgat cgcttgattc aagaagtgcg cacagaagcg gctaaaaaag
    29341 tagaacgtaa gcttgagttg gatatcatgg gctgtgatat tgatgctcgc atggtggaaa
    29401 ttgctaaggc caatgctcag gcagctggtg ttgcaggaga tattactttt aagcagatgc
    29461 gcgtgcagga tttacgttcc gataaaatca atggagtaat catttccaat ccgccttatg
    29521 gtgaacgttt gtcagatgat gcaggagtga ccaagctcta tgctgagatg gggcaagtat
    29581 ttgcaccgct gaaaacttgg agcaaattta tcctgactag tgatgaagct tttgaaagca
    29641 agtatggtag ccaagcagat aagaagcgta agttatacaa cggaaccttg aaagtggatc
    29701 tatatcaata ttttggtcag cgtgtcaaac ggcaagaggt aaaatagaaa gggatactca
    29761 tgagtaaaaa aagacgaaat cgtcataaaa aagaaggtca agaaccgcaa tttgattttg
    29821 atgaagcaaa agagctaaca gttggtcaag ctattcgtaa aaatgaagaa gtggaagcag
    29881 gagtcttgcc tgaggattcc attttggaca agtatgttaa gcaacacaga gatgaaattg
    29941 aggcggataa gtttgcgact cgtcaataca aaaaagagga gttcgttgaa actcagagtc
    30001 tggatgattt aattcaagag atgcgtgagg ctgtagagaa gtcagaagct tcttcggagg
    30061 aagttccatc ttctgaagac atcttactac ccttgcctct ggacgatgag gagcaaggct
    30121 tggatcctct attgctagat gatgaaaatc caacagaaat gactgaagaa gtggaagagg
    30181 agcaaaacct ttctcgtctg gatcaagagg actcagaaaa gaaaagtaaa aaaggcttta
    30241 ttttgaccgt tttggcgctt gtatcagtaa ttatttgtgt cagtgcttat tatgtctatc
    30301 gtcaagtggc tcgttcgacc aaggaaattg aaacttctca atcaactaca gccaatcaat
    30361 cggatgtgga tgattttaat acactttatg acgcctttta cacaaatagc aataaaacgg
    30421 ctttgaaaaa tagccagttt gataaactga gtcaactcaa gactttactt gataagctgg
    30481 aaggtagtcg tgaacatacg cttgccaaat ctaaatatga tagtctagta acgcaaatca
    30541 aggccattca agatgtcaat gcacaatttg aaaaaccagc tattgtggat ggtgtgttgg
    30601 ataccaatgc caaagccaaa tcggatgcta aatttacgga tattaaaact ggaaatacgg
    30661 agcttgataa agtgctagat aaggctatca gtcttggtaa gagccagcaa acaagtactt
    30721 ctagctcaag ttcaagtcaa actagcagct caagttcaag tcaagcaagt tcaaatacga
    30781 ctagtgagcc aaaaccaagt agttcaaatg agactagaag tagtcgcagt gaagtcaata
    30841 tgggtctctc gagtgcaggg gttgctgttc aaagaagtgc cagtcgtgtt gcctataatc
    30901 agtctgctat tgatgatagt aataactctg cctgggattt tgcggatggt gttttggaac
    30961 aaattctagc aacttcacgt tcacgtggct atatcactgg agaccaatat atccttgaac
    31021 gtgtcaatat cgttaacggc aatggttatt acaacctcta taagccagat ggaacctatc
    31081 tctttaccct taactgtaag acaggctact ttgtcggaaa tggcgctggt catgcggatg
    31141 acttggacta ctaagcagtc gttacaaaat tctttctttt caaaagtaaa aatgataaaa
    31201 taaaacaaat gaaacaagag gagtgtcaaa tgacaaaagc taactttggt gtcgtaggta
    31261 tggccgtaat gggtcgtaac cttgccctta atattgaatc acgtggttac acagttgcta
    31321 tctacaaccg tagtaaagaa aaaacggaag atgtgattgc ttgccatcct gaaaagaatt
    31381 ttgtaccaag ctatgacgtt gaaagttttg taaactcaat cgaaaaacct cgtcgtatca
    31441 tgctgatggt tcaagctgga cctggtacag atgctactat ccaagccctt cttccacacc
    31501 ttgacaaagg tgatatcttg attgacggag gaaacacttt ctacaaagat accatccgtc
    31561 gtaatgaaga attggcaaac tcaggtatca actttatcgg tactggagtt tctggtggtg
    31621 aaaaaggtgc ccttgaaggt ccttctatca tgcctggtgg acaaaaagag gcctacgaat
    31681 tggtttcgga tgttcttgaa gaaatctcag ctaaagcacc agaagatggc aaaccatgtg
    31741 tgacttatat cggtcctgat ggagctggtc actatgtgaa aatggttcac aacggtatcg
    31801 agtacggtga tatgcaattg atcgcagaaa gctatgactt gatgcaacac ttgctaggcc
    31861 tttctgcaga ggatatggct gaaatcttta ctgagtggaa caagggtgaa ttggatagct
    31921 acttgatcga aatcacagct gatatcttga gccgtaaaga cgatgaagac caagatggac
    31981 caatcgtaga ctacatcctt gatgctgcag gtaacaaggg aactggtaaa tggacgagcc
    32041 aatcatctct tgaccttggt gtaccattgt cactgattac tgagtcagtg tttgcacgct
    32101 acatttcaac ttacaaagaa gaacgtgtac atgctagcaa ggtgcttcca aaaccagctg
    32161 ccttcaactt tgaaggagac aaggctgaat tgattgaaaa aatccgtcaa gccctttact
    32221 tctcaaaaat catttcatac gcacaaggat ttgctcaatt gcgtgtagcc tctaaagaaa
    32281 acaactggaa cttgccattt gcagatatcg catctatctg gcgtgatggc tgtatcatcc
    32341 gttctcgttt cttgcaaaag attacagatg cttacaaccg cgatgcagat cttgccaacc
    32401 ttcttttgga cgagtacttc ttggatgtta ctgctaagta tcaacaagca gtgcgtgata
    32461 tcgtagctct tgcggttcaa gctggtgtgc cagtgccaac tttctcagca gctattactt
    32521 actttgatag ctaccgttca gctgaccttc cggctaactt gatccaagca caacgtgact
    32581 actttggtgc tcacacttac caacgtaaag acaaagaagg aaccttccac tactcttggt
    32641 atgacgaaaa ataagtaggt cagccatggg gaaacggatt ttattacttg agaaagaacg
    32701 aaatctagct cattttttaa gtttggaact ccagaaagag cagtatcggg ttgatctggt
    32761 agaggagggg caaaaagccc tttccatggc tcttcagaca gactatgatt tgattttatt
    32821 gaacgttaat ctgggagata tgatggctca ggattttgca gaaaaattga gtcgaactaa
    32881 acctgcctca gtcatcatga ttttagatca ttgggaagac ttgcaagaag agctggaagt
    32941 tgttcagcgt tttgcagttt catacatcta taagccagtc tttatcgaaa atctggtagc
    33001 gcgtatttcg gcgatcttcc gaggtcggga cttcattgat caacactgca gtctgatgaa
    33061 agttccaagg acctaccgca atcttaggat agatgttgaa catcacacgg tttatcgtgg
    33121 tgaagagatg attgctctga cccgccgtga gtatgacctt ttggcgacac ttatgggaag
    33181 caagaaagta ttgactcgtg agcaattgtt ggaaagtgtt tggaagtatg aaagtgcgac
    33241 cgagacaaat atcgtagatg tctatatccg ctatctacgg agcaagcttg atgttaaagg
    33301 acaaaaaagc tacattaaaa ccgtgcgtgg tgttggttac accatgcaag aatagaaaag
    33361 cagttgcagt tgtgtaactg cttttttgag gagtttttat atattgacat gcagtcgtgt
    33421 ctttgctaca atcgttttag gaggatatat aaatgaaact tttgaaaaaa atgatgcaag
    33481 ttctactagc agtctttttc tttggtttgc tagctacaaa tacggtattt gcgaatacca
    33541 caggtggccg atttgttgat aaggataata gaaaatatta tgtaaaagat gatcataaag
    33601 caatctattg gcataaaata gacggtaaaa cttactattt tggtgatatt ggagagatgg
    33661 ttgtcggttg gcaatactta gaaattcctg gaacaggtta tcgtgatgat ttatttgata
    33721 atcgtccagt cttcgaaatt ggccttcagg agaagtggta ctattttgga caagatggtg
    33781 ctttgctaga acaaacagat aaacaagtac tagaggcaaa aacgtctgaa aatacaggaa
    33841 aagtatacgg tgaacaatat cctctatctg ctgaaaagag aacttattat tttgataata
    33901 attatgctgt aaagacaggc tggatttatg aagacggcaa ttggtattat ttaaataagc
    33961 taggaaattt tggtgatgat tcttacaatc cactaccaat tggtgaagtt gctaagggtt
    34021 ggactcaaga ttttcatgtt actattgaca ttgatagaag caaacctgct ccatggtact
    34081 acctccgttc ctcaggagca atggccactg gctggtatca ggaaggtacc acttggtatt
    34141 atttagacca gccaaatggc gatatgaaaa caggttggca aaaccttggg aacaaatggt
    34201 actatctccg ttcctcagga gctatggcaa ctggttggta tcaagatggt tcaacttggt
    34261 actatttaga tccttctaat ggagatatga aaataggttg gacaaaagta aatggaaaat
    34321 ggtattatct caattcaaat ggagcaatgg ttacaggtag tcaaactatc gatggtaaag
    34381 tttataactt cgcttcatct ggtgagtgga tttaatgttg gaggatatat aaaatgaagc
    34441 ttttgaaaaa aactatgcaa gctggactaa cagtaatttt ctttggtttg ctagctacga
    34501 atacagtatt tgcagataac tctgaaggat ggcagtttgt ccaagaaaac ggtagaacct
    34561 attacaaaaa gggggacctc aaagaaacct actggcgagt gattgatggt aagtactatt
    34621 attttgattc tctatctgga gagatggttg tcggctggca atatatcccg tttccatcta
    34681 aaggtagtac aattggtcct tacccaaatg gtatcagatt agaaggtttt ccaaagtcag
    34741 agtggtacta ctttgataaa aatggagtgc tacaagagtt tgttggttgg aaagaattag
    34801 agattaaaac tcaagacagt gttggaagaa agtatgggga aaaacgtgaa aattcagaag
    34861 ataaagaaga gaagcgttat tacacgaact attactttaa tcaaaatcat tctttagaga
    34921 caggttggct ttatgatcag tctaactggt attatctagc taaaacagaa attaatggag
    34981 aaaactatat tggtggtgaa agacgtgcag gttggataaa tgatgcttca gcttggtact
    35041 acctagatcc agcaactggt attatgcaaa caggttggca atatctaggt aataagtggt
    35101 actacctccg ttcctcagga gcaatggcca ctggctggta tcaggaaggt accacttggt
    35161 attatttaga ccacccaaat ggcgatatga aaacaggttg gcaaaacctt gggaacaaat
    35221 ggtactatct ccgttcatca ggagctatgg caactggttg gtatcaagat ggttcaactt
    35281 ggtactacct aaatgcaggt aatggagaca tgaagacagg ttggttccag gtcaatggca
    35341 actggtacta tgcttatagc tcaggtgctt tggcagtgaa tacgaccgta gatggctatt
    35401 ctgtcaacta taatggcgaa tgggttcggt aatgacaggg cgcttataat tatattagaa
    35461 cactcgctta atcaaagaag tgactttgtt gtacttgacc tgacgattgg ggagattaaa
    35521 agcatgtgaa atctacacat gctttttcgt tagttatgag tgttgaactt gactaaccat
    35581 tgacaaaaga taagagcaat caaaataaga tacaaaaata tcaatgctaa ctgcaccgaa
    35641 acgcccgatg ctatggatag ggctaatagg gagagcaggg acggggcgag aatgtctact
    35701 gtgctcagag cagagcccac cgtccccatc ttgtcactgg ggatatgggc aaagacagct
    35761 gcttgtaggc gagggctgag aatgccgata atcgtagaac tgatgaaact ggtcacgaaa
    35821 attacgatat aggcttgaca aaggatacta gttattagag ccaataggga aatctcacag
    35881 aaaaccaaga ggtgcgtgaa acggatattt ttaaatagat tactgctggt catattgcca
    35941 aggatagctc cacaagacat gatgatggag agcagggcga agagttgccc aatgctcagt
    36001 tgtgctagtg tctgttggat gaagcggagg gcaatcagcc gaggggacac atccaagatg
    36061 gcaatcatac tggtcgtcag aaacagtagt atgacggtat cttttaacct caggagcaca
    36121 gccagcgact gtttaagatg ttgaaaatat ttcttaaaac tcagtgctgt atgtgacatt
    36181 tcaatccttt tttcaacctc atacaaggta tgtcgaataa catacaggcc caaaaaggca
    36241 atgacaaaag tcagagtgtt gataagggaa atagtttgaa tactcataac attgataagg
    36301 aatgcgccag ctagattggc gacaatgcgg acaaccctca tcagagactg cctgaacccc
    36361 atggcatcat gcaggtcgtc cttaattaca ctgatgtaga gggcgttcat catgtaggca
    36421 gacaggtagc tcaaggtgtc agagatgagg ttgatgatga caatcataat gactgaaatt
    36481 aatgaaaagg gcgacaagac gagaaatagt gtcaaaatag cgtagagcag gattttgatt
    36541 ttggcaatac agagtgcgtg tttgactcta ttttcttgaa aatctcctag aatcccgaga
    36601 aagagttgcg atagtagggg aactatctct gaaatggaaa tcagtaaaat cgctagcgga
    36661 gcgaaattgt actgagccac ataattgata atggcgaggt agaaaatact gtcgccgaat
    36721 gatgaaaaac agctgtttag cagcaactgt ctatatatgt tgtttgtcca aaataatttc
    36781 atacttttct ccttatgtct gcacatcgaa tgggaattta ttatttaata gacaccaata
    36841 taccccctgc ttcctattcc gaagtcaaac aaatctgctt taccactatc tccttgaaac
    36901 atcagtaaac cgtgatcatc tcgttcagaa catgctaaaa ttacctgttg gattttttca
    36961 tcagtaattt gttttgattg tagacagtgg tttgtagtaa gctagttatt ccgtggcaat
    37021 atcctgtcat catttttaga tgatggttaa aaacaaattc ttgatattta ctaataatat
    37081 ctttgtttcc gtcacaatcg tacatacaaa gatataagat tattccggaa attccttcgc
    37141 accaagaaag ttgtaaattt cctaaatttt cagtattaga agtaactttt tctaataatt
    37201 tttttaattc agcatggaat gtatggagat cattatagaa catagaaggt tctaagactt
    37261 tagaataggc aaataaagca tatgcaattc cacaatatcc atgagcaaag ctatagtcta
    37321 aaatgctttc tttggctgta tctctttgta ggaaataatg ataaatttcc ccatatacta
    37381 ttgtggatga aagttttaag agtattgtca ttggtaaatt gatagtattt tattaatgat
    37441 aataggacac cagattttcc caatgcaaag tctatttcct ctagagtatc ataattctct
    37501 attaatttct tagcggtgac gtttgctaat tgtagatagt attgattttt actgatagaa
    37561 aataaatgta ggagtaacca tagatagcct gcatcaccaa atagcagtga gtattgatat
    37621 tcatatgtat gtgtcgttct aattgtcact gccttcttga tgatagagag tattttagaa
    37681 tccagttctg gggggtacaa tttatttaga ggaaacagta gtccagctat tccgtgttgg
    37741 aatgataaat tacttacgaa atttctaaat tctgttgaag aagtgatcct tccttcagaa
    37801 tttacagttt tatctagtaa aaattgtaga acactattac attctgtttt gtaatcatat
    37861 ttatgttcct ctattttttt aattttgact aaattatttg tttgacttaa atttagtaga
    37921 cattgtaacc aaaatagttg ctcatctgtg agctgacctt gagtatgtga tagttctagt
    37981 aattgaatag gatcctttag gtagattcaa tcaatctata acacaacaac ataataacac
    38041 ttttaggata acttatcaaa tattatagta aaatgaaata ataacaggac aaatcgatca
    38101 ggacagtcaa atcgatttct aaaaatgttt tagaagtaga ggtgtactat tctagtttca
    38161 atctactata gtatatattt ttacatcttg aattgtcaaa ttaagtgcat aagtttcccg
    38221 tagcatactt cataaggcgt tttccactta agaaattttc gtggtcgatt atttagaacc
    38281 tgtattcaca aaaaaatgtt aagctagagt tatgatacgc aaagcatatg atactgattt
    38341 aaacgatcaa gaatgggcga agattgaacc ctatttctcc aaacaccgca cctataaatg
    38401 gccgaaacga gtacttgtta atgagacttt gtacgtcact aaaacaggtt gtcaatggcg
    38461 catgctccct cacgactttc ctctttactt aatggtatgg agtttctttc gtcgttctat
    38521 gacgacaggt tggttccagg tcaatggcag atggtactac gcttatagcg ctcaggtgcc
    38581 ttggcagtga atacgaccgt agatggctat tctgtcaact ataatggcga atgggttcaa
    38641 taatgaaaga agcgattgtg aatggaaaca atcgcttttt ttgtgaaaat ataataaaat
    38701 agataggaaa gaattaatac ttgtatgaaa aataagacgt tttttcgtct agtaaaagga
    38761 aaaaatgaca aaaaaagttg gtgtcggtca ggcacatagt aagataattt taatagggga
    38821 acatgcggtc gtttacggtt atcctgccat ttccctgcct cttttggagg tggaggtgac
    38881 ctgtaaggta gttcctgcag agagtccttg gcgcctttat gaggaggata ccttgtccat
    38941 ggcggtttat gcctcactgg agtatttgaa tatcacagaa gcctgcattc gttgtgagat
    39001 tgactcggct atccctgaga aacgggggat gggttcgtca gcggctatca gcatagcggc
    39061 cattcgtgca gtatttgact actatcaggc tgatctgcct catgatgtac tagaaatctt
    39121 ggtcaatcga gctgaaatga ttgcccatat gaatcctagt ggtttggatg ctaagacctg
    39181 tcttagtgac caacctattc gctttatcaa gaacgtagga tttacagaac ttgagatgga
    39241 tttatccgcc tatttggtga ttgccgatac gggtgtttat ggtcatactc gtgaagccat
    39301 ccaagtggtt caaaataagg gcaaggatgc cctaccgttt ttgcatgcct tgggagaatt
    39361 aacccagcaa gcagaagttg cgatttcaca aaaagatgct gaaggactgg gacaaatcct
    39421 cagtcaagcg catttacatt taaaagaaat tggagtcagt agccctgagg cagacttttt
    39481 ggttgaaacg actcttagcc atggtgctct gggtgccaag atgagcggtg gtgggctagg
    39541 aggttgtatc atagccttgg taaccaattt gacacacgca caagaactag cagaaagatt
    39601 agaagagaaa ggagctgttc agacatggat agagagcctg taacagtacg ttcctacgca
    39661 aatattgcta ttatcaaata ttggggaaag aaaaaagaaa aagagatggt gcctgctact
    39721 agcagtattt ctctaacttt ggaaaatatg tatacagaga cgaccttgtc gcctttacca
    39781 gccaatgtaa cagctgacga attttacatc aatggtcagc tacaaaatga ggtcgagcat
    39841 gccaagatga gtaagattat tgaccgttat cgtccagctg gtgagggctt tgtccgtatc
    39901 gatactcaaa acaatatgcc tacggcagcg ggtctgtcct caagttctag tggtttgtcc
    39961 gccctggtca aggcttgtaa tgcttatttc aagcttggat tggatagaag tcagttggca
    40021 caggaagcca aatttgcctc aggttcttct tctcggagtt tttatggacc actaggagcc
    40081 tgggataagg atagtggaga aatttaccct gtagagacag acttgaaact agctatgatt
    40141 atgttggtgc tagaggacaa gaaaaaacca atctctagcc gtgacgggat gaaactttgt
    40201 gtggaaacct cgacgacttt cgacgactgg gttcgtcagt ctgagaagga ctatcaggat
    40261 atgctgattt atctcaagga aaatgatttt gccaagattg gagaattaac ggagaaaaat
    40321 gccctggcta tgcatgctac gacaaagact gctagtccag ccttttctta tctgacggat
    40381 gcctcttatg aggctatgga ctttgttcgc cagcttcgtg agaaaggaga ggcctgctac
    40441 tttaccatgg atgctggtcc caatgttaag gtcttctgtc aggagaaaga cttggagcat
    40501 ttatcagaaa ttttcggtca tcgttatcgc ttgattgtgt caaaaacaaa ggatttgagt
    40561 caagatgatt gctgttaaaa cttgcggaaa actctattgg gcaggtgaat atgctatttt
    40621 agagccaggg cagttagctt tgataaagga tattcccatc tatatgaggg ctgagattgc
    40681 tttttctgac agctaccgta tctattcaga tatgtttgat ttcgcagtgg acttaaggcc
    40741 taatcctgac tatagcttga ttcaagaaac gattgctttg atgggagact tcctcgctgt
    40801 tcgtggtcag aatttaagac ctttttctct agaaatctgt ggcaaaatgg aacgagaagg
    40861 gaaaaagttt ggtctaggtt ctagtggcag cgtcgttgtc ttggttgtca aggctttact
    40921 ggctctgtat gatgtttctg ttgatcagga gctcttgttc aagctgacta gcgctgtctt
    40981 gcttaagcga ggagacaatg gttccatggg cgaccttgcc tgtattgtgg cagaggattt
    41041 ggttctctac cagtcatttg atcgccagaa ggtggctgct tggttagaag aagaaaactt
    41101 ggcgacagtt ctggagcgtg attggggctt ttcaatttca caagtgaaac caactttaga
    41161 atgtgatttc ttagtgggat ggaccaagga agtggctgta tcgagtcaca tggtccagca
    41221 aatcaagcaa aatatcaatc aaaatttttt aagttcctca aaagaaacgg tggtttcttt
    41281 ggtcgaagcc ttggaacagg ggaaagccga aaaagttatc gagcaagtag aagtagccag
    41341 caagctttta gaaggcttga gtacagatat ttacacgcct ttgcttagac agttgaaaga
    41401 agccagtcaa gatttgcagg ccgttgccaa gagtagtggt gctggtggtg gtgactgtgg
    41461 catcgccctg agttttgatg cggaatcaac caaaacctta aaaaatcgtt gggccgatct
    41521 ggggattgag ctcttatatc aagaaaggat aggacatgac gacaaatcgt aaggacgagc
    41581 atatcctcta tgcccttgag cagaaaagtt cctataatag ctttgatgag gtggagctga
    41641 ttcattcttc cttgcctctt tacaatctgg atgaaatcga tctttcgaca gagtttgctg
    41701 gtcgaaagtg ggactttcct ttttatatca atgccatgac tggtggaagt aataagggaa
    41761 gagaaatcaa tcaaaagctg gctcaggtgg cggaatcctg tggtatttta tttgtaacgg
    41821 gttcttatag cgcagccctc aaaaatccaa cggatgattc tttttctgtc aagtctagtc
    41881 atcccaatct cctccttgga accaatattg gattggacaa acctgtcgag ttaggacttc
    41941 agactgtaga agagatgaat cctgttctat tgcaagtgca tgtcaatgtc atgcaggaat
    42001 tactcatgcc cgagggagaa aggaagttta gaagctggca atcgcatcta gcagattata
    42061 gcaagcaaat tcccgttcct attgtcctca aggaagtggg ctttggaatg gatgccaaga
    42121 caatcgaaag agcctatgaa ttcggtgttc gtacagtgga cctatcgggt cgtggtggca
    42181 ccagctttgc ctatatcgaa aaccgtcgta gtggccagcg tgattacctc aatcaatggg
    42241 gtcagtctac catgcaggcc cttctcaatg cccaagaatg gaaagataag gtcgaactct
    42301 tggttagtgg aggggttcgg aatccgctgg atatgattaa gtgcttggtt tttggtgcta
    42361 aggctgtggg attgtcacga accgttctgg aattggttga aacctacaca gttgaagaag
    42421 tgattggcat tgtccaaggc tggaaagcag atctacgctt gattatgtgt tcccttaact
    42481 gtgccaccat agcagatcta caaaaagtag actatcttct ttatggaaaa ttaaaagaag
    42541 caaaggatca gatgaaaaag gcgtaaccag cgcctttttt tccatcctca gactgaggtg
    42601 acttttttga attgtgataa aatagaaggg agaggatgaa cctatgagaa aatttaaaat
    42661 ctttttattt atcgaagcct gtcttctgac aggagctctg attttgatgg tatcagagca
    42721 tttttcgcgt tttctgctga tactattcct ctttttgctt ttgattcgct actacactgg
    42781 taaagaggga aataatcttc ttttagtagc ggcaaccatt ctcttctttt tcatcgttat
    42841 gctcaatcct tttgtgattc tagctatttt tgttgcggtt atctatagcc tctttcttct
    42901 ttacccgatg atgaaccagg aaaaagagca gaccaatttg gtttttgaag aggtcgtgac
    42961 ggttaagaag gagaaaaatc gttggtttgg aaatcttcat catttttcaa gctaccagac
    43021 ttgccaattc gatgatatca atctctttcg cttcatgggt aaggacacta ttcatctgga
    43081 gagggtcatc ttaaccaatc atgacaatgt cattatcctc agaaagatgg taggaacgac
    43141 caaaatcatc gtacctgtag atgtggaagt cagtctcagc gttaactgtc tctatgggga
    43201 tttgactttt ttcaaccagc ccaagcgagc cctccgcaat gaacactatc atcaagaaac
    43261 aaaagactat ctcaagagta acaagagtgt caagattttc ttgaccacta tgattggtga
    43321 tgtggaggtg gttagaggat gaaaaaacaa gcctatgtca ttattgctct cacctccttc
    43381 ctatttgtct tttttttctc ccacagcttg ctggaaatac ttgattttga ctggtctatc
    43441 tttttgcacg atgtcgaaaa aacagaaaaa tttgtctttt tattgttggt tttcagcatg
    43501 tccatgacct gtctcttagc cctgttttgg cgagggatcg aagagctttc tctaagaaaa
    43561 atgcaggcta atctcaagcg tttattggca gggcaagaag tagttcaggt tgtagatcaa
    43621 gatttggatg ccagtttcaa gtccttatca ggtaaactta accttttgac agaggctctt
    43681 caaaaagctg aaaatcatag ccttgctcag gaagaggaaa tcatcgagaa ggaacggaag
    43741 cgaattgctc gggatttgca cgatacagtc agtcaggagt tgtttgcggc ccacatgatt
    43801 ttatcgggta tcagtcagca ggctttgaaa ttggatagag aaaagatgca gacccagttg
    43861 cagagtgtca cagctatttt agaaacagcc cagaaggatt tgcgggtttt gctcttgcat
    43921 ttgcgaccag ttgaactgga gcagaagagc ttgatagaag ggattcaaat tctcttaaaa
    43981 gagcttgagg acaagagtga tcttagggtt agtctcaagc agaatatgac gaaattgcct
    44041 aagaaaatcg aggagcatat cttccgtatc ctgcaagagt tgattagcaa taccctccgc
    44101 catgcccagg catcttgcct agatgtctac ctctatcaga cagatgttga attgcaactg
    44161 aaggtggtgg acaatgggat tggtttccag ttagggagct tagacgactt gagttatgga
    44221 ctgcgaaata tcaaggagcg ggttgaagat atggcaggga cggttcagtt attaacagct
    44281 cccaagcaag ggctggcagt tgatatccgt attcccctgt tagataagga atgataaagg
    44341 agtaaagatg aaaattttac tagtagatga ccatgaaatg gtccgtttgg gtttgaaaag
    44401 ctactttgac ctccaagacg atgtagaagt tgtgggtgag gcgtccaacg ggtctcaagg
    44461 gattgacttg gccttggaac tgcgtccaga tgtcattgtc atggatattg tcatgcctga
    44521 gatgaatggg attgacgcga ccttagcaat ccttaaagaa tggcctgaag ccaagatttt
    44581 gattgtgacc tcttatttgg acaatgaaaa aatcatgcca gtcttagatg ctggtgccaa
    44641 aggctatatg ctcaagactt ctagtgcaga tgaattgctt catgccgtca gtaaggtagc
    44701 tgctggcgag ctggccattg agcaagaggt tagcaagaag gttgaatacc accgcaatca
    44761 tatggaactt catgaagaat tgactgcgcg tgagcgagat gttctccaac tcatcgccaa
    44821 gggctacgaa aatcagcgca tcgcagatga cctctttatc tctctcaaga cggtcaagac
    44881 ccacgtgtcc aatattcttg ccaaacttga agtcagcgat cgtacccagg cggctgtcta
    44941 tgcctttcag caccatttgg tggggcaaga ggagttttag atgagtttag cagatttact
    45001 tgaggagcta gaagcagcaa aagactctaa aaaagcaagg tccatggaag cctatatgcg
    45061 ccatcaattt tcttttctag gtattgcggt gcctgaaaga aataaactct ataaaaatat
    45121 tttccagaag cgaaaaaaac aaagattatc gattgggatt ttgcagacac ttgctgggaa
    45181 aaggagccta gaaaatacca atatgtggct gctaactatt tgaaagcaat gcagtcttat
    45241 ctaaaggaaa ccgatttgcc taagctagag cagttagtcg tgacaaaatc ctggtgggac
    45301 acggtagata tcctagatcg agtagtaggg agtttggtgt atgaacaccc tgaactagaa
    45361 gaaataatct taatactctt cgaaaatctc ttcaaaccac gtcagctcta tctgcaacct
    45421 caaaacagtg ttttgagcaa tctgcggcta acttcctagt ttgctctttg attttcattg
    45481 agtataaaat ggagcctatc agataatatc tggctgagac gtgtcgctat tgaccaccag
    45541 ttgttaagaa aagagaagac caatactcaa ttaatggaaa agattctact tcataacttg
    45601 aaccaaacag aattttttat caataaagcc attggctgga ttctgcgaaa ctactccaaa
    45661 acgaatccaa cttgggtaac atgctttatt gatgaaaaca aggaaagaat ggctgaactt
    45721 agtatcaaag aagcaagcaa gtacctctag cgtgattgaa aagcgcagtc attaattgaa
    45781 aagtttacct gtttatgtga taatggaggg tatttaaaga aggtggtaga tttcttgatt
    45841 ctatagtaga ttaagaaatt tagaatagta ggctataatt acattaggag gctacaataa
    45901 tgaagaaaac tgtttataaa aaattgggta tttcaattat tgcgagtact ttattggcta
    45961 gccagttatc gacagtatct gctttgagtg ttatttctag tacgggtgaa gaatatgagg
    46021 taagtgagac actagaaaaa ggtccaggat ctaatgattc ttcattatct gagatttcac
    46081 caacgtatgg ttcatactac caaaagcaat cagaagtatt atcggtaatg atgatttgat
    46141 taaaattgat aatactttac agtatccgta ttcgacttca gctatggttt tatctaagta
    46201 ttatggagta gccgatggaa tgaatgtaga agggagggga agtgcgaatt ttattaaaga
    46261 taatgtgtta attacagcgg ctcacaacta ctacagacat gactatggga aagaagcgga
    46321 tgatatttat gttcttccgg ctgttagtcc aagtcaagaa ctatttggaa agatcaaagt
    46381 aaaggaagtt cgttatttga aggaatttag aaatttaaat tctaaggatg caagggaata
    46441 tgacttggct ttattaattc tagaagagcc cattggtgca aaattaggga ctttgggtct
    46501 tcctactagt caaaaaaatt tgacaggaat aactgtgact atcacaggct atccatcata
    46561 taattttaaa attcatcaaa tgtatacaga taaaaaacaa gttttaagtg atgatggcat
    46621 gttcttggat taccaagttg atactttaga ggggtctagt ggatctacag tttatgatgc
    46681 tagtcaccgt gtagtaggag tgcatacttt aggagatgga gctaatcaaa ttaacagtgc
    46741 agttaaatta aatgaacgaa atttgccatt tatttattcg gttcttaaag gttactctct
    46801 tgaaggatgg aagaaaataa atggtagttg gtaccattat agacaacatg ataaacaaac
    46861 gggttggcag gagataaatg atacttggta ttatttagac agttccggta agatgcttac
    46921 agattggcaa aaagtaaatg gaaaatggta ttatctcaat tcaaatggag caatggttac
    46981 aggtagccaa actatcgatg gtaaagttta taacttcgct tcatctggtg agtggattta
    47041 atgttggagg atatataaaa tgaagctttt gaaaaaaatg atgcaagtcg cactagccac
    47101 atttttcttc ggtttgctag ggaccagtac agtatttgca gatgattctg aaggatggca
    47161 gtttgtccaa gaaaatggta gaacctacta caaaaagggg gatctaaaag aaacctactg
    47221 gagagtgata gatgggaagt actattattt tgatccttta tccggagaga tggttgtcgg
    47281 ctggcaatat atacctgctc cacacaaggg ggttacgatt ggtccttctc caagaataga
    47341 gatttctctt agaccagatt ggttttattt tggtcaagat ggtgtattac aagaatttgt
    47401 tggcaagcaa gttttagaag caaaaactgc tacgaatacc aacaaacatc atggggaaga
    47461 atatgatagc ccagcagaga aatgagtcta ttattttgaa gatcagcgta gttatcatac
    47521 tttaaaaact ggttggattt acgaagaggg tcattggtat tatttacaga aggatggtgg
    47581 ctttgattcg cgcatcaaca gattggcggt tggagagcta gcacgtggtt gggttaagga
    47641 ttcccctctt acctatgatg aagagaagct aaaagcagct ccatggtact atctagatcc
    47701 aacaactggc attatgcaaa ctggttggca atttctaggt aatagatggt actacctcca
    47761 ttcgtcagga gctatggcaa ctggctggta taaggaaggc tcaacttggt actatctaga
    47821 tgctgaaaat ggtgatatga gaactggctg gcaatacctt ggtaacaagt ggtactatct
    47881 ccgttcatca ggagctatgg caactggttg gtatcaggaa ggttcgactt ggtactatct
    47941 aaatgcaagt aatggagata tgaaaacagg ctggttccaa gtcaatggta actggtacta
    48001 tgcctatgat tcaggtgctt tagctgttaa taccacagta ggtggttact acttaaacta
    48061 taatggtgaa tgggttaagt aatgaaggct aattgtaaac tgtgatggat acttaacttt
    48121 gtataatagg tggataaaag tcttcacaat caaaaaacgc atagtatcaa ggtttttctg
    48181 tactgccccc caaaagttag acaaataatt tatccaaagg atttagttct gtactgcaca
    48241 ggactaagtc cttttagttt taccttaatt ctcttgttgt tgtaataatc aatatagtct
    48301 ataatagctt gttccaattg attaagtgat ttaaatgttt tctcatagcc ataaaacatt
    48361 tccgatttca gaatcccaaa gaaggactcc accatagtgc ttctctgtga atgcctgttc
    48421 caacattgtt tgtacttgtt ctaagttggg tgaagttgaa agattatagg cgataatttc
    48481 actgttaaag ccatctaaaa ctggtgataa gtaaagcttt tgagtacttg ctggaatggc
    48541 aaattctgtc acatctgtgt agcacttttc cattgtttta gagccttcaa attggccttg
    48601 aatgagattc tctgccttct taccaacgtc tcctttattt tcgtttctgt cgcattttag
    48661 cttgtaaatt gagtactttc atcaagcctt gaactctttt atgatttacc agataaccac
    48721 gatttcttag ttctaaatga acccggcgat aagtataatt tcccttgtgt tcgataaaaa
    48781 tggattgaat ttcagcttta agctcttggt ccttatctgg ttt
//
LOCUS       DAVKMJ010000012        47519 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000012 DAVKMJ010000000
VERSION     DAVKMJ010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47519
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.012"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(77..373)
                     /locus_tag="VW348_000677"
     CDS             complement(77..373)
                     /locus_tag="VW348_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745616.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(357..2516)
                     /gene="pfbA"
                     /locus_tag="VW348_000678"
     CDS             complement(357..2516)
                     /gene="pfbA"
                     /locus_tag="VW348_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEU9745617.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYSGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVVN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKINNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3646..4872)
                     /locus_tag="VW348_000679"
     CDS             complement(3646..4872)
                     /locus_tag="VW348_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEU9745618.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFKNEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4915..5607)
                     /locus_tag="VW348_000680"
     CDS             complement(4915..5607)
                     /locus_tag="VW348_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEU9745619.1"
                     /translation="MLKWEDLPVEMKSSEVESYYHLVSKRKGSLIFKRCLDWFLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(5780..7531)
                     /locus_tag="VW348_000681"
     CDS             complement(5780..7531)
                     /locus_tag="VW348_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9745620.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDDQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLTLGG
                     TYHKMYSLQAGAMADTL"
     gene            complement(7521..9266)
                     /locus_tag="VW348_000682"
     CDS             complement(7521..9266)
                     /locus_tag="VW348_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9745621.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLVFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGTHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9394..9924)
                     /locus_tag="VW348_000683"
     CDS             complement(9394..9924)
                     /locus_tag="VW348_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEU9745622.1"
                     /translation="MTLNYIEILIKLVLTLKWLNNNVHFVKRLIDGKPTLLIKNGNID
                     PEACRSVGLSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKYPVVTDG
                     VIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYEKEKPGVLYSS
                     KISSNRVNVALPYVGY"
     gene            complement(9921..10377)
                     /locus_tag="VW348_000684"
                     /pseudo
     CDS             complement(9921..10377)
                     /locus_tag="VW348_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10511..11338
                     /gene="xth"
                     /locus_tag="VW348_000685"
     CDS             10511..11338
                     /gene="xth"
                     /locus_tag="VW348_000685"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEU9745623.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11350..11448
                     /locus_tag="VW348_000686"
     CDS             11350..11448
                     /locus_tag="VW348_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU9745624.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEY"
     gene            11493..11732
                     /locus_tag="VW348_000687"
     CDS             11493..11732
                     /locus_tag="VW348_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEU9745625.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRLLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      12115..12210
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12610..13191
                     /locus_tag="VW348_000688"
     CDS             12610..13191
                     /locus_tag="VW348_000688"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEU9745626.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13191..14453
                     /locus_tag="VW348_000689"
     CDS             13191..14453
                     /locus_tag="VW348_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEU9745627.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14503..14964)
                     /locus_tag="VW348_000690"
     CDS             complement(14503..14964)
                     /locus_tag="VW348_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DpnD"
                     /protein_id="HEU9745628.1"
                     /translation="MKTKQLVASEEVYDFLKVIWPDYETESRYDNLSLIVCTLSDPDC
                     VRWLSENMKFGDEKQLALMKEKYGWEVGDKLPEWLHSSYHRLLLIGELLESNLKLKKY
                     TVEITETLSRLVSIEAENPDEAERLVREKYKSCEIVLDADDFQDYDTSIYE"
     gene            complement(14961..15725)
                     /locus_tag="VW348_000691"
     CDS             complement(14961..15725)
                     /locus_tag="VW348_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEU9745629.1"
                     /translation="MELHFNLELVETYKSNSQKARILTEDWVYRQSYYPNCGNNPLNH
                     FENNRPVADFYCNHCSEEFELKSKKGNFSSTINDGAYATMMKRVQADNNPNFFFLTYT
                     KNFEVNNFLVLPKQFVTPKSIIQRKPLAPTARRAGWIGCNIDLSQVPSKGRIFLVQDG
                     QVRDPEKVTKEFKQGLFLRKSSLSSRGWTIEILNCIDKIEGSEFTLEDMYRFESDLKN
                     IFVKNNHIKEKIRQQLQILRDKEIIEFKGRGKYRKL"
     gene            complement(15906..16310)
                     /locus_tag="VW348_000692"
     CDS             complement(15906..16310)
                     /locus_tag="VW348_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEU9745630.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVIGQRSEERRVRI"
     gene            complement(16380..17861)
                     /locus_tag="VW348_000693"
     CDS             complement(16380..17861)
                     /locus_tag="VW348_000693"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU9745631.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWETYVHYPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIVAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVDQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKAFRFAGFEQVKAGIVKWPMSVLRLTSDSKEDLINLADKILQEWRQYSDPAVQ
                     ILAETDRTPHHTITPIARKRDGQFELDLVLRDNQTSAEYPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            complement(17880..19058)
                     /locus_tag="VW348_000694"
     CDS             complement(17880..19058)
                     /locus_tag="VW348_000694"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEU9745632.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKETVGKHYEEVVGYAPSFYIAEVAGGTHVLD
                     "
     gene            19223..20230
                     /gene="galR"
                     /locus_tag="VW348_000695"
     CDS             19223..20230
                     /gene="galR"
                     /locus_tag="VW348_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEU9745633.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(20276..21313)
                     /locus_tag="VW348_000696"
     CDS             complement(20276..21313)
                     /locus_tag="VW348_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU9745634.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(21314..21667)
                     /locus_tag="VW348_000697"
     CDS             complement(21314..21667)
                     /locus_tag="VW348_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU9745635.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(21911..22801)
                     /locus_tag="VW348_000698"
     CDS             complement(21911..22801)
                     /locus_tag="VW348_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEU9745636.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            22934..23470
                     /locus_tag="VW348_000699"
     CDS             22934..23470
                     /locus_tag="VW348_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU9745637.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFQKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FIGQEVVQFYLDLLIPKN"
     gene            complement(23636..24442)
                     /locus_tag="VW348_000700"
     CDS             complement(23636..24442)
                     /locus_tag="VW348_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEU9745638.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(24787..26307)
                     /locus_tag="VW348_000701"
     CDS             complement(24787..26307)
                     /locus_tag="VW348_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEU9745639.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDSIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(26300..27028)
                     /locus_tag="VW348_000702"
     CDS             complement(26300..27028)
                     /locus_tag="VW348_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9745640.1"
                     /translation="MIEYKNVALCYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(27042..27806)
                     /locus_tag="VW348_000703"
     CDS             complement(27042..27806)
                     /locus_tag="VW348_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEU9745641.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGATYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLKNGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(27810..28253)
                     /locus_tag="VW348_000704"
     CDS             complement(27810..28253)
                     /locus_tag="VW348_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU9745642.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(28935..29231)
                     /locus_tag="VW348_000705"
     CDS             complement(28935..29231)
                     /locus_tag="VW348_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU9745643.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(29253..30317)
                     /gene="pepA"
                     /locus_tag="VW348_000706"
     CDS             complement(29253..30317)
                     /gene="pepA"
                     /locus_tag="VW348_000706"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEU9745644.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALLGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            30718..31419
                     /gene="galE"
                     /locus_tag="VW348_000707"
     CDS             30718..31419
                     /gene="galE"
                     /locus_tag="VW348_000707"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU9745645.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMDQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQHDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            31842..32801
                     /locus_tag="VW348_000708"
     CDS             31842..32801
                     /locus_tag="VW348_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9745646.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFISSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            32791..33747
                     /locus_tag="VW348_000709"
     CDS             32791..33747
                     /locus_tag="VW348_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEU9745647.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            33744..34496
                     /locus_tag="VW348_000710"
     CDS             33744..34496
                     /locus_tag="VW348_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9745648.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            34592..35557
                     /locus_tag="VW348_000711"
     CDS             34592..35557
                     /locus_tag="VW348_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9745649.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETSTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(35782..36024)
                     /gene="yidD"
                     /locus_tag="VW348_000712"
     CDS             complement(35782..36024)
                     /gene="yidD"
                     /locus_tag="VW348_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEU9745650.1"
                     /translation="MKRILIALVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(36024..36746)
                     /locus_tag="VW348_000713"
     CDS             complement(36024..36746)
                     /locus_tag="VW348_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEU9745651.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(36733..37302)
                     /locus_tag="VW348_000714"
     CDS             complement(36733..37302)
                     /locus_tag="VW348_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEU9745652.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQALDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(37321..38049)
                     /locus_tag="VW348_000715"
     CDS             complement(37321..38049)
                     /locus_tag="VW348_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEU9745653.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(38049..38789)
                     /gene="xerD"
                     /locus_tag="VW348_000716"
     CDS             complement(38049..38789)
                     /gene="xerD"
                     /locus_tag="VW348_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEU9745654.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQRRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(38780..39241)
                     /locus_tag="VW348_000717"
     CDS             complement(38780..39241)
                     /locus_tag="VW348_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU9745655.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(39238..39759)
                     /locus_tag="VW348_000718"
     CDS             complement(39238..39759)
                     /locus_tag="VW348_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEU9745656.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(39735..40706)
                     /locus_tag="VW348_000719"
     CDS             complement(39735..40706)
                     /locus_tag="VW348_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEU9745657.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(40703..41497)
                     /gene="racE"
                     /locus_tag="VW348_000720"
     CDS             complement(40703..41497)
                     /gene="racE"
                     /locus_tag="VW348_000720"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEU9745658.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(41704..41952)
                     /locus_tag="VW348_000721"
     CDS             complement(41704..41952)
                     /locus_tag="VW348_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEU9745659.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(42208..43833)
                     /gene="treC"
                     /locus_tag="VW348_000722"
     CDS             complement(42208..43833)
                     /gene="treC"
                     /locus_tag="VW348_000722"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEU9745660.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWTPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGIKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQTLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(44011..45978)
                     /gene="treP"
                     /locus_tag="VW348_000723"
     CDS             complement(44011..45978)
                     /gene="treP"
                     /locus_tag="VW348_000723"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEU9745661.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFVYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            46163..46873
                     /gene="treR"
                     /locus_tag="VW348_000724"
     CDS             46163..46873
                     /gene="treR"
                     /locus_tag="VW348_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEU9745662.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            47028..>47519
                     /locus_tag="VW348_000725"
     CDS             47028..>47519
                     /locus_tag="VW348_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9745663.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIIKKDTHKEIIAKLDYEAPSCP
                     ECGSQMKKYYFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKIMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFECNFRNLPKIMSWDVET
                     VRGV"
BASE COUNT        13928 a        10783 c         8890 g        13918 t
ORIGIN      
        1 aactagaata gtacacctct acttctaaaa cattgttaga aatcgatttg actgtcctga
       61 ttgatttgtc ctattattat ttcattttac tatactctgt taattcatat gagtttaaac
      121 cgatttcatc tttaacctcg agtaaagcag tttcaaatat ttgtttaaga gtttttgatt
      181 ctttacaatt aaccgacaaa ctttctgata aaatatgtac aacttctgag actgaataac
      241 ctatctcctc tttagaatta tataaatctg tagctccacc aataatccaa aaatactgat
      301 tttgtgaacc tacaatatcc tcattttcta cggaacttcc ttgtatcgaa caaattttat
      361 ttatctttac cataatactt caaccctttt agtgtcaaaa gtaaaccaat tcctgtcact
      421 gttaagaata gttccataat cttgttcgaa ccagtctttg gtaatttttg ttttacatct
      481 actatttctt tagatttatt aatatgattt tcagtttctc tgccatctcc aactatttta
      541 tagtttactt cttctgtctt attatcttgt ttattgttga tcttgtcatt catttgtcta
      601 ttatctttac ttgagttaaa ctctccgttc ttctggttac tatcaattac attatttgaa
      661 ttagattgtt tttcctcttt gtttttttct ttttcgtttt tatcacttaa attatttgtt
      721 acaattttgt aaagcccatt ctccgttaca atattgaaat taccatcgct atcacgtata
      781 acaggttctt tcccatttgc attagatttg atgaatgata tatacttacc ggataaatta
      841 taaaattggt tatttaaaac ggttatttta ccctttgaat cctcaataac aattccttct
      901 ttaccaccga atatactatt ctctgagact actaaattat cactaactcg taataattca
      961 atatttggtt gttctgtttc cttagaatta ttattaacta cattttttgt tacagtaata
     1021 tctgatactt ttcctaaata ttctgcacta tcttttgcaa ctcgtatcgc ttttgtttta
     1081 ggatcggcaa tattaaatat attttcggcg ataaccacct gtttatttaa atctaatagg
     1141 tctttagtgt ttttatagct ataagcattt actaaagctg ctccgctttc tcgataatgt
     1201 acactctctc ctttaacttt cttatcaaag cgatttcctt tgattaatac atcagtgaat
     1261 cctgtaaaac gtacacctga atacatcatg ttatcaaaat gattatttaa aattttaata
     1321 ttagaggggt tctgtgtcga caatgtttga tagtgtgtgc caattgctgt tactaattcc
     1381 ccagatttat cacttttgcc aaaataggaa ttttgaatag tcacattttc agattttttc
     1441 ccatcatcat tcaaggcata aggaaaacct tttctagtta atggttcaat ctgaatgctc
     1501 tccttactta tgatttgccc atccttcatc gttttgggta aggcttgccc aagaaaacga
     1561 gaattatcaa ctaatacatt tttcgaacct gcaatttgaa tagcatgccc ttgataacta
     1621 tccttgaatg ttacattttt tatagttacg ttatttgaat tcccaatagc aaatgcacct
     1681 gaagaattta taagtggtag attttttgct ttagttcctt cttcattcaa agcaccgttc
     1741 atatcaatcg taccaccaga ataactaata tcttctgttg ggccccattc tacttgcgca
     1801 ccatcatccg taaataaacc tgtcataaaa acaatggaag ggtgattctt aatatttata
     1861 ccatttagaa ttgtagcttt ctcattcaat tctaagtgtg tatgactttt taaaaaaaca
     1921 atttctttta ctaaataagt tccttcagga aaatatacat ttcctccacc tagcccttga
     1981 gctgcagcat ctattgcatc ttgaattgct tgtcgatcat catgaatccc atcacctacc
     2041 gcaccataat cttttacact taaagcagta tcttcaaatt cttttttgat aattctgtca
     2101 cttataacat cttccttata actcttattt tcattagtag atgttactgt agattcaact
     2161 gttctgttgt ctaattgtga attggaacga atagtaccat tagagctgat actattaaca
     2221 cttaacgaat tatctaaacc attagtggtt gaattagagg caatcatttc agcagaacga
     2281 ttctgattaa cagttggtga attatctaaa tcattagtaa ttgcattaga agactctttt
     2341 gtagccatcg gtgaagaact agtaacaact tcatccgata aaataccttg gcttcccaaa
     2401 attgaaattg ccaatagtac cgagcaagtc cctaccttta atttacgaat actgaatacc
     2461 tcattaggaa caaaatattt catcagaacc tccaattttt ttactatttt taacaattga
     2521 ttattacttt tcttaaaata gatagaatga caccgctgtc attatcttta tcatatattt
     2581 tccaaattga attgtcaagg aataacacaa gaaaatatta aaatttatac tcttcggaaa
     2641 tctcttcaaa ctaggtcagt gccgccttgc cctaagtcta ggttactgac ttggtcagtt
     2701 ctatagtaga cggaaactat aatagtacac ctctacttct aaaacattgt tagaaatcga
     2761 tttgactgtc ccgatcgatt tgtcctattc ttatttcatt ttactatatc tacaacctca
     2821 aagcagggtt ttgagctatc tatggccaac ttcctagttt gctctttagc cttccattca
     2881 aaagtgatgc tatctttctt agcttgaata taaaatatcc catttactat atttaaattt
     2941 gttgatatgt tgtaaattat aaatgaaaga acaaatacct tgtcatacaa gcattcgcca
     3001 gggatattta catgaatatc gctcatatgg cggattgaaa ctaaaacact acaatatatt
     3061 tcttaaatag accttctata aaagctagat ttaacctcga taaaaataga tgcagtgctt
     3121 ctaaaatact ggaatagggc atataggtaa tcgtagacaa gtgttttata gattgtctcg
     3181 cgggagatct aatgatgtat agcaagcatc actaaacata tagaatattt gtattattat
     3241 aagatcaata tgctataaat tctatcatgc aaaagaatga ctagaacatg aaagacaggc
     3301 acaaaacttt gaacaatatt ctgaaaacaa aaaaagacgc gagtttccac aatctcactc
     3361 atggaaactc acgtctttca aaaaataggg tgaattgaaa actagaacaa gacactagat
     3421 tttctaaatg atgtctagta aggattctaa atgctacacc aaattgctca catcttattt
     3481 caaaccacgg gactctcaca agaaaggaaa atcctataaa aattctctct ctgaggagaa
     3541 agaggcctca actacaggtg taaactatta tcaattgaaa acaacagttt ttacactcaa
     3601 ttagactttt tagggacagg atcactttcg cttgactgta gtttgtcatt tttttgataa
     3661 agttagcact ttttcagaaa ctgttttgaa agtctcaatg atatagtcta cttcttcatc
     3721 gcttaattta gtatgaagag ggagggtaat ttcattctta aagaaggcat aggccttagg
     3781 atagttcgtc atatcaaatc caagattctt ataggctgtc aagagaggaa gcggtttgta
     3841 gtgaacatta cttgcaattc ctgctttagc caattcttgg atgatgaggt tgcgttcttc
     3901 taggcttgct ccttctacac gggtgatgta gaggtggcgt gaagattcga cagtttcagt
     3961 cttgtgtgcc aaaggatgga tgcgagaacc tgcaaaacca ctatcatagc ggtccacaat
     4021 gtccttacgg cgttgcaaca aacttggata gcggtccaat tgtaccaaac caagtgaagc
     4081 catgatatcg gtcatgttgc acttataggc tggtgtaacg atatcgtatt cccatgaccc
     4141 cagttgcatc ttggcaagag catccttagt ttgcccgtga agggaaagga tttggaattc
     4201 cttgtacatc tcttcgtcat caatcactgg attggctttc caagtcgcac ttccaccttc
     4261 tgccgttgta aagttcttaa cggcatggaa tgagaaggaa gtaaagtcag cgatagaacc
     4321 agaaggttgt cctttataag tagatcccaa agcgtgggca ctatcagaga caatgacaat
     4381 acggttaaag gccttttgcc acttgcttga agcagtaaag aagtcacgtt ttttctccac
     4441 gacttggaac aaacggtcat aatcgcaaac aatccctgcg agctctactg ggataatcac
     4501 cttagttttc tcagtgatag cttgctcaag caggtcatag tccatctcaa acgtatctgc
     4561 ttggatatcc accatgacag gggttgctcc cacgtgcgta atgacactac atgaagctgt
     4621 ataggtcatg gctggaacga tgacttcatc accaggtccc acttccaaaa cgcgtaaaat
     4681 caactccaga gcggctgtcg cagagttgag acaaacagtc ttaggtgtct gtgtgtaaag
     4741 agacaagcgg cgctccagtt cttttgtttt aggacctgtt gtgatccaac cagaacgcag
     4801 ggtatccgct acttcagcaa tttctgcttc tgtgatatca ggcggtgaaa atggaatatt
     4861 gtaatttggc attgatttgc tccttttatc tgtactcatt ttcttatgac tactttattt
     4921 tagtacctca aacacggttt gaaacatgat tttgatgtcc ccaaagaaac taaactctcg
     4981 gagataggcg aggttatagc gcatcttttc aggaagaaca tgctccacat aggcctgatc
     5041 aactgacaga cctttctccg tcatttgact gatgatggtg tcctcatcct tgtagttgat
     5101 gctggctgga gaggtaattc ctgcttgcaa gagcaaggtt gccatcattt cagggctata
     5161 ctgctctgta taacgtggca cttcaggtcg tgtaccgaca aaggacatct cacctttaag
     5221 gacattgacc aactgaggca gttcgtccaa acggacacgt cggatgaaat ttccaacctt
     5281 ggtaatacgg ctatcgttag cagaagtcac cagacttcct tttttatccg catccgtcac
     5341 catggtacgg aacttccaaa tcttgaaccg acggttgtac tgggtcacac gctcttgctt
     5401 gtaaatcact ggccccttgc tatccaactt gatccaaatg ctcaagatga gaaagatggg
     5461 agaggttaga accagtaaga ccaaggccaa aaaccagtcc aagcaacgct tgaaaatcag
     5521 cgaacccttc cttttagaga caagatggta gtaagactca acctcgcttg atttcatttc
     5581 cacaggcaag tcttcccatt tcagcatact gttctccttt gtttttatta tactatttgt
     5641 caacattttt cattatacca caaaatggaa aaggcggtga aagaaatctg taatttgaag
     5701 gatttccttc tagtactcaa tgaaaatcaa agtacagctt tgagattgca gataaagctg
     5761 acatggttta aagagatttt caaagagtat cggccatggc ccctgcctgc aaactataca
     5821 tcttgtgata ggttcctccc agagtcaaga gttcctcatg ggttccactc tcgataatgc
     5881 gtcccttatc caagacatag atgcagttgg cgtcttgaat agtagaaagg cggtgagcga
     5941 tagcaatagt tgttcggccc tgtctcatct tcgccagaga agcttgaacc aagctttctg
     6001 tttcagagtc aatattggct gtcgcttcat ccaaaatcag gattttaggc tggctggcga
     6061 ctgttctagc aaaggcaaga agctggcgct gcccagtaga gaagctcgaa ccacgctcgg
     6121 aaacagggga gtcgtacccc tgaggaagtt cttgaataaa ggaatctgca tccacaaagg
     6181 ctgccgcagc ctgaacctga tcatcactga tttcttggta catggcgata ttggacttaa
     6241 tagttccatg atagaggaag ggttcctgca agaccaaacc gatgtttttt ctcagctctt
     6301 cttgactgaa atccctgata tccacatcat ccaagagaac tctccctgac tggaattcat
     6361 aaaagcgcat gaggacattg ataatagacg atttccctga acctgtatga cctacaaagg
     6421 caatggtttc acccttatta acagagaaag aaatgtcatc cagaatcgga tgtttaccgt
     6481 catatgagaa acacacatgt tcaaaacgga tattgccttc ttggactttg gcttgcccat
     6541 tttcttgaag aggttcatag gtcctctcgt ctatcagggc aaagacacga cctgcagaaa
     6601 ccatagccgt ttgcagagtt gaaaagtttt gcgtcacctc aatcaagggg tcaaaaaggc
     6661 ggttgatgta ctggataaag gcatacatgg tcccgaccgt tatcccgata gaaaaaccac
     6721 ggtagccaaa gtaggccatc aagactgcat agcctagaag tttcagcaaa ctcatggcag
     6781 gtctcaaaaa gagggcatcc aaggctacag aacggttggc gtagaccaag tgttcttggt
     6841 tgatttcatc aaattctgcc tgcaggcgct tctcttgatt aaaagcctga ataatcctga
     6901 ttccctcgat attctctgcc agcttactat tgatatctga caagagactt ctggttttct
     6961 caatgatttt cactgatttt ttccgataga gattgaccaa aaggaaaatc aaggggagaa
     7021 agagcaagac taatgctgtc aaacgaaaat ccaataccaa catggtataa agggttgtca
     7081 gaaagatgaa aactgctgag ataaagctgg ataaaatccc cgaaaacata tcactgatag
     7141 tctcggtgtc atttgtcaaa cgagagacga tagagcctgc tggcgtcttg tcaaagtaag
     7201 acatgcccag tttctccata ttggcaaagg catcccgacg aatatcccta acaatactgt
     7261 aagacacgcg cgcaaagaga agattgccta catactgaac tacagtttgt aggatgtaga
     7321 gaccatagta gaccagcaaa acggtaacgg ctagttggtt aagattgctg agatactggt
     7381 cgataaagtg ggaagccacg aggggtatga cacttttaat gaccgtcgtc gctaggagaa
     7441 aactgagtgc caaaaaggtc aggagtctat aaggcttgag ataagacatc aagcgcttca
     7501 atacagccca ttgttcttgt ttattctgca tcttcttctc ctttcatttc taactgctga
     7561 gactggtagg tttgggcata ccagccatcc atcgctagca agtcttcgtg cgtgcctcgt
     7621 tcgataattt gaccattttg tagaactaaa ataaaatctg catggacaac agcactgagg
     7681 cgatgggcag tgataatggt tgtcttgtcc tttcgcgtct ccttgaggtt gtcgataatc
     7741 gcatactctg tcttggcatc tacggcggat aaggaatcat ccaaaatcaa gatatcaggg
     7801 tctaaaatca tagcccgact catagccaac cgttgctttt gaccaccaga aagactgact
     7861 cctttttcac caatcagcgt atcaaatcct tgaggcatgt ctacaatatc ttggtaaact
     7921 cgggctagct tagtagcttc ctcgaccgct gaaaggggca agttaggatt gccaaagcgg
     7981 atattgtcta ggattgaagt tgcaaagaga aactggtcct gaggaacata gcccatgaga
     8041 ctgcgaaggt ctgtcagacg atagtcccga atatcgtgac cgtttagata aatggcaccc
     8101 ttatccacat cgtattcacg caagaggagc ttgattaagg acgttttccc agagcctgtc
     8161 tgcccaacca agcccagtgt ttgccctttt gccaaactaa agtgaatatc cgtcagtgtt
     8221 tcctcatttt caaaagcaaa gctgtcaatg gcatactcca aacgcccatt ttcaatacca
     8281 tccagaggaa actcagggtc ttgtacagga gattcctgag acaaaagatt ttcaatccgc
     8341 tggtaagaaa ccttccctcg ctgagtagta ttaaagagga agccgatggc cataagaggc
     8401 cagaccagca tatccaaata gctgataaag gtgactagat tcccaactgt aatctgccct
     8461 tcctgaacca tcaaggagcc aaccaaaagc gttaaaacat aggacgaacc aacaaacacg
     8521 agaaccatag ggtcaaagag actatcatat ttcatggttt gcaggttctt ttggaaggtt
     8581 aattcattga ctgcctgaaa agacttcaac tcgtctgcct gataaccgaa agacttggtc
     8641 actttgatac ctgatacgga ctcctgtacc ttgttattga gttcagaaaa agcagcttgg
     8701 gattcgccaa aggccttatg agtctttctc cctaggcgac tagtcgcata ggccatgaaa
     8761 ggtaggggga gaatggcaac aagagtcatc tgccatgaga tgctaaagag catggtcaac
     8821 aaagtcacca gagccgtgat agaggcatcc accgcagaca tgacaccgcc acctgctaaa
     8881 cgagtcaagg cattgatatc attggttgcg tgtgccatca gatcacccgt ccgataggtt
     8941 tgataaaagg ctgatgacat ttttgtgaaa tgcttaaaca agcgagaccg catgatctgt
     9001 cccaagcaat aagaggtccc aaggatatac atacgccaca catagcgcaa atagtacata
     9061 ccaaaggctg caagtagcaa gtaaaatagg ctaagaagga ggtcctgctg ggttaattgc
     9121 cccgatgtga tggcatcaat gacccgcccc ataaccatag gaggaatgag attgagaacg
     9181 gaaaccaaga ccagggccac aatcccgact agataacggc gtttttctaa cttgaaaaac
     9241 caccaaagtt tttgaataat ggacataaaa tccctttctg attgcaaatg gaaacctgag
     9301 gccaatactc aatgaaaatc aaagagcaaa ctaggaaact agccgcaggc tgctcaaagc
     9361 actgctttga ggttgtagat agaactgacg aagtcagtaa cctacatacg gcaaggcgac
     9421 gttgacgcgg tttgaagaga ttttcgaaga gtacaagacc ccaggttttt ctttttcata
     9481 agttacgact gtaacagcac ccttgtcata ttcagcaata aagatattgg ctacattgtc
     9541 atgcccttgt ttactgaggt tatcaagcaa ccactcttcg ctacgaccaa tcgattccaa
     9601 gacatctact tgaatcacac cgtcagtcac aactggatac ttaggatttt catctcccat
     9661 ttgcacaacg ataagttgcc cattttgctc ttgcacagct cgtttgactt gcttcatctg
     9721 gaaaatccct tggctacgaa gtttgagggc tacatccgat gcagacaaac caactgaacg
     9781 acaggcttct gggtcaatat tcccattttt gataaggaga gttggcttac catcaatcaa
     9841 acgtttcaca aagtgaacat tgttgttgag ccatttgaga gtcaagacca gtttgattaa
     9901 aatttcgata taattaagtg tcatttgttc acatccacca gttcaattgc gtctgtctta
     9961 tacaattcga ctttctctaa caggtacttg tctggctcac ttccgtttag ggcacgataa
    10021 tagcgatctc ccaccttgat aagtgcgcca tctgtgtttg tggaagtatt aacatagact
    10081 tctgacttgt ctactcccaa atctttggaa acaacctcga tgaaatgaag tgaagtttga
    10141 aatttattgt tagaaacttg attgttttga taagtcgtga tgctgaccaa aagcagagct
    10201 aaataaggcc agagctgaaa tcatgaccaa ctcacgaaat tcggttccct ttttatcatg
    10261 gtatgccttg aaagcaaaaa aaactgtcac agctaataga acaatcccaa agccaaccat
    10321 gataccattt tgctgaccga tttggctgag tacatagtca taagagtaga atttcatata
    10381 ttttcactcc ctttcataaa atcattctta attataaacg aaagagagta atttttcaaa
    10441 ccatacgttg gggaaataga tctttttttg gtataataaa atctataatc tgaatgaaaa
    10501 aggtaacttt atgaaactta tctcatggaa tattgattcc ctaaacgctg ccctaactag
    10561 tgactcagct cgtgccaaat tgtcccaaga agtcctacaa accttggtcg ctgaaaatgc
    10621 tgatatcatt gctatccaag aaaccaagct ttctgccaaa ggacctacaa agaaacacgt
    10681 ggaaatttta gaagaactct tcccaggcta cgaaaacaca tggcgctctt cccaagagcc
    10741 tgcccgtaaa ggctatgctg gaaccatgtt cctttataag aaagaactta cgcctacgat
    10801 cagttttcca gaaatcggtg ccccttctac catggacttg gaaggccgta tcatcactct
    10861 agaatttgat gcatttttcg taacccaagt ttacactcca aacgctggtg acggtctcaa
    10921 acgcttggaa gaacgccaag tctgggatgt taaatatgct gagtatttgg ctgaactaga
    10981 caaagaaaaa ccagtccttg cgaccggtga ctacaacgta gcccacaatg aaatcgacct
    11041 tgcaaatcct gctagcaacc gccgttcacc tggatttact gacgaggaac gtgctggatt
    11101 taccaacctt ttggcaactg gatttacaga caccttccgc catgttcatg gcgatgttcc
    11161 tgaacgctac acttggtggg cacaacgcag caaaacttct aaaatcaaca atacaggctg
    11221 gagaatcgac tactggctca caagtaaccg tatcgctgac aaggtcacta aatctgatat
    11281 gattgactca ggtgctcgcc aagaccatac accgattgtc ttggaaattg acttgtaagg
    11341 attttctata tggactacaa tgcggtcatt cccgagtttc ttgtatcgaa tatcgaacag
    11401 tcccggtcct tctactgtgg tttactgggt tttaggattg aatactaacg tccagaagaa
    11461 aactttctct ttctcttgaa gagtgtcaac taatgttaga ggagggaaca aaggatcaac
    11521 tagctgaact gacctacccc tttggtcgtg gagtcaatct ctcctttggc ataaaggatg
    11581 ttccaaaact ctatcaaaaa gtgatggagg caaactatcc tatttatcgt ctcttgacca
    11641 aaagaaagtt tcgtgtcagt gatccctata tctatcctca taaatttgca gttttggatc
    11701 cagatggcta ttttttaaga tttagcgagt agaataataa aaattgggaa aagtctttaa
    11761 agttagaaaa aggcatattg tcaggtgtct aaaaacttga tagtatgcct tttatgatgg
    11821 aaaaatcttc taatactctt cgaaaatctc ttcaagccac gtcaacgtcg ccttaccgta
    11881 ggtatatgat actgactctg tcaattctat ccacaacctc aaaacagtgt tttgaggttg
    11941 tggatagctt cctagtttgc tctttgattt tcatttagta taaatgttag cttacaatga
    12001 agtttttgtt caccctctct tctttttgtt cgctttttaa accaaaacac taacaaaata
    12061 gttgatttct aaagttattt agtgtaaaat aaaaacattg gctcaagcct atttaaaatt
    12121 gaatatcgtt ttacttgttt atgtcgtgaa ttggcacgac gtttctacaa ggtgccggaa
    12181 cacctaacaa taagtaagtc agcagtgaga tatggccgtt tttgccatgt ctatttaggg
    12241 gacttactta gagattaagt aggtcttttt tgaatatttt taatatttcc cttaattagt
    12301 gcggacggga ggtgaaatta tcctgtgaat aatttcagga atccagggaa tttcatccct
    12361 aatttttgag cccctagctc tttcatttct aggcttaggc taaaatagtt ccccgaacta
    12421 ttttactctc aaaaatcccg tcatagacaa taacaagatt attgtctatg ataccactac
    12481 aacgggaaat atttgataag actcgcttcg ctcgtaatag ttttatcaaa tatatagtat
    12541 tagcaaaagg gatcactata gaaatattta aacaacaagt aaattaactt ttagacttta
    12601 ggaggtctta tgaaattatt agaagagcgc atcctcaagg atgggcatat cttgggtgat
    12661 aacatcctca aggtagattc ctttttaacc caccaagttg actttagctt gatgcgagag
    12721 attggtaagg tttttgcgga aaaatttgct gctactggca ttaccaaggt cgtaaccatt
    12781 gaagcgtcgg gtattgcccc agccgttttt acagctgaag ccttaaacgt tcccatgatt
    12841 ttcgccaaaa aagctaagaa catcaccatg aacgaaggca tcttaactgc tcaagtctac
    12901 tcctttacca agcaggtgac cagcactgtt tctatcgctg gaaaattcct ctcaccagag
    12961 gacaaggttt tgattatcga cgatttcctt gctaatggcc aagctgctaa aggcttgatt
    13021 caaatcatcg aacaggccgg tgccacagtc caagctatcg gtatcgtgat tgagaaatcc
    13081 ttccaagatg gccgtgattt gcttgaaaaa gcaggctacc ctgtcctatc acttgctcgc
    13141 ttggatcgtt ttgaaaatgg tcaggtcgta tttaaggagg cagatctcta atgcaaactc
    13201 aagaaaaaca ctcgcaagca gccgttctgg gcttgcagca cttactagcc atgtactcag
    13261 gatctatcct ggttcccatc atgattgcga cagcccttgg ctattcagct gagcagttga
    13321 cctacctgat ttctacagat atcttcatgt gtggggtggc aaccttcctc caactccaac
    13381 tcaacaaata ctttgggatt ggactcccag tcgttcttgg agttgcattc cagtcggtcg
    13441 ctcccttgat tatgattggg caaagccatg gtagtggcgc tatgtttggt gcccttatcg
    13501 catctgggat ttacgtggtt cttgtttcag gcatcttctc aaaagtagcc aatctcttcc
    13561 catctatcgt aacaggatct gttattacca cgattggttt aaccttgatc cctgtcgcta
    13621 ttggaaatat gggaaataac gttccagagc caactggtca aagtctcttg cttgcagcta
    13681 ttactgttct gattatcctc ttgatcaaca tctttaccaa aggatttatc aagtctatct
    13741 ctattttgat tggtctggtt gttggaactg ccattgctgc tactatgggc ttggtggact
    13801 tctctcctgt tgcggtagct ccacttgtcc atgtcccaac tccactctac tttgggatgc
    13861 caacctttga aatctcatct attgtcatga tgtgtatcat cgcaacggtg tctatggttg
    13921 agtcaactgg tgtttatcta gccttgtctg atatcacaaa agatccaatc gacagcacgc
    13981 gccttcgcaa cggttaccgc gcagaaggtt tggccgtact tctcggagga atctttaaca
    14041 ccttccctta caccggattt tcacaaaacg ttggtttggt taaattgtca ggcatcaaaa
    14101 aacgcctgcc aatctactac gcagctggtt tcctggttct ccttggactg cttcctaagt
    14161 ttggcgccct tgcccaaatc attccaagct ccgtcctcgg tggtgccatg ctggtaatgt
    14221 ttggttttgt atcaattcaa gggatgcaaa tcctcgcccg tgttgacttt gctaacaatg
    14281 aacacaactt ccttatcgca gctgtttcaa tcgctgcagg tgtcggtctc aacaacagta
    14341 atctctttgt cagcatgccg acagccttcc aaatgttctt ctcaaacgga atcgtcgtag
    14401 ccagcctact cgctattgtc ctcaatgccg tattaaatca taaaaagaaa taagaaaaag
    14461 aggtgcgagc ctcttttttg ttgacaaaat aaaaacatct acctattcat atatgctagt
    14521 gtcatagtcc tgaaaatcat ctgcatcaag aacaatttca caactcttat acttttctct
    14581 tacaagtcgt tcggcttcat ctggattttc agcctctata cttactaaac gtgataaagt
    14641 ttctgtaatt tctactgtat actttttcag ttttagattg ctttccaata attcacctat
    14701 taacaataat ctatgatagg agctatgtag ccactctggc aatttatctc ctacttccca
    14761 cccatatttt tccttcatca aagctagttg tttttcgtca ccaaatttca tattttcaga
    14821 taaccatctc acacaatcgg gatctgataa ggtacagacg attaaactta ggttatcgta
    14881 acggctttca gtttcataat caggccagat gacttttaag aaatcataca cctcttctga
    14941 tgcaacaagt tgtttcgttt tcataatttc cgatactttc ctctaccttt aaattctatt
    15001 atttctttgt ctcttaatat ttgaagctgt tgcctaatct tttctttgat atgattgttc
    15061 ttaacaaaga tattttttag gtcactttca aaacgataca tatcttcaag ggtaaattct
    15121 gaaccctcta tcttatctat acaatttaga atttctattg tccaacctct tgatgacaga
    15181 gagctcttcc ttaaaaataa accttgctta aattcttttg taactttttc tggatctcta
    15241 acttgtccat cttgcacaag aaatatcctt cctttagaag gtacttgtga taaatcaatg
    15301 ttacaaccaa tccaacctgc tcgtctagca gttggtgcaa gtggttttct ttgaataatc
    15361 gatttcggtg taacaaattg cttcggaagg acaagaaagt tatttacctc aaaatttttt
    15421 gtgtaagtta aaaaaaagaa attaggatta ttatctgcct gcacacgctt catcatcgtt
    15481 gcataagcac catcattgat tgttgatgaa aaatttcctt ttttgctctt tagttcaaac
    15541 tcctcactac aatgattaca gtaaaaatct gctacaggcc gattattttc aaaatgattt
    15601 aagggattgt tcccacaatt agggtaataa gactgacgat aaacccaatc ctccgttaag
    15661 atacgtgcct tttggctatt acttttatag gtttctacta attctaaatt aaagtgtaat
    15721 tccatttaaa aattcctcac taatatgaga actcactcga tataagcaat taaaatctac
    15781 tataactagt ataccacata tatgtaccta ttacatttgt atttcatcac tctcttttat
    15841 atttccttct aacatatctc ataaattaaa aatgagtgag ataaatttat cccactcacc
    15901 tttctttata tccttacccg tctttcctca gacctttggc ctatgacaaa catggtaaag
    15961 gttgctttgc agacatttct gccctcttga ttggtgatat ccacatccat cacacaggtt
    16021 gtacggcctt gatggacaca ttctccttta atggtcaata catcgtcgag ttttcctgcc
    16081 ttaaggtagt tgatagagga ttggagtgtc accccatcaa gtcccagcga gataaccacc
    16141 aaaccactga tttggtcaca tagcgtgaat agatagccac catgggcatt gccatagtag
    16201 ttgagcgacg agttcactac tttggtcgtc accacaacgt gaccatctct cattttttca
    16261 atttcgtaat tttcaaaggc agatatagcg tcaaaatgaa agtctttcat cgtttcctcc
    16321 tgatatttca aacgacacta tgatactact ttttatagga ctgtgcaagg agaaagctcc
    16381 tagtctagta aaattccgac atgttccaca aagcgcataa aggctgtctg cccttgttct
    16441 gtctgcttgt agactcctgc atcctcaagt acacgcgcaa agatagcacc cacagagtcc
    16501 ttgacgattg caagggcttt ttctttatcc gttaggtctg gatgttggga tttgagttgg
    16561 tctgcccact cctgatgata atcggcaact gtaacagctt ctcctacaag atagctcgcg
    16621 acttgctcca cttcttcttt cagacgtggt ggcaagattg ccaagcccat gacctcaatc
    16681 aagccgatat tttccttctt gatatgttgg acatccttgt ggggatgata gataccatca
    16741 ggatactctg ctgaagtctg attgtctcgc aagaccaagt ccaactcaaa ctgtccatcg
    16801 cgtttgcggg caatgggtgt gatagtgtga tgcggtgtcc tgtctgtctc tgccaaaatc
    16861 tgcactgcag gatctgaata ctggcgccat tcctgcaaaa tcttatcagc caaattgatc
    16921 aaatcctctt tggaatccga agtcaaacgt aggacagaca tgggccactt gacaattcca
    16981 gccttgacct gctcaaaacc agcaaatcgg aaggcctttt gcaagggagc caattccata
    17041 ggaaatacgt gacggcctcc ctgataatga tcatgagtta gaatagagcc ccccacaatc
    17101 ggcaggtcgg cattagatcc agcaaaatat cctggaaact ggtctacgat agccaacaga
    17161 cgttcaaaac tctgacgact aatggccatg ggacgatgct ggccatctaa aaagatacaa
    17221 tgctcattaa agtaagcata gggcgaatac tggaaacccc attcctgacc aaccatttca
    17281 aaacggataa tacggtgatt gctacgagct gggtggttaa ctcgaccatg gtagccctca
    17341 ttctctagac aaagctgaca ctgaggataa ttactagctt gcaccaactt ggctgccaca
    17401 atctctttcg gatccttttc aggcttagag agattgatgg taatttcaag ttctccataa
    17461 tcagatggaa cacgataagc gatattttta gcaatggcct tgagtttgat gtagtcattt
    17521 ttctgactga gttgataaaa atcctctatc gcttgctcag gatagtggac ataggtttcc
    17581 cagaagtcac gattgacctg actcggacaa ggagtcacca agtccatcag ttcagtacca
    17641 aggatttcac gcgcagtctg actatcctca atcgtctcta atcgaacggc ttcctcaact
    17701 agctggtcct tgaggtcaat caatttatcc agattggtct caacttccaa aacaccttct
    17761 cccactcgtg ccaaaacacg attggtcagg tagattcgat ccatttcctc aaatgaactt
    17821 tcagaaatga catgtgttac aaatttatct actaaggtca ccatagagcc tccttttgac
    17881 tagtcaagga cgtgagtgcc acctgcaact tcagcgatat agaagcttgg agcgtatcca
    17941 actacttcct cgtagtgttt gcctacagtt tccttaaagg cctcaacagt atctttttga
    18001 accaaggcaa tggcacagcc accaaaacca gcccctgtca tacgagcacc gagaactcct
    18061 tcttgtgccc aagctgtgtg aacaagagta tccaattcca aaccagttac ttcataatca
    18121 tgctccagag aaacgtgtga cgcattcatc aaacgaccaa atgtttccaa atcacctgct
    18181 tgaagggctg cttgagcttt aagggtacgt tggttttcaa gcacagcatg gcgagcacgt
    18241 ttcaaacgat tttcatcttt aatcaaatag ctatattggt caacggccca ctcgtccaat
    18301 tcacccaggg tctgaatatc caaggcaact tgcaattctt ccactgcttt ttcacactca
    18361 gcacgacgtt cattgtattt agagtccgcc aattcacggc gtttgttggt gttcatgata
    18421 acaacgacat tgtccttcaa atcaagtggc accaaatcat actctaaggt gttggtatca
    18481 aggtaaatag cacgttgatc ggcccccata ccaatagcaa actggtccat gataccagag
    18541 ttgactccga taaagttgtt ttctgtttgt tttccgattt taaccaaatc gagacgctct
    18601 aattttaaat caaagagatg ctctgccacg actcctgtca agagctccaa ggatgctgaa
    18661 gaagacaagc cagcaccatt tgggatattc ccataaacat aaaaatcaaa acctttgtca
    18721 atcacgtgcc cagcttcttg caagaaatga aggacacctt ttggataatt ggtccagttg
    18781 tgctcttttt caaacttgag gtcagcgaga ggcacttcga taatgccctt gtcctcaaag
    18841 ttagctgagt agaaacgcaa gacttggtcg tcacgcttac gagctgcacc gtaagttccc
    18901 aaggaaatag cagcaggaaa aacgtgccca ccgttgtagt ctgtgtgttc accaatcaaa
    18961 ttaatacggc ctggtgaaaa gaaggtttgg tctgcttctt gaccaaaaac agcaagaaag
    19021 tctttgcgaa ggacttcagt agtaagatgt tgtgccatat gaattctcct ttgactgtcc
    19081 gttaagccat cttaacgtgt aatcgttttc tttctattgt atccaaggaa tttcccaagg
    19141 tcaatccttt ttactaaaat tttactaaaa tatcagtaaa aagaagaaaa atatgatata
    19201 ctaacctaat caaggaggat ttatggctac cttaaaagac attgcacagc tagcctctgt
    19261 ctcaatcgcg accgtatccc gtgtcctcaa ccgcgaccag agcctatctg ttacagaaga
    19321 aaccagacac cgtattttaa ccgttgctga agagctaggc tacaccaaac acctcaagac
    19381 aggcgagtcc cacaagccca agcaaaagat tgccattatc caatgggtca gcgaacaagg
    19441 ggagctagac gacctctact actaccagat tcgcctagga atagaaaaaa gagcccaaga
    19501 gttggactat gatatcttgc gctattttaa tgaccatcct tttaccctaa gcgaggaagt
    19561 gattgggatt ctctgcatcg gaaaatttag ccgagctcag atttctgcct ttgaagaata
    19621 ccaaaagccc ctggtctttc tagacagtga tacactttcc ctggggcata cttgtattat
    19681 tacggatttt tacactgcta tgaaacaggt tgtcgattat ttcctcagtc aagggatgga
    19741 ccgcatcggg attctaacag ggcttgagga aacaacagac caagaagaaa tcattcagga
    19801 caagcgtcta gaaaacttca aaaactacag tcaagcgagg ggaatctatc atgatgaact
    19861 ggtctttcaa ggaagattta ctgcccagtc tggctatgac ttaatgaagg aggccattca
    19921 gagcttggga gaccaacttc cgccagcatt tttcgcagcc agcgatagtt tagctatcgg
    19981 tgccctccgt gccctccaag aagctggaat cagcctgcca gatcgcgtca gcctcatttc
    20041 attcaacgac accagtctga ccaaacaggt ctatcctccc ctctctagta ttacagttta
    20101 tactgaagaa atggggcgag caggtatgga tattcttaac aaggaagtcc tccacggtcg
    20161 caaaattcct agcctgacca tgctgggaac cagactgaca ttaagagaaa gtaccctaaa
    20221 tcaagaatag gataacataa aaaacgaata gagttctaaa actcctattc gttttttatt
    20281 cgattacaat catagactta attgtcttac gttcatccat atctttatag gcttggtcga
    20341 tatcttccag tttataactt gaagtaaaga cgcgacctgg attgatatca ccatcaagga
    20401 cggcttttag taaaaattgc ttatcgtatg ttgtagcaga agctgcccca cctgctacag
    20461 agatattttg cataaatgtc gaaccaagag cacgattatt atagtgtggg actcctacaa
    20521 agcccatacg ccctccatta tgaagaacac ctagcgcctg ttctatagca gcctccgtac
    20581 caacacattc aagtgctgcg tctgctcctc cgccgaggat ttcacgcacc ttggtaattc
    20641 cttcttgacc acgttctgca acaacagctg tcgcacctga ctccatagcc atcttttgac
    20701 ggtcttcatg acggctcata aggataattt gtgatgctcc acgcatctta gccgcgatga
    20761 cagcacattg accaacagcc ccatcaccga taacaacaac cttgtcccct ttttgaacat
    20821 ttgcaacacg cgctgcatga tagcctgtcg gcatgacatc tgcaagagtc aaaagggact
    20881 tgagcatccc ttctgtataa tcagaaggtt gaccagggat tttaaccagc gcccagtttg
    20941 catagtggaa gcgaatatat tctgcctgaa aatcaccccc caaattatta ccaatatgat
    21001 tgtcgcaaga accgtcaaat ccagcaagac aggcatcaca ctcaccacat ccatgtgtaa
    21061 aagggacaat cacaaaatca cctggtttca ccgtcgtaat ggcttcccca gcttcttcaa
    21121 caatcccaat cgcttcgtgt ccactatttt tatgtccagc tttcgtttct ggattacggt
    21181 acctccataa atctgaacca caaacgcacg cacgaaccac acgaataatc acatcatccg
    21241 cttctattat ttgcggacgt tcaatgctag caagtccaac ctgacctgcc tttgtatata
    21301 ctgctgattt catttaaaat tttccttcct tataaagttt aattttgaga tttaaacgat
    21361 ttaaagctgt ctgtagctga gacaagcgct cctctaattt ttgcttttcc tcttctaaaa
    21421 taccaagcct ctcctctctc gtttcatctc ccttttggta gagcgacata tagtcaacta
    21481 aactatctac agagacaccc gccgaacgaa aacacttaat aaattccagc gcttcgatat
    21541 cctgatcttg aaaatcacga atcccagtag cagtacgagt aatcggtggc acaagaccaa
    21601 cccgttcata ataccgaatc gtatccgctg aaattcccaa caaatcactg gcagatttaa
    21661 tattcacacg ctaacctcct ctcatttcat tcactgaatt cacgctattc taactcactt
    21721 atcttattat ataactttga gttgactcca agtcaagcat tttgtatcta atcgaaaaat
    21781 ttttatcatt aacaatcata tatctggagt ttatacaatg ctcttctctt accaattttt
    21841 gaaatattta aataataaag aaattactct attccaaata agatagtacc caagtatttt
    21901 tcactttttt ctaatgttga tgctcataac tccgttccaa gtcacacacc tttcgcttat
    21961 gggtttggtg agtttctagg tcagcatcaa tttcaatggt aatattttga aaaccacaat
    22021 cttttaggaa aattcgaata gactctttac aagtttccat atgttccatt tcttttagac
    22081 aaacatgtac aatggcattt ttttccaaag catccatagt ccagagatta agctgattaa
    22141 ggctggccac attgtccaat cgctccaggc cactctttac ttgcttgata tcaagacctt
    22201 ctggcacagc atccaagaaa atcttgagtg tagaccaaaa acgtggaagg gcttttgaaa
    22261 gaataaagaa agaaatgaca agggacaaaa gaggatctag gatataccag tccgtaaatc
    22321 gaagaacaat cgccatcagg ataacagcta cccaccctag cgtatcttcc agaaaatgca
    22381 aactcagaat agactcattc tttgtctttc ccttaccaac caccagactc gctaacagat
    22441 tgatagtaat cgcaataatt cctaaccaga gaatcccctc atcattgact ggttgcggat
    22501 gcaaaatctt cgtgacattt tccaaaatga ctagaacaga gcccgttacg agaatcacag
    22561 ctgttaccaa ggctcctagc aggctaaacc gcttatagcc caaggtgtac tgattgtctt
    22621 cttcacgatt ggagattgtt tctagaaaag ctgatattcc aattgcaatc gcatctccca
    22681 agtcatgcac agagtcagca agaacagcgc tagaaccaaa tactccacct gcaataaact
    22741 caacaatggc ataagtcaaa tttaagaaaa aagccaccca aacagcatat tttgccttca
    22801 tatttctcat tcctttgtta taatagattt atgaacacct tgttcattat cattatccac
    22861 taaaactcaa agaaaggata gaagcaaaac gtcagcttta ttcagttctg aacaatttgc
    22921 cttaagtgtc catatgacta acattgaccg ccgtatcagc aaaaccaaaa aagccatcta
    22981 tcaagctttt atacaacttt tgaatgctaa gggctacgag gccactactg ttcaggatat
    23041 cattgatctc gcagatgtgg gaagatccac cttttactgt cactatgaaa gtaaggagct
    23101 tcttctggac cagctctgcc gctacctctt ccatcatctt tttgaaagag agcaagccat
    23161 ttcaaccgag gactacctcg cccacctctt tctccatttt cagaaaaacc aagaccatat
    23221 caccagtctg ctattttcca aaaatgacta cttcctccgt caactccata aagagctaga
    23281 acaccatgtc tattccgtgc tagctgataa tttaaaagaa gcccacccta atatgcctac
    23341 ttcttacctc caacacttgg tcgtgtccaa ctttatcgag acattgacct ggtggctcaa
    23401 aaaaggtcaa gatttcatag gccaggaagt tgtccaattt tatctagacc ttctcattcc
    23461 taaaaattga atatagagta aagctcagtt gtcttatttc taggttactg agttttttat
    23521 cttttcaaca acaaaagagg acccgccgat cctctttttc atactataaa tccttgatta
    23581 tcaactatat ctgttttaat cgaaatctca aaacagcact ttcaaacatc ttttcctagt
    23641 taagtaaatc agtattctgc ttagctgcct tgctccattg ataccaacca actagactgt
    23701 taatgagata aattagatat ttcccttgaa tttgcaggct ttctccccac cagagataga
    23761 ttgaaaaaac attggtagcc gcccagaata tccactgttc acggtaaaca gctgtcatga
    23821 ggatttgccc taccccattg gttgcatctg tgattgaatc acgataggga cgattggcac
    23881 caatagactg ataaatgaag ccaaaggcca accaccaaag cacactaatg gaaagatact
    23941 ttgtccagcc cttgccgtcc agtttacgcg cgacaaactc ctgcttttcc ttcttaaact
    24001 gtgcctgata aatccaaact agaagtccaa ttggctgcat gactgtgaag taaagtgtcg
    24061 tcagcacctc accataaaag cctttctgta gggccaaaat aaggtaaata acagagttaa
    24121 tcaagccaaa aagataatta cttgctcgac cttccgatac aaagattaca cagataatcc
    24181 ctgtcaagct acaaatcatc ccaatccagt caacaatacg atgttcgtaa accaactcca
    24241 gccagagagg aaaacttcct aaaaccagca aataaatcca ctgggcaaaa ctacgatggg
    24301 caaagaggtc atcccagata gccttcatag ttcctgaaaa tcctaaatca gccatagccg
    24361 caaccatacg acggtaacca cctgacattt cacctagggt tgttttgata ttttcaattt
    24421 tcttttgcaa ataagtatgc atcatttctc cttttgtttt taaagagccg tgtctggata
    24481 gactttcgga cgcaacgctc tattagataa tgaactgcct atacacaaga tttctaacct
    24541 tagtcgacat gagctaaaac ctcttatttg ttaagtagtt cacaaaatat tatacaccta
    24601 ttttatgaat agtcaactgt ctttacagta aaattttaga aaatcatgaa aattttctct
    24661 ttctttccat tttaagtgac attcagtcat tctcacatca aaaaagccca gacgaaattg
    24721 tctgagcatt cttttatcta gtcgtttaag gaagttgagt tcagtatgtt taaagtctct
    24781 gtcccatcat ttcttcaaca aaccttgttc ttggagaaac tccttggcta cttgctttgc
    24841 tgacttgcct tcaacaccga cttggtagtt gagctggctc atctggcttt ctgtaatctt
    24901 accagccaat gtattaagaa ctctttccaa ctctgggtgt ttcttgagaa gagcttcttt
    24961 catgagtgga gccccttgat aaggtgggaa gagttgcttg tcatcttcca agacctgtaa
    25021 atcataacgc tccaattccg catcagtcga ataggcatcc gtgatttgaa tatcccctga
    25081 ctgaattgcc tgataacgaa gagctggctg catagtcgcc acattgagat tgagaccata
    25141 cattgattgc aagcccttat ttccatcttc acggtcgtta aactcaagcg taaagcctgc
    25201 cttcagctgc ccttccactt ttttcaaatc cgaaatggtc ttcaagccat attcttgcgc
    25261 aatctttttc ggaacagcta cagcataggt attttgataa gacataggtt tgagataggc
    25321 tagatgatcc tgcttggcaa tgctatcacg cgccacttga taaacctgct ctggctcatg
    25381 actcaccttg ggtgatggtt gaagcaaact ttcagtcacc gtaccggtaa attcaggata
    25441 aatgtcaata tcaccttttt tcagagcttc ataaaggaaa cttgtcgtcc caaaattcgg
    25501 tttaacagtc gcagtcatgc tggtattttc ttcaatcagc aatttataca tattagccaa
    25561 aatttctggt tctgggccta ttttcccagc aataatcaag ttttccttct ctttttgagc
    25621 caaaagggct ggactataag acagacccag taataaagcc accaaggcaa aaccagagaa
    25681 aatcgtccgc aatttcgctt tttccattac ttttagtagg aagttaaagg caatagctag
    25741 cactgcagaa gaaagggccc caatcaaaat caaactggca ttattacggt caattcccaa
    25801 caggataaag gaacccagtc cccctgcccc aatcaaggtc gccaaggtag ccgtaccgat
    25861 aatcaagacc gctgccgtcc gaattccaga catgataaca ggcatggcaa gtggaatttc
    25921 aaacttcttg agacgctccc atctggtcat cccaaaggca atcccagcct cttgaagact
    25981 cggatcaatt cccttcagcc cagtaatagt attttgtaaa atcggaaaaa tcgcataaat
    26041 cactagagct gtcaatgccg gtaaagtccc aattcccatc aagggaataa agagtcccaa
    26101 caaggccaga gacgggatgg tctggaaaat ccctgcaatc tgtaagaccc aatccgccaa
    26161 cttctcatga tagcgaagaa aaacagccaa gggaatcgca agcaaaatag ctagtaacaa
    26221 ggtcaaaagt gacaactgca aatgttgaga tagagctgtc aaccaatcac taaaacgatc
    26281 ctgaaaagtt gcaattaaat tagtcatgaa cactacctcc aaacaagtct gctacaaagt
    26341 ctgttgcagg cgcttttaaa attgtctcgg gattcgctac ctggcgaatt tctccatcct
    26401 gcaagacagc aatacggtcc gccaacttca aggcttcatc cgtatcatgg gttacaaaaa
    26461 tcgttgtcat cccaaactct ttatgcaatt cttttgtcag aacctgcaac tgttttctcg
    26521 aaatagcatc caaggccgaa aagggttcat ccatgaggaa aatcttgggc tgaccaatca
    26581 tagctcggac aataccgacc cgttgctgtt ctccaccaga taattcacta ggtaagcgat
    26641 gcccatactc ggctactggt aaaccaacct tagccaaaag ctcttctgtt ttcttcgtaa
    26701 tttcttcctt gctccacccc ttcatttcag gaatgagagc aatattttcc gcaactgtta
    26761 gatttggaaa aagagcaata gcctgtaaaa cataaccagt agaaagacga agttcacgct
    26821 catcatagtc tttgatgcgc ttcccatcca tataaatatt tccatcagtt ggttccaaaa
    26881 gacggttaat catcttgagc atggtcgtct tacctgaccc agaaggccct actaaaacca
    26941 taaattcccc atcctcaatc tgtaagttga catctctcaa gacatccttt tctgtgtagc
    27001 atagtgctac atttttgtat tcaatcattc tttgtcctca tttaaaactt ccctcgattg
    27061 gtcaagtctt ctaccttagg catgacttcc ttattatccc aatgctccac aattttcccg
    27121 ttctttaaac ggaagatatc gtactgggca taagcaacgc catcaatctg agtctgacca
    27181 tagctaacca catagtttcc ttgtcctaag agttggaaaa caaagtcaaa agtgacacta
    27241 tattcagcca catagttttt ataagcagca cttccttgtc caatatcatg attatgctga
    27301 atcaaatcgt ctgccacata atcactccac tgctctagct ccccattttg gaaaatttct
    27361 gtcaagaaac ggcgaaccag ctttttattt tctgctttct tgtccaaatc cttgatttca
    27421 aaatctccaa aaatttgatc tagttggtca ttttcaggtg ttcgatagta gtcaatgaca
    27481 tcccaatgct caacaatacg accattctca tccgcacgaa aagtatccgt cgtcacccat
    27541 tgagcttctc caccattcag atattgatga acatgaacaa agaccagatt gccatcctca
    27601 atggtgcgga caatcttaat ctgacgctct ggatgacgct caaagaaatc tgcaaagaag
    27661 gctgcaaatc cttctttccc gtcaggaaca cctgtcgaat gttggatata ggtagcccct
    27721 acagactggg cttgagcctc agcaactcgt ccgtcttgaa tggcatggat gtataggttg
    27781 tgagcatttt tcacttgttg tgacatattc taaacctcat ttcccttctc tttcagattc
    27841 gccaaaattc tttcttgaaa accttcaaat tggtgaattt cttcctctga aaatcctttg
    27901 taaaagatag tatccaattt ctgactgaca cgatgcccca cttctttctg ggacttgcct
    27961 aactccgtta aaactaaata cttcttacgc ttgtcttttc cacacggact aacaattaca
    28021 agcttttgtt cctctagctt ttttatcata gtcgtcagcg tattattcgc aagtccagtc
    28081 gcaagcgcga tatctgtcgc agttgcgcag ccagtttcac tattccataa aaccgctaaa
    28141 atcttgccct gttcacccct ataaagagcc tcaggatctt gactcagtaa cttttgaaaa
    28201 atccgcccat tcaacaaacg aatatgatgg gctagcaaat gaccatcttt cataacacct
    28261 ccaatttatt tcgatatcga aatgaataaa acaattgtaa cactcatcgt tctaactgtc
    28321 aactatttcg atttagaaat aatttttgat aattatccac accaccatac tccggctcaa
    28381 ctaactttta acgagagttt ctaaactcct tcgtcctcca gtctacaaaa gccttccatc
    28441 cgtactatcc tatattttat gaggggacac atttttccta tcagaccatt tattttaaag
    28501 atagaagtaa atcataattg cttccatctg ttcttttata gtatattgaa gttggactag
    28561 ggcactgtat cttctaaaac attgatagaa agcgatttga atttcccaat caatttgttc
    28621 gtctttatag catttcgaaa ctggaatagg acaccatgac tgctaaaaga tttctataaa
    28681 ttcatttgat ttcctcaatc aatttgttca tatcttattt cattccgcta taatttcacc
    28741 ttaccctatc tttttcgtag cacccttcaa acagcctatc ccctaccgtt tgacgattcc
    28801 tcacttcact ccacttccat tacagaagtt tcttcactac tatggtctcg gctgacttct
    28861 catgattcct tgttactact atttgaacgc tcacgagata ggtcttataa aaaatgcttt
    28921 gatccacaat ggaatcaaag cattttaaaa agttcctcat acataagtgc agaagtcgca
    28981 gttcctctgt acttggcttc ttctcttttg ataaagcgag ccaagttgag caactcaggt
    29041 gctggatgtt tgggatttag gagcaattca cgattgacca ggcctgagag acgaactgcc
    29101 tgcaattgct catttgtagt aggcagtttt ttagtagtct ctaggagagc agcaactaaa
    29161 tcttcactca aatcatgtcg agcatgattg taaagatctt ttataaggct ttctaggttt
    29221 ggttctgcca tccctaccac ctcccttatg gtttaataat gtttaatcaa atcaaccgtt
    29281 gaacgatcca atttcttcac caaggcttgt aagaaagctt gcgcttctag gaagtcatcc
    29341 attgcataga gggtttggtg agaatggata taacgagcgc agacaccgat agttgttgat
    29401 gggacaccac catttttcag atgagctgca cctgcatctg ttccgccttt accacagtag
    29461 tattggtact tgataccagc ttcttcagcc gttgtcaaaa ggaaatcctt catccctggg
    29521 agaagcaagt gacctggatc atagaaacga atcaaggttc catctccaat cttgccttga
    29581 ccaccgtaga catcacctgc tggtgagcaa tcaactgcga ggaagacttc tgggtcaaac
    29641 ttggttgtag aggtatgagc gccacgcaga ccaacttctt cttggacgtt agaacccaga
    29701 tagagttcat tgccgagttt ttgacctaat aaagcttcag ctagctcgct taccatgagg
    29761 acaccgtagc ggttatccca agcttttgag atgatatttt tttcattggc tgtcaaaatt
    29821 gcagaactat ctggtacgat ggtatcacca ggacggatgc caaaactttc tgcctcagcc
    29881 ttgtccgcaa aaccaccatc aaaaacgata tcggcaatgg ctggcatggt tggtcccccc
    29941 tttccacgag tcaaatgcgg aggaacagaa cctgaaatca caggaatttc atgaccatca
    30001 cgagtcaaga gtttgaaacg ttggctgcta accaccatgg ggttccagcc accgatttct
    30061 acgacacgga aggtaccatc tggcttgatt tcgctgacca taaaaccaac ttcgtccata
    30121 tgagaagcga ccaagacgcg cggtgcatcc acagcttctg aatgtttgat accaaaaata
    30181 ccacccaagc catctgtcac cacttcatcc acatgcggtg tcaacttttc acgaagataa
    30241 gcacggacag gcgcttcatg acctgagact gcagcaagtt ctgttacttc tttaattttt
    30301 gaaaataatg ttgtcatttc agttccttct ttctttcatc cattttacca ctttttatag
    30361 gagaaggata gtgggaaggt ggatttctaa gttagtatct tagtcctgct ctatcttaga
    30421 aaaggatagt attctcttgc atgtagtgca aaatctagta aacattccaa aattaactcg
    30481 aatatttatt tccaaacaaa aaaacaatac accatcaaag ttgtttggat ttttcatgaa
    30541 atttacagaa aatagttgac ttccctttct tctttcttta aatatatagt tggttgagtt
    30601 tggaatagta cgctgtagct gctaaaacat ttctagaaat taatttgact tttctaatag
    30661 agttgttcat atcttatttc aatttactat agtacaaaac tagaaaagga aaaaatcatg
    30721 accaaaacaa ttcttgttac aggtgggact agctacattg gctcccatac cgttaaagct
    30781 cttttaaatg ctggctatca ggtgcatgtc ctcgataatc tctccacagg aaatcgagcg
    30841 gctgtggata gtcgtgctag ctttaaagaa ctggatgttt atgatgctag cgccttaaag
    30901 gcttacttag aagaaaatca gattgatgct gtcctccatt gtgcaggtga aattgttgtg
    30961 agcgaaagta ttgaaaatcc aagtaaatac ttcactgcca acgttgctgg tatggaccaa
    31021 gttctcaaag tcttatctga agttggcatt caaaaaatca tgttctcttc gactgcttct
    31081 ctctatggaa ataactgtat tgacaagccg gtgactgaag ataccctgct cgaccctgtc
    31141 aacccttatg cagagacaaa actgatgggc gaacgaatga tttactggat ggccaatcgc
    31201 tacgactgga aatatgttat tttccgttac tttaatgttg ctggggctga aatggatgct
    31261 tcaaacggtc tgcgtgtgaa aaatccaact cacatcattc caaatatcaa caagaccgca
    31321 ttgggacaac atgatagctt aaaaatattt ggagatgact acgatacacg tgacggttca
    31381 tgtattcgag attacattta tgtcttggac cttgcatagg ctcatgttaa aggaatgaac
    31441 tacctatttc aagaagacag ttcttctcaa atctttaact taggaactaa aaaaggctat
    31501 actatcaaag aaatctttaa aactgctgaa gaattactaa attaaaaaat cccacacgag
    31561 attgttgctc gacgtgctag tgacccagcc agtgtcctag cagatgcttc aaaagctaaa
    31621 caatatcttg attggacggc tagctactcc ctcgaagata ttattttatc agattaaggt
    31681 aaaaacattt tagaatagga taacaaagga gaaagtcttg ttgctctctc cttgttgtat
    31741 ttattaaatt gtcagaaatt ttattgacag attagaaaaa taatgttaca tttatatccg
    31801 caggtatctt tcgataccaa atctacatga aaggacgggg tatgaaactt tctcattatt
    31861 taattggctt acttctactc ctagtctttc tctctattag cattgggacc agtgattttt
    31921 catggggaaa gctatttgat ttcgaccagc agacctggct cctctttcaa gagtcccgtc
    31981 tcccaagaac tatcagtatt ctcctgactg cctctagtat gagtatggca ggccttctca
    32041 tgcagactat tacccaaaat cagtttgctg caccgagtac agttggaacg actgaagccg
    32101 ccaaactggg aatggtgctg agcctttttg tctttccatc ggctagtctg acccaaaaga
    32161 tgctcttcgc ttttatttca tccatcgtat tcaccctctt cttcctagcc tttatgacca
    32221 tttttactgt aaaggaaagg tggatgttgc ctctgattgg gatcatctat agcgggatta
    32281 tcggctcagt cacagaagtt atcgcctatc gtttcaatct ggttcagagt atgactgcct
    32341 ggacccaggg ctccttctcc atgattcaga cccatcagta tgagtggctc ttcttaggcc
    32401 tcatcatcct gataaccgtt tggaaattat cccaaacctt caccatcatg aatctaggga
    32461 aagaaaccag cgagagtttg gggatttcct actccctact tgaaaaactg gccctctttc
    32521 tggtggcgct aacgacaagc gtcaccatga ttaccgtggg tggcttacca tttctcggag
    32581 ttatcgttcc caatcttgtt cgcaagcgct atggagataa tctaagtcaa accaaactca
    32641 tggtcgcact ggttggtgcc aatctagttc tggcttgcga tatcctatcc cgagttctga
    32701 ttaggcccta tgagttgtct gtcagtctct tgctaggaat catcggtagt ctcgtcttta
    32761 tcctacttct ctggagaggg ggacgaaaag atgcagacta aaagcaaaca taccaagctc
    32821 ttctggattc tcattattct tgccatcgga gcttgtcttc tctacttttg gcccatcact
    32881 cacttgtcag cctttgcttg gaagttgcgt tcccaaaaga tcatcgttta tctcttggta
    32941 gccatcgcga ctgggatttc gaccattagt tttcaaaccc tgacggaaaa tcgcttcctg
    33001 acgcctagta ttttgggaat tgaatccttc tacgtcctac tacaaaccct actactggtt
    33061 tttgaaagca agtttcttca acttggcaaa tcccctatct tagaattcct agtcttactt
    33121 cttgtccagt ccctcttctt tctcgcctta caaggttact tgaagacact gatgaagcaa
    33181 gacctggtct tcatcctgct gatctgtcta gcgctcagaa gtctctttcg aaatatcagc
    33241 accttccttc aagtcctaat ggatccaaac gaatacgata aactgcaaaa tagtcttttt
    33301 gcctcctttc aacatcttaa cacttccatc ctagccatcg gttctctgat catcctcgct
    33361 ttgacaatct ttttctttcg aaaagcagtc gttctagatg tcttgcacct gcaaagagaa
    33421 acggctcaga tattgggact cgatgttgaa aaagaacaga aagagctcct ctggggaatc
    33481 gtgcttttga cctcaacggc cactgccttg gtaggaccta tggccttctt cggctttatg
    33541 ctggccaacc tcacctacct gattgtcaaa gactatcagc acaagttact ctttatagtg
    33601 gccattctgg ttggatttat tagcttaacc ttggggcaag ccttgattga acgagtcttt
    33661 gcactggaaa ttcgtatcag tatgatcatt gagagtgtgg gtggcttctt attctttatc
    33721 ttactatata ggagggctcg tcagtgaaac tggaaaacat tgacaaatcc attcaaaaac
    33781 aggatatttt gcaaggcatt tcgcttgaag tcagtcctca aaaactgaca gcctttattg
    33841 gtccaaatgg tgctggaaaa tcgactctcc tctccatcat gagcagacta accaagaaag
    33901 atcagggagt tctcagtatc aaaggacgtg aaatcgagag ctggaattcg caagaactgg
    33961 cccaagaact aaccatccta aaacagaaaa tcaattacca agccaaattg actgttgaag
    34021 aactggtcag ttttggacgt tttccctaca gccgaggtcg acttagatca gaagactggg
    34081 aaaaaatccg agaaactctg aactatttgg aactgaccaa cttaaaagac cgctacatca
    34141 atagcctgtc aggggggcaa ctccagcgcg tctttatcgc tatggtactg gcccaggata
    34201 cggactttat cttgctggac gaaccactca acaatctcga tatcaagcaa agcgtcagca
    34261 tgatgcagat tcttcgacga ctggtggagg aactcggcaa gaccattatc atcgtcctcc
    34321 acgatatcaa catggccagt cagtatgcag atgaaattgt cgccttcaag gacggccagg
    34381 tctttagcaa gggaagaacc gatcaaatca tgcaggctga cctgctcagt caactttatg
    34441 agattcccat cacgctagct gatatcaata acaaaaagat ctgtatctat agctagtaac
    34501 ataaaagctc aagttagaga accttcagtc tcttagtcaa taagattaag agactcccta
    34561 aatcgttatc acattttaaa aaggagaaat tatgaaaaca tcccttaaac tttatttcac
    34621 tgccctagtg gccagcttct tgctcctact tggtgcatgt agtacaaact caagcactag
    34681 tcagacagag accagtagct ctgctccaac agaggtaacc attaaaagtt cactggacga
    34741 ggtcaaactt tccaaagttc ctgaaaagat tgtgaccttt gacctcggcg ctgcggatac
    34801 tattcgcgct ttaggatttg aaaaaaatat cgtcggaatg cctacaaaaa ctgttccgac
    34861 ttatctaaaa gacctagtgg gaactgtcaa aaatgttggt tctatgaaag aacctgattt
    34921 agaagctatc gccgcccttg agcctgattt gattatcgct tcaccacgta cacaaaaatt
    34981 tgtagacaaa ttcaaagaaa tcgccccaac cgttctcttc caagcaagca aggatgacta
    35041 ctggacttct accaaggcta atatcgaatc cttagcaagt gccttcggcg aaactagtac
    35101 acaaaaagcc aaggaagaat tggccaagct agacaagagc atccaagaag tcgctactaa
    35161 aaatgaaagc tctgacaaaa aagcccttgc gatcctcctt aatgaaggaa aaatggcagc
    35221 ctttggtgcc aaatctcgtt tctctttctt gtaccaaacc ttgaaattca aaccaactga
    35281 tacaaaattt gaagactcac gccacggaca agaagtcagc tttgaaagtg tcaaagaaat
    35341 caaccctgac atcctctttg tcatcaaccg tacccttgcc atcggtgggg acaactctag
    35401 caacgacggt gtcctagaaa atgcccttat cgctgaaaca cctgctgcta aaaatggtaa
    35461 gattatccaa ctaacaccag acctctggta tctaagcgga ggcggacttg aatcaacaaa
    35521 actcatgatt gaagacatac aaaaagcttt gaaataagcc acttcaaact caatttaata
    35581 ctcaatgaaa atcaaagagc aaactaggaa actagccgca ggttgctcaa aacactgttt
    35641 tgaggttgca gatgaaagct gatgcggttt gaagagattt tcgaagagta taaaattttg
    35701 acattctaaa acgcatccta tcaagttcac tcaaacctga taggatgcgt ttttatcatt
    35761 ttgaaatcta tttaccccac ctcattcccc ttcttgattt cgtttaaggg aaaagtggtc
    35821 tggaacgggg tccttacctg ttttcgacca gggatgacaa cgtaaaatcc gagccaagcc
    35881 catcaatacc cccttaaaac catgtttttc aatagcctga atcatgtagt tggaacaagt
    35941 cagctcaaag cgacaagagg gtggaaagac tggtgagata aaacgttggt aaaagcgcac
    36001 aagcgctatt aaaattcgtt tcattatttc ttagttacag ccatggtgtg tagttggctg
    36061 atttcttttt tattaagacg acgggattct cctggacgga gtcctgtcaa gtctaggtgt
    36121 ccgaaacgag tccgagacaa cttatctact tggagaccaa cagcttcaaa catcttttta
    36181 acctgatggt tacgcccttc atggatggtc aactgcacca cagagcgatt tttgactggg
    36241 tccactttga gaatttcata aacagctggc ttggttttct taccatcaat ctcaagacca
    36301 cgggtcaagg ggcgaagatt gtccttattg gccacacctt taacacgcgc gacataaacc
    36361 ttgtcaatct cattacgagg gtgaatcatc tcgtctgtaa agtccccatc attggtcaaa
    36421 atcaagactc ctgatgtatc ccagtccaaa cgacccacag ggtaaatgcg ctctttgaca
    36481 ttgggcaaga ggtcgacaac cgtcttgcga cccttgtcat ctgttacact ggaaatgaca
    36541 ccgcgtggtt tgttaagcag ataatagacc ttttcttcgt tgtagatagg ttgaccttca
    36601 acttcgacct tgtcgcctga cttgatagtg gttgctagtt cacgcaccac ttggccgtta
    36661 actgtcacca aaccttgctt gatcagctct tctgcttttc tcctactggc cacacctgcg
    36721 tgggcaatat acttattgat tctcatcttc ttctatcctt tcaccaaata attggctttc
    36781 ttgggcttga atctcaagct catcaatcac tggtaattct tctaaatggt ttatccccat
    36841 gtaatctagg aaataatccg tagtcacata gaggttgggg cgccccaata cttccttttt
    36901 cccgtcttcc tttatcaggt ccaaagcttg caactttgcc aaggctccac tcgagttaac
    36961 cccacggatg gcatcaattt ctatccgcgt aatcggctgt ttgtaggcaa taatggacaa
    37021 ggtctcaagg gcagcccgag acaagctctg gttgataggc gccttagagt attccttcaa
    37081 aatctctgca aattgaggct tggtcaccaa tctataagca ccacttgtct caatcaaagc
    37141 caaactggaa tctgggtcct tttcatactt ctgggctaat tttcctaaac tttgctggat
    37201 gcctgtcggt ggcagagaga ggagttcagc taactggcgg acccgaatcc catcttcacc
    37261 cgctacaaac aagagcgctt ctatttttgc taaagtactc atctttcctc tctatcaagt
    37321 ctagctttga ggcacttgac tttcttcctt cttttccatg agatagatat ctccaaaact
    37381 ctcctcttgc acgaggatca gctcctgggt tttgattaac tctagggttg ccaaaaagag
    37441 ggtgatgacc tcttggacat tctgggcttc cttgaacaaa tcctgcaagc gcaattgatc
    37501 tcgtccaatc aaggattctt tcacaataat catcatgtcc tcaatcttat actcatcccg
    37561 caagatagtc gtgtgatttt gtgcaaactc ctcttttttc ttggctagga tatttgaaaa
    37621 agccaaaaag aggtcaatgg tcgtcttgtc atgcacaagc tccgcatctt cgtaaatcaa
    37681 ctctgtcggc gctttggaat aatactgggc ccgttcttgg tgcttggctt ccaagtgctc
    37741 acccaagagc ttgaacttgc gatattcttc gatttgagag aggaggtcct gctccaggtc
    37801 atcccccaag tctgtcactt ctgctacctt cggaaggagt ttacgactct taatcagcat
    37861 gagctgacta gccatgacca tgtactcacc cgtcacttcc agacgcatgg cctgcagggt
    37921 tgagacatag gctagatact gttcgatgac ttccgtaatg ggcacatcgt agatatccat
    37981 ctggtactta gaaaccagat gcaagagtaa gtccaggggt ccttcaaaat cttttaattt
    38041 aatatccatt atctatattt ttctaaggtc aggactgttt ttaatcctaa tttttttgca
    38101 atttcgtaca aatcgacctt gttttctatt tgtcttagaa taaactgttc acgtaagact
    38161 tgagctgata aggatggaaa acctttctcc ttgacaaaag attctaactg acgaaaggcc
    38221 cactgacgag aatagggttt ccctcctctt tcaaaaagat aggtctgccc catcaagggt
    38281 tccaattctg aaagcaaggc cgtgggaatg gtgacaatcc tccgttggga agccttgctg
    38341 attcgcaaca cctgaaaatc cagattgatg tccgcaacct tgatggctaa aatctcactg
    38401 ggcaagagcc ccatttctag gattaagagc gctagcaagc ggccctctgg atggtcgctt
    38461 tcctgccaaa aagagtctag gtatagaatc tctggctttt ccgtcttctt ttcagcttgt
    38521 ttggctaatt ccaagcggta aaagctgtcc acctctcctt tttgatagag aaagtataga
    38581 aattggttac aggccgaaat ctttcgcttc tgggcgctga tttttagatt ggctagctgg
    38641 gcttggtaaa tcttgagact ggtctcagaa atccgctcac ctaccatgtc taaaaattgc
    38701 tccaaatcat acttatagga ctgcttggaa ttgacagaca agccctgctt ttcctctaaa
    38761 aaggctgaaa tcctgtctct cattggcatc gaatctcata ttccttacta aagtcatgca
    38821 agagggcatt aacggccttg aggatggact tgcgcgtaat aatcccttgg aaaataccct
    38881 ctgcatccac aaccggtaag aaggactcat ctactagctt gtgcaagacc tccgtaatgg
    38941 tgaaatcagg cgaaacaacc gctacgtccg tttttgtcat atgaacgata tccgtatccg
    39001 ccatgatttc ttggctcaag tcatgctcca tctgataagc cataatatct ctgagtccaa
    39061 tcgtcccaac aaactgtttt tcatctgtca caacgggaac acgggtatag gtcatctgac
    39121 tgagcaagag ggtcgcatga tccgcattgt gagtatcaat caacacagct agatttttag
    39181 caggggtcaa aaaagtttcc tcctgcccca acaagaaagt ctcaaactcc ttggcaatca
    39241 tcggctaaac tccttggaca aacctggata cacctcgtga tctcgtgtca aaaagtccac
    39301 tttgaagtaa ctatcatcaa tctccacacg agcatagaga cattctctga tggtacctcg
    39361 tggttgactg atagagcctg gatttagaaa gaggatcttg ccttccaacc aagcacttgg
    39421 cacatgcaag tgaccataga ggcagatagc ggcctcttcc tcctgagccc agtagtccaa
    39481 cttttgaaag ttgaaattga tgtcaaacaa gtgaccatga gtttggataa tcttggtcga
    39541 accaagctca gtcaccagac gttctgggta gccggcgtag aagtccatgt tccctttaac
    39601 aacgcggatg ccctcccaaa gtggagaatc cggacgtagt tcagaatcgc cgttatgaaa
    39661 aacggcatcg actttgccca catagcgatc acggacttct tccacaatca agctatcgcc
    39721 atgggaatcg ctcattacaa tgatggtttg ctttgccatg atggaaatac ctccaaaagt
    39781 ttcttaacgg ctaaggcacg gtgagattga ctattttttt cttccagggt taattcagct
    39841 gatgactcac ctgtctctcc tacaaggaag aggggatcat agccaaagcc attttcaccc
    39901 ttaggttcaa agttaatata acctgaccag tctgcttcaa caactaaact ttccttattt
    39961 gggctggcta cgactagggt tgtgtggaac tgagccgagc ggtccttgag ttcaaagacc
    40021 atggccaatt cgtgcaagag tttggcatta ttttcacggt cagttgctcc cacacctgcg
    40081 aaacgagctg accagacgcc tggtaagcca ccaaggacat cgactttgag accagaatca
    40141 tctgccaaaa ccatcttgcc cgttaattga gaaatggttt ctgccttaag gcgggcattt
    40201 tcctcaaagg tcatacctgt ttctgctact tcaggcaggt cagggtagtc attaagattt
    40261 tccacatcgt agcctaactt atcaaagata gctcggaatt ccttggtttt accttcgtta
    40321 cgagtcgcaa tcaacaaggt ttctctgact ttgcttgtct caaagaaatc atgaacattg
    40381 accccttctt taggcaattc tacatacaag agttgcccat tttcaaccaa gagcagggcc
    40441 ccatgacgtt gaataacttc caagtttcgt cccatttctt gattaagcat atctaccaca
    40501 aaggagaaca aacggtaggt agaaccatag cgtaaaacag taactgaaag cgggaaacca
    40561 tactcttcat ctccaaatat tttggagaat tcaaacagag gaaaatctgt ctgatagtcg
    40621 ctcaaactgt taacgccacc aaaaatacta taagacccaa cataccagtc ctggtcatcc
    40681 ttatattcat aaattttatt tgtcataatt ctacatgctc cacatgaatc tctttttcca
    40741 gccattcttc accaatttgt gcaaaacttt ggctactggc tgttgtgtaa aaacggtgat
    40801 ggagtggtcc agcatcgcga ccacgattga tttcaaaata attgagtaag actgagatat
    40861 cccgtacgca ctctgcccca ctatcgatga gctgaacctt tggccccatc acattttgga
    40921 taatagggcg aaggagtgga taatgagtac agcccaaaat caggctatcc acctttccaa
    40981 ccaagggacg cagggtttca tagaccacct tcttggtaac actggttgac agggcacctg
    41041 actcaaccaa gggagcaaac ttgggacagg ccaagctctc cacctgtaag tcgggatcca
    41101 gatcatggat tttctgacgg tatatgtctg attgtaccgt catgggcgtt ccaatcactc
    41161 cgattttccc accttgactg gacttgatgg ctgccgaagc tcctggcaaa attacaccca
    41221 agacaggaat atctagttga gccttgattt cttcccagac gaccgcagtc gcagtgttac
    41281 aagcaatgac aatcattttg acatccttgg tcaagagaaa gttgaccagc tgccaagtat
    41341 attcacgaat ttgctcagca ggacgggggc catagggcgc ccgcgccgaa tctccaatat
    41401 agacgatttc ttcatgggga agctggcgca tgagctcgcg cacaacggtc aagcccccga
    41461 cacccgaatc caaaaaacca attggtcgat tatccataca gtcttctttc tagtcttttt
    41521 tctgattgat cgttcattat gattccttgt actgaacgaa ctgaccgaca gcttgataga
    41581 atgtcaacta cctctctctt aatcataatc aaatatcaat agaatgcaag gaaaaagtct
    41641 catccctaaa ccataaccaa catagtgaga agtctggaac tttcatccca gacttttcct
    41701 tatttatttt ttctttttat tgttagcaag ggctgccttt tgttggcgga tgatttggtg
    41761 gtaaacttgt tgtaccttag cttcgcttgg tttttgacca tttgcactca aaagagtacg
    41821 aactgcttca gcattcaaac gtgggttgtc agcaaattct ttttcgattt gcttacgaac
    41881 caagtacatt cctccaagag ctcctcctag aaaagctagc acaatcaata caattgctaa
    41941 aagtaaatcc atcatttttc tcctgtttct ttttgaatcc ctttcattat accacaaact
    42001 agccaccctg accagtttgt tctacacttt cagggatgga atagacagca aaaagaaccc
    42061 tgcttttctg aaaaagaggt ctccttgcta agtttatact caatgaaaat caaagagcaa
    42121 actaggaagc tagccacagg ttgctcaaag caccgctttg aggttgcaga taaaactgac
    42181 acggtttgaa gagattttcg aagagtatta atttacataa atagccagtg tttgataggg
    42241 tttgagtaga attttctcag acacttctgc atcttcatag tttgatatca aaatctgtcc
    42301 attttggtag actgctggca agtcgatttc cacttcttta gcataaaagt tattgagcac
    42361 tagtaacttt tgatcctcaa actggcgttc aaaagcgtag acttgtttgc tatcttcaaa
    42421 ggctggtttg taacttcctt ctgaaatgat tggcatttcc ttacgcagtc gaatcaagtc
    42481 ttgatagaag gtgaaaatcg gaccctggat ttcattttct acattgatgt atttatagga
    42541 tttaccagct ttcaaccatg gagtgcctgt tgaaaatcct gcattttccg aagcatccca
    42601 ctgcatggga atgcgtgaat tatcacgcga cttagcttga ataatctgga aggcttcttg
    42661 ctgactcttt ccttcttcta agagcgtctg ataggcatta agcgattcga catccacata
    42721 atcagccata gaatcatagt ctgggtcaat catcccgatt tcttcaccca tatagatata
    42781 aggtgtccca cgtgacaggt gaatgctagc cgctagcatg gtggctcctt ccttgcggaa
    42841 gttttgaata tcgacaaaac ggttcaaggc acgtggttga tcgtgattgt tccaaaagag
    42901 ggcactccaa ccgtctttat cactcatttc cttaccccaa ctatggtaaa gactcttcaa
    42961 ctcttcaaaa tcaaagggag ccaaggtcca cttttgtcca tccttatagt ccaccttgag
    43021 gtgatgaaaa ttaaaggtca tggataattc ctgacgatca ggcgacgaat agaggacaca
    43081 gttttccatg gtggtagaag acatttcccc aactgtcata aagctatcgt cagatccaaa
    43141 agtggcttgg ttcatcatac gcaaatagtt atgaacgatg ggtttgtctg tataagctgg
    43201 cttcccttca ttttcaggac agtccactga aacctcgtcc ttaccgatca aattgatcac
    43261 atcaaatcgg aaacctttga tacccttgtc gcgccagaaa ttaacaacct tgaaaagctc
    43321 cttacggaca ttggaattgc gccagttaag gtcagcctgg gtctcatcaa ataggtgaag
    43381 atagtatttc ccagtatccc cgaaaggcgt ccatgcagaa ccaccaaact tagactgcca
    43441 atctgttggt tggtcttgga tgaagaaaaa gtcttgataa tacttatcac cagctagggc
    43501 tttctgaaac cattcatgct ctgtcgaaca atgattaagt accatgtcca gcataaagtc
    43561 aatcttgtgc tctttaccga cacacaccat ttcctcaaaa tcagccatat caccaaaaag
    43621 aggatccact gccatataat ctgaaatatc gtaaccatta tcccgttgag ggcttggata
    43681 gaatggattg agccagacca tatccacacc tagtttggct aaatagggaa ttttttcgat
    43741 aatcccacgg aaatccccaa taccgttttc agtggtgtct ttgtaagatt ttggatagat
    43801 ttgatagact acttttcctt tatcaagtgt catctgtttc tccttttctg ataaaaggga
    43861 ggaagcagtc ttccgtccct atttgtgcta tttcaattat actcaatgaa aatcaaagaa
    43921 caaactagga agctagccac aggttgctca aaacactatt ttgaggttgc agatagagct
    43981 gacgtggttt gaagagattt tcgaagagta ttagattcgt gtagcgacca tgagagatgc
    44041 tccagcttgg atcgttgtcg gataagttcc gggaatagtc gctgtataag catcttggtt
    44101 ggtgatgata acaggagttt ctgtcaccag acctgcagcc ttaatgacat ccatatcaaa
    44161 acgaatcagt tgctgaccaa ctgtaacgtg atctccttgg actacaagac tttcaaaacc
    44221 tttgccatca agacctactg tatccatacc gatgtggatg agcaattcaa ctccctcgtc
    44281 agagacaatg ccgatggcat gcttggtagg gaaaagaacc gtcactgtcc cattaactgg
    44341 agaggtcaac tcaccttggc ttggttcaat gactagacct tgccccatga cacctgatgc
    44401 aaaaatagga tccgtcgctt gactcaattc tttcacttgg ccagttagtg ggctgataat
    44461 ttctaccgaa gtaagttcta ctggttcatg gttcacaaat tctgcttctt cttgagcaac
    44521 gaattctgcc tgcaagttcg tatcgccctc tgtttttgta aagagaccag ccttgcggaa
    44581 gaagaaagtc aagagcattg gaacaacaat cgcaactagc atagttcctg caaatggcag
    44641 catgtattga ggttgaatag agagaatacc tggcaaacca ccgataccaa tagaagccgc
    44701 agttacatta aaagtaacgg ataacatgcc tgcaagggct gaaccagtca tcccagcaac
    44761 aaatggataa atatatttta cgttaacccc aaaaagagct ggttctgtaa caccgagata
    44821 ggctgaaatg gttgcaggaa gtgaaacctg agcctcacgc tcatcatggc gatgcatgaa
    44881 ataatagaca aacacggctg agccttgagc aatattagaa agagcaatca ttggccatag
    44941 ggcagtgcca ccagcatccg caatcaattg tgtatcaatg gcattggtca tatggtgcag
    45001 acctgtgatg acaaatggag cgtagagggc accaaaaatt gcaccgaaga gccatttaac
    45061 tggaccagtt aaacctgcca agacaactga tgaaagtcct tgtccaattg tccaaccgat
    45121 tggtcccaaa acagtatgag ccaaaatcaa ggctggaatc aatgacaaga aaggtacaaa
    45181 aatcatagaa atgacttctg ggatatgctt gcgccagaag atttcaagat aagacagact
    45241 caaacctgca agcaaggctg ggataacttg ggcttggtaa ccgatacgat taacagtaaa
    45301 atagccaaaa ttccaaaccc agtttgccgc gatatcagct gctggcgttg aagcaaccgc
    45361 ataggcattg agcaactgag gcgataccaa acagattccg agaacaattc ccaaaatttg
    45421 gctggttccc atcttacgag aaacagacca agtaatccct actggtaaga actggaagat
    45481 agcttcacca ggcaaccaga ggaagtgatt gacacctgcc caaaactgag aggattctgt
    45541 gatggtcttg ccatccaaca tcgaccaatg gacaccttcc aagacattac ggaaaccgag
    45601 gatcaatcct ccgactatca aggctggaat aatcggagta aaaatctccg ccagagtggt
    45661 cataacacgt tggaccacgt tttgattact cttagctgca gacttggctg cttctttgga
    45721 aacaccctca atacctgaaa cggctgtaaa atcattataa aagatgggca cgtcatttcc
    45781 aatgattacc tgaaattgac ctgcatttgt aaaagttcct ttaacagctg gaattgactc
    45841 gatagcttta acattagcct tcttatcatc tcctaaaaca aagcgcatcc gtgtcgcaca
    45901 gtgggtgacg gcagtcacat tttctttgcc tccaattgcc tgaagcagat ctttggcttc
    45961 ttgttcaaat tttcccattt gattctcctt atacttgtca aagcaagttt gatttgataa
    46021 gtatattgta aacgatacca aacttgtctg caacttgttt ggtataaaaa gggtgttttt
    46081 ttgtaaattt tctagcactt gtatggtaaa atagatacag gtgttcatta aactagacta
    46141 aaaacctatt taagcaggca aaatgaagaa ataccaacaa ttatttaagc aaatccaaga
    46201 aaccattcaa aacgagactt acgctgtcgg agatttcctt cctagcgagc acgaccttat
    46261 ggagcaatat caagtgagtc gtgataccgt ccgaaaggcc ctgtctctcc tccaagagga
    46321 aggattgatc aaaaagataa gagggcaagg ttctcaagtc gtcaaagaag aaaccgtcaa
    46381 tttccctgta tccaacctaa ccagctacca agaactagtt aaagaacttg gactgcgctc
    46441 taaaaccaac gtggtcagtc tggacaagat tattattgat aaaaaatcct cactgataac
    46501 cggtttccca gagtttcgga tggtttggaa ggtggtccgc cagcgtgtgg tggatgatct
    46561 ggtatccgtt ctggatacag actatctgga tatggaacta attccaaatc tcactcgcca
    46621 aattgctgag cagtctatct attcttatat agaaaatggc ctcaaactcc ttattgatta
    46681 tgctcagaag gaaatcacca ttgaccactc aagcgaccga gacaagattc tcatggacat
    46741 tggcaaagac ccttatgtcg tttcgattaa atcaaaagtc tatctccaag acggacgcca
    46801 atttcagttt accgaaagtc gccataagtt agaaaaattt agatttgtag attttgcaaa
    46861 acgcaagaaa taaaagactg agacaccaga tctcagcctt tttcggctct ataatatttg
    46921 tagtgggtaa cccccctatg gatattatgg agcctatttt gtgtagaaaa aaagtcccat
    46981 atgacctata atgaaaagcg acaaaacaac tcattagaaa gaatcatatg gaacaattac
    47041 attttatcac aaaattacta gacattaaag accctaatat ccagatttta gacatcatca
    47101 agaaggatac acacaaggaa atcatcgcca aactggacta tgaagctcca tcttgtcctg
    47161 agtgcggaag tcaaatgaag aaatattact ttcaaaaacc ttctaaaatt ccttatcttg
    47221 aaacaactgg tatgcctact agaattctcc ttagaaagcg tcgtttcaag tgctatcatt
    47281 gttctaaaat tatggttgct gaaacttcta tcgtcaagaa gaatcaccaa atccctcgta
    47341 tcatcaacca aaagattgct caaaagttaa ttgaaaagat ttctatgact gatattgccc
    47401 atcagctttc catctcaact tcaactgtca ttcgaaagct caatgacttc cactttgagt
    47461 gtaattttag aaatctgcct aagattatgt cttgggacgt tgaaacagtc cggggagtg
//
LOCUS       DAVKMJ010000013        46695 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000013 DAVKMJ010000000
VERSION     DAVKMJ010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 46695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46695
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.013"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..971)
                     /locus_tag="VW348_000726"
     CDS             complement(<1..971)
                     /locus_tag="VW348_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEU9745664.1"
                     /translation="MEQLHFITKLLDIKDPNIQILDIIKKDTHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYA
                     FTKGKMSFIAQDFNNLNIITVLKGRTQAVIRNHFLKYDRAVRCRVKIITMDMFSPYYD
                     LARQLFPCAKIVLDRFHIVQHLSRAMSRVRVQIMNQFHRKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRMHLTNKEILDKLLSYSQDLKHHYQLYQLLLFHF"
     gene            complement(1247..3352)
                     /locus_tag="VW348_000727"
     CDS             complement(1247..3352)
                     /locus_tag="VW348_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU9745665.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSQLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     TKHLEADMEDGVLVIREKA"
     gene            complement(3633..3821)
                     /locus_tag="VW348_000728"
     CDS             complement(3633..3821)
                     /locus_tag="VW348_000728"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745666.1"
                     /translation="MLEIDLTVLIDLSCSYFVLIYSFEMVDRTDEVSSKHGFEVVDKE
                     KLMWFEEVFEECKKILVS"
     gene            complement(3961..4941)
                     /locus_tag="VW348_000729"
     CDS             complement(3961..4941)
                     /locus_tag="VW348_000729"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEU9745667.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            complement(4943..7195)
                     /gene="pbpX"
                     /locus_tag="VW348_000730"
     CDS             complement(4943..7195)
                     /gene="pbpX"
                     /locus_tag="VW348_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HEU9745668.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            complement(7199..7516)
                     /gene="ftsL"
                     /locus_tag="VW348_000731"
     CDS             complement(7199..7516)
                     /gene="ftsL"
                     /locus_tag="VW348_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEU9745669.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(7528..8478)
                     /gene="rsmH"
                     /locus_tag="VW348_000732"
     CDS             complement(7528..8478)
                     /gene="rsmH"
                     /locus_tag="VW348_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEU9745670.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNNYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            8644..8838
                     /locus_tag="VW348_000733"
     CDS             8644..8838
                     /locus_tag="VW348_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9745671.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            8854..9396
                     /locus_tag="VW348_000734"
     CDS             8854..9396
                     /locus_tag="VW348_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEU9745672.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNIIPLLLAYKYPQEVALIYPPLILVIALIASGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            9407..9649
                     /locus_tag="VW348_000735"
     CDS             9407..9649
                     /locus_tag="VW348_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745673.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            9660..9995
                     /locus_tag="VW348_000736"
     CDS             9660..9995
                     /locus_tag="VW348_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745674.1"
                     /translation="MKSLARLLIIHVFISIFLFFALTSGAISHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(10105..11106)
                     /locus_tag="VW348_000737"
     CDS             complement(10105..11106)
                     /locus_tag="VW348_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9745675.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(11166..13067)
                     /locus_tag="VW348_000738"
     CDS             complement(11166..13067)
                     /locus_tag="VW348_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEU9745676.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHYSKDYEKVKRSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKSYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIRVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(13089..13382)
                     /locus_tag="VW348_000739"
     CDS             complement(13089..13382)
                     /locus_tag="VW348_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEU9745677.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            complement(13382..14200)
                     /locus_tag="VW348_000740"
     CDS             complement(13382..14200)
                     /locus_tag="VW348_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEU9745678.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            complement(14187..14966)
                     /locus_tag="VW348_000741"
     CDS             complement(14187..14966)
                     /locus_tag="VW348_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEU9745679.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            complement(14981..15472)
                     /locus_tag="VW348_000742"
     CDS             complement(14981..15472)
                     /locus_tag="VW348_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEU9745680.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            complement(15483..16673)
                     /locus_tag="VW348_000743"
     CDS             complement(15483..16673)
                     /locus_tag="VW348_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="unsaturated chondroitin disaccharide hydrolase"
                     /protein_id="HEU9745681.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(16685..17119)
                     /locus_tag="VW348_000744"
     CDS             complement(16685..17119)
                     /locus_tag="VW348_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9745682.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            17393..18208
                     /locus_tag="VW348_000745"
     CDS             17393..18208
                     /locus_tag="VW348_000745"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEU9745683.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            18227..18868
                     /locus_tag="VW348_000746"
     CDS             18227..18868
                     /locus_tag="VW348_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEU9745684.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            18899..19900
                     /locus_tag="VW348_000747"
     CDS             18899..19900
                     /locus_tag="VW348_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEU9745685.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            19910..20539
                     /locus_tag="VW348_000748"
     CDS             19910..20539
                     /locus_tag="VW348_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEU9745686.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(20918..21303)
                     /gene="tnpA"
                     /locus_tag="VW348_000749"
                     /pseudo
     CDS             complement(20918..21303)
                     /gene="tnpA"
                     /locus_tag="VW348_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(21656..24735)
                     /locus_tag="VW348_000750"
                     /pseudo
     CDS             complement(21656..24735)
                     /locus_tag="VW348_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
     gene            24958..25434
                     /locus_tag="VW348_000751"
     CDS             24958..25434
                     /locus_tag="VW348_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEU9745687.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            complement(25656..27869)
                     /locus_tag="VW348_000752"
     CDS             complement(25656..27869)
                     /locus_tag="VW348_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEU9745688.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSKTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAIPLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNKNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQVAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GILDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPMYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLAFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTI
                     PVFAKSGAIIPLVGSEIDMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELTLQGDSSIVPSNRRHRIHFKGTNVSIIELPNKNDTARFECKDNKTISLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(28270..28446)
                     /locus_tag="VW348_000753"
     CDS             complement(28270..28446)
                     /locus_tag="VW348_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745689.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            complement(28826..30172)
                     /gene="celB"
                     /locus_tag="VW348_000754"
     CDS             complement(28826..30172)
                     /gene="celB"
                     /locus_tag="VW348_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HEU9745690.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVIIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDVFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            complement(30252..30758)
                     /locus_tag="VW348_000755"
     CDS             complement(30252..30758)
                     /locus_tag="VW348_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745691.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQMLISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            complement(30789..31103)
                     /locus_tag="VW348_000756"
     CDS             complement(30789..31103)
                     /locus_tag="VW348_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HEU9745692.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            complement(31113..33092)
                     /locus_tag="VW348_000757"
     CDS             complement(31113..33092)
                     /locus_tag="VW348_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEU9745693.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFDQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNGFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSHVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFINIFEKIK"
     gene            complement(33210..33524)
                     /locus_tag="VW348_000758"
     CDS             complement(33210..33524)
                     /locus_tag="VW348_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HEU9745694.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            complement(33654..33892)
                     /locus_tag="VW348_000759"
                     /pseudo
     CDS             complement(33654..33892)
                     /locus_tag="VW348_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
     gene            complement(33944..35380)
                     /locus_tag="VW348_000760"
     CDS             complement(33944..35380)
                     /locus_tag="VW348_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEU9745695.1"
                     /translation="MTTFKDRFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITSGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPATCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKEVISSNGESVE"
     gene            complement(35570..35908)
                     /locus_tag="VW348_000761"
     CDS             complement(35570..35908)
                     /locus_tag="VW348_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HEU9745696.1"
                     /translation="MTLTIHVYYKGDGDSAIKFAREMLDSGLVEEIRNQKGNLKYEYF
                     LPIEKEGTILLIDQWINQETLDKHYQSKTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            complement(36064..36273)
                     /locus_tag="VW348_000762"
                     /pseudo
     CDS             complement(36064..36273)
                     /locus_tag="VW348_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(36583..36975)
                     /gene="rpsI"
                     /locus_tag="VW348_000763"
     CDS             complement(36583..36975)
                     /gene="rpsI"
                     /locus_tag="VW348_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEU9745697.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(36994..37440)
                     /gene="rplM"
                     /locus_tag="VW348_000764"
     CDS             complement(36994..37440)
                     /gene="rplM"
                     /locus_tag="VW348_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEU9745698.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISELI"
     gene            37797..38114
                     /locus_tag="VW348_000765"
     CDS             37797..38114
                     /locus_tag="VW348_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEU9745699.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            complement(38265..39077)
                     /gene="folK"
                     /locus_tag="VW348_000766"
     CDS             complement(38265..39077)
                     /gene="folK"
                     /locus_tag="VW348_000766"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEU9745700.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(39120..39674)
                     /gene="folE"
                     /locus_tag="VW348_000767"
     CDS             complement(39120..39674)
                     /gene="folE"
                     /locus_tag="VW348_000767"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEU9745701.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(39655..40977)
                     /locus_tag="VW348_000768"
     CDS             complement(39655..40977)
                     /locus_tag="VW348_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEU9745702.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLESIAEQKAGIIKQGMPLVTGRIAPEALAVIDRIAEEKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGCFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADH
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKARNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(40979..41923)
                     /gene="folP"
                     /locus_tag="VW348_000769"
     CDS             complement(40979..41923)
                     /gene="folP"
                     /locus_tag="VW348_000769"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEU9745703.1"
                     /translation="MSSKANHAKTAICGIINVTPDSFSDGGQFFALEQALQQARKLIA
                     EGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDTWKSQVAEAAL
                     AAGADLVNDITGLMGDEKMAHVVAEARAQVVIMFNPVMARPQHPSSLIFPHFGFGQTF
                     TEKELADFETLPIEELMEAFFERALARAAEAGIAPENILLDPGIGFGLTKKENLLLLR
                     DLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDTASAHVTSIAARQ
                     GVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(42048..42755)
                     /locus_tag="VW348_000770"
     CDS             complement(42048..42755)
                     /locus_tag="VW348_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9745704.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLMVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            complement(42808..44226)
                     /locus_tag="VW348_000771"
     CDS             complement(42808..44226)
                     /locus_tag="VW348_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEU9745705.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTKVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            44416..45228
                     /locus_tag="VW348_000772"
     CDS             44416..45228
                     /locus_tag="VW348_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9745706.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            45567..46586
                     /gene="adhP"
                     /locus_tag="VW348_000773"
     CDS             45567..46586
                     /gene="adhP"
                     /locus_tag="VW348_000773"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEU9745707.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSETMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
BASE COUNT        14069 a        10110 c         8085 g        14431 t
ORIGIN      
        1 tgaaagtgaa acagcaagag ttgatagagc tgatagtggt gtttcaagtc ttgtgaatag
       61 ctcaaaagct tgtctaaaat ctctttattg gttaagtgca tacgaaaagt aggacgataa
      121 aatcgcttat cactcagttt acggctatcc tgttgtatga gcttccagta gcgcttgata
      181 gccttgtatt catgggattt tcgatgaaac tgattcatga tttgaacacg cacacgactc
      241 atagcacggc taagatgttg tacaatgtga aagcgatcca acacgatttt agcacacggg
      301 aaaagttgtc tagctaaatc atagtaagga ctaaacatat ccatagtaat gattttgacg
      361 cgacatcgga cggctctatc atatttaaga aagtgatttc ggatgacagc ttgtgttctt
      421 cccttaagaa cagtgatgat attgagattg ttaaaatctt gcgcaatgaa gctcatcttt
      481 ccttttgtaa aagcatactc atcccaagac ataatctcag gaagacaaga aaaatcatgt
      541 ttaaagtgaa agtcattgag cttacgaata acagttgaag ttgagatgga aagctgatgg
      601 gcaatatcag tcatagaaat cttttcaatt aacttttgag caatcttttg gttgatgata
      661 cgagggattt ggtgattctt cttgacgata gaagtttcag cgaccatcat ttttgaacag
      721 tgatagcact tgaatcgacg ctttctaagg agaattctag taggcatacc agtcgtttca
      781 agataaggaa ttttagaagg tttttgaaag tcatatttct tcaattggtt tccgcactca
      841 gggcaagatg gggcgtcgta gtccagtttg gcgatgattt ccttgtgtgt atccttcttg
      901 atgatgtcta aaatctggat attagggtct ttaatgtcta gtaattttgt gataaaatgt
      961 aattgttcca tatgaatctt tctaatgagt tgttttgtcg cttttcatta taggtcatat
     1021 gggacttttt ttctacaata aaataggctc cataatatct atagtggatt tacccactac
     1081 aaatattata gaaccgtttt tttcagctgg ctccttcttt tttatcctca aaattctatc
     1141 ttatactcaa tgaaaatcaa agagcaaact aggaaactag ccgcaggctg tacttgagta
     1201 cggcaaggcg acgttgacgt ggtttgaatt tgattttcga agagtcttag gctttctcac
     1261 gaataaccaa aacgccatct tccatatctg cttccagatg tttagtatct aaatgatcca
     1321 agtggaagtc tgtcacctta tcacgaattt cttgttcaac cacgcgacgg agaggacgaa
     1381 cccccatgac ttcgtcgtaa ccttcttctg tgatataatc tttagccgct tgactgacta
     1441 ccaagtcaat gtctttctta gccaaggttt ggttaacttc agccaacatc aaatctacaa
     1501 tcttagaaag gtcttcctta gtcaattgtg agaactcgat gactgcatta aagcggttga
     1561 ggaattctgg acggaagaag ggtttcaaac ggtccatcaa ttctggttta tccgcatctt
     1621 ctgtcaagtt ggcttcatag ccaaatccag catttgaggt cgcaataatg acagtgttct
     1681 tgaagtttac tgtatttcct tgaccatctg tcaaacgacc atcatctaga acttggagga
     1741 gaagggtaat aacttgagga tcagcctttt caatttcatc caagagaatg atagagtatg
     1801 gattgcgacg aacacgttct gttaaggtat tgctattgtc atcataaccc acatagcctg
     1861 ctgttgtacc aattagctta gaaacagctg tgcggtcact gtattcagac atatccaaac
     1921 ggataatcgc atcctgggtt ccaaacatat cgagtgccaa ttgcttagca agctccgtct
     1981 taccaacccc agtagaccct acaaagagga agctgccgat tgggcgattt ccttcatcaa
     2041 aaccagcacg gttacgacgg atagcgcgag ctacagcttc tacggcctta tcttgaccaa
     2101 tcaccttgtc ttgcaagcga tgagccatat ctttcaaacg ttcgatatct gaagctccca
     2161 tttgcgatac tgggatacct gtcattcgtt ccacagattc agccacatcg ttgacacttg
     2221 cagtcacttt catatcttct gtgtggtttt cgattttctt ttccaattct gcaatgcgtg
     2281 ttttatagtt tagagctgct tcaaaatctt ctgcttcaac tgctttttct tgcttgtctt
     2341 tttccgtttc gatttctcgt tcaacagcat gcacatctgt tactggatgt tgagccgcca
     2401 agtgagcagc cgttacatcg acaaggtcaa tagccttatc tggcaagcta cgttgaggaa
     2461 tgtattgaac agaataatcc accgctgctt tcaagacttc gtctggcaag atgacattgt
     2521 ggtgttgttg atagaggtca cgaattcctt gaagaatttt aaaagtattc tctgccgaag
     2581 gagcattgac cttcacttcg ttgaaacgac gagcaagagc agcattcttc aagatggtgt
     2641 tacggtattc gtcttgagtt gttgccccaa tcactgtcaa ttctccacga gagagagctg
     2701 gcttgagaat atccgcaagt cctttagaac cactgtctcc accagtgcta ccagcaccaa
     2761 gaatttggtg aatttcatca aagaagagga taatattccc tgcttctttc acttcattga
     2821 ctaagttttg gacattttct tcaaagctac cacggtattg agtaccagcc tcaagacctg
     2881 agatatcaat agaaataatt tccttgttct tgatagcagc aggaacatct ccgttcacaa
     2941 tggcttgcgc tagaccttcg acaactgctg tcttaccaac acctgcatct ccgaccaaaa
     3001 caggattgtt cttggtgcgg cgtgagagga tttcagatgt ttcttgaatt tccttgtttc
     3061 gtccgataac aggatccaac ttgccctcac gcgcttctgc tgttaagttt cgacctagtt
     3121 ttgcaaggac accgtcttgt ttcatacctg atgcctgttg tggcatttgc acatcagttt
     3181 ctgcatttcc tggtaattga ccagtcgcac gatagtgagc aaattcctca ggtgtgactt
     3241 cgcgtccatt aattaagtaa cggcgatttt cagaactgta tcctcgcata ccacccatca
     3301 attggttaaa taaatcatcc atgttattaa aattattaaa gttgttattc atattcttta
     3361 cctctttttg tttacttagt tatgattact gatattgact atctttgacc attgttttaa
     3421 aaaatttaga ctagctagat cgctacccta cgtactattt ctggtttttc tttttcaagc
     3481 aggagtagac tatctttact tctgaagatt tctagatgaa acatagaccc acctctttct
     3541 attttacttt aaataagtgt tctagtaagg ctttcattta ccttacgttc ataatatact
     3601 acattggtca gaaaaggtca agagttttga ctttaactga ccaatatttt tttacactct
     3661 tcgaaaacct cttcaaacca catcagcttc tccttatcta caacctcaaa accgtgtttt
     3721 gagctgactt cgtcagttct atcaaccatc tcaaaactgt atattaaaac gaaataagaa
     3781 caggacaaat caatcaggac agtcaaatcg atttctaaca atattttaga agtagatgtg
     3841 tactattcta gtttcaatct actatatttt gagcagccta aagttagctt tctagtttgt
     3901 tctttgattt tcattgtgta tttaaacaca aaaacaccct gaaacatcag ggtgccattc
     3961 ttacatcaaa tataaaattg ctagggtcag gagacttgct agaagtccca ctccccaaaa
     4021 gaagaagtca accttccact cgctccaagg atttccttta ccagacaatc ccccaagctc
     4081 aaaatggtga tgtacaggcg tcatacggaa aatacgttta ccacctgtca gtttgaaata
     4141 actgacttgc atcataacag aagttgtttc aaaaacatac acaattccga taatcaagag
     4201 agtccattct tggtggagag ccatagagat agctgccagc atcccaccta gggccaaact
     4261 tcccacatca cccataaaga ccttggcagg cttatggtta aagatgaaga aaccgagcaa
     4321 accaccaatc atggcaagaa tcactagaag aatatccatc tgaccttgca cataggcaat
     4381 aactccatag gcagacaaac taatcacaac ggaaatacta gctaaaccgt caacaccgtc
     4441 tgtcaagttt actgcgtttg aaaaaccgac tagccagaaa agagcgaaga aaatatagaa
     4501 aaatcccaaa tgaactggat aaccaaagac agacaggata tcgccaccgc gctcatagaa
     4561 aagatagaag ataactccac ctagaagctg aagagctaat ttttgcttag gattaagccc
     4621 ctcattgatt ttacgaaaga ccttgagaaa gtcatctaaa aatccgacca agccatacaa
     4681 gaccaagatg aacaaaatca ttcccacatt attgctgaat tggctactaa atagggcgaa
     4741 aaagaaagca accaaaacag aagtaatcaa gaaaaccaaa cctcccattg taggagtccc
     4801 agcttttgcc tgatgctgtt tgacatcttc atgcatctgc tgtcctgtaa tttgcgcctt
     4861 tctataaaat tggataaagg ccggaattcc tactaaagtt agtaaaaatg tcacaattcc
     4921 agcactgatg gaaataaaca tattagtctc ctaaagttaa tgtaattttt ttaatgtcct
     4981 tgatagctgt gttagcacga acatcttgct tctgcacagt agagcccgaa ccttgaaatt
     5041 caagttctat attgagccac ttagcaaggg tctcagcagt ctcctttgtc caaccataca
     5101 tatctggaac ttcctctgct ttatcagata agataaggac ttgctgattc ggggcaagat
     5161 tcttcccttc ttcagcagaa ctgtttttaa tcttcgttcc tgttcccaca acgatgggtt
     5221 gtacaagatt gcgacgcaat tcttctgcta aatcaccagg tgaaatatcc ttgacactag
     5281 gcataggata aggactttgt tgacttactt gctccaaagc tttagctgtt gtttgaagat
     5341 tgagagagtc tttcatagct gaagcccgct ccaagatagg attggcaaat tctcccaact
     5401 gaatacctga ataatgttca ggttgttgga ccgtcacata caagataaaa tcaggatttt
     5461 cagccggact catcgataca gccgagaaaa tatagtcggt taccccgact agataaccac
     5521 catttttctc gtcagcaatc tgagccgtac cagacttgag ggctacattt tgcccaggaa
     5581 cagttacagt tggcttgcct gtgctgtggt tatacatggt tccataaacc ggatccgtcc
     5641 ctaccaaaac catgttagtc cgagttagac tagctgcatc tttagaaaca ggatttccca
     5701 caatttcttt ttgagatttc cgagcagttt gatcatttgg atcataaatg gcactaataa
     5761 atttaggctc cagcatgaca ccgtcattag caatagctgt aaaggcacga atcatttgcg
     5821 tctgggtcac tgaaatccct tgtccaaatg agctttgcgc aatgttgaca atattatccg
     5881 caggaagctg accagcatac tcatccgtca aaccgaaacg ggtcggaact ccaaatttaa
     5941 aacgattaag ataatcaagc caggtagcat ctcccatctt ttgctcaagg agggtcatcc
     6001 caacgttact tgagtgtgca aaaccttgag aaaaagtcat cattctgcca ccagtcaatc
     6061 cttcattaac gtcccaatct cgaatcgtgg catctgcaat ttttaactca ctactattaa
     6121 agacttctcc tcctggaaag gtattattat caatagcagc agccaacatc atcactttca
     6181 tagtggaacc tggctcatag ttactttggt aaaggatatc acgccaaaca aagtcctctg
     6241 taatgccttc ttttgtatct gcatcaaagg tcggtcgttg cgttgttgcc agaatttccc
     6301 ctgttttagc actgaccaaa gtcgctgtca tgtactttcc ttttaccttc tcttgaaaag
     6361 catccatctg ggtttccata aaggactgga gggggctgga aatggttgta taaacatcct
     6421 taccgtccat cgttcgttgg gaaacttgtt ctgttccggg tacaatatta cccagacgat
     6481 ccttttcata ggtaataatg ccgtctgtcc ctgcaagaat actgttcaag gaactctcca
     6541 ttccagaggt tcccagcaag ctcttgcttc catcttcatt ttcatggagc tgagctaggc
     6601 cgataaaact agaagcaaat tgtccgtttg ggtaactacg attgggactg gttgtaaaat
     6661 caatcccctt gacctctgca gcttccaatt cttttttgat agacatcata ttggcatagg
     6721 taatcccatt tccctttgct ccaaaggaaa cttgcttgag attaggttgc gagagttgct
     6781 ctcttacata ggattcttcc atgtccaaat acttatgaaa gacctctgca accttgttaa
     6841 attgtgtttt ttctacgtaa agaatcttac ccgttgctga cttatagttc tcatcaatga
     6901 ccgcatagac attataggag gttgcatcct cagcaatcgg gactccattt cggtcataaa
     6961 tagtcccacg tttggcagga actgtacggg tggtttgatg aactttctta gcttccttcg
     7021 ctaaatctgt tccaaagcga gtgcctgtcc caataatgac cgcaaaattg actaaaaaaa
     7081 tggcaaaaac aaagacagat aataaactca gactttttcc aactctgcgt ctgttttcag
     7141 ccggcgattt ccgatttttg gtcgcataac ggattactct ttttgtccac ttcatatctt
     7201 actccgctat tctaatattt tcattgttta attgcaaatc gtgtgaattg gcaatttctt
     7261 tcaaacgttc tgcacgtaat agttcattga cctcttgctt ggcatcgtcc aattcggttt
     7321 tcttttcctc tatctgcgca ttgatttttg tcaaatcatt ctgcacttgc aagagcttgg
     7381 tctgcataaa aataatacta atggctacaa taagagtggt tacagcaatg gaaaagtaaa
     7441 aagctttttc cacacgcgaa aaccgtttaa gttgcatctg tagtatttga cctgtttttt
     7501 ccattttttc tgccatcttt ttccctctta cttgtgaatt tttctggcca cgcgcaactt
     7561 ggctgagtgc gagcggttat tggcttctaa ctcttccgca cttggcaaga ttggcttacg
     7621 ggacaccaat tccatcttgg gcttgagatc atctgggatg aaaggcaagc cttttggaac
     7681 ttcaactgtt gaagcttcct tgaacaattg cttggtcaag cggtcttcta aggaatgaaa
     7741 ggtaatcact gaaattctac catccagagc caacatatcc atagcctgct ggatggactc
     7801 atctgccgcc cccagttcat cattgacttc aattcgaata gcctggaaaa tctgcttagc
     7861 aggatgcccc ttcttcttga gttccttggc aggtttgacc aacttgataa tctctgctaa
     7921 ctcagtcgtt gtctcaatcg gcttcacttc acgcgcttgc tcaatcttac gcgcaatctg
     7981 tttagagaat ttgtcctctc catacttgaa gaaaatacga accaagtcat gatagtcata
     8041 attgttcacc acttcatacg ctgtcagact agcatcctga ttcatccgca tgtccagtgg
     8101 cgcatccttt ttataagaaa aaccacgctc acgctggtct aattgaggac tagacactcc
     8161 caagtcataa caaattccat caatttcctg aacaccagct tcgcgcaaac gtgcctgtaa
     8221 atgacggaag ttgtccttga taaaggtcac cattcccttc tcaatgtaag gtgccaagcg
     8281 tttttgcgca ttgtcaatgg cattctgatc ctggtcaaag gcatagagat ggcctttttc
     8341 acttaattta cttaataaat actcgctatg gcctgctcca cccaaagtcg catcaacgta
     8401 gataccgtca ggttttacgt caagcatatc aatcgtttcg tggagtaaga ccgttacatg
     8461 atgaaattct tttgtcatat cttatctatt ttaccacaaa tccgaccagc ttgcacttgt
     8521 cagacaaata ggacaaggag actactattt cttcaaaaaa tatgtcaaaa atacttgaca
     8581 ctttatgttt aaaagactat aatatagtca aatatatacg acataaatca gaaaggagac
     8641 cagatgaatc gtgtgaaaga atttcgcaag gaattgggta tttcccagct cgaactcgcc
     8701 aaggatatcg gtgtctcgag acagactatc aatatgattg aaaacgacaa gtacaatcca
     8761 accttggaac tctgtctcaa tctcgcccgc agcctccaaa ctgacctcaa cagtctcttt
     8821 tgggaggaag atttttaaaa aaggagcaaa ctcatgaaaa aagaaacctt cactgaaaaa
     8881 ctgatcaaac gcacatacgg tatttctggt ccccttgacg aatacaaacg gcgtgaggcc
     8941 gatagtattg ggaaccaagt ctttatcgtc ctcttttatc tgatgatttt cggaaatatt
     9001 attccactcc ttctggccta taaataccct caagaagtgg ctctaatcta tcctcctctg
     9061 attttagtga ttgccctcat cgcttctggc tatgtcacct accaaatgaa aaaaacaggc
     9121 atcacagtca ttgaaccaga tatgctgaat gagaaagaaa gcaagcaact acactaccct
     9181 ggtctgaaag caggtttgtt ctttggtcta tggatgtttt ttataactcc tcttctcagt
     9241 atactcatag atgaaggtca ggactatttt cattctcttc tcactataag aaatggtgta
     9301 tcaagtattc tcggttctat tttcttcgga gcgagcatac agttcctcat ctcccgtcgc
     9361 attgcaaaaa ctaagaaaaa tcaagatgag gattaggagg aaactcatga aaaaagaaaa
     9421 gaaacagtta cgttatcctg gtctgaaagc aggttcgatt tatggaacag tgatattttt
     9481 tataattcca ctcattgata ccctaacaag tgaaaatcca aattttatca gttctcttct
     9541 aaatacaaaa catattttta aaactatact gggagctttc tttttcggag tgatgataca
     9601 tattgtcgac tcacttcgta ttgcaagagc taaaaaagac caggattagg aggtgcctta
     9661 tgaaatcact agctagacta ctgatcattc atgtttttat cagtattttc cttttcttcg
     9721 cccttacttc aggagctatt tctcatacag ttttactact cctactcctc tttcttcctg
     9781 cgctcaataa aggacttgag aaaatacaat caaaacggat acctgtcctc aacgcagccc
     9841 tcttctttct cctcatatcc tttccacaac ttttaaccaa ccctgtccaa tggaaatttt
     9901 caatattcct agtcgtaacc atcatttcaa gtttggccta cttctataac ttttatcaag
     9961 tagttaaaga agtagatcaa aaacagttga tttaggagct tgctcccata atttctcatt
    10021 ttataggcaa ataatcccac ctagcttgtt ctaggtggga ttattttatt tcttaacaga
    10081 gattgcaagt cattttcctt cattttagaa agtcgactct ttccaattca cactacaatc
    10141 caagacttgt tgcctttctt cttgattgcg accttcaatc tggtcaatca aaatctttgt
    10201 agcctgttgt ccttcctcaa aggagggctg aaccagcgtc gaaacacttg gagaagaaaa
    10261 gcaagtccac tccgtattgt caaaaccaat caacccaact tgcggcaagt tataattcaa
    10321 ctctttgata acggtaaaga ctagaggtag ggcccaacag ttagggataa ataccagagt
    10381 tttttcatcg ggatcgattt ctttttgtaa aaattcttta atttgttcca aattcgtatg
    10441 cttatcttca atggttagac tggcgtgacg catattagca tctgttaaag catccacaaa
    10501 accacttgcc cgctcaatcc gagtactcaa acgactcgta tccgctgtaa tcaagagaaa
    10561 atgttcataa cctttttcga tacaggactg ggtcatgtca taaacggcat catagttatt
    10621 ggttttaacc cagctagtcc ggtgttcata gagctgacta tcaaaaaaga ccattttctt
    10681 ctttttctca tcgatgatac gagaatattt tcggaaatta gaggtcggct gaataataaa
    10741 gccgtctact cccaagagaa gcatgctttc aatataccgg tcctcactct cttggctgta
    10801 attactattt cctatcatta cctggtagcc attctggctg gcgatatcct caattccctt
    10861 aacaatttgg tttgagaaac tgttggtaat atcaccaatc aaaacaccga ttaattttgt
    10921 tcgtttggag tttaagctac gcgcaacaat gctcggtttg taatttgttt catgaataac
    10981 tttttcaatc ttttcacgtg tctcttggga cattttttca tatttcccgt ttaggtaaaa
    11041 tgacacggtt gttttcgagg tctgagccat ttccgcaatg tcttttatgg tcagtttctt
    11101 ctccaatcta aaacacctcc tactaatact tattataaca tattcactat tcaaaatgcc
    11161 tatttctagc actgcaagcg aatcattctc tcatttattt tatcatatac tagacatttt
    11221 ccacgcattt ttgttccgtc aacgaggcac aatttttcac ctacacgaat atcctcgctt
    11281 aataacagaa tcagcttgtc tgtttcgtca tttttcactt caaaagccag agcattttcc
    11341 acttcacgat catctgtctg gtagacagaa tgacggatga tttcaaaact ctcatgcgca
    11401 atgatggtat aatccagcat ctgattctca aagaattggc gcttggtgag tttgctactt
    11461 ctttcaagct cattgtattt aggagaaatg atggtatctt ccaaatcaaa atcaacttca
    11521 ctccatagtc tcaactgatt gattttccca tcttgatagg tcacatcctt gtcaaggata
    11581 aactgagtca acgcctcatg ctgaccttga cacctgatgt catctaccaa gagccagaca
    11641 tcctctacca acatgaggat ttttctcttg tgaagataag gcaaatcagg ttctgctgac
    11701 caataagccc cttcaatata atgcactccc tccctttctt tatggtgaca aaacagggag
    11761 tgaggatagt attcatattc ccaggatccc gtgattcttt ccggagcttt cccatctaca
    11821 atgcaggtcg aatgactcca agcactcttt aagagataac gttcatatat ctcccgataa
    11881 gaataacgcc cagcatctat gaaaataggt tggccttgat actgtaagca aaaactattc
    11941 tcgtcactat ggctatgggc acttcctagc ggaccatttt tgaaaaatag ataacgatgt
    12001 tcatccttaa tgcagacatg tccagagtct tcaaagatca tggacttagg ctgccaagct
    12061 ctcctttcaa attcctgcag tcgcttgacc ttttctcgcc ccaggaacaa gaggctaagc
    12121 aaatcgactt taacatccag accgttaaga aggtcttcct tgttcaaaac cacagcagac
    12181 agactcaaaa tttctgtcgt ttctgtagaa tcgctatcac caaaagccaa agttcgtcca
    12241 tctaagcctg tcatcatttg aatataggtc gccatctttt ccagcaactc tcggtaacta
    12301 tcttgcaagt ctggaagcaa gagacacaaa tccagcaagg ctttataaac ctctacatga
    12361 tagagaatcg actgttcaaa ctggcttcca tctcctaaaa tctgtgtctc aatttgctgt
    12421 ttcaactcct ctgaagcaaa atggtaagct tcttctagat ccatcttatc tgaaaagaaa
    12481 taatagatag caagcatcgg aattgtttgt aaaatccccc agttactaag ggtgtacttg
    12541 gcgcgatagt ggcttttcat aaagtcaatc tgcttttcta gactgaccaa aattttctct
    12601 agttctttct cctctagcaa gtcaaatttc aagaggagca agagtagttt caaccaagta
    12661 aaggaacgaa tacccgtatc caaggttcta gtcatcaagg attgaggaga aaattctctc
    12721 acctgctcaa tccaatcaaa tagaaagaac ttgcactttt gaatatagct cttatctcct
    12781 tctaccacat accctatcat aaactgcaag agatattctt gtcgattgag catataagcc
    12841 cattctggat catcttcaaa tacttgatcc cataccatcg gctggatttg atggattttt
    12901 gaacaaggct ccatatccca aggactatca aacataaaac gattgtccat caagcgttca
    12961 agggaacgct tgactttctc atagtctttt gaatagtggg acaagatata atcacgacat
    13021 tggtttccat cgattctttc aaaaaattgt cttctttctt ctttcattat ctattaccag
    13081 aaaaagaact acttaaaaag cagttctttt gtctttccca ttacactttc cttttctaca
    13141 tagatgacca caccttttgc aatctgcaag gagaccaagt catctttgat agaaatgatt
    13201 tttccatgaa ttccagacaa taacaacact tcatcaccag atgttaaaga agctaaatac
    13261 tcttgtcgtt gctccatctg tttgcgaagc aacttttgct gacgaataga atgaaagctt
    13321 gacagtaaaa ggggactcac tgccaagaca atcactattc cataaaacaa tgttgtatcc
    13381 attaagctat aatcttaagc cagcttccga taattccgat gataactgtt aaaataacga
    13441 gtttatatgt tgtccatttc ttttctttga tcaagtagta aactaaaagt gtaaataggg
    13501 ctggtagaag agctggagca accttatcaa gcattccctg aatacttacg atactttgtt
    13561 tagcgtctgc tttaacttcc cctgcagcaa aggtaatcgg caccataatc ttaacagatg
    13621 tcgctgccaa accagcaatt acggttacac cgataatatt ggcaatacga gaaatcgttg
    13681 ccatctgctc gcttagttta tcaatcacag ttgttcctag tttgtatcca tacagaccag
    13741 ttgacaattt aatcgctgtt aaaatcgtat tcatcgcaag gaagaacaag attggaccga
    13801 caaccaagcc ttcttgagca aacgaagctg cgatggttga gaacaatgga gctaaacaga
    13861 attgagaaag agaatcccca atacctgcca atggtcccat caaggccatc ttgatgctac
    13921 gtgtttcttt tgttggtcga ccattttcca acattacaag atgcaagctg gtaataaaag
    13981 gcaggaagtg tgggttggta ttatagaatt cacagttttc ttccaaggct tggtagaaac
    14041 cttcctgatc ctctccatag tgttttttca aagcaggata catcacattg gcatatccca
    14101 acccttgata gttactatag ttaaatccat tttgacaaaa gaatgcccgc aaagacgttt
    14161 taagataatc acgttttgtt aatttgttag atccagtcat cgtgtgcttc ctcctctacc
    14221 acatgatccg ctgtttttgg cttgttataa aattcaatca aagcaaagat agtacctaca
    14281 attgcaatac caattgttgg gatgtttaga taagctgcac aaacatatcc caacaagaca
    14341 aagggaatca actctttctt agccatcact gacaagatca tcgcaaaacc gatagctggg
    14401 agcattttac cagcaactgt caaacctgta agtaataccg gtggaatgta gtctacgagt
    14461 ttcaacaagg tatccattga aagggcaccc aagcaaccca aggtaaatcc aataaaggca
    14521 aacaaccaaa ttgttgcatt tagagtgaac ttaaatttct tcaaattatg gtttttcaag
    14581 tgcttcatcg ctgtttcagg cgcaccagca cgtacagtgt aggcgaaagt ttgtaagaat
    14641 tgaatcgcca cagcaatcgg agtagagagg gcaagagccg cttctggact gactttacca
    14701 gcactagtga tagccatcaa ggtaccaaag ataccaggtc cgattgggtt tggtggaaca
    14761 gtacctccag cacctacacc gaatcccata taagccaatt caccaatagc tcccattgca
    14821 agagcagtag gcagatcacc tagaataatt ccgacaccaa atgacagaac aatacatcta
    14881 ttggtgtaaa ttcctaacag cattccacta aaacagaaag ctgtccataa tccaattaaa
    14941 atcgcttgaa atacattaat cgacataacg atctcctctt ttaaatatag tccataatgt
    15001 tgacttgaac agctccatca tttcctgttg gagttgtttt cgtattaaat gttacttgat
    15061 gagtttggct caattccttg agggctgcct tgtcctcttc acccaggaag atggagcgtg
    15121 tcacttgctc tttaccaggg gcattgtgaa tgttcccaat attgatttct ttgataggga
    15181 caccaccttc taccaaggtt aaagcgtcct ttacatcctt tacaacgata aagatcgttt
    15241 gagcaggatt agccttgtga atgatatcaa tcaccttttg caaagggaag aaacgcatgg
    15301 caactgagtc tggcacaact gttttcatca gagtttgttg catcttgtcc gtgcttactt
    15361 cgtcattggc aacaatgacc gtattacaac ctaggtattt tacccaaagt tgtccttgtc
    15421 catgaatcaa ccgttcatcg atacgggtca taataatatt tggcattgtc atatttctcc
    15481 tcctaccaat ataggttcca gtctttgtag aaacggataa gggcttctag gtaatagtag
    15541 tcaccccaga tattgccttc atccactcct ttacctgaat gccatgagta cacaccgtgg
    15601 aggagacttg tcccaccagg ggtaaattga tcatttgcat aatgttcgat caaggaacga
    15661 agcatggcat gcatagcatg tttataaata tctttgtcag catccacctc tgggagatgt
    15721 tttagcattt catgaatccc acagacggcg atagctgttg ctgaagaatc tcgtgattga
    15781 tcactaccat cattaaaaat caaatcccaa taggacacat gatcttttgg cagacgattc
    15841 aagaaataat tggtcacacc cttaaacaag tcaaagcagg actcgtcttt taagtgacga
    15901 taagtcaaag gaataccata gactccccat gattgaccac gtgcccagca tgaatcatca
    15961 ctataccctt gtctcgttac acctttaaag ggttgacctg tctcaggatc aaaatagaag
    16021 gtgtggaagg acgaagcgtc atcacggatt acattattag ctgaagcata gaaatgactt
    16081 tctgcaatat cgtagtattt ttgatcacct gtttcttgat aagcaaagaa taagagttgg
    16141 atattgagca agcagtcgat aatcaaacgg taatgctctt tcttgcccaa gtctccccaa
    16201 gcttgaataa aaccaccttt ttcttgatag cgttcaatca acttatctgc agctttcaag
    16261 gttgcttctc tagcctctcc atctccattt atcttatatt cagccataca agacggtgtg
    16321 tacaagaagc cgagatcatg gtgatccaat tctactctct tattgacacg atccaggaaa
    16381 gaaagaacat ttttatgagc gatgttttta aatgcatcct gttgactgta ttcataagcc
    16441 aaccacagtt ctcctgtcca gaaaccattg gtccattccg tgttatccat gattggatag
    16501 acattatcaa aggtagctgg cgtcgggaaa tcttccttga aatagtcaag gttgagttct
    16561 aactgccgaa taaccttatc gattgcctgg ccgacttctt ctttcgtcag aagtggtact
    16621 tctaagaagc gctcaggcga ttttattttt tcaatcgtaa ccttttttat cattctttta
    16681 ccctttaaat acccgattcg aaatcttctt cctcttcctc tgcatccgtt gaaaacaatt
    16741 ctttaccatt tacgactccg ccctgggccg ccactactga tttattaaca acctcatcaa
    16801 agctatgagc cattctagca aagactgctt ccattaacat ggctaagttc aaacccgaga
    16861 gaacattcat tgttttggct ggattttctc ccattatggt agaagaaacc ttgaatggcg
    16921 atcctcccaa gagatcactt aggattaaaa cttcttcttc atttgaaatt gcaagtaaga
    16981 ttttttgctt gagttcatct gctgacattc cttccacaaa gtcaatcgcc tccacatttt
    17041 cttgattgcc tgcaatcaat tgtaaagaac tataaatccc tgtagcaaaa tgtccatgcc
    17101 ctacaagtac aattttcatc ttttctcctt tcttgtttag gtttaccggt ttactttata
    17161 ttccccattg taatccttta tttttatctt gtcaatagtt ttttaaaaaa aaaatattag
    17221 cgctttcatt atctttttaa ccattttaat aggcagaaat ttcaaaatct tccgtttttt
    17281 taggaaaaca aaccttttta taaataaaaa tatttattta ttgacaaaac cggtttacta
    17341 gaatataatt tggttataga gaagtcttaa caaatttgaa aggaagtatc aaatgacaaa
    17401 tacatcattc tcaattgagc agttttcttt aaaaggaaaa attgctctca tcaccggcgc
    17461 ttcttatgga attggatttg ctattgccaa atcctacgct gaagccggcg ctactattgt
    17521 ctttaacgat atcaatcaag atctggtcaa taaagggatt gaagcttatc gtgaagttgg
    17581 catcgaagcc catggatatg tctgtgacgt gacagacgag gacggtatcc aagccatggt
    17641 caagcaaatc gaacaagagg ttggtgtcat tgacatcctc gttaataacg ctggtattat
    17701 ccgccgagtt ccaatgtgcg aaatgagcgc cgctgatttc cgtaaggtca tcgatattga
    17761 cttaaacgca ccatttatcg tttcaaaggc agttattcct tctatgataa agaaagggca
    17821 tggaaagatt atcaatattt gttcgatgat gagcgaactg ggacgtgaaa cagttagcgc
    17881 ttatgctgct gctaaagggg gcttgaaaat gttgacccgc aacattgcgt ctgaatacgg
    17941 tggagccaat atccaatgta acggaattgg accgggttat attgccactc ctcaaacagc
    18001 acctcttcgt gagttgcaag aagatggttc tcgccaccca tttgaccagt tcatcattgc
    18061 aaaaacacct gctgcacgtt ggggaaatcc tgaagatttg atgggccctg ctgtctttct
    18121 cgctagtgat gccagcaatt ttgtcaatgg ccacatccta tatgtagatg gcggtatctt
    18181 agcctacatc ggaaaacaac ctgagtaaaa atagaaagaa gatcttatga aaatcgcatt
    18241 aatcaatgaa aatagtcaag ctagcaagaa tcacattatt tacgatagtc taaaagaagc
    18301 gacagataaa aaagactacc aattatttaa ctatggtatg cgtggagaag aaggagaaag
    18361 tcaattaact tatgtgcaga acggactaat ggctgccatc cttttaaata caaaggcagt
    18421 tgactttgtt gttaccggct gtggtacggg tgtaggggct atgcttgctt taaacagctt
    18481 ccctggtgtt gtctgtggtc tagcagtgga cccaactgac gcttaccttt attctcaaat
    18541 caatggtggt aacgccttgt ctatccctta tgccaaagga tttggctggg gggcagaact
    18601 gaccctcaaa ttgatgtttg aacgcttatt tgctgaagaa atgggcggtg gctacccaag
    18661 agaacgtgta atccctgaac aacgtaacgc tcgtatctta aacgaggtga aacaaatcac
    18721 ccacaatgat ttgatgacca tccttaaaac aatcgaccaa gacttcctca aagacaccat
    18781 ctctggcaaa tacttccaag aatacttctt tgaaaactgc caagatgatg aagtcgctgc
    18841 ttatttgaaa gaagtattag ccaagtaaag ctattctaaa ccagaaagga actaatggat
    18901 gacgaaaata ttactgtttg gcgaaccatt aattcgaatc tcaccattag atgccaccag
    18961 tatcggcgat catgttgcca gttcgactta ttttggcgga tcagaaatta acatcgcttg
    19021 taatttgcaa gccctgggta tctcaacgaa agtctttacc gcactccctg ccaacgagat
    19081 tggagatcgt tttctcacat tcttgaaaca gcaccaaatc gataccagtt caatctgtcg
    19141 gcttggcgat cgaatcggcc tctactattt ggagaacggc tttggttgtc gtcaaagtga
    19201 agttttctac gatcgtaagc atacgagtat cagccagatt cggccaaaca tgctagatat
    19261 ggattctctc tttcagggga ttagccattt tcattttagt ggaatcacca tagctatcgg
    19321 tcaagaggtc cgtgcgatcc ttctcctact cttggaagaa gccaagcgcc gaggaattgt
    19381 cgtttcaatg gatctcaatc tgagaacaaa gatgatttca gtcctagaag ccaagtatga
    19441 attttctaag tttgcacgtt ttactgacta ttgcttcggt attgatcctc tcatgattga
    19501 tgaccaaaat ctagagatgt ttccaagaga cagtgctagc ctagaagagg tggaaaatcg
    19561 catgcgactt ttaaaagaag cctatggttt caaggccatt ttccataccc tccgatctag
    19621 tgatgagcaa gacaaaaatg tctatcaagc ctatgctctg gaagaacgat ttgaagagtc
    19681 tgtccaacta aaaactgcag tctatcaacg aattggtagc ggggatgcct ttatatctgg
    19741 tgccctttac caactactcc atcattcctc cctaaaaact accattgact ttgcagttgc
    19801 gagcgcaact ctcaaatgca ctcttccagg agaccatctc tccacttccg caactagtat
    19861 tgaaaattta ctggcaaatg cacaagatat cattcgttag gagaattaca tgaccaaatc
    19921 agatacgatt attgaactaa aaaaacagaa aattgtcgct gtcattcgag gaaatacaaa
    19981 ggaagaagga ctacaagcct cgattgcttg tatcaagggc ggtatcaaag ctattgaaat
    20041 cgcctatacc aatcagtatg caggacaaat catcaaggaa cttgtagact tgtatcagga
    20101 cgatcagagt gtttgtatcg gtgcaggtac tgtgcttgat gccgtaactg ctagagatgc
    20161 cattctagct ggagcaaatt acgttgtttc tccatctttc catgctgaaa ctgcgaaaat
    20221 gtgcaatctc tacagcacac cgtacattcc aggctgtatt accctcacag agatcacgac
    20281 tgcacttgaa gccggtagtg aaatcatcaa actcttccca ggtagtactc tcagtccagc
    20341 atatatctct gcagtcaagg caccgatccc acaagtttcc gtaatggtaa ccggaggagt
    20401 cggcctaaac aacatccctc aatggttcgc tgctggtgca gatgccgttg gaattggtgg
    20461 cgaactcaat aaactcgctt cccaaggcaa ctttgaccgc atcagcgaga ttgcccaaca
    20521 gtatattaca ctcagataaa atcataacta cccgtctaac gggtggttta tctcagagct
    20581 ataagcccaa atcatcagcc agcgcctaaa gacgctggct ttcacgttgt tcaagcctta
    20641 ttgctcttga ctcgtcactt gcctctttaa gagactttgg tattacttac cactatccct
    20701 aaagggatcc tcatattctt ttacactcaa tttatctagt gctatagtag attgaaactg
    20761 gaatagtata cctctacttc taaaacattg ttaaaaatcg atttgactgt cctgatcgat
    20821 tttgtcctgt tcttatttca ttttactata tatcatactt tactagttct caaattttca
    20881 tactcgtgaa gaaatcatcc actcgataat ttctttaatc ttgactatat ttcttaattg
    20941 tggcttcatt aagccctact ggacttacat aataaccttc cgcccagaaa ttccgattcc
    21001 caaacttgta cttgagattg gcgtgtttgt caaacatcat gagtgcactt ttgcctttta
    21061 aataccccat aaaacttgaa acacttagcc tcgacggaat actgactaac atgtgtacat
    21121 ggtctggcat taagtgaccc tcgatcattt caacaccttt ataactacac aagcgatgaa
    21181 atatttcgcc taaactactt ctatattgat tatagatgac ttttcgtcta tacttagggg
    21241 tgaacacaat atgatagaac acatccactt tgtgtatgat aaactatgag tcttttgtgc
    21301 catatttttt ctcctttcgc tttacaattg gattgaatac ctttattgta tcgcgtttgg
    21361 agtttttttg gtataacctt cgacgcgcac ctcacggagc gagacggact tatatagtgg
    21421 agtgaaatag gatacgaaca aattgattag gaaaatcaaa tgaatttata gaaatctttt
    21481 agcagttata acgttctatt ctagtttcaa aacgctatag tcacataata atgaagtaaa
    21541 aaaggataag tatcaactta tcctttttta aaagaaaaat ccgaagatat ttggccttct
    21601 tcggattttt tctattttcc acagtttcat gtaattcatc tagatgatga acaaattagt
    21661 tgttctttcc tctacggaat agataaaatg ccccaagtag caagaaccct agacttgcca
    21721 agattgactg accttctcct gtctgaggga gattcttttg atccgaatgg ttcttttcct
    21781 cttcagattt ttccttttct tttgaattct gtacttgtgg ctgagctgct tgctctagct
    21841 ttttaaagac ttcctgatct ggagctgatt cctgggtttc aggattatag taggcaatct
    21901 tatattcatc cccttctttt cgaatggtat agactccacg tttcaaaact tggaattggt
    21961 tggaaatagt agagacagaa tcatcatatt tcacaatgcc ccaaactcct tgtttagcat
    22021 cataaacaga ctgaagggtt tcgctatttt cgatgaggct actttctaac tcttttatca
    22081 tttgattgaa ggtggcacga tccacgttag gaattagcat atagccataa gaatctccat
    22141 tttgcttatg agcctgacta atcgtaagaa attcattttc aacttccttg tctgactgtc
    22201 cttcattgat atccttccag gctccctttt gcaaagcctt actcatactg attgaactct
    22261 tcttaaagaa aaagtaacca atattctttt tcgaatcgga cgattctaaa aagacacttt
    22321 gggtttcagg ataatccttt tcttgttctg taagggaggc ttctttatca ttgacataga
    22381 ctttatatgg attacttgat tccagttggt gaaatccatg gttgctgtcg cattggcatc
    22441 atctagtttg ctcgttccaa cgaaagcaga cggtagaact ttacctgtat cgctatccgc
    22501 tctcttagca tccgtctctg ttgtaccagg catcttatat ggattaactg ttggccagta
    22561 gccatcgcta tagtgactca aatcgccatt gtaaagatag aacatcccat cactcgtata
    22621 ccaaccatgt ttattttcct tgttcatgtg ttcgtaattc aaggtacgac tggaaaagag
    22681 tgacaagcca aatccaaacc ctttctctgc attgtacatg gctgttttat ccatcttgtt
    22741 aaaggcagat aggtaacttg ttcttggaac acttgcgact cctgcatcac ttaacaagga
    22801 ttgcatcaaa ctgatatcct tataagtctt caaattctta aagacatcat aataactatc
    22861 cgattgaaca atggtcttca caagactctg caaacgttgt ttggtttctc cttcagacat
    22921 atccgctatt cggtgaatcc ctcttagtac ttctactgcg gccacgtgcc cctcgctatt
    22981 tgcacgactg atcgagcgtc cacgactcat atccatcagc tctccattca ccagcaaagg
    23041 agcaaacgat ttatcaatcc agtggtacat ggtttgcatt ttatctttat cgattggatt
    23101 cttggtcttt tgaatgactg gcaacagttg agacaggcca tcaatcaaaa cattcccata
    23161 agcacccgta taggcaacat tggtatggtc gatataggat ccatcttgat aaaaaccttc
    23221 accttggtct accaacttga acacttgctc aatcgagcga atggtagaag aaatttcttg
    23281 atcatcctta cgcagtaaac cagctattac ttttactctt cccatatcaa ctaagtttcc
    23341 acctagagcc ttaaatgggt tatcagtcgt ctttcggaaa tgttcgggat ctggtacaaa
    23401 tttttcaatc acatctgtat attttttaat ttcctcatca gagaagtatt ctttcatcag
    23461 agacaaggta ttgttgatgg cacgaggtgt accgatttca taatcccacc agttcccaac
    23521 aatgctcttt tcactattgt agacatgttt atgcatccat tccatggaat ccctgactgt
    23581 tcgaacgaca gtttcatctt gataataacg agaagaagga ttggtcactt gcttggccat
    23641 ctcctccaat ttccgataag tggcagtcag atttgcagac attttataat ttgaaaattt
    23701 ttcccacaaa taggtgcggt ccgcctgact tgaaatacta gataggctat cagctacctt
    23761 tccttccaat tcctggttta atttggccat ctgttcattt ttagaatcat agtattgatt
    23821 cccagcaatg atgccattcc agtcatccaa acggtctgtg tatgcatcct taacagaggc
    23881 tagaatcttc aaaggaatct ttttcacttc cttgccatct ttactgacaa tgacattggt
    23941 tgtcccttcc ttaagaggtt ctaaaattcc atttttgact gaagcaacgt caggattttc
    24001 taccttataa gtatagtccg caagagaaaa aacatgtttt tttccaattg gtaaatcaat
    24061 cttttcctca agctgtttat ctgtttgaga atcctcagaa agctgggctg ctacctctac
    24121 cagctcaata tccttaaagg aaacagtccc agttcctgtt tcatagaata actccagctt
    24181 gattttatca acatctaaag tcgggctata gtctgcttca atggtctgcc agtcctttgt
    24241 tcctgacgtc gttgcagaat tccacaatcg cttgtcctta ccactttcct caatgatacg
    24301 aactttggca atcccgactt tatgatctgt tttaatcttg aaacgcagtt tatacttttt
    24361 cttagcttca ataggaacca tacggtgaac cgctgccctt aatttctcag ggcttgagat
    24421 agtgatagcc ccatccttag cctcaatgac tcgagttgag gcatctgcag aactattctt
    24481 ctggtctacc caagctgacc acccctgagc tttgcttcct gtccacggac tgcttccgtc
    24541 ctccgtctga ccaaaatcac cattttcaac taaatttttt gtatcccttt gctgatactg
    24601 aacttccttc tggctttgct gaatggtatt cgtagtcgtt tcttccgctc caactgtcat
    24661 ataatggttt aataaaaatc ctgataaaac aagtgaagac aaactcacaa tgagcttctt
    24721 tgtttttgtt tgcatgtata cactccaata aacatattgt aaaatcaata ggaactaaat
    24781 ctcaaattag agatttatag caactaagta aaccggttta attaaattat accattttta
    24841 aagttatttg taaacggttt ctatcatatt gagggcttat tcttcaacaa tatcttccat
    24901 ccgactcgac gaaaaaagta aaaactgtta caatgtagaa aaagaaaaga ggccctcatg
    24961 acttcacttt atgatttttc cgttttgaac caaaacaacc aagcaactcc cttggatagc
    25021 tatcgtggca aagttctctt gattgtcaac actgctactg gatgtggttt aacgccccag
    25081 taccagggac ttcaagaact ctatgaacgc tatcaagatc agggctttga aatattggat
    25141 ttcccttgca atcagtttat gggacaagca cccggcagcg cagaggaaat caacgccttc
    25201 tgtagcctac attttcaaac caccttccca cgttttgcca agattaaggt caacggtaag
    25261 gaagcagacc ctctctatgt ctggttaaaa gaccagaaat ccggcccact aggaaaacga
    25321 gtcgaatgga atttcgctaa gtttctcatc ggtcgagatg ggcaagtctt tgaacgcttt
    25381 tcttcaaaaa cagacccaaa acaaattgaa gaggcgatac aaactctact ataattcaca
    25441 atctcactat gattaggttt cctttaacct gatgaatagt gagatttttt gattggcttt
    25501 gacttaaata gaaaaacacc ccatgatatg aaacatgaag tgttgtaaag tctatgttgt
    25561 aggtgcttat ttcacatttt caatgtgacc agtgataacg aataccatac agaatcttca
    25621 tatacactaa acaaatgact ttctaattat atcaattagt tttggctagt aaatatcatt
    25681 tccaacaaac gccctctcaa ttccttatcc tgatgatgca agatattcat taagtcatga
    25741 gagtttttcg cattgatgaa ttgatttaac aatctatctt ttaattcata tggaagagaa
    25801 gctgtcttta gtagtctaaa aacttcatca tttaaagata ttgttttatt atctttacat
    25861 tcaaatctag ctgtatcatt cttatttggt aattcaatta tagacacatt cgttccttta
    25921 aaatgaattc tatgccttct attgcttgga acgatactag aatctccttg taatgttaac
    25981 tctaccatcc ccatttccca atcgattgat aatcttgttt tatatctttg accattttga
    26041 tcttcaagca tttcaaaaga atgttgtttg cctgggaata cataccaatc tacaacttca
    26101 ggtaaatcaa cacccatatc tatctcagaa ccaaccaagg gaatgatcgc accacttttt
    26161 gcaaacacag gtatagtcga aatgtctcta taaacactca acttcacacc acctgtatat
    26221 tttttctctg aaaagaagtc ataccattca ccttcaggga accatacatc cacttttgca
    26281 gattggaatg ccaagtccat cttttctaca atgggagcca ccattagttc tgttccaaaa
    26341 aagtattggt ttggaacatt atagctctca tcattctctg ggtagaaata atacattggg
    26401 ctgattaatg gggcaccttc ctcgtgtgtc tttacattca tagtgtatag atatggaatc
    26461 atctgatgcc tcaaacgaag gtatttcttc ataatcttag atgttgtttc tgaaaaaaac
    26521 caaggttctt tactattaaa aggacttcta gaactatgta atcgagtgat cggactaaaa
    26581 acaccaaact gtagccatct agtttgcagc tcttcgtcat aatctcccag catgtgccca
    26641 ccgatatcat ggctccacca actataaccg atattagatg ctgtcgctgt aaaataaggt
    26701 tgaaatctta aggaattcca actaataata gtgtcccctg aaaaaccaac agggtagcgg
    26761 tggctaccag gacctgcata tcttgataaa atcaaaccac cttctgcatt tttacaacta
    26821 tcctgataat gataatggtt taaaagccat agtggatcca atatgccttg agtcccttgt
    26881 tgccagtcaa tccaccaaaa atctactccc tgcttttcta gctcataatg aacatcttta
    26941 aagtaggctt ccctaaaaga gggattaaaa aaatcaaaaa tggcaggttc ttctagttct
    27001 acatttaacc ctaatcgttt ggcgacttga ggataagctt cttcataagc ccgtatacca
    27061 tcagcaggat ggacatttaa agagagtttt aactttctat catgaagttg ttgcaataac
    27121 tgttctggat taggtattaa gtttttattc caactatatc ctgtccagcc acttccaaaa
    27181 cgagctggaa tgtcagttat atgccaatcc atatctaaca caccgataga taatggaatt
    27241 ttctctgttt caaatctgtc tattaaatcc aagtattcat ccgacgtata aggccaatat
    27301 ctactccacc aattccctaa agcatatctt ggtaacaagg gtgttgaacc agtcaaatgg
    27361 taaaagtctc tgattgctcc tctataatca tgcccatagg caaagaaata gaggtcaatt
    27421 tgattttctc tctcaatata accagactgt tcatcccaaa taaatccttg agaatcatcc
    27481 aataaggcta taccatttcg actaataatt ccatcttcta atgggattgc tccatctgcc
    27541 ttatccagag tccgagctgt tccttttaac gtttcaatcg attcaccaaa ataccagcga
    27601 ctaccatata cggcaaaatt tccttttaat tctataaata aattttcggc gttaaattct
    27661 cctttattaa agtgcagatg aaaatagtcc gtcataatat ctagtacgtt tgatgtctcg
    27721 atataatcta acgaaacttg gccaaaatct ctattataga taagttgtgt agttctatcc
    27781 tcaaaactgc cagttttaga gtattctaac cttactagct tgtctgttaa tacagagatg
    27841 cgataaaact ctcccttaaa aattttcaat ttgtttccct ccttttatgg tagcataaaa
    27901 acagaacgca ccatttttga tgcgtttttc attattctga atgcaatgtt ctatctgtta
    27961 tatctatgac aaataatagt caattgaaaa aatgtagtgg acaaaatatc ttttaacaaa
    28021 ccaagagttt attaaagagt tatcactttt caacttttct aagcttatgc agttgtgaaa
    28081 caaactactt ttaaactatt aactaagata ggattgataa ataatttcaa actcttacta
    28141 gcaatcatac aatattcaag ctcacgtgct tttttccttc ctgcttattt cttagaactg
    28201 aagaacccgg atcggtatat aaattatccg gatcaacata gtcataagat tcataacagt
    28261 tgcgcttcat taagtcatcc ccagagcaag agcttcatct cgtaattttt caacatcact
    28321 aaccgtaggt cgccatcctt caatcatatt tgtacttaaa gcataccaaa cactcttaaa
    28381 aacggatcgg ttttcaaaag ctattcccat gattgtcatc ttttctttat ctatatctaa
    28441 ggacatatgc tacctccttt agatacatta taccatgttt ctatgtagct tttaaaaatt
    28501 ttattttgtt tgtcatatct aagttttcag catgcttatc ctattttata agcctcaaac
    28561 ccaaatataa aacgcattct ttttgctttt ttactattgt atcgtattct acgataacat
    28621 actttacttt attgtttttt taaaataaca gcagttccct gtttatcaac tattcgaact
    28681 actttctatt ttgcttcata ccctacatag cgaaaaaata tgaaaaagca gagaagaata
    28741 tcttaaaaag acctcttcac tgctaatgtt aacgctcatt atttaaacta tatggattct
    28801 atcatcgagt atactttttt acttattaga taccttgctc ttctttcacc aatttttgat
    28861 catatacacg gatgaatgga agatagacta ggaatgctgc aaatgcacat actagagcaa
    28921 ctaatacagc tcgaagatct gctgtcccta agaaagctcc aatccctact ggagttggcc
    28981 atggaacctg tgcgataatt ggcttaataa agtttagaga attcgctacg taataaatag
    29041 tagcagtaac cattggtgct aaaataaatg gtatagccaa ggctggatta tagataatag
    29101 gtaatccaaa aattaatggt tcattaatat taaataaggc tggaactaca gatgctcgtc
    29161 ctattgcttt aagctgttca gatttagagg caaaagcaat atataaacat agtcctaaag
    29221 ttgcaccaga accacctgca attacaaaca tattagaaaa ttcacctgca acagcgaagt
    29281 gcccgccagc agcattttca gccatgttag caagagcaat tggactaaca aatgcaaaaa
    29341 caatgttcgc accgtggata cctacaatcc aaagtagttg agtcagtaaa taaataatca
    29401 ttaaaccaat ccacgaatta gtcagattgg atacaaaacc aaatggaatt gcaatgactt
    29461 taaaaacatc tgttcccatt gctacaagaa gaccgttgat aaagataaca acaaatgcaa
    29521 caacaaatcc cggaaccaaa gcggtaaatc cacgagaaac tccttctgga acagcttcag
    29581 gcattttaat aacccaatta tgtttaacac acatacgata aataataaca gtcacaattg
    29641 ccataatgat tgcggtaaaa atccctgttg tcccaaaacg tgcgactcca tttcccattg
    29701 cccatccatc tgcaattact gcaccttctt ttagacttgt cacagtcttc atcattccac
    29761 catcaaaaat gatttgcggt actgtcatga caaaagccat caaggcaagc aaggcaccat
    29821 taagaggatt catattgagt tcttcttcct ctgcataaat ttttgtcaat tcatatgcaa
    29881 gtgatagaac gaaataaaga gatagagaac ccatagtcgc atagtttgca accatgtaaa
    29941 gtgatgtgaa tttatcaaat gaagcagaga aaatatctgc cacaattggc caaaatgaga
    30001 aagcttgtgg caaaatactg aataccaaaa acattgatcc tacaatagta aatggtacag
    30061 cagccatacc tgcagccgtg atagcacgca ctactttaaa ctgagcaagt ttgcccattg
    30121 gtcccataac atggttttca agaaaaccaa acaacccgtt ttgttgatcc ataaatagac
    30181 ctccttaata aaacataata atttttactt tctaaagact agtttcaaat acaaattata
    30241 ctagatcagg attataaact aagtgagttc ttttccaatt ggacaaattg ttgataagcc
    30301 ttatctgttc gtttataaat ttttttaatt cttctaatgt ctaacaaact cagaactaaa
    30361 cctaatagaa gaactacaaa aacaaataaa cgtgctactt ggttattttc aaaaatcgga
    30421 aaaagattct taaaccaact tgtccaagtt aaaacaagta atcctattga aataagcatt
    30481 tgtattctaa caaacattag tgttattccc aacttttctt tcctatttcc atagagttta
    30541 aattgttcaa cagttgctaa aatagaaaat actatgagca taatggggaa aataataata
    30601 ggcgagggat taataaactg attcaaaagc caataaatat tcccaaaaaa gaagagtgct
    30661 attgaataac gtagaagaag atatcgatta aaaaaagtat tagttagagc catctctcga
    30721 cgttgttgtt caatcttttg tcgttctttt ttatccatat catttcctcc ttatataaca
    30781 acacatattt agttaacttt cttataaaga gctaacattt cctttgctac ttctaataat
    30841 gtcatagtgg tcattaaatg atcttgagca tgtaccatga taatttcaat tttaatttcc
    30901 actccacttg cgtattcttg caagagtttg gtttgtgcat gatgcgcttc aagaattatc
    30961 tcatttgatt gatttaattt actttctgca tcatcaaaac taccttctct catttttgca
    31021 aatgcttcat gtatttctga ccttgcattt cccgaatgca ggataatttc aaatgctgca
    31081 acctgcagtt cctcttgatt catatgaacc tcctatttta tcttctcaaa tatgttaata
    31141 aaatcttcaa agttattgca agatattagc tgattttgca attcatcatt ctctgtcaga
    31201 gagactatct ttttagtcac agttgccaaa ccttcgttcc catatattga tggagataga
    31261 agaaatacta gctggacatg tgaactttga ttatcccaga gtaacgaatc tttacaaatt
    31321 gcaaccgaaa cctttccctc tgtaccaaag ggctgaatag gatgcggaac tgcaattttt
    31381 tcagaaaaaa caactgaact taattcttcg cgctgtttaa ttccataaag taaagattgt
    31441 tcaaactcat ttgattcacc aacagataaa ctctcaacca tcttttcaag taaatttacc
    31501 ttgtctgatt cagtacatat taaaaagttt tctttactaa aatactgtct aaagccgttg
    31561 ttttcaaatt tgttaatctt tgatgattgt acataactag aaacttgcat ctgatccata
    31621 gcttttctaa tcatttccat ctcatcactc ttaagaaaca cactaacttt aaaaactggg
    31681 atttgaaaat atagatttga taaatcaaca gctgacacta taaaatctat tcctttaagt
    31741 ttttcttgat tcaattcata atagcctatt acatcaacaa cttctactcg cttcccaaac
    31801 tccgtttcca aacgatttct taacatttgg gctgcaccaa atcctgttgc acaaatagca
    31861 agaatattaa acttagtact ctctttgcta cgttccatag cagctaaaaa gtgaagactt
    31921 acatatgcta cttcatcatc tgatattgtc cactccaaga acttgtccat atttgcaaga
    31981 atttctctag tcataaagaa tatatcacta taattctgtt taatttcatc taccaaaggg
    32041 ttatttaagg taatccggct ttctaaacgt acttgtagtg tcattagatg agttatcaat
    32101 ccttcaatta gttggaaatc tgaagaaaag ttatacatat catctaatcc taaattctga
    32161 aatgttttaa ataaagattt ttttaaaact tcttcagaaa tattcttctg atttttttga
    32221 cattgttgac tcttagctaa caaatgcaaa gtaatgtagt ctatttcctg aactggaaat
    32281 tcctgatttg ttacttctct tactttagaa agaattcttt gggcaacctt tctctctatt
    32341 gcatcatcag tcatctgaca gtctatattt tttatttcaa atccggattt taaacgaatc
    32401 acagacaatg ctatgtgaac tactaagttc tgtagtacaa aatcagatag ttttaggttg
    32461 gcctcttggc attcatccaa aacaattcta gcaaattctt ctaatggaac agtttgatca
    32521 aaaaagttaa attttacata gcaatgtatt gttttaaaaa attgattctc taggaaataa
    32581 tttatgataa aacgtcgttt atcacgttcc tcgcctgaga cataaactcc tttattcgcc
    32641 ctactctcaa tggacaaatt atactctgat aacatcactc gtatctttct gaaatcatga
    32701 gataatgttg aacggctaac gtaaagttca tcagctaaat catcaaaaag aactggaact
    32761 tgctcaaata ataatttatt taagataaat actaaacgat catcaccttt tgaaaccgca
    32821 gttttcgtat agtcttcttc cagttcataa gtttgtctaa actcctggta agcgccttga
    32881 ttctcaaaaa atatttgata cccttgacct tgttttgaaa tcaaccggac tccttgaata
    32941 atcattgtct tctcaattaa tttcagtaca ttacggacag ttctatctga acaggataaa
    33001 tattctgcca gttctttgct tgtaacaaaa cgttccttat tttttattaa aaattgaagg
    33061 atatctttct ctttaatgtt taacacattc attccctcct aaaacgtatg ttttcatata
    33121 ttgaagcata ttatacactt aaatcaattt atatcaaact caaaacaatt tatcttaact
    33181 taaatattta ttgacatttc atgtgttcat caaatattct caagaatcaa attagccatt
    33241 ttttcaattc ccattggaat aggaatatag gcttgaggag gtatttgtac aactggtttt
    33301 cctgctttag aaccagcctc ttcaaattgc ttaaagtaca tttttgtttg agggctgaca
    33361 agatacaaat caaaagctgc tgctgcgata gctttccctc cttcagtagc actaatagca
    33421 tcaactacaa tatctttccc ttttcctttt agaaactctg ttgttttctg tgccataagt
    33481 gatgaagaca ttcctgctgc acaaataatt aaagcttttg ccataatatt ttctcctttt
    33541 cttaaatcca atcaaagctg tgctaagttg acttatctgt tatctatttt tattataaaa
    33601 taaagcgttt ccaatgacaa ttccctcatt ttcctaaatg atatggaaaa aaattattta
    33661 tacttcaatt tataaaataa aattattcct gagagtagaa atgaaacact atttgctaaa
    33721 atcaaaggca agtctcctat acgaatacca tgagcaagcc acaatgcaat atcaataact
    33781 tgcataacat acatacctag agcaatagat cctgtgtcct ttgtcttaac tatacgaaaa
    33841 acttgtggta aaaagcaaat gttgttaaaa ttgctgcaat acttccaatc atatgtcatc
    33901 ccaatatgct aaacaaactg agaataatct cagtttgttt atactattct actgattcac
    33961 cgttagatga aataacttcc ttataccagc caaaagattt tttcggggaa cgattataac
    34021 ttcccttccc attgtcatct ttatctacat aaataaaacc ataacgtttc cgcatttcac
    34081 cggtaccagc tgaaaccaaa tcaatacatc cccatggagt ataacccatt aaatcaacac
    34141 catcttcaac tacagccttt ttcatttcac gaatatgggc acctagatat tcaattctat
    34201 aatcatcatg taccatacca tctgctgcaa cttgatctat agctccaaaa ccattttcaa
    34261 caataaagag tggtaagtga tagtggtctg taaaccaatt taacgcataa cgtaaacctt
    34321 ctggatcaat ttgccactcc cattcagaag ccttaacata attatttttc actaaatctt
    34381 ctgtttcaag ataatcaaaa taaggattat tttcacgatg agagtctata gcaaaggaca
    34441 tatagtaact gaaaccaatg taatctacag tcccaccaag taaatcttct ttatcctggt
    34501 cagtaaaatc aactgaaata ccttttcgtt cccaatactt gaaaatatgc tcaggatatt
    34561 tacctaaaac atgcacatca gcaaaataat aacgcttctg catagctttc attgccatta
    34621 agatatcctt aggattgcaa gtagctggat aaattggaca catcgcaatc atacaaccta
    34681 tttgaaaatc tggattaatc tcatgaccaa tttttacagc tcgtgcagaa gcaactagtt
    34741 cgtaatgtgc tgcttgatac ataattgctt ctctattatc accttcctca tatacaatac
    34801 ctgagttagt aaatggtgca aaatcttcct gataattcgc ttgattattg atttcattga
    34861 aagtcatcca atatttaacc ttatctttgt aacgtttaaa tacgacttct gcaaaacgag
    34921 caaagaaatc aatcaatttc ctatttttcc aaccaccata ttcggtcact aagtgataag
    34981 gcatttcaaa atgagataga gtgatgacag gttcaatacc attctttaag cattcatcaa
    35041 aaagattatc ataaaactgt aatccttctt cattcggctc taactcatca ccttttggaa
    35101 agatacgtgt ccatgcaata gaggtacgga agcacttgaa tcccatttca gcaaaaagtg
    35161 ctatgtcttc tttataacga tgataaaaat ctatcgcctc atgatttgga taatatttac
    35221 cctctaaaac tcccgaagta atttcacgag ctactccatg acgaccagca gtcataacat
    35281 cagcaacact aattcctttg ccaccttctt gccatccgcc ttcaagttga tgagcagcaa
    35341 cagcaccacc ccataaaaat ctatctttaa aagtagtcat cttttttcct cctgactttg
    35401 atactcttat tataaacctc aaaccaaaaa atgaaaacgt attctttttc cttattgtta
    35461 aggaaagaag taatttttaa tggaaataga acaatatctt cttgtattct cgtaatgata
    35521 tctttacgat tttcaatact ttcaaactac aaaaactctc acaataattc taattccctg
    35581 tgtctataaa cgacttatcg ctttctggca tcccagaatc atcttctata taacgttcaa
    35641 cttgcatctg caagtgatat ttttttctta aatctaagat tttctgcatt gtctttgatt
    35701 gataatgttt atctaaagtt tcttgattta tccactgatc aataaggaga atagttccct
    35761 ctttttcaat tggtaaaaaa tattcgtatt tcaagttacc tttttgattt ctaatttctt
    35821 caacaaggcc actatcaagc atttctcttg caaactttat tgcactatct ccatcacctt
    35881 tataatatac atgaatagtc aatgtcatct tatatcctcc aaaatcatcc ttcaatttta
    35941 aaaaaacaag tttagatgag gatctaaact tgttttttat gaactaatta tctaacgttt
    36001 tgccattact ttcaatcact tctttatacc aataaaatga ttttttctta tagcgattta
    36061 tagtcaattg aaacaagaac aagacaaaag agcctcataa aaggtatggc aacttggtaa
    36121 tacctttttg aggtgctttt tgatatgagc ccatgttttc tcaataggat tgtactcagg
    36181 tgagtaggga ggaagaggta aaagtttatg cccaaactcc tcgcataaaa gttctaactt
    36241 acccattcta tggaatcttg cattatccat aatatagtag attgaaacta gaatagtaca
    36301 cctctacttc taaaacattg ttagaattcg atttgattat cctcggtttg tcctattctt
    36361 atttcacctt actataaaaa taaggtaaac ttttgagtgc tttgaaacat tgatataatc
    36421 gtattgatta acgttttgag gcaactgacc ttgtcaggtt gcagccacat ttgtaagcga
    36481 ctaaagtcgc aacaactgtg tcaattgcac caatttagta agaaagtata aaaaaagaac
    36541 accccgaaag gtgctctgta taagtatagt aattctttcg aattaacgtt tactaaattg
    36601 tgatgcttta cgagctttct taagacctgg tttcttacgt tcaactttac gtgagtcacg
    36661 tgtaagaagt cctgcgcgtt tcaatgaatc gcggaagtct gggtctactt gaagaagggc
    36721 acgagcgata ccgtgacgga tagctcctga ttgaccagcg tatccaccac ctacaacgtt
    36781 aacgaaaacg tcgtatgaac ctacagttga agtaactgcg aatggttggt tgatgacaag
    36841 acgaaggtca gcgtgtggga tgtactcttc aacatctttt ttgttaacag tgattttacc
    36901 agttcctgga acaaggcgaa cgcgtgcaac agcgttttta cgacgtccag tacctgcata
    36961 ttgtgcttgt gacatacttt attgttcctt tccttagata agttctgaaa tgtcaagaac
    37021 ttctggttgt tgtgcagcgt gagtgtgctc agctccaaca aatactttca acttcatacc
    37081 ttgagcgcgt ccaagtgtat tgtgtggaag cataccttta actgatttct caatcaaacg
    37141 tactgcattt ttagaacgaa gttcacctgc agagatttgt ttcaatccac ctgggtggtt
    37201 tgagtgagtg tagtagattt tatcagttgc ttttttacca gtcaatttaa ctttttcagc
    37261 attgataaca atcacgaagt cacctgtatc agtgtgtggt gtaaatgttg gtttgttttt
    37321 tccgcgaagt acgctagcaa ctactgcaga aagacgtcca agtggtacat cagttgcgtc
    37381 aactacgtac catttacgtt caacttggcc tggtttagcc ataaatgttg ttttgttcat
    37441 gatttctcct atatatagtt cgatttttgt ttacggtgat gggtgttcct tcccatcgaa
    37501 aagtatttgg aaggttccgg ggcctttcaa atggggtaaa caataccgcc tactatcata
    37561 ccaaatttta cccctaaaag tcaatagata tgaaaaatat ttttcggtaa cttctcaaag
    37621 taactgaaag ttatataatc aagttaattt gggaatttac ctattaactt cggtagattt
    37681 ttgggaattt ttttccttct ttttccctgt agttaaaatc cttttcaaaa aatcaccttt
    37741 tcttgatttt taatcctatt tgctgtatga taagggaaaa gaaaggggac agagatatgg
    37801 cttttaccaa tacccacatg cggtctgcta gttttggcat tgttaccagc ttgcccgatg
    37861 acatcattga ctctttttgg tatatcatcg atcatttctt aaaaaatgtc tttgaattgg
    37921 aagaagaact cgagtttcaa ttgcttaata accaaggaaa gattaccttc cacttttcaa
    37981 gtcaacacct ccctacagcc attgattttg actttaacca tcctttcgac cctcgttatc
    38041 ccccaagagt actggtttta gacatggacg gtagagaaac tatcctcctc ccagaagaaa
    38101 atgacctatt ttaatactca atgaaaatca aagagcaaac taggaagcta accgcaagct
    38161 gtacttgagt acggtaaggc gacgctgacg tggtttgaat ttgattttcg aagagtataa
    38221 aaactctagc cttcagttgc aagtgactga aaactagagt ttttctattt tttcaaagca
    38281 tcatacaagt tgcggatcgg ttgttttaat atcggatgga taaaatgagg cgcaatttcc
    38341 tgtaaggact caaggacaaa aaggcgttcc gctatgtaag gatgaggcaa tatgaggtcg
    38401 tctgtataaa ggatctggtc ctccacaaag agcaagtcca aatcaatcaa acgaggtccc
    38461 caatgcactt ctctcacccg tcccagctct gactcaatgg ctaacaaggt ttctaacaag
    38521 tcttgtgctg gtagccaggt ttccacctca accacttgat tggcaaagct atcctgctcc
    38581 actccacccc aaggctccgt cgctaagaca ctggactctt tgagaatatg gatgccacga
    38641 gctcgcagtt tgtcaatggc ttgcttcaag tttgcttgtt tatctcccat attgcttcct
    38701 agggcgataa aggctcgttg cttgcggcga tgaatggtta ccgagcaagt atctagtgac
    38761 aaatgcaccg gtgcccaagg ttttttcagt tccaacttca tttcttggac aagaggataa
    38821 gactcaaagg tacgttccac cagtttatag gctaccgttt caatcaaatc ttcactcgtt
    38881 tcctgaaacc aagtcgtcca ctgctgacac aattctccgt aatggacaga ggctgttaaa
    38941 tccaagtctg tagctgcctt ggtcatatca taggatagga tggctgaaac gacaaatttc
    39001 tgccccaatt ctttctcact aggaaaaaga ccatgatagg caaacatttc caaatcctta
    39061 atctgcagtt gatccataat gattcctttc tagaaaaatc cgcttgaagc ggattctttt
    39121 tatagcccca ttaaacgata agcttggtca cggagatcct tatctgtttc aaatagacca
    39181 cgagctactg tcgtcaaggt tgcagtgcct ggttttctaa caccacgcat actcatacac
    39241 atatgttccg cctcaatgac aacaaaggct cctttagcac ctagatagtc catcaaggca
    39301 tcggccactt cgatattcaa acgttcttga atttgtggtt ttttcgaata aacttcaacc
    39361 gtacgggcta gcttagacaa gcctgccaca cgaccatctg gaatgtaggc aatgtgcgct
    39421 ctaccataaa atggcaagaa gtggtgttca cacatggtat ggaaaaagat atccttttct
    39481 accaccatat tatcgtcaat aatttcaaag gattttgaca aatgttcctc tgctgtttga
    39541 ccaagacctg aaaaaatctc ttgatacata cgggctacac gagcaggtgt ttcctgcaag
    39601 ccctcgcgat tagcgttctc tcctacagcc tcgataatca tttttacagc tgcttcaatc
    39661 ttttgtgtat ccattctcgt tcttcctctc catcagatag gccctcactt ggctcaagaa
    39721 atacaaggaa cctgtgacaa tcctaactgt ttgtttctct tcttttttat ctgtcaaatt
    39781 ctgctctaga aaatcatgcc aatcttggta gctgagattt ctagccttag ctgcctcttt
    39841 cagcacgctt tcatccgtcg cccgactatc cgcaaaatgt gttagagtaa gctcggtatc
    39901 tggcatggct cccagcaagt ccaacatatc ctccaaggct ttggttttga tacaagtgaa
    39961 gaggatttcc ttatgatgat ccgcaaaacg ttcttgcaag gttaccaaca aggccttgat
    40021 agcatgggga ttgtgggctc catccaaaat catcaaggga tctcttgaca cgatttccaa
    40081 acgccctggc caacttgttt cttccaaggc ttgaccaaga aagtcattgc ttgctagctc
    40141 tcgaccatct tcttgacaaa aagtatcaag taaagctatg gccatcccag cattctctat
    40201 ttggtacaaa ccaagcaggc tagtctggaa gcaaccttgt ctgacagcac ttgtatagtc
    40261 aaagacttcc cctgtcacca cactttcttg atgacgaacc tgataatctg tcccgtaggc
    40321 aagtctcggc gcatctttct cttccgcaat gcggtcaatc acagctaagg cttctggagc
    40381 aatacgccct gttaccaagg gcatcccttg tttgataata cctgccttct gctctgctat
    40441 ggactccaag gtgtcaccaa gtagggccac atgatccaag ccaatagttg taattcctgt
    40501 caaaatgggc tgacagacat tggtactatc caaaagtcca cccatgccaa cttccatgat
    40561 ggccacatct acttgctctg aggcaaagta gtcataggcc agggctgtga taatctcaaa
    40621 ctcggttgtg ccctgtaaat tggcgaccgc ttctccctcc agcaaagact gatagtctgc
    40681 catgagagct tctagcctcg cttctgagat cgattcccca ttgatgctaa tctggtctgt
    40741 gtaatgaatg agatagggcg agctaaacac gccaactctc aaccctagct tttctagcat
    40801 ctttttcaaa aaagcaatag tcgagccctt gccgttagtc cctccgatat ggaggacctt
    40861 gagtttgaga tggggattgc cacgcaaagc taacagttcc accattcgtt ccaagccaaa
    40921 atgcggttga tccgtccggt agttagcaat ccactgattg ttttcaattt ctttcatctt
    40981 atttatattg ttttaaatct aaattttccg cttcatcagc cagacgaatg gcagaggcaa
    41041 tttcaactgc catcctgtga ctagctacgt catgcacgcg caccacttct acaccctgtc
    41101 tcgcagcgat actagttaca tgagccgaag ccgtgtcccg atttcggaaa ccaagctctg
    41161 tctcaggatt gacttcaaaa ccattctcct ctaggatatt gatgacaaat cgcttgcgcg
    41221 acactccgag aaagattgga tagcccttct gatgtagttt atccaggtcc cgtaaaagaa
    41281 gcagattttc tttcttggtc agaccaaagc caattcctgg atccaacagg atattttctg
    41341 gtgcaatacc agcttctgcc gctctcgcta gtgctcgttc aaagaaagcc tccatcaatt
    41401 cttcgattgg caatgtttca aagtccgcta actctttttc tgtaaaggtt tgaccaaaac
    41461 caaaatgagg gaagataagc gaactaggat gctgaggccg agccataact gggttaaaca
    41521 tgatgaccac ttgcgctctc gcttcagcta ccacatgagc cattttctca tcacccataa
    41581 gaccagtgat atcattgact agatcggcac cagcagccaa agcagcctct gctacttgac
    41641 tcttccaagt atcaatagag atgaggacat cactttcctt gcgaatcgct ttgatcactg
    41701 gaacaacacg ctggatttcc tcttctatct caacatagct actgcccggc cgagtcgatt
    41761 ctccgccgat atcgagcata ctggctcctt ctgctatcaa tttacgagcc tgctggagtg
    41821 cctgctcaag agcaaaaaat tgaccaccgt ccgaaaagga gtctggggtt acattgataa
    41881 ttccgcaaat agctgttttt gcatgattgg ctttacttga catatcggtc actccctcaa
    41941 ggcttttcat cttattattt ttctatttta ccataaaaag aaaaagatgg acacgattgc
    42001 attcatcttt ccctagtaga aagaggtcgg tttctacata aaagctttta aacagaaatt
    42061 cctaatgtcc gactcataat caccacaaga gccaacaaac agaaagcaat cccattaaca
    42121 atcatgtgaa gcaagatcga catttccaaa cgttgggtct tgtaggccgt ccaagataga
    42181 actgtcgaca tacctccata aatcaataaa gaaggtaaat tacttggttg atgcaataaa
    42241 gcaaacacaa tcgtaccgac tacaaatccc aagttctcct tgcctcggaa aatcttttta
    42301 ggaacaatcc cacgacacaa gatttcctca caaatcggag caagcaaggc tagcaagaag
    42361 aaactggaaa tcaacgaact attttgaacc atatcattaa tctgagactg gttagctgtt
    42421 gtcgtctcat ttgacagttg caacaagata gaaccaagta tatttgaccc gacaataact
    42481 aaataactca aacccaaacg tgccaaatct ttagctctaa aaaaagaaaa attaaaacta
    42541 gctaacttgg ttttacgagc tcccataata aatagagcca gaaccacaat tgaaaggcca
    42601 gcaaccatca gccctgactg tagcagggct acttctttta aagtcaaaat agaggtaacc
    42661 actaggggaa cctgatataa aaggacggca agtaaaaaga ccaaaatcca gcctgcacga
    42721 ttcaacaatt ctttccacat atttttctct ttcatcacct atctcctttg tattaaaaaa
    42781 ggggggaaat ccccctgggt cattctatta taaggccatg ctaatgtagt taaggataaa
    42841 caaggcatcc aaaatccaaa tcatggcatg aacatcttta acttgacctt taacaagctt
    42901 agtcaaagtg taagtcaaga aaccaactgc aatcccttga gtgatagagt agctgaatcc
    42961 cataaagata gatgtgaaga aggcaggaac tgcttcagac atatcatccc aatggatatt
    43021 tttcaagcta ccaagcatca taatcccaac gataatcaag attggagctg tagccgctgt
    43081 tggtacgatc gctagaagtg ggctaaagaa gcttgaaatc gcaaaacaga tagctacaac
    43141 caaggctgtc aaaccagtac gtccacctgc accgatacca gcagcagact caacataagt
    43201 cgttacgttt gaagtacctg caatggcacc gactgtcgtt ccaatcaaat cagagtaaag
    43261 agccttatcc aatttggctg attggtgatt ttcaccattt gtcgctacaa taccaacttt
    43321 ttcacctgta ccgatcaagg taccaattgt gtcaaaaata tctgtcaatg agaaggcaag
    43381 aatggccatc agagtttcag gcaagcgagc tgtatctgaa accaaagctc ctaaaccttc
    43441 tgaaccaaga gctgcaccaa agattgtctt caaatcttca aaagctgcac caacatggtt
    43501 attagcaaaa tcgatactag acaaatcaac caaaccaact gcaatagcaa gaacagttgt
    43561 tgtcaagata gagagaataa ttcccccttt aatccctttg atgacaaaga agatagtaat
    43621 ggcaagtcct gcaagagcca ctaaaacagc tggattatta aagctgacca atcctggaac
    43681 tgctgaagag tttgctgcaa tcgttgcttg agctttgtca gccccttctc ctacaacagt
    43741 atagttgcct ggatcaatcg tgaatttcaa aagtccagca ttcttaatcc ctacataggc
    43801 aaggaagaca ccgataccag ctgaaatagc tgagcgaaga gcattgggaa tcgattcaat
    43861 gatcatttta cgaacctttg tcaaggtaat aatcaatgaa ataatcccac agatgaagac
    43921 catagctagg gcttcttgcc aagaataacc aagcccgaat acaactgtaa aggtaaagaa
    43981 ggcattgagt cccatacctg gcgcttgggc ataaggtaag ttagcataaa aagccatcat
    44041 caaggtaccc gctactgcac caataatcgt cgctaggaag acaccctgag caggcattcc
    44101 tgtttgtgaa agtatttgtg ggtttacaaa gagaatatag ctcattgcaa agaaagttgt
    44161 taaaccagcg agaacctctg tacgaacgtc tgtaccgttc tcttttagtt taaataattt
    44221 gtccatcatc aatctccttt taatttttac gaacaataat agaattatat catttatcat
    44281 tcactttttc aatgtctttg tttgatttgt ttaagaaatt aatccaattt cattttttgt
    44341 ttggaatctg cttttctgcc tgctttctgt tataatagaa gacatcttat ctgaaaacac
    44401 actagaaagg tccatatgac gaaaaaaatt attgcagttg acctggatgg aaccctgctc
    44461 aactcagaca gtcaaatttc tgactttacc aaaaaaacca tcaaaaaagt tgctgaaaaa
    44521 ggccatcagg ttattattac gacaggtcgc ccttaccgta tgtcaaaaga tttttaccgt
    44581 gaactgggct tagacactcc tatgattaac ttcaacggat cccttactca tttaccagac
    44641 caagtttggg attttgaaaa gtgtttgact gtagacaaaa aatatctgct agatatggtt
    44701 caacgttcag aggacattca agccgatttt atcgctggag aatatcgtaa aaaattctac
    44761 attacaaatc ccaatgaaga gattgccaat cccaaactat ttggtgtaga agctttccag
    44821 cctgaagatc aattccagcc tgaattggtg accaaggacc ctaactgtat cctcttgcag
    44881 accagagcca gtgacaaata tgccttggca aaagacatga acgccttcta ccagcatcaa
    44941 ctttctatca atacctgggg aggtccgctc aatatccttg aatgtacccc aaaaggtgtc
    45001 aacaaggcct ttgctttgga ctacttgctc aagataatga atcgtgacaa aaaagatttg
    45061 attgcctttg gagatgaaca caatgatacc gaaatgctcg cttttgctgg gaagggttat
    45121 gccatgaaaa atgccaatcc agagctactt ccttatgcag atgagcaaat ttcccttacc
    45181 aacgaccaag atggggttgc caaaacccta caagacttat tcttataacc tatactgata
    45241 ctcaatgaga atcaaagagc aaactaggaa gctagccgta ggttgctcaa agcactgctt
    45301 tgaggttgta gatgaagctg acgtggtttg aagagatttt cgaagagtat gaccagcttg
    45361 caagctggtc tttgtgctct tttcacagtc tcatcaacca gttaatcgat tgttctactt
    45421 tttgtctcca aaaccttgga aaaggctttc ttttgtgata tacttcacat ataaatacaa
    45481 gagagctcgt cacactcgac tctgttgaca aaaaatcaat ccagtcccgt tgtccctgtt
    45541 ctcggtcaat atcaaggagg atagctatga aagctgttgt tgtaaatcca gaaagcactg
    45601 gtgttgctat tgaagaaaaa gtactccgtc cacttgaaac tggggaagca cttgtagaag
    45661 ttgaatactg tggcgtttgc cacaccgacc tccacgttgc tcatggtgac tttggtcaag
    45721 tcccaggacg tgttcttggg cacgaaggta tcggtatcgt taaagagatt gctccagatg
    45781 tgaaaagcct taaagtcggt gaccgcgtca gcgttgcttg gttctttgaa ggatgtggca
    45841 cttgcgaata ctgtacaact ggtcgcgaaa ccctttgccg tacagtgaaa aatgctggct
    45901 actcagtaga cggtggtatg gctgaacaat gtatcgtaac tgctgactat gctgtcaaag
    45961 ttcctgacgg acttgatcca gcccaagctt cttctatcac atgtgctgga gtaacaacct
    46021 ataaagctat caaagaagca aaagttgaac caggccaatg ggttgttctt tacggtgctg
    46081 gtggacttgg taacctcgct gttcaatacg ctaaaaaagt attcaatgct catgttatcg
    46141 cagtcgatat caacaatgac aaacttgccc ttgcaaaaga agtaggcgct gacattgtga
    46201 ttaacggcct cgaagttgaa gatgtagctg gactcattaa agaaaaaact gatggaggag
    46261 ctcattcagc tgtcgtaact gctgtgtcta aagttgcctt caaccaggct gttgactcca
    46321 ttcgtgctgg tggtcgcgtc gtcgctgttg gtcttccttc tgaaacgatg gaactcagca
    46381 tcgttaaaac agtcctcgat ggaatccaag tcatcggttc tcttgtcgga actcgtaaag
    46441 acttagaaga agccttccaa tttggtgcag aaggtctggt agtcccagtt gttcaaaaac
    46501 gtccagtaga agatgctgtt gccattttcg acgaaatgga aaaaggccaa atccaaggac
    46561 gtatggtact cgacttcacc cactaatcta atagaaacct attttaaaag ttggaagctt
    46621 cttccaactt ttttatatta aattttaaat aagaattcaa gattactcct caaaaactca
    46681 acatatcaac atata
//
LOCUS       DAVKMJ010000014        45788 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000014 DAVKMJ010000000
VERSION     DAVKMJ010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45788
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.014"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            36..317
                     /locus_tag="VW348_000774"
     CDS             36..317
                     /locus_tag="VW348_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEU9745708.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYQDGVDLLGYTTWS
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            449..1393
                     /gene="manA"
                     /locus_tag="VW348_000775"
     CDS             449..1393
                     /gene="manA"
                     /locus_tag="VW348_000775"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEU9745709.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGSHFILPSDVEAWTLEGQGLELIVSHP"
     gene            complement(1433..2768)
                     /locus_tag="VW348_000776"
                     /pseudo
     CDS             complement(1433..2768)
                     /locus_tag="VW348_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            2996..3745
                     /locus_tag="VW348_000777"
     CDS             2996..3745
                     /locus_tag="VW348_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEU9745710.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSGTAQYTSDAIAAYVQTNAEKIG"
     gene            complement(3765..4220)
                     /locus_tag="VW348_000778"
     CDS             complement(3765..4220)
                     /locus_tag="VW348_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU9745711.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWPGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4240..5415)
                     /locus_tag="VW348_000779"
     CDS             complement(4240..5415)
                     /locus_tag="VW348_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEU9745712.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITELEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5474..6319)
                     /locus_tag="VW348_000780"
     CDS             complement(5474..6319)
                     /locus_tag="VW348_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU9745713.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEDGGLLM
                     GYEID"
     gene            6444..7001
                     /locus_tag="VW348_000781"
     CDS             6444..7001
                     /locus_tag="VW348_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEU9745714.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7020..7487
                     /locus_tag="VW348_000782"
     CDS             7020..7487
                     /locus_tag="VW348_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEU9745715.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7576..8205
                     /gene="upp"
                     /locus_tag="VW348_000783"
     CDS             7576..8205
                     /gene="upp"
                     /locus_tag="VW348_000783"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEU9745716.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8379..8969
                     /gene="clpP"
                     /locus_tag="VW348_000784"
     CDS             8379..8969
                     /gene="clpP"
                     /locus_tag="VW348_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEU9745717.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            9048..9296
                     /locus_tag="VW348_000785"
     CDS             9048..9296
                     /locus_tag="VW348_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEU9745718.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9397..10557
                     /locus_tag="VW348_000786"
     CDS             9397..10557
                     /locus_tag="VW348_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9745719.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVIDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGRDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKNNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            10825..11694
                     /locus_tag="VW348_000787"
     CDS             10825..11694
                     /locus_tag="VW348_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU9745720.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGAISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFEMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11698..12654
                     /locus_tag="VW348_000788"
     CDS             11698..12654
                     /locus_tag="VW348_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEU9745721.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12654..13418
                     /locus_tag="VW348_000789"
     CDS             12654..13418
                     /locus_tag="VW348_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9745722.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKDKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13418..14128
                     /locus_tag="VW348_000790"
     CDS             13418..14128
                     /locus_tag="VW348_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9745723.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14487..15143
                     /locus_tag="VW348_000791"
     CDS             14487..15143
                     /locus_tag="VW348_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU9745724.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQELHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15251..16346
                     /gene="prfB"
                     /locus_tag="VW348_000792"
     CDS             join(15251..15322,15324..16346)
                     /gene="prfB"
                     /locus_tag="VW348_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEU9745725.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16364..17056
                     /gene="ftsE"
                     /locus_tag="VW348_000793"
     CDS             16364..17056
                     /gene="ftsE"
                     /locus_tag="VW348_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEU9745726.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17049..17975
                     /locus_tag="VW348_000794"
     CDS             17049..17975
                     /locus_tag="VW348_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9745727.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYYKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            18261..20441
                     /locus_tag="VW348_000795"
     CDS             18261..20441
                     /locus_tag="VW348_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU9745728.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20493..21308
                     /locus_tag="VW348_000796"
     CDS             20493..21308
                     /locus_tag="VW348_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU9745729.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYNRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            21448..22791
                     /locus_tag="VW348_000797"
     CDS             21448..22791
                     /locus_tag="VW348_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9745730.1"
                     /translation="MSFTKFQFKNYIREALEELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLESNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLEIVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDRNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            23168..24358
                     /locus_tag="VW348_000798"
     CDS             23168..24358
                     /locus_tag="VW348_000798"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEU9745731.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVINK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            24911..25846
                     /locus_tag="VW348_000799"
     CDS             24911..25846
                     /locus_tag="VW348_000799"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEU9745732.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            25880..26917
                     /locus_tag="VW348_000800"
     CDS             25880..26917
                     /locus_tag="VW348_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU9745733.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            27090..27695
                     /locus_tag="VW348_000801"
     CDS             27090..27695
                     /locus_tag="VW348_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEU9745734.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            27852..28382
                     /locus_tag="VW348_000802"
     CDS             27852..28382
                     /locus_tag="VW348_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEU9745735.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            28403..29488
                     /gene="rlmN"
                     /locus_tag="VW348_000803"
     CDS             28403..29488
                     /gene="rlmN"
                     /locus_tag="VW348_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEU9745736.1"
                     /translation="MKPSIHSLVHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFVCTINDDKGMAIGARHITISTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            29488..29970
                     /locus_tag="VW348_000804"
     CDS             29488..29970
                     /locus_tag="VW348_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEU9745737.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKVRN
                     "
     gene            29972..31513
                     /locus_tag="VW348_000805"
     CDS             29972..31513
                     /locus_tag="VW348_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9745738.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(31569..32372)
                     /locus_tag="VW348_000806"
     CDS             complement(31569..32372)
                     /locus_tag="VW348_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEU9745739.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(32455..32676)
                     /locus_tag="VW348_000807"
     CDS             complement(32455..32676)
                     /locus_tag="VW348_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745740.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            complement(33155..33352)
                     /locus_tag="VW348_000808"
     CDS             complement(33155..33352)
                     /locus_tag="VW348_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745741.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKRNMDLLADD
                     SLAGDIILLWRIQFGTFTTET"
     gene            33522..33794
                     /gene="rpsP"
                     /locus_tag="VW348_000809"
     CDS             33522..33794
                     /gene="rpsP"
                     /locus_tag="VW348_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEU9745742.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33814..34053
                     /locus_tag="VW348_000810"
     CDS             33814..34053
                     /locus_tag="VW348_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEU9745743.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            34630..35418
                     /locus_tag="VW348_000811"
     CDS             34630..35418
                     /locus_tag="VW348_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU9745744.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELLE"
     gene            35449..35967
                     /gene="rimM"
                     /locus_tag="VW348_000812"
     CDS             35449..35967
                     /gene="rimM"
                     /locus_tag="VW348_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEU9745745.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            35957..36676
                     /gene="trmD"
                     /locus_tag="VW348_000813"
     CDS             35957..36676
                     /gene="trmD"
                     /locus_tag="VW348_000813"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEU9745746.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRVQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            36688..37026
                     /locus_tag="VW348_000814"
     CDS             36688..37026
                     /locus_tag="VW348_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745747.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(37057..37377)
                     /locus_tag="VW348_000815"
     CDS             complement(37057..37377)
                     /locus_tag="VW348_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745748.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFSKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            37475..37690
                     /locus_tag="VW348_000816"
     CDS             37475..37690
                     /locus_tag="VW348_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEU9745749.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            complement(37849..37935)
                     /locus_tag="VW348_000817"
                     /pseudo
     CDS             complement(37849..37935)
                     /locus_tag="VW348_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(37986..38522)
                     /locus_tag="VW348_000818"
     CDS             complement(37986..38522)
                     /locus_tag="VW348_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEU9745750.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            complement(38719..40065)
                     /gene="gor"
                     /locus_tag="VW348_000819"
     CDS             complement(38719..40065)
                     /gene="gor"
                     /locus_tag="VW348_000819"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEU9745751.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGLYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            40351..41550
                     /locus_tag="VW348_000820"
     CDS             40351..41550
                     /locus_tag="VW348_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEU9745752.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVARADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            41534..42235
                     /locus_tag="VW348_000821"
     CDS             41534..42235
                     /locus_tag="VW348_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9745753.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            42237..43496
                     /locus_tag="VW348_000822"
     CDS             42237..43496
                     /locus_tag="VW348_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9745754.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            43620..45617
                     /gene="metG"
                     /locus_tag="VW348_000823"
     CDS             43620..45617
                     /gene="metG"
                     /locus_tag="VW348_000823"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEU9745755.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLDKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
BASE COUNT        14016 a         8497 c         9981 g        13294 t
ORIGIN      
        1 agtttagtat tatcgtagaa aatggactcg gtgctatgga tacaccggat gagaatggtt
       61 atgtagcaga tgactatcgg attacttact tagaggccca catcaaggcc atgcgagatg
      121 ccatttacca agatggggtt gacttgcttg gttatacgac ttggagctgt atcgatccgg
      181 tttcagctgg cacaggggaa atgaataagc gctatggctt tatctatgta gatcgagata
      241 atgtaggaaa tgggactctc aaacgtagca agaagaagtc cttctattgg tacatgtcat
      301 ttatagcaat ggtgtaagca tcgagtagag cacatttgtt tactattttt ataaaatctt
      361 ctccctgctt tataagatgt aaaaaagagt tcaaatggaa ctcttttttt gctataatga
      421 ggggagaaaa atcagacagg agattaagat gtcagaacca ttatttttac aatcagttat
      481 gcaagaaaaa atctggggtg gtaccaagtt acgtgatgag tttggctacg acatcccaag
      541 tgaaaaagtc ggagagtact gggctatctc agctcatcta aatggtgttt ctaaagttgc
      601 caatggtcgt tacgagggaa cagatcttgc tactttgtat gcggaacacc gtgaattatt
      661 tggcaatcgt ccagaacctg tatttccgct tttgaccaag atcctcgatg ccaacgactg
      721 gctcagtgtc caagttcacc cagacgatgc ttatggactc gagcatgaag gcgaacttgg
      781 aaaaacagaa tgttggtaca tcattgcagc agatgaaggt tcagagatta tctacggtca
      841 caatgccaag tcaaaagaag aactccgcca gcaaatcgag gataagaact gggatgcgct
      901 gttgacaaaa gtgccagtta aagcaggaga tttcttctat gtaccaagcg gtaccatgca
      961 cgctatcggg gcgggtatct tgattcttga aacccagcag tctagcgata ccacttaccg
     1021 tgtctatgac tttgaccgta aggatgacaa gggcaattta cgtgaacttc accttgaaaa
     1081 atctatcgat gtcttgaaca ttggtgaacc cgcaaatagc cgtccagtga caatcaaagc
     1141 agatgatcta cgttccactc tccttgtatc caatgatttc ttcgcagttt acaaatggga
     1201 aattactgga aaagttaact ttgaaaagac agctgactac agcttgttga gtgtcttggc
     1261 tggtcaaggt cagctaactg ttgacgggaa aaattatcca attcaaaaag gcagccactt
     1321 tatcctacca agtgatgttg aagcttggac tctggaaggg caaggtttgg aattgattgt
     1381 tagccatcca taaaaagaaa gggcctgagt tcactactca agtccttttt gattacataa
     1441 attgggcaat gaagaccaca atgatgatga ttggaatgac gaaacgaaga aacgaagaag
     1501 gaagagccag acttggaaca gtccttgttt ccatgctctt tcatcgagat ggagttcctc
     1561 cattgcaaga gcctttttaa agatatagcc tgtaaaaagt gaaaggtaga gagctccaaa
     1621 tggcatgagg agattggaaa ccaagaagtc catagcgtca aagaaggtct taccaaaaat
     1681 gtgaacatcc gccatgacac cgtaagatag ggctgaagga atgccaaaga caaaggtcaa
     1741 aattcctaaa ataacactcc atttggcacg tttgctgtta tcctggttgg tgatattgcc
     1801 cacattgatc tccagcatca cgacagaaga agtgacagtc gcaaagaggg agcggacgta
     1861 gaaaatggtt ccaaaaggca tcttgtcaaa gagttgaggc aagacgataa agagcaggct
     1921 gggtccccct tcagactgga tattgaaggg ggatcgagct tggaaaatgg ctagacctgc
     1981 catgatggat atcgagatat tcatggctac gatggagatt cctgactgga ctagattggt
     2041 tttcttgtcc aagtaagaag cataggtcaa catgactgta acccctagtg agagggcaaa
     2101 gaaagattgt cccagagcat agaggagacc agcgctagtc agttttgaaa agtctggttt
     2161 gaggaagtaa agaacccctt ccatggcatt tggcaaactg agagagcgac tgatgataaa
     2221 aacaaagacg ataaagagca ggggcatcat gactttcgaa gctctttcaa tccctttttg
     2281 aaccccacgt gatacaatga agatattcaa taggataaag gccgcttgag ctcctagggc
     2341 aatggctgga tttgaaatga ttgaagtaaa taactgagca taatcacccg ttccaccaag
     2401 ttggaacaat ttcccaaact caatacctag atagactaga atccatcctc cgataacact
     2461 gtaaaaagat aagaggataa agagggcaaa ggcgccaatc caaccgataa agttgtactt
     2521 gttattcttg cccagttttc caaaggtttt gatagcggaa acgccagcac tacggccaag
     2581 ggcaaactca gccagcagga gagggaaacc gattaaaata gtggaaatga gaaagattag
     2641 taaaaagcct ccaccgccat tagcagcagt catgtaggga aacttccaaa cggaaccaag
     2701 cccgatggcc agccagcaga tgctagaata aaaccaagtt tcgaccccca ttgtgatttt
     2761 tctgacatag ttaaactctg atctcctttt tcaaaataag aaaaagctac ttgagttgtc
     2821 aaatagcctt ctgtttgatt gatagacttg actatcctat catgttttct aaggtctgtc
     2881 aagaaaatca ttttcaagtt ttcacacctt tctcaaaaaa gttaaaaaat tttctcaaaa
     2941 acgcttgact ctgacctaag gggaggggtt atactatcat tgtaaggagg aaatcatgta
     3001 ccatataaaa gaagctgcgc agctttcagg tgtctctgtc aagaccctgc atcactatga
     3061 caagatagga ctcttggtcc ccttaaagtc ggaaaacggc tatcgaacct acagtcaaga
     3121 ggatttggaa cgccttcagg tcattcttta ctacaaatat ctaggctttt ctttagagaa
     3181 aatagcagag ctgttaaagg aagaaaggac agatttattg ccccatttga ctaggcagtt
     3241 ggactatcta actcgcgaaa ggcaacatct ggataccttg atttccacct tgcaaaaaac
     3301 tattcaagaa caaaaaggag aaagaaaaat gaccattgag gaaaaattca cgggatttag
     3361 ctatcaagac aatcaaaaat accaccaaga agcggtagag aaatatggtc aagaagtcat
     3421 gggacaagcg ctcgaacgcc aaaaaggtca cgaagacgag gctacggccg cctttaacca
     3481 agtctttcaa actttggcac aaaatcttca agttggttta cctgcaacag caaccgaaaa
     3541 ccaggagcaa gcagccaagc tcttgcaagc cattcgcact tatggatttg actgctctat
     3601 tgaggtattc ggtcatatcg gtaaaggtta cgtctataac ccagagttta aggaaaacat
     3661 tgacaagttt ggttctggaa cagcccagta cacgtcagat gccattgcag cttacgttca
     3721 gacaaatgca gaaaaaatag gctaggaatt tcctagccta ttttttactt caaatcataa
     3781 agccagtcgt caccgttttt gtagtaaaag aattcactga gatcttcttc tagaaacaca
     3841 cgaagcatat cagacatatc atcggttgca agttttagat gagaaagatt ttcaaagtcc
     3901 tcccaccaaa ctttcccttc gtctgaagac tggagttcac cagtaaagtg ttctgtcttg
     3961 taaaaaagga cgacataacg ataatccttg tcgtcatacc agtttttgat accacagagt
     4021 tggggtttgg aaatgatcag accagtttct tctttcactt cacgaatgac agcatcgaca
     4081 aaggattcgc cacgttcaac atgaccacca ggaaaagtaa tgccaggcca gtcgggacta
     4141 actcggtctt ggaccaggac cttatctccg tttttaatca tacacatgtt aacaaattcg
     4201 actgcctctc ttctgttcat tcttcacaac ctttaatctt taatcataat gcagacttcc
     4261 cgccacccag ccggtacaga gggcagaagt gatgttaaag ccacccgtgt gggcattgat
     4321 atccataact tcgcctgcaa agtggaggcc aggtaccagc ttactttcaa gggttttagg
     4381 attgatttcc ttgagactga ctccaccctt ggtaacaaag gactttgcaa gggacatttt
     4441 tccagttaca ggaattttaa gttctttaat ggactgaaca agttgttctc gttccttttc
     4501 agtcagctgt ttgacttttt caggatatcc ttgtacaaaa aattcggcca agcgttctgg
     4561 taacaaggtt tttaaagcgt ttttcaagga tttttcccga ttttcttcta gaaatgtaac
     4621 caagtccttc tcagaaagtt gaggcaaaac atcgagtgag agaacctccc cacctttgac
     4681 aaagctagac atgcgtaggg cagcaggacc tgacaaacca aagtgggtaa agagtaaatc
     4741 atgagtgatg acatgcttac cataacttag ggtcacatcg tccagagaaa tcccttgtaa
     4801 ggctttatgt ggaaaatctg ttaataaagg actttcagca gcctcaagct cggtgatggt
     4861 atgcttaaaa tggcgagcaa tctcgtgacc aaaaccagtc gaaccagtcg aaggataaga
     4921 cttaccacct gttgtgacaa tgagtttctc acaagtgaag gtttgatccg ctgacttaag
     4981 gacaaactgg tcatctactt ttttaacaga aacgatttct atttgagtag caacttgacc
     5041 acctagttcg gtgattttct tttccaaagc ttcgataata gtccgagact tgtcactggc
     5101 tggaaagacg cgtccgtggt cttcgacctt aagtttaaca ccattttctg taaaaaagtt
     5161 gatgatgtca tgattatcga actgggagaa aacactgtaa agaaagcgtc cgtttccagg
     5221 aattccagct agcaggttgt ctaagctacc attgttggtc acattgcaac gtcccccacc
     5281 agtcccagct aatttttttc caagtttccg atttttttcg atgaggaggg ttttctgtcc
     5341 ataaaagcta ctggaaatcg tagccatcat accagcaggt cccccaccga tgacaatagt
     5401 atcaaaatgt ttcatagctc tattgtacca caaaaaaaca agagatgatg gtcacctctt
     5461 gtcaagaatg caattaatca atttcatagc ccatcagcaa accgccatct tctgcataga
     5521 aactgcagag accagaggtt ggtagaattt taatatccgc ttgtgggaag gtttcacgga
     5581 ttcgctctga gagctgttga caacattttt cgttattgcg ttgggccatg acaatacggc
     5641 caccagcata tccagctttt actaactcat cataggcagc ttgaactgat ttctttgatc
     5701 cccttgcttt ttgtagcaat tcgagagtcc cagtttcact agcttttccg accatacgaa
     5761 tgttgagaag gccaacgacc gtaccgataa gcttgctcaa acggccgttc ttcaccaagt
     5821 tatcgacttt ggctaggaca aagagcaact tagttttttc ttgataggcg gtgatagctt
     5881 caaccacttc ttcaaaagac aagccctggt caatcaagtc attcaatttt tctacgagta
     5941 ggtcaacttc accaccagca gataaactat caatcacatg aatcttagtg tcaggatggt
     6001 cttccagata aatattcttt gctagttgag cactattgtg actgccagaa agggtacctg
     6061 tgatggttac taggaaaatg tttttggcac cttcaaatgc tcgcaaatag tcatctgggc
     6121 ttggacaagc cgattttgaa gcttctgcag ttgcatacat ggtttccatc atttggtcaa
     6181 tatcgagact ggcgtcatca acaaagacct gatcagctac ttgaatggtt aaggggacac
     6241 ttacaaaggt tgtgttaata gctggtgttg gcagttgacg ataatcacaa ccagagtcag
     6301 caataatttt ccaagtcata gaaattctcc atctttgtca gttatacatt gacaaaggtt
     6361 ctgtcttttt ttacaattat atcatgaaaa cccttgaaac aaaagcatca tccgtctgtt
     6421 gtgacaagta gaaagaaaat gttatgtctg aacgtagaat ctctgaaaag tctcttgaaa
     6481 atctcagaaa atcaaaccaa gaatccaatt tattaaccag agaagccatt gaaacagccc
     6541 tcttgcaact cttggaaaaa aaggagctga ccaagattag tatttctgaa ttggtcaaac
     6601 gtgcaggtgt ttcgcgtgcg gccttttatc gcaattatga ctccaaagag gaaattttag
     6661 agagcgtctt taaacgaact gtccacaata ttatggaaca gctgcatcat tacgatttaa
     6721 agacagacct ttatttggtt tgggttcacc ttttccggga ggccagaaag gaagctagag
     6781 tgattcaatt ggccttggat taccatctgg aaaaaatctt tgtccaagcc atgcaggaat
     6841 ttctagaaaa ataccatggg aaatcaaaag gtgtcagctc ttatcttcat tccttctgga
     6901 gctcagccat cgtctctgtc cttctaaaat ggatcaagga tggcatgaag gtaccagctg
     6961 aaaagattgc agatttaggt ttaccatttt ttaaaaaata gagaaaaagg agaaaagaga
     7021 tgactgaaaa aagactggcc tgggatgagt attttgcagc ccaagcccta ctaattgcga
     7081 atcgttccac ttgtaaacgt gctaaagtgg gcgcgattct ggtaaaagat aataaggtta
     7141 tttccactgg ttacaatggt tcggtgtcag ggactgagca ttgtattgat cacgaatgtt
     7201 tggtcattga aggccactgt gttcgcaccc ttcacgctga ggtcaatgct atccttcaag
     7261 gtgctgagcg tggtgttccc aaaggcttta cagcctatgt aacccatttt ccttgtctca
     7321 actgtacaaa acaattgctt caggtcggct gcaagcgcgt ggtttatatc aaccagtacc
     7381 gaatggacga ctacgcccaa tacctttatc aagaaaaagg gacagaattg acccatttac
     7441 cacttgagac agtacagaca gctcttaaag aggctgatct aatgtaaaaa ttatcaaaaa
     7501 taaatggctt agaaagattt ttaaaccgtt ttttggtata ataagaagaa taaattgaaa
     7561 gaaggaattc caaaaatggg aaaaattgaa gttattaatc acccactgat tcaacacaaa
     7621 ttgtcaatct tgcgtcgtac agatacttct acaaaagctt ttcgtgagct agtagatgag
     7681 attgcaatgt tgatggggta tgaagtactt cgtgatcttc cactagaaga tgtggaaatc
     7741 gaaacaccaa ttacaaaaac agttcaaaaa caattggcag gtaagaaatt ggccatcgtc
     7801 ccaatcttgc gtgcaggtat cgggatggtt gatggtctct tgagcttggt tccagctgct
     7861 aaagttggcc acatcggtat gtaccgtgat gaagaaacac ttcaaccagt tgaatacttg
     7921 gtgaaattgc ctgaggacat tgaccaacgt caaattttta tagtagaccc aatgttggca
     7981 acaggtggct cagcaatctt ggctgttgat tctcttaaaa aacgtggcgc atcaaatatc
     8041 aaatttgtct gccttgtatc tgctccagag ggtgtaaaag cccttcaaga agctcatcca
     8101 gatgtagaaa tctttacagc agccttggat gaacgtttga acgaacacgg ttatatcgtt
     8161 ccaggtcttg gagatgctgg agaccgcttg ttcggtacaa aataagatcg aaaagaagaa
     8221 tgacttggaa aagtatttcc agtcacgaaa ggaggttggg tttttgtttc tgtctaatga
     8281 aagcagagca aaaatttgac cttttttgac caagatatta taatagtctt atcttcagtc
     8341 agttgaccaa caaaattaaa actcaaaagg agaaatgaat gattcctgta gttattgaac
     8401 aaacaagccg tggagaacgt tcttacgata tttactcacg tcttctcaaa gaccgcatca
     8461 ttatgctgac aggtccggtt gaagacaata tggctaactc tgttattgcc caattgcttt
     8521 tcttggatgc ccaagatagt acaaaagata tttaccttta tgtcaataca ccaggtggtt
     8581 ctgtttcagc tggtttggca atcgtagata ccatgaactt tatcaaggca gatgtccaaa
     8641 ccatcgttat gggaatggct gcatctatgg gaacagtcat cgcatcaagt ggagcaaaag
     8701 gcaaacgttt catgcttcca aatgctgaat acatgattca ccaaccaatg ggcggtacag
     8761 gtggtggtac ccaacaaact gatatggcta tcgctgcaga acacttgctc aaaactcgta
     8821 ataccttgga aaaaatcttg gctgaaaatt caggtcagtc aatggaaaaa gtccatgcag
     8881 atgcagaacg tgataactgg atgagcgccc aggaaacact tgaatatggc tttattgatg
     8941 aaattatggc caacaattca ttgaactaat gatgatagaa ggcaaactcg actgggtttg
     9001 ctttttttgg tataataggg agagatttct tagaaagagg atttatcatg tttgaaaaag
     9061 tcaatcgctc tggcttgatt atctatcttt actataatcg tgatgccaaa aaattgcagg
     9121 attatggaga tattacctat cattccaaga aacatcgtta cttacaactc tatgttccaa
     9181 ctcaagaagt ggagcaattg gtcggacgct tgagcaagga aaaatttatt aaaaaagtta
     9241 gggtttgtca tatccaagag ttggaaacac cctttgtggg caatctttat cgataggaaa
     9301 acgttatcat agaaaaagtt caaggaaaac attgacaatt ttctgataat tcggtatatt
     9361 cttaacagac tatttaagaa ataaggagac aaaaagatga agaaaaaatt tgccctatcg
     9421 tttgtggcgc ttgcaagtgt agcacttctt gcagcctgtg gagaagtgaa gtctggagca
     9481 gtcaacactg ctggtaactc agtagaggaa aagacaatta aaatcgggtt taactttgaa
     9541 gaatcaggtt ctttagctgc atacggaaca gctgaacaaa aaggtgccca attggctgtt
     9601 gatgaaatca atgccgcagg tggtatcgat ggaaaacaaa tcgaagtaat cgataaagat
     9661 aataagtctg aaacagctga ggctgcttca gttacaacta accttgtaac ccaatctaaa
     9721 gtatcagcag tcgtaggacc tgcgacatct ggtgcgactg cagctgcggt agcgaacgct
     9781 acaaaagcag gtgttccatt gatctcacca agtgcgactc aagatggatt gactaaaggt
     9841 caagattacc tctttattgg aactttccaa gatagcttcc aaggaaaaat tatctcaaac
     9901 tatgtttctg aaaaattaaa tgctaagaaa gttgttcttt acactgacaa tgccagtgac
     9961 tatgctaaag ggattgccaa atctttccgc gagtcataca agggtgaaat cgttgcagat
    10021 gaaactttcg tagcaggtga cacagacttc caagcagccc ttacaaaaat gaaagggaga
    10081 gactttgatg ctatcgttgt tcctggttac tataatgagg ctggtaagat tgtaaaccaa
    10141 gcgcgtggca tgggaattga caaaccaatc gttggtggtg atggattcaa cggtgaggag
    10201 tttgtacaac aagcaactgc tgaaaaagca tcaaacatct actttatctc aggcttctca
    10261 actactgtag aagtttcagc taaagctaaa gccttccttg acgcttaccg tgctaagtac
    10321 aatgaagagc cttcaacatt tgcagccttg gcttatgatt cagttcacct tgtagcaaac
    10381 gcagcaaaag gtgctaaaaa ttcaggtgaa atcaagaata accttgctaa aacaaaagat
    10441 tttgaaggtg taactggtca aacaagcttc gatgcagacc acaacacagt caaaactgct
    10501 tacatgatga ccatgaacaa tggtaaagtt gaagcagcag aagttgtaaa accataatag
    10561 aaaaatgttg aaatagggaa tgagcctttg actcactccc tgtttcgata tttaatactc
    10621 ttcgaaaatc tcttcaaact gcgtcaacgt cgccttggat tatatatgtg actgacttcg
    10681 tcagtcttat ctacaacctc aaagcagtgc tttgagcaac ctgcggctag tttcctagtt
    10741 tgctctttga ttttcattga gtataagaac ctatcaaaaa gtgagggaaa accctcggaa
    10801 ttataaatag aaagagtgaa tcttatgctc caacaactcg taaatggttt gattctaggt
    10861 agtgtttacg cgctgttagc cctaggatat accatggttt acggaattat caagctcatc
    10921 aacttcgccc atggtgatat ttatatgatg ggagccttta tcggttattt cttgatcaat
    10981 tctttccaaa tgaatttctt tgtagcgctt attgtagcta tgctagcgac agctattctt
    11041 ggtgtcgtga ttgagtttct tgcttaccga cctttgcgcc actctactcg tattgctgtt
    11101 ttgattacgg ctattggggt ttctttccta ttggagtatg gaatggtcta tctggttggt
    11161 gccaataccc gtgccttccc tcaagcgatt caaacagttc gatatgattt gggagcaatt
    11221 agcttaacaa atgtgcagtt aatgattttg gccatttcct tgattttgat gattttgtta
    11281 caagtcattg tccaaaagac taagatgggg aaagccatgc gtgcagtatc agtagatagc
    11341 gacgcggcac aattgatggg gatcaatgta aaccgtacga ttagctttac cttcgctttg
    11401 ggttctgctc ttgcgggtgc ggctggtgtt ctgattgctc tttattataa ctctcttgag
    11461 cctttgatgg gggttactcc aggtcttaaa tctttcgttg ccgcagtact tggtggtatc
    11521 ggaattattc ccggtgcggc tcttggtggc tttgtgattg gtctattgga aacctttgcg
    11581 acagcctttg agatgtcaga tttccgtgat gccattgttt atggaatctt gttgttgatc
    11641 ttgattgtcc gcccagctgg tatccttggt aagaatgtga aagagaaggt gtaaacgatg
    11701 aaggaaaatt taaaagttaa tattctatgg ttactccttt tgttagctgg ctatagcttg
    11761 attagtgtac tggtttcagt cggagtactt aatctattct atgtacagat tttacaacaa
    11821 attggaatta atattatttt ggctgttggt ctcaacttaa tcgttggttt ttcaggacaa
    11881 ttttcacttg gtcatgctgg tttcatggcg attggtgcct atgcagcagc tattattggt
    11941 tctaaatcac caacctacgg tgccttcttt ggagctatgc ttgtaggggc tttgctttca
    12001 ggagcagttg ccttacttgt cggcattcca accttgcgct tgaaggggga ctatcttgcg
    12061 gtagcaactc tgggtgtttc tgaaattatc cgtatcttta tcatcaatgg tggaagtctt
    12121 acaaatggtg cggcaggtat cttagggatt cctaacttta caacttggca aatggtttac
    12181 ttctttgtcg tgattacaac cattgcaacc ttgaacttct tgcgtagccc aattggccgt
    12241 tcaaccctct ctgttcgtga agatgaaatc gctgctgagt cagttggggt taatacgact
    12301 aaaattaaaa tcatcgcttt tgtctttggt gccattactg caagtattgc tgggtcactt
    12361 caggcaggat ttatcgggtc tgttgtaccg aaagattaca ccttcatcaa ctcaatcaac
    12421 gttttgatta ttgttgtatt tggtggactc ggttccatta caggtgcgat tgtttcggct
    12481 attgttctgg gaattttgaa tatgcttctc caagatgttg ctagtgtgcg tatgattatt
    12541 tacgctttgg ccttggtatt ggtaatgatt ttcagaccag gtggactcct tggaacgtgg
    12601 gaactgagcc tatcacgttt ctttaaaaaa tctaagaagg aggaacaaaa ctaatggcat
    12661 tacttgaagt aaaacagtta accaaacatt ttggtggtct aacagctgtt ggagatgtga
    12721 ctcttgaatt gaacgaaggg gaactggttg gattaatcgg tccaaacgga gctgggaaaa
    12781 ccaccctttt caaccttttg accggtgttt atgaaccaag cgagggaaca gtaaccctag
    12841 atggtcacct tttgaatggg aaatcacctt ataagattgc ctctttggga cttggacgta
    12901 ctttccaaaa tatccgtctc tttaaagatt taacagtttt agataatgtt ttgattgctt
    12961 ttggaaacca tcacaaacag catgttttta ctagtttctt acgcttacca gctttttaca
    13021 agagtgaaaa agaattaaag gataaagctt tggaattgtt gaaaatcttt gatttagatg
    13081 gtgatgcaga gactcttgct aaaaatcttt cctacggaca acaacgtcgt ttggaaattg
    13141 ttcgtgccct tgctacggaa cctaaaattc tcttcttaga tgaaccagca gcaggtatga
    13201 acccacagga aacagccgaa ttgactgagt taattcgtcg tatcaaagat gaatttaaga
    13261 ttacaatcat gttgattgaa cacgatatga atctggtcat ggaagtaaca gaacgtatct
    13321 acgtacttga atatggccgt ttaattgctc aaggaactcc agacgaaatt aagaccaata
    13381 aacgcgttat cgaagcttat ctaggaggtg aagcctaatg tctatgttaa aagttgaaaa
    13441 tctttctgtg cattacggta tgatccaagc agtccgtgat gtaagctttg aagttaatga
    13501 aggagaagtt gtttccctta tcggtgccaa cggtgcaggt aagacaacta ttcttcgcac
    13561 cttgtcaggt ttggttcgac caagttcagg aaagattgaa tttttaggtc aagaaatcca
    13621 aaaaatgcca gctcagaaaa tcgtggcagg tggtctttca caagttccag aaggacgcca
    13681 cgtctttcct ggcttgactg ttatggaaaa tcttgaaatg ggagctttct taaagaaaaa
    13741 tcgtgaagaa aatcaagcta acttgaagaa ggttttctca cgctttcctc gtcttgaaga
    13801 acggaagaac caagatgcag ctactctttc aggaggggaa caacaaatgc ttgccatggg
    13861 acgcgctctt atgtcaacac caaaacttct tcttttagat gaaccatcaa tgggacttgc
    13921 cccaatcttc atccaagaga tttttgatat cattcaagat attcagaagc aaggaacaac
    13981 cgtcctcttg attgaacaaa atgccaataa agcacttgca atctctgacc gaggatatgt
    14041 attggaaaca ggaaaaatcg tcctatcagg aacaggaaaa gaactcgctt catcagaaga
    14101 agtcagaaaa gcatatctag gtggctaaaa caatccagtg gattgtttta gtcggcagat
    14161 gaagattacg aagtaatcat caatatagtc cgggggccct ttttagtcgg tggatgaaga
    14221 ttgcgaagca atcatcaaat ccagaggatt gttttagccg gtagattgag attgcaaaca
    14281 aatctgcatc tacattgaaa gctgaatttc taataattga aaaaatcgaa tgaaacgtat
    14341 cttaccttca ttcagggagc tcgattttag agctcttttt gctagcttat tcatactttt
    14401 ttgaatttcg aaaaagaaat gtaagcgttt gatagattta caaaaagatt gtataatggg
    14461 gataagaata gaaaaggaga agtctcatgg cagttaaaga ttttatgacc cgcaaggtag
    14521 tttatattag tccagataca acagtatctc atgcagcaga tttgatgaga gagcaagaat
    14581 tgcaccgctt gcctgttatc gaaaatgatc aattggttgg tttggtgact gagggaacca
    14641 ttgcacaagc aagtccatct aaagcaacaa gtctttctat ctatgagatg aattatcttc
    14701 tgaataagac aaaagtaaaa gatgtcatga ttcgcgatgt tgtcactgtc tcaggctatg
    14761 ctagtctaga agatgcaact tatctgatgt tgaaaaataa gattggtatt ctccctgtcg
    14821 tagataacca tcaagtatac ggagttatta ctgaccgtga cgttttccaa gcctttcttg
    14881 aaattgcagg ttatggcgaa gaagggattc gtgtacgctt tgttacagaa gatgaagttg
    14941 gtgttcttgg aaaaattgtt tctttgattg tagaagaaaa tttgaatatc tcccatacag
    15001 tcaatattcc gcgtaaggat ggtaaggtca ttatcgaagt gcaaatcgat ggatcaattg
    15061 atttaccagc cttgaaagaa aaatttgaag caaatggtat tcaagtggaa gaaatcgctc
    15121 gcacttcagc aaaagtcttg taagaaggga agcccaaagg cttctttttt catgaaaagg
    15181 ggattagaga aaaagatgga aagaaatgat aaaatatgct ataatgaaat aatgtaaaaa
    15241 aggagtattt atggacattt cagtaattcg tcagaaaatt gacgcaaatc gtgaaaaatt
    15301 agcttctttc agggggtctc tttgacctcg aagggctaga ggaagagatt gccatcttgg
    15361 aaaacaagat gacagaacct gatttttgga acgataatat tgcggcccaa aaaacgtcgc
    15421 aagaattaaa tgaattaaaa aacacttaca ataccttcca taagatggaa gagttgcagg
    15481 atgaagtcga aattttattg gattttttgg ctgaagacga gtcagtgcat gatgaactgg
    15541 tagcgcagtt agccgaactt gataagataa tgaccagcta cgagatgact ctactcttgt
    15601 cagaacctta tgaccacaac aatgccatct tggaaatcca tccaggttct ggtggtactg
    15661 aggcgcagga ctggggtgat atgttgcttc gtatgtatac tcgttatggt aatgctaaag
    15721 gctttaaagt ggaagtgttg gattaccaag caggtgatga ggctggtatt aagtcggtaa
    15781 ctttatcatt tgaagggcct aatgcctatg gtctcctcaa gtcagaaatg ggtgttcacc
    15841 gcttagtgcg aatctcacca tttgactctg ccaaacgtcg ccatacctct ttcacatctg
    15901 tagaagtgat gccagaattg gatgatacta ttgaagtgga aatccgtgaa gatgatatca
    15961 agatggatac cttccgttca ggtggtgccg gtggacaaaa cgtcaataag gtttcaacag
    16021 gtgtacgttt aacccacatt ccaactggaa ttgttgtcca atcaacagtg gatcgtaccc
    16081 agtatggaaa tagagatcgt gccatgaaga tgttgcaggc taagctctat caaatggagc
    16141 aagataagaa ggctgcggag gtagattctc tcaaaggtga gaaaaaggag atcacttggg
    16201 gaagccaaat ccgttcttat gtcttcacgc cttatactat ggtaaaagat caccgaacta
    16261 gctttgaggt tgctcaggta gataaggtta tggatgggga cctagatggt tttatcgatg
    16321 cttatctcaa gtggcgaatt agctaagata gaaaggaact cacatgtcaa ttattgaaat
    16381 gagagatgtc gttaaaaaat acgacaacgg aacaactgct ctacgcggtg tttcggttag
    16441 cgttcaaccg ggggaatttg cttacatcgt aggaccttca ggagcaggga agtcaacttt
    16501 tattcgttct ctgtatcgtg aagtaaaaat cgataaagga agcctatcag ttgctggttt
    16561 taatctggtt aagatcaaaa agaaagatgt cccgcttcta cgtcgtagtg ttggggttgt
    16621 cttccaggat tataaactgt taccaaagaa aactgtctat gaaaatattg cttacgctat
    16681 ggaagtaatc ggggaaaatc gccgtaatat caaaagacga gtgatggaag ttttggactt
    16741 ggttggattg aagcataagg ttcgttcttt tccaaatgaa ctctcaggtg gggagcaaca
    16801 gcgaattgcg attgcgcgtg caattgtaaa taatcccaaa gtattgatag ctgatgagcc
    16861 aacaggaaat ctggatccgg ataattcatg ggaaattatg aatctcttgg aacggattaa
    16921 cctacaagga acaactattt tgatggcgac tcataatagc cagattgtaa ataccttgcg
    16981 ccaccgtgtc attgccattg aaaatggccg tgtcgttcgt gacgaatcaa aaggagagta
    17041 tggatacgat gattagtaga ttttttcgcc atttatttga agccttaaaa agtttgaaac
    17101 gaaatggttg gatgacagta gctgctgtca gttcagtcat gattactttg accttggtgg
    17161 caatatttgc atctgttatt ttcaatacag cgaaactagc tacagatatt gaaaataatg
    17221 tccgtgtagt agtttatatc cgaaaggatg tggaagataa tagtcagaca attgaaaaag
    17281 aaggtcaaac tgttacaaat aatgactact acaaggtata tgattctttg aagaacatgt
    17341 ctacggttaa aagtgttacc ttttcaagta aagaagaaca atatgaaaaa ttaaccgaga
    17401 taatgggaga taactggaaa atctttgaag gagatgccaa tcctctctat gatgcctata
    17461 ttgtagaggc aaacactcca aatgatgtaa aaactatagc cgaagatgct aaaaaaattg
    17521 aaggtgtctc tgaggttcaa gatggcggtg ccaatacaga aagactcttc aagttagctt
    17581 catttatccg tgtttgggga ctagggattg ctgctttgtt aatttttatc gcagtttttt
    17641 tgatttcaaa taccattcgt attaccatta tttcccgcag tcgcgaaatt caaatcatgc
    17701 gcttggtcgg agctaaaaac agttatatcc gtggaccgtt cttgttagaa ggagccttta
    17761 tcggtttatt gggagctatc gcaccatctg ttttggtctt tattgtttat caaattgttt
    17821 atcaatctgt caacaaatcg ttggtagggc aaaatctatc catgattagt ccagatttat
    17881 ttagtccgtt gatgattgcc ctactatttg tgattggggt tttcattggt tcattgggat
    17941 caggaatatc catgcgccga ttcttgaaga tttaggtaaa atagctgctt ttatgaggag
    18001 attgtaaaat ctcctttttt gctacaagag tttttgaaaa gagatgcgca gaagaaaaga
    18061 gcttccaaag aagtccccca gagaagactt cttgatggct aatttgaact tgaaatttga
    18121 ctcactagaa attttttaga aaaaagtgta atttttttat aaaagccttt acaaaaaaaa
    18181 ttaaagtggt ataattaaat tatagaaggt gcaaacgttt tcgtaaaacg tttgcctaaa
    18241 taaaaataaa ggagatttga atgatgaaag atacattcaa aaatgtcttg tctttcgaat
    18301 tttggcaaaa attcggtaag gctttgatgg tagttatcgc ggttatgccg gctgctggtt
    18361 tgatgatttc aatcggtaag tctatcgtga tgattaaccc aacctttaca ccacttgtca
    18421 tcacaggtgg aattcttgag caaatcggtt ggggggttat cggtaacctt cacattttgt
    18481 ttgccctagc cattggagga agctgggcta aagaacgtgc tggtggtgct ttcgccgctg
    18541 gtcttgcctt cattttgatt aaccgtatca ctggtacaat ttttggtgta tcaggcgata
    18601 tgttgaaaaa tccagatgct atggtaacta ctttctttgg tggttcaatc aaagttgctg
    18661 attactttat cagtgttctt gaagctccag ccttgaacat gggggtattc gtagggatta
    18721 tctcaggttt tgtaggggca actgcttaca acaaatacta caacttccgt aaacttcctg
    18781 atgcactttc attcttcaac gggaaacgtt tcgtaccatt tgtagttatt cttcgttcag
    18841 caatcgctgc aattctactt gctgctttct ggccagtagt tcaaacaggt atcaataact
    18901 tcggtatctg gattgccaac tcacaagaaa ctgctccaat tcttgcacca ttcttgtatg
    18961 gtactttgga acgtttgctc ttgccatttg gtcttcacca catgttgact atcccaatga
    19021 actacacagc tcttggtggt acttatgaca ttttaactgg tgcagctaaa ggtactcaag
    19081 tattcggtca agacccacta tggcttgcat gggtaacaga ccttgtaaac cttaaaggta
    19141 ctgatgctag tcaatatcaa cacttgttag atacagtaca tccagctcgt ttcaaagttg
    19201 gacaaatgat cggttcattc ggtatcttga tgggtgtgat tgttgctatc taccgtaatg
    19261 ttgatgctga caagaaacat aaatacaaag gtatgatgat tgcaacagct cttgcaacat
    19321 tcttgacagg ggttactgaa ccaatcgaat acatgttcat gttcatcgca acacctatgt
    19381 atcttgttta ctcacttgtt caaggtgctg ccttcgctat ggctgacgtc gtaaacctac
    19441 gtatgcactc attcggttca atcgagttct tgactcgtac acctattgca atcagtgctg
    19501 gtattggtat ggatatcgtt aacttcgttt gggtaactgt tctctttgct gtaatcatgt
    19561 actttatcgc aaacttcatg attcaaaaat tcaactacgc aactccaggg cgcaacggaa
    19621 actacgaaac tgctgaaggt tcagaagaaa ccagcagcga agtgaaagtt gcagcaggct
    19681 ctcaagctgt aaacattatc aaccttcttg gtggacgtgt aaacatcgtt gatgttgatg
    19741 catgtatgac tcgtcttcgt gtaactgtta aagatgcaga taaagtagga aatgcagagc
    19801 aatggaaagc agaaggagct atgggtcttg tgatgaaagg acaaggggtt caagctatct
    19861 acggtccaaa agctgacatt ttgaaatctg atatccaaga tatccttgat tcaggtgaaa
    19921 tcattcctga aactcttcca agccaaatga ctgaagcaca acaaaacact gttcacttca
    19981 aagatcttac tgaggaagtt tactcagtag cagacggtca agttgttggt ttggaacaag
    20041 taaaggatcc agtatttgct caaaaaatga tgggtgatgg atttgcagta gaacctgcaa
    20101 atggaaacat tgtatctcca gtttcaggta ctgtgtcaag catcttccca acaaaacatg
    20161 cttttggtat tgtgacggaa gcaggtcttg aagtattggt tcacattggt ttggacacag
    20221 taagtcttga aggtaaacca tttacagttc atgttgctga aggacaaaaa gttgcagcag
    20281 gagatctcct tgtcacagct gacttggatg ctatccgtgc agcaggacgt gaaacttcaa
    20341 cagtagttgt cttcacaaat ggtgatgcaa ttaaatcagt taaattagaa aaaacaggtt
    20401 ctcttgcagc taaaacagca gttgctaaag tagaattgta atatacttga ggttggaagc
    20461 tgtattccaa cctcttattt tgggagaaaa gaatgaaatt tttaacactc aatactcaca
    20521 gttggatgga gaaagaagca gaggaaaaat tccagatttt gcttgaagat attcttgaaa
    20581 aggactatga tttgatttgt ttccaagaaa tcaatcagga gatgacctcg tcagaggtgg
    20641 aggttaatga cctttatcaa gctttgccag cagctgagcc tattcaccaa gaccattatg
    20701 ttagactctt ggttgaaaag ttgttagagc aagggaaaaa ttactactgg acctgggctt
    20761 ataaccatat cggctataac cgctaccacg aaggtgtggc tatcttgtct aaaacaccta
    20821 ttgaagccag agaaattttg gtttcagatg tggatgatcc aacagactat catactcgcc
    20881 gtgttgccct agctgaaact gtagtcgatg gcaaggagct agcagttgcc agtgttcatc
    20941 tctcttggtg ggataaaggt ttccaagaag aatgggcacg atttgaggct gtcttgaaaa
    21001 aattgaacaa gccactttta ctagctggag attttaacaa cccagcaggt caggaaggtt
    21061 accaagctat tttagctagt ccattaggct tacaagacgc atttgaagtt gctcaagaga
    21121 aaagtggtag ctatactgtt ccgcctgaaa ttgatggctg gaaagggaac actgaacccc
    21181 ttcgaatcga ttatgtcttt actaccaaag agttagcggt ggaaaattta catgtcgtat
    21241 ttgatggtaa caagagtcca caagtgagtg atcactatgg cttgaatgct atgttaaact
    21301 ggaaataata actgaaaaga ggttggaact ataaaattcc agccttttct tactagagaa
    21361 gctactggaa atagcctaaa taagtgagac tactgtaatg gaataaaata tggtataatt
    21421 gataagatag atagaatcga ggatgttatg tcatttacga aatttcaatt taaaaactat
    21481 attagagaag ccttggagga gttaaaattt acaactccaa cagaggtgca agacaagttg
    21541 attcctattg ttttggcagg tcgtgaccta gtaggagaat caaaaacagg ttcaggtaag
    21601 actcatactt tcttgttacc gattttccag caattagatg aagctagcga tagtgtacaa
    21661 gcagtgatta ctgcaccgag tcgtgagttg gctactcaaa tttaccaagt agcgcgtcag
    21721 atttcagctc actcagatgt cgaagttcgt gtggttaatt atgtgggtgg tacggataag
    21781 gctcgccaga ttgagaaatt ggaaagcaat cagcctcata ttgttattgg aacaccaggc
    21841 cgtatctacg acttggttaa atctggtgat ttagctattc ataaagccaa gacatttgtt
    21901 gttgatgaag cagatatgac cttggatatg ggattcttgg aaattgttga taagattgct
    21961 ggcagtcttc caaaagactt gcaattcatg gtcttctcag cgactatccc acaaaaactg
    22021 caaccattct tgaaaaaata cttatcaaat cctgttatgg agaaaattaa gactaaaacg
    22081 gttatttctg acaccattga taattggttg atttcgacca agggacatga taggaatgct
    22141 caaatttacc aattgactca gttgatgcag ccgtatttgg caatgatttt tgttaacact
    22201 aaaacgcgtg ctgatgaatt gcattcatat ctgactgctc aaggcttgaa ggttgcaaaa
    22261 atccatggag atattgcccc tcgtgaacgc aagcgaatca tgaatcaggt gcaaaatctg
    22321 gattttgagt atattgtcgc aacagattta gcagcgcgtg ggattgacat tgaaggtgtc
    22381 agccatgtca tcaatgatgc cattccgcaa gacttatctt tttttgttca ccgtgttggt
    22441 cgtactggac gaaatggcct accaggtaca gctattaccc tttatcagcc aagtgatgac
    22501 tcggatatcc gtgagttgga gaaattggga atcaagttta gtcctaagat ggtcaaagat
    22561 ggggaatttc aagataccta tgaccgtgat cgtcgtgcca accgtgagaa aaaacaagat
    22621 aaacttgata tcgaaatgat tggtttggtt aaaaagaaaa agaaaaaagt caaaccgggt
    22681 tataagaaga aaattcaatg ggcggttgat gaaaagcgcc gtaaaactaa gcgtgctgaa
    22741 aatcgcgctc gcggtcgtgc agagcgtaaa gctaaacgcc aaacatttta atagaaattg
    22801 ttggagtact gagctccaac ttttttattt atgagaacga actatctaaa ccgaaacact
    22861 acattaaaga ctgcaaattg cgattaaaaa tggtataatg ataaagttat atagtcccga
    22921 taagatggta ggtatttatt acgaagagtt ttcctatcag tagtttgcaa ttcgcaaaga
    22981 atgacggctt cgaggttgct cgtctttcta cggttgccgc catactgcgg tcaccctatg
    23041 cgccttacta gcttcagaaa taaaaaagta tcgtttttat ttctgaagct agtaactctt
    23101 agataatgga aattcctatc agtactttgt aactctataa caatattttt taagggggga
    23161 catttttatg tcagaacgta aattattcac gtctgaatct gtatctgagg ggcatccgga
    23221 taagattgca gaccaaattt cagatgcgat tttggatgct attttagcaa aggatccaga
    23281 ggcgcacgtt gctgctgaaa cagctgtata tactggttct gtccacgttt ttggtgaaat
    23341 ttctacaaat gcctatgtgg atattaaccg tgtggttcgt gataccattg cagagattgg
    23401 ttataccaat acagaatatg gattttctgc tgagacggtg ggagtacacc catctttggt
    23461 ggaacaatct cctgacatcg ctcaaggtgt taacgaagcc ttggaggttc gtggaaatgc
    23521 tgatcaagat ccactggact tgattggagc aggtgaccaa gggctcatgt ttggatttgc
    23581 agtagatgaa acagaagagc tcatgccatt gccaattgca ctcagtcata aattggttcg
    23641 tcgtctggca gaacttcgta agtctggaga aattagctat ctccgtccag atgcaaaatc
    23701 acaagttaca gttgagtacg atgaaaatga ccgtccggta cgtgtagata cagtcgttat
    23761 ttctactcag catgatccag aggccactaa tgaacaaatc catcaagatg tgattaacaa
    23821 ggtcatcaaa gaagttattc catcttctta tcttgatgat aagacaaaat tctttatcaa
    23881 tccgacaggt cgttttgtaa tcggtggtcc tcaaggggac tcaggtttga ctggtcgtaa
    23941 gattattgta gatacttatg gtggctactc tcgtcatggt ggtggtgcct tctctggtaa
    24001 agatgcgact aaggtggatc gttcagcctc ttatgcggct cgctatattg ccaagaatat
    24061 cgttgcagca ggccttgcta agaaggcaga agtgcagttg gcctatgcta tcggtgttgc
    24121 gcaacctgtt tctgttcgta tcgatacttt cggtacagga acagtagctg aaagtcaact
    24181 tgaaaaagcg gctcgtcaaa tctttgacct tcgccctgca gggattatcc aaatgctgga
    24241 cctcaagcgt ccaatttacc gtcaaacatc ggcttacggt cacatgggac gtacagatat
    24301 tgatcttcca tgggaacgtt tggataaggt agatgctttg aaagaagcag taaaataaga
    24361 ttttaagagg ggaacgtcct ctctttttta tagtttttaa ctatactggg atactgttct
    24421 gaaaatccat tttgcgaaag tagagattta catgtatagt agattgaaac tagaatagta
    24481 cacctcaact tctaaaacat tgttagaaat cgatttgact gtcctgatcg atttctcctg
    24541 ttcttgtttc attttactat atttctttaa aaatgataaa ggttgagatt tctcctcgta
    24601 atagataatc atggggatat ttcaatccaa agttttattc gttatcactt gactattgca
    24661 aggttttcta gagcaacaga gtcatggaat ggactcatgg ttgagatttc tccttgttgc
    24721 ttggacttca ttcaaaagtc tgttacccaa gccttgttca aacttccaat acactagctg
    24781 tttccatagc atgacttctg tactagactt tcttttccga ataaatagat agaaccacag
    24841 aatctagtaa acctagaatt aaaattatgg tataatatta gcaataaaag aaatctggag
    24901 gattagaatc atggtatcaa cgaaaacaca aattgctggt tttgagtttg acaattgctt
    24961 gatgaatgca gcaggtgtgg cttgtatgac gatagaggag ttagaagagg tcaaaaactc
    25021 agcggcagga acctttgtta ctaagacagc gaccttggac ttccgtcagg ggaatcctga
    25081 gccacgctac caagatgttc cacttggttc catcaactct atgggcttgc caaataatgg
    25141 cttagactat tatttggatt atcttttaga tttgcaggaa aaagagtcga accgaacttt
    25201 cttcttatct ctggtcggca tgtctccaga ggaaacccat actattttga aaaaagtcca
    25261 agagagtgat tttcgtggtc tgactgagct aaatctttcc tgtccaaatg ttccaggtaa
    25321 acctcagatt gcctatgatt ttgagacaac agaccggatt ttggcagaag tgtttgctta
    25381 cttcaccaaa cctcttggaa ttaaattgcc accttatttt gatattgttc actttgacca
    25441 agcggcagct attttcaaca aatatccgct caagtttgtc aactgcgtta actctatcgg
    25501 aaacggcctc tatatagaag acgaatctgt cgttattcgg cctaagaatg gttttggtgg
    25561 aattggtgga gaatacatca aaccgactgc tctagccaat gttcacgcct tttatcaacg
    25621 tttaaatcct caaatccaaa ttatcggaac aggtggcgtt ctgactggtc gagatgcctt
    25681 tgaacacatc ctctgtggag caagtatggt gcaggtggga acgacccttc acaaagaagg
    25741 cgtcagtgct tttgaccgca ttaccaatga actgaaagca atcatggtgg aaaaaggcta
    25801 cgagagctta gaagatttcc gtgggaaatt gcgctatatt gactaaatta aatcgaaaaa
    25861 tcagaagaaa gaagggacga tgctagccat tgaagaaagt cagaagttga ctttatcaaa
    25921 tttaccgagc ctgagcctat ttacagggac agatcagggt cagtttgaag tgatgaagag
    25981 tcaaatgttg aaacagattg ggtatgattc tgctgacctc aactttgcct actttgatat
    26041 gaaagaagta gtttacaagg atgtggaact ggagttggtc agccttcctt tctttgcgga
    26101 tgagaaaatc gtgatattag attattttat ggatatcacg actgctaaga aacgcttttt
    26161 gacagatgat gagcttaagt catttgagga ataccttgac aatccttctc caacaaccaa
    26221 gttgataatc tttgcagaag gaaagctgga tagcaaaaga cggttagtca aattacttaa
    26281 gcgtgatgcc aaggtcttcg atgcagtaga agtaaaagaa caagaattgc gccagtattt
    26341 ccaaaagtgg agtcagaaac aaggtctgca gtttaccaat cattcttttg aaaatctcct
    26401 catcaagtcg gggtttcaat ttagcgaaat ccagaaaaat cttctctttt tacagtccta
    26461 taaggcgaat tctgttatcg aggaagagga tattgttaac gcaattccca agaccttgca
    26521 ggacaatatt tttgatttaa ctcagtttat tctgactaaa aagatggatc aggcgcgcga
    26581 tttagtgaga gacttgacct tgcaagggga agatgaaatc aaactgattg cagtcatgct
    26641 gggacaattt cggactttta ctcaggtgaa gattttggcg gagtctggcc aaacagaatc
    26701 gcagattgca agtagtttag gtagttatct gggacgtaac ccaaatcctt atcaaatcaa
    26761 gtttgcatta agagattcga gaggactttc tttgagcttt ctgaagcaag ctatttccta
    26821 tttgattgag acagactatc agattaagac aggtctttat gaaaaaggtt tcctttttga
    26881 aaaggcactc ttacagattg ctagtcaggt caattgacat ttgttgaaac tacaacccgc
    26941 gtcaggatta tcttgtcgtg ggtttcttgc tgatttgctt attttattag aaagtatatc
    27001 agtgatttcc ttatctataa gcaaaaaact tgaaaaaagt gaatgtttgc gttatcattt
    27061 tcatatagaa agaaaaagag gtattacaga tggctattat cttaccagaa cttccatatg
    27121 catacgacgc tttggaacca tacatcgatg cggaaacaat gcatttgcac catgacaaac
    27181 accatcaaac ttatgtcaac aatgccaatg cagctttaga aaaacaccct gaaatcggtg
    27241 aagaccttga agccttgctt gctgatgtag aatctatccc agctgatatc cgtcaagcac
    27301 ttatcaacaa tggtggcgga cacttgaacc acgctctttt ctgggaattg atgactcccg
    27361 agaaaacagc tccttcagca gaactggcag cagcaatcga tgcaacattt ggttcatttg
    27421 aagaattcca agcagccttc actgcagcag caacaactcg ttttggttca ggttgggcat
    27481 ggttggttgt caacaaagaa gggaaacttg aagtgacttc aacagcaaac caagacacac
    27541 caatctcaga aggtaaaaaa ccaatcttgg gcttggacgt ttgggaacat gcttactacg
    27601 tgaaataccg caacgtgcgt cctgactaca tcaaagcttt cttttcagta atcaactgga
    27661 ataaagtaga tgaattgtac gcagctgcta aataatgata gttggaggga agaattgttc
    27721 ttctcttttt taggttataa gattctggtc tgacaaaatc gtcagacttt tttcattttt
    27781 atgagaaacg tgctaactgc tagaaattat ggtagaataa agtattaagt aatcgtggaa
    27841 aaaggatatc tatgcgaaaa gaaattgcac ctgaattata caattataac aagtttcctg
    27901 gtccggagtt ccatttacac ggggacaagg tcgaaacgga agggatagct ttttccttgg
    27961 ttgaaaatat caaggatgcc tttgatgtga cgacttttaa tcagcgtttt tcagaagtct
    28021 taaccaagtt tgattatatc gtgggggact ggagcaacga acagcttcgc ctacgaggtt
    28081 tttacaagga tgaccgaaca gaagaaaaac ttgaaaaaat cagtcgttta caagactacc
    28141 ttttagagta ttgtagttat ggttgtgcct attttgtctt agaaaatgaa gcccctaagc
    28201 gagcatcatt tgacaagaaa atgcgtaaga cggaagaaga aacaccttct agaaaaggaa
    28261 agaaaccgac tcaaactaaa cgaaagtcga atgcagataa gaaaaataga cgtcgtcaga
    28321 aagaccagca ttctcagaaa gaggacaagg gacaacgtca ttttgtcatt cgtcagaagt
    28381 gagtagagaa taaggagaag aaatgaaacc ctcaattcat agtttggtac atcaaaccat
    28441 gcaggaatgg gtattggagc agggagaaaa gaaattccgt gcagatcaaa tctgggaatg
    28501 gctctaccgt aaacgtgtgc agtcatttga agaaatgacc aacctttcca aggatttgat
    28561 tgctaagctc aatgaccagt ttgtggtcaa tcccttgaaa caacgtattg tgcaagagtc
    28621 tgctgatggt acagtcaaat atctctttga attgcccgac ggtatgttaa ttgagactgt
    28681 actcatgcgt caacactatg gtttatctgt ctgtgtgacc actcaggtcg gctgtaatat
    28741 cggttgtacc ttctgtgcct ctggtttgat taagaagcag cgtgacctca ataacggtga
    28801 aatcgtagcg caaatcatgc tggttcagaa atactttgat gagcgtggtc aggatgaacg
    28861 catcagccat atcgttgtca tgggaatcgg tgagcccttt gataattaca acaatgtctt
    28921 gaatttcgtt tgtactatca atgatgataa aggaatggct atcggtgctc gtcacatcac
    28981 gatttcaacc tcaggtttgg ctcataaaat tcgtgacttt gctgatgaag gggttcaggt
    29041 caatcttgcc gtgtctcttc acgcacccaa caatgaactt cgttcaagta tcatgaaaat
    29101 taaccgtgcc tttccgattg aaaaactctt tgctgctatt gaatactata ttgagacaac
    29161 aaaccgtcgt gtaacctttg aatatatcat gcttaatgaa gtcaacgacg gtgtagaaca
    29221 agccttggaa ttggctgaat tgctcaagaa catcaagaaa ttgtcttatg taaacttgat
    29281 tccttataac ccagttagtg agcatgacca atatagccgt agtcccaaag agcgcgtgtt
    29341 ggctttctat gatacgctta agaaaaaagg ggtcaactgt gtggttcgtc aagagcatgg
    29401 tacagatatt gacgcagctt gtggacaatt gcgctctaac acaatgaaac gtgaccgcca
    29461 gaaggcagtc gcagcggtaa atccttaatg atgaagaaga cttataatca tattttggtc
    29521 tggggagtca ttttctatag catttgcatt gtctgttttt gctttactcc tcaagaacaa
    29581 tctaccgtgg gagtgggaac tccaggtatt cagcatcttg gacgcctggt ttttcttttg
    29641 actcctttca attctctctg gaaactgggc gaagtgagtg acattggaca attatgttgg
    29701 atttttttac aaaatatcct caatgtcttc ttgttttttc ctctgatttt ccaactcctt
    29761 tatctatttc caaatttgcg gaaaacaaaa aaggtccttc tttttagttt tcttgtgagt
    29821 cttggaatcg agtgtacgca attaatcttg gactttttct ttgatttcaa tcgcgtcttt
    29881 gagattgatg atttgtggac caacactttg ggtggctatc tggcttggct cctttataaa
    29941 cgattacata aaaacaaggt aaggaattaa aatgagtatt ttagaagtta aaaatctgag
    30001 tcacggtttt ggtgaccgtg caatttttga agatgtgtcc ttccgtctcc tcaagggaga
    30061 acatatcggc ctggtcggtg ccaatggtga aggaaaatca acctttatga gtatcgtgac
    30121 tggtaaaatg ctgccagatg aaggaaaggt tgagtggtcc aaatatgtga cggctggtta
    30181 cttggatcag cactctgtcc ttgctgaaag acagtcggtg cgtgatgttc tccgtacggc
    30241 ttttgatgag cttttcaaag ctgaagctcg tatcaatgac ctctatatga aaatggctga
    30301 agacggcgcg gatgttgatg ctctcatgga agaagtagga gaacttcaag accgtctgga
    30361 gagtcgtgat ttctatacct tggatgctaa gattgacgaa gtagcgcgtg ctcttggtgt
    30421 tatggacttt gggatggata cggatgtaac ttctttgtca ggtgggcaaa gaaccaaggt
    30481 gcttttggca aaacttctcc ttgaaaagcc tgatattttg ctgttggacg agccgaccaa
    30541 ctacttggat gctgagcata ttgattggct caagcgctat ctccaaaact atgagaatgc
    30601 ctttgttctt atttcgcacg atattccatt cctcaatgac gttattaata ttgtctatca
    30661 tgtggaaaat caacagctga cgcgttactc tggtgactac taccagttcc aagaagttta
    30721 tgctatgaag aaatctcagc tagaggcagc ctacgaacgc cagcagaaag agattgcaga
    30781 cctcaaggac tttgtggctc gtaataaagc ccgtgttgca actcgtaata tggctatgtc
    30841 tcgtcaaaag aaattggata agatggatat tatcgaactc caaagtgaga aaccaaaacc
    30901 atcctttgat ttcaaaccag ctcgtacacc agggcgcttt atcttccaag ccaagaactt
    30961 gcaaattggt tacgaccgtc ctcttactaa gcctttaaat cttaccttcg aacgcaatca
    31021 aaaggttgcg attattggtg ctaatggtat tggaaaaaca actctcttga agagtctctt
    31081 aggcattatc tcgccaatcg ctggggaagt ggagcgtgga gattatttag aacttggtta
    31141 ttttgagcag gaagtagaag gcggtaatcg ccaaactcct cttgaagctg tctggaatgc
    31201 ctttcctgcc cttaatcaag cagaagtccg tgcagccctt gcccgttgtg gtttgacaac
    31261 caaacatatt gaaagccaga ttcaagtatt atcaggggga gagcaagcca aggttcgttt
    31321 ctgtctcttg atgaatcgtg aaaacaacgt tttagtgctg gacgagccga ccaaccattt
    31381 ggatgtggat gcaaaggatg agctcaaacg cgctctcaaa gaatacaggg gatctatcct
    31441 tatggtctgc cacgagccag acttttatga aggttggata gaccaaatat gggattttaa
    31501 taatttaact taagaatgag agtaaaagaa atacagtacc gaatgtggat actgtatttt
    31561 tttggttttt aagatttaaa atcgtagtct ttcaccactt cgatgctgtc gattgtgata
    31621 gcagtagttg gcttgtcttt ttcatctttt tcggctttag caatcttatc cacaacatcc
    31681 ataccgtcaa tcacttgacc aaagactggg tgtttgccat ctagactagg gtttccacct
    31741 tctttgtagg cttcgataat tttctgtgga tacttgcttg tagggagttt agaagaggta
    31801 tctgtagagt tttggttgat gaagaactgg ctgccattgg tgtttggttg accagtatta
    31861 gccatagcaa gagcaccacg gatgttatac aaataaggag taatctcgtt cttgaaacca
    31921 gttcctttgt ctttagtctt atccttgtca tgccatatgg actgaccacc tgtaccgtcc
    31981 ccttttggat ctccagtttg gaccataaag ccatcgatga cacggtggaa ggtaataccg
    32041 ttatagtagc cttctttggc gtgagtgagg aaattttcaa ccgctagagg agcgagttta
    32101 gggaagagtt taatgcgaat atcaccttgg cttgtgtgga gaatcacttc ggcttcatct
    32161 tcagcaactt ccttagatag ttgtgggaaa ttggcgtttt cgtttgttaa agcatcgttt
    32221 aactccttgg cagattgggc agctactttg gaactttctt cagcagcaag actggaatca
    32281 acataatcat caccacgcag actgcgttgg acgctgctac acccagctag ggctacagta
    32341 gacagtaaaa gaagggttgc tagttttttc attctgatcc tctcaaaaat tcatttatac
    32401 cattgtaccc taaaaggaag tggatttcaa atattagtag tttacagaac tggcttagat
    32461 aatagttggg atttcatcat catcttgaaa atcttcaact tcttcaactt cttccccagt
    32521 aaatggtttc tgaaaagaac ttagtataaa acgggcaatt ggttcaacaa ttaggaaatt
    32581 tagaggaaga gctgcaataa agtttacgaa ccaggcgctt agataggtat tgggtgtgat
    32641 agcaatgcca ttgtaaaaaa gtccatagaa ggacatgaaa gtgaccagct aattcttctt
    32701 ctgaaaaatg ctcatgaagg gcttgatcca ggtcgcaaga tttcatttta gaaagtccag
    32761 taactccctt cttcttcagg atattctttt tcatggtatt atttagatgg tcaagtgagt
    32821 caaaagaagt ttcgacaaga gcataccctt tttctaccag agtttttaga tgtttagggg
    32881 catcaatacc ataagtgtac tcaaagtatt ttggaaacca gatcttaaga aagctcgtaa
    32941 agctagccag ttctctaaac gctaagaact agctacaaca cagcatttac aacacttcat
    33001 ggttcacacc atggggtgtt ttttaatgat tttaagcaaa attcacactt aattgaaagt
    33061 tatttaaatt agatgaaaat ttattttttg aaaaagtggg aaaacattga ttctaagcga
    33121 attttgaatc atattcgaat gggagttttt aaaatcatgt ttcagtggta aaagtaccaa
    33181 actggattct ccatagtaaa atgatatctc ctgctagtga atcatctgct aataagtcca
    33241 tatttcgctt gggacttaga agccaagtat ccaactctcg ttcaggcgat atgaagggtt
    33301 tgacttggtg ttctttataa aatttttcta aaatagtatt cacggatagc atctttcaaa
    33361 catttatttc ctattctaac aaatttctaa atgctttaag aaatttatag tctgtcaagt
    33421 ttttttcttg acacctgcca gaaatctgct ataatagaac atgtgctaaa tagctcagct
    33481 atttcaccga aataaaaaat taaagaaatg agactttaaa aatggcagtt aaaatccgtt
    33541 tgactcgtat gggttctaag aaaaaacctt tctaccgtat caacgtagca gattcacgtt
    33601 caccacgtga cggacgtttc atcgaaacag ttggaactta caacccactt gttgctgaaa
    33661 accaagtaac tttgaaagaa gaccgcgttc ttgcatggtt ggctaatgga gctcaacctt
    33721 cagacacagt acgtaacatc ctttcaaaag aaggcgtatt gaaaaaattc cacgattcta
    33781 aattctcaaa ataagtttaa agtaggttga cagatggata cgattgaaaa tctcattatt
    33841 gcgattgtga aacccttaat ttcacaacca gatgccttaa ctatcaagat tgaggataca
    33901 ccagaatttt tggaatatca tttgaatctt gatcaaagcg atgtgggtcg tgtaatcggt
    33961 cgtaagggtc gcactatttc tgcgataaga acgattgtct actctgtccc aactgaatac
    34021 aaaaaagtaa gaatcgttat tgacgaaaaa taagaagggc gggacggatg tctcgctttt
    34081 ttgtgtggaa tagaagatat agtaaaatga aataataaca ggacaaatcg atcaggacag
    34141 tcaaatcgat ttctaacaat gttttagaag taaaggtgta ctattctagt ttcaatatac
    34201 tataaaagat tgaacgttta ggcaattcca agactactta atcgaacatt aacagcagtc
    34261 tcggactgat gaaggtcttt ttatgaagtt agtggaggaa gtcggagaag tagccgaggt
    34321 tttgaatagg cgctctggtc gaaaagaagg gataggattc gaacgaggaa cttgccagag
    34381 aactggctga tatcatttac tacaccgtcg caatcgtagc tattaatcat attgacctta
    34441 ccaagactgt ctttgagaaa gacaaaaccg cagccgttaa ttaccaacat aaacataatt
    34501 tggaaggatt attgaaggga aagtagagat attgtcccct tcctccaact tgagaaaatc
    34561 cttggaacgt gataaaataa aggataagga tttttaataa ttcattatat agaatcagtg
    34621 gatttcttta tgaagaggtt tgaagtatct acagaaattg gtagcctctc tgttacttat
    34681 caaaagcaaa agaaagtgct agtttgtcta aacggagcag gtttgctacc aagttatgaa
    34741 aatttttcac ttatacttga aaaacctcct cctacaattg gttatttgac aattgatttt
    34801 ccgaacacag gtaggagtcc gattcatgac caagctggaa aaaatctaga taatcttgca
    34861 gatgcggttt atgaagtact tgaagaatta ggaatttctg aatatatact ttgtgcacat
    34921 agttggagtg gaattttagc ttgcaaatta ctcgagaaac caattaagcg tcagacttta
    34981 gtagcaattg aaccgacaac taaaaaagtc atgtttgctg atttttcaga aaatccttat
    35041 ccagaaatgg aagagcagat gaggctgatt gacgagtgtg gtcctgaact ttattttaag
    35101 aacttaactc aagcaacatt tagtcctgaa acgaataaaa aaatctggga attaatgcaa
    35161 gaaaaaggct tagagttgga aaatcaagat ccagaatttc agatatctgg agagattact
    35221 gaggaagatt ttgaggatgt atctatagaa gctcatattc ctgtatttgt tttttgtcag
    35281 ccttatagag aaaaagagta cagagaatca gaatattgga cttccaatac taaactcatt
    35341 ttaggaggga atcaccatta tttacaatgg tcagaatcgg aaaaaattgc ggctattatt
    35401 cgagaattgt tagaataaga tggaaaaaag gagattacag gagacaagat gaactacttt
    35461 aatgttggga aaatcgttaa tacgcaggga ttacagggtg agatgcgagt cttgtctgtg
    35521 acggattttg cagaagaacg gtttaaaaaa ggagctgagc tggctttgtt tgatgaaaaa
    35581 gatcagtttg tccaaacagt gaccatcgct agccaccgta aacagaagaa ctttgacatt
    35641 attaaattca aagatatgta ccatatcaat actatcgaaa agtacaaggg atacagtctc
    35701 aaggtcgctg aggaagattt gaatgaccta gacgatggtg aattttacta tcacgagatt
    35761 atcggtttgg aagtctatga gggtgatagc ttggttggaa ccatcaagga aatcctgcaa
    35821 ccaggtgcta atgatgtctg ggtggtcaaa cgaaaaggca aacgtgattt gcttttacct
    35881 tatatcccac cagtggttct caatgttgat attccaaata aacgggtcga tgtggaaatc
    35941 ttagaagggt tagacgatga agattgatat tttaaccctc tttccagaga tgttttctcc
    36001 actggagcac tcaatcgttg gaaaggctcg agaaaaaggg ctcttggata tccagtatca
    36061 taattttcga gaaaatgctg aaaaggcccg tcatgtagat gatgagccct acggaggcgg
    36121 tcagggcatg ttgctcagag tacaacctat tttcgattcc tttgatgcta ttgaaaagaa
    36181 aaatccgcgc gttattctcc tcgatcctgc tggaaagcag tttgatcagg cttatgctga
    36241 agatttggct caagaggaag agctaatctt tatctgtggg cactatgagg gttatgatga
    36301 gcgcattaag accttggtaa cagatgagat ttccctaggc gactatgtcc tcactggtgg
    36361 agaattggca gctatgacca tgattgatgc tacagttcgc ctgattccag aagtgattgg
    36421 caaggagtct agccaccaag atgatagttt ttcttcaggt cttttagaat atcctcagta
    36481 cacacgtcct tatgattatc gaggcatggt cgtgccagat gtattgatga gtggccacca
    36541 tgaaaagatt cgtcagtggc gattgtacga gagtttaaag aaaacctacg agcgcagacc
    36601 ggatttactt gaacattatc aactgacagt agaagaagaa aaaatgctgg cagaaatcaa
    36661 agaaaacaaa gaataaagga gaaacctatg caagtaatca aacgtaatgg cgaaattgct
    36721 gaatttaatc cagataagat ttaccaagcc atcttgaagg cagcccaaac tgtttatgtt
    36781 ttgacagatg atttgcgtca aaatcttgct caagtcacta agaaggtagt tttggattta
    36841 caagaagcca aggtggaacg tgcgactatc agtatgattc aatctatggt tgaacatcgt
    36901 ttattgggcg caggttacat taccattgca gaacactaca tttcctatcg tttacaacgt
    36961 gacttggaaa gaagtggtta tggagatcat atcgcagttc atttacattt tgaacaaatt
    37021 cgctaagaaa aaagagtggg atgaagcaac tacatctcac tctttcttaa atctattttt
    37081 ttgggctgtt tggacagttg aggggacaaa tcgcaggcgt tgaatatcgc ttatacggat
    37141 aatccggctc acatttttgg aaaaattttt cacgataatt tgctggcctt gctgatcata
    37201 tttgatgatg tcacctgtaa agcttgtctc agataagata aggtgaacag cggtttgttt
    37261 ctggatagcc tcttcaatag tggctgtaag ggagttggtt tcagtctggt caggttggtc
    37321 atatccattt aaaaaatcat gtattttatt tagaacttgc tggaatttat gtctcatatt
    37381 ggcctccctt cttttatatc aatattatat aaaattttcc taaaatctac aagattttac
    37441 gaataaacta atgaaactaa aaaaggagaa gaaaatggca gaatttacat ttgaaatcga
    37501 agagcacttg ttgactcttt ctgaaaacga aaaaggttgg accaaggaaa ttaaccgtgt
    37561 gagctttaat ggtgcccctg caaagtttga tattcgtgct tggagtccag accatactaa
    37621 aatgggcaaa gggattactc tctcaaatga agaatttcaa acgatggtgg atgcctttaa
    37681 aggcaactaa tactcttcga aaatctcttc aaaccgcgtc agctttgcct tgccgtatgt
    37741 atggttactg acttcgtcag tttcatccac aacctcaaaa caatgttttg agctgacttc
    37801 gtcagtttca tccacaacct caaaacaatg ttttgagctg acttcgtcag tttcatccac
    37861 aacctcaaaa cagtgttttg agcagcctgc ggctagcttc ctagtttgct ctttgatttt
    37921 cattgagtat aagttttcaa aataaaagaa aaggatattg agtcatgata actcggtatc
    37981 cttttttagt tagtaaagta agcctgattt ttaaggcgtt gaagtagggg acggctaata
    38041 aaactaatag ccagaagttt gccaaggtct ggaatgataa agggaagaac ccccacaaca
    38101 agagcttttt caaatgccat tccagctagg aaatgcaagc tgagaatccc gccgacaaag
    38161 acaagggcat cacccaagag gtttgcaaga aaaatcttaa caacaccact cttgctgttg
    38221 gttagagagg aagtaagtcc agagtaaacg agataaaacc aaagatagcc tgcagtaggg
    38281 ccaactaaag cctgaaaacc agctccacct cctgcaaaga caggaagacc gatagcacct
    38341 agaagaagat agagtccagc agaaagtaca gcctctctcg gtctaaagac agtagcaatc
    38401 aagccgattg caaagttttg cagagtgaag ggaacaggtc caattggaag actgatttgt
    38461 gccaaagcag caatgagagc agccccaata gcagggatag cataaacgtg agcttttttc
    38521 aaaatagtta acctcttttc taatgtatag taactattat actcatatag gagtcgatgt
    38581 caaccatttt ttaaaaacaa ggtaacaaaa actgtaacag ccgattttcg tgactagtca
    38641 agttggataa tttttttgtt gattcgaaaa tcattaaaaa agaagcagac atatttatat
    38701 cagcttcttt tgtttcgatt aacgcatggt tacaaattct tcagatgcag ttgggtgaat
    38761 tgccacagtt gcatcaaagt cagccttggt tgctcccatt ttgatagcaa cggcaaatcc
    38821 ctgaatcatt tcatcaacgc cgtagccaat tccatgaagt ccgacaactt tttcttctga
    38881 accagctgtt atgagtttga aacgggattc ttgacggttg cgagtgcaag cagagtacat
    38941 agatgcaaag cttgatttat aaaccttgat ttggtcttga ccgtattctt taatagcttg
    39001 ctcttctgtc aaaccaacag ttccgatagc agggtgtgaa aagacaacag ttggaatagt
    39061 tgagtaatcc atttttgcag tagtttttcc gttaaagaga cgttcagata gggtacgtcc
    39121 ggccttgatt gcaactggag tcagttcttt ctcgcccgtt acatcaccta gagcatagag
    39181 tccctcaaca acagtatttt ggtattcatc cacttggata aagccacgtt cgttcagagt
    39241 cactccagct ttttcaagtt gcaagccctt aacgtttgga cggcggcctg tagcccagat
    39301 aacttggcta gctgtgtgac tagtaccatc ttcgaaatga atggtaatgc cgtcagtagt
    39361 tttttctaac ttgacaggga ctttgtgagt gtgaagtggt aagtttgttc tttccatttc
    39421 cttgaccaaa ccttcaacga tgtaggaatc aaaaccacgt aaaggacgat cgcggcgaac
    39481 aaagagatct gtcttgacac caaaagtgtg gagtacgcca gctaattcaa cggcgatata
    39541 accagcgcct agaatggcaa ctgactctgg aagttcttcc caggcaaata catcatcaga
    39601 agagccacct agctcagcac caggaatatt aggaatactt ggatgggcac ctgtagcaat
    39661 cacgatatgt ttagcacgaa tcagttcacc atttacgctt acagtatgag aatctacaaa
    39721 ttcagcatga ccttcaatca agtctacacc gttgcgttta aaactaccat cataagaaga
    39781 acgagcgcga tcaatgtagg cttcacgatt gcgacgtagg gttgcaaagt caaagttaag
    39841 atcagtagtc ttaaagccgt agtcttctcc aaattgatgg aaagtctcag cgatttgcgc
    39901 cccgtaccac atgatttttt taggaacaca accgacgttg acacaggttc cacctaattt
    39961 cttttcctca ataacggctg ctttggctcc atgttcacca gcacggttca tggtagcgat
    40021 tcctccgcta cctccaccga tagcaatgat atcatattct ctcattgaaa actcctttgt
    40081 aatcttttaa atagtagagc gtcttttttg atagttatat tttattcttt ttttgatttg
    40141 attgcaaaaa tctgctacgc acaaaaaatt gcaaaaaagc ttgccaaata agtcaagata
    40201 gtgtattata tatctagtac aatagaaaag caaaattccg aacgattgtt taatcctgaa
    40261 ctgccattat ttccatctga actgcattgt ttgctggagg gaaatttggt ataatagcaa
    40321 agtattgtaa aaaagaaaag gagtttcatt atgaagaaaa agaatggtaa agctaaaaag
    40381 tggcaactgt atgcagcaat cggtgctgcg agtgtagttg tattgggtgc cggggggatt
    40441 ttacttttta gacaaccttc tcagactgct ctaaaagatg agcctactca tcttgttgtt
    40501 gccaaggaag gaagcgtggc atcctctgtt ttattgtcag ggacagtaac agcaaaaaat
    40561 gaacaatatg tttattttga tgctagtaag ggtgatttag atgaaatcct tgtttctgtg
    40621 ggcgataagg tcagcgaagg gcaggcttta gtcaagtaca gtagttcaga agcgcaggcg
    40681 gcctatgatt cagctagtcg agcagtagct agggcagatc gtcatatcaa tgaactcaat
    40741 caagcacgaa atgaagccgc ttcagctccg gctccacagt taccagcgcc agtaggagga
    40801 gaagatgcaa cggtgcaaag cccaactcca gtggctggaa attctgttgc ttctattgat
    40861 gctcaattgg gtgatgcccg tgatgcgcgt gcagatgctg cggcgcaatt aagcaaggct
    40921 caaagtcaat tggatgcaac aactgttctc agtaccctag agggaactgt agtcgaagtc
    40981 aatagcaatg tttctaaatc tccaacaggg gcgagccaag ttatggttca tattgtcagc
    41041 aatgaaaatt tacaagtcaa gggagaattg tctgagtaca atctagccaa cctttctgta
    41101 ggtcaagaag taagctttac ttctaaagtg tatcctgata aaaaatggac tgggaaatta
    41161 agctatattt ctgactatcc taaaaacaat ggtgaagcag ctagtccagc agccgggaat
    41221 aatacaggtt ctaaataccc ttatactatt gatgtgacag gcgaggttgg tgatttgaaa
    41281 caaggttttt ctgtcaacat tgaggttaaa agcaaaacta aggctattct tgttcctgtt
    41341 agcagtctag taatggatga tagtaaaaat tatgtctgga ttgtggatga acaacaaaag
    41401 gctaaaaaag ttgaggtttc attgggaaat gctgacgcag aaaatcaaga aatcacttct
    41461 ggtttaacga acggtgctaa ggtcatcagt aatccaacat cttccttgga agaaggaaaa
    41521 gaggtgaagg ctgatgaagc aactaattag tctaaaaaat atcttcagaa gttaccgtaa
    41581 tggtgaccaa gaactgcagg ttctcaaaaa tatcaatcta gaagtgaatg agggtgaatt
    41641 tgtagccatc atgggaccat ctgggtctgg taagtccact ctgatgaata cgattggcat
    41701 gttggataca ccaaccagtg gagaatatta tcttgaaggt caagaagtgg ctgggctggg
    41761 tgaaaaacaa ctagctaagg tccgtaacca acaaatcggt tttgtctttc agcagttctt
    41821 tcttctatcg aagctcaatg ctctgcaaaa tgtagaattg cccttgattt acgcaggagt
    41881 ttcgtcttca aaacgtcgca agttggctga ggaatattta gacaaggttg aattgacaga
    41941 acgtagtcac catttacctt cagaattatc tggtggtcaa aagcaacgtg tagccattgc
    42001 gcgtgccttg gtaaacaatc cttctattat cctagcggat gaaccgacag gagccttgga
    42061 taccaaaaca ggtaaccaaa ttatgcaatt attggttgat ttgaataaag aaggaaaaac
    42121 cattatcatg gtaacgcatg agcctgagat tgctgcctat gccaaacgtc agattgtcat
    42181 tcgggatggg gtcatttcgt ctgacagtgc tcagttagga aaggaggaaa actaagatgc
    42241 agaatctgaa atttgccttt tcatctatca tggctcacaa gatgcgttct ttgcttacta
    42301 tgattgggat tattatcggt gtttcatcag ttgttgtgat tatggctttg ggtgattccc
    42361 tatctcgtca agtcaataaa gatatgacta aatctcagaa aaatattagc gtcttttttt
    42421 ctcctaaaaa aagtaaagac gggtctttta ctcagaaaca atcagctttt acggtttctg
    42481 gaaaggaaga ggaagttcct gttgaaccgc caaaaccgca agaatcctgg gtccaagagg
    42541 cagctaaact gaagggagtg gatagttact atgtaaccaa ttcaacgaat gccatcttga
    42601 cctatcaaga taaaaaggtt gagaatgcta atttgacagg tggaaacaga acttacatgg
    42661 acgctgttaa gaatgaaatt attgcaggtc gtagtctgag agagcaagat ttcaaagagt
    42721 ttgcaagtgt cattttgcta gatgaggaat tgtccattag tttatttgaa tctcctcaag
    42781 aggctattaa caaggttgta gaagtcaatg gatttagtta ccgggtcatt ggggtttata
    42841 ctagtccgga ggctaaaaga tcaaaaatat atgggtttgg tggcttgcct attactacca
    42901 atatctccct tgctgcgaat tttaatgtag atgaaatagc taatattgtc tttcgagtga
    42961 atgataccag tttaacccca actctgggtc cagaactggc acgaaaaatg acagagcttg
    43021 caggcttaca acagggagaa taccaggtgg cagatgagtc cgttgtattt gcagaaattc
    43081 aacaatcgtt tagttttatg acgacgatta ttagttccat cgcagggatt tctctctttg
    43141 ttggaggaac tggtgtcatg aacatcatgc tggtttcggt gacagagcgc actcgtgaga
    43201 ttggtcttcg taaggctttg ggcgcaacac gtgccaatat tttaattcag tttttgattg
    43261 aatccatgat tttgaccttg ttaggtggct taattggctt gacaattgca agtggtttaa
    43321 ctgccttagc aggtttgtta ctgcaaggtt taatagaagg tatagaagtt ggagtatcaa
    43381 tcccagttgc cctatttagt cttgcagttt cggctagtgt tggtatgatt tttggagtct
    43441 tgccagccaa caaggcatcg aaacttgatc caattgaagc ccttcgttat gaatgagatc
    43501 aacaagatgg acactcgtct atcttgtttt tgtatggatt tccctatcga aattcattaa
    43561 aaatgtgata taatgaagtg ttagaaaaac aggtttcatt tgcctggaaa ggaaaaatta
    43621 tgtctgaaaa aaatttttat attacaacgc cgatttacta tccatctggg aaacttcata
    43681 tcggttctgc ctacacaact atcgcatgtg atgtcctagc acgttacaaa cgcctgatgg
    43741 gctacgatgt attttatctg acaggtcttg atgaacatgg tcagaaaatc cagcagaaag
    43801 cggaagaagc tggtattaca cctcaagcct atgttgatgg aatggcggtt ggagttaaag
    43861 aactctggca attactagat atctcatacg ataaatttat ccgtacaact gatgactacc
    43921 atgaaaaagt tgttgcacag gtctttgaac gcttacttgc tcaagatgat atctacttgg
    43981 gtgaatactc tggttggtat tcagtatcag acgaagaatt ctttacagaa agccagctgg
    44041 cagaagtttt ccgtgatgaa gctggaaatg tgactggtgg tattgctcca tcaggtcatg
    44101 aggttgaatg ggtttctgaa gaatcatact tccttcgcct tagcaaatac caagaccgtt
    44161 tggtcgaatt tttcaaagct catcctgaat ttatcacgcc agatggtcgc cttaatgaaa
    44221 tgctacgcaa cttcatcgag ccaggtttgg aagatttggc ggtatctcgt acaaccttta
    44281 catggggagt gcctgtccca tcaaatccaa aacacgttgt ctacgtttgg attgatgccc
    44341 ttcttaacta tgcgacagct cttggctacg ctcaagacga acatggtaac tttgacaagt
    44401 tctggaatgg aacagtcttc catatggtag gaaaagatat ccttcgcttc cactctatct
    44461 actggccaat ccttcttatg atgttggatg ttaaattacc tgatcgtttg attgcccatg
    44521 gttggtttgt catgaaagac ggaaaaatgt ctaagtcaaa agggaatgtc gtttaccctg
    44581 aaatgttggt agagcgttat ggactagatc cacttcgtta ctacctcatg cgtaaccttc
    44641 cagttggttc agacggaacc tttactcctg aagactatgt cggccgtatc aactatgaat
    44701 tggctaatga ccttgggaac ctccttaacc gtacggtttc catgattaat aagtactttg
    44761 atggacaaat ccctgcctat gtagaaggtg tgactgaatt tgatcatgtt cttgctgagg
    44821 ttgcagaaca atcaatcgca gacttccata cacacatgga agcagttgac tatccacgtg
    44881 cgcttgaagc agtctggact ctgatctctc gtaccaataa atacatcgat gagactgcac
    44941 catgggtctt ggacaaggat gaagctcttc gtgaccaatt ggcaagtgtc atgagccact
    45001 tggcagccag cattcgtgta gttgctcact tgattgaacc atttatgatg gaaactagtc
    45061 gtgcagtttt gactcaactt ggtttggaag aagtttctag tcttgaaaac ttgagtttgg
    45121 ctgacttccc agcagatgtg actgtagttg ccaaaggaac acctatcttt ccacgtctaa
    45181 atatggaaga agaaatcgcc tatatcaagg aacaaatgga aggcaataaa ccagcagtcg
    45241 aaaaagaatg gaatccggac gaagttgagc tcaaactaaa caaggatgaa atcaagtttg
    45301 aagactttga caaggttgaa atccgtgtcg cagaagtcaa agaagtgtct aaagtagaag
    45361 gttcagataa gttgcttcaa ttccgcttgg atgctggtga tggagaagat cgtcagattc
    45421 tttcaggaat tgcaaaatac tatccaaatg aacaagaatt ggtcggcaag aaagttcaaa
    45481 tcgttgctaa cctcaaacca cgtaaaatga tgaaaaaata tgtcagccag ggtatgattc
    45541 tctcagctga acatgatggc aaattaaccc ttctcacagt tgatccagct gtaccaaatg
    45601 gaagtgtgat tgggtaaaag tagacaggac tagttcaggc tagttctgtt tttttattta
    45661 tactcaatga aaatcaaaga gcaaactagg aagctagccg cgggttgatc aaagcactgc
    45721 tttgaggttg tagatgaaac tgacgaagtc agctcaaagc actgctttga ggttgtagat
    45781 gaaactga
//
LOCUS       DAVKMJ010000015        45539 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000015 DAVKMJ010000000
VERSION     DAVKMJ010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45539
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.015"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(1..313)
                     /locus_tag="VW348_000824"
                     /pseudo
     CDS             complement(1..313)
                     /locus_tag="VW348_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(408..593)
                     /locus_tag="VW348_000825"
                     /pseudo
     CDS             complement(408..593)
                     /locus_tag="VW348_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            621..848
                     /locus_tag="VW348_000826"
     CDS             621..848
                     /locus_tag="VW348_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9745756.1"
                     /translation="MRERLLTQPLLHADETSYRVLESHSHLTYYWTFLSGKVENQAIT
                     LYHHDQSRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            924..1476
                     /locus_tag="VW348_000827"
                     /pseudo
     CDS             924..1476
                     /locus_tag="VW348_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2060..2536
                     /locus_tag="VW348_000828"
     CDS             2060..2536
                     /locus_tag="VW348_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9745757.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            2574..2879
                     /locus_tag="VW348_000829"
     CDS             2574..2879
                     /locus_tag="VW348_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9745758.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            2927..4402
                     /locus_tag="VW348_000830"
     CDS             2927..4402
                     /locus_tag="VW348_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEU9745759.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNIVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            4428..4505
                     /locus_tag="VW348_000831"
                     /pseudo
     CDS             4428..4505
                     /locus_tag="VW348_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            4707..11408
                     /locus_tag="VW348_000832"
     CDS             4707..11408
                     /locus_tag="VW348_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEU9745760.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASSQEKPLKEDAKAVTNEEVNQMIENRKVDFNQNWYF
                     KLNANSKEAIKPDADVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLYKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSQ
                     VDVSQAGVVTVKGTANGREVEAHVKVLAIAKELPTVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLNAEYEGAKDQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQEPSLPATVTVEYDKGFPKTHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRPEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     VPKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKSLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEVTVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQGKVQFFA
                     DSGTDAPSKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAIKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSFPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKIEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKVGK
                     ERIFTAINPDGSKEEKLREVVEVPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPSTGSAASQAAVAAGLTLLGLSAGLVVTKGKKED"
     gene            complement(11656..12512)
                     /locus_tag="VW348_000833"
                     /pseudo
     CDS             complement(11656..12512)
                     /locus_tag="VW348_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12722..13081)
                     /locus_tag="VW348_000834"
     CDS             complement(12722..13081)
                     /locus_tag="VW348_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEU9745761.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            13104..13682
                     /locus_tag="VW348_000835"
     CDS             13104..13682
                     /locus_tag="VW348_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846832.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEU9745762.1"
                     /translation="METRNRGIYRKVRLLRLWVIFVIMKVMKSYNTLNDYYRKLFGEK
                     TFKVPIDAGFDCPNRDGTVAHGGCTFCTVSGSGDAIVAPDAPIREQFYKEIDFMHRKW
                     PDVQKYLVYFQNFTNTHEKVEVVRERYEQAINEPGVVGINIGTRPDCLPDETIEYLAE
                     LSECMHVTVELGLQTTYEATSDLINRAHSYEL"
     gene            13683..14129
                     /locus_tag="VW348_000836"
     CDS             13683..14129
                     /locus_tag="VW348_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HEU9745763.1"
                     /translation="METVKRLRKYPKIEIVSHLINGLPGETHEMMVENVRRCVTNNDI
                     QGIKLHLLHLMTNTRMQRDYHEGRLQLMSQDEYVRVICDQLEIIPKHIVIHRITGDAP
                     RDMLLGLMWSLNKWEALNSIEMEMRRRGSVQGCKAVKQEFENEKTT"
     gene            14113..14670
                     /locus_tag="VW348_000837"
     CDS             14113..14670
                     /locus_tag="VW348_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9745764.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQAGLTNAQLILQGHETLDQFVTKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            14663..14917
                     /locus_tag="VW348_000838"
     CDS             14663..14917
                     /locus_tag="VW348_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745765.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            14929..16983
                     /locus_tag="VW348_000839"
     CDS             14929..16983
                     /locus_tag="VW348_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEU9745766.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            17162..18022
                     /locus_tag="VW348_000840"
     CDS             17162..18022
                     /locus_tag="VW348_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEU9745767.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            18233..18943
                     /gene="ccdA2"
                     /locus_tag="VW348_000841"
     CDS             18233..18943
                     /gene="ccdA2"
                     /locus_tag="VW348_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU9745768.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGFLVLFGNASILSQLFE"
     gene            18963..19529
                     /locus_tag="VW348_000842"
     CDS             18963..19529
                     /locus_tag="VW348_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEU9745769.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            19540..20652
                     /gene="msrB"
                     /locus_tag="VW348_000843"
     CDS             19540..20652
                     /gene="msrB"
                     /locus_tag="VW348_000843"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEU9745770.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            21010..21747
                     /locus_tag="VW348_000844"
     CDS             21010..21747
                     /locus_tag="VW348_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9745771.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            21744..23435
                     /locus_tag="VW348_000845"
     CDS             21744..23435
                     /locus_tag="VW348_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9745772.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            23551..24114
                     /locus_tag="VW348_000846"
     CDS             23551..24114
                     /locus_tag="VW348_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEU9745773.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            24136..30078
                     /locus_tag="VW348_000847"
     CDS             24136..30078
                     /locus_tag="VW348_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEU9745774.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAEAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKSEEKVAVKPESQPSDKPAEES
                     KVEQAGEPVAPREDEKAPVEPEKQPEAPEEEKAVEETPKQEDTQPEVVETKDEAANQP
                     VEEPKVETPAVEKQTEPTEEPKVEQVGEPVEPREDEKAPVSPEKQPEAPEEEKTAEET
                     PKQEDKIKGIGTKEPVDKSELNNQIDKASSVSPTDYSTASYNALGPVLETAKGVYASE
                     PVKQPEVNSETKAEKVAANTDAKQSEVNSETASLKTAISGLNTDKVELENQLKIAQGK
                     TETDFSMESWTVLSTAKNKAQEVKDNGTATQEQINEAEKSLKTALADLSVDKTALGSA
                     IDTATKKNKENYTNQTWAELETVLTAAKSVNTNESKQSEVNEAVEKLTATIEKLVELS
                     EKPRLTLSIEKRDIDRKVTVTYTLENPANTQIKSITATLKKGEEVVKDFVLTEENLKT
                     NHLTALFEKLDYYKEYTLSTDMVYNRGNDDETESISEELIQLNLKKLELKDIQTVSLM
                     KFENGQESQVTHLSDKPTDLSKLYLKVTSSTSKDAVLAVSSIEEEIVENKKIFKIHAD
                     TPELVVRKKDGSLSKGFDYYMERVIPHDGDIYYDFKDLISAMTSNPTGTFILGRDISS
                     RNVKPDGNGKSYIKGEFKGKLLGTNDNVRHSIFDLEYPLFDTIKSGVVKDIDFKHVNM
                     VFPDSNQGDNVATIARVIKDKTKIENVNVEGYLEGRDHVAGLVNNLEGNSEIENISFT
                     GKIKSKGGNSITAGIAGRNILSRVKRAYVNANIEVLGSTNSSMLVAVNGTTLNASGGW
                     GAWGRLTESVAKGTLEIKRSGQAGGVTATVWPYGAIDKVVSYAKVTKGKELFGSDGDL
                     NNNWFMQKINNIFGVQGISSGDSGNDSKFKRISEEEAKQKVASYNITAPNLMSDSSLL
                     VDRLNESWKNTDQFESIQDYQSQNQLIYQNLTKFTPYYNKEFIVHEGNALTPEQEILK
                     TKKIKSIVGLKGTEFVVDGSDIDTIMLHFEDGSQKRYKVTSTGKFSITNLPEYQVEDL
                     NVVYTSEHIVHPLDSSLINNLVEELKKVELYTESTYQVLGIDKDNANKLNRTKRLFLD
                     ESLDAVKTQLPTFVKTMFENEWLHINGESSGAVAALRQKIMDNKTAILLALTYINRYY
                     DVKFSDYNIKKLMLFKPTFHGEKIDLLDRLIRLGSSGENRLKGSENAETFKQLFASET
                     KQKDLVTYLDYNRSLLTNYQTTGEWFKETTKDYIQFEERPSLVEEIKDAKYRVYDNLT
                     APYYQGYILPLLTLKNTHLAILSNYSTMTFVSREKRPNWKNEDFDKWVKYVATAHRNH
                     VDTWYKILPDNIKGKMVKENVTAVWEGLSIPGSEWVDQNAVDRKGRDYAPAREFFNLV
                     GGPMGGWYAYHGYGAHAGGRNRVNYEVFDVLSEYGISVFTHELTHVNDTWIYLGGYGR
                     RENMGPEAYAQGLFQSPVPGQPGWGALGLNMAFERKNDGDLIYNASPTQFENRKELDS
                     YMKNYNDTLMMVDYLEGDAVISKGKEAITKWFKKVEPKVVSQTAQYDTVRQLTAEEKE
                     KLSVSSVDDLVDQGLMSDRAVGNNTYNPADFETSYIAIDYMTGIYGGGKNSVGSPGAL
                     MFKHNTFRMWGYYGFEEGVLGYASNKFKQASRDEGHAGLSDNFIISKISKGEFLTMEA
                     FKKGYFKKVVEELKTKGIRPVTINQKTYSTFEELQEGFKQAVERDLKKNQLDERETRN
                     FKFQVFRQLLQQTDSFKTSIFR"
     gene            30139..31860
                     /gene="pabB"
                     /locus_tag="VW348_000848"
     CDS             30139..31860
                     /gene="pabB"
                     /locus_tag="VW348_000848"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEU9745775.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKNLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            31861..32478
                     /locus_tag="VW348_000849"
     CDS             31861..32478
                     /locus_tag="VW348_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU9745776.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SFMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            32528..33526
                     /locus_tag="VW348_000850"
     CDS             32528..33526
                     /locus_tag="VW348_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU9745777.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DIHEREPGYSAKLDRDHDGVACELKNAPKGAFKAKQSTAIQINTSSATTSGWVKQDGA
                     WYYFDGNGNLVKNAWQGSYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTV
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDD"
     gene            33653..34612
                     /locus_tag="VW348_000851"
     CDS             33653..34612
                     /locus_tag="VW348_000851"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEU9745778.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            34709..35548
                     /locus_tag="VW348_000852"
     CDS             34709..35548
                     /locus_tag="VW348_000852"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEU9745779.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRIDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(35596..35766)
                     /locus_tag="VW348_000853"
     CDS             complement(35596..35766)
                     /locus_tag="VW348_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEU9745780.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            35887..36771
                     /gene="miaA"
                     /locus_tag="VW348_000854"
     CDS             35887..36771
                     /gene="miaA"
                     /locus_tag="VW348_000854"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEU9745781.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEGIHNRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVDQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQETLYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEASESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            36764..38002
                     /gene="hflX"
                     /locus_tag="VW348_000855"
     CDS             36764..38002
                     /gene="hflX"
                     /locus_tag="VW348_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEU9745782.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            37995..38618
                     /locus_tag="VW348_000856"
     CDS             37995..38618
                     /locus_tag="VW348_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEU9745783.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            38633..39562
                     /locus_tag="VW348_000857"
     CDS             38633..39562
                     /locus_tag="VW348_000857"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEU9745784.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            39583..40338
                     /locus_tag="VW348_000858"
     CDS             39583..40338
                     /locus_tag="VW348_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU9745785.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEPDAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(40392..41300)
                     /locus_tag="VW348_000859"
     CDS             complement(40392..41300)
                     /locus_tag="VW348_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU9745786.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            41364..41633
                     /locus_tag="VW348_000860"
     CDS             41364..41633
                     /locus_tag="VW348_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEU9745787.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            41633..42013
                     /locus_tag="VW348_000861"
     CDS             41633..42013
                     /locus_tag="VW348_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU9745788.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            42131..42328
                     /locus_tag="VW348_000862"
     CDS             42131..42328
                     /locus_tag="VW348_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745789.1"
                     /translation="MGILSIILGLLFPIVGLILGIIGLVLAISYQKESQLDYKIEKIL
                     NILGIVISVVNWIVAIALIFR"
     gene            complement(42368..43093)
                     /locus_tag="VW348_000863"
     CDS             complement(42368..43093)
                     /locus_tag="VW348_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HEU9745790.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSISQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            43255..45096
                     /gene="typA"
                     /locus_tag="VW348_000864"
     CDS             43255..45096
                     /gene="typA"
                     /locus_tag="VW348_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEU9745791.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPVEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            45116..45370
                     /locus_tag="VW348_000865"
     CDS             45116..45370
                     /locus_tag="VW348_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEU9745792.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
BASE COUNT        13940 a         8393 c        10120 g        13086 t
ORIGIN      
        1 tttttgatat tcagagcgat gaaaatccgt tttttgaagt tttcaaagtt tcgaaaacca
       61 aaggcattgc gcttgataag tttgatgaga ttattggtcg cttccagttt ggcattagaa
      121 tagtgtagtt gaagggcatt gacaatcttc tctttatctt tgaggaaggt tttagaggat
      181 gaacctgatt cagattgtcc tcaatgagtc cgaaaaattt gtcaggctcc ttattctgaa
      241 agtgaaaaag caagagttga tagagattat agtggtgttt caagtcttct gaatagctca
      301 aaagtttatc tatagtagat tgaaactaga atagtacacc tctgcttcta aaacattgtt
      361 agaaatcgat ttgactgtcc tgaatgattt gtcctgttat tatttcattt tactataaat
      421 ccacgtttac gaatctcttt ccacacttgt tcaatggggt tcatctctgg tgtgtatgga
      481 ggaataaatg caaaaccaat attagtcgga atctttaagg tacttgattt atgccatata
      541 gcattgtcca taacgagtaa aagataatca tctggataag cttgtgaaag ctcctattcc
      601 taaagcccct ttataacctc ttgcgagaga gactattgac tcagccctta cttcatgcgg
      661 atgaaacttc ttatcgggtt ctagagagtc atagccatct gacctactat tggacctttt
      721 tgtctgggaa agttgagaat caagcaatca cgctgtacca tcatgatcag agtcggagtg
      781 gttcggtagt acaagaattc ctaggagatt attctggcta tgttcattgt gatatgttgc
      841 ggcagtaact taggacttta gtcctctagt tctgcctatg cgatagcagt ccaaggttta
      901 ggagcaaggc gacgctaagc ttggtaaact gcgaactgct agaagcttat cgtcaactgg
      961 aagaagctga acttgttgga tgttgggcgc atgtgagaag gaaatttttt gaagcgaccc
     1021 ccaagcaagc agataaatca tccttaggag ctaaaggttt agcttattgt gatcagttat
     1081 tttccttgga aagagactgg gaggctttgc cagctgatga acgactacag aaacgtcaag
     1141 aacatctcca gcccctaatg gaagacttct ttgcttggtg tcgccgtcag tcagttttag
     1201 caggttcaaa actaggaagg gcaattgaat acagcctcaa gtatgaagaa acctttaaga
     1261 ctattttgaa agacggacat ctggtccttt ccaataatct agctgaacgc gccattaaat
     1321 cattggttat gggacggagt aaaagagtcc agtggactct tttagcctga gctcagttta
     1381 aaaaagcgag ggtggttatt ttctcaaagt tttgaaggag ctaaagcaag agctattatt
     1441 atgagcttgt tggaaacagc taaacgtcat caattatagt gcgttgaatc tataacagta
     1501 cgcatcgact gctaaaacat ttctataaat caattttcct ttcctaatcg atttgttcat
     1561 atcttatttc aatccattat aaatagcgag aaatatctat cctatcttct agaatgtctt
     1621 ccaaacgagg aaactctcgt aaacaaagag gttttagagg cctatttacc atggactaaa
     1681 gttgtacaag aaaagtgcaa ataagaaatc tccagattag gaactatccg tgagttcact
     1741 aatctggaga tttttcaata gacttcgtta ttgggcggtt acgatatgat cactgacttc
     1801 gtcagtctta tctacaacct caaaactgtg ttttgagcaa cctgcggcta gcttcctagt
     1861 ttgctctttg attttcattg agtattagaa cagaaaaaat acttggagta tttgtttgtg
     1921 tgtttatttt tatataacaa actataaaca aaacaaaaat ataaaaaaag agacaaaaaa
     1981 agaacagaaa gcaattgaca acggtttcat atagtgttat acttatggca taaagttaat
     2041 ggaaagaagg gaaaaactta tggtattaga ttatttcttt gacaaaaacc ttgtgttttg
     2101 cttagaagcg gataatcaag aacaactctt tgatcaggtt gcaactttat tggaagaacg
     2161 agaaattgtc actccaactt atcgtgaagc cttgatcacg cgtgaaaagt catttccaac
     2221 tggtttagat atggaatttc taggaaagga cttgccaaat gtagcgattc ctcatacaga
     2281 tattgttcat aatctagctg agaaagtggt ggttgttcga ttagaaaaac cagtaacttt
     2341 tcacaatatg atagctcctg ataaggaagt agaagtatcc ctactcttct ttattattaa
     2401 caattcaagt tcaagtcaaa caaatattct ggctcagttg atggactttt tcacaggaaa
     2461 tggacatctt gaagacctat caaaaatttc cgaaccagaa aaactttatg cttacattgc
     2521 tgaagcaacc gcttaatctt gtctattaaa aaataaaatc ggaggaaatc caaatgatta
     2581 aaattcttgc tgcctgcggt gcaggtgtta actcaagtca ccaaattaaa agtgctctag
     2641 aagaagaact ttcaaaccgt ggttatgatg ttcactgtga tgcagtcatg gtgaaagatg
     2701 taaacgaaga ccttatgaaa ggttacgata tctttacacc aatcgctgca acagaccttg
     2761 gttttgaacc aggtatccca gttatcgaag ctgggccaat cttattccgt atcccagcaa
     2821 tgagcgctcc agtatttgac aatattgaag cagctattaa agaacacgga ttaagctaat
     2881 tctaatttgt taacattcat ataacataaa aaagggagga actgttatgg atgcaatctt
     2941 tgacctaatc ggaaaggttt tcaatcccat tttagaaatg ggtggacctg tcatcatgtt
     3001 aatcattttg acagtattgg ctttactttt tggagtgaaa ttctccaaag cgcttgaagg
     3061 tggtatcaaa cttgccatcg ctcttacagg tatcggtgct atcatcggta tgctaaatgg
     3121 tgctttctca gcatcacttg caaaattcgt tgaaaacact ggtatccaat tgagtattac
     3181 cgacgttggt tgggcaccac tcgcaacaat cacttggggt tctgcttgga cactatactt
     3241 cttgctcatc atgttgattg tcaacatagt gatgctagct atgaagaaaa cagatacact
     3301 tgacgttgat atctttgata tctggcactt gtctatcaca ggtctcttga ttaaatggta
     3361 tgctgataac aatggtgtga gtcaaggggt ttcactcttt attgctacag cagctatcgt
     3421 ccttgtcggt gtgttgaaaa ttatcaactc tgacttgatg aaacctacat ttgatgacct
     3481 tcttaacgcc ccaagttcat caccaatgac atcaactcac atgaactaca tgatgaaccc
     3541 agttatcatg gttttggata agatttttga aaaattcttc ccaggccttg ataaatatga
     3601 ctttgatgct gctaaattga acaagaaaat cggtttctgg ggatctaaat tcttcatcgg
     3661 tttcatcctt ggtatcgtta tcggtattat gggaactcca catccaattg caggtgttgc
     3721 agatgcagat aaatggcgtc ttgttatcaa aggatggttg tctcttggtt tgactgccgg
     3781 tgtatctttg gaactcttct cacttatcgg ttcatggttc atcgcagccg tagaaccact
     3841 atcacaaggt attacaaacg ttgctactaa acgtcttcaa ggacgtaaat tcaatatcgg
     3901 tcttgactgg ccattcatcg ctggtcgtgc tgaaatctgg gcttgtgcca acgtacttgc
     3961 accaatcatg ttgattgaag cagtgcttct ttcaaaagtt ggaaatggta tcttgccact
     4021 tgcaggtatc atcgctatgg gtgttactcc agctctcttg gttgtaactc gtggtaaatt
     4081 gctccgtatg attatcttcg gaacactctt gttgccactc ttccttcttt caggtacact
     4141 tattgcacca tttgcaacag aacttgctaa aggtgtaggt gccttcccag aaggtgtgag
     4201 ccaaactcaa ttgattactc actctactct tgaaggacca atcgaaaaac ttcttggttg
     4261 gacaattggt aacactacaa ctggtgatat caaagcaatc cttggtgcag tagtcttcct
     4321 tgtattctat atcggtatct ttgcttggta cagaaaacaa atgatcaaac gtaacgaaga
     4381 gtacgcagca aaagcaaaat aatgcgctcc tataaaatat aaactcaatg aaaatcaaag
     4441 agcaaactag gaaactagcc acaggttgct caaaacacag ttttgaggtt gtagataaga
     4501 ctgacgaagt cagctcaaaa catggttttg aggttgtaga tgaaactgac gaagtcagta
     4561 atcatatcta cggcaaggcg acactgacga agtttgaatt ggattttcgc agagtgtaaa
     4621 ttgttgaaac taggttgtca taccatgtat accacttggg ctttggcagt agctaactgc
     4681 actaaatata atataaggag ggttttatgg ggaaaggcca ttggaatcgg aaaagagttt
     4741 atagcattcg taagtttgct gtgggagctt gctcagtaat gattgggact tgtgcagttc
     4801 tattaggagg aaatatagct ggagaatctg tagtttatgc ggatgaaaca cttattactc
     4861 atactgctga gaaacctaaa gaggaaaaaa tgatagtaga agaaaaggct gataaagctt
     4921 tggaaactaa aaatgtagtt gaaaggacag aacaaagtga acctagttca actgaggcta
     4981 ttgcatctga gaagaaagaa gatgaagccg taactccaaa agaggaaaaa gtgtctgcta
     5041 aaccggaaga aaaagctcca aggatagaat cacaagcttc aagtcaagaa aaaccgctca
     5101 aggaagatgc taaagctgta acaaatgaag aagtgaatca aatgattgaa aacaggaaag
     5161 tggattttaa tcaaaattgg tactttaaac tcaatgcaaa ttctaaggaa gccattaaac
     5221 ctgatgcaga cgtatctacg tggaaaaaat tagatttacc gtatgactgg agtatcttta
     5281 acgatttcga tcatgaatct cctgcacaaa atgaaggtgg acagctcaac ggtggggaag
     5341 cttggtatcg caagactttc aaactagatg aaaaagacct caagaaaaat gttcgcctta
     5401 cttttgatgg cgtctacatg gattctcaag tttatgtcaa tggtcagtta gtggggcatt
     5461 atccaaatgg ttataaccag ttctcatacg atatcaccaa atacctttac aaagatggtc
     5521 gtgagaatgt gattgctgtc catgcagtca acaaacagcc aagtagccgt tggtattcag
     5581 gaagtggtat ctatcgtgat gtgactttac aagtgacaga taaggtgcat gttgagaaaa
     5641 atgggacaac tattttaaca ccaaaacttg aagaacaaca acatggcaag gttgaaactc
     5701 atgtgaccag caaaatcgtc aatacggacg acaaagacca tgaacttgta gccgaatatc
     5761 aaatcgttga acgaggtggt catgctgtaa caggcttagt tcgtacagcg agtcgtacct
     5821 taaaagcaca tgaatcaaca agcctagatg cgattttaga agttgaaaga ccaaaactct
     5881 ggaccgtttt aaatgacaaa cctgccttgt acgaattgat tacgcgtgtt taccgtgacg
     5941 gtcaattggt tgatgctaag aaggatttgt ttggttaccg ttactatcac tggactccaa
     6001 atgaaggttt ctctttgaat ggtgaacgta ttaaattcca tggagtatcc ttgcaccacg
     6061 accatggggc gcttggagca gaagaaaact ataaagcaga atatcgccgt ctcaaacaaa
     6121 tgaaggagat gggagttaac tccatccgta caacccacaa ccctgctagt gagcaaacct
     6181 tgcaaatcgc agcagaacta ggtttactcg ttcaggaaga ggcctttgat acttggtatg
     6241 gtggcaagaa accttatgac tatggacgtt tctttgaaaa agatgccact cacccagaag
     6301 ctcgaaaagg tgaaaaatgg tctgattttg acctacgtac catggtcgaa agaggcaaaa
     6361 acaaccctgc tatcttcatg tggtcaattg gtaatgaaat aggtgaagct aatggtgatg
     6421 cccactcttt agcaactgtt aaacgtttgg tcaaggttat caaggatgtt gataagactc
     6481 gctatgttac catgggagca gataaattcc gtttcggtaa tggtagcgga gggcatgaga
     6541 aaattgctga tgaactcgat gctgttggat ttaactattc tgaagataat tacaaagccc
     6601 ttagagctaa gcatccaaaa tggttgattt acggttcaga aacatcatca gcaacccgta
     6661 cacgaggaag ttactatcgc cctgaacgtg aattgaaaca tagcaatgga cctgagcgta
     6721 attatgaaca gtcagattat ggaaatgatc gtgtgggttg ggggaaaaca gcaaccgctt
     6781 catggacttt tgaccgtgac aacgctggct atgctggaca gtttatctgg acaggtacgg
     6841 actatattgg tgaacctaca ccatggcaca accaaaatca aactcccgtt aagagctctt
     6901 actttggtat cgtagataca gccggcattc caaaacatga cttctatctc taccaaagcc
     6961 aatgggtttc tgttaagaag aaaccgatgg tacaccttct tcctcactgg aactgggaaa
     7021 acaaagaatt agcatccaaa gtagctgact cagaaggtaa gattccagtt cgtgcttatt
     7081 cgaatgcttc tagtgtagaa ttgttcttga atggaaaatc tcttggtctt aagactttca
     7141 ataaaaaaca aaccagcgat gggcggactt accaagaagg tgcaaatgct aatgaacttt
     7201 atcttgaatg gaaagttgcc tatcaaccag gtaccttgga agcaattgct cgtgatgaat
     7261 ctggcaagga aattgctcga gataagatta cgactgctgg taagccagcg gcagttcgtc
     7321 ttattaagga agatcatgcg attgcagcag atggaaaaga cttgacttac atctactatg
     7381 aaattgttga cagccagggg aatgtggttc caactgctaa taatctggtt cgcttccaat
     7441 tgcatggtca aggtcaactg gtcggtgtag ataacggaga acaagccagc cgtgaacgct
     7501 ataaggcgca agcagatggt tcttggattc gtaaagcatt taatggtaaa ggtgttgcca
     7561 ttgtcaaatc aactgaacaa gcagggaaat tcacccttac tgcccactct gatctcttga
     7621 aatcgaacca agtcactgtc tttactggta agaaagaagg acaagagaag actgttttgg
     7681 ggacagaagt gccaaaagta cagaccatta ttggagaggc acctgaaatg cctaccactg
     7741 ttccgtttgt atacagtgat ggtagccgtg cagaacgtcc tgtaacctgg tctcaagtcg
     7801 atgttagtca agcaggagtt gtgactgtta aaggtacagc aaatggacgt gaggtagagg
     7861 ctcatgtcaa ggttctagca attgcgaaag aattaccaac agttaaacgt attgctccaa
     7921 atactgactt gaattctgta gacaaatctg tttcttatgt tttgactgat ggaagtgtac
     7981 aagagtacga agtagatagc tgggagatta cggaagtaga taaagccaaa ctttcagtag
     8041 ctggatcacg tattcaaatg actggtcagt tagctggaga aactattcat gcaacccttg
     8101 tggtagaaga aggaaatgct gcagcacctg tagtgccaac tgttactgtt ggaggtgaag
     8161 cagtaacagg tcttactagt cgacaaccaa tgcaatatcg tactctatct tatggtgccc
     8221 aattgccaga agtcacagca agtgctgaaa atgctgatgt gacagttctt caagcaagcg
     8281 cagcaaacgg catgcgtgcg agcatcttta ttcagcctaa agatggtggc cctcttcaaa
     8341 cctatgcaat tcaattcctt gaagaagcgc caaaaattgc tcacttgagc ttgcaagtgg
     8401 aaaaagctga cagtctcaaa gaagaccaaa ctgtcaaatt gtcggttcga gctcactatc
     8461 aagatggaac gcaagctgta ttaccagctg ataaagtaac cttctctaca agtggtgaag
     8521 gggaagtcgc aattcgtaaa ggaatgcttg agttgcataa gccaggagca gtcactctga
     8581 acgctgaata tgagggagct aaagaccaag ttgaactcac tatccaagcc aatactgaga
     8641 agaagattgc gcaatccatc cgtcctgtaa atgtagtgac agatttgcat caggaaccaa
     8701 gtcttccagc aacagtaaca gttgagtatg acaaaggttt ccctaaaact cataaagtca
     8761 cttggcaagc tattccgaaa gaaaaactag actcctatca aacatttgaa gtactaggta
     8821 aagttgaagg aattgacctt gaagcgcgtg caaaagtctc tgtagaaggt atcgtttcag
     8881 ttgaagaagt cagtgtgaca actccaatcg cagaagcacc acaattacca gaaagtgttc
     8941 ggacatatga ttcaaatggt cacgtttcat cagctaaggt tgcatgggat gcgattcgtc
     9001 cagagcaata cgctaaggaa ggtgtcttta cagttaatgg tcgcttagaa ggtacgcaat
     9061 taacaactaa acttcatgtt cgcgtatctg ctcaaactga gcaaggtgca aacatttctg
     9121 accaatggac cggttcagaa ttgccacttg cctttgcttc agactcaaat ccaagcgacc
     9181 cagtttcaaa tgttaatgac aagctcattt cctacaataa ccaaccagcc aatcgttgga
     9241 caaactggaa tcgtactaat ccagaagctt cagtcggtgt tctgtttgga gattcaggta
     9301 tcttgagcaa acgctccgtt gataatctaa gtgtcggatt ccatgaagac catggagttg
     9361 gtgtaccgaa gtcttatgtg attgagtatt atgttggtaa gactgtccca acagctccta
     9421 aaaaccctag ttttgttggt aatgaggacc atgtctttaa tgattctgcc aactggaaac
     9481 cagttactaa tctaaaagcc cctgctcaac tcaaggctgg agaaatgaac cactttagct
     9541 ttgataaagt tgaaacctat gctgttcgta ttcgcatggt taaagcagat aacaagcgtg
     9601 gaacgtctat cacagaggta caaatctttg cgaaacaagt tgcggcagcc aagcaaggac
     9661 aaacaagaat ccaagttgac ggcaaagact tagcaaactt caaccctgat ttgacagact
     9721 actaccttga gtctgtagat ggaaaagttc cggcagtcac agcaagtgtt agcaacaatg
     9781 gtctcgctac cgtcgttcca agcgttcgtg aaggtgagcc agttcgtgtc atcgcgaaag
     9841 ctgaaaatgg cgacatctta ggagaatacc gtctgcactt cactaaggat aagagcttac
     9901 tttctcataa accagttgct gcggttaaac aagctcgctt gctacaagta ggtcaagcac
     9961 ttgaattgcc gactaaggtt ccagtttact tcacaggtaa agacggctac gaaacaaaag
    10021 acctgacagt tgaatgggaa gaagttccag cggaaaatct gacaaaagca ggtcaattta
    10081 ctgttcgagg ccgtgtcctt ggtagtaacc ttgttgctga ggtcactgta cgagtgacag
    10141 acaaacttgg tgagactctt tcagataacc ctaactatga tgaaaacagt aaccaggcct
    10201 ttgcttcagc aaccaatgat attgacaaaa actctcatga ccgcgttgac tatctcaatg
    10261 acggagatca ttcagaaaat cgtcgttgga caaactggtc accaacacca tcttctaatc
    10321 cagaagtatc agcgggtgtg attttccgtg aaaatggtaa gattgtagaa cggactgttg
    10381 cacaaggaaa agttcagttc tttgcagata gtggtacgga tgcaccatct aaactcgttt
    10441 tagaacgcta tgtcggtcca gagtttgaag tgccaaccta ctattcaaac taccaagcct
    10501 acgacgcaga ccatccattc aacaatccag aaaattggga agctgttcct tatcgtgcgg
    10561 ataaagacat tgcagctggt gatgaaatca acgtaacatt taaagctatc aaagccaaag
    10621 ctatgagatg gcgtatggag cgtaaagcag ataagagcgg tgttgcgatg attgagatga
    10681 ccttccttgc accaagtgaa ttgcctcaag aaagcactca atcaaagatt cttgtagatg
    10741 gaaaagaact tgctgatttc gctgaaaatc gtcaagacta tcaaattacc tataaaggtc
    10801 aacggccaaa agtctcagtt gaagaaaaca atcaagtagc ttcaactgtg gtagatagtg
    10861 gagaagatag ctttccagta cttgttcgcc tcgtttcaga aagtggaaaa caagtcaagg
    10921 aataccgtat ccacttgact aaggaaaaac cagtttctga gaagacagtt gctgctgtac
    10981 aagaagatct tccaaaaatc gaatttgttg aaaaagattt ggcatacaag acagttgaga
    11041 aaaaagattc aacactgtat ctaggtgaaa ctcgtgtaga acaagaagga aaagttggaa
    11101 aagaacgtat ctttacagcg attaatcctg atggaagtaa ggaagaaaaa ctccgtgaag
    11161 tggtagaagt tccgacagac cgcatcgtct tggttggaac caaaccagta gctcaagaag
    11221 ctaaaaaacc acaagtgtca gaaaaagcag atacaaaacc aattgattca agtgaagcta
    11281 gtcaaactaa taaagcccag ttaccaagta caggtagtgc ggcaagccaa gcagcagtag
    11341 cagcaggttt aactcttcta ggtttgagtg caggattagt agttactaaa ggtaaaaaag
    11401 aagactagaa attttgatac cttctttatc attaaagacc aaagaaaaac tcttgtccta
    11461 aatagaagat aaagagcctg agacaaaata gttctcaacc acaaaaaagc tagatatttc
    11521 caattgtgga actctagctt tttaattttg agtcattctc ttattgtata gtagattgaa
    11581 actagaatag tacactttta cttctaaaac attgttagaa atcgatttga ttgtccttat
    11641 cgatttgtcc tgttcttatt tcattttact atattttagg aggttattgg ccataagtac
    11701 caatcccatg tcaattctca cttgacgctt ccctctcaga ttacatctct tgtaacccaa
    11761 agaagccttt atctgcccaa agacaggttc cacatcaatc ttgcgttgag cgaaaatctg
    11821 tctaccttgg ggagataaaa gcgcctgaca ttctttagct ttcaagtttt gatagcgttc
    11881 gttcatatac agtccctttt gaggggctga ttcaggttcg tcggcgtagt aaaccttgat
    11941 ttcttgttga aagtctgtct gtgttttctg atatttggta tggtgaaaac gataatacca
    12001 gccatcagga tgtgtgtagc tatcctcctt gtcattatag tgccaattcg ctaagttttt
    12061 agctgactct ttataccctc tcttttgttt cttatcaaac atggcatatt taatcagaag
    12121 gggagtgatt tcttcttgaa aatagacctg tatctgttct tgaagtttgg cggagaattt
    12181 ctctgtcgtt ttcttccaca caaaactata cttgttggca ttggcttcaa tcttagttct
    12241 gtcaataaac aaacaatcta aggtcactaa ctcttccatt tttcaatttt tcgaccagag
    12301 aaaatccctt gtgaataggc aaatagaaga gtagatacaa gcattttagg gtgataagac
    12361 gggcgatcaa aggcatgata ggaggtgtag aagtgacgtt cctccaaggt attcaccact
    12421 ttttcaatag taaaaacgag atgatcttgt ggtaagaagg aactgatttc tagtggtaaa
    12481 gttgtttgat ttgtgttata gtgaatatgc atgggatagc ctttctaaat ggtttattgg
    12541 gcaattctat tttaccaaga ctatcgtaac catgcaaaaa agcaacggca aatccgttgc
    12601 ctttttggat ataagagact attgtcccag actcttttct ttgtataaaa ttgtatagtg
    12661 ttattgtcta tactattttg tagagaaagc aaaaatccct agaaaatgct tagggattcg
    12721 actatttcat taagaacaat tcaacaatca tttctatata catgataagg gttaataaga
    12781 atcctgcacg ccagaagaat ttgataaatt taggatagta aaagctgcgt tttttcaaaa
    12841 ggaagaaaaa gacgagaata atggctagga tcgagagggc tagccccagt ctagggagga
    12901 aattatgggt aaaggtttta gctgtaatca agtaatactc aaataccaag actggaaaag
    12961 ccaaatccgc aaagtttcgt cctagttttt ttaatctaaa aagtttggtt aggataatgc
    13021 agacgactaa ggtcagtatc aataataaaa tagatgctaa tttcattaaa atcataccca
    13081 tattgtatca taaaaaaagg ctaatggaaa cgagaaacag aggaatttat aggaaagtca
    13141 ggcttttgag attgtgggtg atttttgtta taatgaaagt catgaaatct tataatacct
    13201 tgaatgatta ttatcgaaaa ctctttggag aaaagacttt taaagtccct attgatgcgg
    13261 gatttgactg tcccaatcgt gatggaactg tggctcatgg aggctgtact ttttgtacgg
    13321 tttcaggttc tggagatgct attgtagccc cagatgcgcc tatccgtgag caattttata
    13381 aggaaattga ctttatgcac cgtaagtggc cggatgttca gaagtatctg gtttattttc
    13441 aaaattttac caacacccat gaaaaggtgg aagttgttcg agagcgttat gaacaggcta
    13501 tcaatgagcc aggtgtggta ggtatcaata ttggaacgcg cccagactgt ttaccagacg
    13561 aaaccatcga atatttggct gagttatcgg agtgcatgca tgtgacggtt gaattgggct
    13621 tgcaaactac ttatgaagca acctctgacc tgattaaccg tgcgcattct tatgaattgt
    13681 aggtggaaac ggtcaagcgt ttgagaaagt atccaaaaat tgagattgtt tcccatttga
    13741 tcaatggttt gcctggtgaa acccatgaga tgatggttga aaatgtccgc cgttgtgtca
    13801 cgaataacga tattcaaggg attaaactgc atttgctcca tcttatgaca aatactcgta
    13861 tgcaacgaga ttaccatgag ggacgtttac aattgatgag tcaggacgaa tatgtcaggg
    13921 tcatctgtga ccaactggaa atcattccca aacatatcgt catccatcga attacaggag
    13981 atgcgcctag ggatatgctg cttgggctta tgtggagcct caataaatgg gaagctctca
    14041 acagcattga gatggagatg cgacgtcgtg gaagtgttca aggatgcaag gctgtaaaac
    14101 aggagtttga aaatgaaaag accacttgag atggcacatg attttttggc tgaggtcgtg
    14161 acaaaagagg atgtcgtagt ggatgcgact atgggaaatg gtcatgacac gcttttttta
    14221 gccaagctag ccaagcaagt ctatgccttt gatattcaga agcaagcctt ggaaaagacc
    14281 caagagcgtt tgcatcaggc tggcttgaca aatgcccagt taatcttgca aggccatgag
    14341 acactggacc agtttgtgac aaaagctaag gcagggattt ttaatttggg ctatttgccg
    14401 tcagctgata agtctgtcat cacccgaccg cagacaacga ttgaggcatt agaaaagcta
    14461 tgtggcttac ttgtcaaagg tggacgaatt gctattatga tttactatgg tcatgaagga
    14521 ggcgacctcg agagagatgc tgtcttggat tttgtgatcc agttgaacca acaagagtac
    14581 acagctgcca tttaccgaac tttaaaccaa gtcaacaacc cgccgttttt agtgatgatt
    14641 gaaaaattag agagatacag acatggataa acaataccta cacgaaaagc tggatgccat
    14701 gcgccagaat tttgttgaat caacccacca cgaacgagcg gtgggcgtgc tagaccaagc
    14761 gcatatgagc aaaaaaatgc ttaaaatcaa gaaaaaatta gttgctcttg aaatggaacg
    14821 gtgccagaga aaaattgagc acaaagactg ttccaagatt gaccaaaaaa tcaaagagca
    14881 gaaggagata tttgaatcct gttgtaaaaa agattaagga ggacgtgcgt ggaattactg
    14941 atttacctca tcctattttt actggttttg attgtctcaa gtacaaccaa taagctcctg
    15001 ccctttttgc ctctcccttt ggtgcagatt cttttgggaa ttgtgattgg tctcttttta
    15061 cccaatactg actttcacct taatacggag ttgtttttgg cactggttat cggacccttg
    15121 cttttccgag aggctgaaga agcagatgtt acggctattt taaaacactg gcgaatcatt
    15181 gtttatctca tatttccagt gatttttatc tcgaccctga gtttgggtgg cttggcccat
    15241 cttctttggt tcagccttcc cttggcagct tgcttggctg ttggtgcagc ccttggtcct
    15301 acggacttgg tggcctttgc ctctctttcg gagcgtttta gctttcctaa gcgcgtgtcc
    15361 aatattctta agggcgaagg actcttgaat gatgcttctg gtttggtggc ttttcaggta
    15421 gctttgacag cttggacaac tggagctttt tctctggggc aagctagcag ttcgctcatc
    15481 ttttcaatcc taggcggttt tttaattgga tttttaacag ccatgaccaa ccgcttcctc
    15541 cataccttct tgctaagtgt gcgcgcaacg gatattgcca gtgaactttt attagaattg
    15601 agtttgcctc tagtgacctt ctttctggca gaagaagtcc atgtttcagg gattattgcc
    15661 gtcgtagttg ctggaatttt aaaggcaagt cgcttcaaga aaatcacgct cctcgaagcc
    15721 caagtggata cggtgaccga gacggtctgg catacagtga cctttatgct caacggttct
    15781 gtctttgtga ttttagggat ggagttggaa atgatagcag aacctatctt gaccaatcca
    15841 atctataatc ctctactttt attgctatct ctcatcgccc ttacctttgt cctctttgtc
    15901 attcgtttta ttatgatcta tggctattat gcctatagaa cccgacgcct caagaaaaag
    15961 ctaaataagt atatgaagga catgtttctc ttgacctttt caggtgttaa gggaacggtg
    16021 tcgattgcta cgattctctt gataccaagt aatctagaac aggagtatcc tctcttgctt
    16081 ttccttgttg caggtgtgac gcttgtcagc tttttaacag gtctcttggt cttgcctcat
    16141 ctttctgatg aagaggaaga aagcaaggat tatctcatgc atatcgccat tttgaatgaa
    16201 gtaacgctag agttggaaaa agagttggaa gacaccagaa ataaacttcc cctctatgcg
    16261 gctattgaca attatcatgg acgtattgaa aatctcattt taagccaaga aaaccaggat
    16321 gatcaagaag attgggctgc tttgaaactc ttgattctta gtattgaaag tgatggtttg
    16381 gagcaggcct atgaagaggg gaacattagc aatcgtgctt accgagttta ccaacgttat
    16441 ctgaaaaata tagaacaagg aatcaatcgt aaacttgcct caagactgac ctattatttc
    16501 cttgtttctt tgcggatttt acgttttctc cttcatgaag tttttactct cggaaagacc
    16561 ttccgtagct ggaagaacaa ggagcaaagc cgtctccgtg ctcttgatta tgaccaaatt
    16621 gcagagctct atcttgccaa tacagagatg attattgaaa gtttggaaaa cctgaaggga
    16681 gtctacagac gctctttgat tagttttatg caggagtctc gtcttcgaga aacagctatt
    16741 atcagcagtg gtgcctttgt cgaacgggtt atcaatcgtg tcaaacccaa caatatcgat
    16801 gaaatgctga gaggctatta tctggagcgc aagttgattt tcgaatacga agaaaaacga
    16861 ttgattacga ctaagtatgc caagaaatta cgacaaaatg taaataactt agagaactat
    16921 tccttgaagg aagctgccaa taccctaccg tatgatatgg tggaattggt aagaagaaat
    16981 tagttaatac tcttcgaaaa tctcttcaaa ccacgtcagc gtcgccttac cgtatgtatg
    17041 tgactgactt cgtcagtctt atctacaacc tcaaaacagt gttttgagca gcttgcggct
    17101 agctttctag tttgctcttt gattttcatt gagtataaga ttataaatga aggagtatga
    17161 catgaaaaag tggtggaaag agctgataga caaaccttta ttaaaagctt ttttgcatta
    17221 ttatcaagca tcagatagtg agttgaccag tgtcgcagta gcctactatt ggttgatttc
    17281 gattttcccc ctgcttttgg tggtggtcaa tatcctcccc tattttcaga ttcctgtggg
    17341 agaatttttg ggctttatga aagacgtcct gcccccaagc ctctatgaag gtgtggaaaa
    17401 aatagccaga gaagtcttga cgcaaccttc aacaggttta ttgagttttt ctgttttatc
    17461 ggcgttatgg agtttttcaa aatctatgaa tttcttgcaa aaagctttta acaaggctta
    17521 tggcgtcgaa aagagtcgtg gacttatttc ccatcagatg ctaagtctcc tagtcagttt
    17581 tggcttgcag ctcctctttg cgtttgcctt gtttttgatc ttatttggtc agatgatttt
    17641 ggctttactt gctcattatt ggacaaaaga tggcattatc tatcaggctt tacaagggtt
    17701 ggcaggtcct ctgatttacg ccctcctctt tgctatcttg gtcatgcttt attattttct
    17761 tcccaatcta tctaacagga aaattagcta taccctacca ggcagtgcct ttgttctctt
    17821 agtgatttta ggtttactaa ctctgttctc tagttatctc aattactatg tccatcattt
    17881 ggtggatgtc cgaattttag gttccgttct tcttgttgtt atgatgtttt ggtttatctt
    17941 gattgctaaa attgttatcc taggcgcggt gatcaatgcc agtatgcaga gtttgaaaga
    18001 tccggtcttt aaaaaagact aactatttat ccattacaaa agcgcatagt atcaagattc
    18061 tataaagcct tgatactatg cgcttttgtg ctttgacagt tttttgtata gtttttgtcc
    18121 aagatttcta aatcatctga ttaaattcct attttcccct atcattgtcc ctgttttttc
    18181 gaaaatggaa ggagtataat aaatctatca ataaaatgat aggaggaact ttatgggtca
    18241 tattttcttt tttctaagtg tctttttggc agggattcta tccttctttt ctccttgtat
    18301 cttacctttg ttaccggtct atacaggagt gttactagat gataaggatg gtgctcaggc
    18361 ttctagcggc aaattttcaa tctcagttac tagtttatta cgaactctgg cctttatagc
    18421 aggaatttcc tttatattta ttttgttggg ctatggagct ggttttttag gcgatttgct
    18481 ttatgcttct tggttccaat atcttactgg ggcaattatt atccttcttg gtttgcacca
    18541 aatggagatt ctacacttta aggggcttta taaggaaaag aggctacaac tgcaaggaca
    18601 ggggcaaaat ggtaagggct atagtcaggc atttttattg ggcttgacct ttagttttgc
    18661 ttggacgcct tgcgtggggc cggttctggg gtctgttttg gccttggcgg cttcaggtgg
    18721 ttcaggagct tggcagggag ctggtctcat gttggtgtat acgctgggct tggcgctacc
    18781 attcttgctt ctagctctga cctctagtta tgttttgaaa catttccgaa aacttcatcc
    18841 ctatctcgga atcctcaaaa aagtgggtgg ttttctcatt attgtgatgg gattcttggt
    18901 tctgtttgga aatgcttcaa ttttaagtca attatttgaa taaaatggaa aggaatatca
    18961 atatgaaaaa atggcaaaca tgtgttcttg gagcaggttc gctcctttgt ttgacggctt
    19021 gttcaggcaa gtccgtgact agtgaacacc aaacgaaaga tgaaatgaag acggagcaga
    19081 cagctagtaa aacaagcgca gctaaaggga aagaggtggc tgattttgaa ttgatgggag
    19141 tagatggcaa gacctaccgt ttatctgatt acaagggcaa gaaagtctat ctcaaattct
    19201 gggcttcttg gtgttctatc tgtctggcta gtcttccaga tacggatgaa attgctaaag
    19261 aagctggtga tgactatgtg gtcttgacag tagtgtcacc aggacataag ggagagcaat
    19321 ctgaagcgga ctttaagaat tggtataagg gattggatta taaaaatctc ccagttctag
    19381 ttgacccatc aggcaaactt ttggaaactt atggtgtccg ttcttaccca acccaagcct
    19441 ttatagacaa agaaggcaag ctggtcaaaa cacatccagg attcatggaa aaagatgcaa
    19501 ttttgcaaac tttgaaggaa ttagcctagg aggcgtctta tgaatgataa gttaaaaatc
    19561 ttcttgttgc taggagtatt ttttctagcc ataaccggtt tctatgttct attgatacga
    19621 aatgcagggc agacagatgc ctcgcaaatt gaaaaggcgg cagttagcca aggaggaaaa
    19681 gcagtgaaaa aaacagaaat tagtaaagac gcagacttgc acgaaattta tctagctgga
    19741 ggttgtttct ggggagtgga ggaatatttc tcacgcgttc ccggggtgac ggatgccgtt
    19801 tcaggctatg caaatggtag aggagaaaca accaagtacg aattgattaa ccaaacaggt
    19861 catgcagaaa ccgtccatgt cacctatgat gccaagcaaa tttctctcaa ggaaatcctg
    19921 cttcactatt tccgcattat caatccaacc agcaaaaata aacaaggaaa tgatgtgggg
    19981 acccagtacc gtactggtgt ttattacaca gatgacaagg atttggaagt gattaaccaa
    20041 gtctttgatg aggtggctaa gaaatacgat caacctctag cagttgaaaa ggaaaacttg
    20101 aagaattttg tggtggctga ggattaccat caagactatc tcaagaaaaa tccaaatggc
    20161 tactgccata tcaatgttaa tcaggcggcc tatcctgtca ttgatgccag caaatatcca
    20221 aaaccaagtg atgaggaatt gaaaaagacc ctgtcacctg aggagtatgc agttacccag
    20281 gaaaatcaaa cagaacgagc tttctcaaac cgttactggg ataaatttga atccggtatc
    20341 tatgtggata tagcaactgg agaacctctc ttttcatcaa aggacaagtt tgagtctggt
    20401 tgtggctggc ctagttttac ccaacccatc agtccagatg ttgtcaccta caaggaagat
    20461 aagtcctaca atatgacgcg tatggaagtg cggagccgag taggagattc tcaccttggc
    20521 catgtcttta cggatggtcc acaggacaag ggcggcttac gttactgtat caatagcctc
    20581 tctatccgct ttattcccaa agaccaaatg gaagaaaaag gctacgctta tttactagat
    20641 tatgttgatt aatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat
    20701 gtagggttac tgacttcgtc agttttatct acagcctcaa agctatactt tgagctgact
    20761 tcgtcagttt tatctacagc ctcaaagcta tactttgagc tgacttcgtc agttttatct
    20821 acaacctcaa agctatactt tgagctgact tcgtcagttt tatctacaac ctcaaagcgg
    20881 tactttgaga aacctgtggc tatcttccta gtttactttt tgatttttat tgagtataag
    20941 aggtctttcc taagcagtta gaggagaatt ttgctatact gatactagta agtggtaaag
    21001 gagcagatca tgacctacac aatcttaatc gtagaagatg aatatctggt aagacaaggt
    21061 ttgactaaac tggtcaatgt agcagcctac gatatggaaa tcatcggtca ggctgaaaat
    21121 ggaaggcagg cttgggaatt gatccaaaag caggtgccag atatcatttt aaccgatatc
    21181 aacatgcctc atctaaatgg catccagttg gccagtctgg tacgagaaac ctatcctcag
    21241 gttcatttgg tctttttaac aggttacgat gattttgatt atgccttgtc tgctgtcaaa
    21301 ctaggtgtgg acgactacct gctcaaaccc ttttctcgtc aggatattga ggaaatgttg
    21361 gggaaaatca aacaaaaact agacaaggaa gagaaagaag agcagttaca agatttattg
    21421 actaataggt ttgaaggaaa catggcccag aaaatccagt ctcatctggc tgatagccaa
    21481 tttagtttaa agtctttagc cagtgactta ggttttagtc cgacctatct gagttccttg
    21541 attaagaaag agttgggctt gccttttcag gattatctgg tgagagaacg tgttaaacaa
    21601 gccaagctct tgcttttaac tacagatctg aagatttatg agatcgcaga gaaggttggt
    21661 tttgaagata tgaactattt tacccaacgt tttaagcaga ttgcaggtgt gacacctcgt
    21721 cagtttaaga agggagaaga ccgatgaagc gttcttctct tttagttaga atggttattt
    21781 ccatctttct ggtctttctc attctcctag ctctggttgg aactttctac tatcaatcaa
    21841 gttcttcagc cattgaggcc accattgagg gcaacagcca aacgaccatc agccagacta
    21901 gccactttat tcagtcttat atcaaaaaac tagaaaccac ctcgactggt ttgacccagc
    21961 agacggatgt tctggcctat gctgagaatc ccagtcaaga caaggtcgag ggaatccgag
    22021 atttgttttt gaccatcttg aagtcagata aggacttgaa aactgttgtg ctggtgacca
    22081 aatctggtca ggtcatttct acagatgaca gtgtgcagat gaaaacttcc tctgatatga
    22141 tggctgagga ttggtaccaa aaggctattc atcagggagc tatgcctgtt ttgactccag
    22201 ctcgtaaatc agatagtcag tgggtcattt ctgtcactca agaacttgtt gatgcaaagg
    22261 gagccaatct tggtgtgctt cgtttggata tttcttatga aactctggaa gcctatctca
    22321 atcaactcca gttggggcag cagggctttg ccttcattat caatgaaaac catgaatttg
    22381 tctaccatcc tcaacacaca gtttatagtt cgtctagcaa aatggaggct atgaaaccct
    22441 acatcgagac aggtcagggt tatactcctg gtcacaaatc ctacgtcagt caagagaaga
    22501 ttgcaggaac tgattggacg gtacttggcg tgtcatcatt ggaaaagtta gaccaggttc
    22561 ggagtcagct cttgtggacc ttgcttgggg ccagtgtcac atctcttctt gtctgtctct
    22621 gcttagtgtg gttcagtctt aaacgctgga ttgctccttt gaaggatttg agagaaacca
    22681 tgttggaaat tgcttctggt gctcaaaatc ttcgtgccaa ggaagttggt gcctatgaac
    22741 tgagagaagt aactcgccaa tttaatgcca tgttggatca gattgatcag ttgatggtag
    22801 ctattcgtag ccaggaagaa acgacccgtc agtaccaact tcaagccctt tcgagccaga
    22861 ttaatccaca tttcctctat aacactttgg acaccatcat ctggatggct gaatttcatg
    22921 atagtcagcg agtggtgcag gtgaccaagt ccttggcaac ctatttccgc ttggcgctca
    22981 atcaaggcaa ggacttgatt tgtctctctg acgaaatcaa tcatgtccgc cagtatctct
    23041 ttatccagaa acaacgctat ggagataagc tggaatacga aattaatgaa aatgttgcct
    23101 ttgataattt agtcttaccc aagctggtcc tacaacccct tgtagaaaat gctctttacc
    23161 atggcattaa ggaaaaggaa ggtcagggcc atattaaact ttctgtccag aaacaggatt
    23221 cgggattggt catccgtatt gaggatgatg gcgttggctt ccaagatgct ggtgatagta
    23281 gtcaaagtca actcaaacgt gggggagttg gtcttcaaaa tgtcgatcaa cggctcaaac
    23341 ttcattttgg agccaattac cagatgaaga ttgattctag accccaaaaa gggacgaaag
    23401 ttgaaatata tataaataga atagaaacta gctaactccc agtcaattct gggagtttta
    23461 tgcgtaattg ggcaaacttt ataggttgtc tatcttgcta aaaacaagaa aaaacggtat
    23521 gatagaagag tgacaacaga ggtaacagag atgaacgaga cacagattca aagagaaaca
    23581 cgtcaggtag tggaagatgt tttagaaaag accaatttga agcagggggt cctttttgtt
    23641 ttaggtctat cttctagtga ggtgctaggt ggtcagattg ggaaagaatc cagtcaagag
    23701 attggtgagc tgatagtgga gactatcttg ggtattctag gtagtagagg tatccattta
    23761 gcagttcaag gttgtgagca tgtcaatcgg gctctcgttg ttgaacgtca ggtggcagag
    23821 cagtttgatc tggaaattgt cagtgtccat cctactcttc atgcaggagg ttcggggcag
    23881 ttggcagcct ttaagtttat gcaggatcca gttgaggttg aatttatcaa ggctcatgct
    23941 ggattggata tcggagacac tgcaattggc atgcatgtca agcatgttca ggttccgatt
    24001 cgccctattt tgagagagat tggtcatgcc catgtaacgg cactggctag tcgtccaaaa
    24061 ttaatcggag gtgcgcgtgc gcactatccg caagacgcta ttagaaagtc ttgagaatga
    24121 ataaaggaga taaaagtgtt taaaaaagac cgtttttcaa ttcgtaagat taagggagtt
    24181 gtaggctctg tatttcttgg aagccttttg atggctcctt ctgtagtgga cgcagccacc
    24241 tatcactatg taaataaaga gattatttca caagaagcta aagatttaat tcagacagga
    24301 aagcctgaca ggaatgaagt tgtatatggt ttggtgtatc aaaaagatca gttgcctcaa
    24361 acagggacag aagcatctgt tttgacagct tttggtttgc tgactgttgg gagcttgctt
    24421 ttaatctaca agagaaagaa aattgctagc gtctttctag ttggagctat gggattggta
    24481 gttcttccta gtgcagaggc tgtagaccca gttgcgaccc tagcgctggc tagtcgagag
    24541 ggtgttgttg aaatggatgg ctatcgctat gttggttatc tatcaggtga catcctcaaa
    24601 acgcttggct tggacactgt tttagaagaa acctcagcaa aacctggaga ggtgactgta
    24661 gtcgaagttg agactcctca atcaacaaca aatcaggagc aagctaggac agaaaaccaa
    24721 gtagtagaga cagaggaagc tccaaaagaa gaagcaccta aaacagaaga aagtccaaag
    24781 gaagaaccaa aatcggaggt aaaacctact gacgacaccc ttcctaaagt agaagagggg
    24841 aaagaagatt cagcagaacc agctccagtt gaagaagtag gtggagaagt tgagtcaaaa
    24901 tcagaggaaa aagtagcagt taagccagaa agtcaaccat cagacaaacc agctgaggaa
    24961 tcaaaagttg aacaagcagg tgaaccagtc gcgccaagag aagacgaaaa ggcaccagtc
    25021 gagccagaaa agcaaccaga agctcctgaa gaagagaagg ctgtagagga aacaccgaaa
    25081 caagaagata cacagccaga agtagtagaa acaaaagatg aggctgctaa tcaacctgtt
    25141 gaagaaccaa aagttgaaac gcctgctgta gaaaaacaaa cggaaccaac agaggaacca
    25201 aaagttgaac aagtaggtga accagtcgag ccaagagaag acgaaaaggc accagtctct
    25261 ccagaaaagc aaccagaagc tcctgaagaa gagaagactg cggaagaaac accgaaacaa
    25321 gaagataaaa taaagggtat tggtactaaa gaaccagttg ataaaagtga gttaaataat
    25381 caaattgata aagctagttc agtttctcct actgattatt ctacagcaag ttacaatgct
    25441 cttggacctg ttttagaaac tgcaaaaggt gtctatgctt cagagcctgt aaaacagcct
    25501 gaggtaaata gcgagacaaa agctgaaaaa gttgcagcta atacagatgc taaacaaagt
    25561 gaagtaaatt ctgagactgc aagtcttaaa acagcaattt ctggattaaa tacagataaa
    25621 gttgaactcg aaaatcaact taagattgca cagggaaaaa ctgaaactga tttcagcatg
    25681 gaatcttgga cggttttgag tacagctaaa aataaagctc aggaagtaaa agataacgga
    25741 acagcgaccc aagaacaaat aaacgaagca gagaaaagtt tgaaaacagc ccttgctgac
    25801 ttatctgttg acaaaacagc tttgggaagc gctatcgata cagctaccaa gaaaaataaa
    25861 gagaactata caaatcaaac atgggcagag ttagaaacag ttcttacagc agcaaaatct
    25921 gtaaacacta acgagtctaa acaaagtgaa gttaatgaag ctgttgaaaa attaactgca
    25981 actattgaaa aattggttga attgtctgaa aagccacgtt tgactctatc tattgaaaag
    26041 agagacatag atcgaaaagt tacggtcacg tatactttgg aaaatccagc aaatactcaa
    26101 ataaaatcaa taactgcaac tctgaaaaaa ggagaggaag ttgttaagga ttttgtttta
    26161 acagaagaaa atcttaaaac taatcattta actgctttgt ttgaaaagct agattactac
    26221 aaagaataca ctctatctac ggatatggta tataacagag gaaatgatga tgagacggag
    26281 agtatttcag aagaactaat tcagctgaat cttaagaaac tagaattgaa agatatccag
    26341 acagtctctc tgatgaaatt tgaaaatggt caagaaagtc aggttacaca cttgtctgat
    26401 aaaccgaccg atttgagtaa attatactta aaagttacat catcaacgtc taaggatgct
    26461 gtgttagccg ttagctctat agaagaagag attgttgaaa ataaaaaaat ctttaaaatt
    26521 catgcagata caccagaatt agtagttcgt aagaaagatg gcagtctttc taagggattt
    26581 gactattaca tggagagagt tatccctcat gatggtgata tttattatga ttttaaagac
    26641 ttgatttcag ctatgacatc taatcctaca ggtacgttta ttttagggag agatatttcc
    26701 tcgcgtaatg taaaaccgga tggaaatgga aaatcttata tcaaaggtga atttaaagga
    26761 aaactacttg gtacaaatga taatgttaga cactcgatct ttgacttaga atatccattg
    26821 tttgatacta taaaatcagg agtcgtgaaa gatattgatt tcaagcatgt caatatggta
    26881 ttcccagata gcaatcaagg agataacgta gcaacaattg caagagtaat caaagataag
    26941 acaaaaattg agaatgttaa tgttgaaggt tatctcgagg gtcgagatca tgtagctggt
    27001 ttagttaata atcttgaagg taattccgaa attgaaaata tatcctttac aggaaagatt
    27061 aagtctaaag gtggtaattc tattacagca ggtattgcag gtagaaatat cttatctcgt
    27121 gttaaacgtg cctatgtaaa tgcaaatatt gaagtccttg gttcaacgaa ttcgagtatg
    27181 cttgttgcag taaatggtac aacattgaat gctagtggag gttggggagc ctggggaaga
    27241 cttactgagt ccgttgctaa agggacgtta gaaattaaac gcagtggaca agctggtgga
    27301 gttactgcaa cagtctggcc ttatggagca attgataagg ttgtcagcta tgcaaaagtt
    27361 accaaaggaa aagaattatt tgggtcagat ggtgatttaa ataataattg gtttatgcaa
    27421 aaaattaata atatttttgg tgttcaaggt atcagctcag gtgactcagg gaatgattct
    27481 aagtttaagc gtatttccga ggaagaagca aagcaaaagg ttgcctctta taatattaca
    27541 gctcccaact tgatgagcga ctcaagtctt ttggtagaca gactcaatga aagttggaaa
    27601 aatactgatc aatttgaaag tatacaggat tatcaatccc aaaaccaatt aatttaccag
    27661 aacttgacta aatttactcc ttattacaat aaagaattta ttgttcatga aggaaatgct
    27721 ctcactcctg aacaggaaat attgaagact aagaaaatca aatcgattgt agggttgaaa
    27781 ggaacagagt tcgttgtaga tggcagtgat attgatacta tcatgcttca ttttgaggat
    27841 ggtagtcaga agcgatataa ggtaacctct actggtaagt tttcgataac taatttaccg
    27901 gaatatcagg ttgaagattt aaatgtggtg tatacatcag aacatatagt acatccacta
    27961 gattcgtcac tgataaataa ccttgttgaa gaattgaaaa aagtagaatt gtatacagag
    28021 tctacttacc aagttctagg tattgataaa gataatgcta acaaattgaa tagaactaag
    28081 agattattct tagatgagtc attagatgct gttaaaacac aattgcctac ctttgtaaaa
    28141 acaatgtttg aaaatgagtg gttgcacatc aatggagaat ctagtggagc tgtcgctgct
    28201 ttacgacaaa aaatcatgga taataagacg gctatattgc ttgctttgac ttatatcaat
    28261 cgttattatg atgttaaatt ctcagactat aatattaaaa aactgatgct ctttaaacca
    28321 actttccatg gtgaaaagat tgatctatta gatcgattaa tccgactagg atcatctgga
    28381 gaaaatagat taaaaggttc agaaaatgca gaaacgttca agcagttatt tgctagcgaa
    28441 acgaagcaga aggatttggt gacttattta gactacaatc gctctttgtt gactaattat
    28501 caaacaacag gggaatggtt taaagaaacg actaaggatt atattcaatt tgaggaacgt
    28561 ccatccttag tagaggagat taaagatgcc aaatatcgag tttacgataa tttaaccgca
    28621 ccgtattatc aaggatatat cctacctctc ttaacgttga agaatactca tttagcaatt
    28681 ttatcgaact atagtactat gacatttgtc agccgtgaaa aacgccctaa ttggaaaaat
    28741 gaagattttg ataagtgggt gaaatatgta gcaactgctc atagaaacca tgttgatact
    28801 tggtataaga ttttacctga taatatcaaa ggtaaaatgg ttaaagagaa tgttactgct
    28861 gtttgggaag gattgagcat cccaggaagt gaatgggtag accagaatgc tgtagataga
    28921 aaaggaagag attacgcccc agctcgagaa ttctttaatc ttgtaggtgg tcctatggga
    28981 ggttggtatg cttaccatgg ttatggtgcg catgctggag gaagaaatcg ggttaattat
    29041 gaggtgtttg atgtattaag tgagtatggt atatcggtct ttactcatga attgactcac
    29101 gttaatgata cttggattta cttaggaggg tatggtagac gtgaaaatat gggacctgaa
    29161 gcttatgctc agggattatt ccagtctcct gttccaggtc agccgggttg gggggcgctt
    29221 ggtctcaata tggcatttga aagaaaaaat gatggtgatc taatttataa tgcctcccca
    29281 actcaatttg aaaataggaa agagttagat agttatatga aaaattataa cgatactctc
    29341 atgatggtgg actacttgga aggagatgca gttatctcta aaggtaaaga agctattact
    29401 aaatggttta aaaaagttga acctaaggtt gttagtcaaa cagctcagta tgatacggtt
    29461 cgtcagttga ctgctgaaga gaaagaaaaa ctttctgttt ctagtgttga tgatttagtt
    29521 gatcaaggat taatgtcaga cagagctgta ggaaataata cctataatcc agctgatttt
    29581 gaaacaagtt atattgcgat agattatatg actggtattt atggtggagg aaagaatagt
    29641 gtaggttcac caggtgcctt gatgtttaaa cataatactt tccgtatgtg gggctactat
    29701 ggttttgaag aaggtgttct aggatatgct tctaataaat ttaagcaagc atctagagat
    29761 gaaggtcatg ctggacttag tgataacttt attatttcta agatttccaa aggggaattt
    29821 ttaactatgg aagcatttaa aaagggatat tttaagaaag tagtagaaga gttaaaaact
    29881 aaaggtattc gtcctgttac tatcaatcaa aaaacatata gcacctttga agaattgcaa
    29941 gaaggattta agcaggctgt tgaaagagat ttgaagaaaa atcagttaga tgagagggaa
    30001 acaagaaact tcaaattcca agttttcaga caacttcttc aacaaacaga tagctttaaa
    30061 acttctatct ttagataatc gaaatctctc atctgctttg cggatgaggg ttttcttatt
    30121 ttatgctata cttaaggtat gcatagaaaa acagtgattg attttaggac tttaggggag
    30181 agatatacct ttacccagcc tattaaagag ttgaaaacga gaaatgtaga agaagtggca
    30241 gatttgctgg cacaagtgga aagctaccaa gagcaaggtt attatgtggt ggggtatgtc
    30301 agctacgagg ctgcacctgc ttttgaggaa aaattagcag ttcacaagga tcccctactg
    30361 ggagagtacc tgctttattt tactgttcat gatagcgtag aaacttcccc tattcctctg
    30421 acttatgagg atattgattt gccctcaaat tggcaggaag taacgtctgc agcagactat
    30481 gaaaaggcca ttgcccagat acaccatcac ttgaggcagg gagacaccta tcaggtcaac
    30541 tacaccgtcc aactcaagca aaagttaagt gccaatcctt ttgccatcta caatcgtatg
    30601 gtggtagagc aggaggcggg ctacaatgcc tatgtggaac atgacgagat ggcagtgatt
    30661 tccatgagcc cagagctctt ttttgagcaa aatgatcgcg agttgacaac acgaccaatg
    30721 aaggggacga ctcagcgtgg ggtaactgac caagaagatc ttgaacaggc cagttggttg
    30781 gaacaggatc ccaaaaatcg ctctgaaaat atgatgattg tggacctctt gcgcaatgat
    30841 atgaaccgta tttctgaagt tgggagcgag cacgtggagc gtctgtgcca ggtagagcag
    30901 tattcaactg tttggcagat gacttcgacc atcaagagtc agttgcgaga ggatgtggac
    30961 cttgttgaaa tcttccgctc actctttcct tgtggttcca taacgggtgc accgaaaatt
    31021 gcgacaatgg agattatcaa gaacttggag cctcaaccgc gtggagtcta ctgtggaacg
    31081 attggtctct tgcttccaaa tggacgacgg atttttaatg tggccattcg taccattcaa
    31141 cttcacaaag gtcaagccat ttatggagtt ggcggaggga ttacttggga tagcacatgg
    31201 gaatctgaat accgagaggt tcatcaaaag gcagcagttc tttatcgtaa acaagctcgc
    31261 ttccaactga ttacgacagg ggaaatcagc cagaagaacc tgctgtttga agatcaacat
    31321 ctggaaagac tgagaaaagc tagtcgttat tttgcctttc cttttgatgc agaagacttg
    31381 ggacacaaga ttgaggaaga gtgtcaggat tgtgaagcta atcaagatta ccgcttgcga
    31441 atcagcctta gcaaatctgg agagatagaa gtcaatcgtc aagtattaac ccctctcagt
    31501 acaagctttt gtcaggccca agtctgcctt caggaagctg ctttgaatca atcctttacc
    31561 tactttaaaa ccactcaccg accgcatttg agcctaggag aacaagagaa gatttaccac
    31621 aataagtcag gagaactgct tgaaacctct ataggaaatt tggttctgaa aatcgctgga
    31681 aaactctaca caccgcctat ccgacttgga atcttgccag gaatttaccg tcagcatttg
    31741 ctagaaacag gacaggtaga agagaaagtc ttgaccttgg cagatttaac ccaagcagaa
    31801 gctatttacg gctgtaatgc agtgagaggc ttgtatgaac taagccttga ggagaactag
    31861 atgaaattga tatttttgca tgggttaggg cagtcagcag agtcttggaa agaagttcgg
    31921 aatctactga cagattatcc ttctgaggct atcgagttat ttccttctgg agttagtaac
    31981 tatcaacaag ctaaagagcg agtttatcag cacctagctc aagagacaga accttttgtt
    32041 ttgattggat tgtccttagg tgctgccctg acactagaac tttccagtta cgatttacca
    32101 aatcttcgag ctttgattct gtcaggatgc ccgcttaaat tagcagggaa tatcctattt
    32161 tatcttcagt tgctgatttt taaactactt cccaaaagag tatttgaaaa acagggagca
    32221 gacaagactc ttatggtcgg agtttctgag gaattgaaga cacttgattt aacggatata
    32281 gcagggactt gctcctatcc aaccttacta atttgtggca gcaaagataa accgaatctt
    32341 agttttatga aagctctcca tagactgtta acagattcgc agtttcagat cattcctgat
    32401 ggccctcatg tcttgaataa ggcaaaacca aaggagtttg tagaaaagac cagaagtttc
    32461 cttgaattgc tgaaataagt ttgataaaat aatattgaaa tcgatatcat aattatggga
    32521 gaaagaaatg aataaacgtc tatttttaaa aatgagtctg gtgacgttgc caattttagc
    32581 cttgttttca caaccagttt tggcggaaga aaacatccat ttttcgagct gtaaggaagc
    32641 ttgggcgaat ggctattcgg atattcacga gagagaacct ggttattctg ccaagttaga
    32701 ccgtgatcat gatggtgtgg cttgcgaatt gaaaaatgct cctaagggtg cttttaaagc
    32761 aaaacagtca acggctattc aaatcaacac aagttcagca acaacaagtg gttgggttaa
    32821 gcaggacggc gcttggtact actttgatgg aaatggaaat ctagtgaaaa atgcatggca
    32881 gggaagctat tacctgaaag ctgatggtaa aatggcacag agtgaatgga tttatgactc
    32941 ttcttatcaa gcttggtatt atttgaaatc agatggttct tatgcaaaaa atgcatggca
    33001 aggagcttat taccttaaat caaacggtaa aatggcacaa ggtgagtggg tttatgattc
    33061 ttcttaccaa gcatggtatt acttgaaatc agatggttca tatgctcgca atgcatggca
    33121 aggaaactac tatttgaaat cagatggtaa aatggctaaa ggtgaatggg tttatgatgc
    33181 cacctatcaa gcttggtatt atttgacatc agatggttct tatgcttaca gtacatggca
    33241 aggaaattac tatctaaaat cggatggtaa aatggctgtc aatgaatggg ttgatggtgg
    33301 acgttattat gttggcgctg acggagtttg gaaggaaggt caagcaagta cagtttcttc
    33361 tagtaatgat agcaatagtg aatattctgc tgctttagga aaggcaaaaa gttataattc
    33421 gttattccac atgtcaaaaa aacgtatgta tagacaatta acttctgatt ttgataaatt
    33481 ttcaaatgat gcagctcaat atgccattga tcatttagat gattaacaga tactggtagg
    33541 cgaaaaaatt ccttataatt catttacgca aacctttgca taagtgaatg gattttgata
    33601 tactagtact gtaagcattt tcaattacta cacaatgaaa aaggagaata tgatgagtca
    33661 aaagattatt gggattgacc ttggtggaac ttctatcaaa tttgcaatct taacaacagc
    33721 aggagaaatc caaggaaaat ggtcaatcaa gaccaacatt ttggatgagg gaagtcatat
    33781 cgttgatgat atgattgagt ctattcaaca tcgtttggac ttgcttggat tggcagcagc
    33841 ggacttccaa ggcattggaa tgggatcacc aggtgtggtt gaccgtgaca aagggactgt
    33901 tatcggtgcc tacaacttga actggaaaac ccttcaacca atcaaacaaa agattgaaaa
    33961 agctttgggc attccatttt tcatcgataa tgatgccaac gtagcagctc ttggtgagcg
    34021 ctggatgggt gctggagata accaaccaga cgttgtcttt atgacactcg gtactggtgt
    34081 tggtggtggt attgtcgcag aaggcaaatt gcttcatggt gttgctggtg cagcaggtga
    34141 acttggtcat atcactgttg actttgacca accaatctca tgtacttgtg gtaaaaaagg
    34201 ctgccttgag acagttgctt cagcaacagg gattgtcaac ttgactcgtc gctatgccga
    34261 tgaatacgaa ggcgatgcag ccttgaaacg cttgattgat aacggagaag aagtaactgc
    34321 taagactgtc tttgatctcg caaaagaagg agacgacctt gctttgattg tttatcgtaa
    34381 cttctcacgt tacttgggaa tcgcttgtgc taacattggt tcaatcctaa acccatcaac
    34441 aatcgtcatc ggtggtggtg tgtcagctgc gggagaattc cttctacaag gtgttcaaaa
    34501 agtttacgat gaaaatagtt tcccacaagt acgcacatct actaaattag ctcttgcaac
    34561 tctaggaaat gacgctggag ttatcggagc agcatcactt gtattgcaat aagataatga
    34621 gagaggaaaa tgctaaccta gagttagtaa tgttcctctt ttatttttta tgctatacta
    34681 gttaggacaa tgaatgaggt gagagtaaat gacaaaagca gatacgattt ttaaagagaa
    34741 tattgaacgc attctaaagg aaggtgtttt ctcagagcag gctcgtccta agtacaagga
    34801 tgggactgtt gctaattcca agtatgtaac tggtgccttt tccgagtacg acttatctaa
    34861 aggagaattt cctatcacaa ccttgcgtcc cattgccatc aaatccgcca tcaaagaagt
    34921 tctctggatt taccaagacc agtcaaatag cttagaagtg cttaatgaca agtacaatgt
    34981 tcactactgg aatgactggg aagttggaga cacgggaacc attggtgagc gctatggtgc
    35041 cgttgttaag aaacacgaca ttatcaataa gcttctcaaa cagttggaaa ccaatccttg
    35101 gaaccgccgc aatattattt cgctctggga ttaccaagct ttcgaagaaa cagatgggct
    35161 gctcccgtgc gcctttcaga ccatgtttga tgtccgccgt atagatggag aaatctatct
    35221 ggatgcgacc ttgacccagc gctcgaatga tatgctggtg gcccaccaca tcaacgctat
    35281 gcagtatgtg gctttgcaga tgatgattgc caaacatttt ggctggaagg ttgggaagtt
    35341 cttctacttc atcaacaacc tccatatcta tgataatcaa tttgaacaag ctcaggaatt
    35401 gctccgtcgg gagccgtcaa actgccaacc acgcttggtt ttaaatgttc ctgatgggac
    35461 taatttcttt gatatcaaag cagaagattt tgagttggtg gattatgacc ctgttaagcc
    35521 acagttgaag tttgacctag ctatttaaaa gaatagaaaa aagaagttga gaataatccc
    35581 aacttctttt gtttcttaac gtgatacgcg gcgacgagct gcttttttac ggttttcttc
    35641 gatgaaagct gctttttgct cttctggttc gattactttc tttttaaatg cgtatactgc
    35701 acctgcaacg gcagcgacag ttcctgcgac acctgttaca agacctttag cgaatccttt
    35761 agccatgagt cttcctcctt tatattctca atcagccagc ctcctcaaga ggtcacattt
    35821 ttctgactga cctttttgtg ttataataat agtaacgaaa aaatgggaat ttttcaagga
    35881 aaaaagatga aaacaaaaat aattgtgatt gttggaccga ctgctgttgg aaagacggct
    35941 ctagctattg aagttgcaaa gcgttttaat ggcgaagtgg ttagtggaga tagccagcaa
    36001 gtctatcgag gacttgatat tgggacggcc aaggctagtc cagaagagca ggcagctgtt
    36061 cctcatcatt taatcgatgt tagagagata accgagtctt actcggcttt tgattttgtt
    36121 tcagaagcta agatgactat tgagggtatt cacaaccgtg gcaagctagc cattatcgcc
    36181 ggtgggactg gactttatat ccagagcttg ctagaaggtt accacctagg tggggagact
    36241 cctcatgagg agattttagc ttatcgagct agtttggagc catattcaga tgaggaatta
    36301 gcccatttgg tggatcaagc aggccttgag attccccagt ttaatcgtcg tcgtgctatg
    36361 cgtgccttag aaattgccca ttttggtcag gatttggaaa atcaagagac cttgtatgaa
    36421 ccgctgatta tctgcttgga tgatgaacgt agtcaacttt atgagcgtat caaccaccga
    36481 gtggatttga tgtttgaggc tgggcttttg gatgaggcca agtggctgtt tgaccattcc
    36541 cctaatgtac aggctgctaa aggaattggc tataaggaac tctttcctta tttccgtgga
    36601 gagcagacct tggaggaagc tagtgagagt ctcaaacagg cgacccgtcg ttttgccaag
    36661 cgtcagctga cctggttccg taatcgcatg caggtcacct tttatcagat tggagaatct
    36721 ggtgtacaag accgcatttt aagccagata gaggagtttt tagatgattg aaacggagaa
    36781 aaaagaggag cgagtcctgc tgattggtgt ggaattgcag ggtatggaca gttttgacct
    36841 ctccatggaa gaattggcta gtttagcgaa aacggcaggg gcagtcgttg tagatagcta
    36901 cagacaaaaa cgtgaaaaat atgattccaa gaccttcgtc ggctctggta agttggaaga
    36961 gattgcgctt atggtggatg cagaagaaat cactactgtc atcgtcaaca accgtctgac
    37021 cccaaggcag aatgtcaatc tagaggaagt tctcggtgtt aaggtcattg accgtatgca
    37081 gttgattttg gatatctttg ccatgcgggc tcgaagccat gaagggaagc tccaagtcca
    37141 cctagcccaa ctcaaatacc ttttgcctcg cttggttggt caggggatta tgctcagccg
    37201 tcaggcaggg ggaattggtt cccgtggtcc tggtgaaagc cagctggagc tgaaccgtcg
    37261 tagcgttcgc aatcaaatca cggatattga gcgccagctc aaggtggttg agaaaaatcg
    37321 ggcgactgtc agagaaaaac gtttggagtc tagcactttt aagattggtt tgattggtta
    37381 tactaatgct gggaaatcaa ctatcatgaa catcttgacc agtaagaccc agtatgaagc
    37441 agatgagctc tttgcgactc tggatgcgac aaccaagagt attcatctgg gaggcaatct
    37501 ccaagtaact ttgacagata ccgttggctt tatccaagat ttgccgacag agttggtgtc
    37561 cagtttcaag tcaaccttgg aagaaagcaa gcatgtggac cttctggttc atgttatcga
    37621 tgctagcaat ccttaccacg aggagcatga aaaaacggtt ctctccatca tgaaagacct
    37681 ggacatggaa gatattcctc acttgacgct ttataataaa gcggatttgg tggaggattt
    37741 cacgcctacc caaacgccat ataccctcat ttctgccaag tctgaggaca gtcgtgaaaa
    37801 cttgcaagca ttattgctag ataagattaa ggaaattttt gaagcattta ccctgcgagt
    37861 gcctttttca aagtcctaca agattcatga tttagagagt gttgcaattc tggaagaacg
    37921 tgattatcag gaagacggcg aagtgattac aggctacatt tccgagaaaa ataaatggag
    37981 gttagaagaa ttttatgact gatattaaaa ctttggctct aaagtatgga ggttatacaa
    38041 gtctggacaa ggtctatctg gatcagcttc tagctggtaa aacagagcag gagcagttaa
    38101 cacttattac acctccgcca agtgttgtta atgcctactt tgcagaactc tatcagaaaa
    38161 aaagtcctca ggctgcgacg gattattttg cagaactcag tcaggaactg aatctttaca
    38221 atactgagcc aagtttcacc ctagaaaata agccttttat tcggcttaat ctgtctggta
    38281 aatcctttgg tttttgttat gagagtgacg gctttggtcg gattttctct gaaaatgagg
    38341 agaaaatctc ggatgacttg ctctttgaaa ttgcgcaaat tttctcccat caattagtct
    38401 ttgaagagtc tggtaagatt tacatgaagc ctgtcaagga cgaggaagtt gtcagcctag
    38461 aaagtctcac agctttgact gatttggaaa gattggctga tggtcgaaaa cgtctcaaag
    38521 gctacagcca agaggattta ttgcaagaag ctgctgcttt ttctggcaaa cgctatttcc
    38581 gatcggaaaa ccgcacagcc atgttatata ttgattaatt agaaagtatc gaatggatat
    38641 tcaattttta ggaacggggg ctggtcagcc ctctaaagcc cgcaacgttt caagtctcgc
    38701 cctgaaactt ttggacgaga ttaacgaagt ttggctcttt gactgtggag aaggtacgca
    38761 aaatcgcatt ctggaaacca caattcgacc acgtaaggtc agcaaaatct ttattactca
    38821 tctgcatgga gaccacattt ttggtttgcc aggtttcctt tctagccgtg cctttcaggc
    38881 caatgaagag cagacagatt tggaaatcta cggacctcaa ggaatcaagt catttgtctt
    38941 aaccagcctt cgtgtgtcag gttctcgtct gccctaccgc attcatttcc atgagtttga
    39001 ccaagattct ctgggtaaaa ttcttgaaac cgataaattc actgtgtatg cagaggagct
    39061 ggaccacact attttctgtg ttggctatcg tgtcatgcaa aaggatctag aagggacgct
    39121 ggatgctgaa aaactcaagg ctgctggtgt tccgttcggc ccgctttttg gtaaaatcaa
    39181 aaacggccag gatcttgttt tggaagacgg aactgaaatc aaggcagcag actatatctc
    39241 agcgccacgt ccaggtaaga ttatcactat tttaggagac actcgaaaaa cggatgccag
    39301 tgtgcgtctg gctgtcaatg cagatgtcct agttcatgag tccacttatg gcaagggtga
    39361 tgaaaaaatt gctcgtaacc atggtcactc aactaatatg caagctgcac aagtagcggt
    39421 agaagcaggt gccaaacgcc tcctactcaa ccatatcagt gcccgtttcc tctcaaaaga
    39481 tataagcaaa ctcaagaagg acgctgccac aatttttgaa aatgtccatg tggtcaaaga
    39541 cttggaagaa gtggaaatct agcagtcaca gaaaggataa gtatgcctac tattctcatt
    39601 accggagcta gcggtggtct agctcaagaa atggtcaaac tcctgcccaa tgaccaactc
    39661 atcttgcttg gtagaaataa ggaaaaatta gcccaactct acggaaatta ttcccatgca
    39721 gaattgattg aaattgatat taccgacgat tcagccctag aagctctggt aactgatctt
    39781 tatctccgct atggcaagat tgatgtcttg attaacaacg ctggttacgg gatttttgag
    39841 ggatttgacc agattgctga taaagatatt caccagatgt ttgaggtcaa tacctttgcc
    39901 ctgatgaatc tgtctcgtca ccttgcggct cgtatgaagg aaagcagcaa agggcatatc
    39961 atcaacatcg tcagcatggc aggtctaata gctactggca agtctagtct ttactcagcg
    40021 accaagtttg cggctattgg tttttcaaat gctctgcgac tcgaacttat gccctatgga
    40081 gtctatgtga caacagtcaa tccaggacca atccgtacag gatttttcga ccaagccgac
    40141 ccagatggaa cttatcttaa atcggttgac cgcttcctgc tagaaccaga tgcagtggct
    40201 aaaaagattg tcaagattat aggaaaaaac aaacgagaac tcaatctccc gattttgttg
    40261 aacctagctc ataagtttta taccctcttt cctaagctag ctgataagtt ggcaggggaa
    40321 acttttaatt ataagtaaaa agaaccaatg tgcaggttgt tgctagccta catattggtt
    40381 cttatcattt ctcaactatc aaactgaact tcttctagga ggtagtctat aaagcgttcg
    40441 cccatcttag ataggctggt tttctcatgc tggatataga ccagctcaat cgggtcatca
    40501 atatccagtg ggatagaaac gatattgtct ccgtttaggt tgctgttcaa aatccctgtc
    40561 gcaatggtat aaccatccaa accaatcaag agattaaaga gggtggcacg gtcactgacc
    40621 acaatggatt tcttgtggtg ttcttgagaa agaatctctt ctgaaaagta gaaggagttg
    40681 tgcgtccctt ggtcatagct gaggtaaggg aaattctcca aatcagacag tttcaccttg
    40741 tctttctttg ccagagggtt ggtcttgctg acaaagatat gtggttgcgc tgtgaagaga
    40801 tggtgggcta gcaggtgatt gtcatccagc atcttggtta aaacatcacg gttgtaactg
    40861 tttaagaaga ggaccccgac ctcactgcgg aagttcttga cgtcgtcgat aatctcccaa
    40921 gtccgagttt cacgaaggaa gagttcgtat ttctccatat cgcttttctt gagcaaagag
    40981 acaaaggcat tgaccacaaa ggcatagtgt tgagacgaaa cgctaaatag ttcgcggtgg
    41041 gcgacaggat ttttatagcg ttcctccaga agctgggtct gctcgacaac ctgacgggca
    41101 taggagagaa actccatccc atcacgggtc aaggtgattc ccttgggatt gcggataaag
    41161 atctcaatgc ccatttcatt ttccaaatct cgcactgcat tggagagact tggctgagtg
    41221 ataaagagtt gcttggctgc ctcattcatg gagccagttt cgacgatttt gataatataa
    41281 tgtaattgtt gaattctcat gtttttattg taccatactt gccttagaat cgctaaagaa
    41341 gatgggaaaa taaggagcat tgtgtgagtc tcttcttgaa aaaaacacaa aattttgcta
    41401 gaatgagtct tatgaaaaca ttctatgatg tgcagcaatt cctcaaacga tttggtatta
    41461 ttgtttacat gggaaaacgc ttatatgata ttgaactgat gaagttggaa ctatctcgga
    41521 tttacgatgc agggttgatg gataaattag actatctaga ggcagaagca gttcttcgca
    41581 gagagcacaa ggtagaattg gattatattg agaaaaatgg agaaaagaac taatggttac
    41641 ttggattttg tgggcactta tactagcaat gttggcgtgg atgggcttta actatcttcg
    41701 tattcgccgt gcggctaaaa ttgtggacaa tgaggagttt gaagccttga ttcgtacggg
    41761 tcaattgatt gatttgcgcg acccagcaga attccacaga aaacatatcc ttggtgcacg
    41821 caatattcct tcaagtcagt tgaaaactag tcttgcagcc cttcgtaaag ataaacctgt
    41881 ccttctctac gaaaaccaac gtgcgcaacg agttacaaat gcagctcttt acttgaaaaa
    41941 acaaggtttt tctgagattt atatcctttc ttatggcttg gattcttgga aagggaaagt
    42001 gaagactagc taaccttatt tccaaattag ttgaatgata ggatgaagct attgttttat
    42061 agtataatta atttgtataa aatttaagga gttcttagaa catgaaagaa aagaagaaaa
    42121 tccacttttt gtgggtatct tgtcgattat tcttggtttg ttatttccaa ttgtaggcct
    42181 gattttgggt atcataggat tggtcttggc tatttcatac caaaaagagt cacaattaga
    42241 ctataaaata gaaaagattc ttaatatctt aggaattgtg atttctgtag ttaactggat
    42301 tgtagcaatc gccttaattt ttcggtaaat aaaagaaaaa agctttagtt ttaaagcttt
    42361 ttttatttta tcgactcatc tctaaatagt ttttaatgat ttgtaactct ttttggttca
    42421 aagggcggta gttaccttct gctaaatctg ggttcaatgt gaagtcccca aattggattc
    42481 tcttgaggct agtcacctta acaccaaccg agaggaacat tttcttgatt tgatgaaatt
    42541 ttccttctga aatggtgata gaggcttgac tgatggaggg acttgcagat agaatctcta
    42601 gttttgcggg tttacagaca gtaccatcta aaaagacaat tcccttttga aaggcttgga
    42661 tatggtcagg tgttagaagt ccattaacct caacttgata agtcttatcg acatgatatt
    42721 ggggatggag gagttggaag cccaagggac cgttatcggt caagagaagg agtcctgttg
    42781 tatctcggtc cagtcggccg acggcataga gcttgtcaga ctggatgtca gatggaagca
    42841 ggtccatgac ggtcggaagt tccttgtctt tgttggctgt aacgacacca gcaggtttat
    42901 gaagcataag ataggtgtgt tcatagcctt gaatgattcg atcctgaaaa aggagttctt
    42961 gtagtcctgt atcgatattt tgagctaggg agcgggctgg gcaaccatcg actagaattt
    43021 cccctctgag gagtgcttgt ttcatggcct ttcggctgat tttttcttga gctaataaat
    43081 tatctaaacg catactgtgc ctatcttatc ataagtcgct tgctttgaaa aggcttgacg
    43141 tgaaaagaaa agcggagtga aaacatttac acttgcttga gttatgttat ttatttgaaa
    43201 ttatggtata atcgttcagt tagaaaataa attttgaata ttatagagga aatcatgaca
    43261 aaattaagag aagatatccg taacattgcg attatcgccc acgttgacca cggtaaaaca
    43321 accctcgttg acgaattatt gaaacaatca gaaacgcttg atgcacgtac tgaattggca
    43381 gagcgtgcta tggactcaaa cgatatcgaa aaagagcgtg ggattaccat ccttgctaaa
    43441 aatactgccg ttgcttacaa cggaactcgt atcaacatta tggacacacc aggacacgcg
    43501 gactttggtg gagaagttga gcgtatcatg aaaatggttg acggtgttgt cttggtcgta
    43561 gatgcctatg aaggaaccat gccacaaact cgtttcgtat tgaaaaaagc cttggaacaa
    43621 gaccttgtcc caatcgtggt tgttaacaaa atcgataagc catcagctcg tccagtagaa
    43681 gtagtggatg aagtcttgga acttttcatc gagcttggtg cagatgacga ccagcttgat
    43741 ttcccagtgg tttatgcttc agcgatcaac ggaacttctt cattgtcaga tgatccagct
    43801 gaccaagaag cgactatggc accaatcttt gacacgatta tcgaccatat cccagctcca
    43861 gtagataact cagatgagcc tttgcagttc caagtgtcgc ttttggacta caatgacttc
    43921 gttggacgta tcggtatcgg tcgtgtcttc cgtggtacag ttaaggttgg ggaccaagtt
    43981 accctttcta aacttgacgg tacaactaaa aacttccgtg ttacaaaact cttcggtttc
    44041 tttggtttgg aacgtcgtga aatccaagaa gccaaagcgg gtgacttgat tgccgtttca
    44101 ggtatggaag acatctttgt cggtgaaacc atcactccga cagatgcagt agaagctctt
    44161 ccaatcctac acatcgatga gccaactctt caaatgactt tcttggtcaa caactcacca
    44221 tttgctggta aagaaggtaa atgggtaacc tctcgtaagg tggaagaacg cttgcaggca
    44281 gaattgcaaa cagacgtttc ccttcgtgtt gacccaactg attcaccaga taaatggact
    44341 gtttcaggac gtggagaatt gcacttgtca atccttatcg aaacaatgcg tcgtgagggc
    44401 tatgaacttc aagtatctcg tccagaagtt atcgtaaaag aaatcgacgg tgttaaatgt
    44461 gaaccatttg aacgtgtaca aatcgacact ccagaagaat accaagggtc tgttatccaa
    44521 agcctttctg aacgtaaagg tgaaatgttg gatatgattt caactggtaa tggtcaaact
    44581 cgtttggtct tccttgttcc agcgcgtggt ttgattggat actcaactga gttcttgtca
    44641 atgactcgtg gttacggtat catgaaccat accttcgacc aatacttgcc attgattcca
    44701 ggggaaattg gtggacgtca ccgtggtgcc cttgtttcta tcgatgctgg taaggctaca
    44761 acttactcaa tcatgtctat cgaagaacgt ggtacgatct ttgtcaaccc aggtactgag
    44821 gtttatgaag gaatgatcat cggtgaaaac tctcgtgaaa atgacttgac agttaacatc
    44881 acgaaggcaa aacaaatgac caacgttcgt tcagctacta aggaccaaac agctgttatc
    44941 aagacgcctc gtatcttgac acttgaagag tctcttgagt tcttgaacga cgatgagtac
    45001 atggaagtaa cgcctgagtc tatccgtttg cgtaaacaaa tccttaacaa agcagagcgt
    45061 gagaaagcta acaagaagaa aaaatcagct gaataagagc tagaaagaga gaaagatggt
    45121 ctatttagtc ctaggaattt tactgctcct actctatgta tttgcgacac cagaaagcat
    45181 taaagggact gtcaatatcg tcgctatggt atgtatttta gtggcactct tgattttatt
    45241 ggttctatct tttctgaaaa tttttcaatt accaacagaa atattcctag caatagccat
    45301 gttgatccta gcttacttta gtgttagaga catcacactc atgccagtca aaaaaagtaa
    45361 aagaagataa aaaagagagt ttcggctctc tttttgctag gaattttaca atagtttgaa
    45421 ttgcttttta gttaacacca tctcttttac ttgtatagta tgaatgggaa aaacttgaat
    45481 aaaattcgtt aatggcatct attttatatt tggttagtac tggttgcata ttattttga
//
LOCUS       DAVKMJ010000016        45065 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000016 DAVKMJ010000000
VERSION     DAVKMJ010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45065)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45065)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45065
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.016"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(79..3756)
                     /gene="rpoC"
                     /locus_tag="VW348_000866"
     CDS             complement(79..3756)
                     /gene="rpoC"
                     /locus_tag="VW348_000866"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEU9745793.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGAIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(3789..7400)
                     /gene="rpoB"
                     /locus_tag="VW348_000867"
     CDS             complement(3789..7400)
                     /gene="rpoB"
                     /locus_tag="VW348_000867"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU9745794.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGIAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            7816..7886
                     /locus_tag="VW348_000868"
     tRNA            7816..7886
                     /locus_tag="VW348_000868"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7848..7850,aa:Cys,seq:gca)
     gene            complement(8084..9415)
                     /locus_tag="VW348_000869"
     CDS             complement(8084..9415)
                     /locus_tag="VW348_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEU9745795.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTNTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(9644..10468)
                     /gene="endA"
                     /locus_tag="VW348_000870"
     CDS             complement(9644..10468)
                     /gene="endA"
                     /locus_tag="VW348_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEU9745796.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(10507..10695)
                     /locus_tag="VW348_000871"
     CDS             complement(10507..10695)
                     /locus_tag="VW348_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEU9745797.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(10688..11971)
                     /gene="murA"
                     /locus_tag="VW348_000872"
     CDS             complement(10688..11971)
                     /gene="murA"
                     /locus_tag="VW348_000872"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU9745798.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(11995..12225)
                     /locus_tag="VW348_000873"
     CDS             complement(11995..12225)
                     /locus_tag="VW348_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEU9745799.1"
                     /translation="MVQLLFTLSSHMFFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(12283..13320)
                     /locus_tag="VW348_000874"
     CDS             complement(12283..13320)
                     /locus_tag="VW348_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEU9745800.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(13304..13792)
                     /gene="coaD"
                     /locus_tag="VW348_000875"
     CDS             complement(13304..13792)
                     /gene="coaD"
                     /locus_tag="VW348_000875"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEU9745801.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(13782..14321)
                     /gene="rsmD"
                     /locus_tag="VW348_000876"
     CDS             complement(13782..14321)
                     /gene="rsmD"
                     /locus_tag="VW348_000876"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEU9745802.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAKRELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(14386..15378)
                     /locus_tag="VW348_000877"
     CDS             complement(14386..15378)
                     /locus_tag="VW348_000877"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEU9745803.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTSKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(15490..16173)
                     /locus_tag="VW348_000878"
     CDS             complement(15490..16173)
                     /locus_tag="VW348_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEU9745804.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(16229..16969)
                     /locus_tag="VW348_000879"
     CDS             complement(16229..16969)
                     /locus_tag="VW348_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEU9745805.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSPALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            17003..17281
                     /locus_tag="VW348_000880"
     CDS             17003..17281
                     /locus_tag="VW348_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEU9745806.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            17359..18285
                     /gene="yidC"
                     /locus_tag="VW348_000881"
     CDS             17359..18285
                     /gene="yidC"
                     /locus_tag="VW348_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEU9745807.1"
                     /translation="MKSIKRFALSAMGAAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVHEELAKNPSKASAFST
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(18360..19154)
                     /gene="pflA"
                     /locus_tag="VW348_000882"
     CDS             complement(18360..19154)
                     /gene="pflA"
                     /locus_tag="VW348_000882"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEU9745808.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(19280..20530)
                     /locus_tag="VW348_000883"
     CDS             complement(19280..20530)
                     /locus_tag="VW348_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEU9745809.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGLHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(20597..21424)
                     /gene="purR"
                     /locus_tag="VW348_000884"
     CDS             complement(20597..21424)
                     /gene="purR"
                     /locus_tag="VW348_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEU9745810.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(21691..22632)
                     /locus_tag="VW348_000885"
     CDS             complement(21691..22632)
                     /locus_tag="VW348_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEU9745811.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            complement(22622..23878)
                     /locus_tag="VW348_000886"
     CDS             complement(22622..23878)
                     /locus_tag="VW348_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEU9745812.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(23880..24542)
                     /locus_tag="VW348_000887"
     CDS             complement(23880..24542)
                     /locus_tag="VW348_000887"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEU9745813.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(24505..25161)
                     /locus_tag="VW348_000888"
     CDS             complement(24505..25161)
                     /locus_tag="VW348_000888"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEU9745814.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVANPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTSVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(25172..26050)
                     /gene="rsgA"
                     /locus_tag="VW348_000889"
     CDS             complement(25172..26050)
                     /gene="rsgA"
                     /locus_tag="VW348_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEU9745815.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYQQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFFNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETHKKVSKKIPK"
     gene            complement(26052..26924)
                     /gene="rsmA"
                     /locus_tag="VW348_000890"
     CDS             complement(26052..26924)
                     /gene="rsmA"
                     /locus_tag="VW348_000890"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEU9745816.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFACLADALKGQGL"
     gene            complement(27055..27363)
                     /locus_tag="VW348_000891"
     CDS             complement(27055..27363)
                     /locus_tag="VW348_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745817.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(27356..27997)
                     /locus_tag="VW348_000892"
     CDS             complement(27356..27997)
                     /locus_tag="VW348_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9745818.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRMIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(27999..30029)
                     /locus_tag="VW348_000893"
     CDS             complement(27999..30029)
                     /locus_tag="VW348_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU9745819.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREKVTEALSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSI
                     LGLGILWYQGALFMATVQLVIIALLLYGLILAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQYSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSAYYQGLFTDYL
                     QNFSSESVEVTSQKHYFPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(30298..31197)
                     /locus_tag="VW348_000894"
     CDS             complement(30298..31197)
                     /locus_tag="VW348_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9745820.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPSAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(31269..31829)
                     /gene="rnmV"
                     /locus_tag="VW348_000895"
     CDS             complement(31269..31829)
                     /gene="rnmV"
                     /locus_tag="VW348_000895"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEU9745821.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINAQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMMVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSCKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(31829..32602)
                     /locus_tag="VW348_000896"
     CDS             complement(31829..32602)
                     /locus_tag="VW348_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEU9745822.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(32907..33800)
                     /locus_tag="VW348_000897"
     CDS             complement(32907..33800)
                     /locus_tag="VW348_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEU9745823.1"
                     /translation="MVAQDPKAQDSTKLTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANEGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(34084..34218)
                     /gene="rpmH"
                     /locus_tag="VW348_000898"
     CDS             complement(34084..34218)
                     /gene="rpmH"
                     /locus_tag="VW348_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEU9745824.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(34363..35577)
                     /locus_tag="VW348_000899"
     CDS             complement(34363..35577)
                     /locus_tag="VW348_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEU9745825.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(35733..36027)
                     /locus_tag="VW348_000900"
                     /pseudo
     CDS             complement(35733..36027)
                     /locus_tag="VW348_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            36189..36641
                     /locus_tag="VW348_000901"
     CDS             36189..36641
                     /locus_tag="VW348_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEU9745826.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(36676..38064)
                     /locus_tag="VW348_000902"
     CDS             complement(36676..38064)
                     /locus_tag="VW348_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9745827.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSCDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     SASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            38130..39092
                     /locus_tag="VW348_000903"
     CDS             38130..39092
                     /locus_tag="VW348_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEU9745828.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKNYMEG"
     gene            complement(39121..39279)
                     /locus_tag="VW348_000904"
     CDS             complement(39121..39279)
                     /locus_tag="VW348_000904"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745829.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHVFEVVDETDEVS
                     NHTYGKAT"
     gene            complement(39343..40353)
                     /gene="ccpA"
                     /locus_tag="VW348_000905"
     CDS             complement(39343..40353)
                     /gene="ccpA"
                     /locus_tag="VW348_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEU9745830.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(40778..41377)
                     /locus_tag="VW348_000906"
     CDS             complement(40778..41377)
                     /locus_tag="VW348_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9745831.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(41379..42476)
                     /locus_tag="VW348_000907"
     CDS             complement(41379..42476)
                     /locus_tag="VW348_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9745832.1"
                     /translation="MLERLKSIHYMFWVSLIFMLFPILPVVIGELPAWHLLVDILFVV
                     TYLGVLITKNQRLSWLFWGIMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VEQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     EAMTSMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(42476..43213)
                     /locus_tag="VW348_000908"
     CDS             complement(42476..43213)
                     /locus_tag="VW348_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9745833.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GEPANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(43215..44099)
                     /locus_tag="VW348_000909"
     CDS             complement(43215..44099)
                     /locus_tag="VW348_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9745834.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFILTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(44086..44280)
                     /locus_tag="VW348_000910"
     CDS             complement(44086..44280)
                     /locus_tag="VW348_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745835.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIHGALGFGFM
                     IFVVFPMGMEWLKGESHDGG"
     gene            complement(44277..44483)
                     /locus_tag="VW348_000911"
     CDS             complement(44277..44483)
                     /locus_tag="VW348_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745836.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT        12881 a        10500 c         8550 g        13134 t
ORIGIN      
        1 tttaccacat ttcgtggaaa aatggagaaa gttttcagaa gagagaatga gagaaccctc
       61 gggttctctc attctctctt attctactgt ttcttccaca gtttcaacgg cagtatccac
      121 aactacttct gttgtttctt catttccttc ttcctctact ggaggattaa ggtattcttc
      181 ttcgttgaca gcatgtggtt caaggttacg gtaacgggcc ataccagtac cagctgggat
      241 gatcttaccg atgataacat tttctttaag tccaaggaga tggtctttct taccacggat
      301 agctgcgtca gtaaggacac gagttgtttc ctggaaggaa gccgctgaca agaaactgtt
      361 tgtttcaagt gaggctttgg taattcccat aaggactggg cgacctgtcg ctggaactcc
      421 acctgcgata aggacatctt tgttggcatc tgtaaagtca ttgatatcca tgagggtacc
      481 catgagaaga tctgtatcac ctggatccat gacacggact ttacggatca tttgacgaac
      541 cattacctcg atgtgtttgt caccgatttc taccccttgg ctacggtaaa ctttttgtac
      601 ttcaccgaga aggtacgttt caactgacaa gacatcacga actgcaagga gacgttttgg
      661 ttggatagaa ccttctgtca gagcagcacc acgcgctact tggcccccaa cttcgacacg
      721 catacgagct gtaaatggaa cgacatattc accttcgcca gtttcaccct taacaaagac
      781 tttcttggta cgagttgatg catcttcttc gatagcagta acttgtcctt taacctctgt
      841 aataaccgct tcccctttag gattgcgggc ttcaaagatt tcttggacac gaggaagacc
      901 ctgagtgata tcggtatttg aggcaacccc acctgtgtgg aaggtacgca ttgtaagctg
      961 tgtaccaggt tccccgatag attgggcagc gattgtacca actgcttcac caacttcaac
     1021 cgcatcacca gtcgccaagt tgataccgta acagtgacgg cagacaccgt gacgagtgtt
     1081 acatgtaaat acagaacgga tagtcacttc ttccacacca gcattgacaa tttcacgcgc
     1141 cttgtcttct gtaatcaatt catttggacc aataatcact gcaccagttt ctggatgttt
     1201 aacagttttc ttagtgtaac gaccgttgag acgctcttcg agagactcga tcatctcttt
     1261 tccttctgcg atagaacgga tcaagagacc acggtcagtt ccacagtcgt cctcacggat
     1321 gataacgtct tgggcaacgt cgaccaaacg acgagtcaag taacctgagt cggctgtctt
     1381 aagggccgta tcggtcatac ctttacgagc accgtgagtt gagaagaaca tttccaatac
     1441 cgacaaacct tcgcggaagt ttgaaaggat tggcaattcc atgatacgtc cattcggagc
     1501 agccatcaga ccacgcatac cggcaagctg tgagaagttt gagatgttac cacgggctcc
     1561 agagtccatc atcataacga ttgggttctt aggatcttga ttagcaatca agcgtttctc
     1621 aagtttttca cgggcagcac gccattcagc tgtaacagca ttgtaacgct cgtcgtctgt
     1681 gatcatacca cgacggaatt gtttggtgat ttgttcgaca cgtttgtgtg attcttcaat
     1741 gatttcagcc ttgtcatcaa cgactgggat atcggcaata cccactgtca atcctgcaag
     1801 agttgagtgg tggtaaccga ggttcttcat gcggtcaagt agggcagaag tttctgtcgt
     1861 acggaaacgt ttgaagattt cagcgatgat atttccgagg tttttcttct tgaatggagg
     1921 gttgagctca agattgctga tagcttcctt gatagctcca ccaagtggca agaagtattt
     1981 agctggaaca ccttctgtca agttggcatt gtttggttct tgcaagtatg gtagcccctc
     2041 tggcatgata tcgttgaaga gaattttacc aactgttgta agcaagacct tatgtctttg
     2101 ctcttctgtc caaggcttgt tgaggctgtc tgttgcgata ccaacacgtg agtggaggtg
     2161 aacataacca ttgcggtaag ccataaccgc ttcgtcacgg tctttgaaga ccattccttc
     2221 accttcgcga ccagcttctt ccatggtcaa gtagtagtta cccaaaacca tgtcctgaga
     2281 tggagtaact accggtttcc catctttcgg gttcaagatg tgctcagcag ctagcatgag
     2341 gatacgagct tctgcttgtg cttcttctga aagtggtacg tggatggcca tttggtcccc
     2401 gtcaaagtca gcattgtagg cttcacagac aagtgggtgc aagcgaagag ccttaccatc
     2461 aattaagact ggctcgaagg cttggatacc caaacggtga agggtcggtg cgcggttcaa
     2521 aagcactggg tgttctttaa tcacttcttc aaggatatcc cagatacgct catctccgcg
     2581 ttccaccaag cgtttagctg ctttgacgtt ttgcacgata tcacgggcaa cgatttcacg
     2641 catgacaaat ggtttaaaga gttcaatcgc catttcacgt ggcacaccac attggtacat
     2701 cttaagagtt ggaccaacgg cgataacgga acgtcctgag aagtcaacac gtttaccgag
     2761 caagttttga cggaagcgtc cttgtttacc tttaagcatg tggctcaatg atttcaatgg
     2821 acggctacct ggtcctgtga ttggacgacc acgacgacca ttgtcaatca aagcatcaac
     2881 tgcttcttga agcatacgct tctcattttg aacgatgata cctggtgcat ttaactcaag
     2941 caaacgagcc aaacggttgt tacggttgat aacacggcgg taaaggtcat tcaagtcaga
     3001 tgaggcaaaa cggccaccat ccaactgcaa cattggacga agatctggtg ggataaccgg
     3061 aaggatgtta agaatcatcc attcaggttt gtttccagac ttgtaaaagg catccaaaac
     3121 atccaaacga cggatggctt tgacacgttt ttgtccagta gctgttttca attcttcttt
     3181 gagttcagca atttcttttt caagatctac ttgcttcaaa aggtcttgga tggcttccgc
     3241 acccatcttg gcaacaaatg aaccataacc atattcacgc aagcgctctc ggtattcgcg
     3301 ctctgtcatg atagacttgt gctcaagtgg tgtatcctta ggatcaatca ccacataagc
     3361 cgcaaagtag ataacttcct cgagggcacg agggctcata tcaagggtca agcccatacg
     3421 gcttggaatc cccttgaagt accagatgtg agatacagga gctttcaatt cgatatgtcc
     3481 catacgctca cgacgaactt tcgtacgcgt tacttcaacc ccacagcggt cacaaacaat
     3541 tcctctgtaa cgaatgcgtt tgtacttacc acaagcacat tcccagtctt ttgtaggacc
     3601 aaagatcact tcatcaaaga gtccttcacg ttctggtttc aaggtacgat aattgattgt
     3661 ttcaggtttt ttgacttctc cataagacca tgaacggact ttacttggag aagctagggt
     3721 gatttgcata cttttaaaac gatttacatc aaccactatt tcttcccttt ctattctaag
     3781 tgaactgctt attcttgttc agcagcttct tctgttgctt ccgcttttgt tgctttctca
     3841 gcttcttcag cttcaaaggc tgctttagcc tcttgggctg ctttttcgcg ggctttttca
     3901 aggtcatcta cgtggatgac atcttcgtcc attccttcat ccaagtcgcg aagttccact
     3961 tcttggtcat cttcgtctag gacacgcatg tcaagaccaa gagattgcaa ttctttgaca
     4021 agaactcgga aggattctgg aacacctggt tttggaattg gtttgccttt tgtaatagct
     4081 tcataggctt tcaaacgtcc gttgatatcg tccgacttgt aagtcaagat ttcttgaagg
     4141 acatttgacg caccgtaggc ttcaagagcc caaacctcca tctcaccgaa acgttgtcca
     4201 ccaaactgag ctttacctcc gagtggttgt tgggtaacag ttgagtaagg tccgactgaa
     4261 cgcgcgtgca atttatcgtc aaccatgtgg tggagtttga tcatgtacat gactccaaca
     4321 gaaacacggt tatcaaatgg ttcacctgta cgtccatcgt aaaggattgt cttggcatcg
     4381 ctatccatac ctgcttcttt aacagttgac caaagatctt cagaacttgc tccatcaaag
     4441 actggtgtcg caatgtgaat accaagagta cgagctgcca taccaaggtg aagctccata
     4501 acctgaccga tattcatacg tgatggcacc ccaagtgggt tcaacatgat gtcgactgga
     4561 gttccgtctg gaaggtaagg catgtcttct acaggaacga tacgagagac aacccctttg
     4621 tttccatgac gtccggccat tttatctccg accttaatct tacgtttttg agcgatgtaa
     4681 acacgaacca acatgttaac acctgattgc aactcatctc catttacacg tgtaaagatc
     4741 ttaacatcac gaacgacacc atcggcaccg tgtggtacac gaagagaagt atcacgcact
     4801 tcacgagact tgtctccaaa gatagcgtgc aagagacgtt cttcagctga aagatctttc
     4861 tcacccttag gtgttacttt acctacaaga atatcacctt ctttaacctc agcaccaata
     4921 cggataatcc ccatttcgtc aaggtctttg agggcatctt caccaacgtt tggaatttcg
     4981 cgagtgattt cttcaggccc aagctttgta tcgcgcgttt ctgattcgta ttcttcaagg
     5041 tgaacagatg tgtagacatc gtccttcacc aagcgttcgc tcatgataac ggcatcctcg
     5101 aagttgtaac cttcccaagt catgtaggca acgattgggt tttgtccaag cgccatttct
     5161 ccattttcca tagaaggtcc gtcagcgatg aaatcgcctt tttcaacgac atcaccaact
     5221 tttacgagag tgcgttggtt gtaagcaata cctgagtttg aacgacggaa tttttggatg
     5281 tggtaaacat ccaatgaacc atcttcacga cgaacttcta ccttgtcagc atctgcgtaa
     5341 gtaactttac catcatactg agcaatcaca gccgcaccag aatcgtgggc tgcttggtat
     5401 tccataccag taccaacgta aggtgcctga ggattaatca atggcacagc ctgacgttgc
     5461 atattggctc ccatgagggc acggttggag tcatcgtttt ccaagaaagg aatacatgct
     5521 gtcgcaacgg caactacctg ttttggtgaa acgtccatgt agtcaacaat attagctgga
     5581 tactcttggt tgaccccttg gtgacgtccc atgacaatct tctcagcaaa ggttccatct
     5641 tcattcagac gagagttagc ctgagctaca gtatattcat cttcttcatc agctgtcaac
     5701 caaacaattt cgttcgtgac aacacctgtt tcacggtcaa ccttacggta tggtgtttga
     5761 acaaaaccat atttgttcaa gtgtccgtaa gatgacaagt tattgatcaa accgatgtta
     5821 ggtccttcag gtgtttcgat tggacacata cgaccatagt gagtgtagtg cacgtcacgc
     5881 acttcatatc cggcacggtc acgagtcaaa ccaccaggtc ctaaggctga caaacggcgt
     5941 ttgtgagaca actcagaaag cgggttgtgt tggtccatga actgtgacaa ctgtgatgaa
     6001 ccaaagaatt ctttaactgc agctgttaca ggacggatat tgataatttg ttgtggtgtc
     6061 aagacttcat tgtcctgaac agacatacgt tcacggacat tacgttccat acgagaaagt
     6121 cccaaacgta cttggttggc aagcaattca ccaaccgcac ggatacgacg atttccaagg
     6181 tggtcgatat catctacacg gccaagtcct tcagccaagt tgaggaagta gctcatctca
     6241 gcaaggatat ctgcaggagt caccgtacga accttgtcat ctgggttagc attaccaatg
     6301 atcgttacga cgcgatctgg atcagttgga gcaacaacct tgaatttttg aagaacaaca
     6361 ggctcagtca caacggctgc atcgtttggg atgtagacaa tcttgttcaa gtcgccatcc
     6421 aaatggcttt caatgctttc aatcacgcta cgagtcataa tcgtaccagc ttctaccaag
     6481 atttctccag tttcagggtc taccaatggc tctgcaatgg tttggttgag caaacgtgtt
     6541 ttaacattga gttttttatt gattttgtaa cgaccaactg ctgccaagtc atagcgacgt
     6601 gggtcaaaga agcgagccac aagcaagcta cgtgagcttt cagctgtctt aggctcacct
     6661 ggacgaaggc gttcgtaaat ttctttcaag gcttcgtctg tacgagagtc cattggattc
     6721 ttgtggatat ctttttcaac agtgttgcga accaattcgc tgtcaccaaa gatatcaaag
     6781 atttcatcat cacctgagaa accaagagca cgaaccaagg ttgtaaatgg aatcttacga
     6841 gtacggtcga tacgagtgta ggtgatatct tttgagtcgc tttcaagttc caaccaagct
     6901 ccacggttag ggataacagt tgaaccatag cccaccttac catttttgtc tactttgtcg
     6961 ttaaagtaaa cacctggtga gcggaccaac tgagaaacga taatacgttc accaccattg
     7021 atgatgaaag tacccatttc tgtcatgatt gggaaatcac caaagaaaac ttcttgggtc
     7081 ttgatttcgc ctgtttcttt attgatcaaa cggaaggtta caaaaattgg tgctgagtag
     7141 ctagcatcgt ggatacgagc ttcttctagc gtgtattttg gttccttgat ttcatatcca
     7201 acaaattcca actccattgt gtctgtgaag tttgaaattg gcaatacatc ttcaaacact
     7261 tccttaagac cgtggtctag gaaagctttg aatgagtcag tttgaatttc aatcaaattt
     7321 ggtaagtcaa gaacttcttt gattcttgaa aaactacgac gggtacgatg tttcccgtat
     7381 tgaacgtcat gtcctgccaa gatgattctc ctttgtaaat aagttccaag ccttgtcaat
     7441 caggcttttc taatcgtcat atggttgtaa accccttatc accgtgtcct cttgacgaat
     7501 tttcagaatc tttaagcctc tgttacaaat gctcataatc ttgaaaaaaa gcacaaaaag
     7561 agcagctaaa tctgactttt tcagaagatt taactgctgt gagccttgtc tggacaatat
     7621 ttcagacaaa acctacgaca aatgattacc catattatac cctatttagc tagatttttc
     7681 aaggggtttc agtaggtttt tggtaaattt tttcccatag aaaacttggc atcacattcg
     7741 aatcacgcta tggtacaaaa aactgaaaaa actattgact gaaaatcatt ttcaaggtat
     7801 aataataaac gttaaggcgg tatagccaag tggtaaggca cggctctgca aaagcttgat
     7861 cgtcggttca aatccgtcta ccgccttcta taacttgatt tatcaggttt caaatgaaca
     7921 gaaagcccaa tttgaagggc ttttcttatt ttccctcgaa taaatacgta taactttaaa
     7981 aacttttgga gcgagtttgt ggcagagttc tttccatggc ataattccct tttgaaatca
     8041 attgaaaaaa gcttcgtcac gcctggtgac aaaagcctct agtttattct gtttcttctt
     8101 ctatttcgac ttctgtgatt tggactttta ccttggtaac acgtccattc ttcactttat
     8161 cattggttaa gataaactgt ttgttttggc tgaccaattc atagctgagt ttctcagtcg
     8221 ttggaatagt tcccactcct gtcaaataat aaccagcgat ggtatcaacg tcatcacttt
     8281 ccagttcaac atcaaagtaa ttattgaaat cattgagggt catagttcct tgaacaatgt
     8341 aggtatcctc gccaatctga tgaacatcta ttgctgcttt gtccgtttca tcatcaattt
     8401 caccaacaat ttcctctaag aggtcttcca aagtcaccaa accagccata ccaccgtatt
     8461 catccagcaa gattgccatt tgtctttggg tatttcgcag ttcttttagc aagtcatcca
     8521 caaaaatagt ttcaggtaca aaaagtggat cttgtaaaat tctcttccaa acaatattgt
     8581 caaaaccgtc cacaaagcct gccttaagga gactcttggt gtgaatgatt ccaattacat
     8641 tgtccttatc cccatcataa accgggatac gagaataatt ttgttttaaa atactttgga
     8701 taatggcttg actatcatcc tgaatatcca ccataaaggc atccgttcga ggcaccataa
     8761 cctctcgtgc catcagttca tcgagcgaaa agacaccttg tagcatctca atctcatcag
     8821 catccaatgt ttcttcacta tttgtcagca tataggcaat ttcatcacgg gtcatctttt
     8881 catccgcatc atcgaatgac ataggagtca aatggctcaa gaaattggtc gaagcagcta
     8941 aaagccaaac aaaaggactg actagttttc cgatcccaat gataatcggc gctgtacgaa
     9001 ttgccaaggc atcctttaga ttaagagcga ttctcttagg atataattcc ccaaaaacga
     9061 tggaaatata ggtcaaaaat gccaaggata gaaaagttgc cacggcttgt gctgtttcgc
     9121 cattcccaag ccaagaggca atcacacgtc ctagagtatt agttaaactc gcccctgata
     9181 agattgtaat cagggtgatt cctacctgaa tggttgataa aaagtggtta ggattttcta
     9241 gtaccttcag caggcggatg tagcgtctgt ctccttcttc cgccttttgt tcaactcggg
     9301 cacgattaag agaaaccatg gccatttctg tggctgagaa aaaggcattt aataccgtca
     9361 agataaacaa taaaacaaat tgtagcaaca aattctgact acttgggtct tccatagttc
     9421 ttctcctaaa atagtatctt atcctttatt atatcacaaa atttaatcca atacatatta
     9481 ttttttctta ccgtaacttc tcaaagtaac ttccatctct ctcccaaaac tggaagttag
     9541 ttttagaagt tgctattttt tcttagtacc tgttctagcc ctgcttaaac tagtaaaaag
     9601 aactcctaca tccataagtg acataggagt ttaggcttat cttttactga gttacagtta
     9661 cttctccagt tcggtaatcc agttgaagtc ccttttgaac attgggaact agaacattga
     9721 attccaattc tccatccgaa gacttggctt caatctgtga agctgaggga actaaatcct
     9781 cgtttgaagc gtagtaaagg gttacacggt aacggacacg cttgttttgg tccaaggctt
     9841 tacgcacctt gctttcatag tagttttgac cagtcgaata ctcggcttgt gcctgatttg
     9901 cccaggctgt ctgaacagca atgtttttag gattgcttgt tgaggcatca aaaccatcca
     9961 aaccaccgat taaggcatag cctaacaaat gacctctatc gactgcatgg gtataagagc
    10021 cctttagatt cttgacctga tgccaacctg gaggagtcca agaagttgaa ccattcccag
    10081 tttctttacg attcttgtac tgacgagtgg ccttagacaa gagggcatta gctacggttg
    10141 gaacagtttc cttgcccact gtctttgttt tattgtcagc gtagggctta cttgaaacct
    10201 tggcatctag atttgtttta ttaccattga cgataaaagc acctgagcca ttccactcca
    10261 gactcccctt tatttgactc ttgactgcgt ctgttaagac actctctgcc aatgcttgac
    10321 taggagcttc agacgcttgt tttttctgac taagattggt tttgggacta ttaggtgccg
    10381 acggcatctg cttgatataa tagctccctg tagacaaaag caataacact agcagtccga
    10441 ttagtgtctg tcttgttttt ttgttcatat ttctccttat ctttagaaaa aggctggttc
    10501 tccagcctaa tttcctgtaa atttatgaat caattcctgc cattttgctg gagacaggat
    10561 agcccatgga tcttgaccct tgcccaagat tccataacct accattaaac cgattcctag
    10621 agccagagta cctaaaatca gtactatgat gactaaaagt aaacgcttga ctacgtagct
    10681 tgatttctta ttcatcttca tcacttgcct caatccgctg aatcttagca cctagctgcg
    10741 ccaacttctc atggaaaccg tagtaacctc tatccaagtg aaccaattta ccgaccacag
    10801 tttctccctg tgctaccaaa cctgtcaaaa tcaaggctgc actggcacga aggtcagttg
    10861 aaagaacttc tgctccctgc aaaggctgtc caccaacaat acgagctgta tcacggataa
    10921 tctcagaatg caagcccatg cggcgcatct cttctaggtg ttggaaacga ttttcgaaaa
    10981 ctgtctccac catggttgat tcgccttttg caactgtcat caaggctgta aattgagcct
    11041 gcatatctgt tggaaatcct gggtggggca aggttttcac atgaacagct tttagatttt
    11101 ctagttgaga acgaacacga attccttcgt cttcttcaat tacttcaaca cccatttcaa
    11161 gtaacttggc aatcaaggga cggttgtgct cccagacagc gtctcgaatc aagacatcac
    11221 caccagtcat ggcagcagct accataaagg ttcctgcttc gatacggtct tggactacat
    11281 tgtgagtcgt accatgaagt ttctcaacac cagtaatggt tatagtctct gtaccagcac
    11341 ctttgacctt ggctcccatt tcattaagga gaatggctaa gtcaacaatc tcaggctcac
    11401 gcgcagcatt ctcaatcact gtcaccccat cagccagagt cgctgccatc atcaagttct
    11461 gcgttgcacc aacacttgga aagtccatat agatatgagc gccatgcaag cgttctgcct
    11521 tggcttcgat gtaaccagct gtctgactaa tcttaacccc catagcttcc agacctttca
    11581 aatgaagatc aataggacgg ctaccaatcg tacaaccacc tggcatggat accttggcat
    11641 gacccacacg ggcaaggatt ggccctaata caacgatgga ggcgcgcatc ttgctgacat
    11701 acttgtaagg ggcttcctca gtgatgtcgc cagtagcatc caccttgaca agatgagctt
    11761 cctcatcaaa gtcaaccttg gcattcaaac caccaactac ctgattcata ataaagacat
    11821 ccgacaaaat cggaacattc tgcaagacgg tctttccttc acttgctaga atagtcgctg
    11881 ccaacaaggg taagactgca ttttttgctc cctcgatcgt cacgcttcct accagacgat
    11941 tatcgccacc ttgaaccaca attttatcca tactcgtttc ctttactctt gatttcataa
    12001 taatcctcta agcgcttctt gccacaaatg atacaggcta ataaagaaag aactcaggat
    12061 gtagcctatg acaatgctaa aaaaggctac taataaacga acttttcttg tattatcatc
    12121 tgtcactttt aaaaccttct cccatctaac aagatccttt aaaaggtaaa aactcacata
    12181 aataaagaac atatgactac ttagagtgaa taataattga accatttgac tattatacca
    12241 tcttctctgt ttgtgcgcta gtttggaaac ttcactcaaa aattagggat tgtttttcaa
    12301 gtaatcaatc gcatcttgta gggttttaac gggcacgatt ttcatatccg tcttgattgt
    12361 tttagccgct tctagggctg tttggtagtt gtttttcgcg tccggatgcg ccttttgttc
    12421 ttcttcgcta acagggttat caggagcaaa gaaaatagca gcacctgccc tagccgaagc
    12481 tacaaccttc ttatcaatgc ctccaatgtc tcccacatta ccatcgcggt caatggtacc
    12541 tgtaccggca acaatacgac cattacgaag atctgggtga gctatttgag tatagatagc
    12601 tagactaaac atgagaccag cacttgggcc gccaatacca gctgttgaaa agctaattgg
    12661 gacattgctg attacctctg tacgatcaat caagccgatt ccaattccat ttttgccatt
    12721 ttccaaggtg ataatctttc cttctgcaga cttggtttgc ccatcctctt cataggtgac
    12781 cttgacggaa tcccctaatt tttgagaact gacgtaatca atcaagtctt tggaactatc
    12841 aaaggtctga tcattgactg ctgtgactgt atcagagata ttgagaatcc ctttaaaggt
    12901 tgaattatcc gtcacattca aaacataaac tccaaagtac ttgagttcga tatccttacc
    12961 agctgttttt agtccttgat acttggccat attttgcgat gtttgcatgt agaattgatt
    13021 gattcgcata aattcaacat cggaagaacc acctgtagtc tcctgagcac tacgaatatc
    13081 tgtaaaaggt gtcaaccaag cataaatcat atgagctaaa gtggcatgtt gaacaccaac
    13141 cgtaacgaat tgataggcac cagcttcctt atcttctgtg tcatttactt taaggacttg
    13201 gcgaatatct tccgaaccac ctggaacctc tatataataa ggcaagggca ctacaaatgc
    13261 caagaaagtc acaatcaagg ccgcaatgac gtataagggc catctaatct tttttttcat
    13321 ttcttatttc ctccaaaata ctctcgggaa catggcaggc aatatcctga ccaaacttca
    13381 aaagctctcg aacacctgat gaactgatat agagatgttc aggccggcta tgtaaataaa
    13441 tagtctctat atcagaagac agctgatgat tgtagtaatc aaaactagct tcatattgca
    13501 aatccgccgc attcctcaac ccccgtacta ggaaagtagc ccccagtctt tttgcaacat
    13561 cgaccaccaa ttcatcatga gaagccacga cttcaacatt ttccaaatgt cccaaagcct
    13621 tttctagccc ccgtttacga ttttcaagag ggagaaatcc ttgtttgtgg ggattaaaaa
    13681 aaatacccac ataaagctta tcaaaaagtc tgctcgcccg ttcaatgata tccagatgcc
    13741 catttgtcat cggatcaaat gagcctgtga ataagccaat cttatctgac atagactgtc
    13801 accttactaa ttccataaat cttttccttc cagataccca gacaggcaat ctcttctgga
    13861 agttcaacgg ccttatccgt ctcgcacaca accataacat cttcagaaaa aagctctctc
    13921 ttagccattt tttcaatatc tgctacgatt tgttccttgg catagggagg gtctaagaaa
    13981 acgaggtcaa attccccaga tacctgttcc aatgccctct ctgcatccat cttgaggagt
    14041 tgaaattttc caacttcctt ggtcatctgg atattttcag ccacgatggt ctgagcctta
    14101 cggtctcgct ccaccaaaac agcactggac atgccacgcg atactgcttc gatagataaa
    14161 ccaccactac ctgcataaag gtccaagact cgtccccctt caaagtaggg accaatcatg
    14221 ttaaaaatgg ctcccctaac cttatccgaa gtaggtcttg ttgtcttgcc ttctagtgtc
    14281 ttgaggggac gtcccccata gattcctgat acgattttca tactgtttat tataccaaat
    14341 tatagacaaa aagagaaaga aaaccgaacc ttgcggttcg attctctaca aaatattttc
    14401 gtaagtatcg cgtacttctt gaggccaaac acttgtttgc acttctccga tgtgtctctt
    14461 gcgaagtagg aacatggcca tacgagattg tccaattcct ccaccgattg tcaatgggaa
    14521 taggccattc aacaaagact tgtgccattc caattccaag cggtcttcat cacctgtaat
    14581 ttccacctga cgtctaagag tttcttcatc tacacgaatt cccatagaag acaactcaaa
    14641 ggctccacct aaagactcat tccagacaag aatatcacca tttagaccct tgtagccatt
    14701 ctcagactcg cttgtccagt catcatagtc tggtgcacgt ccatcgtgcg gtttaccatc
    14761 tggcaactcg ccaccgatac caatcaaaaa gacggctcca aattctttac aaatcgcatt
    14821 ttcacgttct ttcgatgtca agtctggata gcgttctacc aattcttctg tatggataaa
    14881 ggtgatttgt tttggcaaga tagactcgat gtcatagcga gcttcaacag ctagctcagt
    14941 caggcgaata gccttataaa tcttctcaac tgtttctttt agataaacga tgttacgctt
    15001 accatttggg ataaccttct cccagtccca ctggtcaaca taaacagagt gggttgcatc
    15061 caaggaatcc tcatctggac gaagggcttt catgtggaca aagagaccct ctccttcacc
    15121 aaagccaaaa cgagccaagg tgtggcgttt ccatttagca agtgagtgca ccacttcata
    15181 agtagcatca gggatttgga gaaccttgac cgatactgga ttttccacac cagacaggtt
    15241 gtcctgcatt ccgtcaccga ccttactcaa gataggacct tgaacttcga caacttctag
    15301 cttatctttc aaatactggg taaaagtgtt tttgacaaag gaaatttctt cttgttgatg
    15361 gataaaactt ttcttcatag acaactcctc aaaaatttaa taaacgtatt atacacctat
    15421 ttccaagaaa agaaaagaga aaatttaaaa aaaatcagtg tcactcaaaa cactgatttc
    15481 atagaccttt tagtcattgc gaccaaagat acgtagaata cttaggaaaa gattgataaa
    15541 atcaagatag atgctgagag ccattgacac cacccagcct gtcgctacac gaccttgtga
    15601 ttgttcatag gcgaggcgaa tcttttggtt atcccaagca atcaaccctg aaaaaaccaa
    15661 aaccatggct acactaatca tataatcaaa gaagccacta gccaagaaaa tattgactac
    15721 catagcaatc agtaaaccaa tgagagctgc catcattgct cgaccaatcc cactcaagtc
    15781 tttcttggta aagataccaa ctgccgccat gacaaagaag agaagggcgc tcgatacaaa
    15841 ggcagataaa actgtacccg gagtatagaa agccaccaca aaactaaggg taaagccgtt
    15901 taaaacggag taaagtaaaa atactggaag agcagctgga ctatttcttg aagccatgct
    15961 actggcaacg aaaaccaaag ccaactccgc aaaagtagca atggtcaacc agagacgccc
    16021 ctgcatcaac aagtaaacca actgagactg aaagaccgtc aacataaggc ctgataccaa
    16081 agcagatagt ccgattccca gaccaacaaa ggcataaacc ttagcgtaaa attgattgag
    16141 acctgcacgg tcatgtataa tagtgtgatt catccttttc tccttttctg tgaacatctt
    16201 tccttgatta taacaaaaaa agttaaaatt agcttaaatg gaagattaaa ataccggctg
    16261 caactgcaac attcaaactc tcggcctgcc ccttcatgct aatatggacc aactggtctg
    16321 cactttcagc cataagggga ctaattcctt gaccctcatt tcccataact agtacaaaat
    16381 tttctataga aggcagttct ctgtaatcaa cagaatcttt agatagggtt gttgctagca
    16441 ctgggatagc taccttttta gtttcgtcaa gaagcgctgg actagtcatc cggtaaatgg
    16501 gcagatggaa atgactacct tgcatggaac gtagggtttt gagactgtag atgtctgccg
    16561 acttatctga aacaatcact cctgtaaaac ctgctgcatc cgcagttcga atgatagttc
    16621 ctacattacc gggatcttgc acatcttcca aaaacaagaa cttgccctga ctcaaatcag
    16681 cttgtcctac ttcttctttt tgaaccaccg ccacaattcc ctgtggagtc tgagaatccg
    16741 ccaaatctag caaaatatcc tctgaaatcc agacagtttg cggaaaagca gctaactgat
    16801 ctcgataatt ttctagggca aagattttct caatcgtcac tccagcttgg acagcttctt
    16861 caaacaagtg ccagccttca atcaaatagg cagacttgcg gtattttttt tggtgtaatt
    16921 tcttggcatt ttttaccaca gaattggctt ttgaggttat aatagtcata gaaatattat
    16981 aacacaatca aaggggtttg gtatgcaaaa ggttagaatg attgcccaag gtagggtaca
    17041 gggagtcggc tttcgttggg gtgtttacag cttggcactt gaaattggtg gcatcacagg
    17101 tcgagtatgg aataacgacg atggcacagt ggaaatctta gcccaagcag actcatctgc
    17161 tatcatggca aaatttatcc aagaaatccg aaaaggaccg acaccttttt caaaagtaag
    17221 ctacttagat gtcaaactaa gcaactttcc tccctactct gactttaaaa tcgcaaatta
    17281 ggtctccaga actattgtat attttgtaaa aaaacagtag aatagaaagg tataattttt
    17341 aaagaaggaa taaaaacagt gaaatctatt aaacgttttg cactctcagc tatgggagcg
    17401 gctatgttgc ttgtcttgac tggttgtgtc aatgtcgata aaaccacagg tcagccaaca
    17461 ggatttattt ggaataccat cggagcccct atggctgaag ctatcaagta cttcgctact
    17521 gataaaggtc taggctttgg tgtcgctatc atcatcgtaa ccattatcgt gcgcttgatt
    17581 atcttgccac ttggtatcta ccaatcatgg aaggcaacgc ttcactctga aaagatgaac
    17641 gccctcaagc acgtccttga gccacaccaa acgcgtctca aagaagcgac tactcaagaa
    17701 gaaaaactcg aagcccaaca agctctcttt gctgctcaaa aagagcacgg tatcagcatg
    17761 tttggcggtg taggatgttt ccctatcctc cttcaaatgc ctttcttctc tgctatctac
    17821 tttgctgccc aacatactga aggggttgct caagcaagct acctaggcat tcctctaggt
    17881 tctccaagta tgattttggt tgcctgtgct ggtgtccttt actatcttca atcgctcctt
    17941 tcacttcacg gagtagaaga tgaaatgcaa agagaacaaa tcaagaaaat gatttacatg
    18001 agcccactca tgatcgtcgt cttctccctc ttctcaccag ctagtgtcac actttactgg
    18061 gttgtcggtg gtttcatgat gattctccag caatttatcg tcaactatat cgttcgtcca
    18121 aaacttcgca aaaaagtcca tgaagaactg gcaaagaacc catcaaaagc aagtgctttc
    18181 tcaacaccaa gtggacgaaa agacgttacc cctgaacaac caactgctat tacaagcaag
    18241 aaaaaacaca aaaatcgcaa cgctggaaaa caacgttcga gataagaaga aaaaggctta
    18301 gctgatttgc taagtctttt tgcaagtcaa aagcccgatg tttccatcag gcttcttttc
    18361 tatccatgta cacgtttcat ataatcttga taactttcgg tatccatgag ttttttagcg
    18421 ttcttgacgc gatctgctgt tggtggtttg actccttcga gggaatatgg aattccaagt
    18481 tcacgccact tgaactcacc catggtgtga taaggtagaa tttcaaactt atcaacattt
    18541 ttgagggtct tgacgaactt accaagttca atcaagtcat catctctgtc tgtcaatcct
    18601 ggaactagca cgtggcgaat ccagacaggt tttccaatat ctgatagata ctgggcacaa
    18661 gccaagatat ttttattggt ttggctagtg acaatcttgt gctgttcttc gttgatttcc
    18721 ttgatatcca aaagaaccaa gtcagtgaca gccatgagtt tgtcaaactt ctcaaggtaa
    18781 cgcggtttat tacggaaagg aagagcacag gtgtccaagg tacagtggat tccttgttcc
    18841 ttagccttgg tgaagagagc aatcaggaaa tcaatctgca agagagcttc tcctccactg
    18901 actgtaatcc cacccttatt tccccagaaa ccacggtagc gcaaggcctc tgtcaagaca
    18961 tcatctaccg tccgttcacg tgacttattg gactccatag cccaagtgtc tgggttgtgg
    19021 caatactggc aacgcatgtg acagccctgc aaaaagacaa taaagcgaat accaggccca
    19081 tctactgacc caaagctttc tgtcgaatgc accatccctg tcacttgtcc ataatcaatt
    19141 gtttcttcag acatatcgtt accttccttg aaaacgtttt atagttttat tatatcacga
    19201 cttgaaggaa aaacaagatt tttgcctatt ttttagaaag caatctgttt ttcaatttca
    19261 ttttcaatct attatcagat tattcttcaa aatcgaagcc atataaggtt gcaaaatagt
    19321 cctcagggcg ctctgcacgg cggatttgac gggctttacc ttcttcggta tagaggattt
    19381 ccgcagaacg taatttggca ttatactggt agcccattga aaatccgtgg gcacctgtat
    19441 catgaattac cagcaaatca ccgatttctg tatgaggcag ttcgcgattg actgcaaatt
    19501 tatcattgtt ttcacagagt gaaccaacca catctaccgc ttcagctggt ccatctggat
    19561 gggtcacgtt gctaatatga tggtaagctc cgtacatagc tggacgcatg aggttgactg
    19621 ctgaggcatc tacacctaga taggtacggt aggtttcctt cttatgagtg actcttgtga
    19681 ctagagcacc gtgaggtgcc agcataaaac gacccaattc ggtgaaaatc ttgacctgac
    19741 caagacctgc tgacgtaaga acttcttcat acaccttacg aactccctca ccaatcaagg
    19801 cgatatcgtt cggctcctgg tctggacgat aattaacacc aataccgcca gaaagattga
    19861 taaagtctaa cgaaatgccc aacttttcct tgatttcaac agccagttca aagagctgac
    19921 gagccaactc tggataatag agatgggtca cggtattgga cgctaggaag gagtgaagcc
    19981 caaaagtctt ggctcctttt tccttcaaga tagcaaaggc ttcaaagagc tggtccttgg
    20041 tcatgccaaa cttagcctcc ccaggattgt ccataatgtc tgtccccagt tcaaaaacgc
    20101 ctccaggatt ataacgacaa gagatgattt ctggaatgcc tgctactctc tccagatgtt
    20161 caatatcttc aaaggcatcc aagttaatgg tcgcacccaa ttcacgtgca taggcgtatt
    20221 ccttgtctgg cgtgttgttg gaagagaaca taatctcaga acccagaaag tccagtttat
    20281 ggctcatcaa aagctctaca taactagagc agtccacacc acaaccttct tcttggagaa
    20341 ttttcaaaat agctggagtt ggagtagcct taactgcaaa atattcctta aagcccttgt
    20401 tccacgaaaa agcttggttg acagctcttg ccttctcacg aatccccttc tcatcataca
    20461 agtgaaaggg agtcgggaac tcggcaacaa tcgcttctaa ctcttctcta ttgataaatg
    20521 gtgttttcat aagcttcctt ctattctgtt tgcaaagaaa ggctgggaca atcgttccaa
    20581 cctttagttc tatctcttat ttatcttcgt caaagatatt gccaacctca acatcgatgg
    20641 cttggttctt gacatcaata ttggttacct tcaagagtga cttgtagtca aactgctttt
    20701 cacgttcttc ttgggcattg tccgcaaaga ccgctacacc tgccagttct gagtcgaact
    20761 cgcgcaagag actaatcata ccgttgaccg ttccgccacc tttcaagaag tcatccacaa
    20821 tcaagacacg gctgcctgcc ttaagactac gttttgaaag gaacattttc tcgatacggt
    20881 caccacttga acctgaaaca tagttgacgc taacagttga accttcggta attttcaggt
    20941 cacggcgcac aatgacaaaa gagacattga ggacattggc aactgcattt gcaagtggca
    21001 cacccttagt tgctacggtc ataaccgcgt caattttttg gtccataaag cttttggcaa
    21061 taatacgacc aatatttttc aagatggctg gtgtgctaag caaatcagac agatagatat
    21121 aaccacctgg caagatacgg tcactttctg acaacttggt acgcaagtct tcaaccattt
    21181 ccttagcatc ctgactcgaa atagacggtg tgaagatgac acctccgcca gccccagtca
    21241 ctgtctggat atgaccgatt tcaatttcct caaaggcgcg tttgataatg acgatatctt
    21301 ctgagatgga tgatttagca gactcatact tttcagcaaa agtattgaga ctagttagtt
    21361 tataaggatt attaatcaaa tagttggaaa tgacaaccat ccgatcactt cttcttaatt
    21421 tcatttctat ttcctattcc atttttattc aaaaaatcaa aaagcaaact agaaagctgg
    21481 tcgctggtgg ttcaaaacac tgctttgaga ttgtcgatag aactgacaaa ccctgtaata
    21541 tacctgcata tatacatacg acaaggcgat actaccctag tttgaagaga ttttcgaaga
    21601 gtattcattt ttgtctttta cttattatac catattcaca taaaaaaacg aacattctta
    21661 tcctaaaaaa tgctcatttt tcttaaatta ttaatctaaa tctggtttat agaaggaacg
    21721 attatccata gcgaagattt tattggacat ctctccttta tccaccaaag ccagagctgt
    21781 tgacatcatc atcatgcttg catccagatt gtcaatcata tggataatct ctgcctccat
    21841 aatacgtgga cggactggac ttccatattc aagcaagccg tggtgactga ggatgacatg
    21901 acgaagcaaa acgacttctt ccttggtatc gtcgatgccg agttccataa ctgtcttggt
    21961 aatttcgcta tcaatgagag cgatatgtcc aagaagattg cctcgcactg tgtactctgt
    22021 ctggtctggc cccgtcaact cgatgacctt agctaagtca tgcaacataa tccccgcata
    22081 gagcaggctc ttattgagct gaggataaac ttcgctaata gcgtctgcca aacgcaccat
    22141 ggtcgccgta tgataggcca agcccgtttc aaaggcatgg tggttggtct tggcagctgg
    22201 ataggagtag aattccttat catacttggt gtagagattt cggacaatcc gttgccagac
    22261 aggattttca attttgaaaa tcatttgcga catgtagtca cgaatttcct tgacatcaac
    22321 tggtgacttg accttgaaat cagctgggtc attgggttca ccagcttgag gcaggcggag
    22381 agtaatttga ttgacttgag gggtattgtt ataaacttct cggcgtcctt tcatgtggac
    22441 aaccttacct gcggtaaagg cctcaatgtt atgaggttgg gcatcccaga gcttcccatc
    22501 aatctcgcca ctatcatctt ggaaggtaaa ggctaggtag tttttcccag ctcgagtttg
    22561 cctcaggtca gctgatttga ttaggtaaaa gccttcaaat aactcatctt ttttcatgtg
    22621 actaatcttc atattcttcc tcattttctt gaaaatggag tagatcaagc gcaggctcac
    22681 cttctgacaa ctcaatgtga cggagcgtcc gctcgatagc tatggtacga cggtttaata
    22741 attcatcaat attgccagag gcatgttgga gatgtttttg tgccttgacc agaataccac
    22801 caaacttgcc aaactcggtc ttgacactgg caagagtctt gctgatatgg tcggcactct
    22861 tttggatatt aagggtcttg aaaccaactg atagggagtt aagaagggct gatagggtac
    22921 ttggtcctgc aacaataatc tgttcttccc gtctcaaatc atcaaagaag accggattgc
    22981 ggacgatttc tgagtagaga ccttctgtcg gaacaaacaa gattccaaaa ttggttgtcc
    23041 gaggcggtgc tatgtacttg ctcttgatat ccttggcaaa gcgcttgacg cttgctagga
    23101 gtgacttacg acagcgttca atctcatcct tgtcacctgt ctcataggct tcttccaagc
    23161 ggtaataatc tgccagtgga aacttagagt caattggaag atagacgtat tcttggtcgc
    23221 cttgtccggg taacttgatg gcatactcca ctcgttcact agagttttca accgttgcgt
    23281 attctcgttc gtactgggca ggtgtcatga tgtcttcaat aatttgcccc agttgcaatt
    23341 ctcccagaat ccctcgcgtc ttggttccag agagaacctt gttaagagct ccgacatcac
    23401 gggcaactgt ctgcatttct ccaagaccac gattgacaga ctccagttgt ttagaaactg
    23461 tctcaaagga agcctgtaag cgtgtctgca aggtcttttc tagtttttcc tcgaccgtct
    23521 ggcgcatttg ttccaaacgt tgctcatttg attcctgcaa ggcttggaga cgttggtctg
    23581 tcttgtctct agtttggagg agattatctg tcatttcttg acggacttgg gtcaggcctt
    23641 ggtgcaattc aatccgcact tcttgcaaac ggtcgctgac agccacttcc aaatcttttt
    23701 ggtctaactg gctggcttgt ctggcttggt caaagcggta atccaactgg tctgacaaat
    23761 gatctgcctg atcctccaag ctcttactta agtgtttctc ctgcctatcc tgcctttgcc
    23821 aaatcagaaa gagaccagct aggttggcaa ttaataatag aataagtaaa ctttccatcc
    23881 tacctcctat ccttgctatg cagtacgacc acataaccat ctgggcaagt taccgacact
    23941 tccctatcta tatattcgtt agaagcgtac acttttttaa agaaaaaatt ttcctctgtc
    24001 aactcatact tggctccaag aatagtcagc tggctatccc gaactggcat aaaggctaga
    24061 tagtcgtagt ctgaacgagg ttctagctga ctggtccctt ctggacaata agtaatcaag
    24121 ttttgcccat cctcaatttc tatttgatgc atatagggtg ccaacttagg attgctaggc
    24181 agaaagacat tggccaacat atggtcaata cggccaccca aggcaccgaa aatagtaacc
    24241 tgagcctgag gattttgttc aaagatggtt aagagagcca attccaaatc ggtatcatct
    24301 ttttctggtc gtgcttggac aaaatgctgg gcacgttttt gaatcacctg tcgctcttct
    24361 tcggtcacag aatcaaaatc cccaactgct agagcaagag gcaagtcttc ttccaagacc
    24421 cagagcgagc ctcgatccac cccaacaaaa gcatcaaaat ctgtccgata atgaccgcgg
    24481 tctccgcctg caaaaacggc aaccctagtc cagttgtttt ctgagagttt gtactcgctc
    24541 attgacatct cccttaaaga cataggaacc tgctacaaaa acggtcgcac cagcttcttt
    24601 agcttgggca atagtttggt catcaatccc accatccact tcgatttcaa agttcaaacc
    24661 tttttcctca cgaagagcaa ccaactcacg aaccttatcc atggtttctg gcagaaaggc
    24721 ttgcccacca aaacctggat taaccgtcat gactaaaact tggtcaacta gatgaaggac
    24781 gtgcttgatg gcttcaactg atgtgccagg attgataacg actgaaggct taactccgag
    24841 tgaacgaatt ttttggaggg cgccatgaat atgaggcgtt gcttctacat ggatactgat
    24901 gatgtctgca cctgcgcgcg caaagtcttc cagatggtgt tcaggattcg ccaccatcaa
    24961 gtgacagtca aagaccatct tactatgtgg acgaagtgct tcaaccacac cggcaccaaa
    25021 actgatttgt ggcacaaaat gactgtccat gatatcgata tgggcatatt ctgccccagt
    25081 tgcttctaga cgtttgattt cacgttcaaa gttggcataa tctgctgcca gaattgacgg
    25141 agcaatcttg tattgagaca taggtttctc cttattttgg aatttttttg ctgacttttt
    25201 tatgggtttc tctacgattt tcaatttcac taaggaattg caggtaattg tcaaaacgga
    25261 aggttgcaat aacaccctct tcaacagctg gtttgacggc acaagacggc tcatgggtat
    25321 gggtacaagt acgaaactta caatctcggc tgacagtagc aatctctggg aaagcctgat
    25381 tgaggtcttc agcccttgat acttcatagt ccagagatga aaagcctggt gtgtctgcga
    25441 ttttaccccc attgaggttg aaaaaactaa cagctcgagt agtatggcgc ccacgaccca
    25501 gactgtctga gatttctcct gtttcaagat tgaggtctgg tgcgattttg ttgagaagag
    25561 ttgacttccc aacacctgtc tgccccataa agaccgtaac cttgcctgtt aacaaagaca
    25621 ggagttcctc tttactggtc acaaagtcat agccgatgtc accataggtc tgctggtaaa
    25681 aatccagttc tcccctatct tccaacaaat ccattttgga aatatagaca atgggatgga
    25741 tgcccttgtg ctccaaaaga accaagaaac gatccagcaa attgctgtta aaatcaggtt
    25801 ccttgacgga catgattact acagcttgat cgatattgac aataggcgga cgaaccagac
    25861 tgtttttccg ttcgtgaatt tttaggatat agccttctga attttcctcg gcagagaaat
    25921 ctacccagtc cccaacataa ggggtatggc cttttttacg gaaattccca cgcgcgcgtg
    25981 tttgataaac ctggccatca ctctccacat agtagaaacc tgccaaggct ttaatgattt
    26041 gtccctgcat cttagagtcc ttgcccttta agtgcgtctg ctagacaggc aaattctgcc
    26101 aagctgagag cttccccacg cacacttggt gacaagcctg cctggtccaa agccttggtc
    26161 agcttgtcct tgacctcttc agtcttacca aagtaacctg tcaagttatt ccacaaggtc
    26221 ttacggcgat gggtaaaact agccttggaa accttaaaga agaagttctc atcttccact
    26281 gctacagctg gctctggacg gcgcaccatt ttcaagatgg ctgaatccac atttggcgct
    26341 ggcacaaaga ccgtacgagg cacgataaag gcaaccttgg ctgtcatgta atactgcacg
    26401 gcgatagaca agctaccgta agccttggtg ttaggctggg ctgaaatgcg gtccgctact
    26461 tctttctgca tcatgaccac aaactcacta aaaggaatcc cactctcaat caagtgcatg
    26521 agaataggcg tcgtgatgta gtaaggcaaa ttagccacta ccttgattgg caggttagga
    26581 tttttaaaat tttggatatg ttgcgccaaa tcaaccttga gaatatcttc gttaactaca
    26641 gtcacattat caaaatcacg cagggtatct gccaaaattg gcaccaaacg gtggtcaatc
    26701 tcaaaagcca tgacttgggc tgcacgctca gccagaaact ccgtcaaggc accaatacct
    26761 ggcccgattt cgatgacatt gacctggtca tcaatttcag ccgtatccac aattttttga
    26821 aggatattgg tatccgtcag gaaattttgc ccgaaggact ttttaaaggt aaaaccgtga
    26881 cgctccagca ctgccttggt cacgctataa tctgcaattc tcatctattc tcttttctat
    26941 tatctgttac tactattgta acacattccc cttgtatttt gggaatgaaa atcataccaa
    27001 aaaactatct ttcctcatga agaaagatag tcttggaaat ctttaaaagt ggccttaaca
    27061 gttctctcga aacatgcgtt caaaaaaatc agcttcttga taacttcgat tttcgggtag
    27121 ggtcaaatcc acatcctcct ccacatcatc cactgtcagt tcaaccgtct gaggtaaatt
    27181 tttcaaacga taatgctttt gcctttgccc ttcaatacta gcaaaatcaa gcaaatagcc
    27241 atgtactcgg atttgaacca aaaggagatg attggtcata ttttccatga tgaggatatc
    27301 ttctaaacca cctctggcac taggataatc agatactctg cgaatacgga ttttttcaca
    27361 catgagcaag tttcctcata tcaatgattt catcagcctt attccagact aggggattat
    27421 gggtcgcaat gatgatcatt cgattttcat ctttcaaatc caccaagaga ttcataacct
    27481 cctctgaatt ttcaggatca agagctgctg ttggttcatc tgccaaaatc aagggtggat
    27541 ttttcaaaat agtcttagca agggcaactc gttgggcctc tcccccagat aaagtataaa
    27601 ttttttgttc taaatccaaa taccctagat taactttttc taaagccccc acttgccttt
    27661 ccaaacgttc tacttttgag attttctgac caacaaaacc caaatccaaa ttttctttga
    27721 ttgattggtt ttctaagagg ccaaaatttt gaaagagata gcccatctga tctcgaaaat
    27781 actcacgagt gggaatggtt tttaaatctt tcccctgata gagaaccctt cctccatcta
    27841 tcttttctag ctttcccaag atattcagca gcgtcgtctt tccgcttcca ctctttccga
    27901 ttaaggcata aaccttgccc ttctccagct tgagattcaa accagagaaa atcgcgcggt
    27961 cattaaattt cttttccaat ccttgaatat caatcatctt attttccttt caatactgcc
    28021 atgctaccag cttcttcttt tttgtcctgc cttactaaaa tcaagagggc gttaagcgta
    28081 aacaaagcta caactagagc gctaatcaaa ccatctcttg tcaaaatact agataggact
    28141 aggccaagca agagaactcc tccttgcgcc agtaaatact tgccatgaag ctcatagatt
    28201 gtcataccag caagacgttt aatcataagc tcccgtctga actgctcaaa atagagaaga
    28261 ttcatggaat caaataacaa gatagccgta gacagggtca aaatcgtccc aataaggaga
    28321 gagtaaaact ccacccgttt gtcatttagt accttggcaa aaaatagctg gctttttacc
    28381 aagtaagaaa ccttgtgata cagaccttgc tcttttagag ctgtgatgct gtctccatat
    28441 cgatctagtt tcaaggcact attagccgta gttccccaca acatccctgc aacaggtctt
    28501 gttccagtcg cttgcggcgt tagaactaca ataatcggat cttttaggta ctggcgtgtt
    28561 gtcttgtacc catcattata gaggaaacgt tcctgtcctg tttctgtaaa agctagcctt
    28621 acctgtggga agtagtgttt ctgactcgtc acttctacac tttcagatga aaagttttgc
    28681 aggtaatctg taaacaatcc ttggtagtag gcagactgct ctcgcaagct ctcaggcaag
    28741 atcagcccaa actctccctc agacaagttt tgcatcttgt ccataaactc tgaagaaacg
    28801 gtaatctttt cttctatcag atagcgtggt gagacataga taacattccc tgacggtgtg
    28861 tagtcactga gacgattacc atctaggtcc acttctgctc catctgagaa attgtcaaca
    28921 ttgctcataa tataaaaaga gtctgtattg gctaaccgtt cttcagtaaa tgtctgccac
    28981 tcacgattat ccttacgcgt tccttcttca tcggcaaatg cactagacca accaaaggat
    29041 agacggtaac ggtctgagta ctggctccat ttattgctag ctctctccat ttcctgcatt
    29101 tcacggtagt ggggtaggag agctgtcgca ctcgatccga ccaccaatac agctaagagt
    29161 tgccccacca tcatcaatgt catcatacgt ttgagaggga gtttcccttt caatagatcc
    29221 accagactat tttcctgtaa accaagtaga tagacgacac ttagtaaggt agaaatccct
    29281 gccaagatca atccataaag tagaagagca atgatgacca gttgcaccgt tgccataaac
    29341 aaggcacctt gataccagag aatccccaat cccaaaatac tggataccag cactgagcag
    29401 ataagctgtc tcacatcttc taacactggt ctgagagcaa ctccaaacaa gctctcacca
    29461 gctattaagc gaatccctgc ctgacgaagg gatttgatcc gataaatcag ggtcagactc
    29521 ataaaggtca gcagaaaaat agctaaactc agtagcacca taggggtggc cgtcaatagt
    29581 aagactatcg aaaatggatc ttctccattc gaaacaaagc cttgatagcc aagttctttc
    29641 aaggtggtct gtaagctcac tccatccaaa cttcctgaca caatcaagta agaccctaat
    29701 aaatcactcg tttctgcact ctccttggag gaaatggtca gaccttctgg aagctctccc
    29761 tcaccataag tggcataggt aaagagtgtt tctccagctt catttggctc aacgattcga
    29821 cgggcgatga gactattatg ctctaccgcc aagtgactca aagcctctgt caccttttcg
    29881 cgactagcta ctggttgatt tatcatcatt cctgtcacat caacagaagg atagttacca
    29941 aataaaatct cttctcgatg gtcaacggaa gttatcacca tataaagcga taccaatacc
    30001 attgaaatca aaataaataa acgtttcatc atttcctcca aaaagttact tggtcactta
    30061 gtgagaaggt gaccacagtc actgcgatgt taagaagctt attaagttct ttctgctagc
    30121 aacatcttca aatatattat atccgttttt tcaagaacta tcaaggacat caatgtcctt
    30181 aaaatctaac tatttcatat tatttttagc ttatatctaa aaaaacagtt ctaaagacga
    30241 actttagaac tgttttgata cgaggacaag gacatttttg tcactgattc actatgttta
    30301 taaatatttt ttgacatcct cttgccattc ctctgtcaat ttctttacta gaaatccatc
    30361 tccaattagc ttcgcaaatg ttttagaaga ctgataaaat gattcagcta aactaaaatc
    30421 tctttctact cttaatgctt gcttccacaa aaacataaat acaagaggtt tcttttgata
    30481 atcttgagtt ttatccataa tttcttgtaa acacgataga taatcattaa aacaatcagt
    30541 tactcctacc ttttcaagac aacacattcc tgaaataaga gtatctctaa ttataaagta
    30601 attctctatt tgagttacct tcttctgttc caaaagaaag agcattagct tttcgatttg
    30661 atttataaat ttggcaagat cttttctaat gagcatttga taaaaaaaca aacgaatcaa
    30721 caacatatca tttgttgaat aaacttcttt ttctatgatc tgagacatat gttcctcaag
    30781 tattaactct gcatattcag gccttctagt tctagaagta tccaaacacg cctgcaatac
    30841 ttcacatgct aattgttctt ctttaggaag attatcaaag tatgttttat aaatctcttc
    30901 caaacacgct tccttcttat cgtactcctc ttctttacca tagattggtt cacgtaaaat
    30961 ctggtatttc aattctaaat aagcagaagg aagagctgaa aaatccggca taaggctata
    31021 aactggaact cctagccggc gagcaatata gtctaacttg ggcaaactcg gttgcgaagc
    31081 tccactttca attcgcgaca gttgacgaac tgtcagttct tgctcatctc cacaaaaatc
    31141 tggacgacta attccttttt ctatccgaat ctctttaatt ttttgaccaa ttaacatcag
    31201 acgcctcctc ttctacctgc ttcgaaaaat actgtgaaac ttaaaaaatt gtaacggtca
    31261 catctttcct actcataaga tttcatagct tcttccactt ctgccaaagt aaccccaaac
    31321 aactctaggc gtttgaggag ttgcttgccg ttagaatagc cgattcggag agtctctccg
    31381 agatattctc tacgcttaca gctgtctgcc cctgctagaa aaccaaggcg aatcaagtcg
    31441 ctacgactaa tgtcaaactg actctcatgt tcaaattgtt ctgtcacctg agctagagcc
    31501 gttttcaggt cttcatagct ggcatgctca attcccagag aacgcccctt ggtcttggac
    31561 ttgggaacag cttcatctcg cttgagaaag gcatgctgaa ctgttggaat gaccatcatg
    31621 atcatgcgcc gaatccgttc cccattaaaa tctgggtctg taaagacaat gactccatga
    31681 cgttggtgca ggcgctgaat ccgctctata tcctgagcat tgatggcaga acctcgagtc
    31741 tcataggtct ccacatcgaa ataacgtttg agattgaccg tatcatcacg cccttcaacc
    31801 acgataactt gagaaatttt ctctttcatt acttgctgtc cagtccaaaa attcgttctg
    31861 catttgcagt cgttgctacc gccagctctt ctgtcgtcat accacgcaag tcagcgataa
    31921 agtcgaccac atagcgagta taggctgttt tattttcacg accacgcttg ggtacaggtg
    31981 ctaagtaagg cgcatctgtt tccaccaaca tcttgtccaa aggtaactct ttagctgctt
    32041 cttggaggtc agttgccttc ttaaaagtca ccactcctga gaaggaaatg gtcataccaa
    32101 gatccacaaa cttctctgcc cactcaagcg tccctgaaaa tgaatgcatg ataccaccac
    32161 gaggaccaac gccctcactc ttgataatct cataggtatc ttccagcgca tcacgggtat
    32221 ggacaacaaa aggcaaatcc aagtccttag atagctgaat ctgacggcga aaaacctgct
    32281 cctgcacctc tttgggcgct gtcatccaat ggtaatctaa gccaatttca cctaaagcca
    32341 caaccttgga atgttttaac ttatccaaca agtaagcctc aacttcctct gtataagtac
    32401 cagcttctgt aggatgccaa ccaatagtcg catagagctg ctcatactca tctaccaact
    32461 ccaaggcatg ctcaatcgtc ggtttatcaa aaccaacaat attcatctgt gtcacaccca
    32521 tctcagcagc caaggcaatt tcttctgcct cacgacctgc aaattcttct acattcaagt
    32581 gtgtatgtgt atcaaaaatc atctcttcta acctcgtttt ctatcttcta ttataccaaa
    32641 aaagaggagg ggcacctaat ttttcggttt cccctcctct cttcaataga gagctattct
    32701 gctatctttt ctatccgata ttgcccatct cctattccac agttagagac agaagagatt
    32761 ggctacattg atagaatatt cctattcagc taaagtatgt gattatcttg ggttctcact
    32821 tttctcaccc atcactagga ttgatgactt ctcaaaatcc cccttataat ctaactttaa
    32881 gtagagaata gaattttcta gctgttctat tttctacgtc tagtctttct tcctagcaaa
    32941 gcaaaaccac ttgttgccac cactagacca agactagcaa gtgctgcact tgatgctgaa
    33001 cctgtgttag gtaattgttt gccagcaggt gactggtagg taacatcttg cattgttcct
    33061 gcagttgctt gcggtgcact tgttgtctta ggagcagcat taggagccac tggtctctta
    33121 ggaactgtaa ccatggcaat ggcttgcact ccaatcgttt ctgcttcctt cacatcttcc
    33181 atagttttcg cattttcaat ctctttgaga gctgcttgtt tttctgcttc cactcttgct
    33241 aaaagttctg ctttttcttt atcagaaagc ggtgcgcctt tgatttcatc ctgcttgtcc
    33301 ttggctgctt tttcaatggc atttttagct gattcttttt cagtagctaa ttgcttagaa
    33361 gcttgtgatt gagctgagtt ttgtgaacct gtgtgagctg atccacccgc ctggctacca
    33421 ccgccttcat tcgcattagc atctgagctt ccagtattgc ctcccttatc tccacctggt
    33481 gtattttcta gcttatactc tggtgtagct tcttgagtta cagattcacc tttcgcagat
    33541 tgttgaactg tatcttttcc tagaatcgtc actactgaac catctgggaa tgtgattgtt
    33601 gctgtaccat ctccagctac attgattgtc gctccgtcta atgctgaacc atttgcttgt
    33661 aaaatagcaa ccttaacttt ttcttcatct gttaaatgag ttatatcttt tacatctact
    33721 ctttgagcag gtgctttaac agttgatttt tcagcagtca gtttagtgct atcttgtgct
    33781 tttggatctt gtgctaccaa ttgatttcct ggaattgtaa tagctgaacc atctttaaag
    33841 acgattgttg ctgtaccatc tccacctact tcaactttat agtaaaataa aataataaca
    33901 ggacaaatcg atcaggacag tcaaatcgat ttctaacaat gttttagaaa cagaggtgta
    33961 ctattctagt ttcaatctac tgtaacatcg cttccgaatc cgtttgcatc tactgaactt
    34021 ttttacaaaa ataaaaatca gtagactcga gttcctactg atttttgata gaattcgttt
    34081 ggattatgca gccaaaactt tgcgtccttt acgacgacga gctgccaata cgcgacgacc
    34141 atttttagtt gacatacggt tacggaatcc gtgtttgcgc gcacgacgaa gtttacttgg
    34201 ttgataagta cgtttcacga tgaatacctc ctcatagatt ttgtattcgt ttagccggct
    34261 ataaagtgat cagttactaa acatacttta ctattctatc tgattctttc acttttgtca
    34321 atagctctag gcaaatgttt ccagcttttt cgaatgcaag ccctatctac gatactgttt
    34381 caagaaacga gtcatctttt cttggatttg ggctaactca tcaacacgag gaaggtaaac
    34441 gatacggaag tggtctggtt cctgccagtt aaagcctcga ccatgaacca agagaacctt
    34501 ttcctgcttc aagaaatcaa ggacaaactg ctcatcatca tcgatacggt acatattgcg
    34561 gtcgattttt gggaagatat agagccccgc cttgggttta acggcagaca aacctggaat
    34621 atcttgaatg gcattataga tgaaatttct ttgctcgtag attcgtccac caggaagaag
    34681 caattcatcg actgattggt gaccccccaa ggaagtttgt acgacttgtt gggccaaaac
    34741 gttagagcaa aggcgcatat tggacagcat attgagccct tcgatatagc ccttaacatg
    34801 agtcttaggg ccagacaaga ccatccaacc cacacggaaa cctgctatgc ggtgggattt
    34861 tgacagacca ttcatgctga cacagaagac atctggtgcc aagctcgcca caggcgtatg
    34921 cacatgtccg tccattacca tgcggtcata gatttcatcc gcaaagataa tcaaatcgtt
    34981 ttgacgggca atctcaataa tctccagcaa gagttcctta ggataaaggg ctccagttgg
    35041 gttattggga ttgataagga caattgcctt ggtattggaa gtgatttttg acttgatatc
    35101 gtcaatatct gggtaccatt ccacagcttc atcacagata tagtgaacgg catttcctcc
    35161 agctaggctg acagccgccg tccatagagg atagtctggc attggcacta agacctcatc
    35221 cccattgtcc aaaagcccct gcatggacat gacaatcaac tcactgacac catttccaag
    35281 gtaaatatca tcaatatcta cgtttgggaa tttcttcagc tggcaatact gcatgatggc
    35341 cttacgggct gagaaaatcc ctttggagtc agaatagcct tcactatcac gcgcattcat
    35401 aatcaagtca tgaatgacct cgtctggcgc tgtaaagcca aattctgctg gatttcctgt
    35461 attcagacgt aaaatctttt ctccattcgc tcgcatccgc atggcttctt ccaatacagg
    35521 accacggata tcataagcaa catgctctaa cttactagac ttgttatatt ctttcatctt
    35581 gtttcctcaa ttcatcagga tagtaacatt ataccactag aaagagaatg cgacaagttt
    35641 actgaaatgt gttactagtt tcgtatagaa gaaaaacctt gctaaaggcg aggttaagaa
    35701 cgtagagata gcaggtattt tgcaaagaca catcacatac caaaagataa acctagaaaa
    35761 aagcaagcct agaaaggagt cataaagaag attaaacatg aggaaaagcc cccatatcat
    35821 caagtaatcc caacgcccac ttcgttttgc aactagaaat aagattagat ggtagagtac
    35881 atgaaaaact aaaaatccaa taaaacttgg ataaagaagc ggtaccagac tctctaattg
    35941 acagatcatg atcacttcta ccaagactga aactaggata attccataat aaaggaaatt
    36001 tgatttttga aaagagtttt tcatcattct cccttccttc acttctttcc tgctatcctt
    36061 tcttttattt tatcatatat ttatatagag tttaagccct aatattcttt tgaaaaatac
    36121 tttttttgct ttacttctat agtgaaaagg tttacaatta tagtaagaaa atttcaggag
    36181 gtttcattat ggcacaacgt taccaaaata tcatggtcgc aatcgatggt tctaaggaag
    36241 cggacttggc ttttgtcaag ggagttcatt ctgctctacg aaacgacgct aaactcacca
    36301 tcgcacatgt cattgacaca cgcgctctcc aaagcgtatc cacctttgat gctgaagttt
    36361 acgaagaact ccaagtcgac gctgaaagtc tgatgaaaga gtacgaaaaa cgtgctaaag
    36421 atgctggggt agcagatgtt catatcgtca ttgaaatggg aaatccaaag accctgctag
    36481 cacgtactat tccagatgcc gaggaagtgg acctcatcct cgttggcgca actggtctca
    36541 acgcctttga acgcctcttg gtcggctctt catctgaata catactccgc catgctaagg
    36601 tcgatttgct ggttgtgaga gaacaagaaa aaaccttata atcacaaaga aaaggagccc
    36661 ctagctcctt tttgtttacg atttatttct ctctttatgg cgttcgtaag ccttgagctg
    36721 gcgctgcagt tcctttttaa tagcaggttc tggagcatat ttttcttccc aattatctgg
    36781 ttttaagatt ttatgggtca ctggatcaaa atgagccttg ccatctggaa aaattttccc
    36841 catattggcc tgatggacaa tatcaaaaat acgttctggg tccaccccca tcaagacaaa
    36901 actgccgtag gtgaagtaaa gcgtgtcaat caaggcatcc acttgcccta tcaaatcttg
    36961 ctgagcaggt gtcttcttgg ctactttacc tgctgcctta tcaagggcct gatgaagttg
    37021 cgatacagct tgaccaaaat cttcttcaga aggactggct gatcgaacaa actccaccaa
    37081 ttcttctatt ttaaaaccag ccctatgggt tgcaccctct aaatcccaag ctcgaggttc
    37141 ttcttgggtt cgttcatcca tcatgtggtg gaaggtcttg accttattga aatgatagtc
    37201 acagctgaca aaaacttttt ctgaagacaa aacaccaaaa tgttccaagg ccttgtggat
    37261 cccatcttgt tgattgctag tggtaatgtg cttggcagct tccttgacac tgctactacc
    37321 atttcccata gcgaccgaca taccgacgcc agccagcatt tcaaggtcat tatctgagtc
    37381 accaaaagcc atgacttggt tgaggtcaaa gccatattct ttcccaactc ggcgaatgcc
    37441 ttctaattta gaatttccct gattgatgac atccgatgca aaaggattgc tacgtgtcaa
    37501 tttcaagtct tcaaaatcag ctgccgcctt ctcagattct tctggtgtca tcagcatcaa
    37561 aacttggtaa ataggttgat tcatcaggtg aagcaggtcc tcttcctttt ggggaacaac
    37621 cttgctgacc atgcgattaa aagactgact caccgtccga gttaaaacag agggaacgaa
    37681 gcgactaatt cgttgggaaa aagaacccag accaaaggac atgattttag aacccaacat
    37741 ggcatccttg gtccctaagg caatctccgt gccctctttt ttagcatagc taattagatg
    37801 gcgcaaatgt aacttggaaa tagggctcgt gaacaagact ctgtctttac taaagatata
    37861 ctggccatta taggttaccg caaaatccag atccaaatcg tccatcaatt ccttaacaaa
    37921 aaaaggtcct cgccctgtcg ctacgccaac tagtacccct tgttctttga caatcttaat
    37981 cgcgtcctta gtggatttca aaacactctt gcgattgttg accaaggttc catcgatatc
    38041 aaaaaaaaca gctttgactt ccatcctatc ccaatctccc cttttgtgat acaatgatta
    38101 taccacattt cagaaagagt gagtaaatca tgcctaagaa aatccttgtt ttacatacgg
    38161 gtggaactat ttccatgcag gccgatgctt ctggcgctgt tgtgacgagt tcagataatc
    38221 ccatgaacca tgtgtccaac ccacttgaag gaatccaagt ccacgccttg gactttttta
    38281 accttccaag tccccatatc aaacccaaac atatgctggt cctctaccag aaaattaaag
    38341 aggaagcaga taactacgat ggagtggtga tcacacacgg aaccgatact ttagaggaaa
    38401 cagcctattt ccttgatacc atggaagttc cccatatgcc tatcgttcta acaggagcca
    38461 tgcgtagctc caatgagctc ggtagtgatg gtgtttataa ttacctaagt gctttacgag
    38521 tggccagcga tgacagggct gctgacaaag gagttttggt cgttatgaac gatgaaatcc
    38581 acgctgccaa gtatgtcacc aaaacacata cgactaatgt cagcaccttc cagactccaa
    38641 cacatggccc cctcggtctc atcatgaaac aggaaatcct ctacttcaaa acagctgaac
    38701 ctcgtgttcg ctttgacctt gatcacatac aaggtttagt ccctatcatc tcggcttatg
    38761 ctggtatgac agatgagctg attgatatgc tggatttaga acacttggac ggtttgatta
    38821 tccaagcctt cggagctggt aatattccca aagaaacggc tcaaaaatta gaaagccttc
    38881 tgcaaaaagg aattccagtc gctctggtat cacgatgctt taacggtatt gccgagcctg
    38941 tttatgccta ccagggtggg ggcgtacagt tgcaaaaagc aggcgttttc tttgttaaag
    39001 aactcaacgc ccaaaaagct cgcttgaaac tcctcatcgc cctcaatgcc ggactaacag
    39061 gacaggcttt gaaaaactat atggaaggct aatactcttc gaaaatctct gcaaaccacg
    39121 tcacgtcgcc ttaccgtatg tatggttact gacttcgtca gtttcatcta caacctcaaa
    39181 aacatgtttt gagctgactt cgtcagttct atctacaacc tcaaaacagt gtgttgcgca
    39241 gcctttaacc agtcgcctag tccgctctat ggtattcatt aagtcaacat ctcttgttta
    39301 agagcacaaa atcaggaaat cttctcgatt ccctgatttt ttctatttac gttttcgtgt
    39361 tgagctacgt tctgtcaaac catgaggtaa gagaacttca cgttcttcca actcttcctt
    39421 atgcataatc ttggtcaaca tacgcatact aatggcacca agatcataaa gaggttgggc
    39481 aatcgttgtc aagtttggac gggtaaagcg tgagatttgt gaatcatcac tagtaataat
    39541 ttcaaaatct tctggcacag aaacaccctt atcagccaaa ccgttcaaga ctcctgctgc
    39601 caactcatca cctgtcacaa ctgctgcagt tgcatttgat gaaatcaaac gctctgctaa
    39661 ggcgtaacca tcatcatagc tatatttaga ttcaaatacc aaaccctcac tataagtgat
    39721 tcctgctttt ttcaaggttt ccttgtagcc aactaaacga accttaccat tgatgtcatc
    39781 cactagcgga ccgctaacga aagcaatacg ctcattttct ttagcaaggt aactcactgc
    39841 atcaattgtt gcttgcttat agtcaatatt gacacttggc aactggtgct caacatcgac
    39901 agttcctgcg agaacaatcg gagtacgtga acgcgaaaat tctgagcgaa ttttatctgt
    39961 caagtgataa cccatataga taatgccatc tacctgcttt gaaaagaggg tattgacaac
    40021 agaaacttct ttctcgttat cttcatcgct attagctagg acaatattgt acttgtacat
    40081 ttctgcaata tcatcaatcc ccttagccaa actcgaaaaa taaccattgg taatatttgg
    40141 aatcacgaca ccgacagtgg ttgtcttttt acttgcaaga ccacgcgcaa ctgcatttgg
    40201 acgataatcc aaacgatcaa ttacctctag cactttttta cgggtattct cttttacatt
    40261 tttattgcca ttgaccacac ggctgaccgt cgccatggaa acacctgctt cacgagcgac
    40321 atcataaatg gttactgtat catctgcatt cattcctttt cctgtccttt ctatctcaca
    40381 cattctttta caagtagagg tactgattga agctctatat ctacttacaa aagtgaagat
    40441 gtgaaaattt cgttttcata tttctactta ttccattcta tcactaattg taaacacttt
    40501 caagtgtttt ttgaagattg attgaaaaaa tttcatagaa aacctaggtt tagctccttg
    40561 ctaccacctt agactaaaca caaaggagga aactaagccc tcctaaagtt atagtaaaat
    40621 gaaataagaa caggataaat cgatcaggac agtcaaatcg atttctaaca atgttttaga
    40681 agtagaggtg tactattcta gtttcaatct actataggta ttgttccatt cactaccgtc
    40741 aattttagca catagccttc ataaaaatat tatatcatca taaccaacca gattcttttg
    40801 cgatattagc tgcctctgtt cgattaccag catccagttt tgaaagaata ttggtgacat
    40861 agtttcgaat agttccgttt gagaggtaaa gctgatctgc gatttcttgg ttggataagc
    40921 cccgggcgat tccctttaag acagcaatct cttgttctgt caacggattg ggacgggtca
    40981 tcaccacttc catcaattca ggcgaatact ccttgcgtcc ttcgaggacg gtgtgcaagg
    41041 tttgcatgag gtctgcaatg cttcgttcct ttaatacata agcatccact ccagccttga
    41101 ccgcacgttc aaaataccca gcacgcttga aggtcgtcac cacaaccacc tttgtttcaa
    41161 gcctttctga tcgtatccac tccaagactt caagacctgt cttaacaggc atttctacgt
    41221 caaggatggc gatatctaca gactcctttt ctaatagttg gattgcttct tgcccattct
    41281 tggcttgaag gacagactcc acatctggtt gaagcgtgag caattgacac atggcatctc
    41341 gcaacatact ttgatcttct gcgactaata ctttcatctt agtttctctc cttataaggt
    41401 agtcgaactt gcacttccgt tggatgtttc tgactgatta cacttacttc tcctgaaaat
    41461 ggaaaaacac gatctcggac tgtatggagc tcatctcctt ttagaaaagc aaagccgcag
    41521 ccatcatcac ttactgttaa aatgagttcc ttctctgtcc gttctaattt taagtaagct
    41581 ttagacgctt tggcatgttt gatgatattg gtcaccaact caagcaaaat catagaagtc
    41641 attgcctcca attcttgagt aaggctagca gtatctagtt ggttatccgt ttccacctca
    41701 attccagcaa tttctaacat ctttttcaca gtctctagtt cggatgtcaa agttctagac
    41761 ttaagatttt ccacaatggt tcgaacttca cgcatcgatt ctttgctaat ttgctgtatt
    41821 tctcttaatt ccttttccac ttgtggataa gcctgcattt gaaatagctg caaggctaga
    41881 tctgtcttga cactaagcat agcaaaggta tgtcccagac tatcatgcaa atcctgaccg
    41941 atacgattgc gctcattttc tgctagcaat agatttatct gggtattttg ctcgacctga
    42001 gcttctttca aatcctcgac aaggcgaatt cgaaccgagc ccaaagtcat caaatcgaca
    42061 aaagtaagaa ttacaagcat atagactaga aactcaactt cgattctctg aaaaatcaaa
    42121 agtcgcccca caacaaggac ttgagcaagg agaaatgtcc atacatgtaa agactttaaa
    42181 ctacgtacgc caaaatgata aattaagaga ttggaaagga aaaagaaaaa ccagatataa
    42241 ttcccagcaa caaaggcggt attcccagct acatagacca gcatgatccc ccagaaaagc
    42301 caagataggc gctggttctt agttattaaa acacccaaat acgtcactac aaatagaata
    42361 tcaaccaata aatgccaagc aggaagctcc ccaatcacta caggtaggat gggaaaaagc
    42421 ataaaaatca aactgaccca aaacatatag tgtatgcttt tcagtctttc aagcattaag
    42481 cattctcctt atgaccttga aggtaaatag tcaaaccaaa taaaactgct gaaaaaacaa
    42541 gtaaataaac tgtggctgat agattgatgc caccctcgtt taagaaggtc ttgagcaact
    42601 ccatcaattg ataggtcggg agacacttac caactgcttg catccagtct ggaaataaag
    42661 aaatgggcat ccagagtccg cctaaaacag ccaatcctag ataaagaaga ttgcccacaa
    42721 cagacatcag ctgactagtt ggtaagagag tcaaggtcaa gccaagtgct acaaaagcaa
    42781 tactccccac aatcagcaaa atcgcagctc caacccattt tactagaggc atgtctacac
    42841 ctcttacaaa atgtccaact gtaaaaacaa ccagaattga gaccaaataa tcaaccagca
    42901 tacttgttat ctttgataga taatattcta ccatatttac agggctatga cgcaatgttt
    42961 tctgccagtt gttcatctta tcggtatgta aaacagctgg aaatgagagg atagttgtcg
    43021 acatcatgga aaaggcagtc atggagatga ggtaatcacg cataaaattc gcgggttcac
    43081 ctggtgtgtc ctgatagata ccagaaaaaa ataaatagaa agccgtcggc atccctaccg
    43141 acaatagata atagattaat tgtcgtttgg tcaataaaaa ttctatctta ctaagtgcta
    43201 tccatcgttt catcttagtt atctcccttc tgcgtctctt caaagattgt attcaacaaa
    43261 ctacgattat taacttcgat ttcttgcatc ctacatcctg cttgggctaa tagttcccag
    43321 aaagcatctg cttctcgagt gactacttgt aaagaatctt gctttagggt ccagttttca
    43381 accaaatttg actgctctac gacttccttg taagctatag gaaggataaa gtgcttttct
    43441 atttcctcgc tacgcatagc tagaggcgtc gtatctcgaa tcaactctcc cttatttaag
    43501 agcaaaatgc ggtctgcagt gtgttccact tcctcaatat aatgggacga atagagaatg
    43561 gtgactcctt gcgcttttaa ctcctggaca atttcccaaa aacgttgacg agttgaggta
    43621 tccatggacg cagtaggctc atctaaaaaa acaatctttg gtcgcccaat taaggtcaag
    43681 atgaaagaaa agagacgctt ttgaccgcct gataattttt ctgccaactg ttctttttgt
    43741 tgcttgacaa actgcaatag ttgatcaatt tcctgattgc tcaaaggatt tggatagata
    43801 cgttgaaaga aagcaatcaa ctctttaact tttaatttct gaacgattac attttcttga
    43861 gggaggtaag ccctagtata gtctaactta gaactcgtca ctggtaaacc ttgaatagat
    43921 acttgaccgc ttgtgaccag tttatctcca agcaaacaat ctaagagtgt tgtctttccg
    43981 gcaccatttg gaccaattaa ggcaacacat tcaccatcgt tgatttcaaa ggagatgttc
    44041 cgcaaaattt ccttgtcttt tattttctta ctcaatttct caactttaac caccgtcatg
    44101 agactctcct ttcaaccact ccattcccat agggaaaacg acgaaaatca taaatccaaa
    44161 ccccaaagca ccatgaatga attggcgaag caaggcttga tcaaaccaat cagtaaacat
    44221 ttccactaac cataccaaga gtgacaggcc gataaagaaa tagatgatcc ctctcttcat
    44281 tcctcaaact cctttttcac atctctgact aatttcaaac cttctctaac aagccaagac
    44341 atgattccaa agccagcaaa gaccttccaa ggaaaatggt agaaatcctc atccaatccc
    44401 gaaaacatga gataggtcat aactcctgct actactaaac tcattgcaat aatcatttta
    44461 tttctcatct cttcttcccc catttcatac tacaattata gtcttttaaa atcagaggag
    44521 gcagaagctt ctgtcactag aaaatatgac aaatgtcata aaaaattctg ttcaaaacaa
    44581 gcaagataca ctatacaata aaacacaatc agaaaaatct aaggcaactt cctcaaaaga
    44641 gatatcaaac tcaattcaca ccataatgta aactaatact tatttaaaat caaaaagagt
    44701 agaaattttt atcagacaaa cacatatata gtgtattgaa tctataacag taggccttaa
    44761 atactaaaat atttctataa attaatttaa ctttcctgat agaactgttc atatcttatt
    44821 tcaattctct atattatacg ttgaacaaaa cccttctatt gctttcttaa aaatttataa
    44881 gagttataaa atctgttaaa tttcaatgtg tatacctaaa ctacggtatt tattgaaaag
    44941 actggggaca aaaagtatac gctgccaaaa tgaattactg aaaatcaaaa aagagaggac
    45001 caaactgatt ccctcttaat gtatataata tctagtttta aaaatacaca ctcacatatc
    45061 tctgt
//
LOCUS       DAVKMJ010000017        44520 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000017 DAVKMJ010000000
VERSION     DAVKMJ010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44520
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.017"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..213
                     /locus_tag="VW348_000912"
     CDS             <1..213
                     /locus_tag="VW348_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEU9745837.1"
                     /translation="IKIVEILAKNAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKY
                     NISMTDKDLDTFVESAVKQMNDAWKG"
     gene            219..1175
                     /gene="lytA"
                     /locus_tag="VW348_000913"
     CDS             219..1175
                     /gene="lytA"
                     /locus_tag="VW348_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEU9745838.1"
                     /translation="MDIDTSRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHYR
                     KDPELGFFSHVVGNGRVMQVGPVNNGSWDVGGGWNTESYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLAD
                     RWKKYTDGNWYWFDNSGEMATGWKKIAEKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPDFTVEPDGLITVK"
     gene            1407..1649
                     /locus_tag="VW348_000914"
     CDS             1407..1649
                     /locus_tag="VW348_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745839.1"
                     /translation="MKILNIKLANVEQTDSGFEHWVDVTYNVPILKNEYTVRLLLLFG
                     FEIEDPEVIEYLVNAWKYRELVLHSVRMYDMEREAS"
     gene            1627..2010
                     /locus_tag="VW348_000915"
                     /pseudo
     CDS             1627..2010
                     /locus_tag="VW348_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
     gene            2012..2829
                     /locus_tag="VW348_000916"
                     /pseudo
     CDS             2012..2829
                     /locus_tag="VW348_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
     gene            2831..3616
                     /locus_tag="VW348_000917"
     CDS             2831..3616
                     /locus_tag="VW348_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9745840.1"
                     /translation="MKKYQRMHLIFIRQYLKQIMEYKADFLVGVVGVFLTQGLNMLFL
                     NILFQHIPLLDGWSFHQVAFIYGFSLIPKGIDHLFFDNLWALGQHLIRKGEFDKYLTR
                     PISPLFHILVETFQIDALGELLVGVLLLLMTITSLTWTWAKVFLFLISIPFATLIYTS
                     LKIVTASIAFWTKQSGAIIYIFYMFNDFAKYPIAIYHSFLRWLISFIIPFAFTAYYPA
                     SYFLKDKDGLFNIGGLILISLIFFTLSLKLWNKGLDAYESAGS"
     gene            complement(3995..5190)
                     /locus_tag="VW348_000918"
                     /pseudo
     CDS             complement(3995..5190)
                     /locus_tag="VW348_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713014.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            5692..5895
                     /locus_tag="VW348_000919"
     CDS             5692..5895
                     /locus_tag="VW348_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9745841.1"
                     /translation="MYIRLKNLREDKDLSQCQIAQYLHCSQSAYSRIESGKQDIPTSF
                     LKQLAKLYQVTTDYILEMDKFSC"
     gene            6026..6178
                     /locus_tag="VW348_000920"
     CDS             6026..6178
                     /locus_tag="VW348_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745842.1"
                     /translation="MTTNKDNDTSERSGCQRKRTAGEMPMNDLTSHTHGGNYTCYKEE
                     KVWNNQ"
     gene            6345..8138
                     /locus_tag="VW348_000921"
     CDS             6345..8138
                     /locus_tag="VW348_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU9745843.1"
                     /translation="MKKNNVEIIKADSLVRRRGDNVERHLKRVAAYCRVSSDSEDQKN
                     SYDSQVRHYKEYISQRSDWELADIYADEGISGTQVGKRQDFQRLINDCANGEIDYIVT
                     KAIARFARNTLDTLKYVRMLKDMQIGVYFEEENIDTLTMDGELLLTILSSVAQQEVEN
                     TSAHVKKGLKMKMQRGELVGFQGCLGYDYDVETKQISINKKEAKIVRYIFERYLEGIG
                     GKVIARELDELGYKSPRGLEHWNDTTVLGIIKNEKYKGDILMGKTFTVDPISKRRLSN
                     FGEEDKYYIKDNHEPIISKEDFEKAQEIRLRRAGNKKTAANVNGKRERYSKMYAFSSM
                     LECGFCGSILSRRSWHCRSDYRKVVWHCVTSIKKGKKFCKHSKGLEEIAIEGAFLEAY
                     RQVYHSNENLMTDLLETIESELNDNSLNKELKRITNKLRILLKKEENLVNLRLEGKVS
                     DSIYNEKYNEISSEKEFLAEEKVNIETTLKSEIDVKKRLTEFKHLLSSQKMLTEFDRA
                     VFESIVEKIIVGGVNSNGEIDPAMLTIIFKTGEIQNKDGKQFKSKRKNAKLETDKLCP
                     QNSDEDKKLYSQGTDNTRGVCSVAGSILASQ"
     gene            8243..8830
                     /locus_tag="VW348_000922"
     CDS             8243..8830
                     /locus_tag="VW348_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
                     /protein_id="HEU9745844.1"
                     /translation="MGGNPPIKKYSIVDKIVLSTKIKRIIIFTVFRENWEPYMKKYTE
                     VFQSQFPNLNIDYLLLDTEQIDLDSYLDADIIIIGGGNTEKYIATYINQEFKSYIDHM
                     LNKEAKIIGFSAGPLLLGEKVYVSPNDNSDHQIKIKNGLGLFSQFLISVHYDSWNDKA
                     NKDRAEELDNVPIIPLNDHSCLVLDKLGNIIEKID"
     gene            9112..9360
                     /locus_tag="VW348_000923"
     CDS             9112..9360
                     /locus_tag="VW348_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
                     /protein_id="HEU9745845.1"
                     /translation="MCKPISIELCDDEVHSLHEWIDGRDAIDSILTYSENQQYTYGVE
                     AGKILRKIHTIPATEVCEDWEIFFNLKIDDKISNEMIW"
     gene            9536..9789
                     /locus_tag="VW348_000924"
                     /pseudo
     CDS             9536..9789
                     /locus_tag="VW348_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9917..11146
                     /locus_tag="VW348_000925"
     CDS             9917..11146
                     /locus_tag="VW348_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU9745846.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGITIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLMMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            11166..13862
                     /gene="ppc"
                     /locus_tag="VW348_000926"
     CDS             11166..13862
                     /gene="ppc"
                     /locus_tag="VW348_000926"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEU9745847.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    13945..14162
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            14275..15279
                     /locus_tag="VW348_000927"
     CDS             14275..15279
                     /locus_tag="VW348_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9745848.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPEFVLKEAGQVIE
                     "
     gene            15348..16214
                     /locus_tag="VW348_000928"
     CDS             15348..16214
                     /locus_tag="VW348_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9745849.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGHMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            16211..16969
                     /locus_tag="VW348_000929"
     CDS             16211..16969
                     /locus_tag="VW348_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9745850.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFEQDFITILGGN
                     GAGKSTLFNTIAGTISLTSGTIRILGEDVTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLFPRRLASYKDKFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRVIQDLKQEEKAKMKISDYYQLFE"
     gene            17059..18819
                     /gene="dnaG"
                     /locus_tag="VW348_000930"
     CDS             17059..18819
                     /gene="dnaG"
                     /locus_tag="VW348_000930"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEU9745851.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPYQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRVGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VKEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            18822..19931
                     /gene="rpoD"
                     /locus_tag="VW348_000931"
     CDS             18822..19931
                     /gene="rpoD"
                     /locus_tag="VW348_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEU9745852.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            19945..20274
                     /locus_tag="VW348_000932"
     CDS             19945..20274
                     /locus_tag="VW348_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEU9745853.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            20389..21432
                     /gene="cpoA"
                     /locus_tag="VW348_000933"
     CDS             20389..21432
                     /gene="cpoA"
                     /locus_tag="VW348_000933"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEU9745854.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAALKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            21448..22773
                     /locus_tag="VW348_000934"
     CDS             21448..22773
                     /locus_tag="VW348_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEU9745855.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLVAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            22804..22980
                     /locus_tag="VW348_000935"
     CDS             22804..22980
                     /locus_tag="VW348_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU9745856.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIVPVATDY"
     gene            23039..23173
                     /locus_tag="VW348_000936"
     CDS             23039..23173
                     /locus_tag="VW348_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEU9745857.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            23237..24547
                     /gene="obgE"
                     /locus_tag="VW348_000937"
     CDS             23237..24547
                     /gene="obgE"
                     /locus_tag="VW348_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEU9745858.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            24557..24715
                     /locus_tag="VW348_000938"
     CDS             24557..24715
                     /locus_tag="VW348_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745859.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            complement(24767..26093)
                     /locus_tag="VW348_000939"
                     /pseudo
     CDS             complement(24767..26093)
                     /locus_tag="VW348_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            27196..28455
                     /locus_tag="VW348_000940"
     CDS             27196..28455
                     /locus_tag="VW348_000940"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEU9745860.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            28471..29022
                     /locus_tag="VW348_000941"
     CDS             28471..29022
                     /locus_tag="VW348_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9745861.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            29015..30292
                     /locus_tag="VW348_000942"
     CDS             29015..30292
                     /locus_tag="VW348_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEU9745862.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            30308..31168
                     /locus_tag="VW348_000943"
     CDS             30308..31168
                     /locus_tag="VW348_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEU9745863.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVIGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            31391..31501
                     /locus_tag="VW348_000944"
                     /pseudo
     CDS             31391..31501
                     /locus_tag="VW348_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818216.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase"
     gene            31547..32351
                     /locus_tag="VW348_000945"
     CDS             join(31547..31915,31917..32351)
                     /locus_tag="VW348_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEU9745864.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADFGIHESNLLRRSQWVEVTLVQSGFTISR
                     TPLSSEDTVMIDATEVKINRPKKELANDSGKKKCHAMKAQAIVTSQGRIVSLDIAVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTVEDKAYNHA
                     LSKDRSKVENIFAKVKTFKMISTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            32543..34834
                     /gene="pcrA"
                     /locus_tag="VW348_000946"
     CDS             32543..34834
                     /gene="pcrA"
                     /locus_tag="VW348_000946"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEU9745865.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            34877..35557
                     /gene="radC"
                     /locus_tag="VW348_000947"
     CDS             34877..35557
                     /gene="radC"
                     /locus_tag="VW348_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEU9745866.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(35554..36243)
                     /locus_tag="VW348_000948"
     CDS             complement(35554..36243)
                     /locus_tag="VW348_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEU9745867.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDSGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELTLIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(36261..36902)
                     /locus_tag="VW348_000949"
     CDS             complement(36261..36902)
                     /locus_tag="VW348_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEU9745868.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(36985..37200)
                     /locus_tag="VW348_000950"
     CDS             complement(36985..37200)
                     /locus_tag="VW348_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEU9745869.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(37208..37555)
                     /locus_tag="VW348_000951"
     CDS             complement(37208..37555)
                     /locus_tag="VW348_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEU9745870.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(37560..38675)
                     /locus_tag="VW348_000952"
     CDS             complement(37560..38675)
                     /locus_tag="VW348_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU9745871.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(38685..39644)
                     /locus_tag="VW348_000953"
     CDS             complement(38685..39644)
                     /locus_tag="VW348_000953"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEU9745872.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGAPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(39757..40326)
                     /locus_tag="VW348_000954"
     CDS             complement(39757..40326)
                     /locus_tag="VW348_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEU9745873.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            40454..41125
                     /locus_tag="VW348_000955"
     CDS             40454..41125
                     /locus_tag="VW348_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEU9745874.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            41109..41927
                     /locus_tag="VW348_000956"
     CDS             41109..41927
                     /locus_tag="VW348_000956"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEU9745875.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            41924..42820
                     /locus_tag="VW348_000957"
     CDS             41924..42820
                     /locus_tag="VW348_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU9745876.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEEGFETLEAIEHLLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            42864..43838
                     /gene="pta"
                     /locus_tag="VW348_000958"
     CDS             42864..43838
                     /gene="pta"
                     /locus_tag="VW348_000958"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEU9745877.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(44099..>44520)
                     /locus_tag="VW348_000959"
     CDS             complement(44099..>44520)
                     /locus_tag="VW348_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9745878.1"
                     /translation="SDKRFYRPTFRMHLTNKEILDKLLSYSQDLKHHYQLYQLLLFHF
                     QNKDPEKFFGLIEDNLKQVHPLFQTVFKTFLKDKEKIVNALQLPYSNAKLEATNNLIK
                     LIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT        13614 a         7703 c         9714 g        13489 t
ORIGIN      
        1 atcaagattg ttgaaatctt ggctaagaac gcagttaatg ccgttgagca agtagctgct
       61 gaaactggct acaagggaga tgaaaaactg gcacaggctc gcgctaaagt ccgtgctgag
      121 cttacaaaat acaatattag catgactgac aaagacttag acaccttcgt agagtccgca
      181 gtgaaacaga tgaacgacgc ttggaaagga taagagtaat ggatatcgat acaagcagac
      241 tacgtacagg cttgcctcag gtcggtgtgc agccttatcg acaagtacac gcccactcaa
      301 caggcaaccg taactcaaca gctcaaaatg aggctgatta ccactataga aaggaccctg
      361 aactagggtt cttttcacat gttgtcggaa atggccgtgt catgcaagta ggtcctgtga
      421 acaacggaag ttgggatgtt gggggcggtt ggaatactga gagttacgca gcggttgaac
      481 tgattgaaag ccattcaact aaagaagagt tcatgacgga ctaccgcctt tatatcgaac
      541 tcttacgcaa tctagcagat gaagcaggtt tgccgaaaac gcttgataca gggagtttag
      601 ctggaattaa aacgcacgag tattgcacga ataaccaacc aaacaaccac tcagaccatg
      661 tggatccata tccatatctt gcaagttggg gcattagccg tgagcagttt aagcatgata
      721 ttgagaacgg cttgacgatt gaaacaggct ggcagaagaa tgacactggc tactggtacg
      781 tacattcaga cggctcttat ccaaaagata agtttgagaa aatcaacggt acctggtatt
      841 atttcgatgg ctcaggctat atgcttgcag accgctggaa gaagtacaca gacggcaact
      901 ggtactggtt tgacaactca ggcgaaatgg ctacaggctg gaagaaaatt gctgagaagt
      961 ggtactattt caacgaagaa ggtgccatga agacaggctg ggtcaagtac aaggacactt
     1021 ggtactactt agacgctaaa gaaggcgcta tggtatcaaa tgcctttatc cagtccgcag
     1081 acggaacagg ctggtactac ctcaaaccag acggaacact ggcagataag ccagacttca
     1141 cagtagagcc agatggcttg attacagtta aataaataga aaggaaactt tctaaattgt
     1201 tctttcaccg caggctcagg cttgcggttt ttttgtttgt ctgaaaattg acttgttggc
     1261 gtcaacaaat agtattaaat cgcttggttg ccaattttgt tgacattaac aaaattgctc
     1321 tgaaagtact gtctgaatta aaaaagtaat gattttttca taacttttta tcttctttta
     1381 cgaatagata agtaggagga ataaaaatga agattttaaa tattaaacta gcaaatgtag
     1441 agcagacaga ttcaggcttt gagcattggg tggatgtgac ttacaacgtc ccaattttga
     1501 aaaacgaata cacggttaga ttgttgctgc tctttggttt tgaaattgaa gatcctgaag
     1561 tgattgaata cctggtcaac gcttggaaat atcgtgagct ggtcttacat tctgtgagga
     1621 tgtatgatat ggagagagaa gcaagttaaa atactgttac taactctaac ttatcttgaa
     1681 cagttatgtg atcgtatttt tatgattgat aagggccgag aaatctttga tggaactgtg
     1741 aatcaactga aaaagacttt cgggaagatg aagactctct cttttgaact acatcctggg
     1801 caggattata ttgtctctca ttttgaagga ctttctgata tctatgtgac gagacaggaa
     1861 ttgtcacttg atattcagta cgacagctcg cagtatcaaa cggctgacat tattcaacaa
     1921 actttgtctg attttacgat ccgtgattta aagatgacgg atgcgaatat tgaagatatt
     1981 attcgtcgct tctatcgaaa ggagctttag gatgactaaa ttatggaaac gctataagcc
     2041 ttttgttagc gctggaatcc aagaattaat cacgtatcgt gtcaattttt ttctttatcg
     2101 cattggggat gtgatggggg cctttgtagc attttacttg tggaaagctg tgtttgattc
     2161 atctcaccag tctctcattc aaggttttac tttatctgat atgaccttat atatcatcat
     2221 gagttttgtg acgaatctac tgacaaaatc agatagttct tttatgattg gatgggaagt
     2281 aaaggatggc tctattatta tgcgactgct tcgtccagtt cattttgcaa tgtcttatct
     2341 tttcacagaa attgggtcta gatggctagt ttttgttagt gttggtctac catttgtaat
     2401 tctgattgca ggtctaaagc tcttatcagg tgagtccttc ttacaaattg ttttaataac
     2461 cacagtttac cttcttagct taatcttagc ttttttgatt aatttttttt caatatttgc
     2521 tttggttttt cagcttttgt gtttaaaaac ttatggggat caaatctttt gaaaaattct
     2581 ttagttgcct ttttatctgg aagtttggtt cctctgacat tttttccaaa aattattgcc
     2641 gaactattat cttttttgcc attttcttct ttaatctata ccccggtgat ggttattata
     2701 gaaaagtata gcatgagtca aatgattcag gcgctctcgc tacaattatt ctggctgttt
     2761 attatgattg ccttatccca actgatttgg aagtgcgtac agaattatat aactattcaa
     2821 ggaggttaga atgaagaaat atcaacgcat gcacctgatt tttatccgac aatatcttaa
     2881 acagattatg gagtataagg ctgatttttt agttggtgtt gtgggtgtct ttttgacaca
     2941 agggttaaac atgctgtttc taaatatttt gtttcaacat attcccttac ttgatggctg
     3001 gagttttcat caggttgctt ttatttatgg tttttctctc attcctaagg gaattgacca
     3061 tctctttttt gataatctgt gggctttagg acaacattta attcgtaaag gagaatttga
     3121 taagtatttg actagaccca ttagcccttt gtttcatatt ttagtagaaa cgtttcaaat
     3181 tgatgctctt ggagaattgt tagtaggcgt cttattgctg ttaatgacaa taactagtct
     3241 tacttggact tgggcaaagg tttttctctt tttaatcagt attccctttg caaccttaat
     3301 ttatacctct ttaaaaattg taacagctag tattgctttt tggactaaac aatctggggc
     3361 aataatttat attttttaca tgtttaatga ttttgcaaaa tacccgattg cgatttacca
     3421 ttcgttttta cgttggttga ttagttttat cattcctttt gcttttacag cctattaccc
     3481 agctagctat ttcttgaaag acaaggatgg attgttcaat attggtggat tgatccttat
     3541 ctcattaata ttttttacct tatcattaaa attatggaac aaaggtttgg atgcatatga
     3601 gagcgcaggg tcttagaaga agtaaaatct aattaagaat tttgatagaa cttcctattc
     3661 tttggaagga agttttaatg atacattgag agctttgatt aggcttactg tagtttttca
     3721 aacaagaaat ttgaccattg tgcaaaaatg atacaaaggt atgtaatatt tcagtcataa
     3781 ccactcgttc atatcatgag tggtttttta gctcttttat acataccatt tgttaaggga
     3841 catacgatat tctagctcaa aaggttttct gaatgagtat caaaggaatg tttagaagat
     3901 aattgcgagc tgttttttga aatttgggca cacttaaaag acacttatct ggtattaaaa
     3961 aataaggtgt tacaatgata ggacatagat gactttaatg actttgggtt aaagtgtagt
     4021 cgtaaagttt gttatgcgtt atgaggtaat acattgtccg gatgaggcga tgtatagaga
     4081 caatcgtata tggcttggtt gaagtcgtct gcgattgtct ttttcgtttc tcataaaagt
     4141 ccgcgatatg acaaggattg gtatgactag ctgaagcaat attgtggacg cacttataga
     4201 gaatttttct cgcgtaagga tttccacgct tggtgatatg ttcttgagct aggaaattgc
     4261 cagattcata gtgtctgagg tcaatactga taaaggcatt gatttggttg gcagaccgaa
     4321 agcgacgaat gtctccaatt cgccaataat gcttgtagct gttgtttctg cgataccagg
     4381 aatagagagc agaatctcgt attcaggtaa tggttcagcc aattcaatca tttgtgctaa
     4441 gtcctgatcc ttgcggtttg tcagtctcaa cagttcctgt gcatgatact taacctcttc
     4501 tgtcatggga gaggtttttg aaatggcaag ataggactgt tcggccagct cgctcaactt
     4561 ttcagccaat cgtccaactc tgttctcaga aatccgttta gaagttgaat tacgatggct
     4621 tcttttagct caactactga taatttcagc ctccaatgct tggttggaaa gatggtcacg
     4681 aggttccaat attgttcccc tgtaggagta gagagaaggt tctttatttc tggaaaggca
     4741 atttgaagca ccttgtgcag gctattctta gtcctaacga tgtcttctgt cagattctga
     4801 tagaatcgac tgaggtcacg caaattttga tagacttctt cttgaacata agttggtttg
     4861 cggttaagga tgaattgtga cgaagctagc ttttcagcgt caatctgatt ggttttacgg
     4921 actcgcaaac tgtctagttg cttcttagtt ttaaaggatt tagccgtata taagcatagc
     4981 tattgtcctc cagaaaggcc tgaagacgag aatagacccc tgtgcctcga agataatctc
     5041 aggtgtattt acctatttca aatcctctag aagacgacta aatccgatgg catcattggg
     5101 catggtatag ccatgaacct tttcaccatt cacaagaata gcgacttctg agcttgcctt
     5161 actcacatcc attctgaaaa ctgtccgcat catgtttacc cctttgtctt gaatgactcc
     5221 ttgttttagt gattttattt ccaatactcg acgtctagta tcccacatac tttgataaaa
     5281 ttcttcctaa aacaggtttc ttgccagttt gtcaagcgac gtctagcacc atagagagct
     5341 ctatgactta acaagacacc actattttaa cacaaagaaa aagtaatgag tactctctcc
     5401 cgttggagat tttctcacta ctaatcttag tatgtttgtc aactgtagtg atagacgaat
     5461 aatcaagttc tggagaaggt cagattgggc gattacttat tattttccta gcttgtacgg
     5521 tgcttttatc gctatgaaaa agtttattcc aaaatctttt tttagtaact tatagcttac
     5581 ttactgttat accaactatt tctaaaatct tataaattat tttatgcata ttttgcataa
     5641 aattccaaat ttgataatct tcaaattaca atattagtaa gaggattatt aatgtatatc
     5701 agattaaaga atttaagaga agacaaagat ttgtcccagt gtcaaattgc acagtatctt
     5761 cattgttcac agtctgctta ttctagaata gaaagtggca agcaagatat tcctacatca
     5821 tttttgaaac aattagctaa attatatcag gtaactacag attatatttt agagatggat
     5881 aagtttagtt gttaataaat cctaagccct ttgaaaactg aataaaccga ggtgggactt
     5941 tcttatttgt cgagcacttt agcttgatac gccgtgatag gagcgataat tattagctat
     6001 aaaatagagt ggttctctat ctgccatgac tacaaataag gataatgata cttctgaacg
     6061 ttcaggctgc cagcgaaaaa ggacagcggg tgaaatgccc atgaatgatt taaccagtca
     6121 tacccacgga ggaaattata catgttacaa ggaggaaaaa gtttggaaca atcagtaata
     6181 aagtatacta tgcaactatc aatgcttaac tttttatact caagaaatat gttatctaaa
     6241 aatgagtatg acaagattag aaacaaactg cgtattaagt acacaaaata gctgactttt
     6301 tgatttgaat gcggtaatat agaatcaaaa ggaggaattt cagtatgaaa aaaaataatg
     6361 ttgaaataat aaaagctgat tctttagttc gtcgaagagg cgacaatgta gaaagacact
     6421 taaagagggt tgctgcttat tgcagagtta gttccgatag tgaggatcag aaaaacagtt
     6481 atgattctca agtaagacac tacaaagaat atatttctca gcgttcagat tgggagctgg
     6541 cagatattta tgcagatgaa ggtatttcag gaacacaagt aggaaagaga caagattttc
     6601 aacgattaat caatgattgt gcaaatggag agatagatta tattgtcaca aaagcaattg
     6661 ctagatttgc aaggaatacc ctagatactt tgaagtatgt cagaatgtta aaggatatgc
     6721 aaattggagt atattttgag gaagaaaaca tagataccct aacaatggat ggagaattgc
     6781 ttctaactat tctaagctcc gttgcacagc aagaagtaga gaatacttct gcccatgtga
     6841 aaaaaggatt aaaaatgaag atgcaacgtg gtgaattggt tggttttcaa gggtgcttag
     6901 ggtatgatta tgatgtagaa accaagcaga tttcaattaa taaaaaagaa gccaaaattg
     6961 ttcgttatat ttttgaaagg tatctagaag gtattggagg aaaagtaatt gcaagggaac
     7021 ttgatgaact tggttacaaa tcgccaagag gtttagaaca ctggaatgat acaacagttc
     7081 taggaataat aaagaatgaa aaatataaag gtgatattct aatgggaaaa acttttacag
     7141 ttgacccaat aagcaagaga cggttgagta attttggaga agaagataag tactatatca
     7201 aggataatca tgaaccaata atatctaaag aagattttga aaaagctcag gagattagat
     7261 tgcgtcgagc aggaaataag aagacagctg cgaatgtaaa tgggaagcgt gaacgctatt
     7321 caaaaatgta tgcttttagt agcatgttgg aatgtggttt ttgtggttca atattatcta
     7381 gaagaagttg gcactgccgt tcagattatc gcaaagttgt gtggcactgt gttacatcga
     7441 taaagaaagg aaagaaattt tgtaagcata gtaaaggatt agaagagatc gccattgagg
     7501 gggctttcct ggaagcttac agacaagtct atcattcaaa tgaaaattta atgacagact
     7561 tacttgaaac gatagaatct gaattgaatg acaatagcct taacaaggaa ctaaaaagga
     7621 ttacaaacaa acttcgaata ttactaaaaa aagaggagaa tcttgtaaat ctaaggctcg
     7681 aaggaaaagt tagcgattcc atatacaatg aaaagtacaa tgaaatttcc tcagaaaaag
     7741 agtttctagc agaagagaag gtaaatattg aaacaacatt aaaatcagaa atcgatgtaa
     7801 agaaaagact aactgagttt aagcacttgc tatcttcgca aaaaatgctt acggagtttg
     7861 atcgtgcagt ttttgaaagt attgttgaga aaattattgt aggtggagtt aatagcaacg
     7921 gagaaattga tcctgcaatg ttaaccataa tattcaaaac aggtgaaatt caaaacaagg
     7981 atggtaaaca atttaaaagt aaacgtaaaa atgctaaact agaaacagat aaattgtgtc
     8041 ctcaaaacag tgacgaggat aaaaaattgt attctcaagg aacagacaac acacgtggag
     8101 tgtgtagtgt tgctggttcg atcttagcca gtcaataaaa tgatatgttt taaaaaaatt
     8161 ataatttcga aacgtgaata aacttgttta aactttatgt atctttagaa agtgtgttaa
     8221 cttgaaagaa caaatttttt tgatgggtgg gaatccccca ataaagaaat atagtattgt
     8281 tgataaaatt gtattatcaa ccaagattaa aagaattatc atttttacag tttttcgaga
     8341 aaattgggaa ccgtacatga aaaagtacac ggaagttttt caaagtcaat ttcctaatct
     8401 aaacattgat tacttgctcc tggacactga gcagattgat cttgatagct atctagatgc
     8461 tgacataatt atcatcggtg gtggaaatac ggaaaaatat attgctactt atattaatca
     8521 ggagttcaaa agttatatcg atcatatgct taataaagag gcaaaaatta taggattttc
     8581 tgcaggaccc ctactattag gagaaaaagt ctatgtctca cctaatgata attcagatca
     8641 tcagataaag ataaaaaatg gattaggact ctttagtcag tttttaatta gtgtccatta
     8701 tgattcctgg aatgataaag caaataagga tagagctgaa gaactcgata atgttcccat
     8761 aattccacta aatgatcatt cttgtcttgt attggataaa cttggaaaca tcatagagaa
     8821 aattgactaa ctttcataat gtaaaaatgg atctaggaaa taaaagtgta gacgaactgg
     8881 ataggttact agtgaaaact gcaaaaagtg ttgtaaagtg aatcggagtg tgcttgatgg
     8941 attttagtag taagatagcc ataaataaag gctggtcaga tgataaaaaa tattgtgtga
     9001 cagatcaaaa tcagtaaaaa tatttcttgc gtgtttctga taagtcgaag ttagattata
     9061 aaaaaatttg aatttgatat gatggagaaa gtagcttctc ttggagttcc gatgtgtaaa
     9121 ccaattagca ttgaactctg cgatgacgaa gtacattctt tacacgaatg gatagacgga
     9181 agagatgcaa tagatagcat tttaacttat tcagaaaacc aacaatacac atatggtgta
     9241 gaagcaggaa agatacttag aaagattcat acaattcctg ctacagaagt ttgtgaagat
     9301 tgggaaatct tttttaatct aaaaattgat gataaaatct ccaacgaaat gatatggtaa
     9361 gtccgaaacg ctcagtgtgt aagcttgttg ctaaaagcgt aaaaaccttg gaacgaaagg
     9421 aataatagac ttcctgcgaa acaaaaatac aatacaataa aactatggat gatgaagcaa
     9481 gtaaacaatt aagcgatagc cgtttcaaga gccttgtagg tgttcagcgc acgagatgtt
     9541 agctgtgtta aaaacagctt atcaacgcaa cgtaaacgcg caaaaggtgg acgaaaaacc
     9601 aaattaagcc tagacgatct cctcatggta actattcaat acatgcgaga atagcgcact
     9661 tatgaacaaa ttgcggctga ttttggcatt cacgaaagca acttaatccg tcggagccaa
     9721 tgggttgaag taactcttgt tcaaaatggt tttacgattt caaattctgc cctaattatg
     9781 aaaaacagta aaattcgaag gattgtaagg taagagtttt tttctttctg aaaaaatggt
     9841 ataatagcaa tcaaaactag aaaataaaac ggaatttgga acagatttgt ctgtatccta
     9901 gtagagtggt gatgctatga agattagtaa gaggcactta ttaaattatt ccatcttgat
     9961 tccctacttg cttttatcta ttttgggctt gattgtggtc tattcgacca ccagtgctat
    10021 tttaattgaa gaaggcaaga gcgccttgca gttggttcga aaccaaggaa tcttttggat
    10081 tgttagtttg atactgattg ccttaattta taaattgaga ctagattttt tgagaaatga
    10141 gcgactaatc attttagtta tattaataga aatgctttta ttgttcttgg ctcgttttat
    10201 tggtatttcc gtaaacgggg catacggttg gatttcggtt gcaggaataa ctattcagcc
    10261 agctgagtac ttaaaaatca ttattatttg gtatttagct caccgattct ccaaacagca
    10321 agaagaaata gctacttatg attttcaagt tttgactcaa aatcaatggc ttccccgtgc
    10381 ttttaatgat tggcgattcg ttctcctagt tctgattgga agtttgggaa ttttccctga
    10441 tttaggaaat gcgactattt tagtcttggt ttccttgatg atgtatacag ttagtggaat
    10501 cgcttatcgc tggttttcaa ccattctggc gctcgtatct gccgcttctg tctttgtctt
    10561 gaccactatc agcctaatcg gtgttgagac cttttcaaaa attccagtat ttggctatgt
    10621 agccaagcgc tttagtgcct tttttaatcc ttttgccgat cgtgctgatg caggtcacca
    10681 gttagctaat tcttattttg ccatggtcaa tggcggttgg tttggtctag gtcttggaaa
    10741 ctcgattgaa aaacgaggtt atttgccaga agctcataca gactttgtct tttctatcgt
    10801 gattgaagaa tttggctttg ttggtgccag tcttatttta gctctcttgt ttttcatgat
    10861 tttgcggatt atcttggtcg gtatccgagc ggagaatcct ttcaatgcca tggttgcact
    10921 cggtgtcgga gggatgatgt tggttcaggt atttgtcaat atcggaggga tttcgggctt
    10981 gattccatct acaggagtga ctttcccctt cttatcccag ggtggaaata gtcttctagt
    11041 cttatcagtg gcagtagcct ttgtcttaaa tattgatgcc agtgaaaaac gcgctaaatt
    11101 gtaccgagaa ttggaaaatc aaccaatgaa ccttctgttg aagtaggata aagaaaggat
    11161 agtttatgtc tcttcaaaaa ttagaaaatt atagtaataa aagtgttgtg caagaagaag
    11221 tcttgattct aacagaatta ctggaagata ttactaaaaa tatgcttgcc ccagagacct
    11281 ttgaaaaaat aatacagttg aaagaattat caacgcagga agattatcaa ggtctaaacc
    11341 gtctagtgac tagcttatca aatgatgaaa tggtctatat ttcacgctat ttctctatct
    11401 tgcctctttt gattaatatt tcagaggatg tggatttagc ttatgaaatc aatcatcaaa
    11461 ataatattga tcaggactat ttaggtaaat tatctacaac gattaaattg gtagcagaaa
    11521 aggaaaatgc cgttgagatc ctagaacact tgaatgttgt ccctgttttg acagcccatc
    11581 caacacaagt gcaacgcaaa agtatgttgg atttaacaaa tcatattcat agtcttttgc
    11641 gtaaataccg tgatgttaag ttggggttga tcaataaaga taaatggtac aatgatttgc
    11701 gtcgttacat cgaaattatc atgcagacag acatgattcg tgagaaaaaa ttaaaagtga
    11761 ctaacgaaat cacgaatgct atggaatatt ataacagctc ctttttgaaa gctgtacctc
    11821 atttgacgac ggagtataag cgcttagcgc aagcgcatgg tctgaattta aaacaggcta
    11881 aaccaatcac catgggtatg tggataggtg gtgaccgtga tggaaatcca tttgttacag
    11941 caaagacctt gaagcagtct gcactcactc agtgtgaagt catcatgaac tactatgata
    12001 aaaagattta ccaactttat cgtgaatttt ctctttcaac tagcattgtc aacgtcagca
    12061 agcaagtcag agaaatggct cgtcaatcca aggataactc gatttaccgc gaaaaagagc
    12121 tttaccgtcg tgccttgttt gatattcaat caaaaattca ggcaactaaa acctatctga
    12181 ttgaggatga agaagttggg actcgttatg aaaccgccaa tgatttctac aaggatttga
    12241 ttgccattcg agattctcta ctagaaaata agggcgagtc cttgatttca ggtgattttg
    12301 tggaattatt gcaggcagta gagatatttg gtttttactt agcatcaatt gatatgcgac
    12361 aagactctag cgtctatgaa gcctgtgtgg cagaactctt gaaatcagca ggaattcatt
    12421 ctcgttatag cgagttgagc gaagaagaaa agtgtgacct tctcttgaaa gaattagaag
    12481 aagatccccg aattctttct gcgactcacg cagaaaaatc agaattatta gcaaaagaac
    12541 tagctatttt taagacggct cgtgttttga aagataagtt gggagatgat gtcatccgtc
    12601 agaccatcat ttcacatgca accagccttt ctgatatgct agaattagct attctgttaa
    12661 aagaagtagg actggtggat acggaaaggg cgcgtgttca gattgttccc ctttttgaaa
    12721 caattgaaga cttggatcat tcagaggaaa caatgagaaa atatctttct cttagccttg
    12781 ccaaaaaatg gattgactca cgaaataact atcaagaaat catgcttggc tactctgaca
    12841 gtaataaaga tggcggttac ttgtcatcat gttggaccct ctacaaggct caacaacaat
    12901 tgactgctat tggagatgaa tttggcgtta aggttacctt cttccatggt cgtggtggta
    12961 ctgtcggtcg tggtggtggg ccaacctatg aagccattac atctcaaccg ctcaagtcta
    13021 tcaaggatcg tatccgcttg acggagcagg gtgaagtaat tgggaataaa tacggtaaca
    13081 aagacgccgc ttactataac cttgaaatgc tagtatcggc agctattaac cgtatgatta
    13141 ctcagaagaa gagcgatacc aataccccaa atcgttatga agccattatg gatcaagtag
    13201 tggaccgtag ttacgatatc taccgtgatt tggtctttgg taatgagcat ttctatgatt
    13261 atttcttcga gtcaagtcca atcaaggcta tttcaagttt taatattggt tctcgtccag
    13321 ccgctcgtaa gactattact gaaatcggtg gattgcgtgc tatcccttgg gtattctcat
    13381 ggtcacagag tcgtgttatg ttccctggat ggtacggggt tggttcaagc ttcaaggaat
    13441 ttatcaataa aaatccagag aatattgcta tcttacgaga tatgtaccaa aattggcctt
    13501 tcttccaatc gcttctttca aatgttgata tggttttgtc aaaatcaaat atgaatattg
    13561 cttttgaata tgctaaactt tgtgaagacg agcaagttaa ggccatctat gagactattt
    13621 taaatgaatg gcaagttact aagaacgtta tcttggctat tgaaggacat gacgaactct
    13681 tagctgacaa tccatatcta aaagctagtc tggattaccg tatgccttac tttaatattc
    13741 tcaactatat tcagttagag ttgattaaac gccaacgtcg tggagaattg tccagtgatc
    13801 aagaacgatt gattcatatc accatcaacg gaattgcgac aggattgcgt aattcaggtt
    13861 gataattttc aagagtgaat gctaaaagtg aatatcaaaa aaattctaat agactattga
    13921 caagtagttt aaaaatgata taatttaacc attcagaaaa gtaatcatac aaacttttta
    13981 gagagtctgt ggtagctgaa aacagataag tggcaatgat gaaaattggg ctgaatgcta
    14041 tttagaattt gaaattataa aaattcggta agcacacctt acagtgcatc tcgttattgc
    14101 gagactgagc gatagggaaa ttccctataa ttgaggtggt accgcgcatc gacgtcctca
    14161 cacaagtttt ttgtgtgagg atttttttga tggaggttag tatagaaaga aaacgatggc
    14221 gtcgcttgtt tagataagtg aaatatgtta aaggaaataa aaaggagaaa cagaatgaaa
    14281 aataaacgtt taattggaat tattgctgca ttagcagtct tagtagcagg aagcttgatt
    14341 tattcttcaa tgaataaatc agaagctcag aataataagg atgagaagaa aataaccaag
    14401 attggtgtgc ttcaatttgt gagccatcca tcccttgatt tgatttataa agggatccaa
    14461 gatggacttg cagaagaagg atataaagat gatcaagtta aaattgattt tatgaactca
    14521 gaaggtgacc aaagtaaggt tgcgacaatg agtaaacaat tggttgcaaa tgggaatgac
    14581 cttgtggttg gtatcgcaac accagcagcc caagggttgg ctagtgcaac aaaagaccta
    14641 ccggttatca tggccgctat tacagaccca attggtgcta acttggttaa agatttgaaa
    14701 aaaccaggtg gcaacattac aggggtatct gaccacaatc cagctcaaca acaagttgaa
    14761 ctcatcaagg ctctgacacc gaatgtgaaa acaatcggag ctctttactc aagtagcgaa
    14821 gacaattcaa aaacacaggt cgaagaattt aaggcttatg ctgaaaaagc aggtctgaca
    14881 gtggaaacat ttgcagttcc ttcaacaaat gaaattgcct caactgtcac tgttatgact
    14941 agcaaggtag atgctatttg ggttccaatt gataacacca ttgcatcagg atttccaacg
    15001 gttgtctcta gcaatcaaag ttctaagaaa ccaatttatc ccagtgcgac agctatggta
    15061 gaagtaggtg gtttggcatc agttgtaatt gaccaacatg accttggtgt ggcaacaggt
    15121 aaaatgattg tgcaagtctt gaaaggtgca aaaccagccg ataccccagt caatgtcttt
    15181 tcaactggta agtcagtcat caataaaaaa atagcacaag aactaggtat tactattcct
    15241 gagtttgttc tcaaagaagc aggacaagtc atcgaataaa taaggtaggg aggaggagac
    15301 tcttcccatt ttttaaaaag atgaatatag aaaggattaa ataaaatatg attgtttcca
    15361 ttatttctca aggatttgtc tgggctattc taggtctggg aatctttatg acatttagga
    15421 ttttaaactt tccagatatg acgacagaag gttccttccc tcttggggga gctgttgctg
    15481 tcactttgat aaccaaaggc gtgaacccat ttttagcgac acttgttgct gtaggagcag
    15541 gttgtttggc tggaatggca gcaggccttc tttatacaaa agggaagatc ccaaccttgc
    15601 tctcagggat tttggtgatg acttcttgtc actcaatcat gctcttgatt atgggacgtg
    15661 caaatttagg cctgcttgga accaagcaaa ttcaggatgt tttgcctttt gattcggatt
    15721 tgaatcaact cttgacaggt ctcatctttg tgagtattgt tattgctctc atgctctttt
    15781 tcttggacac taaactcgga caagcctata ttgctacagg ggataatcct gatatggcta
    15841 gaagtttcgg gattcatact ggacacatgg agctcatggg cttggtctta tcaaatggtg
    15901 tgattgccct tgcaggtgcc ctcattgctc agcaagaagg ttatgccgat gtgtctcgag
    15961 ggatcggggt tatcgttgtg gggcttgcaa gtttgattat tggagaagtt attttcaaga
    16021 gtttgagctt ggcagagcgt ttggttacta tcgttgtagg ttctatcgct tatcaatttt
    16081 tagtgtgggc agttatcgca cttggcttta atacaagtta ccttcgttta tacagtgcct
    16141 tgattttagc agtctgcctc atgattccaa catttaagca aacaatcttg aaaggagcca
    16201 agttaagcaa atgacagcaa ttgtagaatt aaaaaatgca accaaaatcg ttaaaaatgg
    16261 ctttgatgaa gaaaagatta ttttaaatga tgtttcctta gaaatttttg aacaggactt
    16321 tatcacgatt ttgggtggaa atggtgctgg taaatcaacc ctctttaaca ctattgcagg
    16381 aaccatatca ctaaccagtg gaactatccg tattttaggt gaggatgtta ccaagttttc
    16441 accagagaag cgcgctaagt atctgtctcg agtcttccaa gatccaaaga tggggacagc
    16501 tcctcgtatg acagtggcag agaatctcct gattgccaag tttcgtggtg aaaagcgtgg
    16561 actatttccg agacgtctgg ctagctataa ggataagttt caggcgacca ttgaaaaagt
    16621 gggaaacggt cttgagaaac acttgaatac accgattgag ttcttatctg gtggacaaag
    16681 acaggctttg agtctcttga tggcaacctt gaagcgacct gaattactct tgttagacga
    16741 gcatactgct gccctggatc caaagactag tgttgctttg atggaattga cagatgaatt
    16801 tgttaagaaa gatcaattga cagcccttat gattacccat catatggaag atgctctcaa
    16861 atatggcaat cgcttgattg tcatgaaaga aggacgggtt atccaagatt tgaaacaaga
    16921 agaaaaagca aaaatgaaaa tctctgatta ttatcaactc tttgaataaa gtagggaaaa
    16981 tgagtgaaat ggtttacttt ttttctgaaa taaagtatac tatataaagt aaactatgat
    17041 aacatggagg tattgtgtat ggttgacaaa caagtcattg aagaaatcaa aaacaatgcc
    17101 aacattgtgg aagtcatagg agatgtgatt tctttacaaa aggcaggacg gaactatcta
    17161 gggctctgtc cttttcatgg tgaaaaaaca ccttctttca acgttgtaga ggacaagcag
    17221 ttttaccact gttttggttg tggtcgctca ggtgatgtct ttaaattcat cgaggagtac
    17281 caaggggtta cctttatgga ggctgtccaa atcttaggtc agcgtgtcgg gattgaggtt
    17341 gaaaaaccgc tttatagtga acagaagcca gcctcgcctt accaagctct ttatgatatg
    17401 cacgaagatg cggctaaatt ttaccatgct attctcatga caacgactat gggcgaagag
    17461 gccagaaatt acctttatca gcggggtttg acagatgaag tgcttaaaca tttttggatt
    17521 ggtttagcac ctccagaacg aaactatctc tatcaacgtt tgtctgatca gtatcgtgaa
    17581 gaggatttac tggattcagg cctgttttat ctctcggatg ccaatcaatt tgtagacacc
    17641 tttcacaatc gcattatgtt tcccctgaca aatgaccaag gaaaggtcat tgccttctca
    17701 ggtcgtatct ggcaaaaaac ggattcacaa acttctaagt ataaaaacag ccgatcgact
    17761 gcaattttta acaaaagtta cgaattatat catatggata gggcaaaaaa atcttctgga
    17821 aaagctagtg agatttacct gatggaagga ttcatggatg ttattgcagc ctatcgggtt
    17881 ggaatcgaaa atgctgtggc gtcgatggga acggccttga gtcgagagca tgttgagcat
    17941 ctgaaaaggt taaccaagaa attggttctt gtttacgatg gagataaggc tgggcaagcc
    18001 gcgatattga aagcattgga tgaaattggt gatatgcctg tgcaaatcgt cagcatgcct
    18061 gataacttgg atcctgatga gtatctacaa aaaaatggtc cagaagactt ggcctatcta
    18121 ttaacgaaaa ctcgtattag tccgattgag ttctacattc atcagtacaa acctgaaaac
    18181 agtgaaaatc tgcaggctca gattgagttt attgaaaaaa tagctccctt gattgttaaa
    18241 gaaaagtcca tcgctgctca aaacagctat attcatattt tagctgacag tctggcgtcc
    18301 tttgattatg cccagattga gcagattgtt aatgagagtc gtcaggtgca aaggcagaat
    18361 cgcatggaaa gaatttccag accgacgcca atcaccatgc ctgtcaccaa gcagttatcg
    18421 gctattatga gggcagaagc ccatctactc tatcggatga tggaatcccc tcttgttttg
    18481 aacgattacc gtttgcgaga agactttgca tttgctacac ctgaatttca ggtcttatat
    18541 gacttgcttg gccagtatgg aaatcttcct ccagaagttt tagcagagca gacagaggaa
    18601 gttgaaagag cttggtacca agttttagct caggatttgc ctgctgagat atcgccgcag
    18661 gaacttagtg aagtagagat gactcgaaac aaggctctct tgaatcagga caatatgaga
    18721 atcaaaaaga aggtgcagga agctagccat gtaggagata cagatacagc cctagaagaa
    18781 ttggaacgtt taatttccca aaagagaaga atggagtaat aatggcaaca aaacaaaaag
    18841 aagtaacaac atttgacgta caggtagcag aatttatccg taatcataag caaaaaggga
    18901 cagcaacaga tgatgaaatc aatgcaagtc tggttattcc ttttaccttg gacgctgatg
    18961 ggattgaaga tctcttgcaa cggattcagg atgcaggcat ttctatcaca gataacgaag
    19021 gaaatccaag tgcgcgtgtt cttagcaatg aagaagaacc agaactcagc gatgaggact
    19081 tgattgggtc aacttctgct aaggtcaatg accctgtccg tatgtacttg aaagaaatag
    19141 gggtcgttcc tctcttgacc aatgaagagg agaaagagtt ggcactggct gttgaagctg
    19201 gcgatatcga agccaaacaa cgtcttgcgg aagccaatct tcgtttggtt gtttccattg
    19261 ccaaacgcta tgtcggtcgt ggcatgcagt tccttgactt gattcaagaa ggaaatatgg
    19321 gcttgatgaa ggcggttgac aagtttgact attctaaagg gttcaagttt tcaacttatg
    19381 caacttggtg gattcgtcag gctatcactc gtgctattgc ggaccaagct cgtaccatcc
    19441 gtatcccagt tcacatggtt gaaactatca ataaattggt tcgtgaacag cggaatctcc
    19501 ttcaagaatt ggggcaagat ccgacaccag aacagattgc tgaacgaatg gatatgacac
    19561 ctgataaggt tcgtgaaatc ttgaagattg cccaagaacc agtatctctt gaaactccta
    19621 tcggtgaaga ggacgatagc caccttggag actttatcga agatgaagtg attgaaaatc
    19681 cagtggatta tacgactcgt atcgtcttgc gtgagcaatt ggatgaaatc ttagatactc
    19741 ttacagaccg tgaagaaaat gttctgcgtc tacgttttgg actagatgat ggaaaaatgc
    19801 gcacacttga agatgtgggg aaagtcttta acgtaactcg tgagcgtatc cgtcagattg
    19861 aagcaaaggc tttgagaaaa ctacgccaac caagtcgcag caaaccgctt cgtgatttta
    19921 ttgaagacta agagtgagga aaatatggct tatacagaag agcaaattga aaacatcaaa
    19981 acacggattt taacagcctt ggaagaagtc atcgaccctg agttgggaat cgatattgtc
    20041 aatcttggtt tgatctatga gattcgtttt gacggtgaca cagggcaaac agagattgac
    20101 atgactttga caactatggg ttgtccctta gcagaccttt tgacagacca gatttatgat
    20161 gctatgatag aggttccaga agtaacggat actgaggtta aattagtctg gtatccagcc
    20221 tggacagttg aaaaaatgag tcgctatgcc cgcattgccc taggcattaa gtaaacatat
    20281 aaaagcatgt gagagactgt tggaaaagcg aggaaatttc ccctcttttc ctctagtctc
    20341 tcctttcttt tgctgatttt attcaaagaa aatgatataa tagtagttat ggagaaaaag
    20401 aaattacgca tcaatatgtt gagttcaagt gagaaagtag caggacaggg agtttcaggt
    20461 gcttaccgtg aattagttcg tcttcttcac cgtgctgcca aggaccaatt gattgttaca
    20521 gaaaatcttc cgatcgaggc agatgtgact cactttcata cgattgattt tccctattat
    20581 ttatcaacct tccaaaagaa acgctcaggg agaaagattg gctatgtgca tttcttgcca
    20641 gctacacttg agggaagttt gaaaattcca tttttcttaa agggaattgt gaaacgctat
    20701 gtattttctt tttacaaccg gatggagcac ttggttgtgg tcaatcctat gtttattgag
    20761 gatttggtag cagctggtat tccacgtgaa aaagtgacct atattcctaa ctttgtcaac
    20821 aaggaaaaat ggcatcctct accacaagaa gaggtagtca gactgcgcac agatcttggt
    20881 cttagtgaca atcagtttat cgtagtaggt gctgggcaag ttcagaaacg taaagggatt
    20941 gatgacttta tccgtctggc tgaggaattg cctcagatta cctttatctg ggctggtggc
    21001 ttctcttttg gtggtatgac agatggttat gaacactata agaaaattat ggaaaatccc
    21061 cctaaaaatt tgatttttcc aggcattgta tcgccagagc ggatgcgcga attgtatgct
    21121 ctagcggatc ttttcttgtt gcctagttac aatgagctct ttcctatgac tattttagaa
    21181 gctgcgagtt gtgaggctcc tattatgttg cgtgatttag atctctataa ggtgattttg
    21241 gagggaaatt atcgggcgac agcgggtaga gaagagatga aagaggctat tttggaatat
    21301 caagcaaatc ctgctgcctt aaaagatctc aaagaaaagg ctaagaatat ttccagagag
    21361 tattctgaag agcatctgtt acaaatctgg ttggactttt atgagaaaca agccgcttta
    21421 gggagaaagt aaaaagtgag gtaatctatg cgaattggtt tatttacaga tacctatttt
    21481 cctcaggttt ctggtgttgc gaccagtatt cgaaccttga aaacagaact tgaaaagcag
    21541 ggacatgctg tttttatctt tacgacgaca gataaggatg tcaatcgcta cgaagattgg
    21601 caaattatcc gcattccaag tgttcctttc tttgctttta aggatcgtcg ctttgcctac
    21661 cgaggtttta gcaaggcact tgaaattgct aaacagtatc agctagatat tatccatact
    21721 cagacagaat tttctcttgg cctgttgggg atttggattg cgcgtgaatt gaaaattcca
    21781 gtcatccata cctatcacac ccagtatgaa gactatgtcc attatattgc taaggggatg
    21841 ttgatccgac cgagtatggt caagtatctg gttagaggtt tcctgcatga tgtggatggg
    21901 gttatttgcc ctagtgagat tgtccgtgac ttgctatctg attataaggt caaggttgaa
    21961 aaacgggtca ttcctactgg gattgaatta gccaagtttg agcgtccgga aatcaagcag
    22021 gaaaatttga aagaactgcg tagtaaacta gggattcaag atggtgaaaa gacgttgctt
    22081 agtctttcga gaatctccta tgaaaaaaat attcaagcag ttttagtagc ctttgctgat
    22141 gttctgaaag aggaagacaa ggttaaactg gtagtagctg gggatggccc ttatctgaat
    22201 gacctcaaag agcaagccca gaacctagag attcaagact cagtcatctt tacagggatg
    22261 attgctccta gtgagacggc tctttactat aaagcggcgg attttttcat ttcggcatcg
    22321 acaagcgaaa cgcaaggttt gacctacttg gaaagcttag ccagtggaac acctgtcatt
    22381 gctcacggaa atccttattt gaacaacctc atcagtgata aaatgtttgg aaccttgtac
    22441 tatggagaac atgatttggc tggtgctatt ttggaagccc tgattgcaac accagacatg
    22501 aacgagcata ccttatcaga gaaattgtat gagatttcag ctgagaactt tgggaaacga
    22561 gtgcatgagt tttatctgga tgccattatt tcaaataact tccagaaaga tttggctaaa
    22621 gatgatacgg tcagtcagcg tatctttaag acagttttgt atcttcagca acaggtggtt
    22681 gctgtacctg taaaaggatc tagacgcatg ttgaaggctt caaaaacaca gttgatcagt
    22741 atgagagact attggaaaga ccatgaagaa tagaaagagg aacagctatg aaaaaaacaa
    22801 ttaatgagaa gcggtcgtga taaaaagatt gcgggtgttt gtgctggggt ggcccattat
    22861 ctggatatgg atccgactat cgttcaagtc atttggggtg ttcttacttg ctgttacgga
    22921 gctggaattg tagcttacat tattttatgg attatcgtac cagtagcaac tgactattga
    22981 aaactagctc aattcatgct aagataatag aaaatagaat gtaacgaagg agagaaaaat
    23041 ggcatttgga gataatggaa atcgtaaaaa aactatgttt gagaaaataa ccttgtttat
    23101 cgtgattatc atgctagtag caagtttatt gggaattttt gcaactgcaa ttggtgccct
    23161 cagtaatcta taaaatagat tcaagaaaat ttagtgactg ggatttccca gccctttttt
    23221 aaagtgagaa gaaataatga gtatgttttt agatacagct aagattaagg tcaaggctgg
    23281 taatggtggc gatggtatgg ttgcctttcg tcgtgaaaaa tatgtcccta atggaggccc
    23341 ttggggtggt gatggtggtc gtggaggcaa tgtggtcttc gttgtagacg aaggattacg
    23401 taccttgatg gatttccgct acaatcgtca tttcaaggct gattctggtg aaaaagggat
    23461 gaccaaaggg atgcatggtc gtggtgctga ggaccttaga gttcgagtac cacaaggtac
    23521 gactgttcgt gatgcggaga ctggcaaggt tttaacagat ttgattgaac atgggcaaga
    23581 atttatcgtt gcccacggtg gtcgtggtgg acgtggaaat attcgtttcg cgacaccaaa
    23641 aaatcctgca ccggaaatct ctgaaaatgg agaaccaggt caggaacgtg agttacaatt
    23701 ggaactaaaa atcttggcag atgtcggttt agtaggattc ccatctgtag ggaagtcaac
    23761 acttttaagt gttattacct cagctaagcc taaaattggt gcctaccact ttaccactat
    23821 tgtaccaaat ttaggtatgg ttcgcaccca atcaggtgaa tcctttgcag tagccgactt
    23881 gccaggtttg attgaagggg ctagtcaagg tgttggtttg ggaactcagt ttctccgtca
    23941 catcgagcgt acacgtgtta tccttcacat cattgatatg tcagctagcg aaggccgtga
    24001 tccatatgag gattacctag ctatcaataa agagctggag tcttacaatc ttcgcctcat
    24061 ggagcgtcca cagattattg tagctaataa gatggatatg cctgagagtc aggaaaatct
    24121 tgaagaattt aagaaaaaat tgtctgaaaa ttatgatgaa tttgaagagt taccagctat
    24181 cttcccaatt tctggattga ccaagcaagg tctggcaaca cttttagatg ctacagctga
    24241 attgttagac aagacaccag aatttttgct ctacgacgag tccgatatgg aagaagaagc
    24301 ttactatgga tttgacgaag aagaaaaagc ctttgaaatt agtcgtgatg acgatgcgac
    24361 atgggtactt tctggtgaaa aactcatgaa actctttaat atgaccaact ttgatcgtga
    24421 tgaatctgtc atgaaatttg cccgtcagct tcgtggtatg ggggttgatg aagcccttcg
    24481 tgcgcgtgga gctaaagatg gggatttggt ccgcattggt aaatttgagt ttgaatttgt
    24541 agactaggag actggtatgg gagataaacc gatatctttc cgagatgcgg atggtaattt
    24601 tgtttccgcc gcagacgttt ggaatgaaaa gaaattggaa gaactattta atcgtctcaa
    24661 tccaaatcgt gccttgagat tggcacgaac taaaaaggaa aatccatctc agtaaagaag
    24721 ctaaaaaatc ccggctcttt gtcaactgta gtgggttgaa gaaaagctaa gctcgagaaa
    24781 ggacaaattt tgtcctttct tttttgatat tcagagcgat gaaaatccgt tttttgaagt
    24841 tttcaaagtt tcgaaaacca aaggcattgc gcttgataag tttgatgaga ttattggtcg
    24901 cttccagttt ggcattagaa tagtgtagtt gaagggcgtt gacaatcttt tctttatctt
    24961 tgaggaaggt tttaaagaca gtctgaaaaa taggatgaac ctgcttaaga ttgtcctcaa
    25021 taagtccgaa aagtttctct ggttccttat tctggaagtg aaaaagcaag agctgataga
    25081 gctgatagtg atgtttcaag tcttccgaat agctcaaaag cttgtttaaa atctctttat
    25141 tggttaaatg catacgaaaa gtaggacgat aaaaacgttt atcactcagt ttacggctat
    25201 cctgttgaat gagtttccag tagcgcttga tagccttgta ttcatgggat tttcgatgaa
    25261 actgattcat gatttggaca cgcacacgac tcatagcacg gctaagatgt tgtacaatgt
    25321 gaaagcgatc aagaacgatt ttagcattcg ggagtgaaac agtctgggag actgtttcag
    25381 cctgagccta gaaatttgaa agcgaagctg tttagccaag ccatagtaag ggctaaacat
    25441 atccatggta atgattttga cgcgacatcg gacggctcta tcatatttaa gaaagtgatc
    25501 tcggatgaca gcttgtgttc tgccttcaag aacagtgatg atattgagat tgttaaaatc
    25561 ttgcgcaata aagctcatct ccatctcccg attgaaacag tcactccccg gactgtttca
    25621 acgtcccagg acataatctc aggaagacaa gaaaaatcat gtttaaagtg aaaatcattg
    25681 agcttacgaa taacagttga agttgaaatg gccagctgat gagcaatatc ggtcatagaa
    25741 atcttctcaa tcaacttttg cgcaattttt tggttgataa tacgaggaat ttggtgattt
    25801 ttcttgacga tagaagtttc agcgaccatc atttttgaac agtgatagca cttgaatcga
    25861 cgctttctaa ggagaattct agtaggcata ccagttgtct caaggtaagg aatcttagac
    25921 ggtttttgaa agtcatattt cttcaattgg tttccgcact cagggcaaga tggtgcgtcg
    25981 tagtccagtt tggcgatgat ttccttgtgt gtatctttat tgatgatgtc taaaatctgg
    26041 atattagggt ctttaatgtc tagtaatttt gtgataaaat gtaattgtcc catatgaatc
    26101 tttctaatga gttgttttgt cgcttttcat tatagatctt atgggatttt gtggtacgac
    26161 aggcatgtat agcaaactga atctggaata gcacagcata tcttctaaaa tattgttata
    26221 aattgatttg aatttcaaaa ttaaattgtt tgattcttat ttcaatttgt tatagtatat
    26281 ctgatgtcaa agttctcggc gaatcaaata gcgattccca agcctgacta tcgtgaggta
    26341 gcggattaaa atggtctggg gatagaccgt tttaagtctg acgctggaaa taagaattgt
    26401 cagaagaagg gatagcgaaa tcgtggctct acgaacagga acgtgataat aaggcgtata
    26461 tagcggataa gagggcctca aactctaaag tccaaaaagg tagtcgtaac ctatatgcgt
    26521 aaatcacgag agtaattgaa ttcgtactaa gattttctat tttcactgta accttttaac
    26581 gtcctcatat cttgtataca cgaggaaaga tgtacgactt atcccgtgag gtctatcact
    26641 ataaagagaa aacgacagat agaagtgatc ctgagtcacg gttatcttta aaatagattg
    26701 tctgatagga tgctagcctg aaaacgtctt gttcatgaaa tataggacgg tatgtataaa
    26761 acgcttctgt gaactgagag aagggggaga agttcttgct aaaatttagt tgaacagccg
    26821 tattccgata tttagataag agatctagtc ttagctccta ctcggtttca ggggataaaa
    26881 aaggggcaat agcgattcga gaaagattat actcttcgaa aatctcttca aatcacgtca
    26941 atatcgcctt gccgtacgtg taggatactg actacgtcag ttccatctac aacctcaaaa
    27001 cagtgttttg agcaacctgc ggctagtttc ctagtgtgat ctttgatttt tattgagtat
    27061 tagtaattca gttactaact cgtcaactct gatttatcca ataaaattga aaaggatgga
    27121 aaaaaggata aatttatgat atactttatt ttgaagacct tattagaaat cttgaaagag
    27181 tattgaaaac ttagaatgag aaaaattgtt atcaatggtg gattaccact gcaaggtgaa
    27241 attactatta gtggtgctaa aaatagtgtt gtggccttaa ttccagctat tatattggct
    27301 gatgatgtgg tgactttgga ttgtgttcca gatatttcgg atgtagccag tcttgtcgaa
    27361 atcatggaat tgatgggagc tactgttaag cgttatgacg atgtcttgga gattgatcca
    27421 agaggtgttc aaaatattcc aatgccttat ggtaaaatta acagtcttcg tgcatcttat
    27481 tatttttatg ggagcctctt aggccgtttt ggtgaagcga cagttggtct accgggagga
    27541 tgtgatcttg gtcctcgtcc gattgactta caccttaagg cgtttgaagc tatgggtgcc
    27601 actgctagct acgagggaga taacatgaag ttatctgcta aagatacagg acttcatggt
    27661 gcaagtattt acatggatac ggttagtgtg ggagcaacga ttaatacgat gattgctgcg
    27721 gttaaagcaa atggtcgtac tattattgaa aatgcagccc gtgaacctga gattattgat
    27781 gtagctactc tcttgaataa tatgggtgcc catatccgtg gggcaggaac taatatcatc
    27841 attattgatg gtgttgaaag attacatggg acacgtcatc aggtgattcc agaccgcatt
    27901 gaagctggaa catatatatc tttagctgct gcagttggta aaggaattcg tataaataat
    27961 gttctttacg aacacctgga agggtttatt gctaagttgg aagaaatggg agtgagaatg
    28021 actgtatctg aagacagcat ttttgtcgag gaacagtcta atttgaaagc aatcaatatt
    28081 aagacagctc cttacccagg ctttgcaact gatttgcaac aaccgcttac ccctctttta
    28141 ctaagagcga atggtcgtgg tacaattgtc gatacgattt acgaaaaacg tgtaaatcat
    28201 gtttttgaac tagcaaagat ggatgcggat atttcgacaa caaatggtca tattttgtac
    28261 acgggtggac gtgatttacg tggggccagt gttaaagcga ccgacttaag agctggggct
    28321 gcactagtca ttgctgggct tatggctgaa ggtaaaactg aaattaccaa tatcgagttt
    28381 atcttacgtg gttattctga tattatcgaa aaattacgta atttaggagc ggatattaga
    28441 cttgttgagg attaaaccgt agaggtgttt atgaatattt ggaccaaatt agcaatgttt
    28501 tctttttttg aaacggatcg cttgtatttg cgtcctttct tttttagtga tagtcaggac
    28561 ttccgcgaga tagcttcaaa tccagaaaat cttcaattta ttttcccaac gcaggcaagt
    28621 ctggaagaaa gtcaatatgc actggccaat tactttatga agtccccttt gggagtgtgg
    28681 gcaatttgtg accagaaaaa tcaacaaatg attggttcta ttaaatttga gaagttagat
    28741 gaaatcaaaa aagaagctga gcttggctat tttttgagaa aagatgcttg gtcgcaagga
    28801 tttatgacag aggttgttag aaaaatttgt cagctttctt ttgaggaatt tggcttaaaa
    28861 caattatcta tcattaccca ccttgaaaat gaagctagcc aaagagttgc tcttaagtct
    28921 ggatttagtt tgttccgtca gtttaaggga agtgatcgtt acacaagaaa aatgcgggat
    28981 tatcttgaat ttcggtatgt aaaaggagag ttcaatgagt aagcatcagg aaattctaag
    29041 ctatttggag gaattaccag taggtaaaag ggtcagtgtt cgtagcattt cgaatcatct
    29101 aggagttagt gatggaacag cctatcgggc tattaaagaa gctgaaaacc gtggaattgt
    29161 ggagacccgt cctagaagtg gaacaattcg tgttaaatcc cagaaagttg ctatagagag
    29221 attaacgttt gctgaaattg cagaagtgac ttcttctgag gttctggctg ggcaagaagg
    29281 tttagagaga gaatttagta agttttcaat tggtgccatg actgaacaaa atatcttgtc
    29341 ttaccttcat gatggggggc tcttgattgt cggagaccga acccgtattc agttgctagc
    29401 cttggaaaat gaaaatgcag ttctggttac agggggattt caggttcatg atgatgtgct
    29461 taaactggcc aatcaaaaag ggattcctgt tctaagaagt aagcatgata cctttaccgt
    29521 cgcgaccatg atcaataaag ccttgtcaaa tgtccaaatc aagactgata ttctgacagt
    29581 tgagaaactt tatcgcccta gtcatgagta tggttttctg agagagacag atacagttaa
    29641 agattatttg gacttggttc gtaagaatcg tagcagccgt ttccctgtta tcaatcaaca
    29701 tcaggtcgtt gttggcgttg taaccatgag agacgctggt gataaatcac caagcacgac
    29761 aattgataag gttatgtctc gtagtctatt tttggttgga ttatcgacaa atattgccaa
    29821 tgtgagtcaa cggatgatcg cagaagactt tgaaatggta ccagttgttc gaagcaatca
    29881 aactttgctt ggcgttgtga cgcgacgaga tgtcatggag aagatgagcc gttcccaagt
    29941 ttcggctcta ccaacttttt ctgagcagat tggacaaaag ctctcttatc accatgatga
    30001 agtagtcatt acagtggaac cctttatgct agaaaaaaat ggagttttgg ctaatggtgt
    30061 attggcagaa attctgaccc acatgaccca agatttagtt gttaatagtg gtcgcaatct
    30121 cattatcgag cagatgctga tctacttttt gcaggctgtt cagatagatg atatattgcg
    30181 cattcaggca cggattattc atcatacgag acggtcagct ataattgatt acgatattta
    30241 tcatggtcac cagattgttt caaaagcaaa tgtgactgtt aaaattaatt agaaactagg
    30301 agaaaagatg ataacattaa aatcagctcg tgaaatcgaa gctatggaca aggctggtga
    30361 ttttctagca agtattcata taggcttacg tgatttgatt aagccaggcg tagatatgtg
    30421 ggaagttgaa gaatatgtcc gccgtcgttg taaagaagaa aatttccttc cacttcagat
    30481 tggggttgac ggtgccatga tggactatcc ttatgctacc tgttgctctc ttaacgatga
    30541 agtggctcac gctttccctc gtcattatat cttgaaagat ggtgatttgc tcaaagttga
    30601 tatggttttg ggaggtccca ttgctaaatc tgacctgaat gtctcaaaat taaacttcaa
    30661 caatgttgaa caaatgaaaa aatacactca gagctattct ggtggtttag cagactcatg
    30721 ttgggcttat gctgttggta caccgtccga agaagtcaaa aacttgatgg atgtaaccaa
    30781 agaagctatg tacaagggta ttgagcaagc tgttattgga aatcgtatcg gtgatatcgg
    30841 tgcggctatt caagaatacg ctgaaagtcg tggttacggt gtagtgcgtg atttggttgg
    30901 tcatggtgtt ggcccaacta tgcacgaaga accaatggtt cctaactatg gtattgcagg
    30961 tcgtggactc cgtcttcgtg aaggaatggt cttaaccatt gaaccaatga tcaatacagg
    31021 cgattgggaa attgatacag atatgaaaac tggttgggcg cataagacca ttgacggtgg
    31081 attgtcatgt cagtatgaac accaatttgt cattacgaaa gatggacctg ttatcttgac
    31141 tagccaaggt gaagaaggaa cttattaata aaaagtgaaa agactactgg aagtttatta
    31201 tgaaaaaatc cagtagatct tttcataata aaacgcattg tatcaagtgt taggggctga
    31261 tatcatgcgt ttttctgctt ttaagatttt ttccaactct gtttgtaagc gcatcataac
    31321 aaagggtcta ggattcaggg ctctcctcct atatactatt agtaaagtaa aactaaggga
    31381 ggatatttta gtgtcgcagt ctattgttcc tgtagagatt ccacaatatt gtcgttttga
    31441 ttctaaaaag agaaatggaa ttctgtttaa tgttcgtatt gccaatctta aatttacctt
    31501 ttttagatta gacttcctgc gaaacaaaat atggtatagt agttccatga attatgaagc
    31561 aagtaaacaa ctaactgatg cacgatttaa gcgtcttgtt ggtgttcagc gtaccacttt
    31621 tgaagagatg ttagctgtat taaaaacagc ttatcaactt aaacacgcaa aaggtggacg
    31681 aaaacctaaa ttaagcctag aagaccttct tatggccact cttcaatatg tgcgagaata
    31741 tcgaacttat gaacaaattg cggctgattt tggtattcac gaaagcaact tactccgtcg
    31801 gagccaatgg gttgaagtaa ctcttgttca aagtggtttt acgatttcaa gaactcctct
    31861 cagttctgag gacacggtaa tgattgatgc gacggaagta aaaatcaatc gccctaaaaa
    31921 aagaattagc gaatgattct ggtaaaaaga aatgccacgc tatgaaggct caagcgattg
    31981 tcacaagtca agggagaatt gtttctttgg atatcgctgt gaactattgt catgatatga
    32041 agttgttcaa aatgagtcgc agaaatatcg gacaagctgg aaaaatcttg gctgacagtg
    32101 gttatcaagg gctcatgaag atatatcctc aagcacaaac tccacgtaaa tccagcaaac
    32161 tcaagccgct aacagttgaa gataaagcct ataaccatgc gctatccaag gatagaagca
    32221 aggttgagaa catctttgcc aaagtaaaaa cgtttaaaat gatttcaaca acttatcgaa
    32281 atcatcgtaa acgtttcgga ttacgaatga atttgagtgc tggtattatc aatcatgaac
    32341 taggattcta gttttgcagg aagtctattg aggtattgag ctagtttatg aaaaaattgg
    32401 gtgaaaaagt cgagtgtttt agaaacccac agtgtagtat tctagtttca atccactata
    32461 ttttgctact ccccgtaaag tttctatttt ccctgatttc tgatataata gaaatattga
    32521 cttcaagagt aaggaagaga agatgaacgc attattaaat ggaatgaatg accgtcaggc
    32581 tgaggcggtg caaacgacag aaggtccctt gctaatcatg gcaggggctg gttctggaaa
    32641 gactcgtgtt ttgacccacc gtatcgctta tttgattgat gaaaagctgg tcaatccttg
    32701 gaatatcttg gccattacct ttaccaacaa ggctgcgcgt gagatgaaag agcgtgctta
    32761 tagcctcaat ccagcgactc aggactgtct gattgcgacc ttccactcca tgtgtgtgcg
    32821 tattttgcgt cgcgatgcgg accatattgg ctacaatcgt aattttacaa ttgtggatcc
    32881 tggtgaacag cgaacgctca tgaaacgtat tctcaaacag ttgaacttgg atcctaaaaa
    32941 atggaatgaa cgaactattt tggggaccat ttccaatgct aagaatgatt tgattgatga
    33001 tgttgcttat gctgcccaag ctggcgatat gtatacgcaa attgtggccc agtgttatac
    33061 agcctatcaa aaagaacttc gtcagtctga atccgttgac tttgatgatt tgattatgct
    33121 gaccttgcgt ctctttgatc aaaatcctga tgttttgacc tactaccagc aaaaattcca
    33181 atacatccac gttgatgagt accaagatac caaccacgct cagtaccaat tggtcaaact
    33241 cttggcttcc cgttttaaaa atatctgtgt ggttggggat gcggaccagt ctatctacgg
    33301 ttggcgtggt gctgatatgc agaatatctt ggactttgaa aaggattacc ccaaagccaa
    33361 ggttgttttg ttggaggaaa attaccgctc aaccaaaacc attctccaag cggccaacga
    33421 ggttattaaa aataataaaa atcgccgtcc taaaaatctc tggactcaaa acgctgatgg
    33481 ggagcaaatc gtttactatc gtgccgatga tgagctggat gaggctgtat ttgtagccag
    33541 aaccatcgat gaacttagtc gcagtcaaaa cttccttcat aaggattttg cagttctcta
    33601 tcggactaat gcccagtccc gtacaattga ggaagccctg ctcaagtcta acattcctta
    33661 taccatggtt ggcggaacca aattctacag ccgtaaggaa attcgcgata ttattgctta
    33721 tctcaacctt attgctaatt tgagtgacaa tattagtttt gagcgtatta tcaacgagcc
    33781 taaacgtgga attggtctag gtacagttga gaaaatccgt gattttgcaa atttgcaaaa
    33841 tatgtctatg ctggatgctt ctgctaatat tatgttgtct ggtatcaagg gtaaggcagc
    33901 ccaatctatc tgggattttg ccaatatgat gcttgatttg cgggagcagc tagaccactt
    33961 aagcattaca gagttggttg agtccgtcct agaaaaaaca ggttatgtcg atattcttaa
    34021 cgcccaagcg actctagaaa gcaaggcacg ggttgaaaat atcgaagagt ttctttctgt
    34081 tacgaagaac tttgatgaca ccactgatgt gacagaagag gaaactggtc tggacaaact
    34141 gagtcgtttc ttaaatgact tggctttgat tgccgacaca gattcaggta gtcaggagac
    34201 atcagaagtg accttgatga ccctgcatgc tgccaaaggt ctcgaatttc cagttgtctt
    34261 tttgattggg atggaagaaa atgtctttcc acttagtcgt gcgactgaag atccagatga
    34321 attagaagaa gagcgccgtc tagcctatgt aggtatcacg cgtgcagaga aaattctcta
    34381 tctgaccaat gccaactcac gcttgctttt tggtcgtacc aattataacc gtccgactcg
    34441 ttttattaac gaaatcagtt cagacttgct tgagtatcaa ggtctggctc gtcctgcaaa
    34501 tacaagcttt aaggcatcat atagcagtgg tagtatttcc tttggtcaag gtatgagttt
    34561 ggctcaggct cttcaagacc gtaaacgcgg tgctgcccca aaatcaatcc agtcaagcgg
    34621 tcttccattt ggtcaattta cagctggcgc aaaatcagca tctagcgagg caaattggtc
    34681 cattggtgac attgctctcc acaagaaatg gggagaggga actgttctgg aagtttcagg
    34741 tagcggtgct aggcaggaat tgaaaatcaa tttcccagaa gtaggtttga aaaaactttt
    34801 agccagtgtg gctccaattg agaaaaaaat ctaattttcc atccttctca cgaataataa
    34861 agtgaggagg atttttatgt acagtatttc attccaagaa gattcactat taccaagaga
    34921 aaggctggcc aaggaaggag ttgaagcgct tagtaaccaa gagttgctag ctattttact
    34981 caggacagga acacgtcaag ctagcgtttt tgaaattgcc caaaaagtct tgaacaatct
    35041 ttcaagccta acggatttga aaaaaatgac cctgcaggaa ttgcagagtt tgtctggtat
    35101 tgggcgtgtt aaggccatag aattacaagc tatgattgaa ctggggcatc gtattcacaa
    35161 acacgagact cttgaaatgg aaagtattct cagcagtcaa aagttggcca agaagatgca
    35221 gcaggaatta ggggataaaa aacaagagca cctggtggca ctctatctca atactcaaaa
    35281 tcaaatcatc catcagcaga ccatttttat cggttctgta actcgtagta tcgctgaacc
    35341 gcgagagatt ctgcactatg caatcaagca tatggcgact tctcttatct tggtccacaa
    35401 tcatccttca ggagcggtag cgcctagcca aaatgatgat catgtcacta aacttgttaa
    35461 agaagcctgc gaattgatgg ggattgttct cttggaccat ttgattgtct ctcattctaa
    35521 ttactttagt tatcgtgaaa agacagattt aatctaaagt tcattaacga catagtcaaa
    35581 gagtttttta tctttgggac gattttcaaa aagaagttct ggatgccatt ggacaccgag
    35641 aaaggcgaca tcatccgtac tcatgacagc ctcaatgata ccatctttag gatcatgagc
    35701 cacaactttt aaatttggtg ctaagtcctt gatgctctgg tggtggaagg agttgatatg
    35761 agagatttct ccatagattt cttggagaac ggtatctggt tctgttacca agcgttgagt
    35821 tgtgtactca acagaagaat cctgccaatg gtcttcgata tcttggtaca aagttccacc
    35881 catggcaacg ttaaagagtt gggtaccacg gcagacagag aaaatgggct ttttctgttt
    35941 aatagcttcc ttgatgaggg tcagttcgaa gatatctctt tgaaggtgat agtcatcgct
    36001 atcaatggtt ttgggttcgc cataaaattt tggatcgaca ttttgcccac ctgtcaagat
    36061 gagcttgtca atcaaactga tatagtggca ggccatttct tgatcaccaa tcggtaggat
    36121 gatgggaatc cctccagaat ctttaacgcc ttcaacaaag ccttttgctg cgtagctcat
    36181 catgatgtca tcatctggat gagctttttc gtttcctgta atcccaataa ctggtttttt
    36241 cataaaatga ttttcgcttt ctaatcctct tttcgcatga agtagaggag ggtttggagt
    36301 tcacttgtca aatcgacata ctgaacgacc acgtcttttg gtaaatgcag atggactggt
    36361 gaaaaactga gaattccttt cacaccagca tcaaccaaga gattagcaac ctcttgtgac
    36421 ttgacgctgg gaacagttag gatagcagtc ttcacatcag catccttgat tttatccttg
    36481 atctgagaaa tcccgtaaat gggaatcccg tcaggagttt gggtaccgac ttcaggatgg
    36541 tcgtctaggt caaaggccat gataatcttc atcttgttac gttcgtggaa gcggtagtgg
    36601 agaagggcat ggcccatatt tccaatacca accagcatga cattggtaat agagttgtca
    36661 ttgagcaaat cggcaaaaaa tgtcattagt tttttgacat catagccaaa accacgacga
    36721 ccaagttcac caaaatagga aaaatcacga cgtacggtcg ctgaatcaat accgatagcc
    36781 tctgcaattt gcttagagtt ggcacgttca atcttttctg catgaaatct cttaaaaatt
    36841 cgatagtaga gagagagtct ttttgctgta gcttttggaa tagcaaactg tttatctttc
    36901 acaaaatcac aacctttcta ttcttctatt ttatagaaac attgtgaaaa aatcaacaaa
    36961 aataagaaaa aactaagaaa aatcttagtt ttgatgtaaa aaatctgcat gagatagaaa
    37021 acggtagagg tctccgacca gaccctgata aactttttgg cccctaaaag tcagagaagt
    37081 cacataaagt gtatctggta aggttacaca tcctgacaaa gtcaacatga gagcctcatg
    37141 atcctcatac ttgagagtac gctctacatg atagcagtcc ttataggtca gttcaaacat
    37201 tttggctcta tctttccgat tttgtaaaga caccacgttc taccaagcta tccatgagga
    37261 agtagaattt ttcctgatga atatggtggt cttctgattt gaaaatatca actagacgaa
    37321 ggccaaactt gtcagtgata ttgattttag cccctgtaag ttccttgtta atgatgattt
    37381 tgagttggaa gccttcaccg ctgtttggca ctttttccaa aaggcgagtc agttcatagt
    37441 taccaacctt agtttcaaaa aaggtgttat ctttgagggt gaatttttta acagaagggc
    37501 taagagtgta atcgtaacga caatttttta actgaatgat tttttcaaat gccatatggc
    37561 taacctccga taatttcttt taaggttttt gcgagggttt gtaggtcttc aacggtattt
    37621 tgtggcgaca aactgatgcg aagggattcc ttcaagcgtt ctgaatttgc gccatacatg
    37681 gcttcaagaa catggctgga ttggacaacg cctgcagtac aggctgagcc agtagagatt
    37741 gaaattccag ctaaatctag ccgaaggagt aagaggtcat ttttctgacc aggaaatcca
    37801 atattgagaa cataagggag atgatgtttt cctctattca agtaatactg aatgccctcc
    37861 agctctgcca gaaaggcagt ttctagattt tgtacatgtt gaaaatgttc ttcttgtttt
    37921 tctaggtctt cttttagggc tgcaaccatg cctacgatag caggcagatt ttcagttcct
    37981 gcacgttttt tctgttcctg gtctccgcca tgtagatagg aatcaaagtc catgctagat
    38041 gcgtagagaa aaccgattcc cttaggacca tggaatttgt gggcagaagc agtgagaaaa
    38101 tcaatgccca attcttctga atgaattggg attttaccaa tagcctgaac tgcatcaaca
    38161 tgataggcag cagggtgttg cttgagtatt tggccaattt cagcgatggg cagtaggttt
    38221 cctgtctcat tattggcaaa catggtagaa accaaaatcg tatcgtcacg taaagccttt
    38281 tgaatttgct gggctgtgat ttcttgattt tctggctgga taatggttgc ttcaaaccca
    38341 aagtgttgaa ccaagtaatc aattgtttca aggacagcat ggtgctcgat ggcagttgtg
    38401 atgatatgtt ttccttgttc ttggtgacga agacagtagc caatgatggt agtattattg
    38461 ccttcagtcc caccagaagt gaaaaagata tgttgaggtt ttgtccttag taactgggct
    38521 agttcctgac gggcttctcg caagagtttg ccagcttgac gaccatgacc atgaatacta
    38581 gaaggatttc cgtgggtttc ttgcataacc ttggtcatag ctgaaatagc aactgctgac
    38641 ataggagtcg ttgcagcatt gtccaaataa atcaaagaat caccttattt ctttttattg
    38701 taggcaaaga gtgggctgac tggttttctt tcgtgaatac ggacgatagc atcaccaatt
    38761 aactcactag cagtgatgta gcatacattt ttaggagttt tttcttttgt tgctactgaa
    38821 tcagtcacaa gaatttcttt aatattagta ttgtcaagaa gctcagcagc tccctcgacg
    38881 aagagaccgt ggctagaaac agcataaatt tctgtagctc cttcacgttc aacgatttta
    38941 gaagcttcag agaaggtacg tcctgtattt aaaatatcat caatcaagat agctttctta
    39001 ccttcaacat caccaataat ataaccttcg ttacgagttg catcgtcttg agggtagtcg
    39061 ataatggcga taggagcatc aagatattca gccaggctac gcgcacgttt gacacctgaa
    39121 tttttagggc taacgacaac aacatctgaa ccaagcaatc ctttatcgca gtaatgtttt
    39181 gcgaataggg gaacagtgaa aagattatcc actggaatat caaagaaacc ttgaacctga
    39241 acggcatgca aatcaagagt caggatacga tcaactccag ccttaaccag catattggca
    39301 actagttttg ctgtaagtgg ctcacgagga caagcaatgc ggtcttgacg tgcatagcca
    39361 aaatatggaa ggacaacgtt gatactgtgg gcacttgcac gcacacaagc atcgaccatg
    39421 attaacaatt ccattaggtg gttgttgaca gggaaacttg ttgattggat gatgtaaaca
    39481 tcataaccac ggacactttc ttcgatattt acttggattt ctccgtctga aaattgacgt
    39541 gatgatagtt ttccaagtgg ggcaccaaca gcttgggcaa ttttttgtgc aatctcttgg
    39601 ttagagttga gtgcgaaaag tttcatgttt tttctatctg acattataga ccgtcctctg
    39661 taaactttat aaatcctagt tatatttacc ttacatatat gaactgggat ttgtgtattt
    39721 ttatcttttc tattttacca aaaaatggag attatttcag ctatttttca tacttttgac
    39781 aaatcgaacc aattttgaag gagctttttg gtaggaaatc tgatttttct ctaaaaattg
    39841 tcggaaatcc tgtttgcctt gctcatgatt ttccacttca agctccaatt cgtaatctgt
    39901 tatatcaaag tatcggctct gatccagtgc catgagacca atagctgttt tcatttcata
    39961 gcgaagcgtt gttagacaac caagaacctg ccagttctta ctttggatac catgtttcgc
    40021 caattcatcc agtactagcc cttgaggaag ttcttcctta ctcagatagt tctcagcatc
    40081 ttttagttgc aatttttggt tgtattccat gtttccaaca ctctgcggga ctttgagtgt
    40141 caactcagcc cagtcttcaa aggttcgaat gcgcatagcg actttctttt ctcgcagttc
    40201 aaaatcaggc gtgtcgatgt agtaatttgt ttgaagaaca ggagtgacac ctgtgaactg
    40261 gtcttttaga cgattgtatt catctttttt caatagtgtt ttcaattcaa tttctaaatg
    40321 tttcattttt cttacctttt tttatcgttg aaagcggatt tatggtataa taagcattgt
    40381 atttattgta tatgaatctg gagaaaaaat caaagatatt tttgacggat aatatgagaa
    40441 caagggagaa tatatgacct tagaatggga agaatttcta gatccttaca ttcaagctgt
    40501 tggtgagtta aagattaaac ttcgtggtat tcgtaagcaa tatcgtaagc aaaataagca
    40561 ttctccaatt gagtttgtga ccggtcgagt caagccaatt gagagcatca aagaaaaaat
    40621 ggctcgtcgt ggcattactt atgcgacctt ggaacacgat ttgcaggata ttgctggctt
    40681 acgtgtgatg gttcagtttg tagatgacgt caaggaagta gtggatattt tgcacaagcg
    40741 tcaggatatg cgaatcatac aggagcgaga ttacattact catagaaaag catcaggcta
    40801 tcgttcctat catgtggtag tagaatatac ggttgatacc atcaatggag ctaagactat
    40861 tttggcagaa attcaaattc gtactttggc catgaatttc tgggcaacga tagaacattc
    40921 tctcaactac aagtaccaag gggatttccc agatgagatt aagaagcgac tggaaattac
    40981 agctagaatc gcccatcagt tggatgaaga aatgggtgaa attcgtgatg atatccaaga
    41041 agcccaggca ctttttgatc ctttgagtag aaaattaaat gacggtgtag gaaacagtga
    41101 cgatacagat gaagaataca ggtaaacgaa ttgatctgat agccaataga aaaccgcaga
    41161 gtcaaagggt tttgtatgaa ttgcgagatc gtttgaagag aaatcagttt atactcaatg
    41221 ataccaatcc ggatattgtc atttccattg gcggggatgg tatgctcttg tcggcctttc
    41281 ataagtacga aaatcagctt gacaaggtcc gctttatcgg tcttcatact ggacatttgg
    41341 gcttctatac agattatcgt gattttgagt tggacaagct agtgactaat ttgcagctag
    41401 atactggggc aagggtttct taccctgttc tgaatgtgaa ggtctttctc gaaaatggtg
    41461 aagttaagat tttcagagca ctcaacgaag ccagcatccg caggtctgat cgaaccatgg
    41521 tggcagatat tgtaataaat ggtgttccct ttgaacgttt tcgtggagac gggctaacag
    41581 tttcgacacc gactggtagt actgcctata acaagtctct tggcggtgct gttttacacc
    41641 ctaccattga agctttgcaa ttaacggaga ttgccagcct taataatcgt gtctatcgaa
    41701 cactgggctc ttccattatt gtgcctaaga aggataagat tgaacttatt ccaacaagaa
    41761 acgattatca tactatttcg gttgacaata gcgtttattc tttccgtaat attgagcgta
    41821 ttgagtatca aatcgaccat cataagattc actttgtcgc gactcctagc cataccagtt
    41881 tttggaaccg tgttaaggat gcctttatcg gtgaggtgga tgaatgaggt ttgaatttat
    41941 cgcagatgaa catgtcaagg ttaagacctt tttaaaaaag cacgaggttt ctaagggatt
    42001 gctggccaag attaagtttc gaggtggagc tattctggtc aataatcaac cgcaaaatgc
    42061 aacgtatcta ttggacgttg gagactacgt taccattgac attcccgctg aggaaggctt
    42121 tgaaaccttg gaggctattg agcatctatt agatattctc tatgaggatg atcactttct
    42181 agtcttgaat aaaccctatg gagtggcttc tattcctagt gtcaatcact ctaataccat
    42241 tgccaatttt atcaagggtt actatgtcaa gcaaaattat gaaaatcagc aggttcacat
    42301 tgttaccaga ctagataggg acacttctgg cttgatgctc tttgccaagc acggttatgc
    42361 ccatgcacga ttagacaagc agttgcagaa gaaatctatc gagaaacgct actttgcttt
    42421 ggttaaggga gatggacatt tggagccaga aggggaaatt attgctccga ttgcgcgtga
    42481 tgaagattcc attattacca gacgagtggc taaaggcgga aagtatgccc atacttcata
    42541 caagattgta gcttcttatg gaaatattca cttggtctat attcacctgc acactggtcg
    42601 aacccatcaa atccgagtcc atttttctca tatcggtttt cctttgctgg gagatgattt
    42661 gtatggtggt agtctggaag atggtattca acgtcaggct ctgcattgcc attacctatc
    42721 cttttatcat ccatttttag agcaagactt gcagttagaa agtcccttgc cggatgattt
    42781 cagtaacctt attacccagt tatcaactaa tactctataa aaactgtctc agagtataat
    42841 tattatctta aaggagaaaa ctcatggaag tttttgaaag tctcaaagcc aaccttgttg
    42901 gtaaaaatgc tcgtatcgtt ctccctgaag gggaagagcc tcgtattctt caagcaacaa
    42961 aacgcttagt aaaagaaaca gaagtgattc ctgttttgct tggaaatcct gaaaaaatta
    43021 aaatttatct tgaaattgaa ggaatcatgg atggttatga ggtcatcgac cctcaacatt
    43081 atcctcaatt tgaagaaatg gtttctgcct tggtggagcg tcgcaagggc aaaatgactg
    43141 aagaagatgt acgcaaggtt ttggttgaag atgtcaacta ctttggtgtg atgttggttt
    43201 acttgggctt ggttgatgga atggtgtcag gagcgattca ctcaacagct tcaacagttc
    43261 gtccagctct acaaatcatc aaaactcgtc caaatgtaac tcgtacttca ggagccttcc
    43321 tcatggttcg tggtacggaa cgttacctat ttggagactg tgccattaac atcaatccag
    43381 atgcagaagc cttggctgaa attgccatca actcagcaat cacagctaag atgtttggca
    43441 tcgaacctaa aattgccatg ttgagctatt ctactaaagg ttcagggttt ggtgaaagcg
    43501 ttgataaggt cgttgaagca actaaaattg ctcacgactt gcgtcctgac cttgaaatcg
    43561 atggtgagtt gcaatttgat gcagcctttg ttcctgaaac tgcagctctg aaagctcctg
    43621 gaagtacggt agctggtcaa gcaaatgtct tcatcttccc aggtatcgag gcaggaaata
    43681 tcggttacaa gatggctgaa cgcctaggtg gctttgcggc tgtaggacct gttttgcaag
    43741 gtttaaacaa gccagttaat gatctttctc gtggatgtaa tgcagatgat gtttacaagt
    43801 tgaccctcat cacagcagct caagcagttc atcaatagtg aaaactataa agcgatatac
    43861 tatgctatac tgtagttatg aaactatgta cgaaaagcac tgccattaat tcctgagaac
    43921 taaattactg attggtgtca aaaaggaaaa cttccaagcg ataatatcct gtctatacac
    43981 gacctataga aatctgtaat atacatgtcc gtaaaacgat aaattccctt tttgatttta
    44041 aatgagtatg aaaagagaat tttttggctc tttgtcaact gtagtgggtt gaagtcagct
    44101 aagctcgaga aaggacaaat tttgtccttt cttttttgat attcagagcg ataaaaatcc
    44161 gttttttgaa gttttcaaag tttcgaaaac caaaggcatt gcgtttgata agtttgatga
    44221 gattattggt cgcttccaat ttggcgtttg aatagggtag ttgaagggcg ttgacgattt
    44281 tctctttgtc ctttagaaag gttttaaaga cagtctgaaa aagaggatga acctgcttta
    44341 gattgtcctc aataagcccg aaaaatttct cagggtcttt gttctgaaag tgaaacagca
    44401 agagttgata gagctgatag tgatgtttca agtcttgtga atagctcaaa agcttgtcaa
    44461 gaatttcttt atttgttaag tgcatgcgaa aagtagggcg ataaaaacgt ttatcgctca
//
LOCUS       DAVKMJ010000018        41153 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000018 DAVKMJ010000000
VERSION     DAVKMJ010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 41153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41153
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.018"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..413
                     /locus_tag="VW348_000960"
     CDS             <1..413
                     /locus_tag="VW348_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HEU9745879.1"
                     /translation="PKEIKNNENRVALTPAGVHSLVSRGHRVLIETNAGLGSGFTDAD
                     YQKQGAEIVATAGEAWAAELVVKVKEPLSSEYGYLRDVLLLFTYLHMAAAPELADAML
                     AAKITGIAYETVRDNQGQLPLLVPMSEVAGRMAV"
     gene            414..827
                     /locus_tag="VW348_000961"
     CDS             414..827
                     /locus_tag="VW348_000961"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-binding protein"
                     /protein_id="HEU9745880.1"
                     /translation="MGAHFLTKQAGGSGVLPGGVPGVPKGKVTIIGGGVVGTHAARIA
                     LGLGAQVTILDISAKRLSVLEEVFGSQIQTLISNSFNIEASMRDADVVIGAILIPGAK
                     APELVTDEMVKQMRPGSVSLTLLLTKVALSKQLTV"
     gene            773..1099
                     /locus_tag="VW348_000962"
     CDS             773..1099
                     /locus_tag="VW348_000962"
                     /inference="COORDINATES: protein motif:HMM:NF013430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745881.1"
                     /translation="MVDVAVDQGGVIETADRVTTHDEPVYEKHGVLHYAVANIPGAVA
                     RTSTIALTNVTLPYIEALAGKGFAQAISEDEGLRQGVTTYQGYLTSLPVAQGLNRDYT
                     DINDLV"
     gene            complement(1466..1726)
                     /locus_tag="VW348_000963"
                     /pseudo
     CDS             complement(1466..1726)
                     /locus_tag="VW348_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(1729..2229)
                     /locus_tag="VW348_000964"
     CDS             complement(1729..2229)
                     /locus_tag="VW348_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9745882.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVIDFVYAHPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            2265..2444
                     /locus_tag="VW348_000965"
     CDS             2265..2444
                     /locus_tag="VW348_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745883.1"
                     /translation="MTQEDALIVISHIKVLSIVPNRCLKPLDKTFSLYNWIFLSQKYI
                     LLQANFLKISRVQLQ"
     gene            complement(2422..3390)
                     /locus_tag="VW348_000966"
     CDS             complement(2422..3390)
                     /locus_tag="VW348_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEU9745884.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(3476..3691)
                     /locus_tag="VW348_000967"
     CDS             complement(3476..3691)
                     /locus_tag="VW348_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEU9745885.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(3700..4554)
                     /gene="cvfB"
                     /locus_tag="VW348_000968"
     CDS             complement(3700..4554)
                     /gene="cvfB"
                     /locus_tag="VW348_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEU9745886.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGCVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(4614..5171)
                     /gene="frr"
                     /locus_tag="VW348_000969"
     CDS             complement(4614..5171)
                     /gene="frr"
                     /locus_tag="VW348_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEU9745887.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(5180..5917)
                     /locus_tag="VW348_000970"
     CDS             complement(5180..5917)
                     /locus_tag="VW348_000970"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEU9745888.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(6001..7335)
                     /gene="trmFO"
                     /locus_tag="VW348_000971"
     CDS             complement(6001..7335)
                     /gene="trmFO"
                     /locus_tag="VW348_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEU9745889.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            complement(7630..7884)
                     /locus_tag="VW348_000972"
     CDS             complement(7630..7884)
                     /locus_tag="VW348_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEU9745890.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIEAEAIRRNCERGAIFSGKIKYHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            7879..8683
                     /locus_tag="VW348_000973"
     CDS             join(7879..8247,8249..8683)
                     /locus_tag="VW348_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEU9745891.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADFGIHESNLIRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVKINRPKKQLANHSGKKKFHAMKAQAIVTSQGRIVSLDIAVNY
                     CRDMKLFKMSRRNIGQAGKILSDSGYQGLMKIYPQVQTPRKSSKLKPLTAEDKACNHA
                     LSKERSKIENIFAKVKTFKMFSTIYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(8672..9318)
                     /locus_tag="VW348_000974"
                     /pseudo
     CDS             complement(8672..9318)
                     /locus_tag="VW348_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            complement(9427..9945)
                     /locus_tag="VW348_000975"
     CDS             complement(9427..9945)
                     /locus_tag="VW348_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HEU9745892.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(10172..11041)
                     /gene="rsmI"
                     /locus_tag="VW348_000976"
     CDS             complement(10172..11041)
                     /gene="rsmI"
                     /locus_tag="VW348_000976"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEU9745893.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGL
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(11044..11361)
                     /gene="yabA"
                     /locus_tag="VW348_000977"
     CDS             complement(11044..11361)
                     /gene="yabA"
                     /locus_tag="VW348_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEU9745894.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(11401..12291)
                     /locus_tag="VW348_000978"
     CDS             complement(11401..12291)
                     /locus_tag="VW348_000978"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEU9745895.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(12288..12926)
                     /locus_tag="VW348_000979"
     CDS             complement(12288..12926)
                     /locus_tag="VW348_000979"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEU9745896.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLELHKKVRQGYLSLLEKEGNRIVKIDASLPLEQVVETTKAVLFDGMDLAK"
     gene            complement(13146..13943)
                     /gene="proC"
                     /locus_tag="VW348_000980"
     CDS             complement(13146..13943)
                     /gene="proC"
                     /locus_tag="VW348_000980"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEU9745897.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQTRTSDEILLANRSQAKVDAFIAD
                     FGGQASSNEEMFAEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFYQLLAKAGLLVELGES
                     LIDAATGLAGCGPAFVYLFIEALADAGVQTGLPREIALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMDAVHQAYKRTQELGK"
     gene            complement(13947..15209)
                     /locus_tag="VW348_000981"
     CDS             complement(13947..15209)
                     /locus_tag="VW348_000981"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEU9745898.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAIGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVAGDGQIRE"
     gene            complement(15219..16349)
                     /locus_tag="VW348_000982"
     CDS             complement(15219..16349)
                     /locus_tag="VW348_000982"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEU9745899.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(16429..18312)
                     /gene="cbpE"
                     /locus_tag="VW348_000983"
                     /gene_synonym="pce"
     CDS             complement(16429..18312)
                     /gene="cbpE"
                     /locus_tag="VW348_000983"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEU9745900.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYMGQW
                     YYFAPSGEMKMGWVKDKETWYYMDSTGVMKTGEIEVAGQHYYLEDSGAMKQGWHKKAN
                     DWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVSIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNFSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(18315..19202)
                     /locus_tag="VW348_000984"
     CDS             complement(18315..19202)
                     /locus_tag="VW348_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEU9745901.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(19192..19653)
                     /locus_tag="VW348_000985"
     CDS             complement(19192..19653)
                     /locus_tag="VW348_000985"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEU9745902.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(19650..20558)
                     /locus_tag="VW348_000986"
     CDS             complement(19650..20558)
                     /locus_tag="VW348_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEU9745903.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            20551..20748
                     /locus_tag="VW348_000987"
                     /pseudo
     CDS             20551..20748
                     /locus_tag="VW348_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(20800..21471)
                     /locus_tag="VW348_000988"
     CDS             complement(20800..21471)
                     /locus_tag="VW348_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9745904.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(21525..21746)
                     /locus_tag="VW348_000989"
     CDS             complement(21525..21746)
                     /locus_tag="VW348_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HEU9745905.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            22018..22827
                     /locus_tag="VW348_000990"
     CDS             22018..22827
                     /locus_tag="VW348_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9745906.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(23008..23883)
                     /gene="aguB"
                     /locus_tag="VW348_000991"
     CDS             complement(23008..23883)
                     /gene="aguB"
                     /locus_tag="VW348_000991"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEU9745907.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYNLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(23893..24978)
                     /gene="aguA"
                     /locus_tag="VW348_000992"
     CDS             complement(23893..24978)
                     /gene="aguA"
                     /locus_tag="VW348_000992"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEU9745908.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(24975..26102)
                     /gene="nspC"
                     /locus_tag="VW348_000993"
     CDS             complement(24975..26102)
                     /gene="nspC"
                     /locus_tag="VW348_000993"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEU9745909.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLEIMDHIVF
                     NSERQLRKHGPRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(26102..27361)
                     /locus_tag="VW348_000994"
     CDS             complement(26102..27361)
                     /locus_tag="VW348_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEU9745910.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVKKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(27358..28218)
                     /gene="speE"
                     /locus_tag="VW348_000995"
     CDS             complement(27358..28218)
                     /gene="speE"
                     /locus_tag="VW348_000995"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEU9745911.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
     gene            complement(28249..28386)
                     /locus_tag="VW348_000996"
     CDS             complement(28249..28386)
                     /locus_tag="VW348_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001270407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745912.1"
                     /translation="MRYQTHYQLKQKLWLEPFGNRQAIGGNELIHSGLFQVYHLGFGS
                     S"
     gene            28473..29188
                     /locus_tag="VW348_000997"
                     /pseudo
     CDS             28473..29188
                     /locus_tag="VW348_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(29154..30629)
                     /locus_tag="VW348_000998"
     CDS             complement(29154..30629)
                     /locus_tag="VW348_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEU9745913.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            31336..32331
                     /locus_tag="VW348_000999"
     CDS             31336..32331
                     /locus_tag="VW348_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU9745914.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKVPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVRKSSVTKELKEKILHYHNQ
                     KFSPEMMVMVKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKSAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSADVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYASWERGTNENHNRLIRR
                     WLPKGIKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSVRNKSRN"
     gene            32357..33001
                     /locus_tag="VW348_001000"
     CDS             32357..33001
                     /locus_tag="VW348_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEU9745915.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATSNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYASYIQNGEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(33043..35031)
                     /locus_tag="VW348_001001"
     CDS             complement(33043..35031)
                     /locus_tag="VW348_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9745916.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(35033..35791)
                     /locus_tag="VW348_001002"
     CDS             complement(35033..35791)
                     /locus_tag="VW348_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9745917.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            36219..36410
                     /locus_tag="VW348_001003"
     CDS             36219..36410
                     /locus_tag="VW348_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745918.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(36764..37036)
                     /locus_tag="VW348_001004"
     CDS             complement(36764..37036)
                     /locus_tag="VW348_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEU9745919.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(37094..37543)
                     /locus_tag="VW348_001005"
     CDS             complement(37094..37543)
                     /locus_tag="VW348_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEU9745920.1"
                     /translation="MKLTDYVKQVSLEDFGRPFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQELGLDVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPIKLYRCQSCQQTYQRKRRIDTQRYRCGLCRGKLLLVNQPED"
     gene            complement(37530..39659)
                     /locus_tag="VW348_001006"
     CDS             complement(37530..39659)
                     /locus_tag="VW348_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEU9745921.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRSQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYAAVKELFKCL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVAVGD
                     LVSVWVKKIDTEREKVNLSLLAPNETD"
     gene            complement(39761..40765)
                     /locus_tag="VW348_001007"
     CDS             complement(39761..40765)
                     /locus_tag="VW348_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1919 domain-containing protein"
                     /protein_id="HEU9745922.1"
                     /translation="MTENLTNVQVLQKMDDTDHRIRKQYRSLFGKLFNSKLLRKINQF
                     DINNLIWRLYIHSKTATYINFPTYIYKPVIDAKPLKDSYKIILENYENRIKDCAVLEN
                     YDIERAKKQYIQELANFSAWLKNDGEYLDSDIVYHKLIAAEKGIFPFLELDRLDFTII
                     SNNCVGGLIYKQLGFQYRTPFVGLFILPDDYYKLTKHFRYYMEQELVFEEELISPSWT
                     HEVYPLGHLGDIDIHFLHYSSIEEARTKWEKRKKRINWNNLYFKFDNKDSASEEILNK
                     MDNLPYSNKLILVNRPYKNLKSQCVIPGQEHLPELAIMSDPLNTFDIMAWLKKGGNAL
                     "
     gene            complement(40770..41081)
                     /locus_tag="VW348_001008"
     CDS             complement(40770..41081)
                     /locus_tag="VW348_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9745923.1"
                     /translation="MERQTLKDIEVIIVNQSTEEIASISQQMNLSFNIKIIDENSFAE
                     LSDMITGDYITFLSSNDSLFDWTFEKMYHAIKLSDSDVVLGHFADLVDGVFYFYPLGG
                     G"
BASE COUNT        12118 a         9161 c         7555 g        12319 t
ORIGIN      
        1 tcccaaaaga aattaaaaat aacgaaaacc gtgtcgccct cacacctgca ggtgttcata
       61 gcttagttag tcgtggtcat cgtgtcctta tcgaaacaaa tgctggtctc ggttctggct
      121 ttactgatgc tgactatcaa aagcaaggag ctgagattgt cgctactgct ggtgaagctt
      181 gggcagcaga gttggttgtg aaagtaaaag aacctttaag ttctgaatac ggttacttgc
      241 gcgacgttct tcttctcttc acctacttgc acatggccgc tgctccagaa ttagcagatg
      301 ctatgttagc agcaaaaata acaggaattg cctatgaaac tgttcgtgac aatcaaggac
      361 aactaccgct cctcgttcct atgagtgagg ttgcaggtcg tatggctgtt taaatcggag
      421 ctcacttcct tactaagcaa gctggtggct ctggtgttct acctggtggt gtaccaggtg
      481 ttccaaaagg aaaagtaact atcatcggtg gtggtgtcgt cggtacacat gctgcccgca
      541 tcgcccttgg tcttggtgct caagtgacta ttttagatat tagtgccaag cgtctctcag
      601 ttctagaaga agtctttgga agtcaaattc aaactcttat atctaattca ttcaacattg
      661 aagcaagtat gagagatgct gatgtggtga ttggagccat tctcatccct ggtgcaaaag
      721 caccggaatt ggtgacagat gagatggtca aacaaatgcg tccaggctct gtatcgttga
      781 cgttgctgtt gaccaaggtg gcgttatcga aacagctgac cgtgtgacaa cgcacgatga
      841 acccgtctat gaaaaacacg gtgttctcca ctatgccgtt gccaatatcc ctggtgcggt
      901 tgctcgcact tcaaccatcg ccctaaccaa tgtcactctt ccttatatcg aagctttggc
      961 tggcaaagga ttcgcacaag caatctctga agatgaaggc ttgcgtcaag gtgtgaccac
     1021 ttatcaaggt tacttgacta gcctaccagt tgctcaagga cttaatcgtg actacactga
     1081 tatcaatgat ttagtataaa ttttgaaaag aaaagggtga cttcgcaagt cctacccact
     1141 gtgctttgtg tcatcagcta ttacatcgtt ggtttattgt actgtatact ttgcaactgg
     1201 agactttcgt tccagactca attgtgcata agaaactcta aattgaataa agtcaacaga
     1261 gtttcgccca accacttcgt cttgtaatga caattatata aaccaaagga agctgagctc
     1321 tttagtccca gcttcttttt atatataaaa ttttacccgt gcaaagacag ggccttagca
     1381 gacttctttt ttacttcgtt cacccttgct ttttcttttt aggtttgggc gttggcagtt
     1441 ggttatacat agctaaaatc aggtcttata gaaacatctt attatcaagt tcttccactc
     1501 aaatcatttc tttggcacct ttgtatggaa actcaaaaaa agattggtca atcttatcta
     1561 agactgcttg cacgggttta actaaaaagc gatcatcata aatgccgcca ataatcttgc
     1621 cgcggaagta aagaatatac tcccccatca tggaacggta agtcacatca tctaatcctg
     1681 ataattgttc caaaacaaat tccaaatagt tcttacttga tgccatttct aatcttctag
     1741 gctctgttca gcgataacaa ccgtatagag ttcttgctta acctcgcatc caattgattt
     1801 aaagccctgc ttttcccaaa aatgctgaga ttgcggattt cccttaacat aagccaaacg
     1861 tgcctttcga aagttcttag caaaataagc tagtgcttct gtcacaatat gactaccaat
     1921 ccctttcctc tgataggctt gatcaaccat aaacaaacca ataaaaacag tctcctcatc
     1981 aggatgtgca tagacaaaat ctataacagc cacaaggtca gatccattcc aaaatccaac
     2041 aaaaaactta tcagccttag ctttaccttc aggtagacaa agcatgtcct cttttacagt
     2101 tgcaaaattt ggctctggtg gacaatgctg aaaatacaga ggattacttt catataaaga
     2161 taaaatactt ggaatatcct tttcagttag tatcctacaa ctgtaatact tagatagttg
     2221 gtcaatcatc ttttcaaatt cctactttct tgtgccctgt gattatgaca caggaagatg
     2281 cactgatcgt catcagccac ataaaagttc tttccatcgt gcctaatcgt tgtctcaaac
     2341 ctttggataa aacctttagc ctatacaact ggattttcct ctctcaaaag tatattcttt
     2401 tgcaggcaaa cttcctcaaa atcagtcgtg tgcaacttca gtagaatatt cataggctcg
     2461 gataatctga gcgacaactg gatggcgaac cacatccttg gctgaaaaat gaacaaagtc
     2521 aatctgatgg atgttcttga gtttctcttg agcatcaatc aaaccggact tgacattacg
     2581 tggcaggtca atctgactaa tatctccatt gacaatcatc ttagaatgaa aacctaaacg
     2641 agtcaagaac atcttcatct gcatgatggt cgtattttgc gcctcatcga gaatgacaaa
     2701 ggcatcatcc aaggtccgtc cacgcatata ggcaaggggc gcaatctcga taatttcacg
     2761 ctccatgagt cgagttgttt ggtctttccc cagaatctga tacaaggcat cgtaaacagg
     2821 acgaaggtaa ggatccacct tctccttaag atcacccgga agaaatccaa gactctctcc
     2881 cgcttccacc gctggacgag ttaggataat tcgcttgact tgcccacgtt taagggcagt
     2941 cactgccaag gtcactgcaa ggaaggtctt ccctgtacct gctggcccaa ttccaaaggt
     3001 cacatcatgc tgtttgacac tgtccacata aagcttttgc cctagggttt tgacacggat
     3061 aggtttccca gtattatctt tgataatttc ttcttcgtaa agggcgacaa acttgtcaat
     3121 ttcatcattt ttgaccatgc taatcgcagt gactacatct ggcgtaccaa cggtcatccc
     3181 acgatttacc aagaccatca aagcctgaat aacttgacgg gcttcctcac aggcagactc
     3241 ttctcccaaa acctggacaa tctccgtacg agcatgaatc acaacatcaa gctcttcttc
     3301 catcaaacga agatggcgtt cattggaacc aaaaagatga aacaggtcat ctggatgact
     3361 cagttgaatg tctattgaat gttccttcaa ataaagaacc tctctaatcc ttttatttct
     3421 ttttattata gcagagggat ggagaaatta ctagcccaaa cccaatgaat aaatgctagt
     3481 gttctagata ttcctgccaa atgctgtcaa aatctcctag gttaaaagag aaactggcat
     3541 gctcctccaa aaagcgactg acctcatcaa aatcatctgt atgttttgga aaagctgcct
     3601 cttcaaaagc gaggtctgcc aaaattgctt tgggactgtt acttttagga ttgcgctcgg
     3661 tcatgagcca agtgtaaaat gattttctca taagcctccc taaatcaact ctgtcccaaa
     3721 ctggtcctgc ttgattttac cagccttcat aagaccacct aaagctttct tgaactgacc
     3781 tttagaaatg ccaaaggttg ccttgatgtc gtctggagat gacttatcat ttaaggtcat
     3841 gaaaccgcca ttactttcca aataagtcaa aatcatctga gcatcgtttt ccaacatttc
     3901 aaaggagcgt ggtttgaggg agaggttcag agtgcggtcc acttcacgga aaccaataac
     3961 gcgcgcatct aatacttgcc ccaaacgtgg ctctgcgtaa cgctcgctag gatgaataaa
     4021 accaagcata ttattttctg gtaggtaaac aaaagttcct gacagcttga gacggtaaac
     4081 aatggctggc cagttttggt tctgcatgtt gttgtaggca ggacgagcaa gacgttggaa
     4141 gtcttcttga taagccaaga ggccccagat acggtctttc ttatccactt caagacggat
     4201 gtagagttgg tcgcccttct taggccagag ttccttgagc tcagggagaa tatcgagtga
     4261 cacaacgatt tccttgtcag gaaggcctgt atctacaaag acacccaagt ccttacgaac
     4321 ctctgtgaca catccccaac caaattggtc ctgagtggca gtcacttcta aggttgtcag
     4381 gcggagtttt tgcttcatat ccgtgtatgc aaaacctttg accgtatccc ctactgtatg
     4441 ttggccctct tccttagcaa gagcataggt ttgaccatcc ttttgcacaa agtaaaaacg
     4501 gtcattttca tcgatgatca gtccaacgat aaaacttgca agatttgtat tcatatttcc
     4561 ttctttcgaa taaaactcag ccagcaatgc caactgagtt tttctgttta tttttagact
     4621 tccaaaagtt ctttctcttt gttagcagtc atgtcgtcga tgtgtttaac agcatcgtct
     4681 gttacttttt gaatatcttt ttcaagagtc ttcaattcgt cttcagtgat ttcttttgct
     4741 ttttcttgtt tcttagcttc gtccatagca tcgcgacgga tattgcggac agccacttta
     4801 gcattttcgc cgaccttctt cacttcttta gcaaggtcac gacgagtttc ttctgtaaga
     4861 gctgggataa ccaagcgaat cacagaaccg tcattagccg gtgtgatacc aagatcagaa
     4921 gcgttcaagg cacgttcgat gtctttcaat gaagacttgt caaatggtgt taccaacaaa
     4981 acacgcgctt ctggaatcgt aattgaagcg atttggttaa gaggagtttc gactccatag
     5041 tattctacat gtacacggtc aagcaagctt gcattggcac gaccagcacg gataccacca
     5101 aattcacgag caagtgattg gtgagattgg gtcattctct ctttagcttt ttcaataatt
     5161 acgttagcca tattctttct tattcctttt cttcgatatt atttgaaact gttgttccga
     5221 tattttcacc aaatacgaca cgtttgatgt tgcctgattg gttcatgttg aagacaacca
     5281 agtcaatgtc gttgtccatt gagagggttg aggctgttga gtccatgata cgaagacctt
     5341 tgttgataac atcacggtgg gtcaattctt caaacttaac ggctgtcttg tccttcttag
     5401 gatcggcatt gtacacacca tcgacgccat ttttagccat gaggatggca tctgcttcga
     5461 tttcagctgc acgaagggcc gctgttgtat ctgtcgagaa gtatggtgaa ccaattccag
     5521 caccaaagat aacgatacgg cctttttcaa ggtgacgaag ggcacgtcca cggacataag
     5581 gctctgccac ttgttgcata gcaatagctg tttgtacacg cgtatcaacc ccaacttgtt
     5641 gcaatgaatc tgccatcaca agagcattca taacagtccc aagcattcca gtgtaatctg
     5701 cctgaacacg gtccatacct gcttctgctg caggttctcc acgccaaaga tttcctccac
     5761 caataacaag ggcaatttcg atacctaagc tatgaacttc ttgaatctct tttgcgattg
     5821 tttgaactgt ttggatatca atccctacgc cacgttcacc ggcaagggct tcacctgata
     5881 acttgattaa aatacgttta tacttgggat tcgccatttt cactctcctt ctttcatcct
     5941 acctatttta tcacaatttc taagattttt atagtatcat gagcaattct ttcaaaaaaa
     6001 ttagacagtc aaaaattcct ctaagtcggc aagggcacgc tctgcaattt tttcataacg
     6061 agccttctta tcacggatac gctcgccttc caactccttg atgatcccaa aattgacatt
     6121 cattggttgg aaatgtttgc tgtcggcatg ggtaatgtaa tgagctaagc ttccaatcgc
     6181 tgtcgtctcg gggaaaataa cctcgctttc ttccttgaag agacgagctg cgttaattcc
     6241 cgcaactaag cccgaagccg ccgactcaac atagccttcc acccccgtca tctgaccagc
     6301 aaagaagaga tttggttgtt tcttggaacg gtaagtctgc tcaagaagat ttggtgaatc
     6361 catgtaagaa ttgcgatgca tgacaccata acggacaaac tccgcatttt caagacccgg
     6421 aatcatttgg aagacacgct tttgttctcc ccatttgagg tgggtctgga aaccaacaat
     6481 attgtagagg ctaccagctg cattatcctg acgaagttgc acaaccgcat aaggtgtttt
     6541 aaattctcca tcacgaggtc ctgtgtagtc gtccggatac tcaagaccga ctggcttcat
     6601 agggccataa agcatagttt taatgccacg tttggccata acttcgattg gcatacatcc
     6661 ttcaaagtac ttttcttttt caaaagaatt gagcggtgct tcttccgcat tgaccaaggc
     6721 ttcatggaaa tccataaact cttgcttggt cattggagca ttgagatagg ctgcttctcc
     6781 cttatcataa cgagatttga gatagacctt actcatatcg atagtgttga catcgataat
     6841 aggcgctgct gcatcgtaga aatagaagcc atcgccatta ttaagggcat gaatcttttc
     6901 agccagggca tcgctagtca agggaccagt cgccacaact gtaataacat ctgttggcaa
     6961 ttctgtaatt tcatcacgca ccacttcaat caaggggtgg ttgaccactt tttcggtcac
     7021 catttgagag aaaccatcac gatccaccgc aagggctcca ccggcaggaa cacgtgtagc
     7081 ctcagcagat tccaagataa cagaacccaa gcgacgcatt tcttccttga gaagaccaac
     7141 tgcatttgtc aaagcatccc cacgcaaaga attggaacaa accaactcag caaaattgtc
     7201 tgttttgtgc tgaggagtcg acttgacacc acgcatttca taaagtttaa ctggaatacc
     7261 acgctctgcg atttggtagg ctgcttcaga acctgccaaa ccagcaccga taacattgat
     7321 ataagattga gacacgacac taatacctct ttgggagtgt gaagttaaga ttcacattga
     7381 aaaagccaat cagacttacg agatttcgag tttcttggct caggctgaaa aagtccccca
     7441 gactttcctc gctctcgaat ttcttggctc aagctgaaaa agtcccccgg actttttcac
     7501 tcccacaaat ctttctattt ttttcttcta ctagtataac aaaaaaaggg aagaaggcaa
     7561 acttccctgt ttagtcattt tcttgatgta aagagataga gagtattcca gttaagaatc
     7621 aattatatgc tactctataa aatcttttcc acataacgga tcgataggga ctgttattct
     7681 atctcttgct ataaccgtat tatctaaaac agcataacat tcaacatagt gatctccttt
     7741 aaactgtgaa tcttcgtgat attttatttt acctgaaaaa atagcaccac gctcacaatt
     7801 tcttctaata gcctcagctt caatatttct tactttccaa tagacttcct gcgaaacaaa
     7861 atatggtata gtagttctat gaatgatgaa gcaagtaaac aactaactga tgcacgattt
     7921 aagcgtcttg ttggtgttca gcgcacgact tttgaagaga tattagctgt attaaaaaca
     7981 gcttatcaac ttaaacacgc aaaaggtgga cgaaaaccta aattaagcct agaagacctt
     8041 cttatggcca ctcttcaata tgtgcgagaa tatcgaactt atgaacaaat tgcggctgat
     8101 tttggtattc acgaaagcaa cttaatccgt cggagccaat gggttgaagt aactcttgtt
     8161 caaagtggtg ttacgatttc aagaactcct ctcagttctg aggacacggt aatgattgat
     8221 gcgacggaag taaaaatcaa tcgccctaaa aaaacaatta gcgaatcatt ctggtaaaaa
     8281 gaaatttcac gctatgaagg ctcaagcgat tgtcacaagt caagggagaa ttgtttcttt
     8341 ggatatcgct gtgaactatt gtcgtgatat gaagttgttc aaaatgagtc gcagaaatat
     8401 cggacaagct ggtaaaatct tgtctgacag tggttatcaa gggctcatga agatatatcc
     8461 tcaagtacaa actccacgta aatccagcaa actcaagccg ctaacagctg aagataaagc
     8521 ctgtaaccat gcgctatcca aggagagaag caagattgag aacatctttg ccaaagtaaa
     8581 aacgtttaaa atgttttcaa caatctatcg aaatcatcgt aaacgcttcg gattacgaat
     8641 gaatttgatt gctggcatta tcaatcatga actaggattc tagttttgca ggaagtctaa
     8701 tgtaattctc aagctgtgag ttcattatga tttgtaaatc cgatatatct tcagcagcta
     8761 aaaacacatt ttgaaatgtt ccaagtccgt tttcaccaaa actatattct ctcttactat
     8821 acttactctt attattctct atatagttag agtcaaggtt cttaacctct tgaagttcat
     8881 tttctttact tctgaggtta aaatctttta cttctgaagt taagtttttt gacttctgta
     8941 agtcattttc ttttacctga aatatactca taaagtcttt aacataaatg atgttcggct
     9001 taccaagtcc aagccttact ctttcgatca gtcctattcc ttttttacat caagctcatc
     9061 taatgttttt atggcagttg gctttgagat atttcttctt ttcataattt cttcgacagt
     9121 aaaatagata aatactctgc cttccttgtc tatccagtta ttcttaaatg acattcctgt
     9181 ctgtttaaga agtatggaat aaaggataat tgcttctgct gataagcccc gaaattcttc
     9241 tctatcaact aatatctccg gtacttttaa gaagttaaat ctttccgctt ctctgttata
     9301 aaaatattca aagtccatgc aagatcacct cccttcttaa aaatttgcaa agaaaaagac
     9361 gatagttttt cttctatcgc ctttggtaac catttttatg aaatttttta aagttaaaaa
     9421 tataatttat aatactatct tcttccattt tctgatttta gttctgaaag ttccaaaagg
     9481 tgcaaccgta tttacatgaa taaacttata cacttcccaa gtcgctgttt tagtcgcttc
     9541 atcagcccac tttctcatat gcggttcaaa taattcttcc tcactcaacg aatcaatcat
     9601 tgcagagata gaattaatat tttcatttaa ttttgctttc aactcttgca gagataaatg
     9661 agcgtaggta tctgtgaacc actgatataa ttcaccaagt tgattccatt taaatttatc
     9721 cgatggtgtt tttacttgaa gcccctttct ttcatcttct tcccatttaa gaaccaagtt
     9781 ggtccaacca acctgataag caaggttttc tgctggagtt ctgtcaactt catcagctct
     9841 cttatctttt aaattttctg gaatattatc aaattctaaa atatatttct caaatgtttt
     9901 ctctatctca gcttttagtt cttctttatt ttcgtatgtt cgcaaaaaat caccttcttt
     9961 ctgatttatc aatcctttga tttaaaatga ccttattttt ctatttatac cttctaagaa
    10021 cgctataact gctgctccaa ccatcggtat tccgtatggg cttaataaaa aacttaatac
    10081 caaagcttct ataccaagtg atacatcttt atattatcat cactaattaa gttaaacaga
    10141 aacagacaga attattacat cctgtctccc tttattgttt ttcttcccag tcgtggtagg
    10201 cagcgtagag ctgactttta ttccactggt aaatcttagc gacttccttg atagcttggt
    10261 ttttcttcac accttgctgg atgcgggttt gaatttctac gaacaagtct tcctcgtcct
    10321 tttcctccac accctgactg gcaccctcaa caatgagaag acattcgccc ttgagtggcg
    10381 tttcagcaat gctttctaat aactcagaga tagtacctcg ttggtattct tcatagattt
    10441 tggtcaattc cctgaccaag acaacggagc ggtcaccgta gacttctaac atattttcca
    10501 acgtgtctgc tacacgatga ggtgattcat aaaaaatctg tgtttcagga taatcttttt
    10561 tcaagccaaa aaattgcttc tgctgacctg attttctcgg taaaaaaccg taaaagatat
    10621 gtggctgtgg cgctaaacca ctggcaatca aggcagaaat tcctgcagag gcacctggaa
    10681 ctgtcacaac tgcaatttct tcctcaatag ctgccttaac taaatcatga ccagggtctg
    10741 aaatgctagg caaaccggca tcagagacct gagcaatact ttgccctgct ttcaagaaac
    10801 caatcaaatc aggaattttt tccttggcat tgtgctcatg aaaactgatc tgcttggtgg
    10861 aaatgtcaaa atgcttgagc aaaagccctg tattgcgcgt atcctcagca gcaatccagt
    10921 ccacttcttt caaggtctgg atagcacgaa aagtcatatc atctagattg ccaatcggcg
    10981 ttgccactag atacagcttg ccatagggag actgcccctt aaaacttttt tgaatttgca
    11041 tgcttactcc ctgtataaca actcatcaca gaacatacat tcttcgtcct gctctcgacg
    11101 ttgtccataa aaatcattac atacgtgaaa tccatcacgg taaatacgac ggacactttc
    11161 gcgaacatgc ttggccttga cgggagcgtc tgcttccacc tcacccaagc gttctcgcaa
    11221 cttactattt tccaagcgaa gagctgtatt ttcttctacc aagctcttga gatttttctt
    11281 gatggcttcc acatcggcta aggttaccaa taattgttgg gaaaaatcat ccagcgcgtc
    11341 aaataattct tttttgtcca taaaacagcc ctttcctttc tttatcattc atttttgagt
    11401 ttatatttct ttcaagacca gatattccat ggcattttga aagctgacat tagcttgcca
    11461 catttttcta gcttctagta aatcttgtag aatcactctt actcttacct gcaagaggtc
    11521 ctgcccacag agaacttcaa gaatccgtaa aacctgatcc tgtttttcct tatcatctgc
    11581 caagttggct aatttggcaa cctgtagata actttctttt ttcttagcta ctaaccaagt
    11641 cagcaggcgt tcactttcat cgaccaaggt ccaaaaactt gcctgattag ccaacttttc
    11701 tgcttcagct cgcgattgac taaacttagc taaaagagtc gcttttttct taacaagtcc
    11761 catttgttct aagagtaaga taagtttttc ttcttgcttt ttaaagtgga agatctgagt
    11821 ccgacttcgg attgtcggta acatcttttc ctcatcgcta gtcaagaaga aaatataaac
    11881 ttcactctgg ggttcttcga tgaccttgag cagagaattg gctgcgttgg gatgcatttt
    11941 atccgcttgc tcgataataa agacctgttg ctggctttca atccctgctt gagaaaactg
    12001 tcccaccaat tcccgaatgc gttctgtctt gatgacctga ttgactggct taatcaaggt
    12061 gacatctgga aactcttcct gttcaatcag cttgcaactt cggcatttct cacatggtaa
    12121 gacgccaact ttatccgtac aaaagaggct cttagctaaa aattgcgcca tttccaagct
    12181 tccaaagaaa cctgaaaaga gataggcgtg attgagctgg tcttgttcta agatacggac
    12241 aaaacggtca aactgagctg gttgccaagc ctttagttga tcttgtttca tttggccaag
    12301 tccattccgt caaacaagac agccttggta gtttccacaa cttgctccaa agggagacta
    12361 gcatcaatct tgacaatgcg atttccttct ttttccagga gagaaaggta gccttgacgg
    12421 actttcttgt gcaattccaa accttccaag tccagacgat tgacctcgcg gtcactattc
    12481 gcagcaatgc gagccagccc ttcttccacc tcgatgtcaa aatagagtgt caaatcgggt
    12541 ttgaggccat ctgtcgcaaa ctgattgagc cagtcaatgg cttcaatatc taagccacga
    12601 ccaaatccct gataggcaac agaactatcg ataaaacgat ccatgatgac caacttgcca
    12661 gcttcaaggg ctggaagaac tttttccacc aaatgctgtc tgcgactggc aatatagaga
    12721 agtagctctg ttttagcatc catctgagta tgacttggat ccaaaatcac ttcccgaatc
    12781 ttctccccaa tcaagactcc gccaggttca cgggtcgtca gcacctttac tcctttttcc
    12841 tctaaaattg gtagcagagc ctctaaaaca ctggtcttgc ctgctccctc tggtccctca
    12901 agagagacta aaaatccttt tgacatgtct aactcatttc ttttttacta cttctattct
    12961 atcaaaaaaa taggggtttg tgacaatctt tttgtcttct catttcatac tcaatgaaaa
    13021 tcaaagagca aactaggaag ctagccgcag gctgtacttg agtacggcaa ggtgaagctg
    13081 acgcagtttg aatttgattt tcgaagagta tcaaccacca taaaagaggc agataaaact
    13141 acctcttatt tacctagttc ttgtgttcgt ttgtaggctt gatgaactgc atccatgact
    13201 gttcctcgga aagcatgcgc ttctaggctt gctacaccag cgatagtcga accgcctggg
    13261 ctacagactt ggtctttcaa tactccagga tgttgctgac tttcaaggac caattgccca
    13321 gctcctacca cagtttgtgc tgccattttc aatgctattt ctcgtggtaa tcctgtctga
    13381 acacctgcat ctgccaaggc ctcgataaaa agatagacaa aggctggtcc acaacctgca
    13441 agacctgtcg ctgcatcgat taaactttct cctagttcaa ccaagagacc agccttggct
    13501 aaaagctgat aaaagagctc actgtcctca gccctgcaat taggagacaa ggcataacta
    13561 atcactcctt gcccgataga agcaggggta ttaggcatca tacgaataat tcggtgttga
    13621 cttgggataa gacttgctag tttttctaag gtcaatccag ctgccatcga aatcaaaaga
    13681 agactttctc ttttttcaag gatggtctgg tattgagaaa gcagttcaga aaactgagca
    13741 ggcttaactc ctagaaaaat cacatctgct tctgcaaaca tttcttcatt gctggaagcc
    13801 tgaccaccaa agtctgcaat gaaagcatct accttagctt gactacgatt ggcaaggaga
    13861 atctcatctg acgtcctagt ctgcaagaca gattttgcca agctagcacc catattcccc
    13921 aaaccgataa atccaatctt catctcttac tcccttatct gcccatcacc ggcaaccaca
    13981 tacttgtagc tggtcaactc tttcaagccc atgggaccac gcgcgtgcaa tttctgagta
    14041 gaaatcccca tttcacaacc aagaccaaat tgtcctccat ctgtgaaacg agttgaggca
    14101 ttaacataca ccgctgcaga gtccacttga tctgtaaagt atgctgcagc ttcagcattt
    14161 tccgtcacaa tagcatccga atgatgggtg ctgtgggatt caatgtgcgc aaccgcttct
    14221 tctaaactgc tcacaacctt aacagcaagg acatagtcta aaaactcggt gtcaaagtct
    14281 tgggtctcag ctgcttgacc tgaaacaaac tggcttgctt tgctatccaa gcggaattga
    14341 attggttcca gtccagcttc cttacgctct gcaaccagca tttgatccaa gcgaggaagg
    14401 atgcttgctg ccttgttttc atgaaccagc agaacctcca tggcattaca aacagaagga
    14461 cgactggttt tagcattgtt gatgatagac agcgccttgt cttcgtctgc atccttatcc
    14521 acatagacat ggacaatccc agtccctgtc tcgataacag gtacaatcgc attctcaacc
    14581 actgcattga tcaagccagc tcctccacga ggaatgagaa ggtctagata gcccttggcc
    14641 ttcatcatag cataactact ttcacggcta gtatcctcca ccagttgaat cacatttgga
    14701 tgaatagtag tcgtctccaa gcccttcttc aaggctgtga caatggcatg ggttgtttga
    14761 taggcatcct taccactacg aagaacaacc gcatttccac tcttaagagt caaagcagcc
    14821 gcatcagacg tcacatttgg acggctttca tagataatac cgatgacacc tatagctaca
    14881 cgtttttttg tgataaccaa accattttca agctgacttg tttctaaaac ttcaccgatt
    14941 ggatctggta aggcaaccac ttcacgaatt cctcttgcca tcgcttctat acgatctgca
    15001 tccaaataaa gacgatccaa catcacatct gagattttcc ccttagccgc tgccatatcg
    15061 agggcattag ccgctaaaat ttcctcagta gcagccacta agtgatcagc catggctagc
    15121 aaggcttggt ttttcacttc ttcactagct gtgttaatcg attttttaac agcctgtacc
    15181 tgttcaaatt gttcttgtct actcaccata gtttacctct aaaattctgt aaaaagtagt
    15241 tggatttcag gagtaatgga aatccagtcg tcacggtaaa tcaagacacc cttggctttt
    15301 tgagaacgca acatatcctc caaagcagat gctccaaatt gcacgcgtcc ttttccaagt
    15361 gattttccac tttccttgtc aaatactgtc acgatatcac cgtaagaaaa ggctccttct
    15421 gcttcaacga taccagataa gagaagactc tttccatgtt gagagagagc ttccgcagcc
    15481 cctttatcaa cccaaataga accttgactc tgagcataga aggcaagcca ttgtttctgg
    15541 gtacgaagcc ccttctcttg agcaacaaag taagaaccat cctcggtctc ctctgccgcc
    15601 tcaatcatgg aatctgattt caaggatgag cagatataaa caggaactcc tgattccgtc
    15661 gcgatagttg cagccttgat tttggttaac atacccccag ttccgtttga cgaaccagct
    15721 ccaccagcca tatcaataat ctcacgattg atggtctcga ttctctccaa gcgtttggct
    15781 cttggatctg aattaggatt tccagtatag agaccgtcca catctgtcaa gaaaactaaa
    15841 aggtctgctt ggaccatcgc cgctacttga gcacttagag tgtcattgtc cccaaccttg
    15901 agctcatcaa taacgacact atcattctca ttgatgatag gaattgcccc acggttgagc
    15961 aaaaccgaca aagcctgatg ggcattttta taacgacgct tatccacaaa gtcatcttgg
    16021 gtcagcaaga tttgtgcaga aacgatttga cgcaagagaa gattggtcgt atattcttcc
    16081 aacaaaagtc cctgccctac cgctgctgaa gcctgtttat cagcaatttt agtcggacgc
    16141 tttttaaatc ctaaggctcc aaaaccagcc gcaatggcac ctgaagacac caaaatcaac
    16201 tcatgaccag cctcgtgcag catagccaac tgctgggtaa tatcctttac cttactacgt
    16261 gataaacttc catcctcatt tgtcagagaa gaagtaccca ccttaaagac aatccgtttg
    16321 tatttcatag tctcactccg attattcata tttatccatt ataacatgaa taacaggaaa
    16381 tagaaaagag ttgataggaa aaagaaggcc ctaaaacctt cttttctact actgttctga
    16441 ttccgatttg tttacactcg tttcagagct ttgtgaagtt gaggatgtca aatcttgact
    16501 agttgaaaaa tttgtaacac tttcatgttg actcgtttct ttattttcaa gatccttttt
    16561 cactacttct ttggattctt ttatttctga atgacttgta gttttaattg tagcagattt
    16621 ctcgatcgaa acatccacta accaggcacc acttgaatcc acagtataac cttctggtgt
    16681 cttaccgttc acaagtaatt gaccattttc tttcaagaag taccatttat ccttgtcctt
    16741 gatccaaccc acagctcgtg aaccgtctgt cttgtagaaa taccaatcat ttgccttttt
    16801 atgccagcct tgcttcatag ctcctgaatc ttccagataa taatgttgac cagcaacttc
    16861 tatctcacct gtcttcatga caccagtaga atccatatag taccaggttt ctttatcttt
    16921 tacccagccc attttcattt cccctgatgg agcaaagtaa taccattgcc ccatatattg
    16981 aagccatcct gtcttcatag aaccatcaac atccaaataa taccactgct ctttatcttg
    17041 aatccaacca atttccatct ggttttcttt gttaaaataa taccagattc cagcgatttt
    17101 cttccaattt ttagcagaag caccagagtc tgtcaaatag aaccaatgat tgttccattt
    17161 tttccattga ttctgtaaca agatacccgt ttggttaaag taataccatt caccttcgat
    17221 ttcattccaa ccgacagcat actctcctgt agaatcaggc gcttgatacc accagttccc
    17281 atatgcactc ttatgccaac cagcttgaaa acttggaatc ggcttgtagg atgttgaaat
    17341 attgacaaaa ccgtcttttc gaatatcaaa aactgttgca tcatagtctt tgctggctgc
    17401 gttgattctc tcaattcctc gttctttgag ccaattaaca tactcactat caacaccatt
    17461 tttccaaggt agactatccg aagtttgaac aatcaaactc ggactcaaat ttttaatgaa
    17521 atccttggta tttgatttgt tggtatcatg gtgatgatta aacttcatca aatcaacttt
    17581 tccaatgaga ggaccatact tgtcttctgc tccatgaaca ttatctaaat cgcccccaag
    17641 gtaaattttc ttgccattga ctttcaccac gctaatcaag gaattggaat tgtcatccca
    17701 aattttcttt aattcacccg atgaatcagt ttcattttca taattataga gctgaatatc
    17761 catgtcccca aactgaaaat gagcatcccc ttgtgtgata ttttgaataa ctgaaacacc
    17821 tttttctgca gcagtctgta aaaccttatc atagccatac agattatccc atagacgttc
    17881 agaattagta atacgactat cactatattt cttaagatag actcggtcaa ctggataggt
    17941 agacagtaat tcatcaacat ttccaatatg atcactgtgg gtatgggtca ccaaaataaa
    18001 atcaagtttt tggacaccca attccttcaa acgacgaaag acacggtctg ttagaacatg
    18061 cttataagac gtttcaattc cttctctcca tggatagcga gaatcacttc catctgggaa
    18121 atcataatct tctcctgtat ccaccatggc aaaatgtcca ttgctttcaa gaataatcgc
    18181 atcactgcca ccttcttgaa cattgataaa gtggatttta tttcctgaac tttcttgagc
    18241 ctgaacattc ccataccatg acaaacctaa aaaagcgcct acaagtgcta aactagttaa
    18301 tttctttttc attcttactt tctcaatctc tccaaggttt ccttaaaaat ctctgggata
    18361 tctgctttaa attccaaggt cttacctgtt ctcggatgag taaaacctaa agtcttggca
    18421 tgaagaaatt gtccatgtcc tttcaaagtc ttgcgaggac catagacctc atcaccagcg
    18481 actggatggc cgatataagc catgtggaca cggatttgat gagtgcgccc tgtctccagt
    18541 tgcaactcta ctaagctata atcgccaaag cgttccaaga cgtgaaaacg cgtcactgca
    18601 ggcttccctt tagcagttac agcctgtttc ttacggtctt tttcactccg gccaatcggc
    18661 gcttcaatta caccacgatc attaggtaga tttccatgaa caatcgccca atatttgcgg
    18721 agagactttt tatccttgag ttcttgggca agtgctagat gcgcatcatc gtttttagca
    18781 atcatgagaa gacctgacgt atccttatca atacggtgaa caatccctgg acgcagaacc
    18841 ccattgatac ccgacaagtc cttaatatga tacatgaggg catttactag ggttccactg
    18901 gtatgaccag cactcgggtg cacaaccatt ccctgaggtt tgttaacgac agccacatcc
    18961 tcatcttggt agactatttc tagcggaaga tcctcagcca catactctaa tacctctggt
    19021 tctggcacat ggtaagtgac gacatcaccc tcttggactg tgtatttagc tttcttgact
    19081 tgaccattga ccaagacctg gcctgattta atttgttcat tcgcgagact acgtgataat
    19141 tctgacaaat ctgacaaagc cttatccaaa cgcagaccac cagtttcaat tttaatttcc
    19201 atttatttcc tcttttagca ttgcaatcaa taaaataatc actccaaccg tcagatagct
    19261 atctgccaca ttgaaaattg caaagttgat aaagtcaagg tggaacatat ccacaacaaa
    19321 gccctgactg accctgtcaa taaagtttcc aagaccaccc gcgattatta gagtcaaacc
    19381 caagaccatc cagaatgagt cctccatgtg tttatgtaaa taccaaatgg cacctatcac
    19441 gacaaccaga gtaatgacag cgaataacaa ctgctgatct tgtaagatag aaaaggctgc
    19501 acctcgattt tgcaggtagg tcaagctaac gaaattgggg atccaggagc gcacttcacc
    19561 cagtggaatc tgctggacga tataggattt gaccaactga tccagcccaa tcaaaagcag
    19621 tacaatgact gccactattg ctcttttttt catgatttcc tcttttgatc aaaatattct
    19681 tgcatgactt ctacgaagag agtcccagct tgactaagct ccacttcttc acgtttaaca
    19741 tagaccatgc ggttatctag gttatccttg agacgaataa ctgtaatgcc attaacactg
    19801 tcactatcta aaaatccaga acctgtcgca taggcgtccg tccgctccaa aataccattc
    19861 aaggtggcac ggtctgtcac attaaacatc tgtgagctag cgctggtatc aacaaagttc
    19921 tctgaataat aaaggtactc gtctttctct tgagtgaaac gaaccgttgg taaatccgct
    19981 aaatcctcca tgactaattc ctctttctgg gctaaaggat gaccctcaca gagataaata
    20041 tgggtatgga aaggaatcaa ttcgatgacc tccagaccta acttttcaac ccgttgcata
    20101 atcccctttt tattttgatt gttgaggtag ataatcccaa tctcactatg cccttgcgcc
    20161 acttcatcta atatttgaac agtagttgat tcaaaaatac ggaagttctt atagtcagga
    20221 tagcgctctg aaaaggccgt aatagttggt ggtaagaagt catagtgctg gctagcaacg
    20281 gaaaattcat ctttttcttc ttcaggattg gcatactgat tttgaaaaat atcaaatcct
    20341 ttaaccaatt cttgcgcttt ttcataaaat tccatcccac gacgggtcaa gaaagtccct
    20401 gagctggtcc gacggaaaat cttaaaaccc aactcttttt ccaaatcccg aacagaaata
    20461 gacagactcg gctgactaac atacatcttt tcagcagctt cacgaaaagt accactattg
    20521 gcaatagcca caacatagcg taattgttga atgttcatct tctaccccta acttctttat
    20581 cttttcatta taccatattt tagaagtttt ccaaaaagga aaaaagaaca tcctattctt
    20641 cttaactatc ttcactatct gcctttctca cgccaatctt attttcaaaa tcaattcaaa
    20701 aaaataagtg gctacacacc acttcagtat cggaaagaaa aacgttgact atttgtgaaa
    20761 aaagaaaatg ccggaaaatt ccgacatttt tttagtaagc taacttcctg aaaataggag
    20821 taaccaaaca tcccagaagg cagtgatatt gatgagaata tgaactagta ttggatagta
    20881 gagattttta gtcatgcgat acaatagagc taaaatcaga cctccactag cataaatgaa
    20941 aaaagcaaga ggagttaaag caaaattgat atgaatataa ccgaaaataa tagcagaaag
    21001 caaaacatct ccgtaccaag gtgagttttt gaaaaaggtt gtcataagca cacctcgata
    21061 aatcaattcc tcagcaatag gggcgatgaa gcaaacgatg agcaagaaat aagggaactc
    21121 ctgtctcccc atcatttcta tcgtttcatt caaagaaatc tgatttgaag acagggatat
    21181 gaaatacgaa aagaggaagt cagacatata tgaaatgatg tagcccagta aaaggtagat
    21241 gaagtacctc agctgccact tgaaatgaaa aattttcttt cctgcaaaaa ccagtagata
    21301 gatgaccgct aagaaaagaa ctccgctctc catcaaaagc agaatctgaa aaaattcacg
    21361 acttgctggt agatagggct ttgcgaggtg attgaaaact ctccaaaacc aagttgattt
    21421 gtaaaaaatt aaggacaatg ctagtaaaat ttgaatagcc cgttttttca tattaaattc
    21481 tctgctttct ccccttgttt cttcatatta ctaataaatt ttacttaaaa tctcgcagca
    21541 cttcctttgc aaagatgatt gcctcctcca atatatccta aatcataggt gcctctggga
    21601 caaaatccat gaaccggcag agttaatact ggttctattt cccaatcgta cctaccatta
    21661 ggatttttac catatgaatc tgctccacct tgtatcagct ctaattcttc atttgttaga
    21721 tttatatttt ttgtcattaa aatcatgata tatttcctcc attattcttc agattagttg
    21781 agtaatctga tactcatacc tacttacaaa aaaactatta tattaagttg gttttttaat
    21841 ttgtctagtt gcaacattga caaacatagt atagcatatc tttgcgaaat atcctcttca
    21901 aatcatgaat tgtcatcaaa acatcttaaa ctataaaatc aattagtctc aagctttcta
    21961 tcaatttctt ctccaaaata tgctataata atagcaaaag ataaagaagg aagacctatg
    22021 attaaactac tagccttgga tatggacggc accctcctca atgaagccaa ggaaatccca
    22081 caagctcaca ttactgctat tcacaaagcc attgaaaaag gtgtcaaact ggttctctgt
    22141 acgggtcgcc cccttttcgg tgtcctcccc tactacaaaa aactgggact cgacctccag
    22201 aatgagtatg tgattgttaa caacggttgt tcaactcacc agactagcga ctggggcttg
    22261 gttgactggc aagaacttag tccagctgac atcgaatacc tctatgacct tgctgaaaag
    22321 agtgatgttc agttgacact ttttgacgag tcacattatt ttgttctcgg tggaaagccc
    22381 aatcaagtta ttgaaaatga tgctaaacta gtattttcag acctgactga aatttctctt
    22441 gaggaagcga ctagtggaaa gttccggatg ttccaaggta tgtttttagg aacaaaagaa
    22501 caaacagacg attttgagca gcgttttgct gaagagcttt gccaacgatt cagtggagtt
    22561 cgttcgcagc ctgtcattta tgaagcaatg ccacttggaa cgacaaaggc tactgctctt
    22621 tcacgactag ctgagatttt gaagattgat tcctcagaga ttatggccat gggcgatgct
    22681 aataacgata tcgaaatgct ccagtttgca gggcttggga ttgcaatggg aaatgccagc
    22741 gattatgtca aatctcttgc ggatgccgtt acctcaagca acgaagaaga cggcgttgcg
    22801 cgtgctattg agaaatatat tctataaaaa agaaaagcaa atagacagaa gttactgcta
    22861 tttgcttttt tgctaatatt ttaaaatacg gactaatcaa tagagaagaa tagcgaatca
    22921 taaaaatcga tttactagat gccatagtat cttatagttg ctaataagaa gttagtctag
    22981 cagaatgaat ctctcatttc tcccacacta atctgtaatt tgtctataca tttctggtct
    23041 tctatctcga aacaagcccc agtttaggcg ttcacttgct cccttgtcta ggttataagt
    23101 agctaacaga acagcttctt cttgtctttc agctcgttct agaatagctc ctgtttcatc
    23161 cgtcataaag gaggaaccgt agaagtcaag actggaactc tgtccgccat tttcctcact
    23221 aggagtaacc tcctctaaac cataacgatt ggctgcgatg actggaacaa tattcgctgc
    23281 tgcgtgccct tgcatagtac gttgccagtg accacaacta tctgtatcca aaatcggctc
    23341 tgaaccgatg gctgttggat aaaagagcaa ttcagcacca ttcaatgcaa gacagcgcgc
    23401 tgtttcaggg aaccattgat cccaacagat accgatacca atcttagcat agcgagtatt
    23461 ccagaccttg aaaccagtgt taccaggcgt gaaatagaat ttttcttgat aataatggtc
    23521 atctggtatg tgggtctttc gataaacgcc cagcacttcc ccatctgcat caatgacggc
    23581 aatagagtta tacaagacat taccatcttt ttcatagaaa ctgattggta aaacaacttg
    23641 tagttcctta gcaatcacct taaaatgctg aatggcagta ttttccgcta cagattgggc
    23701 atactggtag tagtcatact gacgttcctg acagaaatag ggatgttcaa acaactcggg
    23761 caagagaata atttgggctc cttgctcagc agcctgacgt actaaacgct ctgcggtttg
    23821 gatatttgtt gccacatcct tagcgcattg catctgaatg gttgcaactc ttacatttct
    23881 catctttttc tcctattctg gaatttgttg ggtgatacag tggatattgc caccacctaa
    23941 gagaatatct ctggctggta ttccgacaac tttacggtct gggaaacact tgctgaggat
    24001 atctaaggcc acttggtcgt ttacatcctc aaactgtgga accaagacag ccttgttggc
    24061 gatataaaag tttacgtagg aagctgctag tcgttcacct gcgtatcgct tttcttctcc
    24121 ttcttcatag atgtagcctg gcaaatcttc ttctgtcaca acttgtcgaa ctgcagggat
    24181 aggcaattta tgaatggtga agtgacaacc ttttgcatct gtttcctgtt ctaagagttc
    24241 gagatctgct tttgacatgg catactgggg atcattttcg tcatctgtcc aagccaaaac
    24301 aagctcagca ggaccaacaa aggcagcaac attatcgacg tgttcattgg tttcatcctg
    24361 ataaatacca taaggaagcc aaataacttt ttcagcacca agactttcta ataatgtgtt
    24421 ttcaatctcc tctttagtca ggttaggatt gcgaccagga ctaagcaagc aactttcagt
    24481 tacgagaata gttccttgac catcgctatg gattgcgcct ccttccagta caaaaggttt
    24541 agcatcatag acaggccttt ccaaggcctc agcaaaacga ctggctactt ggtcatcctc
    24601 ttcataatct tgataaagac catcataggt gcctccccaa gcattaaagg cccaatccac
    24661 ggctaatttc ttacctttat cattgacgag aatggttggg ccagtatcac gcgcccaggc
    24721 atcattggtg ggaatgtcta aataaacaac cttgtctcca agataggatt gggcttcaga
    24781 tagataggcc tgctccacca aaagatagac tctttcccct tctgctatgg tctcgatgat
    24841 ctgagtaaat gctcttttag cagcctttcc ttgaaaaggc catgatcctg gtcgagtcgg
    24901 ccatatcatg agggtaccat gatggggttc gtactctgct ggcatgtgat agcctaattt
    24961 ttttggactg tccatcatga taatctccct ttaaagtctt gatagccaaa agctttgagt
    25021 aagctacagt ctccctgttc gtccatgaga tagagacttg gcaatccaat accattaaag
    25081 gtattatttt tgacaaaaga ataaatggcc atgtcttgaa aataaagtct gtctccgatt
    25141 tggactggat tttcaaaact ataatcacca atcacatcgc ccgtcagaca ggtattagaa
    25201 gaaagtctgt aggtatgggc tttttcctgt gactcaaagc catttctcaa aggtggacga
    25261 tagggcatct caagtacatc aggcatatgg caggtcgcag aggcgtctaa aaccaagatt
    25321 tccataccgt tttctacaat atctaatacc tcagttgcta aataacccgc attaagcgca
    25381 atggcttcac caggctcgat atagatttca agattgtaag tttttcggat acgcttgatt
    25441 tctgaaatca gcaaatccac atcgtaacct tctcttgtaa tatgatgacc accacccata
    25501 ttgagccatt ttacctcatg taagtaggga ccaaactgtt cttctactgc tttcaaagtt
    25561 gtttgtaaat catctgctcc ctgctcgcaa agggtatgaa aatgaagtcc gtcaaccaaa
    25621 tctagcaaat cactcggaat cttgtctata gtaactccaa agcgagaacc tggtgcacaa
    25681 gggtcataga gcgcgtgatc tccttgagtt gaacactgag ggttgaggcg caaaccaaca
    25741 ctgacaccag cctctcgaca acgcggaccg tgtttacgca actgtctctc tgagttaaag
    25801 acgatatggt ccattatctc tagcaattcc tccaagtctg catccttgaa agcaggcgca
    25861 aatacatgga cttcaccagg aaattcttcc cttgccaatt tggcctcata gagtccacta
    25921 gctgtcgtac ctgatagata ctggctaatc aagggataag ttttgtagag ggaatatgcc
    25981 ttctgggcaa gcaagacctt gcaaccggcc tcttcttgta catattgtag aatgcggcaa
    26041 ttagcttcta acttggccaa gtcaataaca taggctggtg ttggtacttg ttctaacttc
    26101 attagtccac catttgtgga ttttcaacca caacccatgg caaaccatac tcattcaaag
    26161 cttccatgaa tggatctgga tctaactcct caaggttata cactccagct tgtttccaag
    26221 ttccgttcat gactaatttt gtcccaatca tggctggaac tcctgtcgta taagaaatag
    26281 cttgcgaacc aacctctgcg taacattcct gatggtcgca gacattgtag atatagatag
    26341 tctttttgac accgtctttg acacctgtaa agatacatcc aatattggtt tttccgactg
    26401 tacgtggccc aagactggca ggatctggaa gcaaggcttt caaaaattga attggaacaa
    26461 tttcttggcc gttaaagtta atggtatccg tacgaaggag tccaacattt tcaagacatt
    26521 tcatgtgcgt caagtaagat tgaccaaaag tcataaagaa acgaatgcgt ttgacacctg
    26581 gaatgttctt ggccaatgat tcgatttctt catggtgaag gagatacata tctttttgtc
    26641 caacttgagg gaaatcatac tcacgcttga tagacatagc ttcgacttcg acccatttcc
    26701 catcttccca gtaagaacct ggcgcagaaa cctcacggag attaatttct ggattaaagt
    26761 tggttgcaaa tggataaccg tggtcaccgc cattacagtc taaaatgtcg atataatgga
    26821 tttcatcaaa atagtgtttg agggcataag ctgaaaagac actagttaca cctgggtcaa
    26881 aaccagaacc aagaagagca gtcaagcctg cttctttgaa tttctcttga taagcccact
    26941 gccatgagta gtcaaagtag gctgtaaaac caagttcctt acaacgtttt tcgtagatag
    27001 cacgccactc agggtcttct gtgtcttctg cttcgtagtt ggctgtatcg atatagtgaa
    27061 cacctgttgc caaacaagca tccataatgg ttaaatcttg ataaggcaga gctacattca
    27121 aaacagcttc tggtttgtag ctttcaatca gggcaatcac ttcttcaacc ttgtcagcat
    27181 caagtgctgc agtttcaatt ttagtacttg ttttgccttc tagcttcgct ttcaagtcat
    27241 cgcattttga cttggtacgg ctagcaatca taatctctgt aaatgtttcg ctatcttgac
    27301 aaatctttga aatagcaact tgggcaacgc ccccacaacc aataactagt aaacgactca
    27361 tttttttcct tcctcttctt ctaaaatgtc ctcaacatac ttgggcaaca taaaggctcc
    27421 cacgtgtaag tttgcagtgt agtattctgt gaaaagctgg cgttttttcc agccttcctt
    27481 gtcaaaatct ttgacagggt ggtatttttt cgatgcaaat ccaaacaacc aatagccagc
    27541 tgggctagtt ggaatatggg cctgataaac ccgactgatt ggaaaggctt gattgacctt
    27601 gcggtgcatg cttcggcagg ccgactcatc ctcgtcaaag aagggactcc catgctggta
    27661 aatcatgatg ccgtcttcct tcagagctcg ataactattg ccgtagaatt ccttggtaaa
    27721 gagtccttcc gtatggccaa atggatctgt cgcatcgttg atgataatat cgtaatcatc
    27781 ttcgcagttt cgcaaaaagc gtagcccatt ttggtagtaa atggtaacac gaggatcatc
    27841 tagccctgca gcaaagtctg ggaaatactc acgacagacc tcgaccaaca tctcatccgg
    27901 ttccacaata tcaatttgct ccagttcagg atagagggtt aatacttggg caacaccgcc
    27961 gtcaccaccc ccaataacca atactttctt tggatttggg tggacagcca tgggaacgtg
    28021 aacggtcatt tcattgtaga cgaaatcatc cgcatctgag aacaagacat ggccatttaa
    28081 aatcagtatt ttcccaaaag ctggcgtatc caagacttcg atatcctgcc attcactttt
    28141 tccagcgtaa agttgcttgg ctgttctcag agacaatttg acatctggag tatgaacttc
    28201 agaaaaccat aaatccatct atttctcctt atattatatt tagcgcagtt agctactgcc
    28261 aaagcccaag tggtatactt ggaataagcc actgtggatt agttcatttc ctccaatcgc
    28321 ttgacgattt ccgaaaggct ctaaccacag cttttgtttc aattggtaat gagtttgata
    28381 acgcatagac gttttatctc gtctaaggta acaaggcaaa aagttcgtgg ataaccaagt
    28441 agacttgaaa tactacatct ggaggtactc ccatgcttta tgtgggcatt gatatcgcta
    28501 aaaataaaca cgatgttaca gccttgaatg ttcaaggaaa aactgttctt aaaccactca
    28561 ctttttcaaa taataaagct ggttttgaac tcttagatct gtctcttcga cagctcaacc
    28621 aagactgtct catcgctctt gaagatactg gacattatgc ctttaatcta ctgaacttcc
    28681 tgcatgaaca aggatataaa gtttacacct acaatccttt gctcatcaag gaatttgcca
    28741 aatcattatc acttcgcaag actaaaacgg ataagaaaga cgctcatggc atcgctctta
    28801 aacttctttc tgaccccaat cgtgaacaat ttcaacacga taatcggcaa gtagaactaa
    28861 aaatactggc tagacatatt catcgtctca agaaaaacag tctgattgga aagtacaata
    28921 cactcgttgt cttgatatca tctttcctga gttggataaa atcgttggaa agcattcaga
    28981 atatacctac caactcttga cacgctaccc taatcctcag aaaaggattg aggcaggatt
    29041 tgataagctg atagaaatta agcgattgac cgcttctaat tcaagggctt tttgccgtgc
    29101 tctaaaatca tcgccaaatc atcaaattga aataagaaat agtttagata aaactattga
    29161 cttttcttat agtttgtctt tctcttaata acgttgatat gattgacctc tggatcttcc
    29221 gtcccttgga gggagcaacc acgttccttg gcgaattgga tatagtctac aatttctcgt
    29281 gtaatgcgtt caccaggagc caagatagga atccctggag gatagcacat gacaaattct
    29341 ccacagacct gtccaacaga ctcatctaag gtcaaacttt ttctctctga atagaaggct
    29401 tcttgtggag acagcaccaa ctcgggctga atatattctc cagctattaa gtccttccca
    29461 tctcgtgaat agagtctctt aatatcagcc agagcaccaa ccaagcgctc gatgtcttgg
    29521 atgcggtcgc cgatggaaat ataggccaag atattgccga tatcaccaaa ctcgatctga
    29581 atgtcgtatt cgtctcgcaa gaggtcataa acctcgatac ctgttaagcc tattccctga
    29641 gtgtaaactg acaacttggt tacatcaaaa tcacagaccg acacaccatc tattaactct
    29701 tttgagtaag catagtaacc gccaatggca ttgatttcat gacgagcgta ctcggatagc
    29761 tcaatgactt cctcaaacga ctctttacca cgaagggcca agttgcgacg tgaaatatcc
    29821 aaactagcca tcaataagta agaggcagat gtagactggg tcaggtttat aatctgacga
    29881 acgtactcgg gattcatctg ctccccgatt aaaagaagcg aactttgtgt caaactccca
    29941 ccagacttat gcatggaaac tgctgccata tcagctcctg catccatagc agaaattgga
    30001 agtttaccag tgaaatgcaa atgcgctcca tgggcttcat ctactaaaac catcatgcca
    30061 gcttcatgag ccatttctgt caaccccttt aggtctgaac agatgccgta gtaagtagga
    30121 ttgttgatta ggatagcctt agcatctgga tggtccttta tggcctgtgc tactcggtca
    30181 ttttcaagac ctaaagcgat accaatctta ggatctacac tcatctcgat atagatggga
    30241 atggcaccac atagaaccaa cgcattgata gcagatttat ggacatttcg tggcagaata
    30301 atcttatctc ctgccttgca ggttgccaga atcatagtct gcaccgatga agttgttcca
    30361 ccaatcatta gaaaggcatg gctagctcca aaagcatctg cagccagctc ctctgcatca
    30421 cgaataatcg aaataggatg gcctaaatta tccaagggtt tcatcgaatt gacatcaatg
    30481 cctacacatt tttctcctaa gagttcgaca agttctggat ttccccgtcc acgcttgtga
    30541 cctggaacat caaagggaac aatccttttc ttgcgtaact tcaccaaggc ttcataaatt
    30601 ggggcttggt tttgatctaa ctctttcaaa acatactcct ttcaatattt ttaggacctt
    30661 atgaaaacta aggaactaaa ggttgactca tgaaaaaaga gcaggttttc acctgctctg
    30721 caatcttctg acgtgtttat tttggtttct gttgagtatg tctgttcccg atgtttccta
    30781 actctctagt agcaaatatt acgtacttta ttgatcgttt cacaagatga cgtgtgcttt
    30841 caccacacta aaaatttatg aattaggaca agtgtcctaa catcaactta taaaagtagg
    30901 cttttaaccc tatcaataat gtggcttttc aaccacgctt cggcattcaa ccctgcctgt
    30961 ccgtaggcat tttttactcg ggtttatatt tgctagaaaa catcatctca ttttctaagc
    31021 tttattacta tatcatgttt ttaagaactt gtaaagtatt ttttgataaa aaacaaaaat
    31081 atagtagatt gaaactagaa tagtacactt ctgcttctaa aacattatta gaaatagatt
    31141 ttactgtcct gatcgatttg ttctgttctt gtttcatttt actatatgtt cgtaaatgaa
    31201 agttctataa tgaagttagc cacccagccc tcctaaaaat tagatggttc aactagctga
    31261 tagctcttgt aggcataaga aaacacctct gtgttatact tgttgttcaa ccacaaacac
    31321 aagaaaggca cagagatgca agacaattat actacaaaag ccaaacattt gacaatcgat
    31381 agccgtcgct taatcgaaag atggaaaaaa gaagggaaat caaatagaga aattgcctct
    31441 ctgcttggaa aagttcctca aactatccac actgaaatca agcgtgggac agtccgacaa
    31501 tgtcttggaa aagggcgctt caaagaggtt tattctgccg actatgctca acagtcttat
    31561 gaaaacaatc gcaagcgctc ggtcaggaaa tcaagcgtga ccaaggaact aaaggaaaag
    31621 attctccact atcataacca aaaattttcg cctgaaatga tggtgatggt taaaggggtt
    31681 aacgtgggaa tttcaaccat ttactattgg attcatcatg gaaaattggg gttaagcaaa
    31741 caggatctgc tttaccctag aaaaggaaaa gcgcttaaga aacaggctag caccaacttt
    31801 aaatctgctg gtcaatccat cgaacagcgg tctgaagcta tcaatcttcg cttggagaat
    31861 gggcattatg agattgatac ggttctactt acgagagcga aaaactactg tttgcttgtc
    31921 ttgacggatc gaaagagtag acatcagatc atccgattga ttccaaataa aagtgctgat
    31981 gtggtcaatc aggctctaaa actcatctta aaacaacaca agattctttc catcacggca
    32041 gataatggaa cggaattcaa tcgcttgttt gatgtatttt ctgaggagca catctattat
    32101 gcgcacccct atgcctcttg ggaaagggga actaatgaga atcacaacag gctcattcgt
    32161 agatggttac ctaagggaat caagaaaatg actcccaaag aagtcgcatt catcgaaaag
    32221 tggattaaca actatcctaa aaaatgcttg gactacaagt cacccagaga agacttctgg
    32281 atggctaact tgaacttgaa atttagcgtc agaaacaaat cacgaaattg attcaaattt
    32341 tgcaggtcgt ttaaatatcc tgcgtgcggg tgttcttgat gctaacgatg gaattatttc
    32401 cattgctggt gtggttatcg gagttgccag tgccacgagc aatatctgga ttatcttttt
    32461 atcaggtttt gcggctatct tagctggtgc cttttcaatg gctggtggag aatatgtatc
    32521 cgtttcaact ccaaaagata ccgaggaagc tgccgtttcg cgagaaaaac tcttgctaga
    32581 ccaagatagg gaactagcca aaaaatccct ctatgcttct tatatccaaa atggagaatt
    32641 caaaacttct gcccaactct tgactaataa gatctttctt aaaaatccac tcaaggctct
    32701 ggtagaggaa aaatatggga ttgagtatga agaatttacc aatccttggc acgctgccat
    32761 ttctagcttc gttgcctttt tccttagaag tttgcctcca atgctgtcag tgaccatttt
    32821 tccaagtgat taccgcatcc ctgctaccgt ccttattgtc ggtgtggccc ttcttctcac
    32881 tggttacaca agtgctagac ttggaaaagc cccaaccaaa acagctatga ttcggaacct
    32941 tgctattggt ctcttgacca tgggagttac cttcctgctc gaacaacttt tcagcattta
    33001 gaatacaaga aatacctcga ttttgaagtc gaggtatctt ttttacattt gcacaatctt
    33061 gcgataactt cttgaagtaa tcataaaaat cagcacatag gcgatgagga agatagcgca
    33121 gatagacaag gtcacaatca acatcatagt cgtatccagt acaccaatca cttttaaaat
    33181 caggctaagc atatggtagg caaaggctag atgtaggaag gcaaagagca aaggaaggaa
    33241 gaaaacagtt aaaacctgtt tgttgatggt ttgcttgatt tgcttttggt ccaaaccgac
    33301 tttctgcaag ataataaagc gttcacggtc ttcgtagcct tcagaaattt gtttgtagta
    33361 gatgaccaga acagttccga ccataaagat aatggatagg aaaataccga taaagaagac
    33421 accaccaaag agggcactca tctgagcact agcatctgct agagtgctac cataaacata
    33481 gctaccttct gtgtctaatt gagcattaaa ttgattgagg tagttttcat actcctcagc
    33541 gaccttgagt tgttcttctt cgctggcatc tacattcata ccaccgtaaa actgattata
    33601 gatagccgaa tctgggaatt gatccaaaaa ggcttgtaaa tcaggaacaa caaggtaatt
    33661 gtaatcagta gtcaagatat taaacttatt tggaacatgg ttgacaatga aatctttatt
    33721 aaattcttct ttgacagaaa attgatgatc atttagagtt agagctttct gtcctttcag
    33781 tccgtcattt ttggcaaaga gaccgacctc atttcctgat agagacagtt tttgaccagt
    33841 catattttca taatcttttt ggtcaaatac catgaaaact gtttttggtt ggacacggtt
    33901 ttgtcctttt tcaaaaatag ttaacttggt tccttcttga tttgcaatac caaagttact
    33961 gtaacgaagc acttctttct ctttaatctt ataacctttg tcacttgcaa actggctcaa
    34021 gagtttgtcc aaatcttctt tttcaacatt ttgccctgaa accccaaaat catgaggatt
    34081 tagaactttt ttaaaggatt ctgcggaatt gaaaatgctt gtcgctgctg acatggttac
    34141 caaaaccatt gttgacaaaa tagcgatagt tgctagtcca actgcatttt tcttcatacg
    34201 gaaaatcaag ttagaaacag atatgagatt attaggttgg taatagtatt tcttattttt
    34261 ctttaagatt tgaaggaaaa cggtaatccc tgcattgaac aaaagataag taccaaagat
    34321 aaccagtaaa acagctatga agaaggttgt taaggctgta agaggatctt ttaccgtaag
    34381 ggcaagataa tatccaatcc ctaaacttat ggaaccaaga atagtttgga gaggaaggaa
    34441 gcgacctttt ttctctccgc tagctttctc acgtgagagc tggagggcat tcatacgggc
    34501 gattcgaagg gcattcagga acatgaggcc taggaaaatc aaaccgaaga caagaagtac
    34561 tgtaatgaca actttcatct ggaaggtagc gaccagttcc accttcaatt tcatcagttt
    34621 gagtaggaaa gcgaaaatca acttgtcaaa caaggctcca ataccgatac ccgctccaac
    34681 agttagaatc ccaaatacca ctaactcctt aaaggtcata ctgataagat gacgcttctc
    34741 caagcccaac atgccataaa ttcctagttc cttggaacgg ttcttcatga caaaactatt
    34801 ggcatagaga acgataatgg ctgacgcaag ggtgacgaca aacataccaa atccaagtgt
    34861 agcctgaatg gttgttcctc cacggatttc cgcaatctta ggattgaagg ttagagagta
    34921 aaagagatag gtgacagtga ctgccaagag aacagccagc gcaaaaggat agtagagttt
    34981 gcggttttta atcaagttcg ataccgctaa cttattggtt aatcgaaaca tactaattca
    35041 cctcgcttgc catgacagtc aaggtatcag agatttcttg gaacatctga cgttctgtct
    35101 tctctccacg gtagatttga ttgtaaagaa tgccgtcttt gataaagagt acacgtttag
    35161 ctctgctagc tgctgctgtt gagtgggtta ccatgagaat ggtttggccg cgctcattga
    35221 tttcatcaaa gacatcaagt aaggctgcag atgacttgga gtcaagagct cctgtcggtt
    35281 cgtccgcaag gagaatttca ggttctgtga tgatggcgcg ggctactgct acacgctgtt
    35341 tctgaccacc agaaatctcg taagggtact tctcttgtaa ttggtttatt cccagattct
    35401 cagctgtcac caccaatttc ttcatcatct ctgtaatagg tcttcttgac aagacaagcg
    35461 gaagcaagat attgtccttt acagatagag tatctagcaa gttaaagtct tggaagacaa
    35521 agcccaactt ttcacgacgg aagctagagg cctgtgaatt tttaatggtt gcggtgtcag
    35581 ttccattcaa gtaaacctga ccacgacttg gtttatccag catagctaga atattgagaa
    35641 gagttgattt accagaacca gactcaccca tgatggcaac gtagtcaccc ttttcgacgg
    35701 taaagtgaat atccttgagg gcttctactt ggttgccctg aaaacgtgtt ttataaattt
    35761 tttgaacgtg ttttacatct aaaagtgtca tgagaatctc ctttcttaat atcccatcaa
    35821 atgaaatgta gcttgcatca tagtgcatcc cagctgaacg cgctcaattt ctttgtgact
    35881 tggttttcta gttttcttat gtaagatttg tttcatgatg ttactccttt gttctttatg
    35941 agtctagttt acatcaaaaa aagaccgctt gccataacct aaccttacaa aagagacttt
    36001 aatcttacat ttttgtaaga ttgggtgaaa tataagcaaa attacttaga aaatgatttg
    36061 atttcctatt tttaaagttg taaaatataa gtgtgaaaag gcttactttg aaaaggagga
    36121 agcgggaact aacattttag taaggttacc tagataacat accattcaat ttaacacttg
    36181 caagtcgttc aacctataag gaaagaaggt gcgctttaat gaaacacaaa gaacatatac
    36241 tcatcggact tctctatctg ctctctccat tcatcggtca gctcttagtt gaacacacac
    36301 actttatcgg tacagaattt accggcactg cttatgttat ttgctggtta tcagttgtta
    36361 tcagcatcca ccatttttcc aaaaatgtat tgtctcaaca gcaaaaatag attaaaaaac
    36421 tgcgtttaaa ttactgcttt tatagtaaaa tgaaataaga acaggacaaa tcgatcagga
    36481 cagtcaaatc gatttctaac aattttttag aagtataggt gtcctattct agttccaatc
    36541 cactatagtt tgtggatgaa gctggcgaaa tattattaat actattcaaa aatcaaagtg
    36601 caaactatat caacttcaca ttgccgacta aattacagcc tgcggctggc ttcctagttt
    36661 gcactttgat ttttattgag tataaaagta aaaaagcttt aaatcaagca gtttagacta
    36721 ttgatttaaa gctttttgcg tattccaaat cttttgtaaa acctcaccaa aaccagcctt
    36781 cattatcgtc aatggcttga gcttctttgc gtttacgtgg gcctgttccg tacatttctg
    36841 cttcgatttc ttccttggtt ggcatgatag aagctaggat gatatagata atcaccccaa
    36901 gtccaaagtt tgcgactgta aaaatggcaa acagaaaacg tacaagggta acatcaaagt
    36961 tccacttgtc tgacagacct gctaaaactc ctgaaatcat gcgatttcgt ctcattttat
    37021 aaaacttact gttcatgata tttcctcttt ctgctaggtt agactagtat atcacggata
    37081 ggctcggctt tcatcagtcc tcaggctgat ttactaatag caactttcct cgacaaagtc
    37141 cacagcgata gcgttgggta tcaatcctac gcttacgctg ataagtttgc tggcaggatt
    37201 ggcaacgata gagcttgatt ggcttggagt tactattggg caaggatggt acaaaccgta
    37261 atccatccac tgctttcaac agttccttaa aatcccgatc cttgtgttga tagcctttcc
    37321 cttgaaaata gaggtgataa tgacagagtt catgtcggac aattttccta aaaacgtcca
    37381 accccagttc ctgataaacc ttgggattaa aatccaaatg cccatctttg gggaaaaatc
    37441 gcccacctgt cgaacgtaga cgcctattcc actggacatg atggataaaa ggtctgccga
    37501 agtcttctag tgaaacctgc ttgacgtaat cagtcagttt catttggagc taggagagac
    37561 agattaactt tttcacgttc agtatcaatt ttcttaaccc aaacgctcac caaatctcca
    37621 actgccacca cttgactagg gtgtttgata aacttgcgac tcatatggga aatatggatg
    37681 agaccgtcct catgaattcc gatatcaaca aaagcaccga aatcaacaac attacgcacc
    37741 actccttcta gcttttgtcc aaccactaag tccttgatat ctaggacatc ttgacggaga
    37801 actggagcat caaaggaatc acggaaatct cgacctggtt tgagaagatc tgcaatgata
    37861 tctttaagag tttctggacc aaggtctaac tcttgcgcca tttccttgac tgaaagcgac
    37921 ttgagtttac tttgggcctc ttcattcaga tccttaatgt ccaagcattt gaagagttcc
    37981 ttaacggcag cgtaattttc tgggtgaact cctgtattat caaggatatt gctactttca
    38041 gggatacgga ggaaaccagc agcctgttca aaagccttgg cccccaaacg aggaactttc
    38101 ttgatttggg agcgtgaagt gatttttccc tcttcctcac ggtatttgac gatattttca
    38161 gaaatggttt tattgagtcc agctacgtgt gaaagaagag ctgggctagc tgtattgaca
    38221 ttgacaccaa cttggttaac cactgtatcg acaacaaagt ccagactctc agatagtttc
    38281 ttctgactga catcgtgttg gtattgaccg acaccaattg acttaggatc gattttgacc
    38341 aattccgcaa gaggatcttg caaacgacgg gcgatagaaa tggcagagcg tttttcaacg
    38401 gtcaagtctg gaaactcctg acgagcaagt tcgctggcag aatagacaga agcaccactt
    38461 tcattaacga taacatagct gacttcaggg aaatctttca gaacttccgc tacaaaagct
    38521 tcactttcac gactggccgt tccatttcca atggcaataa tctctacacc gtattgacca
    38581 attaaatctg ctaaatcttt cttggcttct tcgatttgac gagctgatgc tggtttaaca
    38641 ggataaataa cctgagttgt cagcattttt cctgttgcat ccacgacagc tagcttggca
    38701 cctgtacgaa aggctgggtc aaacccaaga accacgcgcc ctttcagtgg agcaaccaag
    38761 aggagattgc gcagattgtc agaaaaaagt tggatagctc cctcttcagc tttctcagtt
    38821 aattctgtcc gaatacgacg ctcaatagca ggcaagacct ttttcttaac ggattgctga
    38881 acaacttcat caatataagc atttttcacc ttgaaacgag tagcaaagaa ggcaagaata
    38941 cggtccgtcg catgttcaaa accgatcttc aagacaccaa gtttctcccc acgattgaga
    39001 gccaaggtac gatagccttg catagttcca actgtctctg aaaaatcata ataaatctga
    39061 aaaacctgct tttcatcaag actttcatcc ttggcttgag aagtgagttt agagtgtctc
    39121 agcacttcct gataagtcat agaacgcaag gtcacatctt ccgataaggc ttcgaccaaa
    39181 atatcaactg caccggtcaa ggcttccttg ccagtcgcaa atccttcaca gacgaacttt
    39241 tcagcttctt tctctaagtc aactatattc tgcaaaatca aacgagcaag aggaaagagt
    39301 ccagcttcac gggcaatggt tgccttggta cgacgctttt ccttataagg aagatagagt
    39361 tcttcaacgt ctgctaattt ttcggcaact aagatagctt cttccaattc cttggtcaac
    39421 ttaccttgtt cttgaatctt agctaagaca gcttccttac ggtcattgag atttgtcaga
    39481 cttttatcca aatcaataat agccttaatc gccacctcat ccagactacc agtcatgtcc
    39541 ttgcgataac gcgcgataaa gggaatagtc gccccttcag ctgtcaaact tagaacggta
    39601 tcaatttgct ttaacgtcac tcccaaatcc tgagagattt tttcatattt tttatccata
    39661 aatctattat accacaagct aaacgtttca aattaactcg tagaacattt aaaaaatatg
    39721 taggaaatag atttatatgc tacagcgcaa taacttgcac ttaaagagca ttgccacctt
    39781 tttttaacca agccatgata tcaaaagtat ttaatggatc agacataata gccagttctg
    39841 gaagatgttc ctgacctgga ataacacatt gacttttcaa atttttatat ggacgattga
    39901 ctaaaattaa tttattagaa taaggaagat tatccatctt atttaaaatt tcttcactag
    39961 ctgaatcttt attatcaaat ttaaaataaa gattattcca atttatgcgt ttttttcttt
    40021 tttcccactt agttcgtgct tcttcaatac tagaataatg tagaaaatga atatctatat
    40081 ctcctaagtg ccccaaagga taaacttcat gagtccagct cggtgaaata agttcctctt
    40141 cgaaaacaag ttcttgttcc atataataac gaaaatgctt tgtaagttta taataatcat
    40201 caggaagaat aaataaacca acaaaaggtg ttctatattg aaaaccaagc tgtttataaa
    40261 ttaatcctcc aacacaatta ttacttataa tcgtaaaatc taatctatca agctcaagaa
    40321 aagggaaaat tcctttctct gcagctatta acttatgata aacaatatca gaatctaaat
    40381 attcaccgtc attttttaac caagcactaa aatttgccaa ttcttgaata tattgttttt
    40441 tcgctctttc tatatcatag ttttctaaga cggcgcaatc tttgattcta ttttcataat
    40501 tttctaatat gattttgtag gagtctttta gaggtttagc atctataaca ggtttataga
    40561 tatatgtcgg gaaattaata taggttgcag ttttagagtg aatataaagt ctccaaataa
    40621 ggttgtttat atcaaattga tttatttttc gtaaaagctt actattgaat aattttccaa
    40681 ataatgagcg atattgtttt ctaattcgat gatctgtatc atccatcttt tgtaaaactt
    40741 gaacattcgt taaattttct gtcaaccaat tatccccccc ccaaaggata aaagtaaaat
    40801 actccatcaa ccaaatcagc aaaatgacca agaacaacat cagaatcgga taattttatc
    40861 gcatgataca tcttttcaaa tgtccaatca aataatgaat catttgaaga tagaaacgta
    40921 atataatctc ctgtaatcat atcagacaac tcagcaaaag aattctcatc tataatctta
    40981 atattaaatg atagattcat ctgttggcta atggaagcta tctcctctgt agattgattt
    41041 acaataataa cttctatatc ttttaatgtt tgtctctcca ctattgacaa agactctaat
    41101 aaactatttt tatctccttg atgtaacaaa acaacactaa ttgagtaagt cag
//
LOCUS       DAVKMJ010000019        39917 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000019 DAVKMJ010000000
VERSION     DAVKMJ010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39917
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.019"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            343..1386
                     /locus_tag="VW348_001009"
     CDS             343..1386
                     /locus_tag="VW348_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEU9745924.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIIARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            1553..3640
                     /gene="topA"
                     /locus_tag="VW348_001010"
     CDS             1553..3640
                     /gene="topA"
                     /locus_tag="VW348_001010"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEU9745925.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEENIK"
     gene            3746..4105
                     /locus_tag="VW348_001011"
     CDS             3746..4105
                     /locus_tag="VW348_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEU9745926.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4198..4830
                     /locus_tag="VW348_001012"
     CDS             4198..4830
                     /locus_tag="VW348_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEU9745927.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGVLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQVGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            4874..5530
                     /locus_tag="VW348_001013"
     CDS             4874..5530
                     /locus_tag="VW348_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEU9745928.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5549..6169
                     /locus_tag="VW348_001014"
                     /pseudo
     CDS             5549..6169
                     /locus_tag="VW348_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
     gene            6197..6631
                     /locus_tag="VW348_001015"
     CDS             6197..6631
                     /locus_tag="VW348_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HEU9745929.1"
                     /translation="MVAGSMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            6643..7680
                     /gene="leuB"
                     /locus_tag="VW348_001016"
     CDS             6643..7680
                     /gene="leuB"
                     /locus_tag="VW348_001016"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEU9745930.1"
                     /translation="MAKKIVALVGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAWPPLPDETLKASREADAILLATIGSPQYDGAVVRPEQGLMTLRKELNLYAN
                     IRPVKIFDSLKHLSPLKLERIAGVDFVVVRELTGGIYFGDHILEERNARDINDYSYEE
                     VERIIRKAFEIARNRRKILTSIDKQNVLATSKLWRKVAEEVAQDFSDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIHGSV
                     PDIAGQGIANPISMILSVSMMLRDSFGGYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            7677..7946
                     /locus_tag="VW348_001017"
     CDS             7677..7946
                     /locus_tag="VW348_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEU9745931.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            7950..8309
                     /gene="leuD"
                     /locus_tag="VW348_001018"
     CDS             7950..8309
                     /gene="leuD"
                     /locus_tag="VW348_001018"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEU9745932.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8528..8671
                     /locus_tag="VW348_001019"
     CDS             8528..8671
                     /locus_tag="VW348_001019"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745933.1"
                     /translation="MTSDKAGLERKFAAKEGKRNKPGVVLCGSMDELCALAQLNPKIE
                     AFY"
     gene            8690..8944
                     /locus_tag="VW348_001020"
     CDS             8690..8944
                     /locus_tag="VW348_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745934.1"
                     /translation="MLLGCILPWKPEAFEKLKAYGDGREELMTDVRGTSCFVIKFGKA
                     GEQLAAKLWEEGKMVYASYASMTKRLKLAMRARCNGVYGR"
     gene            8934..9095
                     /locus_tag="VW348_001021"
     CDS             8934..9095
                     /locus_tag="VW348_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745935.1"
                     /translation="MVDKDGKLIPEQGGARSTSPAPVVIRKGLDIDKIMMHLSDTFNL
                     WDYRQVEYY"
     gene            9258..9621
                     /locus_tag="VW348_001022"
                     /pseudo
     CDS             9258..9621
                     /locus_tag="VW348_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828316.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
     gene            9630..9911
                     /locus_tag="VW348_001023"
     CDS             9630..9911
                     /locus_tag="VW348_001023"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745936.1"
                     /translation="MYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTKLLCIYSEG
                     DSFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVPKLILSWSHRN"
     gene            9971..11188
                     /locus_tag="VW348_001024"
     CDS             9971..11188
                     /locus_tag="VW348_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEU9745937.1"
                     /translation="MDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEIAKELTD
                     GNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKETQLIGG
                     QDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLPSKYVYE
                     LYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEINRGEIS
                     KIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDRSVDTFD
                     FAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSHYHIGPS
                     YFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNEQKDQAVA
                     DDNEGDENDDADY"
     gene            11175..12491
                     /locus_tag="VW348_001025"
     CDS             11175..12491
                     /locus_tag="VW348_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEU9745938.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLVYLFPKYLQAAIRKGLYKEYHRFSHNDSNVKGV
                     IDVRSHLKKNLPFTGNIAYATREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            12666..13652
                     /locus_tag="VW348_001026"
     CDS             12666..13652
                     /locus_tag="VW348_001026"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEU9745939.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            13716..13787
                     /locus_tag="VW348_001027"
     tRNA            13716..13787
                     /locus_tag="VW348_001027"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13749..13751,aa:Arg,seq:ccg)
     gene            13970..14668
                     /locus_tag="VW348_001028"
     CDS             13970..14668
                     /locus_tag="VW348_001028"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEU9745940.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFNQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVIIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            14659..18198
                     /gene="smc"
                     /locus_tag="VW348_001029"
     CDS             14659..18198
                     /gene="smc"
                     /locus_tag="VW348_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEU9745941.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLATLEDKRSS
                     LSQEKSDKESSLALLEENLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLATAKEKAGQQKAELETAKEQVQK
                     LLADYQVCAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLEIILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVHYQTALEIALGASSQHIIVEDEESATKAIDLLKR
                     NRSGRATFLPLTTIKARTISSQNQDTIAASPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLRSDEVSLKNLQDELARLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEELNRLSEGEWQADKEKCQERLTTITSEKNNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDIEQEEIQRLLQEKVDN
                     LEKVDTDLLSQQADEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNLDAIEQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEVIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            18195..18989
                     /locus_tag="VW348_001030"
     CDS             18195..18989
                     /locus_tag="VW348_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9745942.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLVSYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEDGEAWVNENVPGVKAMTTGFESIDIVLDYVDKGVAIVELVKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            18989..19807
                     /locus_tag="VW348_001031"
     CDS             18989..19807
                     /locus_tag="VW348_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9745943.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLQAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            19811..21100
                     /gene="ftsY"
                     /locus_tag="VW348_001032"
     CDS             19811..21100
                     /gene="ftsY"
                     /locus_tag="VW348_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEU9745944.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTVEENNSEVLEPEAPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDVLRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVTEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(21146..22633)
                     /locus_tag="VW348_001033"
     CDS             complement(21146..22633)
                     /locus_tag="VW348_001033"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEU9745945.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDITYRQDGRLE"
     gene            complement(22782..23522)
                     /locus_tag="VW348_001034"
     CDS             complement(22782..23522)
                     /locus_tag="VW348_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9745946.1"
                     /translation="MVKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(23522..25687)
                     /locus_tag="VW348_001035"
     CDS             complement(23522..25687)
                     /locus_tag="VW348_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU9745947.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            25857..26810
                     /locus_tag="VW348_001036"
     CDS             25857..26810
                     /locus_tag="VW348_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9745948.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            26887..28875
                     /gene="uvrB"
                     /locus_tag="VW348_001037"
     CDS             26887..28875
                     /gene="uvrB"
                     /locus_tag="VW348_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEU9745949.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            28885..29448
                     /locus_tag="VW348_001038"
     CDS             28885..29448
                     /locus_tag="VW348_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9745950.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNIGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            29414..29902
                     /locus_tag="VW348_001039"
     CDS             29414..29902
                     /locus_tag="VW348_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9745951.1"
                     /translation="MTVIIKSMETPKEIEGKSLVHWQTWRESYDDLLPAEFQDTMTLE
                     RCRFFSQKYPENTLIAMDGVKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            29976..30443
                     /locus_tag="VW348_001040"
     CDS             29976..30443
                     /locus_tag="VW348_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU9745952.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(30440..30955)
                     /locus_tag="VW348_001041"
     CDS             complement(30440..30955)
                     /locus_tag="VW348_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEU9745953.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(30967..31494)
                     /locus_tag="VW348_001042"
     CDS             complement(30967..31494)
                     /locus_tag="VW348_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9745954.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(31776..32339)
                     /locus_tag="VW348_001043"
     CDS             complement(31776..32339)
                     /locus_tag="VW348_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9745955.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(32323..32874)
                     /gene="coaC"
                     /locus_tag="VW348_001044"
     CDS             complement(32323..32874)
                     /gene="coaC"
                     /locus_tag="VW348_001044"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEU9745956.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(32886..33575)
                     /gene="coaB"
                     /locus_tag="VW348_001045"
     CDS             complement(32886..33575)
                     /gene="coaB"
                     /locus_tag="VW348_001045"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEU9745957.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISAGQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            33805..35475
                     /locus_tag="VW348_001046"
     CDS             33805..35475
                     /locus_tag="VW348_001046"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEU9745958.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKSQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            35803..36978
                     /gene="mutY"
                     /locus_tag="VW348_001047"
     CDS             35803..36978
                     /gene="mutY"
                     /locus_tag="VW348_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEU9745959.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            37033..37737
                     /locus_tag="VW348_001048"
     CDS             37033..37737
                     /locus_tag="VW348_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9745960.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            37730..39079
                     /gene="vicK"
                     /locus_tag="VW348_001049"
     CDS             37730..39079
                     /gene="vicK"
                     /locus_tag="VW348_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEU9745961.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            39081..39890
                     /locus_tag="VW348_001050"
     CDS             39081..39890
                     /locus_tag="VW348_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU9745962.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
BASE COUNT        12261 a         7097 c         8906 g        11653 t
ORIGIN      
        1 gtagagatta caaggcttgt ttaagaaaga attcaaagac cttgacaaat aaaaataaaa
       61 tggttattat aaaaaatggt ctgaaataga tgatgatact tttcgaaaat ctttttacat
      121 cagctcagct ttgccttgct gtgttttgag caagctacgg ttagcttccg agtttgattt
      181 tcatttacta gaaatgaaac tgatgagaga tatcagtaga catctgagtc aggatattat
      241 ggaaaatgat aaaaagagct cgtgagattg gcatatcaga ctactaaagt attgagtttg
      301 ttaggatttt agcgactagt tagctgggaa aggaagatat ttgtgacaaa taataaactg
      361 tattcgttga tagaatttag aaataaaata tatgaagaat tagaactttc cagaagtgat
      421 ttagcgattt tactatgtgc catgcttatc gcctctatcg gattaaatat ggattcgact
      481 cccgtgatta ttggagccat gttaatctct cctttgatga cacctattct gggagtgggg
      541 ctctctctag ctatatttga ttttaaattg ttaagaaaat cttttaaaat attagctatt
      601 caaattcttg ccagtctaat agcttcaaca ctttattttt atctttctcc catttcgtat
      661 gctagttcgg agattattgc tagaacctct ccgactattt gggatgttct cattgctttt
      721 gtaggaggga tagcaggtat tattggtgct aggaaaaaag agaccaataa tattgttcct
      781 ggtgttgcta ttgcaaccgc cttgatgcct cctctttgta cagtaggtta tgctattgct
      841 tctgctaatc taaaatttat cataggctcc tcttacctat tcctcatcaa ttgtagcttt
      901 attgtcattg cgacttatat aggtgttagg ttgatgatgg ttaagaaaca ttattttaaa
      961 gataatgaag aagactctaa aatgcgtagg attttgcttc tagttgctgt tttgctgatg
     1021 attccgagtt tcatctctgc aacgacttta gtgagagaaa cgttgaaaaa agagtccctt
     1081 aagaaattta tatcagagca gtttcagggg cataatattt tgaaaaaaac ctattctaaa
     1141 aagactcata ccctaaagct aaccatttca ggaaattatt tgacagaaga agaactcgat
     1201 atgatttcaa gtaagagagg tgactatggt ttaagtgatg tttctgttca agtttcacaa
     1261 ttgtctgatt cagaacaact tagtaaggaa gaactggtgg agtatttctt ccagtatatc
     1321 aaggataagg aagcaaaaga aaaggaaaaa gctaataagt tttatacaga gtctgaggag
     1381 caataatttc ttgagaatag ctggtttttc tcgtgagtct tctatgtata tcaaaggaag
     1441 actgaggttt taagtataaa acttttcttc tattatagta gctaagtctt gacagggttc
     1501 aaaaaatggt ttacacttta taaagtttat tactttgaaa aggtgtgata ctgtggctac
     1561 ggcaacaaaa aagaaaaaat caacagttaa aaaaaatcta gtcatcgtgg agtcgcctgc
     1621 taaggccaag acgattgaaa aatatctagg cagaaactac aaggttttag ccagtgtcgg
     1681 gcatatccgt gatttgaaga aatccagtat gtccgttgat attgaaaata attatgaacc
     1741 gcaatatatc aatatccgag gaaaaggccc tcttatcaat gacttgaaaa aagaagctaa
     1801 aaaagctaat aaagtttttc tcgcgagtga cccggaccgt gaaggagaag cgatttcttg
     1861 gcatttggcc catattctca acttggatga aaatgatgcc aaccgtgtgg tcttcaatga
     1921 aatcaccaag gatgcagtca aaaatgcttt taaagaacct cgtaagatcg atatggactt
     1981 ggtcgatgcc caacaagctc gtcggatctt ggatcgcttg gtagggtatt cgatttcgcc
     2041 tattttgtgg aagaaggtca agaagggctt gtcagcaggt cgcgttcagt ccattgccct
     2101 taaactcatc attgaccgtg aaaatgaaat caatgccttc cagccagaag aatactggac
     2161 agttgatgct gtctttaaaa agggaaccaa acaatttcat gcttccttct atggagtaga
     2221 tggtaaaaag atgaaactga ccagcaatga cgaagtcaag gaagtcttgt ctcgtctgac
     2281 tagtaaagac ttttcagtag atcaggtgga taagaaagag cgcaagcgca atgctccttt
     2341 accctatacc acttcatcta tgcagatgga tgctgccaat aaaatcaatt tccgtactcg
     2401 aaaaaccatg atggttgccc aacagctcta tgaaggaatt aatatcggtt ctggtgttca
     2461 aggtttgatt acctatatgc gtaccgattc gactcgtatc agtcctgtag cgcaaaatga
     2521 ggcggcaagc ttcattacgg atcgttttgg tagtaagtat tctaagcacg gtagcaaggt
     2581 caaaaacgca tcaggtgctc aggatgccca tgaggctatt cgtccgtcaa gtgtctttaa
     2641 tacaccagaa agcatcgcta agtatctgga caaggatcag ctcaagctat atacccttat
     2701 ctggaatcgt tttgtggcta gccagatgac agcggccgtt tttgatacca tggctgttaa
     2761 attgtctcaa aaaggggttc aatttgctgc caatggtagt caggttaagt ttgatggtta
     2821 tcttgccatt tataatgatt ctgacaagaa taagatgtta ccggacatgg ttgttggaga
     2881 tgtggtcaaa caggtcaata gcaaaccaga gcaacatttc acccaaccgc ctgcccgtta
     2941 ttctgaagca acactgatta aaaccttaga ggaaaatggg gttggacgtc catcaaccta
     3001 cgcgccaacc attgaaacca ttcagaaacg ttattatgtt cgcctggcag ccaaacgttt
     3061 tgaaccgaca gagttgggag aaattgtcaa taagctcatc gttgaatatt tcccagatat
     3121 cgtaaacgtg accttcacag ctgaaatgga aggtaaactg gatgatgtcg aagttggaaa
     3181 agagcagtgg cgacgggtca ttgatgcctt ttacaaacca ttctctaaag aagttgccaa
     3241 ggctgaagaa gaaatggaaa aaatccagat taaggatgaa ccagctggat ttgactgtga
     3301 agtgtgtggc agtccaatgg tcattaaact tggtcgtttt ggtaaattct acgcttgtag
     3361 caatttccca gattgccgtc atacccaagc aatcgtgaaa gagattggtg ttgagtgtcc
     3421 aagctgtcat cagggacaaa ttattgagcg aaaaaccaag cgtaatcgcc tcttctatgg
     3481 ttgcaatcgc tatccagaat gtgaatttac ctcttgggac aagcctgttg gtcgtgactg
     3541 tccaaaatgt ggcaacttcc tcatggagaa aaaagtccgt ggtggtggca agcaggttgt
     3601 ttgtagcaaa ggcgactacg aggaagaaaa tattaaataa gaggaggggc ccgaaagtaa
     3661 atttcaggct ccttttggtt agaacttgac aaaatacatc attttatgcg aaactagaag
     3721 aagattattt taactaggag aagttatgcg tcttatctat ctgataattg gttttttatc
     3781 actggccttg gctattgttg gggttgtttt acccttgttg ccgacaacgc ctttcctttt
     3841 gttgtctatt gcttgtttct ccagaagttc caagcgtttc gaagactggc tttatcatac
     3901 caagctctat caaacatatg tagctgattt tcgcgagact aagtctatta cgcgtgaacg
     3961 aaagaaaaaa atcatcgtct ctatctacgt cttgatggga atttctattt attttgcacc
     4021 tcttttacca gtcaaaatcg gtctgggtgc tttgaccatc tttatcacct attatctctt
     4081 caaggtcatt ccagacaaag aataattaaa acagtagtta tttcccttga taaaattgaa
     4141 agcatattca taacaatatg atataataaa tttgaagtaa tattcaagga gaatcaaatg
     4201 atttacgaat tttgtgctga aaatgtgacc ttgcttgaaa aagcgatgca ggctggagct
     4261 cgtcggattg aactctgtga taatctagca gttggtggga caacccccag ctatggagtg
     4321 actaaggcag cggttgaact ggcagctaac tacgatacaa ccatcatgac catgattcgg
     4381 ccacgtggtg gtgactttgt ctataatgac ctagaaattg ctatcatgct agaagacatt
     4441 cgtttgactg ctcaggctgg aagtcaaggg gttgtatttg gagttttaac tgctgataaa
     4501 aagttggata agcctaatct ggaaaagtta attgctgcat caaaaggaat ggaaattgtc
     4561 tttcacatgg cctttgatga actaagtgat gaagatcaac cggaagctat tgactggctc
     4621 agtcaagtcg gtgtcactcg tatcctaact cgtgctggtg tgtctggcga ctccttagaa
     4681 aaacgttttg ttcactatca cagaattttg gagtacgcta aaggtaaaat tgaaattcta
     4741 ccaggtgggg ggattgacct tgacaaccgt caaaccttta tcgaccaggt gggggtaaca
     4801 cagttgcatg gtactaaggt tgttttttaa aaaatagaaa ggaactgcta gctttgggta
     4861 gcagttttca cttatgtttg aaatttttaa atcctatcaa tttaatcaag aaaaggctca
     4921 tgattatggt tttatagaaa atagcgaagt ctggacatat agttgccaga ttttgcaagg
     4981 tgactttgtc atgactgtgt ccatcactgc tgataatgtg aactttcaag tctttgacca
     5041 agagactggc gacctctatc ctcacgttta tatggaaagc atgaggggaa gttttgtcgg
     5101 aaatgtccgt gaggcttgtc tggagattct ttaccagatt cggaaggctt gttttgatgt
     5161 gcaagatttt atctgtcatc agactaagcg tatcatgact caagttcagg aaaagtatgg
     5221 aaaccagttg gagtatctgt gggaaaaatc gcctgataca gctgtattgc gccatgaagg
     5281 caatcaaaag tggtatgccg tcttgatgaa aatctcttgg aataagctgg aaaagggcag
     5341 agaaggacaa gtggaagcag tcaacctcaa gcatgaccaa gtagctaatt tactttcaca
     5401 aaaggggatt tatccagcct ttcatatgag caagcgctac tggattagtg tgtcccttga
     5461 tgatacttta tcagatgaag aagtactgga attgatagaa aaaagttgga acttaacctc
     5521 taaaaaatga aatattttaa taattttcat gaactttcaa ttagctaaat attctttact
     5581 gaagaaattt tcagaaaata taggatttac cacactagag gaatatggtg catcttcaaa
     5641 tacctgattg agaatgtcaa gacggatcgt cagatcatct attcgcctca ctgtcatgat
     5701 gacctcggaa tggcagtggc aaatagcctt gctgctgtca agaatggtgc aggacgtgtt
     5761 gaagggacta tcaatggtat tagggagcga gctggaaatg ctgctttgga agaaattgca
     5821 gtggctctca atattcgcca agattactac caagtagaaa ccagtattgt cctaaatgag
     5881 accatcaata cgtcagaaat ggtttctcgc ttctctggta ttccagttcc taaaaacaaa
     5941 gccgtcgttg gtggcaatac cttctcccac gaatctggta ttcaccaaga tggagtcctt
     6001 aaaaatcctc tcacttatga gatcatcaca cctgaattgg ttggtgttaa gattccgctt
     6061 gggtcgccat gcttttgttg agaaactgag agaattggcc ctagatttta cagaagagga
     6121 tatcaaacca ctctttgcta agttcaaggc actggccgat aagaagtaag aaatcacaga
     6181 tgcagatatt cgagctttgg tagctggaag catggttgaa aatccagaag gcttccactt
     6241 tgatgattta caacttcaaa ctcatgcaga taatgacatt gaagcgctcg ttagcctagc
     6301 caatatggat ggtgagaaag tcgaatttaa tgcgacaggg caaggttccg ttgaagcaat
     6361 ctttaatgct atcgataagt tctttaacca atctgttcgt ttggtgtcct acactatcga
     6421 tgcggtaaca gatggaatcg atacccagga tcgggttttg gtcactgttg aaaacagaga
     6481 tacagaaacc atctttaatg cagcagggct tgattttgat gtgttgaagg cttctgctat
     6541 tgtctatata aacgctaata cctttgttca aaaagagaat gcaggtgaga tgggacgcag
     6601 tgtttcttac cacgatatgc ctagtgtgta aaggagaagg ctatggcaaa gaaaatagta
     6661 gctctagtag gagacggaat tggcccagaa atcatggagg ttggtttaga agttctggag
     6721 gctctagctg aaaaaacagg ttttgactat gagattgaca gacgaccgtt cggaggtgca
     6781 gatattgatg cagcatggcc tcccttacct gatgaaaccc ttaaggcaag tagggaagca
     6841 gatgctatcc tactagcaac tatcggtagt cctcagtatg atggagcagt ggttcgccct
     6901 gaacaaggcc tgatgactct ccgtaaggaa cttaatcttt acgctaatat tcgtcctgta
     6961 aaaatctttg acagtctcaa gcatttgtca ccactcaaac tggaacgaat tgctggtgta
     7021 gactttgtcg tggtgcgtga attgacaggc gggatttact ttggagatca tattcttgaa
     7081 gagcgcaatg cgcgtgatat caacgactat agctatgagg aagtggagcg gattattcgc
     7141 aaagcctttg aaattgcaag aaatcgcaga aaaatcctta ctagtatcga taagcaaaat
     7201 gttctagcga cctcaaaact ctggcggaaa gtagctgagg aagtcgcaca ggatttctca
     7261 gatgtaacct tggaacacca gctggtagac tcagctgcta tgcttatgat taccaatcct
     7321 gctaagtttg atgttattgt aacggagaat ctttttggag atattttatc tgatgaatca
     7381 agcgtcttat ctggtacact tggggttatg ccatcagcca gtcattctga aaatggacca
     7441 agtctctatg aacctattca cggttcagta cctgatattg caggtcaagg aattgccaat
     7501 cctatttcca tgattttatc agtttccatg atgttaagag atagtttcgg aggttatgag
     7561 gatgcagagc gtatcaaacg tgctgttgag acaagtttgg cggcaggaat tttaacgaga
     7621 gatataggag gtcaggcttc aacaaaggaa atgacggaag ctattattgc aaggttatga
     7681 agttagacga aaaaattact ctagtccttt tgatttggaa tgtcatcatt ttcttgattt
     7741 atggcattga caaattcaag gcaagaagaa gagcttggcg catcccagag aaaatcttac
     7801 tcattttagc ccttacttgt ggtggttttg gggcctggtt agctggaatc acttttcacc
     7861 acaagactcg aaaatggtac tttaaaacag tttggtttct tgggatggtg accacactag
     7921 tagccttata ttttatttgg aggtaatgga tggcagggtc ttcgagggaa cacgctgctt
     7981 gggctctagc ggactatggt tttaaggtcg tgattgcagg atctttcggt gacattcatt
     8041 acaataatga actcaataat ggcatgttgc caatcgttca gcctagagag gttagagaga
     8101 aactagccca gctaaaacca accgaccagg taactgtgga cttggaacaa caaaaaatca
     8161 tctcaccagt tgaagaattc accttcgaga tagatagcga gtggaaacat aaactcctaa
     8221 atagtttgga tgatatcggt attaccttgc agtatgaaga gttgattgct gcttatgaaa
     8281 aacaacgacc agcctactgg caggattaga aaaaatagaa aaggaaatat agtaaactga
     8341 aataagatgt aaacaaatga attggagctt aacatccatt tccagcaatt ttttagaaac
     8401 tacagtggac tattctggat tcaacacatt ataaaattat gacaaaacac attcacaaga
     8461 aggctacgac attttaaaag gtgagggcgg atgtatcgtt tgccctacta aagttggtta
     8521 cattatcatg accagcgaca aggcaggact tgagcgtaag tttgcagcca aagaaggtaa
     8581 gcgtaacaaa ccaggtgttg ttctctgcgg tagcatggat gaactttgcg ctttagcgca
     8641 actcaaccca aaaattgaag cattctacta aaaacattgg gatgaagata ttcttcttgg
     8701 ttgtatcctt ccttggaaac cagaagcctt tgaaaaactc aaagcatacg gggatggccg
     8761 tgaagaactt atgactgatg tacgtggtac tagctgtttt gttatcaagt ttggaaaagc
     8821 aggtgaacaa ttggctgcca agctttggga agaaggtaaa atggtctacg cctcatatgc
     8881 ttcaatgaca aaacgattga aactcgctat gagagcaagg tgtaatggtg tctatggtcg
     8941 ataaggacgg caaactcatc ccagaacaag gaggagcacg ttcaacctca ccagcaccag
     9001 ttgtgatccg taaagggctt gacattgata aaatcatgat gcacctgtca gacaccttta
     9061 acttatggga ctaccgtcag gttgagtatt attaggatag agaagaagtc tagtgttaag
     9121 gacattacag ctcataatac taggcttttt tatagaaatt cttttctttt tctataggat
     9181 atggtattct atgtagaaaa tatatgttaa taagtaatgc caatatttaa acatcattag
     9241 taaaaggagt tagattgatg aataaaagaa aagttagttt agaagatttt tataaatggt
     9301 atagtctaaa taaagaagag ttattaaata aggcaactgt tggtgaaaag tttaatgata
     9361 aattaaaaga agagtttctc caggaatggc ctttggatag gattttaaca atgtcaatcg
     9421 atgaatatgt aataggaaag ggacagcaaa ataagtcttt atgctacgct cttgagaagg
     9481 gaaaatacaa aaatctattt cttggaattt ctggtggctc agcttcaaaa tttggtattt
     9541 attggaataa aaaaacaaac aaatataaag atcaagctaa taatgagatt tcagagttgg
     9601 atcagcgatt ttcaaaatta aaatcagatt tgtatgaaat tatcaaagaa ggtattcgtt
     9661 ttaactttga aaatcctatt tttgatatga aaagatcaac aaatgaattt attggtcgtt
     9721 ctgctatggt gacaaaatta ctttgtatct attctgaggg agattctttc tttggtgtaa
     9781 atattaatag tcagaaagaa ttttggaacc actttgtttc tcagacaaat caaggtggac
     9841 cttatctgca aaatcataaa ataattgaac tggtgccaaa acttatcctg agttggagcc
     9901 atcgaaatta ggaactatgc tttttgagta ttctaagctt tttatggaaa ataaggaaga
     9961 caatagtaca atggattcat caaacaattt tcgtcatcaa ttaactcaat ctctattaaa
    10021 gtctccaaac cttatccttc gtggtgctcc tggcacagga aagacttatc ttgctaaaga
    10081 aattgccaaa gaattaacgg atggcaacga agaccaaatc ggatttgtac aatttcaccc
    10141 atcatatgat tatacggatt ttgtagaagg tttaagacca gtatcaaatg gggatggagc
    10201 tattgagttt aggctacagg acggtatttt taaagatttt tgtcagaaag caaaagaaac
    10261 ccaattgatt ggaggacaag ataattttga tgaggcttgg gattcttact tagaatatat
    10321 aaatgttgct gaagaaaaag aatatataac aaaaacatct tacttatctg ttaatagtag
    10381 acaaaatttg tcagtaaatt atgatagtgg tgttccagga tggtcactac ctagcaaata
    10441 tgtttacgag ttgtataaag ataaaaatta taataagcaa gaatactaca aaagtggtgg
    10501 aaaaactgtc ctagaaacat tgagaaagag atttggtttg aaagactatg tttccccaac
    10561 agaaattgat actgataaga aattcgtctt catcatcgat gaaatcaatc gtggggagat
    10621 ttctaagatt tttggcgaac tctttttctc tatcgaccct ggctatcgtg gtgaaaaagg
    10681 aagtgtttct acccaatatg caaatctaca cgaaactgat gaaaagttct atatccccga
    10741 aaatgtttac atcatcggaa ctatgaatga tattgatcgt tcagtggata cctttgattt
    10801 tgctatgcgt cgtcgttttc gttttgttga agttactgcc gagggtcaag ttggcatgtt
    10861 ggataaagag ctgaatatcc atgcagaaga agcaaaaatt cgtctaagaa acttgaacgc
    10921 tgctatcgaa aatgttcagg aattaaacag tcattatcat attggaccaa gttattttct
    10981 taagttgaag gatgtagatt ttgactatga attactctgg tccgattata ttaagcctct
    11041 cctagaagac tacttgcgag gttcttatga tgaggttgaa actttggaaa ctttgaaaaa
    11101 agcatttgaa ctgacaaata atgagcaaaa agatcaggca gtagctgatg acaatgaagg
    11161 tgatgaaaac gatgatgcgg attactgata atcaacacaa gattattaaa gaaaaatttg
    11221 ttgaagaata tcctaaacta agcaatcttc ttttagacag aaccttggaa agtctatccc
    11281 aagatgaacg tattttcatt tttccaaatg atttgactca tactcctgat ttggataagg
    11341 accaaaagat ttttgaaaca gtcaatcaga aaatcaagac agggaacgtg attggttttc
    11401 ttggatatgg tcaggaaaga ttaacgattt cctcacgatt ttctgatgag agtaatgacc
    11461 attttttgca ttatctctta aacaaggttc ttcatatcaa tctcactagt ttagatgttg
    11521 ctttgtctcg tgaagagagg ctttatcaac ttttggtgta tctctttccc aagtatctac
    11581 aagctgctat tcgaaaaggt ctttataagg aatatcatcg attttctcat aacgacagta
    11641 atgttaaggg agtgattgat gtaagaagcc atctcaagaa aaatcttcct ttcacgggaa
    11701 atattgccta cgcaacgaga gagttcacct atgataatcc cctcatgcag ttggtccgtc
    11761 acactattga atacattaag aatcagaaaa gcattggtca aggggtacta gataatctct
    11821 caactagtcg tgaaaacgta tctgaaatcg tgcgtgtaac gccctcttat aaactagctg
    11881 atcgtgctaa gattattcgg ggaaatcaat ctaaacctat acgtcatgca tactttcacg
    11941 agtacagaaa cttacaagaa ctttgtctga tgatcctaaa ccaagaaaag cacggtttag
    12001 ggtatcaaga tcaaaaaatc tatggtattc tctttgatgt tgcctggctt tgggaagagt
    12061 atgtttacac cttgttgcca aaaggttttg tacatcccag aaataaggat aagacggatg
    12121 gaatttcagt attttctgtt gggaaacgaa aagtatatcc agatttttat gacagagaac
    12181 gaaagattgt tctagatgca aaatataaaa aactggaatt gactgaaaaa ggaatcaacc
    12241 gtgaggactt attccagctg atttcctatt cttatatttt aaaagctgag aaggctggac
    12301 tgatttttcc tagtatggag cagtcagtaa atagtgaaat aggaaaagta gctggctatg
    12361 gagctcaatt gaagaagtgg tctattcgaa tccctcagaa tgcctcattc tatagtacat
    12421 tttgtaaaat gatggaaaat tcagaagaaa attttaaagc gattattgat gaagaagtgg
    12481 ggagaaaata atttcccctc tttcttttat ttttaacaca agtaaaaccc gaacgatata
    12541 ttttaattca taaaataatt tgacaaaaac tgtactttgg tttataataa attaaggaaa
    12601 cgtcggaaaa ggcgtagtga tgcaagagca taggtaggtc attacaaaag aaacgagaca
    12661 tcgatatgtt aaatgaattt ccaatttttg attacgaaga tattcaattg attccaaata
    12721 aatgtgtcat taaaagccgt gcagaagcgg atacaagtgt cactttagga aatcacacct
    12781 ttaaactacc tgttgtgcca gcgaatatgc agacgatttt ggatgaaaat gtagcagagc
    12841 aactggctaa aggtggttac ttctacatta tgcaccgttt tgatgaggca ggacgcattc
    12901 cttttattaa acgaatgcac gatcaagggc tcattgcttc tatctctgtc ggtgttaagg
    12961 attatgagta tgatttcgtt agacagctca aggctgatgc tcctgagtat atcactattg
    13021 atattgctca tggtcatgcg gatagcgtga tttctatgat tcaacacatc aagaaagaat
    13081 tgccagatac ctttgtcatt gctggaaatg tgggaacacc agaagctgtg cgtgaattgg
    13141 aaaatgctgg tgcggatgct actaaggtcg gaatcggtcc tggtaaggtt tgtatcacca
    13201 aggttaagac tggttttggt acaggtggtt ggcagttggc tgctctacgc tggtgtgcca
    13261 aggctgcgcg taaaccgatt atcgctgatg gaggaattcg tactcacggt gatattgcta
    13321 agtctatccg cttcggtgct agcatgatca tgattggttc cctctttgca ggacacattg
    13381 aaagtccagg gaaaacgatt gaagtcgatg gtgaacagtt caaagaatat tatggttcag
    13441 cctcacaata tcaaaaaggt gcttacaaaa atgtggaagg caaacgtatc ttgcttcctg
    13501 ctaaaggtca tctgcaagac actttaactg agatggaaca agaccttcaa agtgctattt
    13561 cttatgcagg tggacgtcag gttgctgacc ttaaacacgt tgattatgtg atcgtgaaaa
    13621 actccatctg gaatggggat gcttcccact aagacggggt ctttgaccaa aaaacttgtt
    13681 attagagcaa atttctgtta taataaaaca agtttccacc cttagtgtaa tggatatcac
    13741 gtaagattcc ggttcttgag atgggggttc gattccctca gggtggatgt aaacatccta
    13801 aaaagccttt aatagggctt ttttctttat cctgacccaa atttgccgct aaaactgaga
    13861 atctctgtct aaagaattcc caaatgcttt ccagtcccgt tttagagtga ctcagggggc
    13921 tttttttgat ataataaaaa ggactattat cagttagaaa gaggttggta tgaaagaatt
    13981 acaaactgta ctaaagaatc attttgcaat cgaatttgca gacaaaaatt tactggaaac
    14041 tgcctttact catacgagtt atgccaatga gcaccgcctc ttaaaaattt cacacaatga
    14101 acgcttggaa tttttaggag acgctgttct acagttattg atttcagaat atctatataa
    14161 aaaatatcct aaaaagcctg aaggtgacct atcaaaactc cgtgctatga ttgtccgtga
    14221 ggagagttta gctggttttg cgcgtgattg ccagtttaac cagtttatca agttgggtaa
    14281 aggggaagaa aaatcaggtg gtcgcaatcg tgacaccatt cttggtgatg cctttgaagc
    14341 ctttcttggt gcccttcttt tggataagga tgtggccaag gtcaaggaat ttatctatca
    14401 agtcatcatt cctaaggttg aagcaggcga gtttgagatg attacagact ataaaaccca
    14461 tctccaagag ttgcttcagg tcaatggtga tgtggctatt cgttatcagg tgatttctga
    14521 aacagggcct gctcatgata aggtctttga tgtagaagtt cttgttgaag gtaagagcat
    14581 cggtcaaggc caaggtcgtt ctaagaaatt agcagagcag gaagctgcca aaaatgccgt
    14641 tgagaagggg ctggattcat gtatttaaag gaaatcgaaa ttcaggggtt caagtctttt
    14701 gctgataaga ccaaggtcgt ttttgaccaa ggtgtgacgg cagttgttgg acccaatgga
    14761 tctggaaagt ccaatattac agaaagtctg cgttgggctt tgggggagtc tagtgtcaag
    14821 agtctccgtg ggggcaagat gccggatgtc atctttgctg gaaccgaaag tcgcaaaccg
    14881 ctcaattatg cttctgtagt tgtgactctg gataatcatg acggatttat caaggatgca
    14941 ggtcaagaaa tcagggtgga acgccatatc tatcgtagtg gagatagcga atacaagatt
    15001 gacggcaaga aagtccgtct gcgtgatatt catgacctct tcttggatac tggattggga
    15061 cgagattcct tctctattat ttcccaaggg aaggttgagg agatttttaa ttccaagcct
    15121 gaggaacgac gagctatttt tgaagaagct gctggagttt taaaatacaa gactcgcaga
    15181 aaagaaaccg agagtaaact gcagcaaact caggataatc tggaccgctt agaggacatt
    15241 atctacgagt tggataatca aatcaagcct cttgaaaagc aagctgagaa tgcccgtaag
    15301 tttttagact tggaaggaca acgtaaggct atttatttag atgttctggt tgctcaaatc
    15361 aaggaaaata aggctgaact agagtcgaca gaagaagagt tggctcaggt tcaagaactc
    15421 ttgatgagtt attaccaaaa gcgtgaaaaa ttagaagaag aaaatcaaac tcttaaaaag
    15481 caacgccaag atttacaggc tgaaatggcc aaagaccaag gcagtttgat ggatttgacc
    15541 agtctgatta gtgacttaga gagaaaatta gccctatcga aactggaatc tgagcaagta
    15601 gccctcaatc aacaggaagc acaagcccgt ttggctactt tggaggataa gagaagttca
    15661 ctcagccaag aaaaatctga taaagaaagc tctttagccc tcttggaaga aaatctagtc
    15721 caaaataatc aaaaactcaa tcgattagag gctgaattgc tagctttttc agatgatcct
    15781 gatcagatga ttgagctctt acgtgaacgc tttgtggccc ttttacaaga agaagcagat
    15841 gtctcaaacc aactgacccg tattgagaat gagttggaaa atagtcgtca gctttctcaa
    15901 aaacaagcag atcaactaga aaagctgaaa gaacagttgg ctacagctaa agagaaggct
    15961 ggtcagcaaa aggctgagct tgaaactgcc aaggagcagg ttcagaaatt attggccgac
    16021 tatcaagtct gtgctaagga gcaagaggag cagaaaactt cctatcaagc tcaacaaagt
    16081 caactctttg accgtctgga tagtctcaaa aacaagcagg ctagagcgca aagtttggaa
    16141 attatcctga gaaatcatag taacttttat gcaggtgtta agagtgttct ccaagagaaa
    16201 gatcgtctag gtgggattat tggagcagtt agtgagcacc tgacctttga tgtgcattat
    16261 caaactgccc tagagattgc gcttggagcg agtagccaac atatcatcgt ggaagatgaa
    16321 gagtcggcaa ccaaggcgat tgatttactc aaacgaaaca gatctggtcg tgcaaccttc
    16381 cttcctttga ccactatcaa ggctcgtacg atttctagtc agaaccaaga tactattgct
    16441 gcaagtccag gatttctggg catggcagat gagctggtta ctttcgatac tagactggaa
    16501 gccattttca agaatttgct agctacaacg gccatttttg ataccgtgga gcatgcgcgt
    16561 gcagcagcgc gccaggttcg ttatcaggtt cgtatggtga cattggacgg aacagagctg
    16621 cgcacaggtg gttcttatgc aggtggagct aatcgccaga ataacagtat tttcatcaag
    16681 ccagaactgg agcaattaca aaaagaaatt gctgaagaag aagcaagttt gcgttcagat
    16741 gaagtgagtt tgaagaactt gcaagatgag ctagctagat tgacagaaag attagaagcc
    16801 atcaaatctc agggagagca ggctcgtatt caggagcaag gcttgtccct cgcctatcag
    16861 cagaccagtc agcaagttga agagctagaa actctttgga aactccaaga agaggaatta
    16921 aatcgtcttt ctgagggaga atggcaagcg gataaggaaa aatgccaaga gcgccttact
    16981 acaatcacta gtgaaaagaa taatctggaa gctgagattg aagagattaa gtctaataaa
    17041 aacgccatcc aagaacgtta tcaaaacttg caggaagagc tagctcaagc tcgtctactt
    17101 aagacagaac tgcaagggca aaaacgttat gaagttgctg atattgaacg cttaggtaag
    17161 gaactagata atcttgatat tgagcaagaa gaaattcagc gccttcttca agaaaaggtt
    17221 gacaatcttg agaaagttga tacggatttg ctcagtcaac aggctgatga agccaaaact
    17281 caaaaaacaa atctccaaca aggtttgatt cgcaagcagt ttgagttgga tgatattgag
    17341 ggtcaactgg atgatattgc tagtcatttg gatcaggctc gccagcagaa tgaagagtgg
    17401 attcgcaagc aaactcgtgc tgaagccaag aaagaaaagg ttagcgagcg cttgcgccat
    17461 ctacaaagtc aattaacaga ccagtaccag atcagctaca cagaagcttt agaaaaggcg
    17521 catgagttgg aaaatctcaa tctggcagag caagaagtta aggatttaga gaaggctata
    17581 cgctcactgg gtcctgtcaa tttagacgct attgaacagt acgaagaagt tcacaaccgt
    17641 ctggatttcc taaatagcca acgtgatgat attttgtctg cgaaaaacct gctccttgag
    17701 accattacag agatgaatga tgaggtcaag gaacgcttta aatcaacctt tgaggtcatt
    17761 cgtgagtcct ttaaagtgac cttcaagcag atgtttggtg gaggtcaggc tgacctcatt
    17821 ttgactgaag gagacttgct gacagctggg gttgaaattt ctgtccaacc accaggcaag
    17881 aaaatccagt ctcttaatct catgagtggt ggtgaaaaag ccctatcggc tcttgccttg
    17941 ctcttctcca ttattcgtgt caagactatt ccatttgtta tcttggatga ggtggaagct
    18001 gcgctggatg aagccaatgt taaacgtttt ggggattacc tcaaccgctt tgacaaggac
    18061 agccagttca tcgtcgtaac ccaccgtaag ggaaccatgg cagcggctga ttccatctat
    18121 ggagtgacca tgcaagaatc gggtgtttca aagattgttt cagttaagtt aaaagattta
    18181 gaaagtattg aaggatgaca attaaactag tagcaacgga tatggacgga accttcctag
    18241 atgggaatgg acgctttgat atggatcgtc tcaagtctct cttggtttcc tacaaggaaa
    18301 aagggattta ctttgcggta gcttcgggtc ggggatttct gtctctagaa aaattatttg
    18361 ctggtgttcg tgatgacatt attttcatcg cggaaaatgg cagtttggta gagtatcaag
    18421 gtcaggactt gtatgaagcg actatgtctc gtgactttta tctggcaact tttgaaaagc
    18481 tgaaaacttc accttatgta gatatcaata aactgctctt gacgggtaag aagggttcat
    18541 atgttctaga tacggttgat gagacctatt tgaaagtgag tcagcactat aatgaaaata
    18601 tccaaaaagt agcgagtttg gaagatatca cagatgacat tttcaaattt acaaccaact
    18661 tcacagaaga aacgctggaa gatggggagg cttgggtaaa cgaaaacgtt cctggtgtta
    18721 aggccatgac aactggcttt gaatccattg atattgttct ggactatgtc gataagggag
    18781 tggccattgt tgaattagtt aaaaaacttg gtatcacaat ggatcaggtc atggcttttg
    18841 gagacaatct taatgactta catatgatgc aggttgtggg acatcctgta gctcctgaaa
    18901 atgcacgacc tgaaatttta gaattagcaa agactgtgat tggtcaccat aaggaacggt
    18961 cggttatagc ttatatggag ggcttataat ggcagatata aaattgattg cattggactt
    19021 ggacgggacc ttgctgacta ctgataaaag gctgacggat cgtaccaagg aaaccttgca
    19081 agctgcgcgt gatcgtggta tcaaggtcgt attgacaact ggtcgtccct taaaagccat
    19141 ggatttcttt ctccatgagt tagggactga cggtcaggaa gatgagtata ccattacttt
    19201 taatggtgga ttagttcaga aaaatacagg agaaatcctt gataaaacag tcttttcata
    19261 tgatgatgtg gcacgtttgt atgaagaaac agagaaatta tcactgcctc ttgatgccat
    19321 ctcagaagga acagtttatc aaatccaatc ggaccaagaa agtctttatg ccaaattcaa
    19381 tccagctttg acctttgttc cagtggactt tgaagactta tctagtcaaa tgacctacaa
    19441 caaatgcgtg actgcctttg ctcaagaacc cttggatgca gccattcaga agatttctcc
    19501 agaattgttt gaccaatatg aaatctttaa atcacgtgaa atgttgctag aatggtcacc
    19561 aaagaatgtt cataaagcaa caggtttggc aaaactaatc agccatcttg gaatcgacca
    19621 aagtcaagtg atggcttgtg gtgacgaggc caatgacctc tctatgattg aatgggcagg
    19681 tcttggtgtt gctatgcaaa acgctgttcc tgaagtaaag gcagccgcaa atgtagtgac
    19741 gccgatgacc aacgatgagg aagctgtcgc ctgggctatc gaagaatatg tgctaaagga
    19801 gaactaagat atgggattgt ttgaccgtct attcggaaaa aaagaagaac ctaaaatcga
    19861 agaagttgta aaagaagctc tggaaaatct tgatttgtct gaagatgttg atcctacctt
    19921 cacagaagtt gaggaagttt ctcaggaaga agcagaggtt gaaattgttg aacaagctgt
    19981 gttccaagaa gaggaaatcc aagacacagt tgaagaaagt caggattcag agccagctgt
    20041 aggggtttct caagaagaaa tagaagaatt accaaactca gaagaattac cagaggaaga
    20101 gaagcttgag cacgaaggaa ctgtagaaga aaataattct gaagtgcttg aaccagaagc
    20161 tcctcaaaca gaagaaactg ttcaggaaaa atatgaccgc agtcttaaga aaactcgcac
    20221 aggtttcggt gcccgcttga atgccttctt tgctaacttc cgctctgttg acgaagaatt
    20281 tttcgaggaa ctggaagaac tgctgattat gagtgatgtt ggtgtccaag tcgcttctaa
    20341 cttaacggag gaactacgtt acgaagccaa gcttgaaaat gccaagaaac ctgatgtact
    20401 tcgtcgtgtc atcattgaga aattggttga gctttatgaa aaggatggta gctacgatga
    20461 aagcatccac ttccaagata acttgacagt tatgctcttt gttggtgtga atggtgttgg
    20521 gaaaacaact tctatcggaa aactagccca ccgctacaaa caagctggta agaaggtcat
    20581 gctggttgca gcagatacct tccgtgcggg tgcagtagct cagctagctg aatggggccg
    20641 acgagtagat gttccagtag taactggacc tgaaaaagct gatccagcca gcgtggtctt
    20701 tgatggtatg gaacgtgccg tgactgaagg tatcgatatt ctcatgattg atactgctgg
    20761 tcgtctgcaa aataaggata accttatggc tgagttggaa aagattggtc gtattatcaa
    20821 acgtgttgtg ccagaagcac cacatgaaac cttcttggca cttgatgcat caacaggtca
    20881 aaatgcccta gtacaggcca aagaattttc gaaaatcaca cctttaacgg gaattgtttt
    20941 gactaagatt gatggaactg ctcgaggagg tgtggttcta gccattcgtg aagaactcaa
    21001 tattcctgta aaattgattg gttttggtga aaaaatcgat gatattggag agtttaactc
    21061 agaaaacttt atgaaaggtc tcttggaagg tttaatctaa tcagaagcaa aaatcctgca
    21121 aggcataaac ttgcaggaaa tttttttatt ctaagcgacc atcttgacga taggtgatat
    21181 ctggttgcca agtccatttg gcaccgaatt tttcaagtag gtcaaagctg gcttgaggtc
    21241 ccatgcttcc agctttatag tcatgaagtg gggcaccatt ttcagcccag agcttttcaa
    21301 tacggtcaat caacttccat gacgcacaaa cttcatccca gtggctaaag ttagttgagt
    21361 tgttatttag gacatcataa atcaattttt cgtatggttc tggagaagca ccagttgcag
    21421 tcgcatctgt acggtaatca agtgagttag gagccaagtt aaattcttct cctacttgct
    21481 tcccatttag gctaagagag aagccttctg ttggttgaat atagatggtc aaaatatttg
    21541 gagcaagtgg ttctccaaag atagaatcca tttgtttaaa gacgatgttg acatgggttc
    21601 ctttttcagt cagtcgttta cctgtacgga aaaagaaagg aacaccacgg aatcgatcgc
    21661 tgtctacaaa gaaggcacca gatgtaaagg tttcagttgt tgattctgga ttcacatttg
    21721 gctcgctacg ataagagatg tatttcatgc catcaatctt accagagcgg tattgcccac
    21781 ggataaagtg ttctttgagt tcttcatcag ttggatgata gaggttttta aagaccttaa
    21841 tcttttcagc acgaatctcg tcttttgtga agcttgctgg tttgtccatg gcgaggagcg
    21901 aaagaagttg tagagtgtgg ttttggacca tgtcacggag ggcaccggat tggtcatagt
    21961 agccaccacg ttcttctaca cccaagcgct ccgcaaaggt aatttgaaca ttgtcgataa
    22021 aatccttgtt ccaaacgttt tcaaaaatca agtttgcaaa gcgaactgca aagatgcttt
    22081 ggatcatttc cttaccaaga taatggtcga tacggaaaat ttgttcttcg tcaaatgttg
    22141 ctaggagttc gtcattcaac ttgcttgcag ttgcgtaatc tgtaccaaat ggtttttcaa
    22201 cgatcaagcg ctcaaaacct ttgccatcga caatgttttc agatttgagg tgtttggcaa
    22261 tggttccaaa gaactgaggt gccatagaca agaagaagag cttattgtgt tcagcttggt
    22321 atttttcatt aagctcagct tgtaattgac gcaaagcaat ataatgttcc gaatcattga
    22381 catcatggct ttgatagtag aagtggctag caaattcttg ggcttgctcg gtactatctg
    22441 ccaaatcaag gatggactcg acaactacag attcaaaata ttccttactc caaggtctac
    22501 gggcagttcc aataacggca aagtgcttgg aaagattgcc ggattgatat agtctaaaaa
    22561 gggaagggta gagcttgcgt ttagccaggt ctccactcgc accgaaaatt gtaacaataa
    22621 ccttagatga catctagcta cctaatttct atttttattc ctagtcttgc taggtatgag
    22681 gaaacctcat ttcataaact taattctaac ataattttcc gaaaaatcaa aaattccaat
    22741 acgaggtaga aaaactgcaa ggaaatcctt acagtttgag tttagacgtt taagacctta
    22801 tctaagaact ctttcagacg agggtgttgt gggttatcaa agatttggtc aggtgttccg
    22861 tcttcaagga actcgccatc tgcagtaaag ataacgcggt tggcaacctg acgagcaaat
    22921 cccatctcat gggttacgat aatcatggtc atgccttgct cagccaattc cttcataacg
    22981 ttaagtacgt ctccaaccat ctcagggtca agggcagaag ttggttcatc gaagagcatg
    23041 atgtctggat tcattgctag gccacgagcg atggccacac gttgtttttg accacctgat
    23101 aggctatctg gattggcatt agctttatct gctagtccaa ccttttcaag caactccatt
    23161 cccaattcct cagcttcttc cttagtcatc aacttgtgct caataggagc aaaggtgatg
    23221 ttgtccaata cagacatatg agggaagagg ttgaagtgtt ggaataccat gccgatattt
    23281 tcacggacgt ggtcaacatt ggttgttttt tcagttaaat catagccgtt cacagtgatg
    23341 tgaccgctag tgacttcttc taaaagattg aggctacgga ggaaagttga cttaccagaa
    23401 cctgaaggac cgatgataca aacaacatct ccttcataga acttagtcgt aattcctttt
    23461 aggacttcat tttttccata gtgcttgtgt aaatcattta catcaatttt taattttacc
    23521 attaacgaat cctcttttct aagcgtttcg ctagtctagt caaaagtgtg ataattacaa
    23581 gatagaagat agcaaggatt gcatacatct tgaaactttg gtagttacga gcaatgataa
    23641 tcttaccagt ttggaagagt tcaaccaaac cgatagcaga tacgatagtt gtatctttaa
    23701 gagcgataac gaattggttg acaaagtttg gcaacatcaa tttagttgct tgtggcaaga
    23761 taatcttacg catggttttt ccataagaga tacccaagct tcggctggct tccatttggc
    23821 caactggaac ggcctgaata ccaccacgaa cgatttcagc gatataagca gccgcattga
    23881 gtgagagggc aatggttcca gctacaaagt cgttaattgg gctttgttgg cctgtgatag
    23941 actcgatgaa gtttggaatt ccccagaaga tgaaggctgc aagaatcatc aatggaatac
    24001 cacgaataac gtcaacgaaa atctcagaga tgacgcgaag agatttgtat gggctaacgc
    24061 taaacatacc gaagataatt ccgatgacaa tggcaatagc aaatgagata agagctagag
    24121 caagagtgat accaagaccg ctaaggagtt gtttgtagtt gttttgaagc aagccccaga
    24181 gcgttgtttc gtcaacagta cttgttgaag cagttgaaga ttcgctagct aggtatttgt
    24241 caagaatctt ttggaattca ccgtttgctt taaggtttgc aagtccgttg ttgaacattt
    24301 caatcagttc tggatttgct ccttttttaa cggcaaaggc tgtttcaccg attggagttc
    24361 cagagattgg agttttcaat ttttgacctt ggctgataga atatttgaga acaggttcat
    24421 catccataac ggcatcaatg gcaccagtgt ttaaactgtc atacattgaa gaaccatcag
    24481 caaaggtttt gattttgtag ccgtatttgc tttgattttc tgttaggaag gtttgagaag
    24541 cagttccgtt tttaacaccg actgtctttc cttttagatc ttcataagaa gcaatattgc
    24601 ttgattcttt gacaccaaga atggtattag cagtgtagta tgattctgag aagtcaaaag
    24661 ttgccttacg agcatctgtg acagacatac cagcgatgat accatcggct tgaccagctt
    24721 ggacagcact gatagcagca tcaaaaccag ggttggtgat ttcaatttca aaaccttggt
    24781 ctttagcgat tgccttaatc aattccatat caataccagt gtattggttg cttgaatttt
    24841 ggaaaacaaa aggtgcaaaa gaagaatcgc tggcaatgat atatttagcc ttaacaggaa
    24901 tagcttttaa tcctgcgaga gtagttgtag ttggcactgc tgaagatgat gaagcagtcc
    24961 atttcttgat aattttatca agactaccat cttttttcat ttcagacaag gcttggttaa
    25021 attcagtaac caggtgctcg tatttacttc cttttttcac accgaaagca aaacttccta
    25081 cagcttcacc atccatttca atatggaggt cttgaccttg gttaatggca tattcgataa
    25141 caggtttgtc atccatcatg gcatcgatgg caccagcact caagctgttg ttcattaaat
    25201 caccagtgtc aaatgtttta atagtaaagc cgtatttatc tttgattgtt tcaaggaaac
    25261 gttgagcggc agttccgttt ttaacaccaa cggttttgcc agttaattgg tcgtacttgc
    25321 taattttgtg tgactttgta gtagcaatga caacttttgt atcatagtaa gtatcagaca
    25381 tggtgaagac tttttcacgt tctttagtct ttgtcatccc tgccatgata gcgtcggctt
    25441 gcccagcttg aaccgcattg actgctgcgt caaatccagg ataggacatc tgaatgttcc
    25501 agcctttaat ctcagcgact ttgttaataa tgtcaacatc aattccttta taagtttgat
    25561 ctgaatcttt aaactcaaaa ggtgcatagg cggtatcaga aacaatctta atcgtttctg
    25621 ctttggcaat acctaatgag aaaattggga ataaaattag caaaaatgct agaaattttt
    25681 tcttcatttt tagtctcctt ttccgaatat tctctcatta tatcagaaaa agtaaaaaaa
    25741 ggcaaatttt tatatttttc gtgtcagaaa atataacatc gattttttcc tttccttgaa
    25801 ttgctattaa aaagtgctat aataatagta tatatagaag aaaagaggac ggggatatga
    25861 agaacaaaag aatatttaaa gacttccaag cttcaaaaat gagtttaaac atttacacaa
    25921 gccccttgtt agcctttgtt tttgtcttca taggagagtt tgtggctttt actttgtatg
    25981 gtattggctt gttagctctc atcggacttg ctagaaattt tggagaggct ggtcaaaatc
    26041 ttgcaagcta cttgcagacc ttgcatcaga gcttgacgga taaaacaagt gactttcgtt
    26101 taattttagg attactggcc tttggtttta ttcttaacac tgtgttcaga tggacaagaa
    26161 aagttgagaa aagacctatt cgaaccttgg gattttatag agagaatttc ctcagcaatc
    26221 ttctgaaagg atttagtcta ggcctggcac tttttcttct gaccttgtta ggtttagtgg
    26281 tcttaggtca atatcgtttg gaatccattc acttgaatcc ttattctctt gcctttgtcg
    26341 tctttactat cccattttgg attttacagg ggacagcaga agaagtggtg gcccgtgctt
    26401 ggctacttcc tcaattggcc tcaagaacca atctaaaact agctattctt atatctagcc
    26461 tgttctttac cctgcttcat atgggcaatt ctggtctcac ccctctatct ctagtaaatc
    26521 tctttttatt cggagttgcc atggctcttt accttctcaa aactgataca gtttggggtg
    26581 ttgcaggtat tcatggtgct tggaattttg ctcagggtaa tctctttggg attttagtta
    26641 gtggtcaacc gtcaggaacg tctctgatga cctttttacc acaaggcaat caagattggc
    26701 tatcaggtgg ttcttttggc atagaaggtt ccattatgac aagtctggta ttactactgc
    26761 tgattgtcta tcttgctaat aaattaaaga aagaaaatga aaggatgtga cttcggtccg
    26821 tccttttctt cgtgaaaata ctataagtat gctaaaatag gaatagcaca tggagagagg
    26881 attcttatga tcaatcacat tacagataat caatttaaac tagtatcaaa atatcaacca
    26941 tcaggagatc aaccccaagc tatcgagcag ttggtggata acattgaggg gggagaaaaa
    27001 gctcagattc tgatgggggc gactggaaca gggaagacct atactatgag tcaggtcatt
    27061 tctaaagtca ataaaccaac tctggttatt gcccacaata aaactctggc tggtcagctc
    27121 tatggggagt ttaaggaatt tttccctgaa aatgcagttg agtatttcgt atcctactat
    27181 gattattacc agccagaggc ctatgtccct tctagcgata cctatattga gaaggatagt
    27241 tctgtcaatg acgagattga caagcttcgc cactcagcta cctcagccct tttggagcgt
    27301 aatgatgtta ttgtcgtggc ctcagtctct tgtatctatg gtttgggttc gcccaaggaa
    27361 tacgctgata gtgtcgttag tctccgtcct ggtctagaga tttctcgtga taaactcttg
    27421 aatgacttgg tcgatattca gtttgaacgt aatgatattg atttccaacg cggaagattt
    27481 cgcgttcgtg gggatgtggt agagattttc ccagcttccc gagatgaaca tgcctttcga
    27541 gtagaatttt ttggagacga aattgaccgt attcgtgaag ttgaggctct gacaggtcag
    27601 gtgttgggag aagtggatca tttagcgatt ttcccagcga cacactttgt gaccaatgac
    27661 gaccacatgg aagttgccat tgcaaagatt caggccgagt tggaagaaca attagctgtc
    27721 tttgaaaagg aaggtaaact gcttgaagcc cagcgtttga aacagcggac agagtatgat
    27781 atcgaaatgt tgcgtgagat gggctatacc aatggggttg aaaattattc tcgccacatg
    27841 gatggacgga gcgaaggaga gcctccttat acgcttctcg acttcttccc agatgatttc
    27901 ttgattatga ttgacgagag tcatatgacc atagggcaaa tcaagggcat gtacaatgga
    27961 gaccgttcgc gtaaagaaat gctggttaat tatggtttcc gtttgccgtc tgctttggac
    28021 aatcgtcctc tccgtcggga ggagtttgag agtcacgttc atcagattgt ttacgtttca
    28081 gcgacacctg gtgactatga aaatgaacag accgagacag tgattgagca aatcattcgt
    28141 ccaacgggac tcttggatcc agaggtggaa gtccgtccga ctatgggaca gattgatgac
    28201 ctcttgggtg aaatcaatgc ccgcgttgaa aaaaatgagc gtacctttat cacaactttg
    28261 accaagaaaa tggcagagga tttgaccgac tacttcaagg aaatgggtat caaggtcaag
    28321 tacatgcact cggatatcaa gaccttggaa cggacggaga ttatccgtga cctgcgcttg
    28381 ggtgtctttg atgtcttggt cggaattaac ctgctccgtg aaggaattga cgttcctgaa
    28441 gtgagcctcg tagctattct cgatgctgac aaggaaggtt tccttcgcaa cgaacgtgga
    28501 ctcatccaga ctattggacg tgctgctcgt aacagtgaag gccatgtcat catgtatgca
    28561 gacacggtta cccagtctat gcaacgtgct atcgatgaaa ctgcccgccg tcggaaaatt
    28621 cagatggcct ataatgaaga gcatggtatc gtaccacaga caatcaagaa agaaatccgt
    28681 gacctgattg ccgtgaccaa ggcagttgct aaggaagagg acaaggaagt cgacatcaat
    28741 agcctcaaca aacaagagcg caaagaactc gtcaagaaac tagaaaaaca aatgcaagaa
    28801 gccgtcgaag tgcttgactt tgaactggcg gctcagatcc gtgatatgat gttggaagtc
    28861 aaggccttgg attaggggaa tagtatgatt tatttaagaa agttaaagag agaagatttg
    28921 atgtctttat gggaaatggc ttattcacaa cttaatccag tttggaaaca gtatgatgct
    28981 ccctattatg atgattatca gtatttttca aattttaaag aattcgaact acaaaaatca
    29041 gaatccattt taagcaactc aaatcgcctt ggtatttttg ttgatgataa actagttggg
    29101 actgtttcgc gttattgggt atgtaaacaa acaagatgga tggaattggg aattggtatt
    29161 tatgataaaa aattctggaa cactggtatt gggaaagttg ctatgttgca gtggatagat
    29221 aggacgtttc aggattactt ggagttggag catctgggtt tgacaacttg gtcagggaat
    29281 attggtatga tgaaacttgc tgaaaaatta agaatgaaaa aagaagctca tattccaaaa
    29341 gttcgttatt atcaaggtaa atattttgat agtattaaat atggtatttt gagagaagac
    29401 tgggagaaaa taaatgacgg ttattatcaa atcaatggaa actcctaaag agatagaagg
    29461 taaatccctt gttcactggc aaacgtggag agagtcttat gatgaccttt tgcctgcgga
    29521 atttcaggat acaatgacat tagaaagatg tcgattcttt agtcaaaagt atccagaaaa
    29581 tacattgatt gcgatggatg gcgtgaaggt ggttggtttt atcagttatg gcaattttcg
    29641 tgatgagact attcaagctg gtgaaattat tgctttatat gttttaaaag actattatgg
    29701 aaaaggtatc gcacaaaagt taatgaaagc agctttgact gctcttaatc atttttctga
    29761 aattttctta tgggtattga aagataacaa gcgcgccatt gctttctatc aaaaaatggg
    29821 ttttactttt gatggacaag aaaaaatact tgaacttgga aagcctataa aggaaaaacg
    29881 aatggtgttc tattctaaat aattttaaaa aagtaaaaga taatatctct ggtagtaagt
    29941 ctgaaaattt aataaattag aaagcgagta aatttatgtc ccgttcccaa ttaacaattt
    30001 taacaaatat ctgtctgatt gaagacctcg aaactcagcg cgtggtgatg cagtatcgcg
    30061 cccctgaaaa caatcgctgg tctggttatg cctttcctgg aggtcatgta gaaaatgatg
    30121 aggcttttgc ggagtctgtc attcgtgaaa tctacgaaga aacagggttg actatccaaa
    30181 atcctcaact tgtcggcatt aaaaattggc cactagatac aggtgggcgc tatattgtca
    30241 tttgttataa ggcgactgag ttctctggta cccttcaatc ttcagaagag ggagaagttt
    30301 cttgggtgca aaaagaccag attccaaact taaatctggc ctatgatatg ctaccattga
    30361 tggaaatgat ggaagctccc gacaagtcag agtttttcta tcctcgccgt acagaagacg
    30421 attgggaaaa gaaaatcttc tagtctttta ctaaataacc tagctgatcc aaggcctcct
    30481 cgatatagtg gaggtcttgt tgtgtttcgg cttcgactag gtggtaatgg atgccatctg
    30541 tcaattcaga tagaggtcta aagtcagaat gctcgacttg ttctagaaaa tgttgcacat
    30601 ctctgcgaca agacagttta agcaaggttt caatttctcc ataaacggga tggtcaatca
    30661 aggtattctg gacatgccca ccattatcga caatagcaag gagttcctga ccgatttctt
    30721 caacttcatg tttcactttg aaaagtttgt gaacataagg attggtatca atttgcttat
    30781 agatgtagcc acgattggtg gataggatag gagcgccatc ggctctcaaa attgcaatgt
    30841 cctgcacaat gacctgacgt gtgacatgaa aatgttccgc caaactttgg ccattaaggg
    30901 ctttaggagc ttctttcaag agttggagca gggcttgttt gcgatctttt gtcatagctt
    30961 ttccttttaa cggcgttttc gaagcacttt atagacagct agtgctaatg tatagtctac
    31021 catactatgg ataattgtgc caaatccaac tagtacaaat agaacataga acatattttc
    31081 tacattggta cccgaagttg cgtaaaaaag gacacaggct aatacttcag caagggcatg
    31141 aacaacagcc aaaacaaaat tgaaaaccca ggaagatttt ggtttatcta gggtatcggg
    31201 gaatttttgt aggtaaagag ctcctaaagc accaaaagat atatgggaaa aagcccgaaa
    31261 aacgataacc atgggatagc cagccatcaa aaatccaaaa ctagaggcta ggatgacaaa
    31321 aactgccatc aagggcgaca agaacatggc tataaaaata gcgatgtggc tccccaaagt
    31381 ataggaagca ggtggaatga caatcttgaa aggcataaca attggaatca aaatcgcaat
    31441 agccgttaaa agggctgtca ttgtcataaa ttgtgtcttt ttccgtgtat tcacaagaat
    31501 ctccttttta actgcatata cactagtatg gtacaataaa ccagacaata aagcaagaat
    31561 ttacttgggt ttatagatca ttttttagtt aaaagttata gtagattgaa actagaatag
    31621 tccacctcta cttctaaaac attgttagaa atcgatttga ctgtcctgat cgatttgtcc
    31681 tgttcttatt tcgttttact atagtaaaga tttcattaaa aagaaactgt atagagcaaa
    31741 atctccacct tcaggtttga aagcggagat tgtttttatt ttttcaaggt ttgtagtcgt
    31801 ggaacaatgg ctagggttag aattgcagaa atgaccaatt cagcaattga atttgttgag
    31861 ataacggttg ccagaagaag ttggatattt ccattataaa catttccaaa taggaagaag
    31921 attcctccaa ggacaaagat agtatttgtc aaggaaccaa gagccccagc taaaatcaga
    31981 ccagtcttgt ttttcatcag tttatagact aagtaaggag ttaaaccaat caaaatacgt
    32041 gggacaatgg caatgatagc tgagtagatg tttccgtttg gtacgaaggg agagaagagg
    32101 tagcttgtcg gtagaatcgt aatcgtgtta accgtcaagc taagtaatcc catcaaaaat
    32161 ccaagtgtaa ccccaactcg tggaccataa ataatgctgg caataatgac aggaatatga
    32221 acaatggtcg gtttgattgg aaatggaaaa aggttaaaga taagtgagct cagaaagtgt
    32281 atcacgagca tggtagcaaa aaagatagca atgggtgcaa tattagagcg ttttttcatc
    32341 gatagtttcc tttattcttt ctaaaataat tgtgaggtca gctaaagctc ctcgtccgtg
    32401 gtctccacaa gctagtaggg attccttagg agcaatcagc tgatagccgt aggtttctaa
    32461 tgttttcaga ttattctgag ttactggatg gtcatacatt tttgtattca tagcaggagc
    32521 tattagtttg ggaatatgac ttggtagggc tagagctgta ctggttacca tgttgtccgc
    32581 aaatccgtga gctagttttg caatagtgtt agcagttgca ggtaccacga taaataaatc
    32641 tgcttttttt ccaagttcga tatgattgac ctgatcagga tagggttctt tcatgacatc
    32701 caagtggaca ggattctgtg agagtacctg tagtgtcaaa ggttggataa actctgtagc
    32761 agcctgagtc attaagacag tgacttgatg gccttgtttt tttagagaac tgactaaatc
    32821 tgccgactta taagaggcga ttgaacccgt tacagccaag agaatgtttg ccatagtttt
    32881 cctttctaag aatgataggc ttgaattttt tcaaggagga gttctgcaat ttcttcttta
    32941 gtctggactg tttgaagctg atttttctca acaaatatag ctcggtgctg acctgctgaa
    33001 atttgagtca ggtcattcgc gatgattaaa tctgcttgat tcttgataag actttttcgt
    33061 gcaatgtcaa ccagatgatc ttcggtaaca tcaaccagca gtttgaaacc aatcagatga
    33121 atagtaggat tccattcctt gactagggat atgattttgg gtgtcttttt aaggaacaaa
    33181 acctgaacct catcagttga agaaatcttg gcctgatgat tctgcttgct taaaaattct
    33241 tttagattgg agctagcctg aacttcctca agccctgtca tataaacagg agtgtagtca
    33301 gaaacagcca ttgagtggat caagacctga taatcctgaa cacgttcttg catttctatt
    33361 agaaggtcct tggtattggt aatttctcga atacttaggt taggatgagg ctctggcttc
    33421 agagctcgtt ttgtcgtaat taaacaaact tcatgccctg cagaaagcaa agtctctgtg
    33481 ataattttcc ccaagtgacc tgtagaatgg ttagtgatag agcggacgct atcgatagct
    33541 tcactggtac cgcccgatgt aactaaaatt ttcatagcac tattgtacac aaaaataagc
    33601 ggtaagtaaa atgaaagtga taaatttttg gtaaaaacga agatttacta tagtttcaaa
    33661 ctataaagcc atataaaatt taagaaagga ctctaaaagt cttaaaaaca gagatattta
    33721 cgaacgttta gagagtttta agatgttaaa aatcttgttt tgtgatataa tgaattatca
    33781 tataagaggt tagaggaatt ttgaatgaaa acagatattg aaatcgcaca gagtattgag
    33841 ttgaagccaa ttgttgatgt tgtagagaaa cttggtattt cttacgacga tttggagttg
    33901 tacggaaagt acaaggctaa actcagcttt gataaaattc gggcagttga gagcaatcca
    33961 gtcggtaaat tgatcttggt tactgccatc aacccaacac ctgcaggtga aggaaagtcg
    34021 acgcttacca ttggtcttgc ggatgccttg aacaagattg gcaagaaaac catgattgct
    34081 atccgcgaac cgtctcttgg tccagtcatg gggatcaagg gtggtgctgc tggtggtggg
    34141 tatgcacaag ttctgccaat ggaagacatc aacctccact ttactggaga tatgcatgct
    34201 attacaactg ccaacaatgc cctttctgcc ttgattgaca accacttgca ccaagggaat
    34261 gagctgggaa ttgatcaacg tcgtatcctc tggaaacgcg ttgtggactt gaacgaccgt
    34321 gcgctccgcc atgtgactgt tggtcttggt ggtcctctaa acggtattcc acgtgaggat
    34381 ggttttgata ttacagttgc ttcagaaatc atggcaattc tttgcttggc aacggacatc
    34441 gaggacttga aacgtcgttt ggcgaatatc gttattggtt atcgctatga ccgtacgcct
    34501 gtttctgtag gtgatttgca ggttgagggt gccttggctt tgattttgaa ggatgctatt
    34561 aagccaaact tggttcagac aatttacggt acacctgcct ttgtacacgg tggtccattt
    34621 gccaatatcg ctcatggctg taactctgtt ttggcgacga caacagccct tcacttggct
    34681 gattacactg ttactgaagc tggttttggt gcggaccttg gtgctgagaa attccttgat
    34741 atcaagacac caaacttgcc aacatctcca gatgcagttg ttattgtcgc aacccttcgt
    34801 gcccttaaga tgaatggtgg tgtggctaaa gacgctctga ctgaagaaaa tgtagaggca
    34861 gttcgtgcag gttttgctaa cttgaaacgc cacgttgaaa atatccgtaa gttcggtatt
    34921 ccagcagttg tagctattaa cgaatttgta tctgatacag aagctgaaat tgcagtctta
    34981 aaagaactct gtgcctcaat cgatgtacca gttgaattgg ctagtgtctg ggctgatgga
    35041 gcagaaggtg gagtagcact tgccgaaaca gttgttaaga caattgctga aaatccagct
    35101 aactataaac gtttgtacga taatgacctt tctgtccaag aaaagattga aaaaattgtc
    35161 actgaaatct atcgtggtag caaagtgaac tttgagaaga aatctcaaac acaaattgct
    35221 caaatcgttc aaaacggttg ggacaaattg ccaatctgta tggctaaaac tcaatacagt
    35281 ttctcagaca atccaaatgc gcttggagca ccagaaaact ttgaaattac cattcgtgaa
    35341 ttggtaccaa aattaggtgc aggcttcatc gttgccttaa ctggtgatgt tatgaccatg
    35401 ccaggtcttc caaaacgtcc agcagctctc aacatggatg ttgaaagcga tggaactgta
    35461 ctaggcttgt tctagtggat tgaaattgac tttaagtgag tttggaaata atatccaagc
    35521 tcattttttc tcagactgca agcagttcat caataagatt tatactcttc gaaaatctct
    35581 tcaaactacg tcagcttcac cttgccgtag gtatatgata ctgactctgt cagttctatc
    35641 cacaacctca aaacagtgtt ttgagcaacc tgcggctagc ttcctagttt gctctttgat
    35701 tttcattgag tataagtaga tagaaaagtt atatactatc tattgaaaat attataaatc
    35761 agatacaaag acaggtgaaa ccttctgtgt tatactagag atatgttaga tttgaaagaa
    35821 tacggtatcg tcatgtggcc ggaggagaaa gtcatttctt tccgtgagaa acttctcgct
    35881 tggtatgatg aaaacaaaag agatttgcct tggaggagaa gtaaaaatcc ttatcacatc
    35941 tgggtatctg aaatcatgct tcagcagacc agggtggata cagttatccc ttactacgaa
    36001 agattcctgg actggtttcc aactgtcgaa agtctggcaa ctgcgcctga ggagagttta
    36061 ctgaaagctt gggagggctt gggctattat tctcgagttc gcaatatgca ggctgcagcc
    36121 cagcagatta tgactgactt tggtggccaa tttccaaata cctatgaagg aatttccagc
    36181 ttgaaaggga ttggacctta cacagcagga gccatttcca gtattgcttt taacttgcct
    36241 gagccagctg tagatggtaa tgtcatgcgg gtcttggcgc gtctgtttga agtcaaccac
    36301 gatattggga ttccaagtaa tcgaaaaatt tttcaggcaa tgatggagat cttgattaat
    36361 ccggatcgtc cgggtgattt taatcaagcc ttgatggact tagggtctga tattgagtct
    36421 cctgtaaatc ccagacctga agaaagccca gtcaaggact ttagtgcggc atatcagaat
    36481 ggaaccatgg accgttatcc aattaaatct cctaagaaaa agccggttcc tatttatctt
    36541 aaagccttag ttgtgaaaaa ttctcaagga caatttttac ttgaaaaaaa tgaaagcgaa
    36601 aagctcttgg caggtttttg gcatttcccc tttatagaag ttgataactt ttcgcaagaa
    36661 gagcagtttg acctctttca tcaggttgcg gaagaaagtg tgaactttgg ccccagtcca
    36721 gaagagagtt tccagcagga ctatgaccta gatgttgatt ggcttgatgt ttgttttgat
    36781 acagtccagc atgtttttag tcatcgaaaa tggcatgtac agattgtagc aggtcaggtg
    36841 agtgacttcc atgatttttc agatagggaa gttcgttggc tttcaccaga agaattcaag
    36901 aattacccac ttgccaaacc ccaacaaaaa atctggcagg cttatgcaca agccaactta
    36961 gacagtagcc aagactagct attgtgtctt ctgactattt tttggtataa tagtagagaa
    37021 aaaggtgaac atatgaaaaa aatactaatt gtagatgatg agaaaccaat ctcggatatt
    37081 atcaagttta atatgaccaa ggaaggttat gaagttgtaa ctgcttttaa tggtcgtgaa
    37141 gcgctagagc aatttgaagc agagcaacca gatattatta ttctggattt gatgcttcca
    37201 gaaattgatg gtttagaagt tgctaagacc attcgtaaga caagcagtgt gcccattctt
    37261 atgctttcag ccaaagatag tgaatttgat aaggttatcg gtttggaact tggggcagat
    37321 gactatgtaa cgaaaccctt ctccaatcgt gagttgcagg cgcgtgttaa agctcttctg
    37381 cgtcgttctc aacctatgcc agtagatggt caggaagcag atagtaaacc tcaacctatc
    37441 caaattgggg atttagaaat tgttccagac gcctacgtgg ctaaaaaata tggcgaagaa
    37501 ctagacttaa cccatcgtga atttgagctt ttgtatcatt tagcatcgca tacaggtcaa
    37561 gtcatcacgc gcgaacactt gcttgagact gtctggggtt atgactattt tggtgatgtc
    37621 cgcacagttg atgtgactgt acgacgtctg cgtgagaaga ttgaagatac gcccagccga
    37681 ccagagtata tcttgacgcg ccgtggtgta gggtattaca tgagaaataa tgcttgattt
    37741 actgaaacaa accattttta ccagagattt tatctttatc ctgattttgt taggtttcat
    37801 ccttgttgtg accctcttat tactggaaaa tagacgtgat aatattcagt tgaagcaaat
    37861 caatcaaaag gttaaagatt tgattgcagg agattattcc aaggttcttg atatgcaagg
    37921 tgggtctgaa atcaccaata ttaccaataa tttgaatgac ttgtcggagg ttattcgtct
    37981 cactcaggaa aatctagaac aagagagtaa gaggctaaat agtattctgt tttatatgac
    38041 agatggggtt cttgcgacta accgtcgggg tcagattatc atgattaacg atacagccaa
    38101 gaagcaactg gggttggtta aggaagatgt tctgaataga agcattttgg aattgctcaa
    38161 gatagaagaa aactatgaat tgcgtgattt gattacccaa agtccagaat tgttgctaga
    38221 ttcccaagat atcaatggcg aatatttgaa ccttcgagtt cgctttgcct tgatacgtcg
    38281 agagtctggc tttatttcag gtttggtggc tgttttgcat gatacgacgg agcaggagaa
    38341 ggaagaacgc gaacgaagac tctttgtttc caatgttagc catgagttac ggactcctct
    38401 gactagcgta aaatcctatc ttgaagcctt ggatgagggg gctttgtgtg aaactgtagc
    38461 accagacttt atcaaggttt ctcttgatga gaccaaccgt atgatgcgca tggtgacgga
    38521 tctcctccat ctttcacgta ttgataatgc taccagtcac ctagatgtgg aactgattaa
    38581 cttcactgct tttattacct ttatcctcaa tcgttttgac aagatgaaag gacaggaaaa
    38641 ggagaaaaaa tatgagctgg tgagagatta tcccatcaat tctatctgga tggaaattga
    38701 tacagataag atgacgcagg ttgtcgacaa tattttaaat aatgctatta agtattcgcc
    38761 agatgggggt aaaatcactg tcagaatgaa gacaactgaa gaccagatga ttttatccat
    38821 ttctgaccac ggtttgggga ttcctaagca ggatttacca cgtatctttg accgtttcta
    38881 tcgtgtggat cgtgctagaa gtcgtgcaca aggtggtaca ggtctaggac tgtctatcgc
    38941 taaagaaatt atcaaacaac ataagggctt tatttgggcc aagagtgaat acggcaaggg
    39001 ttcaaccttt accattgtac tcccttatga taaggatgca gtgaaagaag aagtatggga
    39061 ggatgaagta gaagactaga atgagtgaaa taggctttaa atacagtatt ttagcgtcgg
    39121 gttccagtgg aaattctttt tatctggaaa cctcaaaaaa gaagctttta gtagatgcag
    39181 gcttgtctgg caagaaaatt accagtctgc tagctgaaat taaccgtaag ccagaagacc
    39241 tggatgccat cttgattacc catgagcatt cagatcatat ccatggagta ggcgttttgg
    39301 ctcgcaagta tggtatggat ctttatgcca atgaaaagac ctggcaagct atggaaaata
    39361 gtaaatatct tggcaaggtg gattcttcgc aaaagcatat ttttgaaatg ggtaaaacca
    39421 aaacctttgg agatatcgac atcgagagtt ttggtgtaag ccatgatgca gtcgcaccgc
    39481 agttctatcg ctttatgaag gatgataaga gttttgtcct cttgacagat acaggttatg
    39541 tcagtgaccg tatggcgggc attgtcgaaa atgcggatgg ttatcttatc gaggccaacc
    39601 atgatgtaga gattttgcga tcaggttctt acgcttggcg actcaaacaa cgaatcctat
    39661 ctgaccttgg tcacctttct aacgaggacg gtgctgaagc tatgattcgg acgctaggaa
    39721 atcgtactaa gaagatttac cttgggcatt tatctaagga aaacaatatc aaggaactgg
    39781 ctcatatgac catggtcaat cagctggctc aagctgatct gggagtcgga gtagacttta
    39841 aggtttatga tacctcacca gataccgcaa caccattgac agagatatag aaagaacgct
    39901 gagaaggtgt tcttttt
//
LOCUS       DAVKMJ010000020        37765 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000020 DAVKMJ010000000
VERSION     DAVKMJ010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37765
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.020"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(180..986)
                     /gene="yidA"
                     /locus_tag="VW348_001051"
     CDS             complement(180..986)
                     /gene="yidA"
                     /locus_tag="VW348_001051"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEU9745963.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDEGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMADKEIVKCMFIDEPE
                     ILDATIEKIPAEFYERYSINKSAPFYLELLTKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(999..2303)
                     /locus_tag="VW348_001052"
     CDS             complement(999..2303)
                     /locus_tag="VW348_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU9745964.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSHRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            2375..2752
                     /locus_tag="VW348_001053"
     CDS             2375..2752
                     /locus_tag="VW348_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEU9745965.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELMMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSRYQVDGQKIE
                     LAYQLQNQEGHPFASYQLEITWG"
     gene            2842..3174
                     /locus_tag="VW348_001054"
     CDS             2842..3174
                     /locus_tag="VW348_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEU9745966.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            3186..4757
                     /gene="ffh"
                     /locus_tag="VW348_001055"
     CDS             3186..4757
                     /gene="ffh"
                     /locus_tag="VW348_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEU9745967.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(4952..6235)
                     /locus_tag="VW348_001056"
     CDS             complement(4952..6235)
                     /locus_tag="VW348_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEU9745968.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMLATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLEANWFE
                     IPGFYLPFSTSGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLIGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(6489..7202)
                     /gene="rsmG"
                     /locus_tag="VW348_001057"
     CDS             complement(6489..7202)
                     /gene="rsmG"
                     /locus_tag="VW348_001057"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEU9745969.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            7296..7856
                     /locus_tag="VW348_001058"
     CDS             7296..7856
                     /locus_tag="VW348_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEU9745970.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            7858..8757
                     /gene="htpX"
                     /locus_tag="VW348_001059"
     CDS             7858..8757
                     /gene="htpX"
                     /locus_tag="VW348_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEU9745971.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(8906..10465)
                     /locus_tag="VW348_001060"
     CDS             complement(8906..10465)
                     /locus_tag="VW348_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9745972.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEICSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(10704..11021)
                     /locus_tag="VW348_001061"
     CDS             complement(10704..11021)
                     /locus_tag="VW348_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU9745973.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FGF"
     gene            11191..11733
                     /locus_tag="VW348_001062"
     CDS             11191..11733
                     /locus_tag="VW348_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEU9745974.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENEALDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            11733..12362
                     /gene="nth"
                     /locus_tag="VW348_001063"
     CDS             11733..12362
                     /gene="nth"
                     /locus_tag="VW348_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEU9745975.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            12573..13094
                     /gene="pyrR"
                     /locus_tag="VW348_001064"
     CDS             12573..13094
                     /gene="pyrR"
                     /locus_tag="VW348_001064"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEU9745976.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            13113..14036
                     /locus_tag="VW348_001065"
     CDS             13113..14036
                     /locus_tag="VW348_001065"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEU9745977.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            14086..15165
                     /gene="carA"
                     /locus_tag="VW348_001066"
     CDS             14086..15165
                     /gene="carA"
                     /locus_tag="VW348_001066"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEU9745978.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            15478..18654
                     /gene="carB"
                     /locus_tag="VW348_001067"
     CDS             15478..18654
                     /gene="carB"
                     /locus_tag="VW348_001067"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEU9745979.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKEGPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDTLIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIKSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     regulatory      complement(18870..18958)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(19167..19796)
                     /locus_tag="VW348_001068"
     CDS             complement(19167..19796)
                     /locus_tag="VW348_001068"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU9745980.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGAITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(19798..20580)
                     /gene="thiM"
                     /locus_tag="VW348_001069"
     CDS             complement(19798..20580)
                     /gene="thiM"
                     /locus_tag="VW348_001069"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU9745981.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEIAEKRPNGHLPGTFKAEFINALYEITDEDVKEFKRVK"
     gene            20671..20757
                     /locus_tag="VW348_001070"
                     /pseudo
     CDS             20671..20757
                     /locus_tag="VW348_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(20907..21575)
                     /locus_tag="VW348_001071"
     CDS             complement(20907..21575)
                     /locus_tag="VW348_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEU9745982.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYNV"
     regulatory      complement(21790..21878)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(22132..23268)
                     /gene="lctO"
                     /locus_tag="VW348_001072"
     CDS             complement(22132..23268)
                     /gene="lctO"
                     /locus_tag="VW348_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEU9745983.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(23893..25383)
                     /gene="lysS"
                     /locus_tag="VW348_001073"
     CDS             complement(23893..25383)
                     /gene="lysS"
                     /locus_tag="VW348_001073"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEU9745984.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINKPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(25511..25657)
                     /locus_tag="VW348_001074"
     CDS             complement(25511..25657)
                     /locus_tag="VW348_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEU9745985.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            25690..26607
                     /locus_tag="VW348_001075"
     CDS             25690..26607
                     /locus_tag="VW348_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275026.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEU9745986.1"
                     /translation="MYIAVWGSLGSFLLGLIVSIIRHYRIPVLAQVATAYIELSRNTP
                     LLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSAMQDSGIQVLFQGNNLLRILQGL
                     GVTIGISILSVLLSMMFGTVMGIIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFG
                     LARNFNINISGETSVIIVFTLWGTAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYY
                     HIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTTSFW
                     IYGTILILYFAVCYPISKLSTHLEKHWRN"
     gene            26608..27366
                     /locus_tag="VW348_001076"
                     /pseudo
     CDS             26608..27366
                     /locus_tag="VW348_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            27378..28238
                     /locus_tag="VW348_001077"
     CDS             27378..28238
                     /locus_tag="VW348_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9745987.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHPTYGDAAK
                     ADDLVVEGGH"
     gene            complement(28318..28965)
                     /locus_tag="VW348_001078"
     CDS             complement(28318..28965)
                     /locus_tag="VW348_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9745988.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKPGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(28962..29660)
                     /locus_tag="VW348_001079"
     CDS             complement(28962..29660)
                     /locus_tag="VW348_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745989.1"
                     /translation="MGKLSSYMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLSLLCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(29670..30422)
                     /locus_tag="VW348_001080"
     CDS             complement(29670..30422)
                     /locus_tag="VW348_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745990.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(30422..31186)
                     /locus_tag="VW348_001081"
     CDS             complement(30422..31186)
                     /locus_tag="VW348_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9745991.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(31282..31687)
                     /locus_tag="VW348_001082"
                     /pseudo
     CDS             complement(31282..31687)
                     /locus_tag="VW348_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(31867..32499)
                     /locus_tag="VW348_001083"
     CDS             complement(31867..32499)
                     /locus_tag="VW348_001083"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEU9745992.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKDDQENWQEG"
     gene            complement(32533..33234)
                     /gene="pyrF"
                     /locus_tag="VW348_001084"
     CDS             complement(32533..33234)
                     /gene="pyrF"
                     /locus_tag="VW348_001084"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEU9745993.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            33555..33647
                     /locus_tag="VW348_001085"
                     /pseudo
     CDS             33555..33647
                     /locus_tag="VW348_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(33969..34682)
                     /locus_tag="VW348_001086"
     CDS             complement(33969..34682)
                     /locus_tag="VW348_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9745994.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNETLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(34675..35508)
                     /locus_tag="VW348_001087"
     CDS             complement(34675..35508)
                     /locus_tag="VW348_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9745995.1"
                     /translation="MIEVSHLSKSFGDKIALNDISFTVKEGQIFGFLGPSGSGKTTTI
                     NILTGQLLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMSLYNNLLFYSKFY
                     NISKLRVDNLLKRVGLYDSCKMVAGKLSTGMRQRMLLARALINKPAVLFLDEPTSGLD
                     PTTSRTIHELILELKTAGTTIFLTTHDMNEATLLCDYVALLNKGKLVEQGAPSELIQR
                     YNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLEDIFITLTGGKLN
                     A"
     gene            complement(35718..36866)
                     /locus_tag="VW348_001088"
     CDS             complement(35718..36866)
                     /locus_tag="VW348_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HEU9745996.1"
                     /translation="MDSRYSRTKGYYSLFYNEEYNKIQNKTVLVLGAGALGCYISLSL
                     SMYGVRKLIVADYDIIEPSNLNRQILYTESDVGKEKINVLSQKIHKYNSDVQVVPISI
                     KVSSVEELENIVAEYGSIDFIVKAIDTPIDIIKIVNQFAVSHKISYISGGFNGCYLII
                     DNIYIPTIGSCFACRNINKDINKYTLSDKTKWPTTPEMPAILGGIMTNLIIKIFLGCY
                     NEILIDNAYVYNMRNHALSQEKYVLENGECPICKKNNKVKDNNIRAKTFIRSVCFCLL
                     SGGVAFLSAIGQFTVIETQLIVLFLGIIFAIYYAYYNKNIQTSLENIVWLFSSFEILF
                     LLVNFRTFIQLPVDIFISMIIFLMLWIFIMLGIVCLSYYITLLFSKEA"
     gene            complement(36903..37091)
                     /locus_tag="VW348_001089"
                     /pseudo
     CDS             complement(36903..37091)
                     /locus_tag="VW348_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828969.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
     gene            complement(37075..37701)
                     /locus_tag="VW348_001090"
     CDS             complement(37075..37701)
                     /locus_tag="VW348_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
                     /protein_id="HEU9745997.1"
                     /translation="MYIYRADILTNFQNFPITLNILLFWLLVVIISATIHEFSHAIIA
                     NNYQIEIPNCGIMLLLFNLAFFVDLSGVQFLKNKKQFLKIMLAGIASNSILSLTGLLV
                     LLFTSYKLLGLLFFIINLGMIFINSIPFFQYDSGIILRYLNSNNNNLNFQYIVQLLIA
                     FVIIYFPLSQLLQFLTPNIIVRSIGGVVVSILLSILYMRGRTKYVLRK"
BASE COUNT        11655 a         7497 c         7248 g        11365 t
ORIGIN      
        1 agaaatagag agtgatttat tacaattcag taccacaaat taagaaagca atgcctattt
       61 tttgtactct caagatttaa gtaactgtac aactgcaatt aaatttatta atttactctc
      121 attgtgatat attcatacaa aaaccgctca gctgagcggt tttagtctat tctttccttt
      181 tacagtaccc atgttcggat ggcgtgggca acgccggatt cgtcatttgt tttagtgatg
      241 tatttggcga tttttttgat ttctggattt ccattttcca tgacaacggg gtttccaacg
      301 acttccagca tggcacggtc attttcttcg tcaccgattg ccatggtttc atctttggtc
      361 aatccgagtt tttcagccaa gtgagtaatg gctgaaccct tgtctacatt ctttgtaagg
      421 agttcgaggt agaaaggagc agatttgttg atggagtagc gctcgtaaaa ttctgctgga
      481 attttttcaa tcgtagcatc gaggatttct ggttcatcga tgaacataca tttgacaatt
      541 tccttgtcag ccatttcttc aggtgtacgg tagaagatag gcatgctgac gagggttgat
      601 tcgtgcacag tgtattttcc gatattgcga ttggcagtat agataccgtc cttggtaatg
      661 gcgtgcatgt ggacaccgag cttgcggctg agaaattcca tatctagata atcctcataa
      721 gtcaaggatt cgctgataat ctcatgtcct gtagcagttt cttggacaag ggcaccgttg
      781 aaggttacca catagtcccc ctcgtctctc aactgcaagt cgtctagaag tttggcaacg
      841 cctgcgatag ggcggccagt tgcaatcacg actttgacac cagcttcttt ggcatcttgg
      901 atggcagaaa agacttcagg agtgatttcc ttttggctgt tgactagggt tccgtcaata
      961 tcgacggcga ttagtttaat actcataaat ttcctctttt agtttttatt tggggtaaaa
     1021 tgatcgttct caatcaagtg taaaaattgc tgggtgatgc ttgcgaagat gctgttttgg
     1081 tctaacattt ctttcgggaa ataaaagcga ttatctccgt ggcgacttcc agcaagggat
     1141 tggacgatag gggacaggct agagagttct gccagttctc catttttttg taaaatctca
     1201 atctgtgtcc ttggattttc agattcggga cggtaaatat cataagggag gtcaaagttc
     1261 ttatgaatgg cagtatagta gtcgggatca aagccgatgt cctcaaccaa ttttctcatg
     1321 ctagcgagtt ggtcttggtc ttcttgtgaa aaggtaatgg atttaaagac cttgcggttg
     1381 acaaagcgat gcgataaatc tgcaagaatc ttgtcaggac tggtcatcca gagttggaag
     1441 taggtattca tcacaccatc atccagagcc agatagtcag tcaaggtcac atttttttcg
     1501 aagaaaggca ggaggtgtgg agaagttcgg gcaaagaaat ccttgtcctc aggatagagt
     1561 tccttggcgc gtttgagaag attctgtagg agaacttcca tggcgcgtgt tgcggggtgg
     1621 aaataaacct gcatgtacat ctggtagcga ctgaggacgt agtcttcgat ggcgtgcatg
     1681 ccattgcgct gaaaggcgat accattttcg ataggacgaa tgactcggag gattcgagtc
     1741 aggtcaaatt ccccatagga tgctcctgta aaataggagt cgcgcaagag atagtccatg
     1801 cgatctgcgt caatctgact agaaatgagc tgcacgacct gcttgttagg ataggtatgg
     1861 tctatgacac tggcaacttt ctctggaaaa tcgggcgcta cttgtagcag gacttggtga
     1921 atctctgtct caggattttg aataatctcc tgagtaatgg cttcatggtc tgtatcaaag
     1981 agattttcaa aagtatggga gtaggcacca tgcccaaggt cgtgtaggag agcagcggtc
     2041 atggtcaaga gagactcggc aggattccat tcctcaggat atttttcttc gaaaatctct
     2101 gtgatgcgtc gtgcaatttc atagactcct agacagtgag agaagcgact gtgttctcca
     2161 ccgtggaagg tataactgga agttcccagt tgtttgatcc ggcgcaaacg ctgaaattct
     2221 tttgtattaa tcaagtcata gatgatttga ttattgacat ggatgtagtt gtgaacaggg
     2281 tcacggaata ctttttcgtt catatgacca ttatagcaaa atcctgctct ttttggtaaa
     2341 atagtaggac aagagacaag aaagagggcc tgatgtgaag attcggatgc gaaatacaat
     2401 tcagtttgat gagcagttgg aagtgattga ccagctttat gatgtggaag tgcatgaaaa
     2461 aggagattat agctacctgc ttttctataa tgaggaaaag gaaaaagtag tgattaaatt
     2521 tcatggtcaa gaacttatga tgagccgatt ttccaatccc aagaccatta tgcgcttttt
     2581 aaaggatagt gatagtttgg cctatattcc tacccctatg ggcatgcagg aatttatcat
     2641 tcaaacgagc cgttatcaag tagatgggca aaagattgag ctagcttatc aactacaaaa
     2701 tcaagagggg catccctttg ccagctatca attggaaatt acttggggct aggatctcgt
     2761 ttttctcaaa tctactttct atcttcaagg attggctccc tagtgtggta gattaggcta
     2821 ttttttggta taataaaagt tatggaaatc gaaaaaacca atcgtatgaa tgcgctcttt
     2881 gaattttatg cggcgctttt gacagataag caaatgaatt atatcgagct ttactacgct
     2941 gatgattaca gtcttgctga gatagctgag gagtttggtg ttagtcgtca ggctgtctat
     3001 gacaatatca agcgaacaga aaagattctg gaagattatg agatgaaatt gcacatgtac
     3061 tcggactaca ttgtccgtag tcagattttt gaccaaatct tggagcgcta tcccaaggat
     3121 gattttctgc aggagcagat agaaatttta acaagcattg ataatagaga ataagaggaa
     3181 gaaaaatggc atttgaaagt ttaacagaac gtttgcagaa cgtctttaaa aatctacgta
     3241 aaaaaggaaa aatctctgaa tctgatgtcc aagaggcaac caaagaaatt cgcttggcct
     3301 tgctcgaggc cgacgttgcc ttgcctgttg taaaggactt tatcaagaaa gttcgtgagc
     3361 gtgcagtcgg gcatgaggtc attgatacac ttaatcctgc gcaacagatt attaaaatcg
     3421 ttgatgagga actgacagcc gttttaggtt ctgatacggc agaaattatc aagtcaccta
     3481 agattccaac catcatcatg atggttggtt tacaaggggc tggtaaaaca acctttgctg
     3541 gtaaattggc caacaaactc aagaaagaag aaaatgctcg tcctttgatg attgcggcgg
     3601 atatttatcg tccagctgcc attgaccagc ttaagacctt gggacaacag attgatgtgc
     3661 ctgtctttgc acttggaaca gaagtaccag ctgttgagat tgtacgtcaa ggtttggagc
     3721 aagcccaaac taatcataac gactatgtct tgattgatac tgcgggtcgt ttgcagattg
     3781 atgagctcct catgaatgag cttcgtgatg tgaaagcatt ggctcaacca aatgaaatct
     3841 tgcttgtcgt tgatgctatg attggtcagg aagcagccaa tgttgcgcgt gagtttaatg
     3901 ctcagttgga agtgactggg gtcatcctta ccaagattga tggcgatact cgtggtggtg
     3961 ctgctctgtc tgttcgtcac attactggaa aaccaatcaa gttcactggt acaggtgaaa
     4021 agattacgga cattgaaacc ttccacccag accgcatgtc tagccgtatc cttggtatgg
     4081 gggatatgct cactttgatt gagaaagctt ctcaggaata cgatgaacaa aaagcccttg
     4141 aaatggctga gaagatgcgc gaaaacacct ttgattttaa tgatttcatc gatcaattag
     4201 atcaggtgca aaatatgggg ccgatggaag acttgctcaa gatgattcca ggtatggcca
     4261 acaatccagc ccttcaaaac atgaaggtgg atgaacgcca gattgctcgt aaacgtgcca
     4321 ttgtgtcttc gatgacacct gaagagcgtg aaaacccaga tttgttaaat ccaagccgtc
     4381 gccgtcgtat tgctgctggt tctggaaata cattcgtcga agtcaataaa ttcatcaagg
     4441 actttaacca ggctaaacag ctcatgcagg gtgttatgtc tggggatatg aataaaatga
     4501 tgaagcaaat ggggattaat ccaaataacc ttcctaaaaa tatgccaaat atgggaggaa
     4561 tggatatgtc tgcccttgaa ggaatgatgg gacaaggcgg tatgcctgac ttatcagctc
     4621 tcggaggagc aggaatgcca gatatgagcc agatgtttgg tggcggtttg aaaggtaaaa
     4681 ttggtgaatt tgccatgaaa cagtccatga aacgtatggc taacaaaatg aagaaagcga
     4741 agaagaaacg caagtaagac aagagattga tgcaaatctc atttgatgag aaaataaagt
     4801 aaaaatttct atgataaaac gtacagtatc aaggttttag aatatctgat attatacgtt
     4861 ttttgatttt aataattttg ttaagacact tttattatag tatacgaaaa atccactcag
     4921 ctgtctgagt ggattaggtg tatttagact cttagtcttt attttcgtat ggcaagatca
     4981 agttcaagat gattcctgtc atggctgaaa gggcagtacc tgaaagtgta actggaccaa
     5041 gtttaaggat agctcctcca agtccaagaa ccaacatagc acttgcgatg atgaggtttc
     5101 gcatttgagc gaaatcaaca cgttctttaa tcaagacttt caaaccattg ctggcgataa
     5161 ccccatagag aaggattgac ataccaccaa gtacagcgtt tggaatagtt gaaatcaagg
     5221 cagtgaattt accaaggaag ctgagggcaa tcgcgatgaa ggcagcgtta cggataactg
     5281 agacagaagc gatacgagtc ataccgataa cccctgtatt ttctccgtaa gttgtattgg
     5341 ctggtccacc aaggaaggca gaaacagaag ttgcgatacc gtcaccaata agagtacggt
     5401 gaagacctgg ttcttttaag aattgacggc cacagatttg acccaaaaca gtatggtctc
     5461 cgatatgttc agaaattgtt acgatagcga ttggcaagat agcgatggct tctggaccaa
     5521 agtaaagatt gtactcttta aaggcaccac ttgtgctaaa tggcaagtag aaaccaggaa
     5581 tttcaaacca gttagcttct aggacaggcg taaagtcaac caaaccaaga gttagtgcga
     5641 agaggtaacc accgataatg gcaaagagga atggaatgat tcgtaggaag ccttttcctt
     5701 ttgtattgat aaaggcagca attaggaaag taacaacggc taccagagca tttttccaat
     5761 ttccgtctgc tacaagacct gcattggtaa cagctgaacc tgcaagtcca agaccgataa
     5821 cgatgatcat aggaccgata atgattggtg gcaagagttt atcaatccat tttgttccta
     5881 caaatcggat gctggtagca acaaggacat agaccaaacc agtcaagata acccctgttt
     5941 gagcagcaga tacatccccc cccatttctt tcatagccag tgacatagct gtgataaagg
     6001 cgaatgaaga acctagataa actggaactt taaaaccagt agcaagcatg tagatgagtg
     6061 ttccaacacc tgaagcaaaa agggcaacag atacaggcat tcccaaaatc aatggtacca
     6121 agatggtcgc accaaacatg gcgaaaacgt gttggaaact aaggagaatt ccttttccag
     6181 ccgaaggacg ttggtcaacg tctagtaaca aatcaacagt tgattcttgt ttcatataaa
     6241 cctcactttt gggcatcaaa aaagagccca ttattttaca gcaataggcc ctcagagtaa
     6301 gacttcttta aaatttagat tttaaagagt tttaaatatt tctgcgtctt cgtcacctca
     6361 cgggatgaca ttaaaaacct ttgcttagga tagtatagca gaaaaaaatg attttgtaaa
     6421 tcattttttc ccgagcctag aaataaaaga gcgaggctga ttttgtaaac atttgtttac
     6481 taaaaaattt aaagtgggcg tttatttggc ataccagcct tacgtggata tttatttggt
     6541 gtttcttttt tcttttctac cactgtgata tagcgcggat ctctattcgg tagggcgtag
     6601 ctgagattgt cttcgacctt actaaaaagg agattgaggg cattcttagc ttctaataat
     6661 tcctcaggcg cattgctggc cttgagtgcc aatagttttc caccaacctt aaggtaggga
     6721 atggtcaatt cagataggac ctgcatacgg gcaaccgcac gagctgttac aaaatcatat
     6781 tgagcacgga agttcttgtc ttgggcaaaa tcttcggcac gtccgtggta gaaatgaact
     6841 ccgttcaaat ccagttcttg agccaagagt tgtaggaagt tgatgcgctt attgagtgaa
     6901 tcaataatgg tcacatctaa ctccggatag agaattttca ttggtagact aggaaatcct
     6961 gccccagccc cgatatcaag aagtttgata gtttcattgg gaatcaaacc ttgaagaatg
     7021 ggtgcaatcg aatcgtaaaa atgtttgaga taaacttctt ccttgtccgt aatcgccgtc
     7081 aaattaatct tctcattcca ctcgaccaag agctcaaaat aacgttcaaa ttgttctttt
     7141 tgctggtccg aaagtggaag attctgctcg gcaagcaagt tgtaaaatgt ttttggtttc
     7201 atagttattt ccttctttag tatcatctta ttttaccaca atcatagaaa atttgatata
     7261 ctggtactaa tctaaaagca gaaaggactt atattatgac ttggattatt cttggagtta
     7321 tcgctcttat tgttattttt gtgattgtta gctataacgg tttggttaaa aatcgtatgc
     7381 aaaccaagga ggcttggagt cagattgatg ttcagttgaa acgtcgaaat gacctcttgc
     7441 cgaacttgat tgagactgta aaaggttatg ccaaatatga aggttctacc cttgaaaagg
     7501 tggcagaact acgtaaccaa gtggcggcag cgacttcacc agcagaagct atgaaagcca
     7561 gtgatgccct cactcgtcag gtttcaggta tttttgcagt tgcagaaagc tatccagatt
     7621 tgaaagctag tgctaacttt gttaaattgc aagaggagtt gacaaacaca gaaaataaaa
     7681 tttcttactc tcgtcaactc tataacagtg ttgtcagcaa ctacaatgta aaattagaaa
     7741 ctttcccgag caatattatc gctggaatgt ttggatttaa agcggcagat ttccttcaaa
     7801 cacctgaaga ggaaaagtcg gttcctaaag ttgattttag cggtttaggt gactaagatg
     7861 ttgtttgatc aaattgcaag caataaacga aaaacctgga ttttgttgct ggtatttttc
     7921 ctactcttag ctcttgttgg ttatgcggtt ggttatctct ttataagatc tggacttggt
     7981 ggtttggtta tcgcactgat tatcggcttt atctacgctt tgtctatgat ttttcaatcg
     8041 acagagattg tcatgtccat gaatggagcg cgtgaggtgg atgagcaaac ggcaccagac
     8101 ctctaccatg tagtggaaga tatggctctg gtcgcccaga ttcctatgcc ccgtgttttc
     8161 atcattgatg atccagcctt aaatgccttt gcgacaggtt ctaatcctca aaatgcggct
     8221 gttgctgcga cttcaggtct actagctatc atgaatcgtg aagaactaga agctgttatg
     8281 ggacatgaag tcagtcatat tcgtaattat gatatccgta tttcgactat tgcagttgcc
     8341 cttgctagtg ctatcaccat gctttctagt atggcaggtc gtatgatgtg gtggggtgga
     8401 gcaggtcgca gacgaagtga tgatgaccga gatggaaatg gtcttgaaat cattatgcta
     8461 gtggtttccc tactagctat tgtactggca cctctcgctg caaccttggt tcagctcgct
     8521 atttctcgtc agagggaatt tctggcagat gcatctagtg tcgagctgac tcgcaatccc
     8581 cagggaatga ttaatgccct agataagttg gacaatagca aacctatgag tcgccacgtc
     8641 gatgatgcta gcagtgctct ttatatcaat gatcccaaga aaggtggggg gttccaaaaa
     8701 ctcttttata cccacccacc tatctcagaa cggattgaac gtttaaaaca gatgtaaaat
     8761 gaaggctgga aaaaagtctt taaaatctga aaaacgcata atatcaggtg tgaaaacttg
     8821 atattatgcg ttttactatg ggaagattta cttctttttc tcctaaaatt gtgtttttgc
     8881 cccacctatc tgctatgttg caaatttata aatcttctaa attaactagc ttcaaaccgt
     8941 gttctgtcat gcgatagatg atcgagcaga tttcttttaa gaaacgacgg tcatgcgaaa
     9001 cagtgatgag accgcctgga taggttgcaa agagttttct gatttggggt tgagaagtgg
     9061 gagaaaagtt tcgtgtgggt tcatccagca ggagaaagtt tggtttgcgc aggactaaat
     9121 ccaaaagcag gagttttccc tgttgtccgc cagataagga gcgaatttga tgctgcattt
     9181 ctggataact gaaattgaga ctggctaggt gagattggat tttctgaagt tcctcttttt
     9241 ccccagtttt gcttatataa gctattggtg ataaatccaa ttgcagtttt ttgtggtaat
     9301 cttgtggcat aaaaccaagg gaaatctctc ttttatcatt cagaagttgc tttaatttgg
     9361 ctaacagagt tgatttccca acaccatttg gcccgataat accgattttt tcttgcccac
     9421 ggacagttag ttgtagtttt tgaaccaaaa ctcggtcgtc aatggacaaa ttttcttttt
     9481 ccagttggac taagacttta gaagctggta atggttggat gtctgaaaag aaaagttgga
     9541 tttgttcctc ttcaagtggc ttttgagtca tggactgagc tgtcttttcg tagcgttttt
     9601 cttgtgagag gacagttttc atctttttag ccaataggcg accggcagta ctatctttgg
     9661 tagctcgaag cgcagtttct acattttgct taactctccg atgtttttcc atggttttat
     9721 cgtaggctct ttggttgtta gcagcttgct gactttgttt ggcaaaatta gcctttctct
     9781 gctcactata gctatcatag tctaaatgct ctactagcgt ttccgcttct ttacggtgtt
     9841 tgaccagtcg caagtgaaca atagtgtctg ctgtttcaga aagaaagtct tcatcatggg
     9901 aaatgaaaat aacggtttgc ctggtctttt gaatctggcc ttttagccaa tcaactgtct
     9961 caaggtctag gtcatttgaa ggttcatcta aaaatagaat ctcaaagggt ttggctaact
    10021 catggataag ctgaattttc aaagcttctc cccctgatag attgccaatc ttttggtcac
    10081 ttgcgaaacg attgctatca aaatgcaatt cctccgccaa acgatagagg atactgtagt
    10141 ctaaatcaat agaatctaaa aagaagtagt cgtgtaaagt tttctttttc agctcctcgg
    10201 gaagtttttg aggaatgtag gccagtgact gatagtcaga ttggatgttt cccttgatag
    10261 tgaaatcaga caaagcttcc cccattaaaa ttttaagtaa ggttgatttg ccatttcctt
    10321 cttcaccaat aatagcaacc ttttccccgt cttggatggt catgcttagg tcagatacaa
    10381 gatctcgtaa atctttgttt tgtgtgatgg ttagatgatt gatttttatc atatgatttc
    10441 cctttctaga atgttcatag tgcataacaa aaagctctac tttacctagt agagcccaaa
    10501 gtctatgtca aaaaaactct attaacatgc cagaaaaaga gcataaaaga gcacacaaaa
    10561 agagacaaaa acaagatcta ctaaataaag gttctttatt tgatagactt agttgttcat
    10621 gtctccctta cctccgagta ttagtatctt tatattatac ctttaaggaa attttgtcaa
    10681 cagaaaactg gaaattctat gctctaaaat ccaaaaacag gtccatagag acttagtacg
    10741 tgtttgacat gctcgtaatg gaatttatca tagtttcgcc aagcagtgcg tgcttgatcg
    10801 tttagtttta ggctacccag tccaatcaga agactggtgg gttggtaaaa tttctcaaga
    10861 tcaattaaga tactgttgtt caacttttcc gtttttttga gctcttgcat agtagtgttt
    10921 agcagctctt gtagtcgaat atcatctgcc gtaccctgtt tacagttttg gtagctttta
    10981 tttaacttgg ataggagttg aatgagtttc ttgtcttcca tgtgagcatc ctccttgatc
    11041 tgatgtactc tttccctata gtatagcact aaaaaacaaa actgtcatag taaatatgtt
    11101 aaaattctga attttaatta caaagtttgg tgtgctgatt tgtagccttt tcatggtata
    11161 atcaagagag taaatcttta tggaggaagt atgaaattaa atattcaaga aattcgtaag
    11221 cagtctgaag gtttgaactt tgaacaaacg ttagatttag ttgatgacct gcgtgcacgt
    11281 aatcaagaaa ttttagatgt aaaagatatc cttgcagttg ggaaagtaca atatgaagac
    11341 cgtatgtatt tcttagatta tcaactatct tataccattg ttcttgcttc gagtcgcagt
    11401 atggagccag ttgagttagt tgaatcttat ccagtcacgg aagttttcat ggaaggcgca
    11461 actaaccatc taaatcaaga aattttagat gatgacttgg tcttgcccat cgaaaatgag
    11521 gcgcttgacc ttgctgagag tgtatcagac aatatcttgc taaacattcc tatcaaggtc
    11581 ttgacggctg aagaagaagc tggtcaagga tttgtctcag gaaatgactg gcaaatcatg
    11641 acagaggaag aataccaagc tcaacaagca gtaaagaaag aagaaaacag tccttttgct
    11701 ggcttacaag gactatttga cggagatgaa taatggtctt gtcaaaaaaa cgagcacgaa
    11761 aggtgctaga agaaatcatt gccctcttcc cagatgccaa gcctagtctt gattttacca
    11821 atcattttga actcctggtt gcggtcatgt tatcagccca gacgacagat gcagcggtaa
    11881 ataaggccac accaggtctc tttgttgcct ttccaacacc ccaagctatg tctgtagcga
    11941 cagagagtga gattgcttca catatttctc gcttgggatt gtatcggaat aaagctaaat
    12001 tccttaaaaa atgtgcccaa cagttactag acgattttga tggtcaagtc cctcagacac
    12061 gtgaagaatt ggagagtttg gcaggtgttg gtcgcaagac agccaatgtt gtcatgagtg
    12121 taggatttgg gattccagcc tttgcagttg atactcatgt ggagcgtatt tgcaaacacc
    12181 acgatattgt caaaaaatca gcgacgccac ttgaggtgga aaagcgggtc atggatatct
    12241 tgccgcctga gcagtggtta gctgcccatc aggccatgat ttattttgga agagccattt
    12301 gccatccaaa aaatccagag tgtgaccagt acccacaatt atatgatttt agcaatttgt
    12361 aagatgctac attgaaactt tttgcttgat tttaagcatg ctttgtgcta tagtaaatga
    12421 taactaaata ttcctttaaa cctgtcccgt gaggcaggca aggagcgcga taaagtagaa
    12481 gggtgaagtc tatactgtgt gcagtagggc tcgcttggct ataaatttca agtctccttg
    12541 tttaaggaga cttttctttt tggaggtttg tcatgaaaac aaaagaagtt gtagacgaat
    12601 tgaccgtcaa acgagcgatt acgcgtatta cttatgagat tatcgaacgc aacaaagatt
    12661 tgaataagat cgtcttggct ggtattaaaa ctcgtggtgt ctttattgcc caccgaatcc
    12721 aagaacgttt gaagcagtta gaaaatcttt cagttcctgt tgtggaattg gatactaaac
    12781 ctttccgtga tgatgttaaa agtggagaag atacttcttt ggtttctgtc gatgtgacag
    12841 accgcgaagt tatcttggtg gatgatgtgc tctatacagg tcgtaccatc cgtgctgcta
    12901 ttgataatat tgtcggtcat ggtcgtcctg cgcgtgtgag tttagcagtt ctagtcgatc
    12961 gtggacatag agaattgcca atccgtccag attacgttgg aaaaaatatc ccaaccagtc
    13021 gttctgaaga aatcatcgta gagatgacag aacttgatga ccaagacaga gttctgatta
    13081 ctgaagaagc ttagaaagtt aaaggagtag ccatgtcaga aaatcaacaa gcattgaacc
    13141 atgtggtgtc catggaagac ctcactgtcg atcaagtaat gaaattgatc aagcgaggaa
    13201 ttgagtttaa aaatggagcc cagcttccct atgaagacca tccgattgtt tccaatctct
    13261 tctttgagga ttctacacgg acacataagt cctttgaagt cgcagagatt aaacttggat
    13321 tggaacgact tgactttgat gtgaagacta gttcggttaa taagggtgag acactttatg
    13381 acaccatttt gactctgtct gctttaggag tggatgtctg tgtgattcgc catccagagg
    13441 tcgactacta tagagaattg attgctagtc caacgattac gacttccatc atcaatggtg
    13501 gagatggttc gggccaacac cctagccaga gcttgcttga tttgatgacc atttatgagg
    13561 aatttggcca ctttgagggt cttaaagttg ctattgcagg tgacttggac cactcacgcg
    13621 ttgccaaatc caatatgcag attttgaaac gcttgggatc tgaactcttt ttcgctggac
    13681 ctgaggaatg gagaagtcaa gagtttgcag actatggaca gtttgtaacc attgatgaaa
    13741 tcattgatca ggttgatgtc atgatgtttc tccgtgtgca acacgaacgc catgatagtg
    13801 gagctgtatt ttcaaaagaa gactaccatg cccaacatgg cttgactcaa gaacgttacg
    13861 atcgtttgaa agaaacagca atcctcatgc acccagctcc aatcaatcgt gatgtagaaa
    13921 tagcagacca cttggttgaa gcaccaaaat cacggattgt ccaacaaatg accaatggtg
    13981 tctttgttcg aatggcaatc ttagaatccg tactagcgag tagaaacgcc aactaaaaca
    14041 caagacgtta aaagacgcca gtgagcgtcc acgagaggtg aaaatatgac aaaaagaatt
    14101 ctagtattag aagatggcac agtttttgaa ggcaaggcct tcggagcaga tattgatgta
    14161 acaggcgaaa tcgtctttaa tacagggatg accggctacc aagaatccat tacagaccag
    14221 tcttataatg gacaaatctt gacctttact tatcctttgg taggaaatta tggtattaat
    14281 cgtgatgatt atgaatccat tattccaact tgtaagggag tcgttgtttt tgaagaagcg
    14341 cgtagagcta gcaactggcg caaccaaatg accttggatg aatttttgaa agccaagaaa
    14401 attccaggga tttcaggaat tgatacgcgt gctcttacca agattatccg taagcatggt
    14461 actatgcgtg caaccttgac ccatgttggg gacagtatgg accatgtgac ggaccagctc
    14521 caagcaacag ttttaccgac agacaatatc aaacaggttt ctactaaaac gtcttatcca
    14581 gctccaggag ttggtttgag cgtggtgcta gtggactttg gtctcaagca ctcaatccta
    14641 cgtgaacttt ctaaacgcaa ctgtaacgtg acagttgttc cttattcgac aacggctgaa
    14701 gaaattctcc atctcaatcc tgacggagtt atgttgtcaa atggtccagg taacccagaa
    14761 gacgttccac aagcactcga catgattcgc ggtgtacaag gaaaaattcc aatctttggt
    14821 atttgtatgg gacaccaact ctttgcaatg gcaaacgggg ctaagaccta taagatgaag
    14881 tttggccacc gtggattcaa ccatgcggta cgtgaaatcg caacaggacg agtagacttc
    14941 accagccaga accatggtta tgcagtcagc cgcgaggatt tgccagagca cttgattatt
    15001 acccacgaag aaatcaatga caagtcagtg gaaggtgtgc gccacagata ccaacctgct
    15061 ttctctgttc aataccaccc agatgcagct cctgggccac acgacgctag ctacctattt
    15121 gacgagttta tcgagatgat ggaagttttt aaacaatcaa actaagaacg agtaaaagct
    15181 cgtcggagaa tttatgtaac tgaacacgga cggaaagctc agaatgtaga gaaaccaact
    15241 tggattgtca atccttcctt gatttcctaa aattcaatcg ctttctattc gtcctttgta
    15301 tcttatttaa tgtcgccctg agaggcgacg aatagaaagg agaagggagc tccgtatttg
    15361 ctgaactgaa tacgggctac ggacggtgct aaaaagatag ttattcctag aactgacagt
    15421 tcttcgtcat aactcctatt ttagctttgt ccgcttgaca cccttaatat cttatatatg
    15481 cctaaacgta ctgatattca aaaaattatg gtgattggtt ctggtccgat tattattggt
    15541 caggctgctg agtttgacta cgctgggact caggcttgct tgtcgttgaa agaggaaggt
    15601 tatgaggttg ttttggttaa ctcaaatcct gcaaccatca tgacggacaa ggaaattgct
    15661 gacaaggttt acattgaacc gattacactt gagtttgtga cacgtattct tcgtaaggaa
    15721 ggtccagatg ccttgctacc aacactcggt ggtcagacag gtctcaacat ggccatggaa
    15781 ttatctaaaa atggtatcct agacgagctt ggcgttgaac ttctgggtac caaattatct
    15841 gccattgacc aagcggagga ccgtgatctc tttaaacaat tgatggaaga gcttgaacaa
    15901 cccattccag aatctgaaat tgttaacaca gtagaagaag cagttgcctt tgcagcgaca
    15961 attggctacc cagtcatcgt tcgtccagcc tttacccttg gtggtactgg tggtggtatg
    16021 tgtgccaacg agaaagaatt gcgtgaaatc actgaaaatg gtttgaaatt gtcacctgtt
    16081 acccaatgtt tgattgagcg ttcgattgcc ggtttcaagg aaattgaata cgaagtgatg
    16141 cgtgactcag ctgacaatgc cttggttgtt tgtaacatgg aaaactttga cccagttggg
    16201 attcacacag gggattccat tgtatttgcc cctgcgcaaa ccatgtcaga ctatgaaaac
    16261 caaatgcttc gtgatgcgag cttgagcatt attcgtgccc tcaagattga aggtggatgt
    16321 aatgttcagc tagctcttga tcctaacagc ttcaagtatt atgttatcga agtaaaccct
    16381 cgtgtatcac gttcgtcagc ccttgcttct aaagcgacag gatatccgat tgctaagttg
    16441 gctgccaaga ttgcagtagg tttgaccttg gatgaggtta taaacccagt tacaggttca
    16501 acctatgcca tgtttgaacc agcccttgac tacgtagttg ctaagattcc acgtttccca
    16561 tttgacaagt ttgaaaaggg tgaacgccgt ctcggtacac aaatgaaggc gactggagaa
    16621 gtcatggcaa tcggtcgtaa catcgaggaa tctcttctca aggcctgccg ctcccttgaa
    16681 attggggtgc accacaatga aatacctgaa cttgcagcag tttctgatga taccttgatt
    16741 gaaaaggttg tcaaagccca agatgaccgt ctcttctacg tatcagaagc cattcgtcgt
    16801 ggctacacac ctgaagaaat tgcagagctt acaaaaattg atatcttcta tcttgataaa
    16861 ctcttgcata tctttgaaat tgagcaagaa ttgggtgctc atccacaaga tctagaagtt
    16921 ttgaaaacag ccaaacttaa tggtttttca gaccgtaaga ttgctgaact ctggggaacg
    16981 actgatgata aagttcgcca acttcgcttg gaaaacaaga ttgttccagt ttataagatg
    17041 gtagacactt gtgcggcaga gttcgattcc gaaacgccat atttctattc aacctatggt
    17101 tgggaaaatg aatctatcaa atctgataaa gaatctgtac ttgtcctagg ttcaggtcca
    17161 atccgtatcg gtcaaggggt tgagtttgac tacgcaaccg ttcactctgt taaggctatc
    17221 caggcagctg gttatgaagc tatcatcatg aactcaaacc cagagaccgt ttcaacagac
    17281 ttctctgtat cagataagct ttactttgag ccattgacat tcgaagatgt tatgaacgtc
    17341 attgacttgg aacaaccaaa gggagttatc gttcagttcg gtggtcaaac agccatcaac
    17401 cttgcagagc cattggcaaa agcaggtgtg accatccttg gtacacaggt tgctgaccta
    17461 gaccgtgccg aagaccgtga cctcttcgag caagctctca aagaattgga tattccacag
    17521 ccaccaggac aaacggctac caatgaagaa gaagcagctc ttgcagctcg taagattggc
    17581 ttcccagttc ttgtccgccc atcttatgta cttggtggac gtgccatgga aatcgttgaa
    17641 aacgaagaag accttcgttc ttacatgcga actgctgtta aggctagtcc agaccatcca
    17701 gttcttgtcg actcttatat cgttgggcaa gagtgcgaag ttgatgccat ttcagatggt
    17761 aaaaatgtac tcattcctgg tatcatggag catatcgaac gtgctggtgt ccactcaggt
    17821 gactcaatgg ctgtttaccc accacaaacc ttgtcgcaaa aggttcagga gaccatcgca
    17881 gactacacca aacgcttagc aatcggtctt cactgccttg gaatgatgaa catccagttt
    17941 gttatcaagg atgaaaaagt ctacgttatt gaggtcaatc cacgtgccag ccgtaccgtt
    18001 ccattcctat ctaaggtaac caatattcct atggctcaag tagcgaccaa gctcattctt
    18061 ggtcaaagtt tatcagaact tggctaccaa aatggacttt accctgaaag cacccgtgtt
    18121 catatcaagg cacctgtctt ctcctttacc aaactagcta aggtagacag cttgctcggt
    18181 cctgaaatga agtcaacagg tgaagttatg ggttctgatg ctactttgga aaaagctctc
    18241 tataaagcct ttgaagcttc ttatctacac ttgccaactt ttggtaatgt cgtctttacc
    18301 atcgctgatg atgccaaaga agaagccttg aacttggctc gtcgtttcca aaacattggt
    18361 tatggaatcc ttgcgacaga agggacagca gccttctttg ctagtcatgg cttgcaagcc
    18421 caacctgttg gtaagattgg tgatgacgat aaggatatcc caagttttgt acgcaaagga
    18481 agaattcaag ctatcattaa cacagtagga acaaaacgaa ctgctgacga agatggtgag
    18541 caaattcgtc gttcagccat tgaacacggg gtgcccctct tcacagcgct agatacagct
    18601 aatgccatgc ttaaggtact tgaaagtcgt agctttgtta cagaagcgat ttaaatagaa
    18661 aaataagata tagcagactg aatttagaac agtacacagg gatactaaaa tatttctaga
    18721 aattaatttg aattttctaa ttgatttgtt cgcatcttat ttcaatctac tatatcatct
    18781 tcatccagtt tcgtaaaaga aaaaactcta attacagata cgaattagag ttcagcttac
    18841 aagattagac agttcttttc gacatacgaa aaaaacattt cacatttccc ttcgccagtc
    18901 ttaactgtat caggttcaat gggtatcatc tcagcctaaa gcaccccaaa tgcctttatt
    18961 atttaattat gtgattatta taacacacat tttatactag ttcaagaaat tgaactggaa
    19021 atacagcctt gcactcacaa agacagcaga tctttctttt gcaaaaaaca aatgacctgt
    19081 ttgatgaatt agccattcaa gctgaatcta gacatagctt tttaaaaaag gaaaatccta
    19141 cttacttaga atccaaggat agatatctat tgttcactca tttcccgaac agttttttct
    19201 atattttttg catacgatat tgccgaaatg attgaaacgc cgtcaacatt ggtctttata
    19261 atgtctttaa tatgtttcgt ctgtatccca ccaattgcaa ctaaaggcat ttgtggcaat
    19321 agttttctca tcaattcaag accttcataa cctatagcac caccagcatc atcttttgac
    19381 tgggtatcaa atacaggccc aacacctaca taatctacat attcaacttt tgattgttga
    19441 aattcttctt cgtttcttat agaaagacca attattttat ctggcatcaa ttttctaatt
    19501 tcatcaacac caatatcatc ttgacctaca tgtacgccat cggcgtcaat ttccattgct
    19561 aaatctatat cgtcattaac gataaatgga acattgtatt ttttacaaag ttctttaatt
    19621 tggatagcta gctcaagttt ttctaagcct tctaaagcac cctcaccttt ttctcgaaat
    19681 tgaaataagg ttatagcacc ttttaaggct tcctcaacga ctgtatatag attttttcct
    19741 tggcaagtag tcgttccaca aataaaatat agttttagta attctttatg aaacatctta
    19801 cttcactctt ttgaattcct ttacatcttc atctgtaatc tcgtataagg catttataaa
    19861 ttcagcttta aatgttccag gaagatgtcc attgggacgt ttttctgcta tttctccagc
    19921 gatattgtaa accaacattg ctgtttctaa tgatttcaat tcttgacctt tttctagtcc
    19981 gataaagctt gctactacag ctcctaataa gcatcctgtc ccaatgactt tcggcatcat
    20041 agcactacca ttatgaatcg ttaccacttc tccattaaca gcaatggcat ccacttcacc
    20101 tgttactact attggaatat tgaacttctc atttgctgct agagcaattt cgtcaatatt
    20161 atctacgccc gcactatcta ctcctttaga tgccacatct attcctacta aagaggcaat
    20221 ctcgccagca tttcctctaa tcgctgctag tttataattg ttgattagat catccgctac
    20281 tttttttcta tattctcctg ctccacaggc tacaggatct aaaactgctg ggacattata
    20341 tttctccgca attttcagag cagcttggta taatttccaa ttttcatctg tcaatgttcc
    20401 tatgtttatt aataaaccac cagcatactt taacaaatcc tctaaatctg ctggaaactc
    20461 actcatggct ggtgaggcgc ccagtgctac taatccattt gctgtgaaat tttttactac
    20521 atcattggtt atacaaatga ccaatggtgc tttttctttt aataatttta aacttgtcat
    20581 attgaaatcc ttccttttca ctttatacga tctactgatt tcgatttata tctatctttc
    20641 gttaagaaat ttttttcatt tacattgaat gatttatact caatgaaaat caaagagcaa
    20701 actaggaagc taaccgcagg ttgctcaaaa cactgctttg aacctgtaga taagactgac
    20761 gaagtcagct caaaacactg ttttgaggtt gtggatagaa ctgacgaagt cagtaaccat
    20821 acctacggca aggtgaaact gacgttgttt gaagagattt tcgaagagtc ttacctcatc
    20881 aaatttgtaa atatcatgag ccttctctag acattgtaac caatatcaaa aaaagctaat
    20941 tctaaagcga ctgcttgatt ccagcgttgc tgaagttctg tcaaatcttc tcgattttta
    21001 ccgacacgat tgagttcgtc aaccagaaat tgaacccact ctgcaaagaa aggacctctg
    21061 tggagattga tccattccga atgaatatag acttcaggta gagccaaatc tttagaaccc
    21121 cagtctaaat agagaccttc tgcaatgacc agcataacca aaagatgggc atagtctgat
    21181 gaagccactg ccgaatacat tagatcctga aaggcttttg ttacagggtg caaagtcact
    21241 tctagatagt cattctctgc tacttttaac tctttaaaag ccttttggaa ataaccatct
    21301 tcatctgctt caagaaagcc tagttgcttg gcaaaacgaa gcttggattc aagtttatct
    21361 gcgtgagcta cgcaggcacc cagcatggat aagaaggcat caaagaagtg ataatcttga
    21421 atcagatagt cctttaagac cttattctca attgtccccg caaaaagttc cttaacaaaa
    21481 cgatgattga ttgcagcctg ccaatccttc tgactgcttt ttaataattc tccaacagtc
    21541 aaacctggct gaaatgcata gtcttgtgtt tccatattta cttctcctct ctttacttgt
    21601 tagtaattaa taaaacacca agaaatatca agcaaaatcg taattccact tgatcctttt
    21661 aaagcacatc gagagcattt gcagagagct aactaaacaa gcctatccag tttatataaa
    21721 caaaaaactc caattacaat caagaattag agttgactta caagattaga ccgttcattt
    21781 caccatacga aaaaactgtt cacatttccc ttcgccagtc ttaactgtat caggttcaat
    21841 gggtattatc tcagcctaaa gcaccccaaa tgtctctatt atttaattac tgaaccagta
    21901 tagcaaaaaa tgaaagccct agcaagatat ttgaccgaaa aatatcttta tatataatat
    21961 attgaaacta gaatagtaca cctctacttc taaaacattg ttagaaatcg atttaactgt
    22021 cctgattaat ttgtcctatt cttatttcat tttattatag ttttcgatag cgatttattc
    22081 ttccaataca cgaagaaaaa cctccacatt cagtggaggc aatctgtttt atcaatacaa
    22141 ttttaagtca cgagggtcaa ctgggaaggt tgggttgtat ggattgtgac ggagcttaaa
    22201 gtgtttgaca tcttcaatgg tctgagctcc agacaattgc ataactgtct tcaattccgc
    22261 attcaagtgt tcaaagactt gacgcacacc gacactacca ccgagagcca agccataaat
    22321 aacagggcga ccaatagcta ccaagtctgc tcctgaagcc aaggctttaa agacgtgttg
    22381 accacgacga acaccagagt caaagacaat cggcacacgt ctatcaactg cttctgccac
    22441 ttcttgaagc gagtcaaagg cagctggtcc accgtcgatt tgacgaccac cgtggttggt
    22501 tacccagata ccagaagctc ctgcagcaag tgaacgttca acgtcctcac ggcattgtgg
    22561 tcccttgaca tacacaggaa gaccagagta ttcagcgata aattctacat cgcgtggaga
    22621 caagcgttgt ttagctgatt tgtaaacaaa gtccattgat ttaccagcac cttctggcag
    22681 gtattcttca acaatcggca tgccaactgg gaagacaaaa ccattacgct tatccacttc
    22741 acgattcccc cctacagtag catctgccgt caagacaatc gctttataac cttcagcctt
    22801 cacacggtcc atgatgtggc ggttgatacc gtcatcctta ctaaagtaaa attgaaacca
    22861 atgaggtgtc ccttgaaggg cttcagaaat ctctggaagg tcaacagtag agtaagaact
    22921 ggttgtataa agagaaccaa actcatgcac accacgcgca gtcgccactt ccccctgttc
    22981 attcgctaat ttatgggccg caacaggcgc cataatgatt ggtgaagata gtttttcacc
    23041 tgcaaattca atctctgtac ttggattttc aacatcgcaa agtgtatgag gaacgatgag
    23101 tttgtggtta aaggcgcgga tattctctct taaagtgaaa gtatcttccg ccccactagc
    23161 gatatagcca aatgctgctt taggaataac ttgttgcgcc attggctcca aatcataggt
    23221 attgatgaag tctacatgac cttctgcatt gcttgttttg tatgacataa aatgccctcc
    23281 ttgattaagt aagcgtttgc tttttactac acaactataa taactctttt ttcaatcatt
    23341 ttcaagagtt ttgcttaaaa accatcttat tttttcatac aatatactag ccctactttc
    23401 cttaaactct aaactttagt ctatattaag tgaatcgttg agattttttg ctgccaggca
    23461 tttgaactac ttttttattt gcggattcta tctactaata ctataaaaaa acaagtgaat
    23521 aagacaccag aacatcctct aataggacct atggacttat atcagtccca tatatactgt
    23581 ttaagcaaga tactatccta gttgacgcta acttcctatc ccacttatta attttttatt
    23641 tatagtgaat ctgaacaaat caattgggaa atccaagtca atttctagta ctttttgaac
    23701 agtttcagcg tactatcgta aaatgaaata aaacatgcac aaattgatta gggaatttaa
    23761 accaatttct aacagtgtct tagaaatcaa agtgtactat ttcaacttca atatactaca
    23821 cttcattttc tccttaaatt cagtctcttt ttgaatcaaa aaatcccctg gtaagagcca
    23881 gagggtaaga atttatttca ttgttgggaa gagcaataca tcacggatag ttgttgtatc
    23941 agtgaggagc atgcagagac ggtcgatacc gattcccaaa ccacctgttg gtggcatacc
    24001 gtattcaaga gcctcgatgt agtcatagtc gatgcctgtc gcttcatcat caccaagttc
    24061 tttagcttta gcttgggctt caaaacggct aagttgatcg attgggtcgt tcaactcagt
    24121 aaaggcatta ccgtactcct tagtcatgat aaagagctcg aaacggtcag taaagcgttg
    24181 gtcttcagga tttttcttag cgagtggaga tacagctact ggatgtccat agacaaaggt
    24241 tggttggatt aaagtttctt cgacaaactc ttcaaagaag gcattgatga tgtgaccaac
    24301 ctcagtgtag tgtttctcaa ctggaacttt cttctcagca gcgatagctt tagcttcttc
    24361 caaagtcatg tcttgccaga aatcgacacc agtaatttct ctgatagcat ccaccatatg
    24421 aacacgctta aatggtttgt taatcttgat ttcagtacct tggtagttga ctgggccatc
    24481 acctttgact gatttagcag cgtgttggat aatgccttcc gtcaagtcca tgatgtcttg
    24541 gaaatctgca taagcttggt aaacttcgat agaagtaaac tcagggttat gagtagcgtc
    24601 cattccttcg ttacggaaga tacggccaat ttcatagaca cgttccatac cacccacgat
    24661 aaggcgtttt aagtgaagct cagtcgcgat acgaagcacc atgtcaatgt tttgggcatt
    24721 gtggtgggtg ataaatggac gggcagcagc accaccggct tcattatgaa gaacaggtgt
    24781 ttccacttca aggaatcctt tttggtcaag gtaacgacgg atttcagaga tgatttttga
    24841 acgagtgaca aagcgttcaa agctttcacg attagaaatc aagtcaaggt aacgtttacg
    24901 gtaaattgtt tcaacgtctg tcaaaccatg gaatttctca ggaagaggac gaagagcctt
    24961 agacaagtgt gtgatgtggg ttgccttgat agagagttct cccatatccg tacgcatcac
    25021 ttcaccttcg acaccaagga agtcaccaag gtctgctttt ttgaagattt cgtagttttc
    25081 ttcaccgaca gcatccttac gaacatagat ctgaatctgg ccttcgcggt cttgaaggtg
    25141 ggcaaaacca acttttcctt taccacgttt ggttaccaag cgtcctgcga tagtagctgt
    25201 ttcgttttta tcgtgtaatt gttctttatc gaggttggca tatttatctt ttaattcttg
    25261 tgaatttgca gtacgttcaa aacgttttcc gaaaggatcg attccttgtt cgcggagcgc
    25321 agccattttt tcacggcgaa cgatctgctg gtcatttagt tcttccatat gttctgtaga
    25381 catgggatcc tcctagtttt actcaaaatt gaatacgatg agtcattttt tgcgataccc
    25441 ccattttatc ataaataagc aagaaattca cggataatct ttaaaaacta aaaagaacct
    25501 gacgctaaaa tcactggaaa gaagtgaaag tatcttccgc cccactagcg atatagccaa
    25561 atgctgcttt aggaataact tgttgcgcca ttggctccaa atcataggta ttgatgaaat
    25621 ctacatgacc ttctgcattg cttgttttgt atgacataaa atgccctcct tgataagtaa
    25681 gcgtttactt tgtatattgc agtttgggga agtttgggat cctttctgct cggtttaatc
    25741 gttagtatca tccgacatta tcgaatccct gttttggcgc aagtagcgac agcctacatt
    25801 gaattgtcac gtaatacgcc ccttttgatt caactcttct ttctctactt cggtcttccc
    25861 cgaatcggga ttgtcctatc ttcagaagtc tgtgcaacgc ttgggcttgt ctttttagga
    25921 ggctccgcca tgcaggattc gggaatccaa gtactctttc aaggaaataa cctcctgaga
    25981 atcttacagg gattgggcgt tacgattggg atatccatcc tgtctgtcct cttatccatg
    26041 atgttcggaa cagtcatggg aatcatcatg acctcccatt ctagaatcat acgattttta
    26101 acacgattgt atctggaatt tatccgtatc atgccccagc tggtgctact cttcatcgtt
    26161 tactttggct tggctcgaaa ctttaatatc aatatctcag gtgagacttc agttattatc
    26221 gtttttaccc tctggggaac agctgaaatg ggagacttgg tacgtggagc tatcacttct
    26281 ctccctaaac atcagtttga aagtggacag gcactcggct tgactaatgt tcaactttac
    26341 taccacatca tcatcccaca agtcttgaga agactgctac cgcaggctat caatcttgtc
    26401 actcggatga ttaaaaccac ttcattagtt gttttgattg gggttgtgga agtgaccaaa
    26461 gttggacaac aaatcatcga tagcaatcgc ctgaccatcc caactacttc attttggatt
    26521 tatggaacca ttctaatctt atatttcgca gtttgctacc ctatttccaa actatccact
    26581 cacttagaaa aacattggag aaactaaatg tctgaaacta tcttagaaat caaggaacta
    26641 aaaaaatcct tcggagacaa tcccatcctc caaggacttt ctctagaaat caaaaaaggg
    26701 gaagttgttg tcatcctagg gccatctggt tgtgggaaaa gtaccctcct tcgttgcctc
    26761 aacggcttag aaagtattca aggtggagat attcttctgg atggtcagtc tatcgttgaa
    26821 aataaaaaag attttcacct agttcgccaa aagattggca tggtctttta aagttatgaa
    26881 ctctttcccc atctggatgt cttacaaaac ctcatcctag gccctatcaa aactcaagga
    26941 tgggacaaga aagaagtaac ggaagaagct ttgcaattac tagatcgtgt cggtttgctg
    27001 gataaacaac atagctttgc ccgtcaatta tctggtggac agaagcaacg tgttgcaatt
    27061 gtccgtgccc tcctaatgca tccagaaatc atcctttttg acgaggtgac tgcttcgctg
    27121 gatccagaaa tggtgcgtga ggtgctggaa cttatcaatg atttggccca agaaggccgt
    27181 accatgattt tagtaaccca cgaaatgcag tttgcccaag ccattgctga ccggattatc
    27241 ttcctcgacc aagggaaaat cgctgaagaa ggaacagctc aagccttctt taccaatccg
    27301 caaaccaaac gagcccagga atttttaaac gtctttgact ttagccaatt cggctcatat
    27361 ctataaagga gattcttatg aaactattca aaccactctt aactgtttta gcacttgcct
    27421 ttgcccttat ctttatcact gcttgtagct caggtggaaa cgctggttca tcctctggaa
    27481 aaacaactgc caaagctcgc actatcgatg aaatcaaaaa aagcggtgaa ctgcgaatcg
    27541 ccgtgtttgg agataaaaaa ccgtttggct acgttgacaa tgatggttct taccaaggct
    27601 acgatattga actagggaac caactagctc aagaccttgg tgtcaaggtt aaatacattt
    27661 cagtcgatgc tgccaaccgt gcggaatact tgatttcaaa caaggtagat attactcttg
    27721 ctaactttac agtaactgac gaacgtaaga aacaagttga ttttgccctt ccatatatga
    27781 aagtttctct gggtgtcgta tcacctaaga ctggtctcat tacagacgtc aaacaacttg
    27841 aaggtaaaac cttaattgtc acaaaaggaa cgactgctga gacttatttt gaaaagaatc
    27901 atccagaaat caaactccaa aaatacgacc aatacagtga ctcttaccaa gctcttcttg
    27961 acggacgtgg agatgccttt tcaactgaca atacggaagt tctagcttgg gcgcttgaaa
    28021 ataaaggatt tgaagtagga attacttccc tcggtgatcc cgataccatt gcggcagcag
    28081 ttcaaaaagg caaccaagaa ttgctagact tcatcaataa agatattgaa aaattaggca
    28141 aggaaaactt cttccacaag gcctatgaaa aaacacttca cccaacctac ggtgacgctg
    28201 ctaaagcaga tgacctggtt gttgaaggtg gccattaact cttaaaaggg actggatttt
    28261 aagctccaat ccctttttaa gattttacct ataacatcct gagtctatct aagatgttca
    28321 atctgaacac agtgtacata ctttatcttc tattgcatat actttatcac ataagatacg
    28381 aatatcctct tcactatgac tagcaatcaa aattgttgtc cctttttcac tagagagctt
    28441 tctaaacaat gttctcatat tttctacact tgatttatcc aaggcattca taggttcatc
    28501 tagtaaaaga atagagggat tctccataat tgcttgagca atccctagct ttttcctcat
    28561 acctagcgaa taagttttaa ctttctggtc tttttgctca tatagaccaa ctattttcag
    28621 tgtatcattg atttcctgat taccaactac tcctcgtatg cttgccaaat attgtaaatt
    28681 cttaaagcca ctataataat ttataaaacc aggttcttca atcaaagctc ccaaattagc
    28741 tggaattttt ctctcaggaa caatattttc cccattgatt aacacttctc cataagacgg
    28801 actatataaa ccagctatta atttaaacaa tacacttttc cctgagccat tcgcaccagt
    28861 gattcctatg atttcccctg gtttacaact aaagttaagg ttttgaaaaa cacatgtctt
    28921 ttttaatttc aactcaatat tttttaatat gattatttca ttcattctat aaacctcctc
    28981 ttttgacgag tgaaatagaa aatactttta aaaagaaaga ctaaaaatag caactgaaga
    29041 aataaatctc gtcctatatc tccattccct cgattcaaaa tataaaatag ataattagtt
    29101 cgattcccta caaatagacc accaaacaca atcatgagta aaaagaaact aacgcaagca
    29161 aagttcattt gtacattcgc tcctagtgcg tataacataa agcaaagcaa ggatagcaca
    29221 caagcattca aagaatcaac tataaacaaa actcctatat cccagtttgg taactgtaac
    29281 ataaattgaa tcactagaac ttttaccatg attaaaatga gtccataaag aaaacaggtc
    29341 caaatctgat acctaatcca gagcttaata gaagaaaatc gaatcacttc cataaagaaa
    29401 tcggatgctc ttctacgata tacaactgct agaaaaaatg tatgaataat aaaccaatga
    29461 agcaaccata tggataagac taaaaaagag ttttgactca gattaggccc ttttaaaatt
    29521 tctataacaa gtctatcatt tccttctaac caataccata atcctaaaca aatcaatatc
    29581 caaaaaagaa cataacccca aaagtacttg gtatagatta tctgattcaa cctccacatg
    29641 taactactta actttcccat ttccaacttt tacactctcc tccagtttct atgaacagaa
    29701 aatacagtca atggaattat gatagatagt aatgtaagcc aataaatcaa tgcatacgga
    29761 ttggaattta ccatatactg aaaaattggc aataatccaa ttatcccatt gtccaactga
    29821 taaatccaga ataaggattc tacaaataaa aaagtaaaca gaaatactaa gctcatgttt
    29881 gattttttaa accaagaaaa actgctaata gtaagtaagg ataaaaagaa atagtatgct
    29941 atataagaga aaaaaaatcc tataaagaaa ctagcattgt ttgcaatact tataccataa
    30001 aattctctta aaaaatcaac ctcctttatc tccaaagaga agctaaaacc attactaaat
    30061 gcaattagaa aaatcaataa aaataaagtc gccgtccaaa tccccgtact aagagctgct
    30121 aatttgaaac taaaactggt aaagtgctta attgatttca gacgaatgcg acactccaac
    30181 ctattaaaat agttattcat caaataaaaa aagaacaata tatatgtgaa cggaaagcaa
    30241 tatactccag tcgtcatatc ttgaagtaaa actaagatcc attctaatac atttggatgg
    30301 attgaatatt ggcgacagcg caataaatat actgtactag ataaaacaca ggatagcagt
    30361 aatataaaat aaaccaatac tgctaagaaa tcttttttat aaaattgaac aaattgtttc
    30421 attatacgta gtcctctgaa tgtagaaaaa atgtaccata aacaaccaaa caactaacaa
    30481 ataaaataaa agcaagatgc ccactaacta aggaaagact gatatctttc tgatatccca
    30541 aagctaatgt tgtcacaggt tctaagtaag atagccctaa aatagcccaa aaaataccac
    30601 caaccatcat ataggcaact gggatgaaaa tagctcctat ttttttcttc actagcaaag
    30661 cactagctag tccaaaaata gagaacacag cgccccaaac tccataccag agagtcgtca
    30721 caagactata gagcaactga ttagaatcaa ataattcttt taaggcacca ctataatctc
    30781 caatataaat ttcctgataa ggagtcacta aaagattaat tcctaataat aataaatagg
    30841 ggagaaaaaa gactagaaaa gaagaaataa ttgcagtact acccacaata gctagatacc
    30901 tctttttaga aattcggcac aattgtgctg ttagaaaatg actctcagca tcctctatta
    30961 tctgactaga atagggcagt gtacagataa gtgcagctac taggctaatc ggtgaaaatc
    31021 ctcgaataga agaagcggca aaaaaaatcg ataaaccttc aattttataa ataccattga
    31081 aagcaaggaa atttcctaaa ctcatgcaaa gaagggtcaa aaataaagac atataaaatc
    31141 gaggtgattg aacgactcgt acaagattac aaatgaaaaa ttccatcctt actcctcctt
    31201 ataataaaaa tagggtgtag cattcttttt tcatgctaca cccacaatca accatcttta
    31261 aggcttactc tgacaagtaa gttaataaga atctggactc caagaacctg aagtatgaat
    31321 tcttacatga tttccaaatt gtggcgccat agctaatcta gtaccagaac caatataatt
    31381 gtcaccacct ccattatagt acatgacaat cctagagcca gaccccaatg aatataccgg
    31441 ggtaatatct gacccactat aggcgcgcta cgaatagagg tatttaacct tttaccgcca
    31501 ccagtgctgt cactattatt aattccagca gaggcgtttt ctttctcaag ctcactagtt
    31561 gtatccgaac cccaacgcgg caacgttaaa tcataatttc caatctgtct agctaaaact
    31621 gtagggagaa acaaactaga tgcaattgta actacgcaaa aaaggaatat atttttcttc
    31681 ttttcatgac atcgtcctct taagaagtga taaacaagat agttgattga tcaatttgat
    31741 acatattaca ttttcattat atcaataaaa gaaagcgttg tcaattattt tatttaaaat
    31801 attgtcatat tttaaataaa atggtaaaag aggctcggta gcctcgtctc tctttatctt
    31861 actgacctaa ccttcttgcc aattttcttg gtcgtcttta aagcgtttta gaagatcaag
    31921 gccctctggc gtgatgtaac cttcttcttg ggctagatgg ataagctcgc tatagtttga
    31981 aagcgtcaca agtttaacac cagcatctgc aaagttctta tctgcttttg gcaattggta
    32041 gctgaaaatc gctacaactc caagcacatc tgctccttct cgcttggctg ctgctacagc
    32101 ttcaagaact gaaccacccg ttgaaataag gtcttcaacc actaccattt tttgaccttg
    32161 agctacgcga ccttcgattt gattaccagc tccatggtct tttggtttgc tacggatgta
    32221 ggcaaaaggc aagtccatct tatcagcaat aatggctccg tgtggaatcc ctgctgttgc
    32281 agttcctgca atcacttcta cttcaggaaa ggcttctttg atagcttcca caaaaccatt
    32341 ttcaattagg gtacgagttt ctggataggc tagtgtcaca cgattatcag tgtaaatcgg
    32401 tgacttgata ccagatgccc aagtgaaggg ttcctctggt ttgaggtaaa cggcttggat
    32461 tttcaagagg tggctagcga tatctttagc aagtgtcatg gtattctcct tttatttttc
    32521 taatctagtt ctttaattcc agtcctgtgt ccattcatcc ttgatggcat gataagctgc
    32581 aacaggatcc tcagcttggg taatgggacg tcccactacg atatagtcac tgccgatttg
    32641 ataggcatca gcaggtgtca tgactcgttt ttgatctcca actgcaacac cagctggacg
    32701 aatccctggt gtcagacaga taaaatctgg attggtagcc tgcttgatga cttgtacttc
    32761 ctgagccgag caaacaacac catccaagcc agcttcagct gtcttcttgg catagtgaat
    32821 cacagactct tgcagactgg tttggatatt ttgaaactcc tgcatctgag cttctgacgt
    32881 tgatgtgagc tgagttacag cgatcaattt ggcttgactt ccaagacctt cacgcgcagc
    32941 cttcatcatc tctacaccac cagccgcatg aacattggtc atatccacac caagctgaga
    33001 taggatcttc attgctgact tgactgtatt aggaatgtca tgaagtttga gatccaaaaa
    33061 gacactatga cccaaacctt ttaagtagga cacaatctca ggccccgctg cgtaataaag
    33121 ctccatccct accttgagat aaaggctttc ttctgctggg aaaagagcta aaaattcctt
    33181 gaccgcctca aaactaggaa aatcaagagc aatgattgga cgatgttctc gcataggttt
    33241 ctccttttac ctttactagt gagagagtct ggccaacaga agccacgaaa aaaggaacct
    33301 gccaacagca aggttccacg aaaaatgggt agtctccacc ctttcaccgt ctaaccttag
    33361 ctgcctctct ggactgcttt aaaggttttt taccattcta ttatttctac tagcacttgt
    33421 caagtaaaaa catggtcacg tatgtgttga ctgctattga acacctcaca agactctttc
    33481 caaaagaata gttaaagact ttcacttagg acagagaaaa agagtttgct tgttaccctt
    33541 taattgaaca aatgggaatt ctgttttatt ttgcggatgc ctattcatct tggcaaaggg
    33601 gaagtaatga gaatgcgaat ggacttcttc gtgagtattt tcttaaaccg atttggcaac
    33661 aattaccgaa aaaatcctta atggtgcttt gctagcttat taatcaccgt ccccaaaaat
    33721 acttggatta caagacaggt tttgaagcac ttatagagga gatttaaaaa tgttgcattt
    33781 tttattgcaa tttatcagtt atcttatcac ccaaaacttc tgcaattagt atgagcacta
    33841 ttgttatttt tcttttttcg tacactcaaa tcaaaatata gcaataagac tattctgtag
    33901 aattgctgtc aaaaagatca gttcattttt ccttcccact tgtgtttata atcattaaaa
    33961 taactcaatt aagaaatttt ctttttccta atagttatcg taattaaagt taatagaaga
    34021 acaatccaaa taagtagtgt tagattagga attagagttt cattccatga aaatccctcc
    34081 cattttgtga aaaacttagt aaacagtccc ataaaactat aatctgttat cttcgcaact
    34141 gtcttatcca aaccagatag catcggtaag aaagcaacta aaatcatagc aggaagactg
    34201 ataacctgag ctactacttg gctcttcgcg gttaaaccta tcaataaata gaataaaatg
    34261 atggataaag aggttagaag aacgattgta atataattaa aagtatgtac aattgtaact
    34321 cctaaaataa gaggagtagt tcccataatc acaaaagtta gcaaaaaagg aagaaacatc
    34381 gttgataaaa tgtattcgga tcctttaaca ccactcaaca gaagagtttg taaattgtac
    34441 ttttcttttt cttcagacaa gataatagtt ataggacttc caacagccaa agccaaagaa
    34501 aaaggtaaac acatcatcaa aagaactaat gcctgttgat cgttgacctt cccctgtgtt
    34561 tccataagat atttataaaa atatgtgaaa gcaaaaggca ctaaaacttg caataaaata
    34621 ctcttattgg aaaggataat ttgacaacgc aaccatacca aagccagaaa ccgtttaagc
    34681 atttagcttt cctcctgtta atgtgataaa aatatcttct aaagtaggct cacatgaatg
    34741 aattgaaaaa atattttcca gatcagcctg agatacctgt tctagtgatg taaaatcaaa
    34801 agttatctga ttcccattat aatctgtaac cttaatcttt ttatctttat tatatctttg
    34861 aatgagttca gaaggagctc cttgctcaac taatttccct ttatttaata aggcaacata
    34921 atcacataaa agagttgctt cattcatatc atgagtcgtt agaaaaatcg ttgtccctgc
    34981 tgttttcaat tctaaaatta actcatgaat tgttcgagaa gttgtgggat ctagacctga
    35041 ggtcggttca tccagaaaga gtacagcggg tttgttgata agagctcgtg ctaaaagcat
    35101 tcgttgcctc attccagtgg ataattttcc tgctaccatc ttgcaactat catataatcc
    35161 tactcgcttt aacaaattat caacacgtaa tttactaata ttataaaatt tactataaaa
    35221 aagaagattg ttatacagag acattttctc ataaaatcca cttgtatcgc taaccaatcc
    35281 aattctcttt aattcaccgc ttgttaaatt ttgagatttt tgtcccaaaa taatagattg
    35341 tcctttatcg gcaaggagct gcccagtcag aatattaatc gttgtggtct ttccagaacc
    35401 agatggtcct aaaaatccaa aaatctgacc ttctttaaca gtgaaactta tatcatttaa
    35461 agctatttta tcaccaaaac tttttgataa atggctaact tcaatcatac tcattgcccc
    35521 tcctttatat tctacatttt tacttaacat ctatttactt agctttatca aataaacgtc
    35581 ttaaaaaaaa caataacatt aagcatataa ccgttagcaa gattgtttca atattattga
    35641 taatatgata cattctcaag cagtataaaa taattatata tatgcaaatg ctcattatac
    35701 ctattttttt aaacatacta agcctccttg ctaaataata aagttatata ataactaaga
    35761 cacactatac ctaacataat aaatatccac agcattaaaa atattatcat actaataaaa
    35821 atatccactg gtaactgaat aaatgttcta aaattaacaa gcaaaaataa aatctcaaac
    35881 gatgaaaaaa gccatactat attttccaat gatgtttgaa tatttttatt gtagtaagca
    35941 taatatatag caaaaataat acccaagaac aatactatta attgtgtttc tataacagtg
    36001 aactgcccaa tagcagataa aaaagctact cctcctgata ataagcaaaa acaaactgaa
    36061 cgaataaatg ttttcgctct aatattgtta tctttcactt tattattttt tttacaaatt
    36121 ggacattctc cgttttccag aacatatttt tcttgactta gagcatgatt tctcatatta
    36181 taaacgtaag cgttatctat taggatttca ttataacatc ccagaaatat tttaattatt
    36241 aaattagtca ttatccctcc caaaatagca ggcatctctg gtgtagtcgg ccactttgtc
    36301 ttatcagata aagtgtactt atttatatct ttgtttatat tccgacaagc aaagcaagaa
    36361 ccgatggtag ggatatatat attatcaata ataagatagc atccattaaa ccctcctgat
    36421 atgtaggata tcttatgcga tacagcaaat tgattgacaa tttttataat atcaatgggc
    36481 gtatcaattg ctttaacgat aaaatctata ctcccatatt ccgcaacaat gttttctaat
    36541 tcttctactg aagaaacttt aatagaaata ggtactacct gaacatctga attatacttg
    36601 tgtatttttt gagaaagaac attaatcttc tccttaccaa catccgactc tgtataaaga
    36661 atttgcctat ttaaatttga tggttctatt atatcgtaat cagcgacaat aagtttcctc
    36721 actccataca tacttagact tagagatata taacatccta aggctccggc tcctaatact
    36781 aatactgttt tattctgtat tttattatac tcttcattat aaaataacga atagtaacct
    36841 ttagttctag aatatctact atcaatatct atctcatccg aaattaaaat ttgttcattt
    36901 aatagttcaa atgttagttt actacctaat acttcttcta tctctaatag ttccttacaa
    36961 ctattaaata gatcgttgat aaattcttgc gaaatttgag gttctatagc tatttcccgc
    37021 atactccgac cacgcaaata cattatacct tcttttttat aagcaaaaac ataactattt
    37081 acgtagaaca tatttcgtcc ttcctctcat atataatata gaaagcagta tagaaacaac
    37141 tacccctcct atactacgaa caataatatt aggtgtcaaa aattgtaata gttgactcaa
    37201 agggaaataa ataataacaa atgctattaa aagttgaact atatattgaa aattcaagtt
    37261 attattgtta gaattcaagt atcttaaaat aataccacta tcatactgaa aaaaaggaat
    37321 tgaattaata aaaatcatac ctaagttaat gataaaaaat aagagtccaa gcaatttata
    37381 cgatgtgaac aataaaacaa gtaaacctgt aagtgataaa atcgaatttg aagcaattcc
    37441 tgctaacata attttcaaaa attgtttttt attttttagg aattgcaccc cacttaaatc
    37501 tacaaaaaaa gccaaattaa acaaaagtag cattattcca caatttggga tctcaatttg
    37561 ataattatta gcaattattg catgactaaa ttcatgtatc gttgcagata taataacaac
    37621 aagcaaccaa aataaaagaa tgtttagcgt tattggaaag ttttggaaat tagtcaaaat
    37681 atccgcccta taaatataca taataaaaca ttgcaaaata agagccaatg ggaaaatacc
    37741 aaataggatt ttttcaaaat tctta
//
LOCUS       DAVKMJ010000021        37339 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000021 DAVKMJ010000000
VERSION     DAVKMJ010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37339
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.021"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            201..770
                     /locus_tag="VW348_001091"
     CDS             201..770
                     /locus_tag="VW348_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9745998.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            838..1488
                     /locus_tag="VW348_001092"
     CDS             838..1488
                     /locus_tag="VW348_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HEU9745999.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            1472..3712
                     /locus_tag="VW348_001093"
     CDS             1472..3712
                     /locus_tag="VW348_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEU9746000.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIKKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            3892..4080
                     /locus_tag="VW348_001094"
     CDS             3892..4080
                     /locus_tag="VW348_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746001.1"
                     /translation="MTVTKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGSY"
     gene            4112..4699
                     /locus_tag="VW348_001095"
     CDS             4112..4699
                     /locus_tag="VW348_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9746002.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMTDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            4703..5878
                     /locus_tag="VW348_001096"
     CDS             4703..5878
                     /locus_tag="VW348_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746003.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWKDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKRIF"
     misc_feature    6052..6183
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            6199..6729
                     /gene="infC"
                     /locus_tag="VW348_001097"
     CDS             6199..6729
                     /gene="infC"
                     /locus_tag="VW348_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEU9746004.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            6762..6962
                     /gene="rpmI"
                     /locus_tag="VW348_001098"
     CDS             6762..6962
                     /gene="rpmI"
                     /locus_tag="VW348_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEU9746005.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            7014..7373
                     /gene="rplT"
                     /locus_tag="VW348_001099"
     CDS             7014..7373
                     /gene="rplT"
                     /locus_tag="VW348_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEU9746006.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            7431..7811
                     /locus_tag="VW348_001100"
     CDS             7431..7811
                     /locus_tag="VW348_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9746007.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            8061..8861
                     /locus_tag="VW348_001101"
     CDS             8061..8861
                     /locus_tag="VW348_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEU9746008.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVNQRVCEDGPVFRTGTVVL"
     gene            8824..9810
                     /locus_tag="VW348_001102"
     CDS             8824..9810
                     /locus_tag="VW348_001102"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEU9746009.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            9852..11753
                     /locus_tag="VW348_001103"
     CDS             9852..11753
                     /locus_tag="VW348_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEU9746010.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     AKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWL
                     DKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIP
                     VASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINN
                     SLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYL
                     SAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMK
                     INEKLGGKD"
     gene            complement(11814..13469)
                     /gene="pavA"
                     /locus_tag="VW348_001104"
     CDS             complement(11814..13469)
                     /gene="pavA"
                     /locus_tag="VW348_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEU9746011.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPLANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            13574..14071
                     /gene="ybeY"
                     /locus_tag="VW348_001105"
     CDS             13574..14071
                     /gene="ybeY"
                     /locus_tag="VW348_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEU9746012.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLGYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            14052..14447
                     /locus_tag="VW348_001106"
     CDS             14052..14447
                     /locus_tag="VW348_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEU9746013.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            14464..15363
                     /gene="era"
                     /locus_tag="VW348_001107"
     CDS             14464..15363
                     /gene="era"
                     /locus_tag="VW348_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEU9746014.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            15412..16236
                     /gene="mutM"
                     /locus_tag="VW348_001108"
     CDS             15412..16236
                     /gene="mutM"
                     /locus_tag="VW348_001108"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEU9746015.1"
                     /translation="MPELPEVETVCRCLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQGCVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            16236..16841
                     /locus_tag="VW348_001109"
     CDS             16236..16841
                     /locus_tag="VW348_001109"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEU9746016.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFWQEIILENGELNRPLLASLIFSNPDEREWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            16828..18027
                     /locus_tag="VW348_001110"
     CDS             16828..18027
                     /locus_tag="VW348_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEU9746017.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            18027..18176
                     /gene="rpmG"
                     /locus_tag="VW348_001111"
     CDS             18027..18176
                     /gene="rpmG"
                     /locus_tag="VW348_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU9746018.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            18216..18449
                     /gene="secG"
                     /locus_tag="VW348_001112"
     CDS             18216..18449
                     /gene="secG"
                     /locus_tag="VW348_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEU9746019.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KVRGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            18551..20905
                     /gene="rnr"
                     /locus_tag="VW348_001113"
     CDS             18551..20905
                     /gene="rnr"
                     /locus_tag="VW348_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEU9746020.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAANYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            20868..21335
                     /gene="smpB"
                     /locus_tag="VW348_001114"
     CDS             20868..21335
                     /gene="smpB"
                     /locus_tag="VW348_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEU9746021.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            21351..22211
                     /gene="tehB"
                     /locus_tag="VW348_001115"
     CDS             21351..22211
                     /gene="tehB"
                     /locus_tag="VW348_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEU9746022.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            22284..23237
                     /gene="coiA"
                     /locus_tag="VW348_001116"
     CDS             22284..23237
                     /gene="coiA"
                     /locus_tag="VW348_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEU9746023.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            23256..25058
                     /gene="pepF"
                     /locus_tag="VW348_001117"
     CDS             23256..25058
                     /gene="pepF"
                     /locus_tag="VW348_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU9746024.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEVLKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTFYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGIYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            25060..25773
                     /locus_tag="VW348_001118"
     CDS             25060..25773
                     /locus_tag="VW348_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEU9746025.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELENFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            25840..26781
                     /gene="prsA"
                     /locus_tag="VW348_001119"
     CDS             25840..26781
                     /gene="prsA"
                     /locus_tag="VW348_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEU9746026.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFKKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(26898..27239)
                     /locus_tag="VW348_001120"
                     /pseudo
     CDS             complement(26898..27239)
                     /locus_tag="VW348_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            27652..27747
                     /locus_tag="VW348_001121"
                     /pseudo
     CDS             27652..27747
                     /locus_tag="VW348_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(28000..28620)
                     /locus_tag="VW348_001122"
     CDS             complement(28000..28620)
                     /locus_tag="VW348_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEU9746027.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(28620..29102)
                     /locus_tag="VW348_001123"
     CDS             complement(28620..29102)
                     /locus_tag="VW348_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEU9746028.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(29102..29944)
                     /locus_tag="VW348_001124"
     CDS             complement(29102..29944)
                     /locus_tag="VW348_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEU9746029.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(30039..30839)
                     /locus_tag="VW348_001125"
     CDS             complement(30039..30839)
                     /locus_tag="VW348_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEU9746030.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            30983..32362
                     /gene="glmU"
                     /locus_tag="VW348_001126"
     CDS             30983..32362
                     /gene="glmU"
                     /locus_tag="VW348_001126"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEU9746031.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            32372..32917
                     /locus_tag="VW348_001127"
     CDS             32372..32917
                     /locus_tag="VW348_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9746032.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTARRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            32929..33243
                     /locus_tag="VW348_001128"
     CDS             32929..33243
                     /locus_tag="VW348_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEU9746033.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAAIFLLILLVLAMK
                     LL"
     gene            33260..33952
                     /locus_tag="VW348_001129"
     CDS             33260..33952
                     /locus_tag="VW348_001129"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEU9746034.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            34029..34520
                     /gene="rocS"
                     /locus_tag="VW348_001130"
     CDS             34029..34520
                     /gene="rocS"
                     /locus_tag="VW348_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEU9746035.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            34618..35208
                     /locus_tag="VW348_001131"
     CDS             34618..35208
                     /locus_tag="VW348_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEU9746036.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAD
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            35217..36980
                     /locus_tag="VW348_001132"
     CDS             35217..36980
                     /locus_tag="VW348_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEU9746037.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            37194..>37339
                     /locus_tag="VW348_001133"
     CDS             37194..>37339
                     /locus_tag="VW348_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9746038.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASYVFQISRNTIYGWLKLKEK
                     TGEL"
BASE COUNT        11384 a         6732 c         8237 g        10986 t
ORIGIN      
        1 ttcttttggg attccgatta acattgagat aacctacctt tcaattgacg gtcttgtttt
       61 ggttgtcaca ttccagttca taaatcaaaa atgtgacggt ttcattgtat atgaaaccgc
      121 ttcaaaaatc aagaaaaact tgtcatccaa atttttttat gctagactag tgaaaatcaa
      181 gctctaatgg agggaaaagt atggaatcaa tatttgtgaa atttgcccag tatccgtcta
      241 tagaaacgga gcgtttattg cttagacctg taactttgga tgatgcggaa gcaatgtttg
      301 actatgcctc ggacaagggt aatacacgtt acacttttcc aaccaatcaa agcttggaag
      361 aaaccaagaa taacattgct cagttctact tggctaatcc cttgggacgt tgggggattg
      421 aattaaaaga taacggcaag tttatcggaa ctattgactt acacaagatt gatcctgttc
      481 ttaagaaggc agctattggc tacattatca ataaaaagta ttggaatcaa ggattaacga
      541 cagaagccaa tcgtgctgtg attgagctag cttttgagaa gatagggatg aataagttga
      601 ctgcccttca cgataaggct aatcccgcgt caggaaaggt catggagaaa tcaggcatgc
      661 gtttttccca tgcagaacca tatgcttgta tggaccagca tgaaaaaggc cgaatcgtga
      721 caagagttca ttatgtcttg accaaggaag actattttgc aaataaataa gcagttgaaa
      781 agaaattttt cgactgtttt ttcttcctct tacgaataat ctaagagagg agaaaatatg
      841 gaagcaatta tcgagaaaat caaagagtat aaaatcatcg tcatctgtac tggtctgggc
      901 ttgcttgtag gaggattttt cctgctaaag ccagctccac aaacatctgt caaagagacg
      961 aatttgcagg ctgaagttgc agctgtttcc aaggactcat cgaccggaaa ggaagtgaac
     1021 aaggaagaga aggaagaacc agttgaacaa gatctaatca cagtagatgt caaaggtgct
     1081 gtcaaatcgc cagggattta tgacttgcct gtaggtagtc gagtcaatga tgctgttcag
     1141 aaggctggtg gcttgacaga gcaagcagac agcaagtcgc tcaatctagc tcagaaagtt
     1201 agtgatgagg ctctggttta cgttcctact aagggagaag aagcagttag tcaacagact
     1261 ggttcgggga cagcttcttc aacaagcaag gaaaagaagg tcaatctcaa caaggccagt
     1321 ctggaagaac tcaagcaggt caagggactg ggaggaaaac gagctcagga cattattgac
     1381 catcgtgagg caaatggcaa gttcaagtca gtagacgagc tcaagaaggt ctctggcatt
     1441 ggtgccaaga ccatagaaaa acttaaagac tatgttacag tggattaaga atttctctat
     1501 tcctctaatt tacctgagtt ttctgttact atggctttac tacgccattt tctcagtatc
     1561 ctattttgct ttgttgggtt ttgtttttct gctagtctgc ctctttatcc aatttccttg
     1621 gaaatcagca ggtaaagttc tagtgatttg tggagtcttt ggcttctggt ttctgtttca
     1681 aacttggcaa cagagtcaag tgagtcaaaa tttggtggat tctgttgaaa gggtacggat
     1741 tttaccagac actattaagg ttaacggtga cagtctgtcc tttcgtggta agtctgatgg
     1801 tcgtgctttc caagtctatt ataaactcca gtccgaggag gagaaagaag cctttcaagc
     1861 tttaactgac cttcatgaga taggactaga agggaagctt tcggagccag aagggcagag
     1921 aaattttggt ggctttgact accaaggcta tctgaagact cagggaattt accagacact
     1981 caatattaaa agaatccagt cactccaaaa ggttggcagt tgggatatag gtgaaaacct
     2041 gtccagttta cgtcgaaagg ctgtggtttg gattaagatg cacttcccag accctatgcg
     2101 caattacatg acaggactct tgctaggaca tctggacacc gattttgagg agatgaatga
     2161 gctttattcc agtttaggaa ttattcacct ttttgccttg tcaggtatgc aggtagggtt
     2221 tttcatggac ggatttaaga aactactttt acgattgggc ttgacacaag aaaagttgaa
     2281 gtggctgact tatccctttt cccttatcta tgcgggacta actggatttt cagcatcggt
     2341 tattcgcagt ctcttgcaaa agctactggc tcaacatggg gttaagggct tggataattt
     2401 tgccttgacg gtgcttgtcc tctttattgt catgccaaac tttttcttga cagcaggagg
     2461 agtcttgtcc tgtgcttatg cttttatcct gaccatgacc agcaaagaag gggaggggct
     2521 caaggctgtt actagtgaaa gtctagtcat ctccttgggc atattgccca ttctatcctt
     2581 ctattttgcg gaatttcaac cttggtctat ccttttgacc tttgtctttt cctttctttt
     2641 tgacttggtc ttcttaccgc tcttgtctat cttatttgtc ctttcctttc tctatccagt
     2701 cattcagctg aactttatct ttgaatggtt agagggcatt attcgcttgg tctcgcaggt
     2761 ggcaagtaga ccgcttgtct ttggacaacc caatgaatgg cttttaatcc tattgttaat
     2821 ttctttggct ttggtctatg atttgaggaa aaacattaaa aagctaacgg tattgtgctt
     2881 attgattaca gggctctttc tcctgaccaa gcatccactg gaaaatgaaa tcaccatgct
     2941 ggatgtgggg caaggagaaa gtattttcct acgggatgta actgggaaaa ccattctcat
     3001 agatgtaggt ggtaaggcag aatcttataa gaaaatcaaa aaatggcaag aaaagatgac
     3061 gaccagcaat gcccagcgaa gcttgatacc ctatctcaaa agtcgaggag tagctaagat
     3121 tgaccagcta attttgacta acacggacaa ggagcatgtt ggagatttgt cagagatgac
     3181 caaggctttc catgtagggg agattctagt atcaaaagac agtctgaaac agaaggaatt
     3241 tgtggcagaa ctacaggcga ctcaaacaaa ggtgcgtagt atgatagtag gggagaactt
     3301 gcccattttt ggaagtcagt tagaagttct atctccaagg aaaatgggag atggaggaca
     3361 cgatgatacc ctagttctgt atgggaaatt cttggataag caatttctct tcacgggaaa
     3421 tttggaggag aaaggagaga aggacttgct gaagcactat ccagacttga aagtaaatgt
     3481 tttgaaagct agccaacatg gcaataaaaa atcatcaagt ccagcctttc tagaaaaact
     3541 caaaccagag cttactctta tctcagttgg aaagagcaat cgaatgaaac tcccccatca
     3601 ggaaacattg acacgactgg aaggtatcaa tagcaaagtt tatcgaactg accagcaagg
     3661 agctatacgt tttaaggggt tggatagttg gaaaatcgaa agtgttcgat aggaaggata
     3721 aatgttgtag attagtgaaa taaactaaaa atttgttgca taataatgat aaaaacggca
     3781 taatgaaaac gtattcaata ttgaggatat aaaatcatta aaaatcagca aaagttgttt
     3841 tagttagtta gtttataatc tattggtctt cttcagtcca gtgtatctgc tgtgacagtc
     3901 actaaaagtt acaagtatga ttggaatacg gttttggaat atagtaccaa ctatcacgac
     3961 catcagtatg cttggattcc ggaatggtct cgttattaca gctattctga gtataaagtt
     4021 ggcggaggct ggaactacgc tcgttatgag gtcataaact actatactgg aagttattaa
     4081 tccttaaaga gtgagaaaag gagggctgga tatgttaaat cttactcatg ttaccttaaa
     4141 aacgcgacaa gtcatcttgc aagatgcgga ttttaccttt aaaaagggta ggatttatgg
     4201 ccttcttgct atcaatggct cgggaaagac gacactattc cgagctatga gcaagttgct
     4261 tccccttagt agtggacaca tcgcagttcc tccttctttg ttttattatg agagcgttga
     4321 atggctggat ggaaacttaa gtgggatgga ctaccttcgt ctcataaaaa acatctggaa
     4381 gtcagaccta aacttgagag atgaaatcgc ctactgggaa atgactgact atatcagtct
     4441 tcccatccgc aagtattcct tagggatgaa gcaacgcttg gtgattgcta tgtattttct
     4501 cagtcaggcc aaatgctggc tcatggatga gattacaaat ggcttagacg agtattatcg
     4561 acagaagttt tttgataggc tagcacaaat cgatagacaa gaacagctgg ttcttttaag
     4621 ttcccactat aaggaagagt tggttgatat ctgcgataga gtagtaacca ttcatcaggg
     4681 gcagatagaa gaggtttagt ttatgaaaga tgttagtcta tttttattga aaaaagtttt
     4741 caaaagtcgt ttaaactgga ttatcttagc tttatttgta tctgtactcg gtgttacctt
     4801 ttatttaaat agtcagactg caaactcaca cagcttggag agcaggttgg aaagtcgcat
     4861 tgcagccaac gagagggcta tcaatgaaaa tgaagagaaa ctctcccaaa tgtctgatac
     4921 cagctcggag gaataccagt ttgctaaaaa taatttagac gtgcaaaaaa atcttttgac
     4981 gcgaaagaca gaaattctaa ctttactaaa agaagggcgc tggaaagaag cctactatct
     5041 gcagtggaaa gatgaagaga agaattatga atttgtatca aatgacccga ctgctagctc
     5101 tggcttaaaa atgggggttg accgcgaacg gaagatttac caagccctgt atcccttgaa
     5161 cataaaagca catactttgg agtttccgac ccacgggatt gatcagattg tctggatttt
     5221 agaggttatc atcccaagct tgtttgtggt tgcgattatt tttatgctaa cacaactatt
     5281 tgcagaaaga tatcaaaatc atctggacac agctcactta tatcctgttt caaaagtgac
     5341 atttgcaata tcctctcttg gagttggagt gggatatgta actgtgctgt ttatcggaat
     5401 ctgtggcttt tcttttctag tgggaagtct gataagtggt tttggacagt tagattatcc
     5461 ctacccaatt tatagcttag tgaatcaaga agtaactatt gggaaaatac aagatgtatt
     5521 atttcctggc ttgctcttag ctttcttagc ctttatcgtc attgtggaag ttgtgtactt
     5581 gattgcttac tttttcaagc aaaaaatgcc tgtcctcttt ctttcactca ttgggattgt
     5641 tggcttattg tttggcatcc aaacaattca gcctcttcaa aggattgcac atctgattcc
     5701 ctttacttac ttgcgttcag tggagatttt atctggaaga ttacctaagc agattgataa
     5761 tgtcgatcta aattggagca tgggaatggt cttacttcct tgcctgatta tctttttgct
     5821 attgggaatt ctatttattg aaagatgggg aagttcacag aaaaaaagaa ttttttaata
     5881 gattctagct ttcctatagg tagggaaaat aagtaaaaac taacatagag agggaatcaa
     5941 cttgattctc tctttttgat tcgaaaacca aaccaaaata caaacacaaa cttttcaaaa
     6001 aataactttt tatcttgaca agagctagaa aacttggtat catataaaag ttgagaaaag
     6061 cagaagtgag agcttctcgc cttgtgacat taagttgcct ggccctacgg atgaaaagtt
     6121 tcgaagaaac gctatcataa cgtgcgggct tgtatattta cgagtccgct attgtttttc
     6181 tctaataaaa caaaagaggt gaaaaccata gcaaagcaag acttattcat caatgatgag
     6241 attcgtgtac gtgaagttcg cttgattggt cttgaaggag aacagctagg catcaagcca
     6301 ctcagtgaag cgcaagcttt ggctgataac gctaatgttg acctagtatt gattcaaccc
     6361 caagccaaac cgcctgttgc aaaaattatg gactacggta agttcaaatt tgagtaccag
     6421 aagaagcaaa aagaacaacg taaaaaacaa agcgttgtta ctgtgaaaga agttcgtcta
     6481 agtccaacta ttgacaaggg tgactttgat acaaaacttc gtaatgcacg taagttcctt
     6541 gaaaaaggaa ataaagttaa ggtatctatt cgctttaagg gtcgtatgat tacccataaa
     6601 gagattggtg caaaagtttt agccgagttt gctgaagcaa ctcaagatat tgccatcatc
     6661 gaacaacgtg ctaaaatgga tggacgtcaa atgttcatgc aattggcgcc agcgactgac
     6721 aaaaaataat tgtcagaaag ttaaataaag gagaaaaaat tatgccaaaa caaaaaacac
     6781 accgcgcatc agctaaacgt ttcaaacgta caggttctgg tggacttaaa cgtttccgtg
     6841 cttacacttc tcaccgtttc cacggaaaaa ctaagaaaca acgtcgtcat cttcgtaaag
     6901 catctatggt gcattcagga gattacaaac gtatcaaagc aatgcttact cgcttgaaat
     6961 aatagcttga ctgtaagtaa acaattctag gaaatatttg gaggaaataa aacatggcac
     7021 gtgttaaagg tggcgttgta tcacgcaaac gtcgtaaacg tattcttaaa ttagcaaaag
     7081 gttactatgg agctaaacac atcttgttcc gtactgcaaa agaacaagta atgaactctt
     7141 actactatgc ataccgtgac cgtcgtcaga aaaaacgtga cttccgcaaa ttgtggatca
     7201 ctcgtatcaa tgcggcagct cgtatgaacg gactttcata ctcacaattg atgcatggtt
     7261 tgaaattggc tgagatcgaa gttaaccgta aaatgcttgc tgacttggct gttaacgatg
     7321 cagtagcttt cacagctctt gcagatgcag ctaaagcaaa acttggtaaa taacaactga
     7381 tgagactgga acaggattgt ccagtctttt taaaaataaa ggagaaaaat atggcttcaa
     7441 aaatgctaca cacttgctta cgagtagaaa atcttgaaaa atcaatcgca ttttatcaag
     7501 atgcttttgg ttttaaagaa ttgcgtcgca gagattttcc agaccatgcc ttcacgattg
     7561 tctatctagg tcttgagggt gatgactatg agttggagtt gacttataac tacgatcacg
     7621 gtccgtatgt ggttggtgat gggtttgccc atatcgccct cagtacacct gatcttgagg
     7681 cacttcatca agaacacagt gcaaaaggct atgaagtgac tgagccaaat ggtctaccag
     7741 gaactacacc aaactattac tttgtcaaag accctgatgg atataaggtc gaagtcattc
     7801 gtgaaaaata atttcgtgca agttaagtag aatattcgtt ttttacttga ctttttttag
     7861 ctgaaagagt atactaataa aaattcaacc tttaagggga gtccagagag actcacaagg
     7921 tgtcagataa aagaatagtg caattttcta gaggagactt tttgagtgtg ctctcttgtg
     7981 ttgtacgatt ttaactgagg ccttgcacta gcaaggtctt ttctttatct ggtcccctta
     8041 aaatttaagg aggaaaagtt atgaatccca catgtaagaa gcgtttgggt gtcattcggt
     8101 tggaaaccat gaaggtggtt gcacaagagg aaatcgcgcc agcaatcttt gaattagtcc
     8161 tagaaggaga aatggttgaa gccatgcgag caggccaatt tcttcatctg cgtgtaccag
     8221 acgatgccca tcttttacgt cgtcctattt caatttcgtc tattgacaag gcaaacaagc
     8281 agtgtcacct catttatcgg attgagggag ctgggactgc aattttttca accttaagtc
     8341 agggagacac tcttgatgtg atggggcctc agggaaatgg ttttgacttg tctgaccttg
     8401 atgagcagaa tcaggttctc cttgttggtg gtgggattgg tgttccaccc ttgcttgagg
     8461 tggccaagga attgcatgaa cgtggagtga aagtagtgac agtcctcggt tttgctaata
     8521 aggatgctgt tattttgaaa acggaattgg ctcagtatgg tcaggtcttt gtaacgacag
     8581 atgatggttc ttatggcatc aagggaaatg tttccgttgt tatcaatgat ttagatagtc
     8641 agtttgatgc tgtttactcg tgtggggctc caggaatgat gaagtatatc aatcaaacct
     8701 ttgatgatca cccaagagcc tatttatctc tggaatctcg tatggcttgt gggatgggag
     8761 cttgctatgc ctgtgttcta aaagtaccag aaagcgagac ggtcaaccaa cgcgtctgtg
     8821 aagatggtcc tgttttccgc acaggaacag ttgtattata aggagaaaat tatgactaca
     8881 aatcgattac aagtgtctct acctggtttg gatttgaaaa atccgattat tccagcatca
     8941 ggttgttttg gctttggaca agagtatgcc aagtactatg atttaaacct tttaggttct
     9001 attatgatca aggcgacaac ccttgaacca cgttttggga acccaactcc aagagtagca
     9061 gagacgcctg ctggtatgct caatgcaatt ggcttgcaaa atcctggttt agaggttgtt
     9121 ttggctgaaa agctaccttg gctggaaaga gaatatccaa atcttcctat tattgccaat
     9181 gtagctggtt tttcaaaaca agagtatgca gctgtttctc atgggatttc caaggcaact
     9241 aatgtaaaag ctatcgagct caatatttct tgtcccaatg ttgaccactg taatcatgga
     9301 cttttgattg gtcaagatcc agatttggct tatgatgtgg tgaaagcagc tgtggaagcc
     9361 tcagaagtgc cagtttatgt caaattaacc ccgagtgtga ccgatatcgt tactgtcgca
     9421 aaagctgcag aagatgcggg agcaagtggc ttgaccatga tcaatactct ggttggaatg
     9481 cgctttgacc tcaaaaccag aaaaccaatc ttggccaatg gaacaggtgg aatgtcaggt
     9541 ccagcagtct ttccagtagc cctcaaactc atccgccaag tagcccaaac aacagacctg
     9601 cctatcattg gaatgggggg agtggattcg gctgaagctg ccctagaaat gtatctggct
     9661 ggggcatctg ctatcggagt tggaacagct aactttacca atccttatgc ctgccctgac
     9721 atcatcgaaa atttaccaaa agtcatggat aaatacggta ttagcagtct ggaagaactc
     9781 cgtcaggaag taaaagagtc tctgaggtaa actgcaatca atctgttctt gattttttat
     9841 tagtttgtaa tatgaattta ggagaatttt ggtacaataa aataaataag aacagaggaa
     9901 gaaggttaat gaagaaagta agatttattt ttttagctct gctatttttc ttagctagtc
     9961 cagagggtgc aatggctagt gatggtactt ggcaaggaaa acagtatctg aaagaagatg
    10021 gcagtcaagc agcgaatgag tgggtttttg atactcatta tcaatcttgg ttctatataa
    10081 aagcagatgc taactatgct gaaaatgaat ggctaaagca aggtgacgac tatttttacc
    10141 tcaaatctgg tggctatatg gccaaatcag aatgggtaga agacaaggga gccttttatt
    10201 atcttgacca agatggaaag atgaaaagaa atgcttgggt aggaacttcc tatgttggtg
    10261 caacaggtgc caaagtaata gaagactggg tctatgattc tcaatacgat gcttggtttt
    10321 atatcaaagc agatggacag cacgcagaga aagaatggct ccaaattaaa gggaaggact
    10381 attatttcaa atccggtggt tatctactaa caagtcagtg gattaatcaa gcttatgtga
    10441 atgctagtgg tgccaaagta cagcaaggtt ggctttttga caaacaatac caatcttggt
    10501 tttacataaa agaaaatgga aactatgctg ataaagaatg gattttcgag aatggtcact
    10561 attattatct aaaatctggt ggctacatgg cagccaatga atggatttgg gataaggaat
    10621 cttggtttta tctcaaattt gatgggaaaa tagctgaaaa agaatgggtc tacgattctc
    10681 atagtcaagc ctggtactac ttcaaatccg gtggttacat gacagccaat gaatggattt
    10741 gggataagga atcttggttt tacctcaagt ctgatggcaa aatggctgaa aaagaatggg
    10801 tctacgattc tcatagtcaa gcctggtact acttcaaatc tggtggttac atggcgaaaa
    10861 atgagacagt agatggttat cagcttggaa gcgatggtaa atggcttgga ggaaaagcta
    10921 caaatgaaaa tgctgcttac tatcaagtag tgcctgttac agccaatgtt tatgattcag
    10981 atggtgaaaa gctttcctat atatcgcaag gtagtgtcgt atggctagat aaggatagaa
    11041 aaagtgatga caagcgcttg gctattacta tttctggttt gtcaggctat atgaaaacag
    11101 aagatttaca agcgctagat gctagtaagg actttatccc ttattatgag agtgatggcc
    11161 accgttttta tcactatgtg gctcagaatg ctagtatccc agtagcttct catctttctg
    11221 atatggaagt aggcaagaaa tattattcgg cagatggcct gcattttgat ggttttaagc
    11281 ttgagaatcc cttccttttc aaagatttaa cagaggctac aaactacagt gctgaagaat
    11341 tggataaggt atttagtttg ctaaacatta acaatagcct tttggagaac aagggcgcta
    11401 cttttaagga agccgaagaa cattaccata tcaatgctct ttatctcctt gcccatagtg
    11461 ccctagaaag taactgggga agaagtaaaa ttgccaaaga taagaataat ttctttggca
    11521 ttacagccta tgatacgacc ccttaccttt ctgctaagac atttgatgat gtggataagg
    11581 gaattttagg tgcaaccaag tggattaagg aaaattatat cgatagggga agaactttcc
    11641 ttggaaacaa ggcttctggt atgaatgtgg aatatgcttc agacccttat tggggcgaaa
    11701 aaattgctag tgtgatgatg aaaatcaatg agaagctagg tggcaaagat tagtactata
    11761 agtgaatatg atttgagtga atagtaagtt aaaaatcctg atttcaagta aaatcaggat
    11821 tttttcatgg atgcaatttt tttggagtct ggtgtgacgc ggagggtctt ttgtcctgtg
    11881 taagtgacaa agccgggttt tccaccagtt ggtttattga gttttttgac ttcaatcata
    11941 tctacctgca ccagattcga caggcgccct tgagagaagt aggcagctaa ctctgctgcg
    12001 tctgtcttga ctgcatcaga tgggtcaaga tttcctgaga tgacaacatg gcttccagga
    12061 atgtccttag catggaacca aagttcctcc ttgcgggcca ttttaaaggt caattcctca
    12121 ttttgaagat tgtttcgtcc gacatagatg atggttttgc catcgcttgc tagatattgt
    12181 tctagttttt tgcgtttctg gattttctcc cgttgtcttc tgcggataaa acctgtttga
    12241 atcaattctt cacggatttc agcgatttct tccagtccag cttggttgag gacggtttct
    12301 acactttcca gatagagaat agtggctttg gtttcttcaa tcaaatcagt caagtatttg
    12361 acagcttctt tgagtttctg ataccgttta aaatagcgtt gggcattctg gttgggagtc
    12421 agagccttat caagcgcaat catgataggt tggttggtat agtagttgtc taggataacc
    12481 tggtcttggt cgttaggcac ttggtggagg aaggttgtca gcaattctcc tttttgacga
    12541 aattcttcag cgttgtctgt cgccagtaac tctttttcct gttttttgag tttgtgtcgg
    12601 tttttctgaa gttcattttc aacacgacga atcagttcac tggcctgctg tttgacgcgg
    12661 tcgcgctcag ccttatcctt atagtaggtg tccaacaaat cagaaagatt tgcaagaggc
    12721 tctcccacct gatttgcaaa aggaactgga ctgaaggaag tctcagtcaa gcatggcttg
    12781 gtttcttgat tgaaaaaatt tcggaaagcg gaaagttttt cactaaccag tatcctttcc
    12841 aattcatttg ccgtatcgcg tcccagacct tgaaagaggc tttgaagatt ttttgctgtt
    12901 agttcttggg tttgcaggat ttcaaagagc ttttcatcct tgatagtaaa aggattgaga
    12961 gattttgtac ttggcggagc gatataggtc gatcctggaa gtaaggtgcg gtagctattt
    13021 tgtgaaaagc cgacgtgttt gataacttcg aggattttat gactgctttt atcgaccagt
    13081 agaatattac tgtgtttccc cataatttcg ataatcaagg tagcctggat atggtctcca
    13141 atctcgtttt tattggaaac tgtaatttcc acaatacggt cattttccac ttgctcaatc
    13201 gactcaatca gggccccctg caaatacttt ctcaaaacca tgataaaggt agaaggttgg
    13261 gctggatttt caaaagtcgt ttgggtcagc tgaatgcgtc caaaaactgg atgggcagaa
    13321 aggagcaggc gatggctttg gcgattgctg cggatttgca agaccaactc ttgttcaaaa
    13381 ggctgattga ttttctggat gcgaccattc actaattcgc ttcgcaattc ctcaactatg
    13441 tggtgtaaaa aaaatccgtc aaatgacatc gttctctcct tgtgattgta ttccatagta
    13501 ttatatcaaa aaggtagaat aaaatcatgg aaatgtggta taataaagcc aagtaaagag
    13561 aaacgagaag cacatgtata ttgaaatggt agatgaaact ggtcaagttt caaaagaaat
    13621 gttgcaacaa acccaagaaa ttttggaatt tgcagcccaa aaattaggaa aagaagacaa
    13681 ggagatggca gtcacttttg tgaccaatga gcgtagtcat gaacttaatc tggggtaccg
    13741 tgacaccgac cgtccgacag atgtcatcag ccttgagtat aaaccagaat tggaaattgc
    13801 ctttgacgaa gaggatttgc ttgaaaatcc agaattggca gagatgatgt ctgagtttga
    13861 tgcctatatt ggggaattgt tcatctctat cgataaggct catgagcagg ccgaagaata
    13921 tggtcacagc tttgagcgtg agatgggctt cttggcagta cacggctttt tacatattaa
    13981 cggctatgat cactatactc cggaagaaga agcggagatg ttcggtttac aagaagaaat
    14041 tttgacagcc tatggactca caagacaata aacgaaaatg gaaaaatcgt gacctgatat
    14101 ccagtttaga atttgccatc acagggattt ttactgctat caaggaagaa cgcaatatgc
    14161 gaaaacatgc agtgacggct ctagtggtca tccttgcagg ttttggtttt caggtgtcac
    14221 gaatcgaatg gctctttctc ctattgagca ttttcttggt ggtagccttt gaaattatca
    14281 attctgctat cgaaaatgtg gtggatttgg ccagtcacta tcacttttcc atgctggcta
    14341 aaaatgccaa ggatatggcg gctggcgcgg tattagtggt ttctcttttt gcagccttaa
    14401 caggcgcatt gatttttctc ccacgaatct gggatttatt attttaaaca gtaagaggaa
    14461 attatgactt ttaaatcagg ctttgtagcc attttaggac gtcccaatgt tgggaagtca
    14521 acctttttaa atcacgttat ggggcaaaag attgccatca tgagtgacaa ggcgcagaca
    14581 acgcgcaata aaatcatggg aatttacacg actgataagg agcaaattgt ctttatcgac
    14641 acaccaggga ttcacaaacc taaaacagct ctcggagatt tcatggttga gtctgcctac
    14701 agtacccttc gcgaagtgga cactgttctt ttcatggtgc ctgctgatga agcgcgtggt
    14761 aagggggacg atatgattat cgagcgtctc aaggctgcca aggttcctgt gattttggtg
    14821 gtgaataaaa tcgataaggt ccatccagac cagctcttgt ctcagattga tgacttccgt
    14881 aatcaaatgg actttaagga aattgttcca atctcagccc ttcagggaaa taacgtgtct
    14941 cgtctagtgg atattttgag tgaaaatctg gatgaaggtt ttcaatattt cccgtctgat
    15001 caaatcacag accatccaga acgtttctta gtttcagaaa tggttcgcga gaaagtcttg
    15061 cacctaactc gtgaagagat tccgcattct gtagcagtag ttgttgactc tatgaaacgg
    15121 gacgaagaga cagacaaggt tcacatccgt gcaaccatca tggtcgagcg cgatagccaa
    15181 aaagggatta tcatcggtaa aggtggcgct atgcttaaga aaatcggtag catggcccgt
    15241 cgtgatatcg aactcatgct aggagacaag gtcttcctag aaacctgggt caaggtcaag
    15301 aaaaactggc gcgataaaaa gctagatttg gctgactttg gctataatga aagagaatac
    15361 taagtagagg tgggctcatg cctgcttctt gtttttacag aaggaggact tatgcctgaa
    15421 ttacctgagg ttgaaaccgt ttgtcgttgc ttagaaaaat tgattatagg aaagaagatt
    15481 tcgagtatag aaattcgcta ccccaagatg attaagacgg atttggaaga gtttcaaagg
    15541 gaattgccta gtcagattat cgagtcaatg ggacgtcgtg gaaaatattt gcttttttat
    15601 ctgacagaca aggttttgat ttcccatttg cggatggagg gcaagtattt ttactatcca
    15661 gaccaaggac ctgaacgcaa gcatgcccat gttttctttc attttgaaga tggtggcacg
    15721 cttgtttatg aggatgttcg caagtttgga accatggaac tcttggtgcc tgacctttta
    15781 gacgcctact ttatttctaa aaaattaggt cctgaaccaa gcgaacaaga ctttgattta
    15841 caggtctttc aatctgccct tgccaagtcc aaaaagccta tcaaatccca tctcctagac
    15901 cagaccttgg tagctggact tggcaatatc tatgtggatg aggttctctg gcgagctcag
    15961 gttcatccag ctagatcttc ccagactttg acagcagaag aagcgacagc tattcatgac
    16021 caaaccattg ctgttttgag ccaggctgtt gaaaaaggcg gttccaccat tcggacctat
    16081 accaatgcct ttggggaaga tggaagcatg caggattttc atcaggtcta tgataagact
    16141 ggtcaaggat gtgtacgctg tggtaccatc attgagaaaa ttcaactagg tggacgtgga
    16201 acccactttt gtccaaactg tcaaaggagg gactgatggg aaaaatcatc ggaatcactg
    16261 ggggaattgc ctctggtaag tcaactgtga caaattttct aagacagcaa ggctttcaag
    16321 tagtggatgc cgacgcagtc gtccaccaac tacagaaacc tggtggtcgt ctgtttgagg
    16381 ctctagtaca gcacttttgg caagaaatca ttcttgaaaa cggagaactc aatcgccctc
    16441 tcctagctag tctcatcttt tcaaatcctg atgaacgaga atggtctaag caaattcaag
    16501 gggagattat ccgtgaggaa ctggctactt tgagagaaca gttggctcag acagaagaga
    16561 ttttcttcat ggatattccc ctactttttg agcaggacta cagcgattgg tttgctgaga
    16621 cttggttggt ctatgtggac cgagatgccc aagtagaacg cttaatgaaa agggaccagt
    16681 tgtccaaaga tgaagctgag tctcgtctgg cagcccagtg gcctttagaa aaaaagaaag
    16741 atttggccag ccaggttctt gataataatg gcaatcagaa ccagcttctt aatcaagtgc
    16801 atatccttct tgagggaggt aggcaagatg acagagatta actggaagga taatctgcgc
    16861 attgcctggt ttggtaattt tctgacagga gccagtattt ctttggttgt accttttatg
    16921 cccatcttcg tggaaaatct aggtgtaggg agtgagcaag tcgcttttta tgcaggctta
    16981 gcaatttctg tctctgctat ttccgcggcg ctcttttctc ctatttgggg tattcttgct
    17041 gacaaatacg gccgaaaacc catgatgatt cgggcaggtc ttgctatgac tatcactatg
    17101 ggaggcttgg cctttgtccc aaatatctat tggttaatct ttcttcgttt actaaacggt
    17161 gtatttgcag gttttgttcc taatgcaacg gcactgatag ccagtcaggt tccaaaggag
    17221 aaatcaggct ctgccttagg tactttgtct acaggcgtag ttgcaggtac tctaactggt
    17281 ccctttattg gtggctttat cgcagaatta tttggcattc gtacagtttt cttactggtt
    17341 ggtagttttc tatttttagc tgctattttg actatttgct ttatcaagga agattttcaa
    17401 ccagtagcca aggaaaaggc tattccaaca aaggaattat ttacctcggt taaatatccc
    17461 tatcttttgc tcaatctctt tttaaccagt tttgtcatcc aattttcagc tcaatcgatt
    17521 ggccctattt tggctcttta tgtacgcgat ttagggcaga cagagaatct tctttttgtc
    17581 tctggtttga ttgtgtccag tatgggcttt tccagcatga tgagtgcagg agtcatgggc
    17641 aagctaggtg acaaggtggg caatcatcgt ctcttggttg tcgcccagtt ttattcagtc
    17701 atcatctatc tcctctgtgc caatgcctct agcccccttc aactaggact ctatcgtttc
    17761 ctctttggat tgggaaccgg tgccttgatt cccggggtta atgccctact cagcaaaatg
    17821 actcccaaag ccggcatttc gagggtcttt gccttcaatc aggtattctt ttatctggga
    17881 ggtgttgttg gtcccatggc aggttctgca gtagcaggtc aatttggcta ccatgctgtc
    17941 ttttatgcga cgagcctttg tgttgccttt agttgtctct ttaacctgat tcaatttcga
    18001 acattattaa aagtaaagga aatctagtgc gagtaaaaat taatctcaaa tgctcctctt
    18061 gtggcagtat caattaccta accagtaaaa attcaaaaac ccatccagac aagattgagg
    18121 ttttaaagta ttgtcccaag gaaagaaaag taaccctaca tcttgaatct aagtagattt
    18181 tatggtaaaa taatagggat tttaaggagt ttgatatgta taacctatta ttaaccattt
    18241 tattagtatt atctgttgtg attgtgattg caattttcat gcaaccaacc aaaaaccaat
    18301 ccagcaatgt atttgatgcc agttcaggtg atttgtttga acgtagtaaa gttcgcggtt
    18361 ttgaagctgt aatgcagcgt ttgacaggga ttttagtctt tttctggcta gccattgcct
    18421 tagcattgac ggtattatca agtagataag aaaataatgg gcaggactag gtctttgcct
    18481 ctttttattt ttaaaggatg tttgagaagg ttttacagta aaagaaaatt aaaaaatcta
    18541 gaaagaaaat atgaaagata gaataaaaga atatttacaa gacaagggaa aggtgactgt
    18601 taatgatttg gctcaggctt tgggaaaaga cagttccaag gattttcgtg agttgattaa
    18661 aaccttgtcc ttaatggaaa gaaagcacca aattcgtttt gaagaagatg gtagtctgac
    18721 attagaaatt aagaaaaaac atgagattac cctcaagggg atttttcatg cccataaaaa
    18781 tggctttggc tttgttagtc tggaaggcga ggaggacgac ctttttgtag ggaaaaatga
    18841 tgtcaactat gctattgatg gtgataccgt cgaggtagtg attaagaaag tcgctgaccg
    18901 caataaggga acagcagcag aagccaaaat tattgatatc ctagaacaca gtttgacaac
    18961 agttgtcggg caaatcgttc tggatcagga aaaacctaag tatgctggct atattcgttc
    19021 aaaaaatcag aaaatcagtc aaccgattta tgttaagaaa ccagccctaa aattagaagg
    19081 aacagaagtt ctcaaagtct ttatcgataa atacccaagc aagaaacatg atttctttgt
    19141 cgcgagtgtt ctcgatgtag tgggacactc aacggatgtc ggaattgatg ttcttgaggt
    19201 cttggaatca atggacattg tatccgagtt tccagaagct gttgttaagg aagcagaaag
    19261 tgtgcctgat gctccgtctc aaaaggatat ggaaggtcgt ctggatctaa gagatgaaat
    19321 tacctttacc attgacggtg cggatgccaa ggacttggac gatgcagtgc atatcaaggc
    19381 tctgaaaaat ggcaatctgg agcttggggt tcacatcgca gatgtttctt attatgtgac
    19441 cgaggggtct gcccttgaca aggaagccct taaccgtgcg acttctgttt acgtgacaga
    19501 ccgagtggtg ccaatgcttc cagaacgact atcaaatggc atctgctctc tcaatcccca
    19561 agttgaccgc ctgacccagt ctgctattat ggagattgat aaacatggtc gtgtggtcaa
    19621 ctataccatt acacaaacag ttatcaagac cagttttcgt atgacctata gcgatgtcaa
    19681 tgatatccta gctggcgatg aagaaaagag aaaagaatat cataaaattg tatcaagtat
    19741 cgaactcatg gccaagcttc atgaaacttt agaaaacatg cgtgtgaaac gtggagctct
    19801 caattttgat accaatgaag cgaagatttt agtggataaa caaggtaagc ctgttgatat
    19861 cgttcttcgg cagcgtggta ttgccgagcg gatgattgag tcttttatgt tgatggctaa
    19921 tgaaacagtt gccgaacatt tcagcaagtt ggatttgcct tttatctatc gaattcacga
    19981 ggagcctaag gctgaaaagg ttcagaagtt tattgattat gcttcgagtt ttggcttgcg
    20041 catttatgga actgccagtg agattagtca ggaggcactt caagacatca tgcgtgctgt
    20101 tgagggagaa ccttatgcag atgtattgtc catgatgctt cttcgctcta tgcagcaggc
    20161 tcgttattcg gagcacaatc acggccacta tggactagct gctaactatt atactcactt
    20221 taccagtcca attcgtcgtt atccagacct tcttgttcac cgtatgattc gggattacgg
    20281 ccgttctaag gaaatagcag agcattttga acaagtgatt ccagagattg cgacccagtc
    20341 ttccaaccgt gaacgtcgtg ccatagaagc tgagcgtgaa gtcgaagcca tgaaaaaggc
    20401 tgagtatatg gaagaatacg tgggtgaaga gtatgatgca gttgtatcaa gtattgtcaa
    20461 attcggtctc tttgtcgaat tgccaaacac agttgaaggc ttgattcaca tcactaatct
    20521 acctgaattt tatcatttca atgagcgtga tttgactctt cgtggagaaa aatcaggtat
    20581 cactttccga gtgggtcagc agatccgtat ccgtgttgaa agagcggata aaatgactgg
    20641 agagattgat ttttcattcg tacctagtga gtttgatgtg attgaaaaag gcttgaaaca
    20701 gtctagtcat agtggcagag ggcgtggttc aaatcgtcgt tcggataaga aggaagacaa
    20761 gagaaaatca ggacgctcaa atgataagcg taagcattca caaaaagaca agaagaaaaa
    20821 aggaaagaaa cctttttaca aggaagtagc taagaaagga gccaagcatg gcaaagggcg
    20881 agggaaaggt cgtcgcacaa aataaaaagg cacgccacga ctatacaatc gtagatacgc
    20941 tagaggcagg gatggtcctg actggaactg aaatcaagag tgtacgagct gctcgaatta
    21001 atctcaagga tggctttgct caagtgaaaa atggagaagt ttggctgagc aatgttcata
    21061 tcgcgcctta cgaagagggc aatatctgga accaggaacc agaacgtcgt cgtaaactcc
    21121 tgctccataa aaagcaaatt caaaaattgg aacaagagac caaagggaca ggaatgacct
    21181 tagttcccct taaggtctat ataaaagatg gctacgctaa gcttctttta ggacttgcca
    21241 aagggaagca tgactatgac aaacgggagt ctatcaaacg tcgtgagcaa aatcgagata
    21301 tcgcgcgtgt gatgaaagct gttaatcagc gataaaaaga ggaattgaaa atggaaaaat
    21361 tagttgccta taaacgcatg cctttgtgga ataaacaaac aatgcctgaa gctgttcagc
    21421 aaaagcacaa tacaaaagtt gggacttggg ggaaaattac tgtcttgaag ggagctctca
    21481 agtttattga attgacagaa gaaggggaag ttctagctga acacctcttt gaagcagggg
    21541 cagacaatcc aatggcccaa cctcaagcct ggcaccgagt ggaagctgcc acagatgatg
    21601 tggaatggta cttggaattt tattgtaaac ctgaggatta ttttgctaaa aaatacaata
    21661 ccaatcctgt tcattcagag gtcctagagg ccatgcagac agtgaaacaa gggaaagctt
    21721 tggatttggg ttgtggtcag gggcgtaatt ctctttttct agcccagcaa gattttgatg
    21781 tgacggctgt agatcaaaat ggactagctc ttgaaatctt gcaaagcatt gtggagcagg
    21841 aagatttgga catgcctgtt ggcctttacg atatcaattc agctagcatt gaacaagaat
    21901 atgattttat cgtttcaaca gttgttctca tgtttctaca agcggaccgc attccagcta
    21961 ttattcaaaa tatgcaggag aaaaccagtg ttggtggtta caaccttatc gtttgtgcca
    22021 tggacacgga ggattatcct tgctcggtta atttcccatt cacctttaaa gaaggagaac
    22081 tggcagacta ttacaaggat tgggaattgg ttaagtacaa tgaaaatcca ggccatttgc
    22141 accgtcgcga tgagaatggc aatcgtattc aactacgctt tgcgacctta ctagctaaga
    22201 aaatcaagta aacacacatg aagattagga attttcctga tcttttttct tttttacgaa
    22261 tgatatagaa aaggagggaa ttcatgtttg ttgcgagaga tgctagggga gaattggtaa
    22321 atgtgttaga ggataaactt gagaagcaag catacacctg cccagcttgt ggaggccagc
    22381 tccatttgcg tcaaggacca agtgtacgga cgcattttgc ccataaatcc ttaaaagact
    22441 gtgatttttt ctttgaaaat gaaagtccag aacacctggc caataaggaa tccctctatc
    22501 actggttgaa aaaagagaca aaggttcaat tagagtaccc gctttcagaa cttaaacaga
    22561 ttgcggatgt atttgtaaat ggcaatctag ctctagaagt tcagtgtagt cccttgcctc
    22621 agaaagtcct taaagagcga agtgagggat atcgtagtca gggttaccaa gtactgtggt
    22681 tgctgggtca aaaactgtgg ctcaaggagc gtttgactcg tctacagcaa ggttttcttt
    22741 atttcagtca aaacatgggc ttttatgttt gggaattaga caaggaaaaa caagttttaa
    22801 gactcaaata cctgatttac caggatctcc gcggtaaact ccattatcaa atcaaggaat
    22861 tttcctatgg tcaaggtagt ttattggaaa tattgcgtct tccctataag aaacaaaaaa
    22921 tatctcattt tacagtttct gaggacaagg acatctgtcg ctatatccgg caacaacttt
    22981 attatcaaaa tctcttttgg atgaaagaac aagcagaagc ctatcaaaag ggagaaaata
    23041 tcctgactta tggactgaaa gaatggtatc cacaaattcg accaatagtg ggcaaatttt
    23101 tccagattga acaagacttg actagctatt atcagcactt ttatacctat taccaaaaaa
    23161 atcctcaaaa tgattggcaa aagctttatc caccagcctt ttatcagcaa tatttcttga
    23221 aaaatatggt agaatagaaa ggatggagga atctaatggt attacaaaga aatgaaataa
    23281 atgaaaaaga tacatgggat ctatcaacga tctacccaac tgaccaggct tgggaagaag
    23341 tcttaaaaga tttaacagaa caattggaga cagtagccca gtatgaaggc catctcttgg
    23401 atagtgcgga taacctacta gaaatcactg aattttctct tgaaatggaa cgccagatgg
    23461 agaagcttta cgtttatgct catatgaaga atgaccagga tacacgtgaa gctaagtatc
    23521 aagagtacta tgccaaggcc atgacattct acagccagtt agaccaagcc ttttcattct
    23581 atgagcctga atttatggag attagcgaaa agcagtatgc tgacttttta gaagctcaac
    23641 caaagctgca ggtttatcaa cactattttg acaagctctt gcaaggcaag gatcacgttc
    23701 tctcacaacg tgaagaagaa ttattggctg gagctggaga aatctttggt tcagcaagtg
    23761 aaaccttcgc tatcttggac aatgcggata ttgtgttccc ttatgtccta gacgatgatg
    23821 gtaaagaagt tcagctatct catgggattt acacacgttt gatggagtct aaaaaacgtg
    23881 aggttcgccg tggtgcctat caagctcttt atgcgactta cgaacaattc caacacacct
    23941 atgccaaaac cttgcaaacc aatgttaagg tgcaaaatta ccgtgctaaa gttcgtaact
    24001 acaagagtgc tcgtcatgca gccctcgcag cgaattttgt tccagaaagt gtttatgaca
    24061 atttggtagc agcagttcgc aagcatttgc cactcttaca tcgctatctt gagcttcgtt
    24121 caaaaatctt ggggatttca gatctcaaga tgtacgatgt ctacacaccg ctttcatctg
    24181 ttgaatacag ttttacctac caagaagcct tgaaaaaagc agaagatgct ttggcagtct
    24241 tgggtgagga ttacttgagc cgtgttaaac gtgccttcag cgagcgttgg attgatgttt
    24301 acgaaaatca aggcaagcgt tcaggtgcct actctggtgg ttcttacgat accaatgcct
    24361 ttatgcttct caactggcag gacaatctgg acaatctctt tactcttgtt catgaaacag
    24421 gtcatagtat gcattcaagc tatactcgtg aaactcagcc ttatgtttac ggagattact
    24481 ctatcttttt ggctgagatt gcctcaacta ccaatgaaaa tatcttgacg gagaaattat
    24541 tggaagaagt ggaagacgac gcaacacgct ttgctattct caataacttc ctagatggtt
    24601 tccgtggaac agttttccgc caaactcaat ttgctgagtt tgaacacgcc attcaccaag
    24661 cagatcaaaa tggggaggtc ttgacaagcg atttcctaaa taaactctac gcagacttga
    24721 accaagagta ttatggtttg agtaaggaag acaatcctga aatccaatac gagtgggctc
    24781 gcattccaca cttctactat aactactatg tatatcaata ttcaactggc tttgcggccg
    24841 cctcagcctt ggctgaaaaa attgtccatg gtagtcaaga agaccgtgac cgctatatcg
    24901 actacctcaa ggcaggtaag tcggactatc cacttaatgt catgagaaaa gctggtgttg
    24961 atatggagaa ggaagactac ctcaacgatg cctttgcagt ctttgaacgc cgtttaaatg
    25021 agtttgaagc ccttgttgaa aaattaggat tggcataaaa tggttgaatc gtatagtaag
    25081 aatgctaacc ataacatgcg tcgtcctgtc gtcaaagaag aaattgtaga cttgatgcgt
    25141 cagcgtcaaa agcaggtcac aggtttcttg aaagaattgg aaaactttgc ccgcaaggaa
    25201 aatattccta ttattcccca tgaaacggtt gcttatttcc gttttcttat ggaaaccatg
    25261 cagcctaaaa atattctgga aattgggacg gctatcggtt tttcagctct cttgatggct
    25321 gaacatgcgc caaatgctaa gattacaact attgatcgta atccagaaat gattggtttt
    25381 gccaaggaaa attttgccca gtttgacagt cgcaagcaaa tcactctcct agagggagat
    25441 gcggtggatg tcttatctac actgacagag tcttatgatt tcgtctttat ggattctgcc
    25501 aagtctaaat acatcgtctt tctgccagaa atcctcaaac atttggaagt tggtggtgtg
    25561 gttgtcttgg atgatatttt tcaaggtggt gatgttgcca aggatattat ggaagtccgt
    25621 cgtggtcagc gaaccattta tcgaggcctt caaaaattat ttgatgcaac cttagacaat
    25681 ccagaactca ccgcaacatt agtgccttta ggagatggta ttctcatgct tcgtaaaaat
    25741 gtagcagatg ttcaactgtc tgaaagcgaa tgattttcag aaaaatttaa gaaaaaatag
    25801 taaaatagat agagtaacac ttatctcaaa ggagtagaca tgaagaaaaa attattggca
    25861 ggtgccatca cactattatc agtagcaact ttagcagctt gttcgaaagg gtcagaaggg
    25921 gcagacctta tcagcatgaa aggggatgtc atcacagaac atcaatttta tgagcaagtg
    25981 aaaaacaacc cttcagccca acaagtcttg ttaaatatga ccatccaaaa agtttttaaa
    26041 aaacaatatg gctcagagct tgatgataaa gaggttgatg atactattgc cgaagaaaaa
    26101 aaacaatatg gcgaaaacta ccaacgtgtc ttgtcacaag caggtatgac tcttgaaaca
    26161 cgtaaagctc aaattcgtac aagtaaatta gttgagttgg cagttaagaa ggtagcagaa
    26221 gctgaattga cagatgaagc ctataagaaa gcctttgatg agtacactcc agatgtaacg
    26281 gctcaaatca tccgtcttaa taatgaagat aaggccaaag aagttctcga aaaagccaag
    26341 gcagaaggtg ctgattttgc tcaattagcc aaagataatt caactgatga aaaaacaaaa
    26401 gaaaatggtg gagaaattac ctttgattct gcttcaacag aagtacctga gcaagtcaaa
    26461 aaagccgctt tcgctttaga tgtggatggt gtttctgatg tgattacagc aactggcaca
    26521 caagcctaca gtagccaata ttacattgta aaactcacta agaaaacaga aaaatcatct
    26581 aatattgatg actacaaaga aaaattaaaa actgttatct tgactcaaaa acaaaatgat
    26641 tcaacatttg ttcaaagcat tatcggaaaa gaattgcaag cagccaatat caaggttaag
    26701 gaccaagcct tccaaaatat ctttacccaa tatatcggtg gtggagattc aagctcaagc
    26761 agtagtacat caaacgaata gtccaaatca atgagtcagg gaaaaaaact cgacttcagg
    26821 aaaaaatgaa gcaaacattc ccacaataaa acgcatagta caaggtttgt actgacccca
    26881 aaagttagac aattaattta tctgaaggat ttagttctgt attgcacagg gctaagtcct
    26941 tttagtttta ccttaattct cttattgttg taataatcaa tatagtctat aatggcttgt
    27001 tccaattgat taagtgattt aaatgttttc tcatagccat aaaacatttc ggattttaaa
    27061 atgccaaaga aagattccat cctaccgttg tcttggctgt ttcctttgcg tgacatagat
    27121 gcttgaattc ccttactctc taggaagcga tgataagaat cgtgttggta ttgccagcct
    27181 tggtcactat ggagaatcgt attctcgtag tgcttctctt tgaatgcctg ttccaacatt
    27241 aacgatcaat caatttaatc atgtacctaa tattagaatt gtttatccca aatttatttg
    27301 aaagcttctc taagctatat ccttgttttc taagttcata gatctgaact ttatcatcat
    27361 aagttaattt cataataaaa acaccccaaa agttagattt tttctgtcta acttttgggg
    27421 tgtagttcat gtacacctga tatgatgcgt tttataattt taaagacttt ttgaccagcc
    27481 tcattttttt aacttgatac tcagtgaaaa gcaaagatta aactaggaag ctagctgtag
    27541 gctgctcaaa gaacagcttt gaggttgcag ataaaacttg tgaggtcacc aacatatata
    27601 atgtgaagct gacgtggctt gaatagattt tagaagggta tgagtctgga agttttaatg
    27661 gataatgcaa gattccatag aatgggtaag ctagagttct tatgtgaaga gtttgggcat
    27721 aaacttttac cttttcctcc ctactcatct tagtatagaa aagtgaatct aaaatagtac
    27781 ataactgctt ctaaaacatt cttataaatt gatttaaatt ctcaaatcat attattcagt
    27841 tcttatttca ttttgctcta caatcctgtt gagaagacac gtgttcatat caaaaaggta
    27901 ttggcaagtt gcaatacctt tttacaaggt tcttttgtct tatttttgtt tcaactgact
    27961 atatctccta tggttctagt tcagaaggct aggctataat tatgattgat aagaagtatc
    28021 attccaagta ttgagagtga atgtttcaaa atcatgggtt tctataatgg tcaggctggc
    28081 atttgctaga ccgccatctt tacgaagaag tggttcttta tagcctagga gagtacgaag
    28141 actggcagta agattggcgc cgtgtccgac aattagaata cgctcagctg gactatcttt
    28201 taatgatttg ataaattgga tggtccgttg agttgtacta tagagggatt cggctccgaa
    28261 cattcgagtg tcaaattgag caagatttga acgaaaagcc tggatttgtt gcgggtaaat
    28321 agcttccaag gttgcaattt tcaaaccttc taacttccca agttgccatt cacggagatt
    28381 aggaacgatt tctaaagaac agggggtata gagttgactt tggataatct cagcagattt
    28441 gaccgctcga ggtaaatcac ttgaataaat ctgatcaaaa ggaatttcct tgagatactg
    28501 gccaagtcgt tttagggttt caatggattc aggaagaaga ggagaatcac cgctagcacc
    28561 ttgaaaacga ccttcttggt tccagagggt acgaccgtgg cggacaaagt agagtttcat
    28621 tacttgatgt cctccaaaat atctacaaag tctgccttta caaagctagc caagtcttgt
    28681 ggcgcgacga taatgctgtg tccgacttcg cctgcagaga caatcattcg atccaaatct
    28741 agagcaattt tatcgataaa aatgggataa ttgtgtttct gacgaattcc gacaggatta
    28801 ttggctccat gaatgtaacc agttgttttt tctaagtcct tttgtggaat catgctcact
    28861 tttttattgc cagaaatttt agctagtttc ttttcagaca agtgctgagt gatagggaca
    28921 attccgataa tcggtccggt cttgtctccc aaaagcgcca aggttttgaa aatctgatct
    28981 cgttcataac cttgaggaag ctctccttct agggcattga tttgaatccc ctgatgaggg
    29041 atagctgctt tagataggat ttgttccacc aatgtttttt tgattttaac tttttttgcc
    29101 attatttata tttatcctcc aattgactca tccaaatacc aagccagatt cccagcgcaa
    29161 agaagaaggc gatgatgaca taaccgacaa gtgaaagtcc tgtgtattgg atactttcag
    29221 cgtttcctgc atttggaatt aagatcaaaa gggtacttga taggacgata ccgatgatga
    29281 aatgatagac gcgtgagtgg tagttgttta aggcataatc catcaatttt gaaaaaacga
    29341 tgagagttgc acctgcacca attccaatcg gaaagaaggt tcccaagaga tcaaaagttt
    29401 taaaaccagt caacatagga gcatagagtc ccaaaatcaa aagtaagttc gatgggctga
    29461 ggccaggaac caagacgcca agggccaata gtgcgcctgc taggacgaag ttaagaaagc
    29521 tggcgcttaa ggttccaacg acaaaattta aggcatagag tcctaatcca gaaatgataa
    29581 aggttgtcca taaccaagct aaatcaatct tgtctcggtc agattctcga gttgattctt
    29641 tgaggaggct aggaactgta ccgataatag ctcccgcaaa gctccataat acaaagacct
    29701 gataattttc aagcaggtat tcaatcgggt aggaaaataa gccgattccc agaagcatac
    29761 cgatggcaac tggaataaag tacaaaacat tttctttaag gtctttaaag ggatgggcca
    29821 gaaagccaat cattcgttca tagattccta agattgctgc tagaacccct ccggaaattc
    29881 ccggtaggat aaatccaaga gcaattacaa tccctttaat aacgcgtgct aaccatgaga
    29941 gcatatattt cctccaacta tttctatttc aaaaaatcct tactatattg tatcacaatc
    30001 agacacaaaa agaaaaagca aatgataaac aaatgctttt aaggttttaa aaaaagtttt
    30061 cgaaaggttt cttctttatt ttttaaggga gagataacgt tgatatctaa atcgtggtca
    30121 aagccggcaa tttttccttt agatgtgtat tggtgaatat cataatctaa atcagtttta
    30181 ggactgctct ccaaaaatcc tgagtctgag ccgtaggacg gaatccaaac agaggtaaac
    30241 ttgcctgtat caatactgtg ttcttccatg aagtagacac caacgtagat gccgatgttt
    30301 ttagcaccta gtgatgctag ttttgctcga aagttttcga caccttcgtt catattagac
    30361 atggttttgt cttccacgtc aagccaatag taactagggc tgtaaggaga ggcagcattg
    30421 tagaaaactt cggcagcctt ttccatttct tggacacttt ttccagctac ataagcgtag
    30481 acagcaactg ggacattccg cttttgaagt tcagtgatat gactcttata ggccttgtct
    30541 attccattga taaatgaagc atcattttct tttgttgttt gagcaccact gtgaacacga
    30601 acaatagcac ctgaaatatt ttgtgagagg gcatcgtagt tgatttcctc aggacgctgc
    30661 cagccagaga ggtcaataat cggtttgtct aagtgtttca aagcctgtgc ttcaatctgt
    30721 gctatattgg attttgtttt aaacgattgg ctgtcattaa gtgggcgatt gatgattaaa
    30781 atgaacatca taatcccaaa aaaactaaat aaaataagtg gatgaatttg ttttctcata
    30841 tcttataagt ctaccctaaa aatcaaaaaa aatcaaaaaa atgggttaag gaagagactt
    30901 tagagcattt tttcattcaa gagtgcggaa tgatttgaaa tatggtataa taaaagggaa
    30961 tttctacaga aaagagaaga ttatgtcaaa ttttgccatt attttagcag cgggtaaagg
    31021 gactcgcatg aaatctgatt tgccaaaagt tttgcacaag gttgcgggta tttctatgtt
    31081 ggaacatgtt ttccgtagtg tgggagctat ccaacctgaa aagacagtaa cagttgtagg
    31141 acacaaggca gaattggttg aggaggtctt ggctggacag acagaatttg tgactcaatc
    31201 tgaacagttg ggaactggtc atgcagttat gatgacagaa cctatcttag aaggtttgtc
    31261 aggacacacc ttggtcattg caggagatac tcctttaatc actggtgaaa gcttgaaaaa
    31321 cttgattgat ttccatatca atcataaaaa tgtggccact atcttgactg ctgaaacgga
    31381 taatcctttt ggctatggac gaattgttcg taatgacaat gctgaggttc ttcgtattgt
    31441 tgagcagaag gatgctacag attttgaaaa gcaaatcaag gaaatcaaca ctggaacata
    31501 cgtctttgac aacgagcgtt tgtttgaggc tttgaaaaat atcaatacca ataacgctca
    31561 aggcgaatac tatattacag acgtcattgg tattttccgt gaaactggtg aaaaagttgg
    31621 cgcttatact ttgaaagatt ttgatgaaag tcttggggta aatgaccgtg tggcgcttgc
    31681 gacagctgag tcagttatgc gtcgtcgcat caatcataaa cacatggtca acggtgttag
    31741 ctttgtcaat ccagaagcaa cttatatcga tattgatgtt gagattgctc cggaagttca
    31801 aatcgaagcc aatgttacct tgaaagggca aacgaaaatt ggtgctgaga ctgttttgac
    31861 aaacggtact tatgtagtgg acagcactat cggagcagga gcggtcatta ccaattctat
    31921 gattgaggaa agtagtgttg cagacggtgt gacagtcggt ccttatgctc acattcgtcc
    31981 aaattcaagt ctgggtgccc aagttcatat tggtaacttt gttgaggtga aaggatcttc
    32041 aatcggtgag aataccaagg ctggtcattt gacttatatc ggaaactgtg aagtgggaag
    32101 caacgttaat ttcggtgctg gaactattac agtcaactat gacggcaaaa acaaatacaa
    32161 gacagtcatt ggagacaatg tctttgttgg ttcaaattca accattattg caccagtaga
    32221 acttggtgac aattccctcg ttggtgctgg ttcaactatt actaaagacg tgccagcaga
    32281 tgctattgct attggtcgcg gtcgtcagat caataaagac gaatatgcaa cacgtcttcc
    32341 tcatcatcct aagaaccagt aggagcctat catggagttt gaagaaaaaa cgcttagccg
    32401 aaaagaaatc tatcaaggac caatatttaa actggtccaa gatcaggttg aattaccaga
    32461 aggcaaggga actgcccgac gggatttgat tttccacaat ggggctgtct gtgttttagc
    32521 agtaacggat gaacaaaaac ttatcttggt caagcagtac cgcaaagcta tcgaggctgt
    32581 ctcttacgaa attccagccg gaaaattgga agtaggagaa aacacagccc ctgtggcagc
    32641 tgcccttcgt gaattagagg aagaaacagc ctatacaggg aaattagaac tcttgtacga
    32701 tttttattca gctattggct tttgtaatga gaagttaaaa ctatatttag caagcgattt
    32761 gacaaaagtg gaaaatccgc gtccgcagga tgaggatgaa accttggaag tccttgaagt
    32821 gagcttagaa gaagcgaaag aattaatcca atcaggtcat atctgtgatg ccaagacaat
    32881 tatggctgtt cagtattggg agttgcagaa aaaatagagg aggtcagtat gggtaaatct
    32941 ttattaacgg atgaaatgat tgaaagagct aatagaggcg aaaaaatttc aggtcctcct
    33001 ttgctagatg ataatgagga aactaagatt ttaccaacct cttcttcccg ttttggttat
    33061 gccaatccta aggatcatgg ttttagccag gaaaccttga agattcaggt cgaaccatct
    33121 attcataaaa gccgtcgtat tgaaaatacc aagagaaatg tcttcaattc taagttgaat
    33181 aaaatcttat ttgcggccat ctttctcttg attttgcttg ttttagcaat gaaacttttg
    33241 taatagaaaa ggaattgaaa tgaaaatagg aattattgct gctatgccag aagaactggc
    33301 ttatctggtc cagcatttag ataataccca ggagcaagtt gttttgggga atacctatca
    33361 tacaggaacc attgcttctc atgaagtcgt tcttgtagaa agtggaattg gtaaggtcat
    33421 gtctgctatg agtgtggcga ttttggctga tcatttccag gtggatgccc ttattaatac
    33481 gggttcagct ggggcagtag cagaaggtat cgctgttggg gatgtcgtga ttgctgacaa
    33541 attagcctat catgacgtgg atgtcacagc ttttggctat gcttatggac aaatggcgca
    33601 acaaccgctt tatttcgaat cagacaaaac ctttgttgct caaatccaag agagtttatc
    33661 tcaattggac caaaactggc atcttggttt gattgctaca ggagatagtt ttgttgcagg
    33721 aaatgacaag atagaagcga ttaagtccca tttcccagaa gttttagccg tggagatgga
    33781 gggggcagct attgctcaag cagcgcatgc cctcaatctc ccagtcttag tcatcagagc
    33841 tatgagtgac aatgccaacc atgaagcaaa catctttttt gatgagttta ttatcgaagc
    33901 tggacgtcgc tctgcccaag tcttgttgac ctttttgaag gctttagatt aagcggaaat
    33961 ttgacagttt ttctagctta tgataagatt taagtaaaga aaagctagaa aacgtttcag
    34021 aggatattat gagtattgaa atgaccgtca gtgagattgc agaggtctta ggattatctc
    34081 gccaagcaat caataaccgt gtcaaagaat taccagaaga agacacagat aaaaatgaca
    34141 aaggggtaac agttgttacc agaagtggct tgattaagct agaagaaatc tataaaaaaa
    34201 cgatttttga agatgagcct gtcagtgaag atgtcaaaca acgtgaactg atggagattc
    34261 tagtggatga gaagaatgca gaaattcttc gtctttatga acaattaaaa gccaaggatc
    34321 gtcagttatc agaaaaagac gagcagatgc gtatcaaaga ccgtcagatt gctgagaaag
    34381 acaaacaatt agatcagcaa caacaattga cccttcaagc catgaaggat caagaaaatc
    34441 ttaagctaga gctggaccaa gcaaaagaag aagtccaatc cactaagaaa ggcttttttg
    34501 ctcgtttatt tggaggataa tcaaggagct gtttaggtta aatgctaacc tgatggcttc
    34561 ttttgtttgt gaatagtata gttgattaga acagagacag tagaggagag gtacagaatg
    34621 gaacgattag aagattacat tgcttttgac ttagaattta atcagcacga aggacaaaca
    34681 cacttgattc aagtatcggc agtgcgtttt agagatggtc gggaaatcga tgcctatgat
    34741 tcctatgttc ataccagcgt ccctctaaaa agctttatca atggtttgac cgggattaca
    34801 gctgagacct taaaagatgc tcctccagtt gagaaagtct tagaagaatt ccaagagttt
    34861 gtgggttctt tgctgatgat aggctacaat gctgctaaaa gtgatttacc tattttagca
    34921 gatcatggtt tagactatag ccaacagtac aaggtggatt tgtatgatga agcttttgaa
    34981 cgtcggagtt cagatttaca tggtattgcc aatctcaaat tgcaaactgt tgcctcattt
    35041 cttggatttc aaggtcagtc tcataatagt ttagaggatg ctcggatgac ggcgcgtgtt
    35101 tacgaatcct tcttagagtc ggatcaagct agggaattgt tagagacaga aagtagctta
    35161 tcaaacaatc cttttggtgt cttggacttg tctcaattat ttgactagga gtgcctatga
    35221 aacctgaaaa acctaaaaaa ttgggtctta aacagattta cctcaatctt gataaaatcc
    35281 tctttctatt tttcttgatt tttatgatag tggagtattt gtgggtacca ttcaattcat
    35341 ggttggctag cttcttatta gatcagacag gttatctttt tatttcctat aacaatgtct
    35401 tagccatcct tactcattct ccattgatta gtctagcttt tttagccttg attgtaatta
    35461 accttctggt tgcttatttt caaataggac tcctctttat tggtgctcgt catctcctct
    35521 ataatgaaaa gcgaaggcta attgagtata tccgcaaggt tttccatgaa agttttggat
    35581 ttatgaaaaa gctaacttgc gctaaagcct tgtttatctt tttctatata gctatgcttt
    35641 ttccttttat acggaaaatg ctgaagattt attatcttaa taaaatcgtc attccagagt
    35701 ttatccaagc ttatttagaa gataaatatt ggatgtggtg gctgagcatc ctacttctat
    35761 ctcttatctt tctctatgtc tctgtcagat tgatgtttgc ccttccgaag attgtatatg
    35821 atcagctgac tgttcgagaa gcagtgatgt ttagcttgga gaaaaccaag aagagagtta
    35881 ctttttatgc ttggaattta ttttacatct tgctcaaagc acatttatta ttttatcttc
    35941 ctttgattcc tttattattg gctcaaactt tggtagatga tatcactcag agagagtctc
    36001 tgattcttgg tattttgaat tttgtcgtga ttaaaaatct ctattatatg gctctgactt
    36061 attttttggt taaatttgtt tcatttttga caggaaagga gctggatatg cttcctagga
    36121 gagaaaaaga tcacatcgtg cgatggggtg tcatgacttg tgccagtctt ttctttgcct
    36181 tagaaggtta tatttatctg gaggctccca tggttcatct acctcaactt atttctcacc
    36241 gaggggtttc caatgcaaat gggattcaaa atacagtaga gtccttggaa actacagcac
    36301 aactcaaacc agacttggtg gagacggacg tgcaggaaac aaaagatggg cagtttgtca
    36361 tgatgcatga tgctaacttg aaaaatctag caggtatcaa taaaagtcct caagacttaa
    36421 acttggagga gcttaaaggg attgatattt ttgaaaatgg ctaccagact aaaatttcaa
    36481 gctttgaaga ttatctcagt cgagccaacg aacttggtca aaaattacta attgaaatta
    36541 aaaccagtaa aaaagatagt ccagacatga tgaaccgctt tttagcccgt tatgctgcaa
    36601 agctcaagat ttatggacat caaatccagt ctttagacta ccatgttgtc gaaaaagtaa
    36661 gacagtatga tgccgaactg ccagtttatt tcatcatgcc ctacaattct gtctttccta
    36721 aaacaagagc gacaggatat actatggagt actcaacctt ggatgaatat tttgtaagca
    36781 aactatggac aacggatcag aaactttatg tctggactgt caatgattca gaagctatca
    36841 gcaaatctct tcacttagga gtagatggag tgattacaga tgatttggaa aaagttcagc
    36901 gggaaataga agtagcccaa gaagatccag aatatacgga tttgctcttg aaaaaagcat
    36961 tggaattctt tgaattttag taataaaaaa gaggaacggt tgttcctccc atgataggta
    37021 agtattcttg tgaatgcttg cttttttgtg gttgcaatcc gtttacgaga attgtttgta
    37081 ttgttcttgt ttcaatttac tttatagtgc tttgaagttg gaatgctaca ctataacttc
    37141 taaaatatag taaaatgaac caaaaatagt acacaatgtg gtataatctt cttatggcat
    37201 attcaataga ttttcgtaaa aaagttctct cttattgtga gcgaacaggt agtataacag
    37261 aagcatcata cgttttccaa atctcacgta atactattta tggctggtta aagctaaaag
    37321 agaaaacagg agagctaaa
//
LOCUS       DAVKMJ010000022        36020 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000022 DAVKMJ010000000
VERSION     DAVKMJ010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 36020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36020
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.022"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            100..597
                     /locus_tag="VW348_001134"
     CDS             100..597
                     /locus_tag="VW348_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEU9746039.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            597..2252
                     /gene="dnaX"
                     /locus_tag="VW348_001135"
     CDS             597..2252
                     /gene="dnaX"
                     /locus_tag="VW348_001135"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEU9746040.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATDKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            2280..2474
                     /locus_tag="VW348_001136"
     CDS             2280..2474
                     /locus_tag="VW348_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEU9746041.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            2624..3394
                     /gene="sufC"
                     /locus_tag="VW348_001137"
     CDS             2624..3394
                     /gene="sufC"
                     /locus_tag="VW348_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEU9746042.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            3422..4684
                     /gene="sufD"
                     /locus_tag="VW348_001138"
     CDS             3422..4684
                     /gene="sufD"
                     /locus_tag="VW348_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEU9746043.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            4695..5921
                     /locus_tag="VW348_001139"
     CDS             4695..5921
                     /locus_tag="VW348_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU9746044.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATAFYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVINPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            5908..6348
                     /locus_tag="VW348_001140"
     CDS             5908..6348
                     /locus_tag="VW348_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEU9746045.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            6402..7814
                     /gene="sufB"
                     /locus_tag="VW348_001141"
     CDS             6402..7814
                     /gene="sufB"
                     /locus_tag="VW348_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEU9746046.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(8045..9286)
                     /locus_tag="VW348_001142"
     CDS             complement(8045..9286)
                     /locus_tag="VW348_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEU9746047.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKTPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            9389..10498
                     /locus_tag="VW348_001143"
     CDS             9389..10498
                     /locus_tag="VW348_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEU9746048.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            11032..11379
                     /gene="ssrA"
                     /locus_tag="VW348_001144"
     tmRNA           11032..11379
                     /gene="ssrA"
                     /locus_tag="VW348_001144"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(11552..11639)
                     /locus_tag="VW348_001145"
     tRNA            complement(11552..11639)
                     /locus_tag="VW348_001145"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11603..11605),aa:Ser,seq:gga)
     gene            11802..12542
                     /locus_tag="VW348_001146"
     CDS             11802..12542
                     /locus_tag="VW348_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9746049.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            12539..13450
                     /gene="pfkB"
                     /locus_tag="VW348_001147"
     CDS             12539..13450
                     /gene="pfkB"
                     /locus_tag="VW348_001147"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEU9746050.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTVEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            13447..15399
                     /locus_tag="VW348_001148"
     CDS             13447..15399
                     /locus_tag="VW348_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9746051.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSAGQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            15563..17788
                     /locus_tag="VW348_001149"
     CDS             15563..17788
                     /locus_tag="VW348_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEU9746052.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKTLLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKAQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(17833..18261)
                     /locus_tag="VW348_001150"
     CDS             complement(17833..18261)
                     /locus_tag="VW348_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746053.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITAGITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            18399..19541
                     /locus_tag="VW348_001151"
     CDS             18399..19541
                     /locus_tag="VW348_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEU9746054.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSVQPIEAI
                     SKLLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            19550..20764
                     /gene="thiI"
                     /locus_tag="VW348_001152"
     CDS             19550..20764
                     /gene="thiI"
                     /locus_tag="VW348_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEU9746055.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGRAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            20899..21722
                     /locus_tag="VW348_001153"
                     /pseudo
     CDS             20899..21722
                     /locus_tag="VW348_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            21744..22483
                     /locus_tag="VW348_001154"
                     /pseudo
     CDS             21744..22483
                     /locus_tag="VW348_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            22496..23662
                     /locus_tag="VW348_001155"
     CDS             22496..23662
                     /locus_tag="VW348_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU9746056.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     ATTFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            24170..25663
                     /locus_tag="VW348_001156"
     CDS             24170..25663
                     /locus_tag="VW348_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU9746057.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            25676..26740
                     /locus_tag="VW348_001157"
     CDS             25676..26740
                     /locus_tag="VW348_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9746058.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLRDHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     FQLDELNLLVKSRFNEMFGDPLNNNKKFAVKTGQQCFKFSSGKFLDKHDRVFEGYPAY
                     GGNGIAWKSRKYLIDNPTIIIGRVGAYCGNVRTTHGKVWISDNAIYIKEFKNSDFNLV
                     FLLELMKVIDFSKFADFSGQPKITQKPLENQKYILPPLALQNEFADFVALVDKSQLAI
                     QKSLEELETLKKSLMQEYFG"
     gene            26800..27036
                     /locus_tag="VW348_001158"
     CDS             26800..27036
                     /locus_tag="VW348_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEU9746059.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            27033..27446
                     /locus_tag="VW348_001159"
     CDS             27033..27446
                     /locus_tag="VW348_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEU9746060.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            27564..28529
                     /locus_tag="VW348_001160"
     CDS             27564..28529
                     /locus_tag="VW348_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEU9746061.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            28553..29136
                     /locus_tag="VW348_001161"
                     /pseudo
     CDS             28553..29136
                     /locus_tag="VW348_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466650.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
     gene            29166..32516
                     /locus_tag="VW348_001162"
     CDS             29166..32516
                     /locus_tag="VW348_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU9746062.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFGENCCVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIEEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            32787..32864
                     /locus_tag="VW348_001163"
                     /pseudo
     CDS             32787..32864
                     /locus_tag="VW348_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(33102..33572)
                     /locus_tag="VW348_001164"
     CDS             complement(33102..33572)
                     /locus_tag="VW348_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU9746063.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(33589..35862)
                     /locus_tag="VW348_001165"
     CDS             complement(33589..35862)
                     /locus_tag="VW348_001165"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEU9746064.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHINKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
BASE COUNT        11011 a         6436 c         7811 g        10762 t
ORIGIN      
        1 ggggttaccc actacaaata ttatagagcc caaaatcctt tgtttactaa acaagggatt
       61 tttcttttgt ctctgctcct tttttgatat aatagttcta tgttaaaatc agaaaaacaa
      121 tcacgttatc aaatgttaaa tgaagaattg tccttcctat tggaaggcga aaccaatgtt
      181 ttggctaatc tttccaacgc cagtgctctc ataaaatcac gttttcctaa taccgtattt
      241 gcaggctttt atttgttcga tggaaaggaa ttggttttag gccccttcca aggaggtgtt
      301 tcctgcatcc gtattgcact aggcaagggt gtttgtggtg aggcagctca ctttcaggaa
      361 actgttattg ttggagatgt gacgacctat ctcaactata tttcttgtga tagtctagct
      421 aaaagtgaaa ttgtggtgcc gatgatgaag aatggtcagt tacttggagt tctggatctg
      481 gattcttcag agattgagga ttacgatgct atggatcgag attatttgga acaatttgtc
      541 gctattttgc ttgaaaagac aacatgggac tttacgatgt ttgaggaaaa atcttaatgt
      601 atcaagcact ttatcgaaaa tatagaagtc aaaacttctc ccagttagtt ggtcaagaag
      661 ttgtggctaa gactcttaaa caagcggtgg agcaagagaa aataagtcac gcttatcttt
      721 tttctggtcc tcgtggaacg ggaaaaacca gtgttgctaa aatctttgcc aaggctatga
      781 actgtcccaa tcaagtgggt ggcgaacctt gcaataactg ctatatttgt caagcagtga
      841 cggacggtag tttagaagat gtcattgaaa tggatgcagc ttctaataat ggggtagatg
      901 aaattcgcga aattcgtgat aaatctacct atgcgcctag ccttgctcgt tataaggttt
      961 atatcataga tgaggttcac atgctgtcta caggggcttt taatgccctc ctaaagacgc
     1021 tggaagaacc aacacagaat gtagtcttta ttttggccac tactgaattg cacaagattc
     1081 ctgctactat tctatcccgt gtgcaacgtt ttgagtttaa atcaattaag acacaggata
     1141 ttaaggaaca tattcactat atcttagaaa aagaaaatat cagttctgaa ccagaggctg
     1201 tggaaatcat tgccagacgg gcggaaggtg gaatgcggga cgccttgtct attttggatc
     1261 aagccctgag tttgacacag ggaaatgagc tgacgactgc tatctctgaa gaaattactg
     1321 gcaccattag cctatcagcc ttggatgatt atgtggcggc cttgtctcaa caggatgttc
     1381 ccaaagcttt gtcttgcttg aatcttcttt ttgacaatgg taagagcatg actcgttttg
     1441 tgaccgatct tttgcactat ttaagagact tgttaattgt tcaaacaggg ggagaaaata
     1501 ctcatcatag ttcagtcttt gtagaaaatt tggcacttcc tcaaaaaaat ctgtttgaaa
     1561 tgattcgctt agcaacagtg agtttagcag atattaagtc tagtttgcag cccaagattt
     1621 atgctgaaat gatgaccgtc cgtttggcgg aaatcaagcc cgaaccagct ctatcaggag
     1681 cggttgaaaa tgaaattgct acgctgagac aggaagttgc ccgtctcaaa caagagcttt
     1741 ctaatgtagg tgcggttcct aaacaagttg caccagctcc tagtcgacca gctacggaca
     1801 aaacagtcta tcgtgtcgat cgcaataaag tgcaatctat cttacaagag gccgtcgaaa
     1861 atcctgattt agcacgtcaa aatctaattc gtttgcagaa tgcctgggga gaggtaattg
     1921 aaagtctagg tgggccggac aaggctctgc tagttggttc tcaaccggtt gctgccaatg
     1981 aacaccatgc tattcttgct tttgagtcta acttcaatgc tggtcaaact atgaaacgag
     2041 acaatctcaa taccatgttt ggtaatatcc tcagtcaggc ggcaggtttt tcacctgaga
     2101 ttttagctat ttccatggag gaatggaaag aagttcgcgc agccttttca gccaaagcca
     2161 aatcttctca aactgaaaaa gaagtagaag aaagcctgat tccagaagga tttgaatttt
     2221 tggctgataa agtgaaggta gaggaagact aaagaaagat ttcatgatac aataagttta
     2281 tgaataaaca acaatttatt attatggcgc tgtttacagc tgctgagacc tattttttca
     2341 atgaagcctg gatgactggc cgctatatta tggcagcctt ttgggcaatt ttactcttta
     2401 gaaatttccg agtcagttat gtgatgggca aaatcgttga tgtcatcgat cagcatttta
     2461 ataggaaaga ctagccctca gcttccagac aaaatcaaag ccttttaggc ttttttttgt
     2521 tatactagaa aagtatattt atagaatttt tgctctattt ctggggaaat cagacgtttt
     2581 tctagtaagt actgtaaaag ttttgaaaaa gaaaggaact atcatgtcag tattagagat
     2641 taaagatctt cacgttgaga ttgaaggaaa agaaatttta aaaggggtta acctgaccct
     2701 gaaaacagga gaaattgccg ctatcatggg accaaatggt acaggtaaat cgactctttc
     2761 tgccgctatc atgggaaatc caaactatga agtaactaaa ggtgaagttt tgtttgatgg
     2821 cgtaaacatc cttgagttgg aagtggatga gcgtgcgcgt atgggacttt tccttgctat
     2881 gcaataccca tcagaaatcc ctggaattac caatgctgag tttcttcgtg ccgctatgaa
     2941 tgcgggtaaa gaagatgatg agaagatttc agttcgtgag tttattacta agctagatga
     3001 aaaaatggaa ttgctcaaca tgaaagaaga aatggcagag cgttacctca acgaaggctt
     3061 ctctggtggt gagaaaaaac gcaatgaaat tcttcaactt ttgatgttgg agccaacatt
     3121 tgctcttttg gacgagattg actcaggtct tgatattgac gctcttaaag ttgtgtctaa
     3181 aggtgtcaat gccatgcgtg gtgaaggttt tggtgctatg atcatcactc actaccaacg
     3241 tcttttgaac tatatcacac ctgatgtggt acacgtgatg atggaaggtc gtgttgtcct
     3301 ttctggtggt ccagaattgg ctgcgcgttt ggaacgtgaa ggatacgcaa aattagctga
     3361 agaacttggc tacgactaca aggaagaatt gtaatttcct cgtatctttt aggagaagta
     3421 aatgactaga gaaaatatta aacttttttc agaaatgcac gctgaaccaa gctggttggc
     3481 tgatctccgt caaaaagctt ttgacaagat tgagactttg gaattaccag ttattgagcg
     3541 tgtcaaattc caccgttgga atctgggtga tggaacgatt acagaaaatg agccatcagc
     3601 aaatgttcca gatttcacag ctttagatca tcacttgaag ttggtgcaag taggaactca
     3661 aactgttttc gaacaaactc cagttgagtt agctgaacag ggtgttgtct tcacagactt
     3721 tcactcagct ttagaagaaa ttccagagct gatcgaagaa ttcttcatgt catctgttaa
     3781 gtatgatgat gacaagttgg cggcttacca cacagcttac tttaacagtg gtgctgtact
     3841 ctatattcca gataacgtag aaatcacaga gccaattgaa ggaattttct accaagatag
     3901 cgatagcaat gtgccgttta acaagcatat tatgattatc gctggtaaaa attctaagat
     3961 tagttatctg gagcgtttag agtcacgcgg tgaaggaagt gacaaagtaa ctgccaatat
     4021 cacagtggaa gtgattgcac gttctggtgc gcaagtcaag tttgctgcta tcgaccgtct
     4081 aggtgaaaac gtcactgcct acattagccg tcgtggtaaa ttaggcaacg atgcaagtat
     4141 tgactgggct atcggtgtca tgaacgaagg aaatgtcgtt gctgattttg atagtgactt
     4201 gattggtaat ggtagccatg ctgacctcaa ggttgtagct ctttcaagtg gtcgtcaggt
     4261 acaagggatt gatactcgtg taactaacta tggctgcaac tctatcggaa atatcctaca
     4321 acatggggtt atccttgaaa aagcaacttt gactttcaat ggtatcggcc acatcatcaa
     4381 gggtgctaag ggagcagatg cgcaacaaga gagccgtgtt ctcatgcttt cagaccaagc
     4441 gcgttcagat gctaacccaa ttcttttgat tgatgaaaat gatgtcactg caggacacgc
     4501 agcgtctatc ggacaagttg atccagaaga catgtattac ctcatgagtc gtggattgga
     4561 taaggcaact gcagagcgtt tggttgttcg tggtttcctt ggatctgtta tcgtggagat
     4621 tccagtcaag gaagttcgtg atgaaatgat tgcaactatc gaagagaaat tgtcaaaacg
     4681 ctaaggggaa gcctatgtta gatgtagaag cgattcgcaa ggattttcca attttagatc
     4741 agattgtcaa tgatgaacct ctggtctatc tggacaatgc tgcgacgaca caaaaacccc
     4801 tagtagttct gaaagctatt aacagttact atgagcagga caatgccaat gttcaccgtg
     4861 gtgtccatac cttagcggaa cgagcgacag ctttttatga agctgctcgt gaaaccattc
     4921 gtaagtttat taatgcaggc tctacaaagg aagttctctt taccagagga acgacaacca
     4981 gccttaactg ggtggcacgc tttgctgagg aaattctcac tgagggagac caggtcttga
     5041 tttcagtaat ggaacaccat tctaatatca ttccatggca ggaagcttgt cgaaagactg
     5101 gagcagagct tgtctatgtc tatcttaaag acggtgcctt ggatatggag gatttgcgag
     5161 ctaaattgac tgataaggtt aaatttgttt ccctagctca tgcctccaat gttcttggtg
     5221 tgatcaatcc gatcaaggaa atcactcaat tagcccacca agttggggca atcatggtag
     5281 tggatggtgc tcaatctaca cctcatatga agattgatgt ccaggacttg gatctggact
     5341 ttttcgcctt ttcgggtcac aagatggctg gtccgactgg tatcggtgtc ctttacggca
     5401 aagaaaagta tcttgagcaa atgtctccag tagaatttgg cggcgagatg attgattttg
     5461 tctacgagca atttgctagt tggaaggaat tgccttggaa atttgaggct ggaacgccaa
     5521 atatggcagg agctattgga cttgcgactg cagttgatta tttggaaaag attggtatgg
     5581 atgccgttga agctcatgaa caggaattga ttgcgtacgt ctatccaaaa ctgcaggcaa
     5641 ttgagggatt gaccatttac ggttctcagg atttggctca acgttcgggt gttattgcct
     5701 ttaacctagg tgatctccat cctcacgatc ttgcgacggc tctggattat gaaggagtgg
     5761 ctgttcgtgc tggtcaccat tgtgcgcaac ccttgcttca gtatttggaa gtcccagcaa
     5821 cagctcgtgc aagtttttat atctacaata ccaaggcaga ttgcgacaaa ctagtcgatg
     5881 ccctacaaaa gacaaaggag tttttcaatg gcactttcta aactagatag cctttatatg
     5941 gcagtggtag cagaccattc gaaaaatcca catcaccaag ggaagttaga agatgctgag
     6001 caaatcagtc tcaacaatcc gacttgtggg gatgtcatca acctctctgt caagtttgat
     6061 gcagaggacc gtttggaaga tattgctttt ctaaattcag gatgcacgat ttcaactgct
     6121 tctgctagta tgatgacaga tgccgtttta ggaaaaacca aacaagaaat tttagaactg
     6181 gcgactattt tttctgaaat ggttcaaggg caaaaagatg agcgtcaagg ccaacttgga
     6241 gacgcggcat tcttgtcagg tgttgccaaa ttccctcaaa gaatcaagtg tgcaacccta
     6301 gcttggaatg cccttaagaa aacaattgaa aatcaagaaa aacagtaaga caagtttctt
     6361 ttgtcttatg aattattaga aatgaagaaa gaaaggatac tatggctgaa gaaagagtag
     6421 aaccaaaacc aattgacctt ggtgaatata aatttggttt ccatgacgat gtagagcctg
     6481 tcttatcgac aggaaaagga ctcaacgaag gtgttattcg tgaattatct gctgctaagg
     6541 gtgagcctga gtggatgttg gagttccgtt tgaagtctta tgaaaccttc aaaaaaatgc
     6601 ccatgcaaac ttggggagca gacttgtcag agattgactt tgatgactta atctactacc
     6661 aaaaaccatc tgacaaacca gcccgttctt gggatgatgt acctgaaaag attaaagaaa
     6721 cctttgaacg tatcgggatt ccagaagctg aacgtgctta tttagcaggg gcttctgccc
     6781 agtacgagtc agaagtggtt taccacaaca tgaaggaaga gttccaaaaa ttaggtatta
     6841 tctttacaga tacagattcc gcactcaagg aatacccaga cttatttaaa caatactttg
     6901 cgaagttggt accgccgaca gataacaagt tggcagccct caactcagca gtatggtcgg
     6961 gtggaacttt tatctacgtg ccaaaaggtg tcaaggtaga tattccactt caaacttatt
     7021 tccgtatcaa taacgaaaat ataggtcagt tcgaacgtac cttgattatc gttgatgagg
     7081 gagcaagcgt ccactacgta gaaggatgta cagcaccaac atattcaagc aatagcttac
     7141 acgctgccat tgtagaaatt tttgctttgg acggagctta tatgcgttat acaactatcc
     7201 aaaactggtc tgataacgtc tataacttgg taacaaagcg tgctaaggct caaaaggatg
     7261 ccactgttga gtggattgat ggaaacttgg gtgccaaaac gactatgaaa tatccatctg
     7321 tttaccttga tggagaagga gcgcgtggta ccatgctctc tatcgccttt gctaatgcag
     7381 ggcaacacca agacacgggt gctaagatga ttcacaatgc tccacatacc agctcgtcta
     7441 ttgtgtctaa atccatcgct aaaggtggag gaaaggttga ctaccgtgga caagtcacct
     7501 ttaacaagaa ctctaagaaa tctgtttccc acattgaatg tgataccatt atcatggatg
     7561 acttgtcagc atcagatact attccattta atgaaattca caactcgcaa gtggctttgg
     7621 aacacgaagc caaagtatct aagatttcag aagagcaatt gtattatctc atgagccgtg
     7681 gattgtcaga atctgaggca actgaaatga ttgtcatggg atttgtagaa ccctttacaa
     7741 aagaacttcc aatggaatac gcagttgagc tgaaccgctt gattagctat gaaatggagg
     7801 gatcagttgg ataaaatttg attttatact cttcgaaaat ctcttcaaac cacgtcagca
     7861 tcgccttacc gtatgtatgg ttactgactt cgtcagtttc atctacaacc tcaaaacagt
     7921 gttttgagca agctgcggct agcttcctag tttgttcttt gattttgagt attagattta
     7981 ctcaaaatca aggattttga agatgaactt gtatcaaaaa atcgcggttt aaaatcgcga
     8041 ttttttataa tttctcgtta acaaagcgga caaactgatt ccaccaaact tttaagaaga
     8101 aggctttttc aattttcttg tctgctacca tttcgaaact agggcgctct gtggtgatgt
     8161 aaccttgacc aatcaagtcc ttgtcttcat aagtcaaatg gccaaccact gttccagctt
     8221 caagtggtgc tgggattgct ttggaatcag gtgtgaattg aacagattgg gaagattgat
     8281 tcccaacacg ttcgattaga tagatatcct ctggagccac tgcagttact gtatcttctt
     8341 ttccatcttg tacaggggtt ttgctatctt gataggcatc gccttgttga acgattttgc
     8401 gaagtgtaaa tgtagaagaa atataatcca ttagggaaga tgtagctgta aatcgagcgt
     8461 aaggattatt gtcttgatga tctgcattta aaacaactgt gatgactctc atgccttttt
     8521 cgacagtagt accaacaaaa gactctccag ccttatctgt tgttcctgtt tttagcccat
     8581 caaaaccacc acggtaagca ggcatacctt ctaacatgta gttggttgaa gtgattgtca
     8641 tcccagcaaa agtagaagaa ggttttttgg tgatttctaa gacttgtggg tattttttga
     8701 tgaggttgcg agcaacgata gcgacatcat aagcactaag cttattttcc tcatcttttt
     8761 tagaacctgg gtaaatgtta tcccctagag tttcattgtt aagacctgtc gtattgacaa
     8821 cagtggcatc ctgaattccc cattccaaga gttttgcccg catcatatcg acgaaatctt
     8881 tttctgagcc agcaattttc tcagctaggg caatagcggc gctgttggca ctagatacca
     8941 gagttgcttc aagcaactct tcgacagtat aattacgggc ctccatagga atattactgg
     9001 cttcagaatt tgtcgtcaat tgataaggat aatcagaaat atctacagga gtggagaggg
     9061 taatacttcc gttttccaaa gcttcataga ccagataaac agtaatcaat tttgttatgg
     9121 aagcaatttc gacaggttgc gttgcatcct tctcatagag aattttacca gtatttgcct
     9181 caacagcaat cgcatgttta gcggcaatgg taaaatcttg agcaacagca gtagaagcac
     9241 cccctaaaag agagacagtt aacaaagtta aaaatatttt tttcatagta gtcttattct
     9301 atcataaaga aaaaaaatat tcttgcttta ataattcatc tgttaagctt tttgaaaata
     9361 tggtaaaata aagtgaggga ggtaactcat gtttcgtaga aataaattat ttttttggac
     9421 cacagaaatt ttactcttaa ccatcatctt ttacctatgg agacagatgg gatctttgat
     9481 taaccctttt gttagcgtgc ttaatacaat tatgattcca tttttattag ggggctttct
     9541 ttattatttg acaaacccta ttgttacttt cttaaataaa gtctgtaaac tcaatcgttt
     9601 gcttggtatt ttaattacct tgtgtacttt ggtctgggga atggtcatag gtgttgtcta
     9661 tctcttacct attttgatta atcagttatc tagtttgatt atatctagtc aaactattta
     9721 tagtcgagta caagacttaa tcatagactt atctaattat cctgcgctcc agaatttgga
     9781 tgtagaagct acaattcagc agttaaactt atcctatgtt gatattcttc aaaatatcct
     9841 aaatagcgta tcaaatagtg tggggagcgt cttgtcagct cttatcagta ctgttttgat
     9901 tttgattatg actccagttt ttttggttta tttcttatta gatggacata aattcttgcc
     9961 catgcttgaa agaacgattc taaagaggga tcgcttgcat attgcaggct tattaaagaa
    10021 tttaaatgcg acgattgctc gctatattag tggagtttcg attgacgcaa tcattatagg
    10081 ttgtttggct tatattggct atagtattat tggtttaaaa tatgctttag tttttgccat
    10141 tttttctggt gtagccaatt taattcctta tgtggggcca agtattggtt tgattcctat
    10201 gatcatcgca aatatattca ctgatcccca tagactgctg attgcagtga tttatatgct
    10261 tgttgttcag caggtagatg gcaatatctt atatcctcga atcgtaggaa gtgttatgaa
    10321 ggttcatcca atcacgattt tagttttact tttgttgtca agcaatatct atggtgtagt
    10381 tggaatgatt gtcgcagtgc caacctattc tatcttgaaa gaaatttcta agttcttatc
    10441 ccgtttgtat gaaaatcata aaataatgaa agaacgagaa agagaattag ctaagtaaaa
    10501 gtcaggagaa ccctgatttt tctttactgg aagtggcctt tagattagaa gactgaaaat
    10561 aagttaaagt cttaaactaa ttttcacagc taagaatagt agaagttaat ctgataaaaa
    10621 tcgaaaaaac cagtggaatt ctgtgtcagg gtaagttcca ctggttttca tagtctatta
    10681 aagttcgaat gaaacctatt tatagtagat tgaaactaga atagtacacc tctaattcta
    10741 aaacattgtt agaaatcgat ttgactgtcc tgatctattc gtcctattct tatttcattt
    10801 tactatattt tggtgcaata agtgaaaagt agaccgaata atataaggat tgattttata
    10861 gtttttaaac tcaaatgaat tgaaataaag agagtacgaa aattctcatc tgaaagtatt
    10921 ttagaataat tctcttcgtg aatttcttca aaacagatag cttcatctta ggtatgtgat
    10981 ttctttttgc atttttgagt tagataaggt ataatggttt tattgtcttt tggggtcgtt
    11041 acggattcga caggcattat gaggcatatt ttgcgactcg tgtggcgacg taaacgctca
    11101 gttaaatata actgcaaaaa ataacacttc ttacgctcta gctgcctaaa aaccagcagg
    11161 cgtgacccga tttggattgc tcgtgttcaa tgacaggtct tattattagc gagatacgat
    11221 taagccttgt ctagcggttt gataagagat tgatagactc gcagtttcta gacttgagtt
    11281 atgtgtcgag gggctgttaa aataatacat aacctatggt tgtagacaaa tatgttggca
    11341 ggtgtttgga cgtgggttcg actcccaccg gctccattat tcctttgcat tccttggtaa
    11401 aacgttgtta aatcaacgtt ttttattttt atctttggta ttcctttgca ttcttttgct
    11461 aaaaagggag tcacaaacag accctatttt aaaaaaagga tagaaaaaag gatacaacat
    11521 ttgtcgcatc ctaaaaataa tcttttttcg acggaagaca tgggattcga acccacgcac
    11581 gctattacac gcctaccgcg tttccaacac ggcctcttaa gcctcttgag taatcttcca
    11641 atacttactc aaatagtcta ccataaaggc tcttatcttg caataaaaat tctagaaata
    11701 agaaaaaatg atagattttg aaagaaaatg ataaaaaatg cttgacttcg aaagaaagta
    11761 tgatagaatg aatagtgtaa acgataacag gaggtgattc agtgttaaaa acagaacgta
    11821 aacaactaat tttagaggag ttaaatcagc atcatgtagt ttctctagaa aaattagtta
    11881 gtttgctaga aacgtcagaa tcaacggttc gaagagactt ggatgagttg gaagcggaaa
    11941 acaagcttcg tcgtgtgcat ggtggagcag aactccccca ctccttacag gaagaagaaa
    12001 ccattcaaga aaaatctgtc aaaaaccttc aagaaaagaa gttgctggct cagaaagcag
    12061 cctctctcat taaagaaaaa gatgtcatct ttatcgatgc tggaacaaca actgcttttt
    12121 tgattcatga attggtcaat aagaatgtta cagttgtgac caactccatt caccatgccg
    12181 ctcagttggt tgaaaagcag attccaactg tcatggttgg aggaaacgtc aagacggcga
    12241 cagatgctag tatcgggggc gttgctctta accagattaa ccaattgcac tttgaccgtg
    12301 cctttatcgg aatgaatggt gttgacgatg gctattatac gactcctgat atggaggagg
    12361 gagctgtgaa aagagctatt ttggagaatg ccaagcagac ctacgtcttg gtggattcgt
    12421 caaaaattgg acaaacttgc tttgccaagg tagcaccact caaacgcgct atcgttatca
    12481 ctagtcaagg gcatgagctc ttgcaggtta ttaaggagaa aacggaggta atagaagtat
    12541 gatttataca gtcacactca atccatccat tgactatatc gttcgtttgg accaagtcaa
    12601 agttggtagt gtcaatcgta tggacagtga tgataagttt gctggtggga aaggaatcaa
    12661 tgtcagccgt gtcttgaaac gtttgaatat accaaataca gcgacgggat ttatcggtgg
    12721 ctttactggt aaatttatca cagatactct agcagaggaa gaaatcgaga cacgttttgt
    12781 ccaagtggca gaagatactc gtatcaatgt taaaatcaaa gcagaccaag aaacagaaat
    12841 caacggaacg ggtccaactg ttgaaccggt tcagctagaa gaattgaaag ctattttatc
    12901 tagtctgaca gtagaagata cagttgtctt tgcaggttca agtgctaaaa atctaggcaa
    12961 tgttatctat aaggatttga tttccttgac gcgccagact ggtgcgcaag tggtctgtga
    13021 ctttgaagga cagaccttaa ttgatagttt ggactaccag cctcttcttg taaaaccaaa
    13081 caatcatgaa cttggagcga tttttggggt taaactcgaa agtttagatg aaattgagaa
    13141 atacgctcgt gagttactgg ctaagggtgc tcaaaatgtt attatctcta tggctggtga
    13201 tggcgccctt cttgtcacat ctgagggagc ttacttcgct aaaccaatca aaggaacagt
    13261 caaaaattca gttggagctg gtgattctat ggttgctgga ttcacaggtg aatttgtcaa
    13321 atcaaaagac gcagtagaag ccttcaaatg gggagtggct tgcggaacgg caactacctt
    13381 ctcagatgac ttggcaacgg cggaatttat taaagaaaca tatggaaaag ttgaggtaga
    13441 aaaaagatga aaattcaaga cctattgaga aaagatgtca tgttgctaga tttgcaggca
    13501 actgaaaaaa cagctgtcat cgacgagatg attaaaaatt tgacagagca cggttatgta
    13561 acagattttg aaacatttaa agaaggaatt ttggcgcgtg aagctttgac ttctactggt
    13621 ttgggtgatg gaatcgcaat gcctcacagc aaaaacgctg ctgtcaaaga agcgacagtt
    13681 ctatttgcta agtcaaacaa gggtgttgac tacgagagct tggatggaca agcaactgac
    13741 ctcttcttca tgattgcagc tccagaaggt gccaatgata ctcacttggc agccttggca
    13801 gaattgtctc aatacttgat gaaagacggt tttgcagaca aacttcgtca agcaacatct
    13861 gcaggccaag ttatcgaact ttttgaccaa gcttcagaaa aaactgagga acttgttcaa
    13921 gcacctgcta atgactctgg tgactttatc gtagctgtta cagcttgtac aacaggtatt
    13981 gcccacactt acatggccca agaagccctt caaaaagtag ctgctgaaat gggggttggt
    14041 atcaaggtcg aaaccaacgg tgctagcggt gttggaaatc aactaactgc agaagatatc
    14101 cgtaaggcta aagctattat cattgcagca gacaaggccg ttgaaatgga tcgatttgat
    14161 ggaaaaccat tgatcaatcg tccagttgct gacggtatcc gtaagacaga agagctaatt
    14221 aacttggctc tttcaggaga tactgaagtc taccgtgccg ctaatggtgc caaagctgca
    14281 acagcctcta acgaaaaaca aagccttggt ggtgccttgt acaaacactt gatgagtggt
    14341 gtatctcaaa tgttaccatt cgttatcggt ggtggtatca tgattgccct tgccttcttg
    14401 attgacggtg ctttgggtgt tccaaatgaa aaccttggca atcttggttc ttaccatgag
    14461 ttagcttcta tgtttatgaa aattggtgga gctgcctttg gtttgatgct tccagtcttt
    14521 gcgggttatg ttgcctactc tattgctgaa aaaccgggtt tggtagcagg tttcgtggct
    14581 ggtgctattg ccaaagaagg ttttgccttt ggtaaaattc cttatgccgc aggtggtgaa
    14641 gcaacttcaa ctcttgcagg tgtctcatct ggtttcctag gtgcccttgt tggtggattt
    14701 atcgcaggtg ccttggttct tgccatcaag aaatacgtta aagttcctcg ttcactcgaa
    14761 ggtgctaaat caatccttct attgccactt cttggaacaa tcttgacagg atttgttatg
    14821 ctagctgtga atatcccaat ggctgcaatc aacactgcta tgaatgactt cctaggcggt
    14881 cttggaggag gttcagctgt ccttcttggt atcgtccttg gtggaatgat ggctgttgac
    14941 atgggtggac cagttaataa agcagcttat gtctttggta caggtacgct tgcagcaact
    15001 gtttcttcag gtggttctgt agccatggca gcagttatgg ctggaggaat ggtgccacca
    15061 cttgcaatct ttgtcgcaac tcttcttttc aaagataaat ttactaagga agaacgtaac
    15121 tctggtttga caaacatcat catgggcttg tcatttatca ctgagggagc gattccattt
    15181 ggtgccgctg acccagctcg tgcgattcca agcttcatcc ttggttcagc agtagcaggt
    15241 ggactcgttg gtcttactgg tatcaaactc atggcgccac acggaggaat cttcgttatc
    15301 gcccttactt caaatgctct cctttacctc gtttctgtct tggtaggagc aatcgtaagt
    15361 ggtgtggttt atggttacct acgcaaacca caagcataaa aaatagaaaa atgaaaagat
    15421 tggaccgttt ggtgcagtct ttttctcttc ccgaaatgcc tgtgaaatat ggtataatag
    15481 aagaatggca aacaagaata caagtacaac aagacggaga ccgtctaaag cagaactgga
    15541 aagaaaagaa gcgattcaac gaatgttgat ttcgttagga attgcgattt tattgatttt
    15601 cgcagccttc aaattagggg ctgcaggtat aaccctttat aatttaattc gcttgctagt
    15661 gggtagccta gcttatctgg cgatattcgg cctattaatc tatctcttct ttttcaagtg
    15721 gatacgaaaa caggaaggac tcttatctgg ctttttcacc atatttgctg gcttactctt
    15781 gatttttgag gcctacttgg tttggaaata tggtttggac aagtccgttc taaaagggac
    15841 catggctcag gttgtgacag atctgactgg ttttcgaacg actagctttg ctggaggggg
    15901 cttgatcggg gtcgctcttt atattccaac agcctttctc ttttcaaata tcggaactta
    15961 ctttattggt tctatcttga ttttagtggg ttctctccta gtcagccctt ggtctgttta
    16021 cgatattgct gaatttttca gtagaggctt tgccaaatgg tgggaagggc acgagcgtcg
    16081 aaaagaggaa cgctttgtca aacaagaaga aaaagctcgc caaaaggctg agaaagaggc
    16141 tagattagaa caagaagaga ctgaaaaaac cttactcgat ttgcctcctg ttgatatgga
    16201 aacgggtgaa attctgacag aggaagctgt tcaaaatctt ccacctattc cagaagaaaa
    16261 gtgggtggaa ccagaaatca tcctgcctca agctgaactt aaattccctg aacaggaaga
    16321 tgactcagat gacgaagatg ttcaggtcga tttttcagcc aaagaagccc ttgaatacaa
    16381 acttccaagc ttacaactct ttgcaccaga taaaccaaaa gatcaatcta aagagaagaa
    16441 aattgtcaga gaaaatatca aaatcttaga agcaaccttt gctagctttg gtattaaggt
    16501 aacagttgaa cgggccgaaa ttgggccatc agtgaccaag tatgaagtca agccggctgt
    16561 tggtgtaagg gtcaaccgca tttccaatct atcagatgac ctcgctctag ccttggctgc
    16621 caaagatgtc cggattgaag caccaatccc tgggaaatcc ctaatcggaa ttgaagtgcc
    16681 caactccgat attgccactg tatctttccg agaactatgg gaacaatcgc aaacgaaagc
    16741 agaaaatttc ttggaaattc ctttagggaa ggctgttaat ggaaccgcaa gagcttttga
    16801 cctttctaaa atgccccact tgctagttgc aggttcaacg ggttcaggga agtcagtagc
    16861 agttaacggc attattgcta gcattctcat gaaggcgaga ccagatcaag ttaaatttat
    16921 gatggtcgat cccaagatgg ttgagttatc tgtttacaat gatattcccc acctcttgat
    16981 tccagtcgtg accaatccac gtaaagccag caaggctctg caaaaggttg tggatgaaat
    17041 ggaaaaccgt tatgaactct ttgccaaggt gggagttcgg aatattgcag gttttaatgc
    17101 caaggtagaa gagttcaatt cccagtctga gtacaagcaa attccgctac cattcattgt
    17161 cgtgattgtg gatgagttgg ctgacctcat gatggtggcc agcaaggaag tggaagatgc
    17221 tatcatccgt cttgggcaga aggcgcgtgc tgcaggtatc cacatgattc ttgcaactca
    17281 gcgtccatct gttgatgtca tctctggttt gattaaggcc aatgttccat ctcgtgtagc
    17341 atttgcggtt tcatcaggaa cagactcccg tacgattttg gatgaaaatg gagcagaaaa
    17401 acttcttggt cgaggagaca tgctctttaa accgattgat gaaaatcatc cagttcgtct
    17461 ccaaggctcc tttatctcgg atgacgatgt tgagcgcatt gtgaacttca tcaaggctca
    17521 ggcagatgca gactacgatg agagttttga tccaggtgag gtttctgaaa atgaaggaga
    17581 attttcggat ggagatgctg gtggtgatcc gctttttgaa gaagctaagt ctttggttat
    17641 cgaaacacag aaagccagtg cgtctatgat tcagcgtcgt ttatcagttg gatttaaccg
    17701 tgcgacccgt ctcatggaag aactggagat agcaggtgtc atcggtccag ctgaaggtac
    17761 caaacctcga aaagtgttac aacaataaaa aaatagcttc tttccgagtt tggagggaag
    17821 ctattttagt ggctattgat tgcttttatt ttctgaagtt ggcgcattgg actgtttttc
    17881 gttttcagta gcaggtttac ttgaagcagg agtagaagag tcctgagttg ctgttttctg
    17941 atcttctttt ttctcttcct tgacgctaga ttttggtgtt tcctcttgct gtgttttttc
    18001 ttgactagtg ttagtctctt tagttggact ggtgttttcc ttaggggatt ccttttggat
    18061 ttctttgaca atggttgtcg tctggcttgt cgtaggttct tttttaatat ttttgttatt
    18121 atccaaggcg ttcatgatcg tgatacccgc ggtaatcaag ccaaggatac tagcgattgt
    18181 agcaacggtt ttttgaaaga ctgtaaagcc ttttttgatg tgttctgttt ttggttttga
    18241 agttctacga tagttagaca tacattctct cctttgatta tgatttatta tactctgttt
    18301 ctttaaaaaa atcttaaaaa aagagaaatt gccctttctt gtcgcaggct ccgtttcatg
    18361 atacaataga aggagtgatt ttagaaagcg tgagaaacat gatttacttt gataattcgg
    18421 cgacgaccag gccctatcca gaagcccttg aaacctatat gcaggtggct tcaaaaattt
    18481 taggaaatcc atctagtctc catcgtttgg gagaccaggc aacacgaatt ttagatgctt
    18541 cccgtcaaca gattgcagat ttaatcggta agaaaagtga tgaaatcttc tttacatctg
    18601 gtgggacaga aggggataac tggatcatca agggagtagc atttgaaaaa gcccagtttg
    18661 gcaagcacat catcgtatca gccattgaac atccagcagt taaggaatca gccctctggt
    18721 tgaaagctca aggttttgaa gtggattttg ctccagttga taacaaagga tttgtggatg
    18781 ttgaggcgct agaagatttg ataagacctg atacgaccct cgtttccatc atggcagtta
    18841 acaatgaaat tggctctgtt cagcccattg aggctatttc aaaactattg gcagacaagc
    18901 caactatttc cttccacgtt gatgcggttc aggcgcttgc caagattccg actgaaaagt
    18961 atctgacaga acgagtggat ttcgcgactt tctctggtca caagttccac ggaatccgtg
    19021 gtgttggttt tatctatatc aagtctggca agaagattac gcctctttta acaggtggtg
    19081 gtcaggaacg tgattaccgt tcgacaactg aaaatgtggc aggaattgca gcgaccgcta
    19141 aggctctccg tttatctatg gaaaagctag atatctttag gagcaagact gggcagatga
    19201 aggcagtgat tcgtcaagca cttctggact atccggatat atttgtcttt tcagatgagg
    19261 aagacttcgc ccctcatatt ctgacttttg gaatcaaggg tgttcgtggt gaggtcattg
    19321 ttcacgcctt tgaagactat gatattttca tctcaacgac ctcggcttgt tcgtccaagg
    19381 ctgggaaacc agccggaacc ctgattgcta tgggagtgga caaggataag gctcagtcag
    19441 ctgtgcgtct tagtctagac cttgaaaatg atatgagtca ggtcgagcag ttcttgacca
    19501 agctaaaatt aatttacaat caaactagaa aagtaagata ggagcattca tgcagtattc
    19561 agaaattatg attcgctacg gtgagctgtc aaccaagggc aaaaatcgta tgcgtttcat
    19621 caataaactt cgcaataata tttcagacgt tttgtctatc tatccccaag ttaaggtaac
    19681 agcagatcgc gaccgtgccc acgcttacct caatggagca gattacacag cagtagcaga
    19741 atcgctcaaa caagtatttg gaattcaaaa cttttcccct gtttataagg ttgaaaaatc
    19801 tgtagaagtt ctgaagtctg ctgtccaaga gattatgcag gacatctaca aggaaggcat
    19861 gacctttaaa atctctagca agcgtagcga ccacaccttt gaattggaca gtcgtgaact
    19921 caaccaaacg cttggaaggg ctgtattcga agccattcca aacgtacaag ctcaaatgaa
    19981 aagtcctgac atcaatcttc aggtggagat acgtgaagaa gcagcctatc tttcttatga
    20041 aaccgttcga ggggcaggtg gattaccagt gggaacttct ggtaagggca tgctcatgtt
    20101 gtcaggggga atcgattccc ctgtagctgg ctatctagcg cttaaacgag gggtagatat
    20161 agaggcagtt cactttgcca gcccacctta cacgagtcct ggtgctctta aaaaagccca
    20221 agatttgacc cgtaaattaa ccaaatttgg gggaaatatc cagtttatcg aagttccttt
    20281 tacagagatt caagaggaaa tcaaagccaa agcgccagaa gcctacctta tgaccttgac
    20341 gcgtcgtttt atgatgcgta ttactgaccg tattcgtgag gtacgaaatg gtttagttat
    20401 catcaatggg gaaagtctag gtcaagtagc cagccaaacc cttgaaagta tgaaggctat
    20461 caatgctgtt accaacactc ccatcattcg tcctgtggtt accatggaca agttggaaat
    20521 cattgacatc gcccaggaaa tcgatacctt tgacatttca atccaaccgt ttgaagactg
    20581 ttgtaccatt tttgcaccag atcgtccaaa aacaaatcct aaaattaaga atgcggagca
    20641 gtacgaagcg cgtatggatg ttgaaggctt ggttgagcga gcagtggctg gaatcatgat
    20701 tactgaaatc acacctcaag ccgaaaaaga tgaagttgat gacttgattg acaatctgct
    20761 ctaattcaga aaatccaaaa gaatagcgaa aatcagtaaa aaaagttagt tttttctcta
    20821 aaaacaggta aaaaactaac tttttttatt tttatgatat aatgatataa aattttgaat
    20881 atagagagtt ttctggcaat gaatcaatcc tacttttatc taaaaatgaa agaacacaaa
    20941 ctcaaggttc cttatacagg taaggagcgc cgtgtacgta ttcttcttcc taaagattat
    21001 gagaaagata cagaccgttc ctatcctgtt gtatactttc atgacgggca aaatgttttt
    21061 aatagcaaag agtctttcat tggacattca tggaagatta tcccagctat caaacgaaat
    21121 ccggatatca gtcgcatgat tgtcgttgct attgacaatg atggtatggg gcggatgaat
    21181 gagtatgcgg cttggaagtt ccaagaatct cctatcccag agcagcagtt tggtggtaag
    21241 ggtgtggagt atgctgagtt tgtcatggag gtggtcaagc cttttatcga tgagacctat
    21301 cgtacaaaag cagactgcca gcatacggct atgattggtt cctcactagg aggcaatata
    21361 cccagtttat cggtttggaa taccaagacc aaattggttg cttgggcgtt ttttcatctg
    21421 caaactggct ccaccaagaa gcctttaacc gctatatcga gtgccagaaa ctatcgcctg
    21481 accagcgcat cttcatctat gtaggaacag aagaagcaga tgatacagac aagaccttga
    21541 tggatggcaa tatcaaacaa gcctatatcg actcgtcgct ttgctattac catgatttga
    21601 tagcaggggg agtacatctg gataatcttg tgctaaaagt tcagtctggt gccatccata
    21661 gtgaaatccc ttggtcagaa aatctaccag attgtctgag attttttgca gaaaaatggt
    21721 aagttaagaa aggaaaaaac gaaatgcata ttgaacatct tagccactgg agtggtcatc
    21781 ttaaccgtga aatgtacctt aaccgttatg gacatggtgg gattccagtt gtggtctttg
    21841 cttcatcagg tggtagtcac aacgaatact atgattttgg catgattgat gcctgtgctt
    21901 cctttatcga ggaaggcctt gtccagttct ttaccctatc tagtttggat agtgagagct
    21961 ggttggttac ttggaaaaat gctcatgacc aagcggaaat gcaccgtgcc tacgaatgtt
    22021 atgtgattga ggaggccatt cttttatcaa gcacaagaca ggttggtttg atggcatgat
    22081 gacgacaggt tgctctatgg gagcctatca tgcactcaat ttcttcctcc agcatccaga
    22141 tgtctttacc aaagtgattg ctctcagtgg tgtttacgac gcacgtttct ttgtcggtga
    22201 ttactacaac gatgatgcta tttaccaaaa ctcgccagta gattatattt ggaaccaaaa
    22261 cgacggctgg tttattgacc gttaccgtca ggcagagatt gtgctgtgta cggggcttgg
    22321 agcctgggaa caagatggtt tgccatcctt ttacaagctc aaagaagcct ttgacaagaa
    22381 acaaattcca gcctggtttg ctgaatgggg acatgatgtc gcccatgact gggaatggtg
    22441 gcgtaaacaa atgccttatt tcctcggtaa tctctattta taaaaggagt tacctatgaa
    22501 ttaccttgtt atttctccct actatccaca aaactttcaa cagtttacca tcgaactagc
    22561 taataaaggc atcacagtct tgggaattgg tcaagagtct tacgagcaat tggatgagcc
    22621 cttgcgcaat agcttgaccg agtattttcg tgttgataat cttgagaaca tagatgaagt
    22681 caaacgtgca gttgcttttc tcttttataa acatggtcca attgaccgca tcgagtctca
    22741 caatgaatac tggcttgagc tagacgcaac actcagagaa caattcaatg tttttggtgc
    22801 caaaccagag gatctcaaaa agacgaaata taagtctgaa atgaagaaac ttttcaaaaa
    22861 agcaggtgtt cctgtggtac ctggagctgt tatcaagacg gaagcagatg ttgatcaagc
    22921 agtgaaagaa atcggtcttc caatgattgc caaacctgat aatggagtgg gagcagccac
    22981 aacctttaaa cttgagacag aagacgatat caatcacttc aagcaagaat gggaccattc
    23041 aaccctttat ttctttgaaa aatttgtcac ttccagcgaa atctgtacct ttgacgggct
    23101 cgtggacaag gatggaaaga ttgtcttctc aacaaccttt gactacgcct atacaccgct
    23161 tgacctcatg atttataaga tggacaattc ttattatgtg ctcaaggata tggatcctaa
    23221 actgcgcaag tatggggaag caattgtcaa agaatttggt atgaaagaac ggtttttcca
    23281 tattgagttc ttccgtgagg gggacgatta tattaccatc gagtacaata accgccctgc
    23341 aggtggtttt accattgatg tttataactt tgctcattcc ttggacctct atcgtggcta
    23401 tgcagctatt gtcgcaggag aggagttccc ggcgtcagac tttgaaactc agtattgttt
    23461 ggctacttct cgccgtgcaa atgctcacta tgtttattca gaagaggatt tgcttgccaa
    23521 atatagccag cagttcaaag ttaaaaaagt catgccagct gccttcgcgg aacttcaagg
    23581 agattacctg tatatgctga ccactccgag tcgacaagaa atggagcaga tgattgcaga
    23641 tttcggacaa cgtcaagaat aagaactatc ggattaagga aattaactcc cttaatcctt
    23701 ttgttttgtc tgataaaaaa taagagcatc ccaacaaggt agctatcata aaacttgttc
    23761 gataactatt tgaagcagga ttaggtggtc agaaattgaa ttttaatatt tcaattgagt
    23821 catagtattg tgtttgcgta tccttaaatc agctaaaagg atccatgacg acacctatac
    23881 gatatagttt tcaagatacc aaacaagtct attaatactc aatgaaaatc aaagagcaaa
    23941 ctaggaagct agccgcaggt ttctcaaaac actgttttga ggttgtggat agaactgaca
    24001 gagtcagtat catataccta cggcaaggtg aagctgacgt ggtttgaaga gattttcgaa
    24061 gagtataaaa tattcaggtg acgcatagat atagttaatt gaagctttgt ttgaaatctg
    24121 ataaaataat gatattacta agttttaaaa actaaagaaa agggaagata tgattacagg
    24181 cgaattaaaa aataaaatcg atcagctgtg ggaaattctt tggacagaag gaaacgcaaa
    24241 tcctttaaca aatattgaac agttgactta tctcttattt atgaaagatt tggatagtgt
    24301 cgagcttgga cgtgaaagtg atgctgaatt tctagggatt ccttatgagg gagtttttcc
    24361 aaaagataaa cctgaatacc gttggtcaac ttttaaaaat ataggagatg ctcaggaagt
    24421 ttatcgttta atgactcagg agatttttcc gtttattaaa aatctcaagg gggatacaga
    24481 tgatacagcc ttttcacgat atatgcgaga agctattttt caaataaata aacctgctac
    24541 gcttcaaaag gcaatttcta tcttagatgt ttttccaact aggggattag atgtagattt
    24601 tgataatgac aaacaaagta ttactgatat cggagatatc tatgaatatc tgttatcaaa
    24661 attgtcgacc gcaggtaaaa atggacagtt ccgtacacct cgtcacatca tcgatatgat
    24721 ggttgagttg atgcaaccga ctatcaaaga tatcatctca gatcccgcta tgggttctgc
    24781 tggcttctta gtatctgcta gccgttactt aaagcgtaag aaagatgaat gggaaaccaa
    24841 tacagataat atcaatcatt ttcataatca gatgtttcat ggaaatgata cggatacgac
    24901 tatgttgaga cttggggcga tgaacatgat gctacatgga gtagaaaatc cacaaatcag
    24961 ttaccttgac tcgctgtctc aagataatga agaagccgat aaatatactt tggttttagc
    25021 aaatcctcct tttaagggct cacttgacta caattcaacc tctaatgacc ttcttgcaac
    25081 cgtaaaaacc aaaaaaacag aattactctt tctttctctt ttcttgcgaa ctttaaaacc
    25141 aggtggacga gcagcagtta tcgtacctga tggtgtcctt tttggttcgt ctaaagctca
    25201 taaaggaatt cgtcaggaaa ttgtagagaa tcataagctt gatgctgtaa tctcaatgcc
    25261 tagtggtgtg ttcaagcctt atgctggagt ttcaactgct attctcatct ttacaaaaac
    25321 tggtaatggt ggtactgaca aagtctggtt ttacgatatg aaagcggatg gtttaagttt
    25381 ggatgataag cgacaaccga ttagcgacaa tgatattcca gatattatcg aacgctttca
    25441 tcatcttgaa aaagaagcag aacgtcagag aacggatcaa tctttctttg ttccagttgc
    25501 tgagataaag gaaaatgatt atgatttgtc tatcaataaa tataaagaga ttgagtatga
    25561 aaaagttgag tatgaaccaa cagaggtcat cttaaagaaa atcaatgatt tagaaaaaga
    25621 aattcaagct ggcttggctg aattagaaaa attactcaag tagggaggtg gctgtatgaa
    25681 aaaagtgaag ttgggggaag tcttatctct aaaaaaagga aagaaagcca ctgtacttgc
    25741 tgaacaaaca actctaagcc aacgttatat tcaaatagat gatttaagaa ataataataa
    25801 tttaaaattc actgaaagtt taaatatgac tgaagcactc ccagatgata ttctaatagc
    25861 atgggatggt gctaatgcag gaacagttgg ctatgggtta tcgggagctg ttggtagtac
    25921 aattacggtc ttaaaaaaga atgagcgata caaagaaaaa attatatcag attacttggg
    25981 agtctttttg gaaagtaaat cgcagtattt acgagatcat tcaacaggtg caactattcc
    26041 tcatttaaac aagaatatat tacttgattt acaattagaa ttgctaggta tcgaagaaca
    26101 agagaacatt atctgtattc ttaatacgat taaaaggctt attactaaaa gaaaatttca
    26161 gttagatgaa ctaaacttgc tcgtcaaatc ccgatttaac gagatgtttg gggatccttt
    26221 aaataataac aagaaatttg cagtaaaaac gggacaacag tgttttaaat tttcaagtgg
    26281 aaaatttctt gataaacatg atagagtttt tgaaggttat cctgcctatg gtggaaatgg
    26341 cattgcttgg aaaagtcgaa aatatttaat tgataatcct actatcatca ttggtcgtgt
    26401 aggtgcatat tgtggtaatg taagaactac ccacggtaag gtatggataa gtgacaatgc
    26461 tatatatata aaagaattta agaattccga tttcaatctt gtatttttat tagaattaat
    26521 gaaagtaatt gattttagta aatttgctga tttctcaggt caaccaaaga taactcaaaa
    26581 accattagaa aatcagaaat atatcctccc ccctctagcc ctccaaaatg agttcgcaga
    26641 ctttgtagcc ctggtcgaca aatcacaatt ggcaatccaa aaatctctgg aagaacttga
    26701 aactttgaag aaatctctga tgcaggagta ttttggctga tattctgcca ttgtaattac
    26761 ggtaatgatt tgttataata cttcaaagga ggaaatcaga tggtagtaaa aacaagaaaa
    26821 caaggaaatt caatcaccat tacgattcca agtgaattta atattccaag tggtgttaaa
    26881 tacgaagcga aattgttacc aagtggtgag attatcttta ctcctgaaga attggggcag
    26941 caggtttctt atgtatctga tgatgccttt gacttaaatt tagataaaat atttgacgaa
    27001 tacgacgatg ttttcaaagc tttggtggaa aaatgacaat ctatctgaca gaaaagcaaa
    27061 ttgaaaaaat aaatgcttta gcaattcaac ggtattctcc aaatgagaaa attcaaacag
    27121 ttagttcttc tgccttaaat atgattgtga acttaccaga acaatttgtc tttgggaagt
    27181 ctctttatcc aacaattttt gataaagcaa cgatactatt tgtccaattg ataaagaagc
    27241 atgtttttgc taatgctaat aaaagaactg ctttcttcgt tttggtcaaa tttttacaat
    27301 taaacggcta tcgtttttct gtaacggtag aagaagcagt aaaaatgtgt gtaaccatcg
    27361 cagtagaagc tttaactgat gaaaaaatga caagctactc caaatgggtt tctgaacatt
    27421 ctgttagaga aaaggtcaaa aagtaaccta gtatgctgga tttgaatgag cacaagaaaa
    27481 taaatgaaca gacaatatta gaattctgta atgcagaaac tgatattgtc tctttttatt
    27541 gatgaataag aaagtgagaa attatggaat caaaagttac aattatcatg caagaaatgt
    27601 tacctctttt aaataatgaa caattactag cgttgagaga gagtttagaa catcatctag
    27661 tagacggaaa aaagcagcag aagtattcga ataataacct gttgcaacta tttattaccg
    27721 ccaagcaggt agagggctgt agctcaaaaa caattcgtta ttaccagagg acgattgaaa
    27781 acttgtttaa tgctattaaa gagtctgtga cacaactcac aacagatgat ttaaggagtt
    27841 atttagcaaa ttaccagtct gaaaaggatt gtagtaaggc aaatttagac aatattaggc
    27901 gtatattgtc ttcttttttt gcttggcttg agcaagagga atatatcatt aaaaatccca
    27961 ttcgacggat aaagaaaatt aagactgagc aaaatgtgaa ggaaacttat actgatgaac
    28021 atttggaaat tatgcgtgat aactgtgaaa atttgagaga tttggcaata atagacctac
    28081 tagcatcgac aggtatgcgt gtaggggagc ttgtacagtt gaatcgttca gatattgatt
    28141 ttgaaaacag agagtgtgtt gtctttggta aaggaaagaa ggagagacca gtatattttg
    28201 acgctcggac gaaaattcat ttaagaaatt atcttaacga cagaaaagat agtcaccctg
    28261 ctctttttgt aacgctagtt ggaaaagccc agagacttgg aattgctggt gtagagattc
    28321 gcttaagaaa gttaggagac aaactcggca tacaaaaggt tcacccacat aagttcagaa
    28381 gaactttagc gactaaggca attgataaag gtatgcctat cgaacaagtc caaaaactgc
    28441 taggtcatag caagattgac acaaccttgg cctatgccat ggtcaatcaa aataatgtca
    28501 agcattcaca ccaaaaattc atctcttaaa agcaaattcc cgatttaacg agatgtttgg
    28561 ggaaaataaa atatttgaaa gcattgataa cttatttgat attatagatg gtgatagggg
    28621 caaaaattat cctaaatcag atgagttgtt tagtgaggag tactgtttat ttttaaatac
    28681 aaagaatgtt actaaaaacg gattttcatt cgatacaaag caatttatca ctaaaacaaa
    28741 ggataaatta cttcgaaaag gcaaacttga gcgttatgat atagtcttga caacaagagg
    28801 tactgttgga aatgtagcgt actacgatga attaataaaa tataaacatt tacgtataaa
    28861 ttcaggtatg gtaatattac gtcccaagac accaaatcta aatcagaaat ttattatcca
    28921 tgttttaagg aataataatt atagtcgagt gatatcagga agtgctcagc ctcagttacc
    28981 aattacaaaa ttaaaaaaaa tacttctccc cctcccccca ctagccctcc aaaatgagtt
    29041 cgcagacttt gtagtccagg tcgacaaatc acaatttgct tgtgagatag ctatataaaa
    29101 gtgtggagaa atagcttgaa atttagtata atatagctaa actatttgtt taaagtgaga
    29161 aaaaaatggg aaattttagc tttcttttaa aaaatgacga atatgaatct ttttcaaaac
    29221 cttgcattga agctgagaat atgattgcta catcaactgt ggctactgcc tttatggcgc
    29281 gtcgtgcttt agagcaggct gtccattgga tatatagtca cgattcatat ttagaagctc
    29341 cctatcgtgc tactctatct tctttagtat gggatgatga ttttagggat atcgtagatt
    29401 ctgaactcca caagcagata gttctgttga ttcggtgggg aaaccatgct gctcatggtg
    29461 gtgaaattaa ggaacgagaa gcgattttag ctttgcatca tttgtatcag tttgttaatt
    29521 ttatcgatta ttgttacagc aatgagtttg tggagcgtta ttttgatgag aagtgcttac
    29581 cactttcagc aaacatcaaa taccgagaaa ctccacaatc tatgataaag ttacaagaca
    29641 gtttaccaga actgcctgat tttcatgaac agatggctgc tcagtccgta gaagttcaag
    29701 agacttatac tgaaaaacgt gagactgcag cgcaacggca agatgtgcct ttccatattg
    29761 atcaattatc tgaggcagag acaagaaagc tctttattga tatcgatctc cgtttagcag
    29821 gatggatatt tggagaaaac tgttgtgttg agatagccgt tgatggtctc aagcacggtt
    29881 caggaattgg ttactgtgac tatgtacttt atggtaaaaa tgggaaaatt ttagcgattg
    29941 tggaggctaa aaaagcctct gtcaatccag aagtagggga agtacaggtc aaagaatatg
    30001 ctgaagcttt ggagaaacat atcggctatc agccaatttg ctttattaca aatgggttga
    30061 agcactatat acttgatggt ccgaaccgac gccagattgc aggcttttac tctcaagaag
    30121 aattgcaatt agtgatggat agacgtcatc ttcaaaaacc acttgaggat atttctagta
    30181 aaattaggga cgatatttcc gggcgtcact accaaaaaca tgccattgca agcgtttgtg
    30241 aagctttctc taatcatcgt agacaggcac ttttggttat ggcaactggg gcggggaaaa
    30301 ctcgtacagc agtttctcta gttgatatct tatcacgtca taactgggta aaaaacgttc
    30361 tcttcttagc cgatagaact tccttggtta agcaagccta tgattcgttt agaaaattac
    30421 tcccagatct ttccgtttgt aacttcttag aagataaaga aggagctcaa tcaagtcgta
    30481 tggtcttttc aacttatccg accatgattg gagcgattag tggtcaagaa gaagtaaatc
    30541 aacgcccttt tactgttggg cattttgacc ttatcataat tgacgaatct caccgttcta
    30601 tttatcagaa atacaagtcc atttttgatt attttgatgc aagaattgta ggcttaacag
    30661 ctactccgcg tcaagattta gataaaaaca cctatggatt ctttaatttg gagaatgggg
    30721 ttccaacata tgcatatgat ttggaagagg ctgttaaaga cggatattta gtagcctatc
    30781 attctatcga aaccaaactg aaactaccta cggatggtct acattatgat gatttgtccg
    30841 aagaagaaaa ggaacatttt gatagcaaat ttgaagacga tagctgtgaa aaagatattg
    30901 atgggagtgt atttaattcc tttgttttca ataaaagtac agtagaaatt gttttaaatg
    30961 aactcatgac aagaggaatt cagacagcct cgggtgatga aattggtaaa actattattt
    31021 ttgctaaaaa tcatgatcat gcagaatata tcagaggtat ttttaacaac cgctatcctg
    31081 aaaaagggag cgactatgct caggtgattg attatagtat taagcattat cagaccttga
    31141 ttgatgattt taaaattgag gagaagtatc ctcaaattgc gatttctgtc gatatgttag
    31201 atacaggtat tgatgtacca gaggttgtta atttagtctt cttcaagaaa gtacgctcta
    31261 aaactaagtt ttggcagatg attggtcgag gaacccgtct atgtaaagat ttatttggac
    31321 ctgagcagga taaggaaaac ttcttggtat ttgattatgg ggataatttt gattattttc
    31381 gtgcagatcc aagagatgga gagggtcgtc acattgtttc gttgactcag cgtttattta
    31441 atatcaaagt ggacttgatt cgagaacttc agggactcca ataccaagaa gatcagtttg
    31501 cgagagcata ccgtcagcag cttgtctcgg aacttcaagg tcgtatagag agcttaaatg
    31561 agttggactt cagggttcgt atggttttag atacagttta tagctatagg aaattggaaa
    31621 gttggcagaa tctaactgct gttacaagtg aaaccattca aaaaaatctc tctccgcttt
    31681 tatttgatga agataaagaa gatgagatgg ccaggagatt tgatttgtgg ttgcttcata
    31741 ttcagttggg gcaactgaca gctaaatctt ccactgttca tatttcccaa gtgatgaaga
    31801 cggctagagc tctttctgct attggcaata tcccgcaggt ttttgagcag gctgaaatta
    31861 tcaggaaagt acaggagcct gaattttgga aagaagttaa cttgtctgat ttggaaaaaa
    31921 ttcgtcttgc tattcgagat ttattacagt ttttggataa aacagaccgt aaaccctact
    31981 atgttaactt tgaagatcgt atactctcca ctgttcacga gaccacagca tttttgcagg
    32041 tcaacgatct tcggtcttac aatgaaaaag ttgagcatta tttgaaaact catctggatg
    32101 aggagtccat ttctaagcta taccataata aaaagttgac atctgatgat atgcttgcac
    32161 ttgaaaaatt gctttgggaa aaattaggta gtaaagcaga ctaccaaagt cattatgaaa
    32221 ataaggcaat tccgagattg gttcgtgaga ttattggctt agatagagag tctgccaatc
    32281 gtattttttc taaatttttg tcggatgaga atcttaatgc caggcagatt tcatttgtaa
    32341 aattgattgt agactacatt gtagaaaatg gttttttaga gacgaaagtg ttaacgcaag
    32401 agccgtttaa atcttatggt tctgttcaac tactcttcca acaccaacta ccagtacttc
    32461 gtaatattgt tcaaatcatt gaacttatca ataatcgagc tggagaagcg gcttaaattc
    32521 taaagtgatt gccatgctga gactcattta aaattaaaaa gagtagaaat ttatgctata
    32581 tatgagaagt tttattagga agaatgtcat cgttttccta gaatacagta tcagttgtta
    32641 agtggttgat aaatttcaaa gtagatactt gtaccacgat gtttgttgat cgagttatta
    32701 acaaaagagc tactttgatt ttaaagaaat agaaaacaaa aagccgagca agaattcaat
    32761 tgcaggagaa aatgaaataa tactcaatga aaatcaaaga gcaaactagg aaactagctg
    32821 caggctgctc aaaacactgt tttgaggttg cagataagac tgacgaagtc agctcaaaac
    32881 atggttttga ggttgtagat gaaactgacg aagtcagtaa ccatacctac ggcaaggcga
    32941 cgttgacgcg gattgaagag attttcgaag agtataaatc ttcctaggat aaagcaaaac
    33001 gcatagtatc aagggttttc aacacttgat actatgcgtt ttctgatgtt aaagactttc
    33061 taccagtttt tttaagcata attgttagtt gtagtcattt attattcttc aaagaaaaat
    33121 ggtggggcga attttttcag ttcttcaaag cacttttgag cagtatctgc atcttcacag
    33181 atgataagac agacatcatt accacaaagg gtagcgatag cgtcagggaa gctcaaagta
    33241 tcaatgatag aaccaaagga ttgagccagt ccaggaaggg tttttagtag gacttggtgt
    33301 tgaactgggc gcatccagac aagggcgtct tccatgtaga gttcgagacg tttttcccat
    33361 tttgagatgg aaccattgtt aagaacataa taagcgctat cttcttcgcg gacttttgat
    33421 aggttcatat ttttgatgtc gcgtgagagg gttgcctggg ttacttgaat gtcgttctta
    33481 gcaagaaggg cttgcaactc agcctgtgta tgaatcttgt tttttgtgat aagagcgcgt
    33541 ataagttggt ggcggtgttc tgatttattc ataataatgt aactcctttt agcaaggtaa
    33601 ggtaagcatg gactgagcga ggtcgacagt caagtggtag tctgtattgt cacggatggt
    33661 gatttcaaag tcagtagtat agaggactaa acggagagtg tctccttctt ttagcttgta
    33721 aatagttggc tgcagttcaa attgaacatc catccattca tctgcagtaa tatcctctac
    33781 taacagtaaa tcatttctat tttgtaaatt aaggtaacct tttgtcacga ctcgttgtgc
    33841 ctctggtcta aatggcaatt cacagagatt ttccaacatg tgatagcgac cgttgtcaat
    33901 ggttctagca cttaaaatag ctggataagg ttgtaggtat ttcttttgcc caaattctag
    33961 cagttgggca gataagagcc ccttgtttgt actggatttg atacgaagat tgagctgagc
    34021 gcgaccgttt aggtggagat ctttagtcac aggaaggtta atagtaatct gattggcttt
    34081 cccttgatag agctctgtat tgaaggtttg gtatgtctta ccatagcgct caaaatcctt
    34141 atctgggtac tggttttgaa tagcttgctc ttcttgacca agtgagaagg tttcacagtt
    34201 ttcttgccca ccgaagttat caagtgataa ccaagtctgt ggagctgtat tgtcctgcca
    34261 gataacagta ggaagttgaa agtctgtttc ctgtcctagt aatttcttgg tcaataaggc
    34321 atttatggac tcacggaagt caattgattg ccaattgttc atgtaaacat gggcaccatt
    34381 atggaaaaag agatgcttgt ttatatgagt aggaagagca tggaacatct ggtaaacatg
    34441 aagtggtttg acattccaat cctgagaacc atgagtaaag acaacctctg cctttacttt
    34501 atgggcattg agcagataat tgcggtcatg ccaaaactga ttgtagtccc cagtttttcg
    34561 gtctagctga gctttcactt tttctaagtc agcttggtga gcttcattgc cacggatata
    34621 gtcgccagct aagagattac gagaataggt taactcagca agggagtcaa agtcctcacc
    34681 tggataacca cctgggctag tcaccagacc gttttcacgg tagtagttgt accatgatga
    34741 aattcctgcc tcggcaatga taacttctaa accatcgact cctgtagtcg caagaccatt
    34801 ggacatggta cctagatagg aaagtcctgt tgtagcaact tttccgtttg accaatcagc
    34861 cttgacttga cgctggcgcg tgtgatcagt aaaggcacgg caacggccgt taagccaatc
    34921 gatgacattt ttataagcct cgatttgctg gtagtctcca ttagtcatga aacctgtcga
    34981 gtctttggta ccaacacctg agacatagag attggcaaag cctctcggaa ggaagtagtc
    35041 gtttagtgta tagctagagt tgatgtgagt tagcttttcc tcagcctctg ctataagctc
    35101 agctttacct tggggttgga cgagatttag ttgaggtttc tctagctcaa tcttgtgagg
    35161 aagcttaacc tcaagctcgc cctccatctt gtagagagcc ttgtcactag ccttgtcatt
    35221 ggttccctga tgataagggc tggctgtcat gatggcaggg atttttccat caaaacgagg
    35281 gcgaataatg ctaaccttta ctaggtctga tagccctttt tggtcagtat cgacacgaga
    35341 ctcaacgtaa acgacttcac gaatgacatc ctggttagaa aaagtagcca aactcttgcc
    35401 gttaaagtag tggtagtcat tatcctccgg aataagacca tcactaacaa gttggtcgat
    35461 aagagtattt ccttttttgg tgcgagtatt gagtaactga tagagatttt caatcaagtc
    35521 accatatata atgggaaatc cagtttcttt acgaaaaacg tcactatctt cgaagtcaac
    35581 caaataagaa aagcctaaaa gttgaaaagc aacagtataa aaaatatctg ctgtcagttc
    35641 atcttctgat tgaaaaaatg tcagcaggtc tgttttttta tcagctgcta ggatagaaag
    35701 tgggtagttg gtgtcttgat aagtgaaaaa gaaacgacgt aaaaaggttt caagtgagtc
    35761 tttgtgattg gctgtatttt gtaaatcaaa gccacatttt tttagttcag ataagacatt
    35821 ttcttttgga aaattgatat aactatattg attaaaacgc atagaacctc catatagaat
    35881 gacagttaag gttattatat caaaaaaaaa gcagaaaggg aattgttaac ttcaaaagga
    35941 aataatccaa taaaaatgaa taaagtacta aattcaatat agagaacaga gtaacaataa
    36001 gaataaatag atagggtata
//
LOCUS       DAVKMJ010000023        35367 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000023 DAVKMJ010000000
VERSION     DAVKMJ010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35367
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.023"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            225..878
                     /locus_tag="VW348_001166"
     CDS             225..878
                     /locus_tag="VW348_001166"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEU9746065.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            888..1352
                     /locus_tag="VW348_001167"
     CDS             888..1352
                     /locus_tag="VW348_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEU9746066.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1365..2633
                     /locus_tag="VW348_001168"
     CDS             1365..2633
                     /locus_tag="VW348_001168"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEU9746067.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIASEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRFVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2647..2907
                     /locus_tag="VW348_001169"
     CDS             2647..2907
                     /locus_tag="VW348_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746068.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2918..4279
                     /gene="pdrM"
                     /locus_tag="VW348_001170"
     CDS             2918..4279
                     /gene="pdrM"
                     /locus_tag="VW348_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEU9746069.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPIILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDNIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4433..5401
                     /locus_tag="VW348_001171"
     CDS             4433..5401
                     /locus_tag="VW348_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEU9746070.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGSVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5417..6409
                     /locus_tag="VW348_001172"
     CDS             5417..6409
                     /locus_tag="VW348_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEU9746071.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEEISVEIVDPRTLVPLDKDIIINSVKKTGKVILVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCSGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKD"
     gene            6627..7670
                     /locus_tag="VW348_001173"
     CDS             6627..7670
                     /locus_tag="VW348_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEU9746072.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7734..9419
                     /gene="lpdA"
                     /locus_tag="VW348_001174"
     CDS             7734..9419
                     /gene="lpdA"
                     /locus_tag="VW348_001174"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEU9746073.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHSAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVAVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDVEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9483..10472
                     /locus_tag="VW348_001175"
     CDS             9483..10472
                     /locus_tag="VW348_001175"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEU9746074.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEAVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10545..11615)
                     /gene="xerS"
                     /locus_tag="VW348_001176"
     CDS             complement(10545..11615)
                     /gene="xerS"
                     /locus_tag="VW348_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEU9746075.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVSDEQKNALDSL"
     gene            complement(12123..13673)
                     /locus_tag="VW348_001177"
     CDS             complement(12123..13673)
                     /locus_tag="VW348_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEU9746076.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(13689..14468)
                     /locus_tag="VW348_001178"
     CDS             complement(13689..14468)
                     /locus_tag="VW348_001178"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEU9746077.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIVGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKEN"
     gene            complement(14455..15306)
                     /gene="ylqF"
                     /locus_tag="VW348_001179"
     CDS             complement(14455..15306)
                     /gene="ylqF"
                     /locus_tag="VW348_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEU9746078.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWCQYFESQEIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(15552..20801)
                     /locus_tag="VW348_001180"
     CDS             complement(15552..20801)
                     /locus_tag="VW348_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU9746079.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVIGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVQPALPEAVVTDKGEPEVQPTLPEAVVTDKG
                     EPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVGTTGVDENGNLIEPPVNDIPEYTEP
                     ISTVSEVASEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVKEVGEDGERQIVT
                     SYEELHGKKISEPVETVTILKEMKPKILVKGTKENPKEKTVPVLTLTKVTEDAMNRSA
                     NLNYELDNKDNAEISSIIAEIKDGDTVVKKVDLSKEKLTDAVQNLDLFKDYKIATTMI
                     YDRGQGSETSKLDEKTLRLELKKVEIKNISSTNLVKVNDDGTEIPSDFMSEKPSDEDV
                     KKMYLKITSRDNKVTRLAVDKIELVTEKEKELYKITASAQDLIQHVDPSKTRNEYIHY
                     IEKPVPKVNNVYYNFNELVRDMQEHPNDEFKLGADLNATNVSAFGKSYVTKDFKGKLL
                     SDGDNHYTIHNLSRPLFGNVIGGTIKNINLGNVDINMPWANQVAAVANIIKGGTTIEN
                     VKVKGNIVGKDWVSGFIDKIDNQGTLRNVAFIGNVTSVGDGGQFLTGIVGENWKGLVE
                     RAYVNANLIGKKAKAAGIAYWTQNEGNNNTVRQEGAIKKSIAKGTIQVTEAIESGGVV
                     GSMKHHGSVEDSVSMMKVPNGEIFYGSSDIDYDDGYWTGDNVRRNYVVIGVSDGHSSY
                     QRSKDKNRIRPISEEEAKSKIEATGITADKYEINEPVVNRLNRLTRREDEYKSTQDYK
                     VDRDLAYRNIEKLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDI
                     DHVMIHYADKTKEIKAVHQKESKVAQVREYSIDGLDDIVYTPNMVDKNRDQLIKDIKD
                     RLATVELISPEVRALMDKRDTSRDPNANSDERKNGYIRDLYFEESFSETKANLDKLVK
                     SLIENADHQLNSDEAAMKALVKKVDENKAKIVMALTYLNRYYDIKYGDMTIKNLMMFK
                     PDFYGKSVDLLDFLIRIGSSERNIKGDRTLDAYRDMIGGTIGKSELHGFLDYNMRLFT
                     NDTDLNDWFIHAAKNVYIVEPKTTNPDFVNKRHRAFDGLNNGVHNRMILPLLTLKNAH
                     MFLISTYNTMAYSSFEKYGKYTEAEREAFKDKIKEVAHAQQTYLDFWSRLALPSVRDQ
                     LLKSQNRVPTPVWDNQNYHNVEGVNRMGYDKNNKPIAPIRELYGPTWRYHTTNWYMGA
                     MASIFQDPNNNDQVYFMGTNMISPFGISAFTHETTHVNDRMLYFGGHRHRQGTDVEAY
                     AQGMLQTPDKSGNGEYGALGLNMAYHRENDGDQWYNYDPDKLKTREDIDRYMRNYNDA
                     LMMLDHLEADAVIPKLHGNISRWFKKMDRQYRKNGELHQFDKVRELTEDEKKKIVINN
                     IDDLVNNNLMTKHGAPSDRTYNPEDFDSAYVNINIMTGIYGGNTSQGAPGAASFKHNT
                     FRMWGYFGYENGFISYASSKYQGEADKTNKKLLGDDFIIKKVSKDKFNNLEEWKKQYF
                     KDVKSKAEKGFTAIEIDGRQITNYAQLKTLFAEAVQKDIDGMSDPKIKDHFKNTVDLK
                     SKVFKALLKNTDGFFNKLFKEDI"
     gene            complement(20845..26367)
                     /locus_tag="VW348_001181"
     CDS             complement(20845..26367)
                     /locus_tag="VW348_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEU9746080.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIEIKIDFQEEI
                     QENPDLVEGIVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPIPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGVPEVQPALSKAVITDKG
                     ETEVQPESPDTVVSDKGEPKQVAPLPEYTGPQASAIVEPEQVAPLPEYTGVQAGSIVE
                     PEKVEAPKEYTGKIEQPSAEDTKPENGASSTNGESERPKDKIKEEKQVDKKLELRNVS
                     NVELYTVENNKYRHITAVDGALDSSLKYFMKVKSENFKDIMLPVTKIESTTKNNKEVY
                     KIVAHAENLIQHENNVISNDYTYYLPKTQQSETGVYTSFKNLVDAMNSDPNGTFHLGA
                     TMDAREVELPDDQESYVKNEFYGKLIGKNNGKYYAIYNLKKPLFKTLNTATIQNLSIK
                     EANVSSKEDAATISKEAKYNTLIDNVHSDGIIAGERGIGGLVSKVDNSRISNSSFTGR
                     ITNTYDTTAGYEIGGLVGKLSGSLASIEKSIASIDIASNAKSGDQIVGGIAGVVEKSA
                     TIKYSYVEGNVNNVRHFGKVGGVAGNLWDRDSQDVSKSGKLSYVLSDVNVTNGNAIAG
                     YNFNGIKTIETYSNKNNKVVNVVQEDDEVVTKDSDVQRGTVLDADKVKEKKIELVSKH
                     STKVEDFDFTSRYNTNYNEVTGYQQSREQVYKNIEKLLPFYNRETIVKYGNLVEDNSD
                     LFTKKLLSVVPMKNNEVITDINKNKQEINKLLLHFEGNKSRVLNIAYKNDFSKVAEYD
                     IANTKLMYTPNTMLHDYNNIVKTILNDLKSVQYSSADVRKVLDISGNIKLTELYLGEQ
                     FEKTKANIEDSLSKLLTADAAIVENNNKVIDNYVIEKIKNNKEALLLGLTYLERWYNF
                     NYGETNAKDLIMYHLDFFGKSNSSALDNVIELGKSGFNNLLAKNNVITYNVLLAKNYG
                     TESLFKALEGYRKVFLPTISNNEWFKKQTKAYIVEEKSTIEEGREKQGKEGTKYSIGV
                     YDRLTNPSWKYQSMVLPLLTLPEEKTVFMIANISTIGFGAYDRYRSSEYPKGEKLNKF
                     VEDNAKEAAKRFRDHYDYWYKILDNDNKEKLYRSILVYDAFKFGTDKDKDKVTHQATF
                     ETDHPAIKYFFGPAGNNVVHNGHGAYATGDAFYYMAYRMLDKDGAVTYTHEMTHNSDR
                     EIYLGGYGRRSGLGPEFYAKGLLQAPDHPYDPTITINSVLKYEDSENSTRLQVADPTQ
                     RFNSAEDLHNYMHNMFDVIYMLEYLEGKAVANLETNQKYELLRKIENKFDLDQDGNNV
                     YATNVVRRLTMDEVNKLNSFDSLIENDIITSRGYKDQEYKRNGYYTIDLFSPIYSALS
                     GEKGTPGDLMGRRIAFELLAAKGYKEGMVPYISNQYEKDAKAAGSKINSYGKEVGLVT
                     DELVLEKVFNGQYKTWTQFKKDMYKEREKQFSKLNRVNFINPNNPLSRQRNVSVTDIG
                     VLERMIVEAVRDDAQDDVAKFYPETNSRVLKLKKAIYKAYLDQTNDFRSSIFENKK"
     gene            complement(26576..27754)
                     /locus_tag="VW348_001182"
     CDS             complement(26576..27754)
                     /locus_tag="VW348_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746081.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSIC
                     VCGNVIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKNGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDYRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            complement(27969..31619)
                     /gene="addA"
                     /locus_tag="VW348_001183"
     CDS             complement(27969..31619)
                     /gene="addA"
                     /locus_tag="VW348_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEU9746082.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMVERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGCQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFCFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKPHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     HVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(31616..34891)
                     /gene="rexB"
                     /locus_tag="VW348_001184"
     CDS             complement(31616..34891)
                     /gene="rexB"
                     /locus_tag="VW348_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEU9746083.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMNFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQIALVIDGFTRFSAEEERVVDLLHGKGAEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYIDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERKNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLHPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            complement(35091..35246)
                     /locus_tag="VW348_001185"
                     /pseudo
     CDS             complement(35091..35246)
                     /locus_tag="VW348_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
BASE COUNT        10148 a         7005 c         6748 g        11466 t
ORIGIN      
        1 aatatattta aaaatatttc agaaaagata atcttcgaaa gaggtagtaa aatgcttaat
       61 gatttaaaaa gtaattataa aaaatagcca gtctttataa actgtattca cgtattcaaa
      121 tcgtatatat agtcgattta ttaaatcttt agataaactg taaaaagtgg tttccatagc
      181 cactttttgc tataatagag gcagtaaaaa tgaaggagtc ggctatggaa cactcgtctt
      241 ggcatgcttt gattaaggcg caattacctg agggttattt cgggaaaatc aatcagttta
      301 tggagcaggt ctattctcag gggattattt atccacccaa ggaaaaggtt tttcaggctc
      361 tcttgacaac actgcttgaa gaagttaagg tggtaattct agggcaagac ccctatcacg
      421 gaccaggtca agcgcagggc ttgagttttt ctgtacctga ctctatccca gctccaccat
      481 ccttgcaaaa tatcttgaaa gaattgtcag atgatatcgg agttaagaaa tctcatgatt
      541 tgacagcttg ggctgagcaa ggagtcttgc ttcttaatgc ttgtttgact gttcctgctg
      601 gacaggccaa tggtcatgct ggtcaaatct gggagccttt tactgatgct gtgattcagg
      661 tggtcaatca tctagataga ccagtcgttt ttgtactctg gggagcttat gcacgtaaga
      721 agaaggcatt agttaccaat cctcatcact tgattatcga atcagcccat ccaagtcctt
      781 tgtcggttta tagaggattt tggggttcca agcccttttc caaggccaat gcattcttaa
      841 aagagacagg acaagagcca atcgattggc ttagataagg agaaaatatg cctcagttag
      901 cgacgatttg ctacattgat aatgggaaag aactgctcat gctccatcgt aataagaaac
      961 ccaatgatgt ccatgaaggg aaatggattg gtgtgggtgg taagctagag agaggagaga
     1021 cgccccagga atgcgcggcg cgtgaaatcc ttgaagaaac agggctcaaa gccaagccag
     1081 ttctaaaagg tgtcatcact tttcctgaat ttacaccaga tttagactgg tacacctatg
     1141 tttttaaggt gacggagttt gagggcgact tgattgactg caatgagggg acgctagaat
     1201 gggttcccta tgatgaggtt ttgagcaagc cgacttggga aggtgaccac acctttgttg
     1261 agtggctttt agaggataaa cccttctttt cagccaagtt tgtttatgat ggggataaat
     1321 tgttggatac ccaagttgat ttctatgaat aaaggagaaa gcagatgcta ctaatcaaaa
     1381 atggtcgtgt aatggatccc aagtctggtt tggatcaagt ttgtgatgtc ttagttcaag
     1441 atgggaaaat tatcaaaatt gcgtctgaga tcacggaaga aggagcagaa acgattgatg
     1501 ctactggtct tgtggttgct cctggcttgg tcgatattca tgttcatttc cgtgaacctg
     1561 gtcaaacaca taaagaagac attcatactg gtgccctagc agccgctgca ggtggtttta
     1621 ctactgtcgt catgatggct aataccagtc caaccatttc agacgtggag actttgcaag
     1681 cagttctcca gtcagctgcc aaagagaaga ttaatgtcaa gacagttgcg accattacta
     1741 aaaactttaa tggtaaaaac ttgactgact ttaaggcact cttagaagct ggtgcggttg
     1801 gtttctctga tgacggtatt ccgcttgaga gcagtaagat tgtcaaggaa gccatggagg
     1861 aagccaaaaa actcaatacc tttatcagcc ttcatgagga agatccaggt ttgaacggtg
     1921 ttcttggctt taatgaaaat attgctagag aacatttcca tatctgcggt gctactgggg
     1981 tggctgagta cgctatgatg gcgcgtgatg tcatgattgc ctatgcaact aaagcccatg
     2041 ttcacatcca gcatttgtct aaggaagaaa gtgttaaagt agtggagttt gctcaggggt
     2101 taggtgcaga agtcacagca gaagtagcgc cacagcattt ctctaagaca gaagcacttc
     2161 ttttaacaca aggtagcaat gctaagatga atccaccgct tcgtttggaa tcagaccgtc
     2221 gtgccgttat cgaaggtctc aaatcaggtg tcatcacagt tattgcgact gaccacgcgc
     2281 ctcatcatgt agatgaaaaa aatgttgagg atattaccaa agcgccatct ggtatgactg
     2341 gcttagaaac atccctgtct ctcagcttga cctatttagt agaagctggt gagttgagct
     2401 tgatggaatt acttgaaaaa atgacataca acccagccaa gctttacaac tttgaagcag
     2461 gttacttggc tgagaatggt ccagcagata tcactatttt tgatgccaag gctgaccgct
     2521 ttgtggactc ccattttgct tccaaagcag ctaattcacc attcatcggt gaaaccttaa
     2581 aagggcaggt taaatatacc atctgtaagg gacaaatcgt ctatcaagct tgataggagt
     2641 tagaatatga attattttcg aaaacgtagg gagagacaag cgaaatctaa tagtggaatt
     2701 tactgtcccg cagctaatcg ttccaaaatt caatatgaaa ctaaagaaaa agctgaccat
     2761 gcggttcaat atgataacgg aggtttagtt agaagctatt attgtcgtac atgtgcgtgt
     2821 tggcatacta cttcaaaatc taataaacct ccgctaagtt tgaaaaacta tggtctgaaa
     2881 ctctttggtt tagataaatc agaatagaaa gagaagtatg tataagacaa agtgtttacg
     2941 agagaagtta gtattatttt taaaaatttt cttcccaatc ctgatctacc aatttgccaa
     3001 ttattctgcc tcttttgttg atactgcaat gacaggtcaa tacaacacta tggacttggc
     3061 tggtgtatct atggcaacca gtatctggaa tcctttcttt acatttctaa cagggattgt
     3121 gtcagccttg gtgcctatca ttggtcacca tcttggtcga ggcaaaaagg aagaagttgc
     3181 gtctgatttt taccaattta tttatttggc cttgggccta tctgtggtct tgctggggat
     3241 ggtacttttc ttggcaccaa taatcttgaa tcatattggg ttagaagcag cagtagcggc
     3301 agtagcggtt cgctatcttt ggtttttatc tatcgggatt atccccttgt tgctctttag
     3361 cgtcattcgt tccttgctgg attcgctggg cttgaccaaa ctgtccatgt acctcatgct
     3421 tttgttactc cctctcaata gcggatttaa ctatctcttg atttacggtg cctttggtgt
     3481 tccagaactg ggaggggctg gtgctggttt aggaacatcc ttggcctact gggtcttgct
     3541 tgggatttct gttctggttt tatttaaaca ggagaagctc aaagccttac accttgagaa
     3601 acgaattcca cttaatatgg ataacattaa ggaaggagtt cgtttaggtc tgcctattgg
     3661 gggaactgtc ttcgcggaag tggctatctt ttcagtggtt ggcttgatta tggctaagtt
     3721 ttcgtccttg attatagcta gtcaccagtc agctatgaac ttttcaagtc ttatgtacgc
     3781 ctttcctatg agtatctcat cggctatggc tattgtcgtt tcctatgaag tgggagccaa
     3841 gcgatttgat gatgcgaaaa cctatattgg tctaggaaga tggactgctc tcatttttgc
     3901 ggccttcacc ctaaccttcc tttacatttt taggggaaat gtggccagtc tttatggtaa
     3961 cgacccaaaa tttatcgatt tgacagcgcg ttttttaact tatagtcttt tcttccagtt
     4021 agcagatacc tttgcggcac cgcttcaggg aattttgcgg gggtataagg atacagttat
     4081 tcctttttac cttggtttgc ttggttattg gggcgtagca atccctgtgg ctacgctatt
     4141 tgattcccta acagattttg gagcttattc ttactggatc ggcttgatta ttagtttgat
     4201 tgtgagtggg gcgctctacc gttggcgttt aactgtgatt atgaagagat ttgaatcttt
     4261 agcaaaatcc aaacgctaaa aagtttgtga aaaaatattc ttgacaagaa aatcccttgt
     4321 tttcacgggg ttttcttttt tattttgtga aatttctttt agaaaaactt tgacagtatt
     4381 tgccaaaagc ggtaaaatag taaggtaaga agaaagttag aaaggcaaga agatgtcaac
     4441 tttagataaa aatcttttgc tagaaatgtt ccgtaagatg gaagaaatcc gtcgcatgga
     4501 cttaaaaatt gcacaattag taaagaaagg gaaagtgcca ggaatgacgc acttttctgt
     4561 tggtgaagag gcagctaacg tgggggctat gttagctctc aatccagatg atctgattac
     4621 ctcaaaccac cgtggacacg ggcaagctat tgctaaaggg attgacctca acggaatgat
     4681 ggctgaaatc cttggtaaat acactggaac ctgtaaaggg aaaggtggat ctatgcatat
     4741 cgctgacctt gatgctggga accttggtgc caatggtatc gtaggtggtg gtatggggat
     4801 cgctgtcggt gcagccctca gtcagcaaat gcaaaatacc ggtaaaatcg ttgtctgctt
     4861 ctttggagat ggtgcgacca atgaaggtgt tttccacgaa gcagtgaaca tggcttctat
     4921 ctggaacctg ccagtcattt tctattgcat taacaacggt tacggtatct ctgcggatat
     4981 caagaaaatg accaatatag aacatatcca tcaacgtagc gccgcttatg gaattcctgg
     5041 aatgttcatc gaagatggta acaatgtcat cgatgtctat gaaggatttc agaaagctgt
     5101 ggaccatgtt cgcagtggca atggttcagt cttgattgaa agtgtaactt atcgctggct
     5161 cggtcactca tcatctgacc ctggtaaata tcgtacgcgt gaagaagtgg aattgtggaa
     5221 acaaaaagat ccaatcgaaa acctccgcaa ttaccttatt gaaaataaca ttgcaagtgc
     5281 cgaagaattg gaagaaatcc aagcgcaagt aaaggaagca gtagaagctt ctgttaaatt
     5341 tgcagaggaa agcccattcc caccgcttga atcagccttt gaagatattt acgcagacta
     5401 aggagaaaga gataaaatgg aaacaaaaac aatgtccttc cgtgacacca ttatccttgc
     5461 tatgtctgag gaaatgcgtc gcgatgaaaa tgtgttcttg atgggagaag atgtcggtgt
     5521 cttcggagga gacttcggta cttctgttgg aatgcttgaa gaatttggtc cagaacgtgt
     5581 ccgtgactgt ccgatttctg aagctgccat ctctggagca gcagcaggag cagccatgac
     5641 aggacttcgt ccaatcgtcg atatgacctt catggacttc tctgttattg ccatggacaa
     5701 tatcgtcaac caagctgcta aaacacgtta catgtttggt ggtaaaggtc aggttccaat
     5761 gactgttcgt tgtgcagctg gtaacggagt tggctctgcc gcccagcact cacaatctct
     5821 agagtcttgg tttactcaca ttccaggact taaggttgtg gcacctggaa cacctgcgga
     5881 catgaaaggc ctgcttaagt cttctatccg tgataacaac ccagttatta tacttgagta
     5941 caagtcagaa tttaaccaaa aaggggaagt gccagttgat ccagactaca caattccact
     6001 tggggttggt gaaatcaaac gccaaggaac ggatgtaaca gttgttactt atggaaaaat
     6061 gcttcgccgt gtggttcaag ctgctgaaga attagcagaa gaagaaattt cagttgaaat
     6121 tgttgaccca cgtacccttg ttccgcttga taaggatatc atcataaact cagtgaagaa
     6181 gactggtaag gttattctgg tcaacgatgc ccacaaaaca agtggctata tcggtgaaat
     6241 ttcagctatt atttcagaat cagaagcatt tgactatcta gatgcaccaa tacgccgttg
     6301 ttcaggagaa gatgtgccga tgccttatgc acaaaaccta gaaaatgcaa tgattccaac
     6361 agttgaaagt atcaaagatg caatccgaaa aacttataac aaagactaga gttacataat
     6421 ataagttatg taactaaaat aaagctgacg agaaactttg tatcttttag gtgcagagct
     6481 cttcgtcatt aatatcttat attcgagcac gggctaaaag ctcggaaaaa agataaatct
     6541 ccttggcttc atcgaagcca tcgtcgattt cctatttttc agtcgctttt gacgcccttt
     6601 gtatcataaa tagaattgga gaggtcatgg ctgatgacaa gctaagagcg actcctgcag
     6661 ctagaaagtt agcggatgat ttagggataa acctctacga cgtttctggc tcaggtgcaa
     6721 acggtcgtgt ccacaaagaa gacgtggaaa cttataaaga cacaaacgtg gttcgcattt
     6781 cgccacttgc aaaacgaatt gccctcgaac ataacattgc ttggcaggaa atccaaggaa
     6841 ccggtcatcg tggtaaaatc atgaagaagg atgttttggc cctgcttcct gaaaatatcg
     6901 aaaacgatag catcaaatct cctgctcaga ttgaaaaagt ggaagaagtc cctgataacg
     6961 taacaccata tggtgaaatc gagcgtattc caatgacacc aatgcgtaag gttattgccc
     7021 aacgcatggt tgaatcttac ttgactgcgc caaccttcac cctcaactat gaagttgata
     7081 tgactgaaat gttggctctt cgtaagaagg ttcttgagcc aatcatggaa gcaactggga
     7141 agaagactac tgtaacagac cttctttcgc ttgcagttgt taagactctt atgaaacacc
     7201 catacatcaa cgcttcattg acagaagatg gcaagactat tatcactcac aactatgtca
     7261 atcttgccat ggcagttggg atggataatg gattgatgac acctgttgtt tacaatgctg
     7321 agaagatgag tctttcagaa ctggtggtag cctttaagga tgttattggc cgtaccttgg
     7381 atggtaaatt ggctccaagt gagttacaaa attcaacatt cacaatcagt aatttgggaa
     7441 tgtttggtgt tcagtccttt ggtccgatta ttaaccaacc caactcagct atccttggtg
     7501 tcagttcgac aatcgagaag ccagttgtcg tcaatggtga aattgtgatt cgcccaatca
     7561 tgagtttagg attaaccatt gaccaccgtg tcgtagatgg tatggctggt gctaagttta
     7621 tgaaggactt gaaagagttg attgaaacgc caatctcaat gttaatttaa gagcaagagt
     7681 attcattttt aagatataga taaaggaagg aagacatggc cttagaaata attatgccaa
     7741 aagccggcgt ggatatgaca gaaggacaaa tcgtccaatg gaataaaaaa gtcggagaat
     7801 ttgtaaaaga aggagaaatc cttttggaaa tcatgactga taaagtcagc atggaattgg
     7861 aagccgaaga agatgggtac ttgattgcca ttctcaaagg agatggtgaa actgtccctg
     7921 taacggaagt tatcggttac cttggtgaag aaagggaaaa catcccaaca gctggagcag
     7981 catcgccaga agctagccct gtacctgtag caagtacctc aaacgatgat ggtaagagcg
     8041 atgatgcttt tgatatcgtt gtgattggtg gaggtcctgc tggttatgtt gcagccatta
     8101 aagctgccca actcggcggt aaggttgccc ttgttgagaa atctgaactt ggtggaacct
     8161 gcttaaaccg tggatgtatt ccaaccaaga cctaccttca tagcgctgaa attattgaaa
     8221 atatcggtca tgctgcaaat cgtggtatcg tgattgaaaa tcctaacttc actgttgata
     8281 tggaaaaact tttagaaact aaatctaaag ttgttaatac tcttgttggt ggtgttgcag
     8341 gacttcttcg tagctacgga gttgctgttc ataaaggaat tggtacaatc actaaagaca
     8401 agaacgtctt ggtaaatggt tctgaattgc ttgaaaccaa gaaaatcatt cttgctggtg
     8461 gttcaaaagt cagcaagatc aacgtccctg gtatggaatc tccacttgtc atgactagtg
     8521 atgacattct tgaaatgaac gaagtgccag aaagccttgt tatcatcggt ggtggagttg
     8581 tcggtatcga actcggtcag gccttcatga catttggttc aaaagtgact gttatcgaaa
     8641 tgatggaccg tatagttcca gctatggatg tggaagtttc taagaacctt cgcttgatcc
     8701 ttgagcgtaa aggaatgacc atcttgactg gtactaaact gcaagaaatc attgaggaaa
     8761 atggtcaact tcgtatcaag gttgaaggaa aagacgatat catcgcaagc aaagctcttc
     8821 tttcaattgg tcgtatgcca gaccttgaag gtattggaga ggttgagttt gaattggatc
     8881 gtggttgtat caaggtcaac gaatacatgg aaacttcagt tccaggcatt tatgcaccag
     8941 gtgacatcaa cggtactaag atgttggctc acgcagcttt ccgcatgggt gaagtttccg
     9001 ctgaaaatgc ccttaaagga aatcatgcag ttgccaaatt gaatttgact cctgcagcca
     9061 tctacactct tcctgaagta gcagcagtag gtttgacaga agaacaagcc cgtgagaaat
     9121 acgatgttgc catcggtaag tttaactttg ctgctaacgg tcgtgctatt gcatctgacg
     9181 cagctcaagg tttcgtaaaa gttatcgctg ataagaaata cggagaaatc cttggtgtac
     9241 acattattgg tcctgcagcc gcagaattaa taaacgaagc atcaagcatc atcgaaatgg
     9301 aaatcactgt tgaggaaatg ctgaagacca tccacgggca cccaacttac tctgaagtga
     9361 tgtacgaagc gtttgcagat gttctaggaa tggccatcca ttcacctaag aaaaaataaa
     9421 acgaagatag attagactgg aaggttattt ccagtttcta tcatataaag taaagggata
     9481 tcatgaaata cattatcaat cattcaaatg acactgcttt taatattgcc ttggaagaat
     9541 acgcctttaa acaccttttg gatgaggatc aaatcttcct actttggatt aacaagccat
     9601 ctatcattgt tggtcgtcac cagaacacta ttgaagaaat caaccgtgat tatgttcgcg
     9661 aaaatggtat tgaggtagtt cgccgtatta gtggtggtgg agctgtttac cacgatttaa
     9721 ataacctcaa ctacacgatc atctccaaag aagatgaaaa taaggcattt gacttcaaga
     9781 gcttctcaac tccggttatc aataccttgg ctcaactcgg ggttaaagct gagttcacag
     9841 gtcgtaatga ccttgagatt gatggtaaga agttctgtgg caatgcccaa gcctatatca
     9901 acggccgtat catgcaccac ggttgcttgc tctttgacgt tgatttgtca gtcctcgcaa
     9961 atgcccttaa ggtttcaaaa gataaatttg aatcaaaagg tgtgaaatcc gtccgtgccc
    10021 gtgtaaccaa tattatcaat gaattaccaa aaaaaatcac agtcgaaaaa ttccgtgatt
    10081 tactcttgga atacatgaaa aaagagtacc cagagatgac tgaatacgtc ttttcagaag
    10141 aagaattggc cgaaatcaat cgcatcaagg atactaagtt tggaacttgg gactggaact
    10201 atggtaaatc acctgaattt aacgtccgtc gtggaaccaa attcactagt ggtaaggttg
    10261 aagtctttgc taacgttact gaatcaaaaa tccaagacat caagatttat ggtgacttct
    10321 ttggtattga agacgttgct gcagtagaag ctgtccttcg tggggtgaaa tacgaacgcg
    10381 aagatgttct taaggcgcta aaaaccattg atatcacacg ctacttcgct ggtattagcc
    10441 gtgaagaaat cgctgaagcg gtagttggat aaatcaaaaa gaagttggcc aactaaccaa
    10501 cttctttttt tgatatttat ttacataatt taaaatacgt aaaatcataa actatccaga
    10561 gcattctttt gttcatcact aacaatatgg gtatagaggt cagtgacttg tgtgctagca
    10621 tgtcctagtt ggtgactgac taaaacttgt gatttagtcg catcatagag cctagttgct
    10681 agtgtatggc gcagtttatg gggtgttaca cgcactttaa aatcctctga gtatttagca
    10741 accattttct caacgctaga agcatcgata cgattaggaa cacctctgta gagagttaaa
    10801 aaaagggctg tatctgtttt ttccgtttta tagcgttgat tccgaatggc cagataattc
    10861 tctaaataag gtttagcaaa agcagcgaca ttgactgagt cacgtttgcc accttttcga
    10921 gtaacatcaa taaccatcat ttttagattg agatctctta gatctagatt aacagcttca
    10981 gataagcgaa caccagatgc caagagaagg gcaataatgg ctaaatctcg ttctttattt
    11041 ttgttgaatg atgagagagc tcgatttgaa agctgttgtg ggtgctcttg atcgatataa
    11101 gttagaaaac cttctgtttc atcacctaga aagagttttt gcttgatatt ttcagctctg
    11161 gcagcaaggg tttctttctt tttcttggtt gaaacttttt tcattacatt acgatagaaa
    11221 taaggttccc cctgatcgtt ttcaacctcc tcggttagat acttgtaaag actagaaagt
    11281 gctgataagg ttcgattgat agttgtctgt gaaacacctt gttttgttgt attagcattc
    11341 agcaagggac gttcacgtag ataaaggata aaggattcca tgtctttctt agacatattt
    11401 tccaaaactg ataaaggaat atcggatatt ttatcagcgt ttgaaatacc agactccaaa
    11461 acccagctga aaaatcggtc atattcctta aggtattcgt acagggttgt aaaactgtag
    11521 ggcacagcca gtttagattg gtagtattcc agaacatacc agggcatgag ttgttttagt
    11581 ttgtcgattc gttccagtaa aatctcacgt ttcatgtatt ttctccataa ttaagtatac
    11641 tagtagtata gcatagactt gtacattttt caagaaaatt atagtttttc agaaagatgt
    11701 tataggagtt tttcaaagtg ataaaaagac ttagacctac aaacaaaaca gaataaggaa
    11761 aataataaaa atctcaccca ctaaacttct gttaatacta catagctaga aattggtttg
    11821 attgtcctga ttgttttatc ctatttctat ttcatttcac tatataattg ctattgtttt
    11881 ctttttcatg attttaatct tactgtacag atttgataca gtaaactcct ttctagcttt
    11941 atactttatc atttctaact taattatagt cttattttta ataaagttca attatttata
    12001 tgtaaaattc ctcatcagta aaaaataacc gatctcattt ctgagaatcg gttttctaaa
    12061 taaatcaagc cgaataaatc aagccgatca tttacataac ataaattatg taaatgatcg
    12121 tactacaaca acaaatcttt gacttttcca atttcacttt ttggaataac caggtgaatc
    12181 atatcaccca gatacattct ggttgagccg ttaactgttt ggctcttgcc attatggact
    12241 tgagttgtga tgaggacgtt gtgtggtaag ttgagttcat gaacttgttt cccagcaatt
    12301 ttatcagaaa ctggtatttc gataagtgta acttctcctt cgctagatac ttcttctgga
    12361 agcatttttt ccagcatggc ttcatagact ggcgtacctt tgagcaaatc catgataata
    12421 taagaaacaa gagtgacaag accaagtggc atgaggttgc gaatatctcc taccatctca
    12481 gttacgagga tcatagcagt taagggagct tttgatatgg ctccaaaata gccactcatt
    12541 cctagaatga caaatatagg gaattgctct tgactgacaa gtccaagatt gacacagata
    12601 acaccaacta aggcaccaag caaagaacca agagctaaaa tggggaggaa aattcctcct
    12661 ggcagtccac ttccatagct aatcatactc caaataaagc ggattaaaaa gtaagctaat
    12721 aaaacttgga aactaaaatt ttgttcagtt aaagaaagga caagctgatt tccgccacca
    12781 atgatttgag gtaagaagat tccgactggt atgataagga taaaagccaa gatgggataa
    12841 taagccctat ccaaatggat tttttgacca atcaagtcat aaactcttcc aacgtttaat
    12901 acagctttct catagagaaa acctgaaaat ccaaggaaaa ttcccatgac gagatatatc
    12961 caatactgat ctagggtcat gggaggaatg ttatctggca tatccaatac tggtgtcaaa
    13021 ccgaacatga gtagagacac aaagtttgct acgatgctgg ctgctagagt tgagacccag
    13081 aaaaagcgcg aaaaatggtg atagacttct tctacaacaa agagaagtgc tgcaatagga
    13141 gcattaaagg ctgcggctaa acctgctgca gctccactgg caatcaagga acgttcctct
    13201 actggactgg atttgagcca cttggcaatt cctttaccac caactgctcc aagttgaatg
    13261 ctgggtccct ctcgacccag catgagtcca ctggcaatag caagaatacc tagcacatat
    13321 tttttccaaa gaatgcccca ccagttgagg gacatgaggc ctttcagttc ggcttcgact
    13381 tgaggaattc ctgagccttt aatatctttt tctgaccgtg ttagtttggc actgagccaa
    13441 cagatgagta tataaaacaa aaccagtaca aaaagattgc gcactaagta cccttgatct
    13501 tgataaactc cttgtatcag gtggaagccc ttttcaatta agaaacgaaa ggatccgacg
    13561 ataattccaa cgatgaggcc gacaatgatt cctcgaccaa cttgggatag tatagtgctg
    13621 gatgcaaagg cgaattcttt cttagaacgg actatttccg actgttcctc catggtattt
    13681 cctttcaatt aattttcttt tttacctaaa accagtgatt taacgggttc aaagctggtt
    13741 cggtgaattg gggtaactcc tagttttgtg aggccttcca gatgtttagc tgtgccatat
    13801 cctgcattag tagcgaaatc atagccaggg aactgctgat cgtattcctt catcaattca
    13861 tcacgtgtta ccttggctac tatagatgct gctgcgatag agagggagtt ggcatctcct
    13921 ttgataatgg aggtttgtga aatgggcaag tccagtttca tggcatcaat caaaaggtgc
    13981 tctggttgag ggctgagctg ggagattgct tcttgcatgg ctagtttggt tgcttcatag
    14041 atgttgactt ggtcgatgac ctgattatct atgataccaa ttccaatcga caaggcttgg
    14101 tcttgaacgg cttggaaaat ctccagatgt ttctttttag gaattttctt gctgtcgttg
    14161 agacctttaa tcttacaatt tttaggtaaa atgacggccg cagcgactac aggaccagca
    14221 agaggaccac gaccaacctc atcaatacct acaattaagg tcaatccttg cttataaagt
    14281 tctttttcat aagaaagcat ggattccaag cgcaaatttt catctaattc agcttgaatg
    14341 gctcttttac gcttgctgat ttccttttga actcctgagc gattatcctt ttcaagctct
    14401 aaaaaaatag ggctttctaa ctccttgact gtcacaagga gttctttgat ttctttaatc
    14461 gttgccatcg aggtcttcca atgtatctaa ggtatagtta ccgagtttgc catcacggac
    14521 ttccttcacg aagagactgt aaaaacggtc atagtcatca cggaaaccga gggcgcgggt
    14581 catatccata ataatcacag gcgcttcttc ttcaattttc atttgtttga agcgttcagc
    14641 cagcttttct ggataatgtt ctttgaaata attgatacca aaaatggtaa cctcatccat
    14701 aggaagcaac tgatccttga tagctccagt caatgccaac ttaagtgcaa cagtttcatc
    14761 ctcaaactta ggccagagaa tccccggtgt atccaagatt tccagatctt tattggtttt
    14821 aagccattgt tgaccttttg tgacccctgg cttgtttcca acaacagcaa tctttttacc
    14881 agccaaacgg ttcatcagag tggatttacc agcgtttgga atcccgataa tcatggtacg
    14941 caaggtttca atctgaatcc cacgttcttt ctggcgagca atcttatcag ccatgagctt
    15001 cttggccgca tctgttacaa cttttacagt cacttgctct ttggagttga tagctagcgt
    15061 ctggatttct tgtgattcaa aatactgaca ccattccttg gtcattgctg gatcagccaa
    15121 gtcggccttg tttaaaatca agagttttgg tttatcacca acaatcttgg tcaacatagg
    15181 attttgacta gatagaggca agcgtgcatc tactaaaatc gtcacaaaat caacaaattt
    15241 taaattttcc tgcacctgtc gacgcgcttt agacatgtga ccaggaaacc attgaatagt
    15301 agccattgag ttttttcctt tcgtagctct gaagctgtta atctagaact aagagatctc
    15361 aatctaaaaa tgaatgatgt ccaaacagtt cttgttttat gatataaaaa tctactttat
    15421 attatatcat gccttcttta ttttgtccga tgatagcctt ttaccctatc ttttacccta
    15481 tatagaaaaa agccatcaaa tgatgacttt tcagagggag caaaaaactg tcctctttat
    15541 attttaaaca tttaaatgtc ttctttaaac agtttattaa agaaaccgtc tgtgttttta
    15601 agaagggctt tgaatacttt ggatttcaag tctactgtat ttttgaaatg atctttaatt
    15661 ttcggatctg acataccatc aatatctttt tgaacagctt cagcaaataa agttttcaac
    15721 tgagcataat ttgtaatttg acgaccatca atttcaatag cagtaaatcc tttttctgct
    15781 tttgacttaa catctttgaa gtattgtttc ttccactctt caagattatt gaatttatcc
    15841 ttagatactt tcttgataat gaaatcatca cccaataatt ttttattggt tttgtcagct
    15901 tcgccttgat atttgctaga tgcataacta atgaatccat tttcataacc aaaatagccc
    15961 cacatacgga aagtattatg cttgaatgat gcagctccag gtgctccttg gctagtatta
    16021 ccaccataga taccggtcat tatattaata tttacgtaag cactatcaaa atcttctgga
    16081 ttatatgttc tgtcactagg agcgccatgt tttgtcatca aattattgtt gactaaatca
    16141 tcaatgttgt tgataacaat tttcttcttc tcatcttcag ttaattcacg aactttatca
    16201 aattgatgta gctctccatt tttgcgatat tgtctatcca ttttcttgaa ccatcgacta
    16261 atattaccat gtaatttagg gataacagca tcagcctcaa gatggtctaa catcataaga
    16321 gcatcattat aatttctcat ataacggtcg atatcttcac gagttttcaa tttatctgga
    16381 tcataattat accattggtc accgtcattt tcacgatgat aagccatgtt aagaccaaga
    16441 gcaccatatt caccgttacc agatttatca ggtgtctgca acataccttg cgcataggct
    16501 tcaacgtctg taccttgacg gtgtctatgc ccaccgaagt aaagcattct atcgtttacg
    16561 tgtgttgttt cgtgagtaaa ggctgaaata ccaaacggac taatcatatt tgttcccatg
    16621 aaataaactt ggtcattatt attgggatct tggaaaatag atgccatagc tcccatgtac
    16681 caatttgtag tatgataacg ccaagtaggt ccatataatt cacgaatagg tgcaattggt
    16741 ttattattct tatcataacc catacgattt acaccttcga cgttatgata gttttggtta
    16801 tcccaaacag gtgttggaac cctattttga ctcttgagta attggtcacg tacgcttggc
    16861 aatgctaaac gcgaccagaa gtcaagataa gtttgttgtg cgtgagcaac ttctttaatt
    16921 ttatctttaa atgcttctcg ttcagcttct gtatacttac catatttttc aaaagagcta
    16981 taagccattg tattgtaagt cgaaatcaag aacatatgtg cattcttaag agttaataga
    17041 ggtaggatca tacgattatg aacaccatta ttcaaaccat caaatgcacg atgtcgttta
    17101 ttaacaaaat ctgggttcgt tgttttaggc tccacaatgt atacgttctt agccgcatgg
    17161 ataaaccaat catttaaatc agtatcgtta gtgaagagac gcatgttgta atctaagaag
    17221 ccatgtaatt cagacttacc aatagttcca ccaatcatat cacgataagc atccaaagtt
    17281 ctgtcaccct tgatatttcg ctcacttgat ccaattcgaa tcaagaagtc aagaaggtca
    17341 actgacttac catagaaatc aggtttaaac atcatcaagt ttttgatagt catatcccca
    17401 tactttatat catagtaacg attaaggtaa gtaagagcca tcacgatttt agctttattt
    17461 tcatccacct tcttaacaag tgctttcata gctgcttcgt cactatttaa ttgatggtca
    17521 gcattttcaa tcaaagattt gaccaattta tcaagattag ctttcgtttc agaaaaactt
    17581 tcttcgaaat aaaggtctcg gatataacca ttcttacgct catccgaatt agcattagga
    17641 tctctagatg tatctcgttt atccatcaaa gcacggactt cgggagaaat taattcaaca
    17701 gttgctaacc tatctttaat gtctttaatc aattgatcac gatttttatc aaccatgttt
    17761 ggtgtataaa caatgtcatc taatccatcg atactatact cacgaacttg cgctacttta
    17821 gactcttttt gatgaacagc tttgatttct ttagtcttat ctgcatagtg aatcatcaca
    17881 tgatcaatat ctgataaatc ggtcacgaat tgaccatcct tcatacccgt aacagaaagg
    17941 acttctttct tagctaagtt tgaatcttct gcaagtttgt taccttgatt gacaatccat
    18001 tctttgttat aaaatggttg cagtttctca atattacgat aagccagatc tcgatctact
    18061 ttatagtctt gggttgactt atattcatct tctcttctgg ttaaacgatt taagcgattg
    18121 accacaggtt cattgatttc gtatttatct gcggtaattc ctgtagcttc aattttagat
    18181 tttgcctctt cctcagaaat aggtctgata cgatttttat cttttgaacg ctggtagcta
    18241 gaatgcccat cactaacacc tattacaaca taatttcgtc ttacattatc tcctgtccag
    18301 tagccatcat cataatcaat atcactagaa ccatagaaaa tttcaccatt aggtaccttc
    18361 atcatggaaa ctgaatcttc gacagaaccg tggtgcttca tgcttcctac aacaccacca
    18421 ctttcaatcg cctcagttac ttgaattgtt cccttagcaa tagatttttt gattgctcct
    18481 tcctgacgaa cagtattgtt atttccttca ttttgtgtcc aataagcaat gcccgcagcc
    18541 ttggctttct tgccaataag atttgcgtta acatacgcgc gttcgacgag tcctttccag
    18601 ttctcaccaa cgataccagt caagaattgt ccaccatcgc cgacagaagt tacgttaccg
    18661 ataaaggcca catttctgag tgtaccttgg ttatcaatct tatcaataaa tccagatacc
    18721 caatctttac ctactatatt acctttaacc ttaacatttt caatggtagt tccaccttta
    18781 ataatattcg ctacagctgc aacttggttc gcccatggca tatttatgtc aacattacca
    18841 agattaatat tcttaatcgt tccaccaata acattgccaa ataacggacg tgacaagtta
    18901 tgaatggtat agtgattatc accatcactc aagagcttac ctttgaaatc tttcgtaaca
    18961 tatgatttac caaatgctga tacatttgtg gcattaaggt cagcacccaa tttaaactcg
    19021 tcatttggat gttcttgcat atctctcaca agttcattga aattgtaata tacattattg
    19081 acttttggaa ctggtttttc aatgtaatga atgtattcat ttctagtctt agatggatcg
    19141 acatgttgaa ttaaatcttg agcgcttgct gtaattttat aaagttcttt ttctttttca
    19201 gttactaact caatcttatc aactgctaaa cgagttactt tattatcacg actagtgatt
    19261 tttaagtaca ttttcttcac atcttcatca gaaggttttt cgctcatgaa atcactaggt
    19321 atttcagtac catcatcatt taccttcact aaattagtag atgaaatatt tttaatttcg
    19381 acctttttca actccaaacg caaagttttt tcatccagtt tagacgtttc agaaccttga
    19441 ccacgatcat aaatcattgt tgttgcaatc ttataatctt taaacaaatc caaattttgt
    19501 acagcgtcag ttaatttttc tttagataaa tcaacctttt taactactgt atcaccatct
    19561 ttaatttcag ctataatact tgatatttca gcattatctt tattatcaag ctcataattt
    19621 aagttggcag aacgattcat agcatcttct gttactttgg tcaaggtcaa aacgggaact
    19681 gttttttctt ttggattttc ttttgtacct tttacaagaa ttttaggttt catttctttc
    19741 aaaattgtta ccgtttcaac tggttcacta atttttttgc catgtaactc ttcatagcta
    19801 gtaacaattt gacgttcgcc atcctcacca acttctttaa cagaatcatc gcctataaat
    19861 ttgctaggat cagattcttc tatagtggtt ttaggaatag tctctgtacg aatatcggta
    19921 tgtaaagaag gcaactcttc tctttctgat gcaacttctg aaactgtaga tattggttca
    19981 gtatactctg gaatgtcgtt aacaggtggt tcaatcaagt ttccattttc atccactcct
    20041 gttgtaccta ctggttcagt gtatgctagt ttctcatgaa cttcaggctc aacaaggttt
    20101 gcacctattg gttgcgtata gtcaggcttc tcatgaactt ctggttcgcc tttgtcagtc
    20161 acaacagctt ctggtaatgt cggttgtact tccggttcgc ctttgtcagt cacaacagct
    20221 tcgggtaagg ctggttgaac ctccggttcc cctttctctg ttacaacttt gggttgctca
    20281 actggcgaaa cagttgatgc tggagaaacc gacgaaacag ttttatcatc aagctccaag
    20341 taaccaacat atctgtaacc agaaatttgc aacacaccat cacgtccaga ctcatggatg
    20401 ttagcattca aattaagtgc tgaagcagtt gatagtgtaa ctaaacctgt cgcccctaca
    20461 atcaaaaatg tagctatttt tttatttcta ttatcttttg tgataatcac aataagactc
    20521 ccgatagcta acaaacccaa tgcagtcata atagattgag aactgcctgt gtttggtagt
    20581 gcgtcttttt cataatccaa agcatatgac tctttggatt catcaggtct accttgtttg
    20641 agttgatcac gttcagtttg tgtcaaacta ctataatcta agtaatgata agtcgatgca
    20701 ccaataactg acggtgcaaa taaaagactc cccaagaata ccgaaccaac aatacccttt
    20761 attttccgaa tggaaaattt atcttttttt aataatgaca attctaatcc tccacattca
    20821 ctttttattt cctaatagta aacactattt tttattctca aaaattgaac ttctaaaatc
    20881 atttgtttgg tcaagataag ctttatatat tgcttttttc agtttaagaa ctctactatt
    20941 tgtttctggg taaaattttg ctacgtcatc ttgcgcatca tctctcactg cttcgacaat
    21001 cattctctct agtacaccta tatccgtaac cgatacattt cgttgacgac tcaatggatt
    21061 attaggatta ataaagttaa ctctatttag tttactgaat tgtttttctc tttccttata
    21121 catatccttc ttgaattgtg tccaagtttt atattgacca ttaaatactt tttcaagtac
    21181 taattcatct gtaactaaac ctacttcttt accataagaa ttaatcttac ttcccgccgc
    21241 ttttgcatct ttttcatatt gatttgagat ataaggtacc atgccctctt tatatccttt
    21301 tgcagctaat aattcgaatg ctatacggcg tcccattaaa tcaccaggag tccctttctc
    21361 tccactaaga gctgaataaa tcggtgaaaa taaatcaatt gtataataac catttctctt
    21421 atattcttgg tctttgtacc ctctgctagt aataatatca ttttcaatta aactatcaaa
    21481 agaatttaat ttattaactt catccatcgt taatctgcga acaacatttg tcgcgtatac
    21541 attattaccg tcttgatcaa gatcaaattt attttcaatt tttcttagta actcatattt
    21601 ttgatttgtt tctaaattag ctacagcttt tccttctaaa tattctaaca tataaattac
    21661 atcaaacata ttatgcatat aattatgtag gtcttctgca ctattaaatc gttgagttgg
    21721 atcagctact tgaagtcttg ttgaattttc tgaatcctca tatttcaaga cagagttaat
    21781 tgttattgtt ggatcatatg gatgatccgg agcttgtaat aatccttttg cataaaactc
    21841 aggtcctaat ccgcttcttc ttccatatcc tccaagataa atctctctat ctgagttatg
    21901 tgtcatttca tgagtatatg ttacagctcc atctttatcc aacatacgat atgccatata
    21961 atagaatgca tctccggtag catatgctcc gtgtccatta tgaacaacat tatttcccgc
    22021 aggtccaaag aagtatttta tagctggatg atcagtttca aaagtagctt gatgagttac
    22081 tttgtcttta tctttgtcag taccaaattt gaaagcatca tatactagaa tacttctata
    22141 taatttttct ttattatcgt tatctaatat cttataccaa taatcataat gatctctaaa
    22201 tcgtttagcc gcttctttgg cgttatcttc tacaaatttg tttaactttt ctcccttagg
    22261 atattctgaa cttctatatc tgtcataggc tccaaatcca atagtagaaa tattcgctat
    22321 cataaacact gttttttctt caggtaaagt taatagtggt aagaccatac tttgatattt
    22381 ccaagatgga ttagttaatc tatcatatac cccaatagaa tatttagttc cctcttttcc
    22441 ttgtttttct cttccctctt caattgtaga tttttcttct acaatatatg cttttgtttg
    22501 ttttttaaac cactcattgt tagaaattgt tggtaagaat acttttctat atccttctaa
    22561 tgctttaaat aaactttcag ttccataatt tttcgctaat aatacattat aagtaattac
    22621 attatttttt gctaataaat tgttaaatcc agatttacct aactcaataa cattatctaa
    22681 tgcagaacta tttgatttac caaagaaatc caagtggtac attattaaat ctttagcatt
    22741 ggtttctcca taattaaaat tataccagcg ttctaaatac gttaatccta acaataaggc
    22801 ttccttatta ttttttattt tctcaattac ataattatct attaccttat tgttattttc
    22861 cactattgca gcatctgcag taagtagttt tgataaactg tcttctatat ttgcttttgt
    22921 tttttcaaat tgttcaccta aatataactc tgttaatttt atattaccag aaatatctaa
    22981 tacttttcta acgtcagctg aactatattg aacagatttc agatcattta aaatagtttt
    23041 tacaatatta ttataatcat gcagcattgt attaggtgta tacattaatt ttgtattagc
    23101 tatatcatac tcagcaactt tagagaaatc attcttatat gcaatattta atactcgtga
    23161 tttgttacct tcaaaatgta ataacaattt gtttatttct tgtttatttt tattaatatc
    23221 agttattact tcattgttct tcataggaac aactgataga agttttttag taaataagtc
    23281 actgttatcc tctactaaat taccatactt aactattgtt tctctgttat agaaaggaag
    23341 taatttttca atatttttat atacttgttc tctcgactgt tggtaacctg ttacttcatt
    23401 gtaattagta ttgtatcttg aagtaaaatc aaaatcttct actttagtgc tgtgtttaga
    23461 aaccaattct atctttttct cttttacttt atcagcatct aataccgtac ctctttgtac
    23521 atctgaatct ttagtcacaa cctcatcatc ttcttgtact acgtttacta ccttattatt
    23581 tttattgcta tatgtttcaa tcgtttttat tccattgaaa ttatagccag ctatagcatt
    23641 accattcgta acattgacat cacttaaaac atatgatagt ttacctgatt tacttacatc
    23701 ttgtgaatct ctatcccaaa gattacctgc aactccccca actttaccaa agtgtcgcac
    23761 attgttaaca tttccttcaa catagctata cttaattgtc gcacttttct caacaactcc
    23821 ggctatacca ccaacaattt gatctcctga ttttgcatta gaggctatgt caatcgatgc
    23881 tattgatttc tctatagaag caagcgaacc agaaagttta cctactaaac caccaatttc
    23941 ataccctgca gttgtatcat atgtgttagt tattctgcct gtaaaactac tattagaaat
    24001 tctcgagtta tctacttttg aaaccaatcc accaattcca cgttcaccag ctataatacc
    24061 atcagaatga acattatcta taagagtatt gtattttgct tctttcgata ttgtagcagc
    24121 atcttcttta gaagaaacat tcgcttcttt tattgaaaga ttctgaatag tagcggtgtt
    24181 tagagtttta aataaaggtt ttttcaagtt ataaatagca taatacttac cattattttt
    24241 acctattaat tttccgtaaa attcattttt tacataactt tcttgatcat ccggaagttc
    24301 aacttcacga gcatccatag ttgcacctaa atggaatgtt ccattagggt cactattcat
    24361 tgcatcaact aaatttttaa atgatgtata gacgccagtt tcactttgct gagtttttgg
    24421 taaataatat gtatagtcat tcgaaataac attgttttcg tgttgaatta gattttctgc
    24481 atgagccaca attttgtata cttctttatt gttttttgtt gtactttcaa ttttagtaac
    24541 aggcaacatt atatctttaa aattttctga ttttaccttc atgaaatact tcaatgaact
    24601 atctaaagca ccatctacag ccgtaatatg tcgatattta ttattttcta ccgtatataa
    24661 ttccacgttt gaaacatttc taagttctag tttcttgtcg acttgttttt cttctttaat
    24721 tttatcttta ggacgttccg attccccatt tgtagagctt gccccatttt caggtttagt
    24781 atcttctgca ctaggctgtt cgattttacc agtatattct ttcggtgctt ctactttctc
    24841 tggctcgact atcgatccgg cttgtacccc tgtgtattct ggtagtggtg ctacctgctc
    24901 tggttcaaca atagcgctgg cttgtggtcc tgtatattct ggaagcggtg ctacctgttt
    24961 aggttcacct ttatcactta ccacagtatc tggcgactct ggttgaacct cagtctcacc
    25021 tttgtcggtt ataactgctt tggacaacgc tggttgaact tctggtacgc ctttgtcact
    25081 tactacagct tcgggcaact caggctgaat tgcgggttca acaatagctc cagactgtac
    25141 gtccttatgt tctacaccag tctcaggttg ttcctttata acttgagttt ttttagtacc
    25201 tttttcgact attcttggaa taggcgcagt cgttgaagtt gaaacaattt ctcgcgaaac
    25261 ttcttccttg tttacagaga atattctgac gatttcaact ttcttaccta atttaccttc
    25321 ttgttttact cttacaattc cttcaactaa atcaggattt tcttgaattt cttcttgaaa
    25381 atctattttt atctctatag tttcctcacg atataagagt tcaggtttgt tcaattgacc
    25441 tgataaaact tcatcctgtg gatttaatgt atttacccca gtcttttctt ttggagaaat
    25501 cttctcctct ttcttcgttt ctagattctt atgttcggct aattgttctt gagaatctga
    25561 agattgtttc tcttcttttc ttggattgat taattcagta gagaaaggtt tttcaactac
    25621 ttgaacttct gtcggcttag ttgaagaaac aggtgtttgt tcctgaatag cttgtactgt
    25681 tgatggatgg tctacaaaat ttggtgtaac attataatcc accttttgtt gttttgtagg
    25741 agtggctgct gatttttctt gattacttac ttcaaaatca gaagtcgttt ttccctcttt
    25801 gatatatcca atataagtgt aacctgaaat ctctttagga agaggtaatt tttctccaga
    25861 ggtcaattca tagtccgtat tgtaatttag caaaagatga ttttctaaag catggactga
    25921 aactaagaca ccatttccta ttcccgcaac caatactaaa tgtaataccg ttttattctt
    25981 aacctttttc ttggaaacag caaaaattaa aattcccaga gcagctaagc tagcaccagc
    26041 aactagggct tgcctctcat tcttgcttcc agtatttggt aattccgcca gttgattttg
    26101 agaatttaac ttataaacaa gataataagt ttcatcatca ttctccacgt atgtcggaat
    26161 atcatagaca agctgcttct tttcttctga tgatagctct gaatctgcca catatttata
    26221 gtgaactccc gcagtttctt gagcatccac agatgaacta gctaatacag acataaaaaa
    26281 taaacttgaa atcgttgcag atacaagtcc tactgataat tttctaaatg aaaaacgctc
    26341 ttgtttttca ccaaaatact tttccattat tcctccttga aataaaattt atatatgtta
    26401 caaagacctt tattatatta gtgtattatc tattatctat agaaaaggca gtatacctta
    26461 attatactct taatttacaa aaaagtctta aaattgagat gcgctttcat actttgtttt
    26521 atattatttg ggggtacaat aacacctacc atgaaattta cacggtaggt gttactcata
    26581 tcactaatcg ttctaaaaat ggtttgaggc agttgaggag aattccttct atccagcttc
    26641 cttgtgctga tgagcgatag tcttcctgca ggcttttttt tagaaaatct cggacttgtt
    26701 ctggtgcgat ttcaaattca aaggctttca ttttatagaa aaagtcgatg agatgatctg
    26761 acaggtattc agttgaaaag ggtacttcac cattttttcg atattctaat aagagcctag
    26821 aaaatcgagc tttttcttca ggaagctcac gaaaatagga attgaggagc caagtctgtt
    26881 tctgttttct ttcaattgga tcctgactgg caattcgttg gtctttttcc agctcttttt
    26941 ggtattgttt ggccttaata gcccgttctg ctctattttt accaaaaaga attttttccc
    27001 acttgcgttc ttcttgagtc agggtctctg taaagccaaa gtaatcttga taagcacgct
    27061 ctgcgggtcc catggctaga accagattgt ctgcatattg cttggcgatt ttatccctct
    27121 tcttgcgttc tttctctgcc tggatacgga gttcttgttc gtagtcaatt ttctccttgc
    27181 ctagcttgac aaggtagagt tggtcatccg atttcccaag taaaaagggt ttgatacact
    27241 tttcaaggac ttcttccatc cgagcctttt tctttggttc cgccttggtc caacttcctc
    27301 cctgaaagac ttctaggaaa agctggtagt ctctctcagg cgcaaattga ttgccacgat
    27361 tgggtttgaa aacacctttt tcccagagcc attttagaag tcgctcgtca aagtcacttt
    27421 tattgacctt gattttttcc tttttctgag cttttctggt tagattttca acctttctga
    27481 gcagtttttc ttcctcttcc aattgctggt caagggacaa tcgatgaaaa tgacgaacac
    27541 agtcgctacc aattggaaag aggcgttggc ctgtgacacc gttaaagagt tcataagcgt
    27601 atttgatgac atttccacag acacaaatgc tacggccgat accgttaaaa atcaaggaaa
    27661 cttcattcca ttccttggta gcttgttccc aagtatccgc tttcgaagcc tgtaaaactg
    27721 catcgtgcag ggattttcta actggaagtg tcatgaggtc tcctttctaa tactcaataa
    27781 aaatcaaaga gcaaactaga aagctagccg cagtcagctc aaaacactgt tttgaggttg
    27841 tagatagaac tgacgaagtc agctcaaaac actgttttga ggttgtggat agaactgacg
    27901 aagtcagtaa ccatatatac agcaaggcga agctgacgtg gtttgaagag attttcaaag
    27961 agtataagtt atacttttac aacttgaacc tcgtctttac cgagtaaaat caagtatttt
    28021 tcaatatttt caatcgaata ggctcgtgat aaagcctctt cgtatagagc taactgacca
    28081 cgatagcggt ctacgagttg acttggttca tcatagcggt ctgtcttgta gtcgaacaga
    28141 acaattttgt tttcgtaaag cagatagcca tcaaggatac cacggacaac aaagtcttcc
    28201 tgactctttt ggtctcgttt gagcatggag aaaggttgct cgcgatagag atggtcggta
    28261 ttagcaagaa tttcctgacc gagtactgtg tcaaagaaag caagaatttt atcaagattg
    28321 atcttgtctc tgacagcttg gctagtttga acgtgtttga gtgtttctgt taggctagca
    28381 agggttagtt gctggctgag gtcaattctc tgcatgagtt cgtgagtagc actaccaatc
    28441 tcagctccag ttaccttttc tttggttgaa aaatctggca aatcgaagct gattttcttg
    28501 cctactgact gaccttgacc agcaatctcg acaccttcca tatccataac tggttcgtag
    28561 aatttcttga tttgacttgg ggtttgaaca ctaggaagtt caatagctgc gcggtgaaga
    28621 gtattataaa cttccacctc cttcagcatt tccagagctt ctttgatggt atctgactga
    28681 cgattgtctg cttgggagct atcttggaga ggactcttgg tttccaactc tccgatagct
    28741 tctctggtca actgatcttc gccaataaaa cgataactaa agttgagctt gtccttagta
    28801 aacactttac tgatagccca aagccaatct tggaaattcc gtgcttgcag tctagtattg
    28861 ctatttagtt tcccattttt ggctgctggg tattccttgg attccagctt ttcacgagaa
    28921 cccttgccga caagatagag ctttttctca gcccgcgtca tagcaacata cagcaaacgc
    28981 atctgctcag aatagcttgc tagctgtaat tcctcttcgt tctgcctata ggtcagacta
    29041 ggaatggaga gtttgatggt tttaggatag tggtcttcta ctgcccctgt ctccatcttg
    29101 gcaatatatt tgacaccaag accattctga cgactgagaa tgacttctga catagagtct
    29161 tgcttgttga aatcttgatc catattgagg ataaagacgt aaggaaactc cagcccttta
    29221 ctcttgtgga tggtcatgag ctctactgca tcttttggcg gtgcgacggc cacgcttgcc
    29281 aaatcgtgct gggcttctaa gacttggtca atcatacgaa taaaacgcga caaacctttg
    29341 aaattgctct tttcaaattg atcagcacgc agtgctaggg catagagatt ggcctgccta
    29401 gcaggaccat tcggcaaagc cccaacatag tcataataaa aacggtcgtt gtaaatcttc
    29461 caaatcaagt catagagaga gtggggtttg gcatacaagc gccaagaagc taggatatcc
    29521 atgaattgct ttagtttttc agctagagct gtgtgaatca agcctttttg actacttgcc
    29581 attttttgtg cattgaccag tttctcatag agattttcgt ggactttatc ctctgctttc
    29641 tgaagggaca aacgtgctag ctcatcctca tcaaaacaaa acattggaga cttcataagg
    29701 gcaaccaagg cgtagtcttg caggggattg tgaatgacac gaagagtgtc tagcatgact
    29761 tgcacttcta gggattggag ataattgttt tgctctccgt cagttttgac aggaatcccg
    29821 tactcagaca gggcgaggag aatctggtca ttacgactgc ggctggaggt cagaagggca
    29881 atttccttaa aggcaacacc tttttcttga tgaagtttca gaatctcctt gataactaag
    29941 cgcatttcgc ctgttagttt cgtttctgtt tgactctctt cttcctcacc tgtatcgtcc
    30001 ttgtcgtaga ggagaaattc agccttgttg tctggattgg gagtcagttt ggtattggca
    30061 aaaacaagct ggtgcatgtt atcatagttg atttcgccga cctcttggtc catgagacgt
    30121 tcaaagacat cattggttgc tgacagcact tctgaactac tacggaaatt ttccttgagg
    30181 agaatgagct tgccttcttg aggattttgc gcatagcgtt ggaatttctc attgaaaatc
    30241 tgcgggtctg cctgacggaa acgatagatg gattgcttga tatctcccac cataaagcga
    30301 ttgtggccat tagacaacaa ttccagcatc cgttcttgaa tatggttggt atcctgatac
    30361 tcatcgacca tgacttcatg gaagcgctcc tgataagact cacgaacttg tgggaaattt
    30421 tctaaaatct caatggtgta atggctgata tcagcgaatt caaaggcatt ttcctgtcgt
    30481 tttctctgac gataagcctc tacaaaatcg ctcatgaaag attggaaggt tttagctagt
    30541 ttccaagtgt ctccatgata acgttcttga tagtcgagaa tcgctatctg gtctgataat
    30601 tgtcctagtt tagtaaactg ggtctttctc tcttcgttgt aggcatcagc caggggcttc
    30661 aaatcagcct tacggctggc attagtcaga gcacgaccgt ttttctcctt agagatggcg
    30721 acaacacgcg caagtactgc ctgataagcc tgactatcga actcctgatt tagggagcca
    30781 atttcatcca gaattaactg aacattttct aaataggcag cctttgcaaa ctccttggca
    30841 tcgttatcca gatggtaacg gaaaaagctt tccaaatccc agagggcttg tttgatttgc
    30901 tcagtcagtt tttctttttc actggtaaaa tcagctttct caaagccttt gaggaaagat
    30961 tcactcagcc acttttgagg attactggtg gattggagga agtcatagat tttatagact
    31021 tgctggcgca gaccccgttc gtccttgcca cgcccagcaa agtttttcag caaatgacta
    31081 aagctctctt tctgtttacc ttggtaatgc gcttcaaaga cctcatgaaa gacttcgttt
    31141 tcgagaagaa gttgctcgct ttggttttgt aaaatacgga aattaggtgc aatatcaagc
    31201 agataaccat gtttgccaag gaatttttgt gtgaaagagt ccatggttcc gatggcagcg
    31261 ttgggtaggt ctgccaactg gcaacccaag tgttgtttga gatcgacatc atctgtttct
    31321 tggattttct tgctgatttt tttctctaaa cgttctttaa gttcagttgc agccttgacg
    31381 gtaaaggttg agataaagag ttgagaaatt tcgacaccac gcgccaattg gtccagaatg
    31441 cgctctacca tgacaaaggt ctttccagaa ccagccgatg ctgagaccag gatattctga
    31501 ccagaagtgt agatagcttc gatttgttcg gcagttttct tctgttcctt gctcgaattt
    31561 gcttctgctt cttgcagttt ttgaatctcc tcctcactta aaaagggaat aagcttcatc
    31621 gatttaactc ctctcttatt ttttcaaacc aagcttgctt gagtttttct ccgaccagac
    31681 gcttgccatc agctaggtcc aacttttcta ggaaacgggc ttggcccaga tggtaattgg
    31741 cttcaaagcc tgtaatagcc tgatgttgct ggacgtatgg ggcaatgctt ctgccatttt
    31801 cagtataagg attgatggcg aaccggcctg ctaaaatctt ctcagcagct ttcttgtaaa
    31861 gataggcatt gtagtccagt aggagctgaa attcctcatc tgtcagttga ttagccttgt
    31921 ttttgttata aaattcgcct aaataactgc tttctttttc caagaagagc ccttggtatt
    31981 tcatagattt gctggcttct accactgctc ctgccagact ttttaccgcc atcagagatt
    32041 ggacaggttc agccatttcc aagtacatgg cgccgaaaaa gttctgctcc ccttctcttt
    32101 ttagggcagc aagataggtt ggtaactgag aattgagccc attaaagaaa tgaggaaact
    32161 ggaactgagt cagactggat ttgtagtcta ctactcctat cgctccatta gctttcaaac
    32221 ggtcaatccg gtccaccttg cctcgtacaa agacactgcg tccattgtct aattgaataa
    32281 aggcttggtc ttttccacca aaatttgctt cttctttgat ggtttcgatg gctggattgt
    32341 gtcggagaat atgtccagtc gtccgtgcaa catcaagcaa aacttccttg gtaaactggg
    32401 cttccaaact ttcttgataa atagcttcaa attcgcgttc ttgactggtt tcttgaatag
    32461 cttgttctag acgttggtca aaggaatctt cattaggcaa ctgtaaggcg cgttcaaaga
    32521 tacgatgcaa gaaattcccg tgactacggg catcaggatg caaacgtaat tcctcctgca
    32581 agcctaaaac gtagcgtagg aaataactgt attcattgcg ataaaactct gtcaaacccg
    32641 acgtagacag gtaaaactcc tgtttggcag gatagagagc ttgcaaggtg tccttggcta
    32701 aggtcttgct gcttggactg gttgggatag ctggattttc cagaccttgc tgatctagtt
    32761 ttttacctat gacacgcgac agaaccttga caaaagtcaa atcttgctca gtatcgctca
    32821 tctcaccctg ctggtgatag gcaaccagac tagacaaaag actgtgatag gaccccatat
    32881 cctccttaga cagtcctttg tgattcatcc tcttctctct ccgcctaaat ccaaaatgga
    32941 tcaactcttg aagataggca gattccttac tttcactttc gttaaaaagg cttggagccg
    33001 acaagaacaa ctgcttacga gcagaattga ccaaggaaag catagtgtag cgatttttct
    33061 tgagattttc actgctggca atcagtaatt gaacgccttc ttcggtcgtt tggtttaggt
    33121 ttttcctttc ttcatctgtc agaagactgg tgttttgaga aatttttggt aaattgtcct
    33181 gagttagtcc aatagcatag acaaagtcag cagtcaatgg tgcaatcaaa tcgtaactct
    33241 gcaccagaac agtgtccact gttgctggaa tggtacggta ttgggacaaa ctcattccag
    33301 aatggagcaa ggctaggaag tcttccagac taacctgtga accagcaaaa acagtcgcaa
    33361 attgttctaa aacatggcaa aaagccttcc aaacttcggc ttgtctttcc tgttctacag
    33421 cttccaaagt ggttgtcaaa tcttgtaact gcttggtcac agctccttct tttagaaaga
    33481 cactccattt ttgtaggagg ttttcagcct tttgttttcg gctggcaaag agggtttcaa
    33541 gaggtgctaa aattctcagg cggaggacat tcaaacgctc aagattaaat tttccatggt
    33601 gggatttggt gaaggtttgc tgaaaggctg gcaagccatt aataccaaga tagcggatat
    33661 attgttcaaa agcatcaata tcagactgac tgaggtcaat atacaagtca gttctaagaa
    33721 gattaatcaa atcctcctga cgaaaacggt aacgttttaa agctaaaata gactcgacaa
    33781 actgagtcaa gggatgatga gccatggctt cgcttctacc aagataaaaa ggaatctgat
    33841 actggtcaaa aatggttttg agagataact ggtaagaagc tacatccccc aagagaatac
    33901 gaaaatgctt gtagctcagg tctgagttct catgtaattt ctgacgaatg ctacgggcta
    33961 ctagctccaa ctcctccttt tgcgtcaaac aagaccagat ttgtaaattt tcacggtctt
    34021 tctcatcgac atccaaagcg agttctgaaa agtcataaga agactccaac aaacgagagg
    34081 ccttgtcaaa actatccatc ttctcatgag tttgagaaca gtcctgagcg ggcgtttggt
    34141 atttagaagc cagatgatgg agaaatttta cgctggcttg gtagagattg ccctcgctaa
    34201 aaggactggt ataggctttc ttactagcat aagccccgat aacaatctca gcacctttgc
    34261 cgtgaagtaa gtccacaacc cgctcttcct cagcagaaaa acgagtaaag ccgtcaatga
    34321 ccaaggcgat ttgattaaaa tcactactta ccttgtcatt ctcaatagcc tcaatcaaat
    34381 gggacaactg acttccctgg gctaactgcc cttgattaag ataggctgtt actttctcaa
    34441 aaatcaagag taaatccgcc ctcttatcct catctgttaa attctccaag tccaaaaaat
    34501 tcatctgaga tttggtcatc tcatggtaaa gctcaattaa ctgctggatc aattgaggat
    34561 cctgcttaat agcgccataa acacgcaagt ccttgggatc gagttcggca aggcatttgt
    34621 aaaaggccaa cccaagaccg atatcatcaa gagtagtttt agctggtaaa tcattcaaga
    34681 ccagataacg agccatttga gcaaagcgcg tgacggtaat cgaaaaagaa gcctgctggg
    34741 acaagcattc cagcacggcg cgttcctttt caaaagaaag agagttgggg gcaatgtaga
    34801 agacccgctt gccagctgca actagctctt ctgcctctct tgttagaatt tctgtcaaag
    34861 aagttcgaat atcagtataa agtaatttca tctcagcctc gttggaattt ttcatcaccc
    34921 tatattatac catgattagc ctcgtaaatc tgttaaaata tttaggccat cctttctttt
    34981 cttcatcatc tgctaaatct taaatactta gctttacttg tattagatag aataagtctg
    35041 gctactgaaa atcacataat aaaaaagcct cggtaacaag gctttgagtt ttatgattgt
    35101 ttcttaggta cggaatacac ttcaatgtgt tgtcccagta tcttaatgtc gacgggtaga
    35161 ttgtctgatt tatcgccatc aacatcggac tctaattcga tatcagaaga agttttaata
    35221 ttacgtgcct ttatatattc aatattcttg atagaatgat tgaactatag taaattgaaa
    35281 ctataatagt acaccgtgga tgctaaaata tttctagaaa ttaatttgat ttccctaatc
    35341 aagctgttcg tatcttattt caatcta
//
LOCUS       DAVKMJ010000024        35303 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000024 DAVKMJ010000000
VERSION     DAVKMJ010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35303)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35303)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35303
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.024"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(34..684)
                     /locus_tag="VW348_001186"
     CDS             complement(34..684)
                     /locus_tag="VW348_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEU9746084.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRMHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            796..1638
                     /locus_tag="VW348_001187"
     CDS             796..1638
                     /locus_tag="VW348_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU9746085.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            1714..2151
                     /locus_tag="VW348_001188"
     CDS             1714..2151
                     /locus_tag="VW348_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEU9746086.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            2220..2522
                     /locus_tag="VW348_001189"
     CDS             2220..2522
                     /locus_tag="VW348_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746087.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(2613..3686)
                     /locus_tag="VW348_001190"
     CDS             complement(2613..3686)
                     /locus_tag="VW348_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEU9746088.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            3842..4519
                     /locus_tag="VW348_001191"
     CDS             3842..4519
                     /locus_tag="VW348_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9746089.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            4512..5486
                     /locus_tag="VW348_001192"
     CDS             4512..5486
                     /locus_tag="VW348_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU9746090.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(5535..7478)
                     /gene="thrS"
                     /locus_tag="VW348_001193"
     CDS             complement(5535..7478)
                     /gene="thrS"
                     /locus_tag="VW348_001193"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEU9746091.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(7536..7859)
                     /locus_tag="VW348_001194"
     CDS             complement(7536..7859)
                     /locus_tag="VW348_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEU9746092.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            8718..9347
                     /locus_tag="VW348_001195"
     CDS             8718..9347
                     /locus_tag="VW348_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEU9746093.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGAGS
                     LYIDETKTTRLLDTSDFPEEFKSLAKAQADEFDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNGKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            9488..9757
                     /gene="rpsO"
                     /locus_tag="VW348_001196"
     CDS             9488..9757
                     /gene="rpsO"
                     /locus_tag="VW348_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEU9746094.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            10572..11186
                     /locus_tag="VW348_001197"
     CDS             10572..11186
                     /locus_tag="VW348_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEU9746095.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIQRL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(11479..12228)
                     /locus_tag="VW348_001198"
     CDS             complement(11479..12228)
                     /locus_tag="VW348_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEU9746096.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            12361..14697
                     /locus_tag="VW348_001199"
     CDS             12361..14697
                     /locus_tag="VW348_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEU9746097.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLDY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELMAMAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRRSMLRALPSALMVVFGVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEIATLTGQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            complement(15134..18280)
                     /locus_tag="VW348_001200"
     CDS             complement(15134..18280)
                     /locus_tag="VW348_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000621470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HEU9746098.1"
                     /translation="MIRTEVTSMTVPDRLPARMRMDGRSIFQQIKNYFDTENKEYFKH
                     PNTYDGISMHLEPNILTSMEHFDLTGFHCECKDFQNQGVCKHWVAMDLYFRSLPQAIQ
                     ERIGKASHKPSFASQLIPTLPSEELQDELVEEKATAPSLALHGQVEIRNHSLAWTLKL
                     QVEQAPRAYVIKDIAHFIFLIFQKEDYFVSQKIGTIRLSLNQFNQASQNLLLYIKKYF
                     IDRNEHSYFNFSYGINPRDYGRYLETPVSYLNDLVPLFQALDVFQYVTSKAEYPLIFL
                     DDSPFIPEEEIFKVVKSNNHYEIINTAYFGFIIQEKLWIRHNHFHIIKEEHRYFLDKL
                     ATWIYHYQENSPLIFSKENKAELMQVCNIISNYVPISIPDELQIHDFIPTFAFSKTRN
                     EIALNMVWSFGEKQVHSKQDLLTLPYTYQASKARKIYHQLLSAGFKEEFHSLSKIKIV
                     DFFLKELPRFRTLGQVQLDESLEKLLVEDPAVIDIFDDESFLSVQFDFSMISEDEVEK
                     AIQALWNQESHYQTKQGKVLVFDDESLKVAQSLQDLRAKFSDGKIKMHKSRAFSLSET
                     FKDNEHVNFSRDFKKMAYDLTHPEEFDIKPYEVKAKLRSYQKEGVKWLSMLDHYHFGG
                     ILADDMGLGKTLQTITLLEANLKPDQKALILAPASLLYNWKEEFRKFVPHKQVEVAYG
                     SKTERIKQIEKSATITITSYPSFRSDLEHYQKQSYDYLILDEAQMIKNSQTKTAQALR
                     EFDVKTCYALSGTPIENRLEEIWSIFQIVLPGLLPSKKEFSKLSPQLVAKLIQPFVLR
                     RKKDEVLTELPELSEHLYSNELSSSQKTLYLAQLRRMQEMVSGASAYEIKRHKIEILA
                     GLTRLRQICNTPALFLEDYKGDSGKMDSLFELLDTIREKGSRPLIFSQFTSMLDLIEQ
                     ELEKKEMSHFKITGQTPSDKRQEMVNLFNQGEKDCFLISLKAGGTGLNLTGADTVILC
                     DLWWNPAVEMQAIGRSHRLGQTKQVDVYRLITLGTIEEKIQELQESKKELFNTVLEGQ
                     ESRSNLSVDDIKEILGVE"
     gene            complement(18469..19707)
                     /locus_tag="VW348_001201"
     CDS             complement(18469..19707)
                     /locus_tag="VW348_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746099.1"
                     /translation="MHIFLKNRAFRQLTVNEWISSFGDTIFYLAFINYVSSYAFAPLA
                     IFLISLSETIPQVLQLFTGVIADFQKNRISKYISILFIKVLLYSGVTLLLTSTDFSLF
                     SVFFICSMNLISDTIGFLAGYMLTPIYIRLINDDMTEAMGFRQSTSSIVRLIGNLSGG
                     VFLGLFSISTLAFVNVLTFLFAFLGSLLIRNRLKKEEEKIEVPPYVGMSSFFQHLKES
                     MKLLMTMEDVMVLLWILSISQAVLMMVEPVSAILLIHHPFMGLSTGQSLAILIMISLL
                     HVILGGLLSGFLSKKISIRLNIYWSLLMESLIVIDFLRGSFLLILLGSAGDAFSAGVL
                     SPRLQAMIFGIIPEELMGSVQSSINVINLLIPAVLSLALVFLATSAGLEVVAFALIIL
                     LLIAAYLVHQMKNLPNQEEV"
     gene            complement(19709..21145)
                     /locus_tag="VW348_001202"
     CDS             complement(19709..21145)
                     /locus_tag="VW348_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HEU9746100.1"
                     /translation="MTPIKDKVRRVKTPMMVNPDTDLTISSVQQDYFSLALIGFSLLT
                     GDFLSFSKGDQKTGLSAFIKICHLIKIARLDNKITKQQEYWLYDLLMMSQGEKIQKIK
                     QLKQVTSDILLNTPDFSSYFEKYNFKEEAENIKSYLLAKSMDKSGRLFPSNEFGEFVS
                     PVSFQHGFGGVLFFMNKYYVEEDENTVKEWLTKLENYEAANFLHGYSLLFGKAGFLFG
                     ILDRYEKTKERYLIDISKRLVDHLMRVYDNISNLDFALGKSGILLSLMKYCTIFDDKK
                     LANFIKNNINDAYSLLESEDNGDIYSNNFAHGRSGAAYVLKAYTDIFGDSRYQNHLQK
                     FSDGISELLEEKLSSFSKLDNLGLSWCDGVSGLILYLCLIDKERYSEIIYKSQLEMVQ
                     QYEAMGTSFCHGLSSLLQTTIYNKNQKVEQFIKKILLTRSYRNNDRLLQFQGEDGINS
                     YFDFGVGNLGIYWTLLGYTFPFELSKGD"
     gene            complement(21219..21749)
                     /locus_tag="VW348_001203"
     CDS             complement(21219..21749)
                     /locus_tag="VW348_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HEU9746101.1"
                     /translation="MLDEKRKNYVEDKRQNFPSLPSWKMDLFSEEEKRIYFQTTCEVS
                     SKDSAINKYKMEKIIKRSNKGNVYRAIRKSDGQKVIIKQSRPFVNYDAEGEWTALDDI
                     KNEAHMLKKLADKSYTTNLTDEFYIVDDYFLVQEQVDGLNFEEFIRETEHSLNIREKT
                     LDNIVNIVSYIHKLGI"
     gene            complement(21743..22211)
                     /locus_tag="VW348_001204"
                     /pseudo
     CDS             complement(21743..22211)
                     /locus_tag="VW348_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22760..23437
                     /locus_tag="VW348_001205"
     CDS             22760..23437
                     /locus_tag="VW348_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEU9746102.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLCKEVSPVFVQKWQKEAVKLEFALGQIPDKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            23424..24221
                     /locus_tag="VW348_001206"
     CDS             23424..24221
                     /locus_tag="VW348_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEU9746103.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLEIEETTYLQETGPERGIGRIGNIQPQTFGELAQHVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            24238..25341
                     /locus_tag="VW348_001207"
     CDS             24238..25341
                     /locus_tag="VW348_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEU9746104.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQEIDFYQRSGVFLLKKDESNLE
                     ELYQLALQRREESPLIGQLAILNQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            25642..26661
                     /gene="galE"
                     /locus_tag="VW348_001208"
     CDS             25642..26661
                     /gene="galE"
                     /locus_tag="VW348_001208"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU9746105.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            26663..27598
                     /locus_tag="VW348_001209"
     CDS             26663..27598
                     /locus_tag="VW348_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9746106.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTNWSFRQLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSYHRS"
     gene            27773..28417
                     /locus_tag="VW348_001210"
     CDS             27773..28417
                     /locus_tag="VW348_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746107.1"
                     /translation="MLSKEEYIEEIGLIEKQNYVEVELYPLVADIINPTLKNSLSKRY
                     VFGRRKSNMGQIYYGLSNFPDIVILDKNYQNKARKSIEIEEWKKLRGCVEIKSLKHDL
                     ITEEKIKSTISNSFEHITGEMGQLIGDLLWYKKVIYTNGIEWRFLSLDDKEEIDNTIV
                     QVVNKRIETEEAGNSFDWWKNIKDLSFNYTDIYLSKDCIQEWDEFVKKVKEIEW"
     gene            28456..28557
                     /locus_tag="VW348_001211"
                     /pseudo
     CDS             28456..28557
                     /locus_tag="VW348_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group 2 glycosyl transferase"
     gene            complement(28608..28814)
                     /locus_tag="VW348_001212"
     CDS             complement(28608..28814)
                     /locus_tag="VW348_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEU9746108.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDILEAVKNCPTRALIGNQEA"
     gene            28866..29342
                     /locus_tag="VW348_001213"
     CDS             28866..29342
                     /locus_tag="VW348_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEU9746109.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKGFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMVTGSWFANPGDVIKIK"
     gene            29351..30022
                     /locus_tag="VW348_001214"
     CDS             29351..30022
                     /locus_tag="VW348_001214"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEU9746110.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            30153..30491
                     /locus_tag="VW348_001215"
     CDS             30153..30491
                     /locus_tag="VW348_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEU9746111.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            30494..31123
                     /locus_tag="VW348_001216"
     CDS             30494..31123
                     /locus_tag="VW348_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEU9746112.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            31363..32514
                     /locus_tag="VW348_001217"
     CDS             31363..32514
                     /locus_tag="VW348_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9746113.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            32827..33576
                     /gene="truA"
                     /locus_tag="VW348_001218"
     CDS             32827..33576
                     /gene="truA"
                     /locus_tag="VW348_001218"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEU9746114.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            33566..34339
                     /locus_tag="VW348_001219"
     CDS             33566..34339
                     /locus_tag="VW348_001219"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU9746115.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            34317..34778
                     /locus_tag="VW348_001220"
     CDS             34317..34778
                     /locus_tag="VW348_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9746116.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     AIIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            35005..>35303
                     /locus_tag="VW348_001221"
     CDS             35005..>35303
                     /locus_tag="VW348_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9746117.1"
                     /translation="MKLTYDDKVQIYELRKQGYSLEKLSNKFGINNSNLRYMIKLIDR
                     YGIEFVKKGKNRYYSPDLKQEMINKVLHEGWTKDRVSLEYGLPSRTILLNWLAQY"
BASE COUNT        10349 a         6402 c         7628 g        10924 t
ORIGIN      
        1 aaaactttca gggttggtag gggacttgag aaattagttg attttctcga catagagttg
       61 ttttgcaatg tccatattca cttgtaaatc ctcgtcgtta ctgaggatag tgaaggtatt
      121 gctgaagcca tcaaactgct taacttggag ctggtcaccg atgtgaagtg agtgcttgtc
      181 cagataatgg agaatgtcaa aactatcgtg catccgagtc aggcggtagg cgccagcttc
      241 cttgatatca gctagtggga ggttattgat ttcaacgagg agttctccct tggcaggaat
      301 agttcctccg tgggggcagg ttttagggaa acctagcagt ttatctagtc tttccacgaa
      361 caggtcagag acagtgtgtt ccaagacctc agcttcctcg tgaatctggt cacttgtata
      421 gtctaaatga tgaactagaa aaacttcaat caagcggtgc ttacgataga gctcagagac
      481 cagtttgaga ccgaggtcag tcagtagata gccacattcc ttgtccttta ggatgagatt
      541 ttcacttttc attcgtttga tcatttcagt tacggcaggg ggagagactt gcatgcgagc
      601 cgcaatttcc ttgttggtaa tcttatgcag gtctatgcca atttcataaa tacattttag
      661 atagtcttct ttgtttgggg tcattcgttt cctcttgtct aatatcttta tctagtatat
      721 caaaaaaagc tagatttctc tagctgtgac tttttatgtt atacttattg caagagaaaa
      781 aacgaggaga tggatatgac gaaaatagct cttctttcag atattcatgg aaataccacc
      841 gccttggagg ctgttttggc agatgctcgg cagctaggag tggatgaata ctggcttttg
      901 ggagatattc tcatgccagg gacagggcgt agaaggattt tggacttgtt ggatcaacta
      961 ccgattacgg ctagagtttt gggaaactgg gaagacagtc tttggcatgg tgtccgtaag
     1021 gaattggata gtactcgccc tagtcaacgc tatctcttgc gccagtgcca gtatgtttta
     1081 gaggaaattt ccctagaaga aattgaagtg ctccacaatc aacctcttca aattcatcgt
     1141 cagtttgggg atttgacagt gggaattagc catcatctgc ctgataagaa ctgggggcga
     1201 gagttgattc atactggcaa acaagaggag tttgaccgct tggtgactca tcctccctgt
     1261 gatattgctg tttatggaca cattcaccag cagttgcttc gttacgggac tggtgggcaa
     1321 ttgattgtca atccgggttc gattggccaa cctttctttt tggacgctca gctacggaag
     1381 gacttgcggg cccagtatat gattttggag tttgatgaca agggcctggt agatatggac
     1441 ttccgacggg tagattacga tgtggcagct gaattgcagc tggctaaaga cctgagactt
     1501 ccctattttg aggtttacta tgaaagtctg gtcaatggga tccaccatac tcatcatcag
     1561 gaatttttga gagaattggc tcagaaagag ggttgcgatc gggagttaga cgactggttg
     1621 aaaagtggta acgattgaca ttacaactaa aaagggtata ataatagaaa aagaagagta
     1681 gaggcagggt agcctcgtaa aaaggagaag aggatgcaaa ttccaagtag atttaccatt
     1741 gcaactcata tgctgataat cattgccctc gaggggaagg aaagcaaggt gaccagtgat
     1801 tttctggctg ctagtgttgg ggtcaatcct gtcattatca gaaagatctt gtcccagttg
     1861 aagaaggcag agctgatttc agtagcgcgt ggaacgggcg gaacagagat tgtcaaggac
     1921 cttaaggata ttagtctttt agatgtttat caggcggtcg aatgtcttgg taagacaggt
     1981 caactcttca gtttccatga caatccgaat ccaaattgcc ctgtaggagc tcatattcat
     2041 gatgttttgg atcaaaaatt ggagagaatt cagttgacta tggaggcaga acttggtcag
     2101 accagtctag aaaaagtcgt ggccgatgca gagagtcaga tgaaggatta agagggataa
     2161 atgccctctt tttttctttg gataattatg ataaaatgta gctattaaag gagtaagaaa
     2221 tgtatctcgt tatagaaatt gtattagcct ttatagtgtc attttggaag gataatagaa
     2281 gtttgtggaa tccagtatta tttttattat ccctcatttc aagttatttt tatctatcct
     2341 acctttttta taaaaatgga tacgagaatg ttcagttagc tttttatgta tttgcctttg
     2401 tcttacttcc ttttttgctt tttctaagtg gcatcttttt aatctataat ggggtcattt
     2461 tgttgaaacg agagggacgt tccaagcccc attatctctc aatgctcttt gatttttatt
     2521 gactattaga ttctatttaa aaagacttag aatgaacatg aaagtatgta ttctaggtct
     2581 tttgttttgt atacatttaa ttttcaagag tattatctat ttttccatgc atggtaacga
     2641 gtatcaatca ataactgggt aaggcgaccc aaggtttctc tttcttctgg agtgagggat
     2701 tgagcttgga caaagagatg atgaatgtat tcaagcgcct ttaaggaagc caagtcattg
     2761 atagagctaa taccagcatc aagaatagtg ccaaagaaga ggtcgaagta gagctgaagt
     2821 tcttcgtcag ggactgtggc cacccattct ttaaaggttg tgtctacttg ccggctatca
     2881 ctgttggtct tatccagttg aacgaagtgc ttgtcctcaa tctgccaact aaaggtatcg
     2941 tgctgggcga tgccacccag ggcagtactc tgaacgatga tttggtgagc aggaatttcc
     3001 agcatcatac cgataatgga accttgtgga atgaatatct tgcttctatc cattatcctt
     3061 tgataacccg cagtctgtgt caattcttga tggagaccag gtgcatcaaa tgtataaact
     3121 gctgtgatct gattttgcaa actttgctca atttggctag cagcatagat agcgagattt
     3181 cctcccttgg aatgcccagc cagaataacc ttttgcttag gatgatgggc aaaaaagttc
     3241 tttaaatagc gaagggcgtg cttttgagca ggaatttcct tcatataggt caggtggaaa
     3301 tcttccttcc agccaatgat actgtcatct gtcccacgaa agacaatcag ataggtatcg
     3361 aggctgacac gataagtcat agccgcaaat tgcttttgca gttcagggtc gatgtcgttg
     3421 ataaaatggg agagtttgca atttttgaag cgcttgtgtt gagccaattc atctaataat
     3481 tgaaggcgat ttttgctagt aagcatggtg ggctctcttg gaacctgagg tgctagatct
     3541 aaaagacgtt gaggaagtgt ggagaccaga ttatcaaagg agaggtaggt gatttctatt
     3601 aaggttagaa tgtctaactc attcaaggga aggtcgtaat aagaatcata tgcgacatct
     3661 ttcagatagt caaaaatatt ggccataaga gctcctttct ttttatttat cttagcaaat
     3721 ttccctcaaa ttagctagta gcatagcctg tttgtactgg ctaaaaacag gctatttcaa
     3781 attcagtttc agaccatcta gcatggaaaa atctgttata ataatggaaa aggagaagcg
     3841 catgcacaag attttattaa tagaagatga tcaggtcatt cgtcaacaga ttgggaaaat
     3901 gctctctgaa tggggatttg aagtggtcct ggtagaagac tttatggaag ttttgagtct
     3961 atttgttcag tcggaacctc atctggtcct catggatatt ggtttgccct tgtttaatgg
     4021 ttatcactgg tgtcaggaaa tccgcaagat ttccaaggta cctatcatgt ttctttcttc
     4081 gagagaccag gctatggata ttgtcatggc aatcaatatg ggggcggatg actttgtgac
     4141 caagcctttt gaccagcagg ttcttttagc taaggttcag ggcttgttgc gtcgttccta
     4201 tgagtttggg cgtgatgaga gtttgctgga atatgctggt gttatcctca ataccaaatc
     4261 catggattta cattatcaag ggcaagtctt gaatttgacc aagaatgaat tccagatttt
     4321 acgcgtgtta tttgagcatg caggcaacat cgtagcacgt gacgacctga tgcgggaact
     4381 ttggaacagt gactttttca ttgatgataa taccctctct gtcaatgtgg ctcgtttgcg
     4441 taaaaagttg gaggagcagg gattggtagg atttatcgag accaagaaag gaatagggta
     4501 cggattgaag catgcttgat tggaaacaat tttttctagc ctatctgcgc tcccgtagtc
     4561 gtctttttat ctatctgctt tctttggcat ttcttgtctt actctttcag tttttatttg
     4621 ccagtctagg aatttacttc ctctactttt tcttcttgtg ttgctttgta accatattat
     4681 ttttcacttg ggacatattg gtggaaacgc aggtctatcg ccaggaactt ctctatggag
     4741 agagggaagc caagtctcct ttggaaatag ctttagcaga aaaattagaa gcgcgtgaga
     4801 tggaactcta tcagcagagg tcaaaagcag aaagaaaact gacggatttg ctggattact
     4861 ataccttgtg ggtccatcag ataaagaccc ccattgcagc cagtcaactc ttagttgcag
     4921 aagtggtcga ccgccaactg aagcagcaac tagaacagga aattttcaaa atcgactcct
     4981 ataccaacct agttttacag tacctgcgtt tagaaagttt ccatgatgat ttggtcttaa
     5041 agcaggttca aattgaggac ttggtcaagg aaataattcg taaatatgct cttttcttta
     5101 ttcaaaaagg cttaaatgtc aatctacatg accttgataa agaaatcgtg acggataaaa
     5161 agtggctgct agtggttatt gagcaaatca tctcaaacag tctcaagtac accaaggaag
     5221 gtggtctgga gatttatatg gatgaccaag agctttgtat caaagatacg ggaatcggga
     5281 taaaaaacag tgatgtcctc cgagtatttg aacgtggctt ttcaggatac aatggccgtt
     5341 tgacccagca gtcctctgga cttggccttt atctatctaa gaaaatttct gaagaactgg
     5401 ggcaccagat tcgtatcgag tctgaggtcg gaaaaggaac gacagtgcgg attcagtttg
     5461 ctcaagtgaa cttagtcctt gagtaaaaat agatgagaaa aagcctccag attggaggct
     5521 tttatgctag actcttattt ctcaacgcgt gatttgttgg cgatatcagc taggatagct
     5581 tgaacaaaat tatcaactga gacagtttgt gtttcttttt ggccgtagcg acgaacgttg
     5641 actgtttcgt cttccatttc tttgtctcca acaattaatt ggtaaggaat cttgctggtt
     5701 tgtgaagcac gaatcttgaa ctgcattttt tcattgcgct catctacgtc tgcacggaca
     5761 ccgcggtcac ggagtttctt ggccacttcc caagcgtagt ccacgtgttt ttcgttagat
     5821 actgggatga gggttacttg gtgtggtgcc agccatgttg ggaaggcccc cttgtagttc
     5881 tcaatcaaga tagctgtgaa gcgttccata gttgagataa ccccacggtg gatcatgact
     5941 ggacggtgat cttcgccatc agctccgatg tatttgaggt cgaagcgttc tggcaacaag
     6001 aaatcaagtt ggatagtaga aagggtttct tcttttccaa gggcagtttt aatctggata
     6061 tccaattttg gtccgtagaa ggctgcttca ccttcggctt caaagtagtc cacgcccatt
     6121 tcatcaagag ctgcacgaag catggtttgg gcattttccc acatctcatc gttatcaaag
     6181 tacttatgag tatcttgagg gtcacgaaga gagaggcgga agcggtagtc agtcaagttg
     6241 aagtcttcat aaacatcgat aatcaactga agggcacgtt ggaattcttc ttggatttgt
     6301 tctggagtaa cgaataggtg accgtcgttg agtgacattt cacgtacacg ttgaaggcca
     6361 gtgagggcac cagatttttc gtaacggtgc atcataccga tttcagcgat acggattggc
     6421 aattcacggt aagagtgaac atggtgtttg aaaacttgga tgtggtgcgg acagttcatt
     6481 ggacgaagga caaattcttc cccgtcaccc atgtccatgg ttgggaacat gtcttcttgg
     6541 taatgatccc agtgaccaga agtcttgtaa agctcaacag aagcaagtgg tggagtgtag
     6601 acgtgttggt agccagaagc caactctttg tttacgatgt agcgttccaa ttcacgacgg
     6661 atagtcgcac catttggcaa ccagaatggc aaaccttgtc ccacttcttg tgaaatcata
     6721 aagaggtcaa gctctttacc aagtttacgg tggtcacgtt ccttagcttc ttcacgcatt
     6781 tgaaggtagt ttttcaagtc tttcttgtca aaccaagctg taccgtagat acgttgcatc
     6841 atagcgttgt cgctgtttcc acgccagtac gcaccagcta catggagaag gtggaagatt
     6901 tggatacgac ctgttgatgg aacgtgaggt ccacggcaga ggtctacata ttcaccctga
     6961 cgatagatag tcaaaccgcc ttcgtcttct gagtgttctt caatcaattc caacttgtaa
     7021 gggtcatttt tgaagatttc acgtgcctcg tctttagtca cttcttcacg aatagatggg
     7081 aagttttctt tgacgatttt ttgcatttct tcttcgatac gaggaaggtc ttcgttagag
     7141 atttgaccag ctgtgttgtc agtatcgtag tagaaaccat cttcgatggc tggaccaact
     7201 cccaagtgaa tgtctgggaa aagacgacga gctgcttggg cgaacaagtg agctgctgag
     7261 tgacgcaaga ttggaagggc atcttcgtga tcaggtgtca caatttcgat gcttccatct
     7321 tcagtgatag cgcgagtagt gtcgatgagt ttgccgttga atttaccagc caaggctttt
     7381 ttagctaggg aattgctgat agattgggca atttcaaaag ttgttacgcc agattcgaat
     7441 tcacgaacag cgccatctgg gaaagtaatg ttaatcatga tgttctcctt ttttattatt
     7501 tcatagtttc taagcattga ttttttatca gcagactact tccaagtcct aacgttcaat
     7561 tgcttttctt tatcagagag gaagttttcc atttccgtca gaatgtctat atccaaacgt
     7621 tgagaaagtt ctaatagcca ccagatattt tctgaaagtt tttgttccag tgtgtagggt
     7681 gtttcatcat agtagcgtcc ttgctttgtc atcaccagtc gttggaaatt tccaatatca
     7741 ttagataaag ccaagaggtc ttcttctacc gtccacttga aatcatgatg cttaacttcc
     7801 agttcgtgat aagcttgtcg gattgcccaa ctgcgctcca ctaattcttg caactccata
     7861 attagtatcc taataaaaaa atgcgacatc ctcgaaagga cgtcgcaacg tggttccacc
     7921 ttcatttatg tacctcaaaa gagagggaca cctctgatcg gctctaacgt ggccaccgtt
     7981 ttatgttttc ataaaaaact caagagtagt atcagtttag acttcctatg cgtttccagc
     8041 aaccacgcac tctctagtag aaagggacta agtgacttgt ctctatggat tattatagca
     8101 tgattgtgag atttttcaag gattttgtga aagttttttg tttttcatat tttgtagaat
     8161 atgcttgatg ctaataccag aatccatgcc caccagagca actgtttcat agattagcaa
     8221 gtaaattagt ataaactcac caaaggttat gatagtaaag taaaagagca gtccgttacc
     8281 aactaaccat caaagtgaga aacggaaacg gtagctatag agtaacgata caatcaagat
     8341 taccagaggt gtaaagaaga gaagattgtt tatatagtgt aaaggggtca gaaacaacta
     8401 gcaagaacaa ctcataaagt ggccaataaa agaataatat gaccagatag taggggagat
     8461 gggaatagaa tctacgcatg ataatcacct cgttttaaaa aaacagacaa cttagatctc
     8521 ttgctatgat tattatagca tgtttaaaac aagaaagtaa atttgttgac aaagaagatt
     8581 tttcttttca ctagaatcat agttagtttt cttggtagaa atattttgat aataattaag
     8641 caagactatt gatattgatt attaagagtg tcacatttgt tgtaactaaa ataattacaa
     8701 caatagaggt ataaaaaatg aaactagcag ttattgcagc aaatggacaa gcggggaaag
     8761 caattgttga agaagcagtc aaacgaggac atgaagtaac ggctattgtt cgttctgaaa
     8821 acaaaagtca agctgagtct attattaaaa aagatttatt tgagttgaca aaagatgatc
     8881 ttactggatt tgatgctgtt atttcagcgt ttggtgctta tacaccagat acgctaccgc
     8941 tccacagcaa atcaatcgaa ctatttaatc agcttcttgc tggaacacag acacgttttc
     9001 tagttgtagg gggagcagga agtctttata tagatgaaac aaaaacgaca cgacttttag
     9061 atacgtctga ttttcctgaa gaatttaagt cactagcaaa agctcaagcg gatgaatttg
     9121 atcttcttcg tacaaaaaat aatctcaact ggacttttgt cagtcctgct gtagatttta
     9181 ttcccgatgg tgaaaaaaca ggaaactaca ttctagcagg agaaattttt actactaatg
     9241 gaaaaggaat aagccagatt agttatgcag attatgctat tggattggta gatgaacttg
     9301 aaaaaggtca tcatataaaa gaacgtatct ctttacttga aaaataataa ctatgagagt
     9361 attaatgttt gacagaaaat ttaaatcttg gtaaaatagg gattgtcgta aagacaaata
     9421 acttcttctt ggttacaggc atgccaacct gtcactcgga tgaagccaaa taaaaaggag
     9481 aaacatcatg gcaatctcaa aagagaaaaa aaatgaaatc attgcacaat atgcacgtca
     9541 cgaaggtgat acaggttcag tagaggttca agttgctgtc cttacttggg aaatcaacca
     9601 ccttaacgaa cacatcaaac aacacaaaaa agaccacgct acttaccgtg gattgatgaa
     9661 aaaaatcggt cgccgtcgta acttgcttgc atacttgcgt aaaaacgacg ttaaccgtta
     9721 ccgtgagttg atcaactctc taggacttcg tcgctaattc aagatacaaa ggccgtcaaa
     9781 agcacaaagc aaaaatagga aaattgacga agaaacttca gtttctagga gattttatct
     9841 tttttgccaa gtgcttaggc cgtgttcaat tgagcatatc ttgataataa agctactcta
     9901 aattgggtag ctttgttgcg ttgtcacctt acctcgctat actcaagtat aatcttcggt
     9961 tacggttcct agcactgtaa ggtaaaataa actagctttt ctcccttcgt ggagattttt
    10021 ttgtttcact gaaagtttcg tacgatcttc acctcgtccc ctagtctata aacgatttat
    10081 ctagcaagaa tcatgatgct aagggtgtca aaaatccgta tgaaaatagg gaaatgacac
    10141 agtgttcgat gagcacaagg agtttcatct ttttcactag gattttagcc cgggctaaaa
    10201 tcagctctct gacttcagag ggctttttta ttgaggtttt atcggtaaca attttggaga
    10261 ctacaaaaat ctcaaatggt atcagctaat tacaccataa aggtgcgcag ctactcggct
    10321 tttcaagccg agtagctgta tgcaagcccc ctagaagagc ccactcttta caaagtaaag
    10381 tatagtatgt tatactttac atggaagtag tcactgaatt ccagttagaa attactttgt
    10441 aactacgttt tgaggaggag taaaatgctt tcctacgttc gacattaccc actagcgata
    10501 gctaaattaa tgtgtttgtg ctctcctaaa atctgctgat ttattactga ctaatacagg
    10561 aggttttttt tatgggacag acaatcatat ctgctattgg tgtttatatt tccaccagta
    10621 tcgattattt aattatttta attattttat ttgcacagct atcacagaat aaacagaaat
    10681 ggcatattta tgcggggcaa tatctaggca caggcttact tgtaggggcg agtttagttg
    10741 ctgcttatgt cgttaatttc gtgcctgaag aatggatggt tggattgctt ggtttaatcc
    10801 ctatctattt agggattcgc tttgcaattg ttggagaaga tgcggaagaa gaagaggaag
    10861 aaattattca aagattagaa caaagcaagg caaatcaact gttttggaca gttacattgc
    10921 tgacaattgc gtctggcgga gataatttag gtatctatat accttatttt gcttcgttag
    10981 attggtcaca gaccctcgtg gccttgcttg tgtttgtaat cggcataatt atcttttgcg
    11041 agattagtag ggtgttatcc tctattccgt taatattcga gacaattgaa aaatacgagc
    11101 gaatcattgt gcccttagta ttcattctac ttggactata catcatgtat gaaaatggca
    11161 cgatagagac ttttctgatc gtgtagattt ttttgtttca ctaggatttt agcctgagct
    11221 caaatcagct ctctgatttt cagagggctt tttcattgag tataaatgga caatcttaaa
    11281 gttactctat tgtagagtgg cttttgattt gattagggga ttcttataaa tatagtaaaa
    11341 tgaaataaga ataggacaaa atcgatcagg acagtcaaat cgatttctaa aaatgtttta
    11401 gaagtagagg tgtactattc tagttccaat ctactatata aatgaaaacc ttagctgttt
    11461 ggccaaggtt catttcttct atgcaagttc ttctcttttc ttatctgggt tccagatgaa
    11521 gcttgcgata aagctaaaga tgatggttag gatagcgagg ataatagcaa ggatgagggc
    11581 agggatgcgg ataaaccacc agagtggatt tggtttttta tcattgtgcc attgtttcgt
    11641 ttcttcgtcc agacgttgga attctgtttg aatacgattg gcgactgttt caatgccttc
    11701 atcattcatt ttcttgatat ctgagatatc gattggattt ccaaagttca tatcgacacg
    11761 ttcacggcta atcaagccct tcaaagtcat gggaccggtg taggtaaccg gcatgatacg
    11821 gaccttggcc attttggcaa tcagtgctgc gccccccttg acatcgtttg agtggcggct
    11881 accacttgga aacatgatga gagagcggtc actttttttg agaacgttga taggatattt
    11941 gatggctgag gcgctgggat tttcacggtc gatgggaaag gcgccacaca tacgaatcca
    12001 ccaaccaaag atacggttgg taaagagttc tttttttgcc ataaagatga actgttttgg
    12061 cttggtcgca aaggccatat aaacaggatc ccaccaggta cggtgaggcg caactaaaat
    12121 ataattttca tcttgattag gaattttatc agtattatga tagtgagcat tgccattgat
    12181 ggaccataag agcaatacaa ctaatccacg caaataagta taaaacatgc gatctccttc
    12241 gattgttttc ttgttattat tataccttat caaaggaggg ctggcaaact tttcccttga
    12301 ctagatgcat atttgggatg aaattagaat tctgttaaaa aaaatgatat aatagaattt
    12361 atggataaaa ataagattat gggattaacc caaagagaag tcaaggaaag acaggctgag
    12421 ggtttggtca atgactttac cgcatcagcc agtaccagca cttggcaaat cgttaaacga
    12481 aatgtcttta ccctttttaa cgctttgaac tttgccattg ctttggccct tgcctttgtg
    12541 caggcttgga gcaatctggt cttctttgct gttatctgct ttaacgcttt ttctgggatt
    12601 gtgaccgagc tacgagccaa acacatggtg gacaagctca atctcatgac caaggaaaag
    12661 gtcaaaacca tccgtgatgg tcaggaagtt gctcttaatc ctgaagaatt agtgctagga
    12721 gatgtcattc gtttgtctgc aggagagcag attcctagtg atgccttggt tttggaaggc
    12781 tttgcggaag tcaatgaagc catgttaacg ggagaaagtg atttggtgca aaaggaagtt
    12841 gacggcttac ttttgtcagg aagtttccta gccagtgggt cagttttatc tcaagttcac
    12901 catgtcggtg cagacaacta tgctgccaaa ctcatgcttg aggctaagac cgttaaaccc
    12961 atcaactccc gtatcatgaa atcgctggac aagttggctg gttttactgg gaagattatc
    13021 attccctttg gtctggctct cttgctggaa gccttgcttt taaaaggcct gcctctcaag
    13081 tcatctgttg taaactcgtc gacagctctt ttgggaatgt tgcctaaggg aattgccctt
    13141 ttgaccatta cttcgctctt gactgcagtg attaagctag gtttgaaaaa ggtcttggtg
    13201 caggagatgt actctgttga gaccttggcg cgcgtggata tgctctgtct ggacaagacg
    13261 ggcaccatca cccaaggaaa gatgcaggtg gaggctgttc ttccactgac ggaaacttac
    13321 ggtgaagagg ctattgccag catcttgact agctacatgg cccatagtga ggataagaat
    13381 ccaactgccc aagccattcg ccagcgtttt gtgggagatg ttgcttatcc tatgatttcc
    13441 aatcttccct tctcgagcga ccgcaagtgg ggggctatgg agttagaagg cttggggaca
    13501 gttttcttag gggcacctga gatgttgctg gattctgaag tcccagaagc cagggaggcc
    13561 ttggagagag gatcacgtgt cttggtctta gctctcagtc aggagaaatt agaccatcac
    13621 aaaccacaga aaccatctga tattcaggct ctagccttgc tggaaatctt ggaccccatt
    13681 cgagagggag cagcagagac gctggactat ctccgttctc aggaggtggg actcaagatt
    13741 atctctggtg acaatccagt tacggtgtcc agcattgccc agaaggctgg ttttgcggac
    13801 tatcacagct atgtagattg ctcaaaaatc accgatgagg aattgatggc catggcggag
    13861 gagacagcta ttttcggacg tgtttcccct catcaaaaga aactcatcat ccaaacgttg
    13921 aaaaaagcgg gtcatacaac ggctatgaca ggggacgggg ttaatgatat cttggccctt
    13981 cgtgaggcgg attgttctat cgtgatggcg gagggggatc cagcaacccg tcagattgcc
    14041 aatctggttc tcttgaactc agactttaat gatgttcctg agattctctt cgagggtcgt
    14101 cgcgtggtca ataacattgc ccacatcgcc ccgattttct tgataaagac catctattcc
    14161 ttcctgttag cagtcatctg tattgccagt gctttactag gtcggtcaga gtggattttg
    14221 atttttccct tcattccgat ccagattacc atgattgacc agtttgtgga aggtttccca
    14281 ccattcgttc tgacttttga gcgaaatatc aaacctgtcg agccaaactt cctcagaaga
    14341 tccatgcttc gtgccctacc aagtgccctc atggtcgtgt ttggcgttct ttttgtgaaa
    14401 atctttggaa cgagtcaagg ttggtctgag ttagaaatct caactctcct ctattatctc
    14461 ttggggtcaa ttggtttctt atccgtattt agagcctgca tgccattcac tctatggcga
    14521 gtcctattga ttgtctggtc agtaggaggc ttcctagcca cagctctctt cccaagaatt
    14581 caaaaactgc ttgaaattgc aaccttaaca ggacaaacat tacctgttta tggtgtcatg
    14641 atgttggtct ttacagtgat tttcatcctg actagtcgct atcaagctag aaaataaaga
    14701 aagactgcaa tctgtggatt gcagtttttt atacgatgga tctatcgtag atctgatgtg
    14761 caaggcctac gtgtctatta tctatcggtg aacccaagag tgattctcaa gcctgcttgg
    14821 attgaggtaa tagattcaaa tatctgtagt tagactattt gaagtctgat gcaagaaata
    14881 attctcttcg aaaatatctt caaaccaggt ccgttctatc cacaatctca aagcggtact
    14941 ttgagcaact tgtggtcagc tccctagttt gatagtataa aaactgtcag ataaaggggt
    15001 ggcgaaattg tatctaaacg aacagaaacg tgatggtaag gcgtatagag ctcataggat
    15061 ggcaaggaaa gtctagaacc taaaaaagaa ctagataaat ccactaagtg tggttactct
    15121 agttcttttt cgtttattca acacccaaga tttctttaat atcatcaacg ctcagattgc
    15181 ttctgctttc ttgtccttca aggacggtgt tgaagagttc ctttttactt tcttggagtt
    15241 cttgtatttt ttcctctatg gtaccaagtg tgataaggcg atagacatcg acttgtttgg
    15301 tctggccaag gcggtggctt cggccgatgg cttgcatctc aactgctgga ttccaccaga
    15361 ggtcacagag gatgacggta tcagctcctg ttagattcag tcctgttcca cctgctttta
    15421 gggaaatgag gaagcagtct ttttcccctt gattgaaaag attgaccatt tcttgacgtt
    15481 tatctgaagg tgtttgtcct gttattttaa agtgagacat ttcttttttc tctagttctt
    15541 gctcaatgag atcaagcata gaggtgaatt gtgaaaagat aagtggtcgt gacccttttt
    15601 cacgaatggt gtctaggagc tcgaataagc tgtccatttt tccactatcc cctttgtagt
    15661 cttctaaaaa gagagcaggg gtattacaga tttgtctaag tcgggtcagt cctgctaaga
    15721 tttcaatttt atgacgttta atctcatagg cgctggctcc tgaaaccatt tcttgcatgc
    15781 gtcgaagttg agctagatag agcgtttttt gcgaactgct gagttcattg ctgtagaggt
    15841 gctcgctcag ttcaggcaat tctgtcagaa cttcgtcttt tttcctacgc agaacaaaag
    15901 gttgaatcag tttagcaacg agttgaggtg acaattttga aaattccttt ttacttggta
    15961 ggagacctgg taatactatc tggaaaatag accaaatctc ttcgagacgg ttttcaatag
    16021 gagttccaga tagggcatag caggttttga catcaaattc tcttaaagct tgtgctgttt
    16081 tggtctgact attttttatc atctgtgctt catctaggat gaggtagtcg taagactgct
    16141 tttgataatg ttcaaggtca gatcgaaaag atggatagct tgtaatagtg atagtagcag
    16201 atttttcaat ttgtttgata cgctcagttt tgctaccata ggctacttca acctgtttgt
    16261 gaggcacaaa ttttcggaat tcttccttcc aattataaag aaggctggct ggagctagga
    16321 taagagcttt ctggtctggt ttaaggttgg cttccagaag agtgatggtt tgcaaggttt
    16381 tccctagacc catgtcgtct gccaggattc ccccaaaatg ataatgatcc agcatactca
    16441 gccacttgac tccttctttt tgataggagc ggagtttggc cttgacttca taaggcttga
    16501 tatcaaattc ttcagggtgg gtcaggtcat aagccatctt tttgaaatca cgagaaaaat
    16561 tgacatgttc attgtctttg aaggtttcag aaaggctaaa ggcacgagat ttgtgcatct
    16621 tgatttttcc gtctgaaaat ttagcgcgaa gatcttggag actttgagca accttgagac
    16681 tttcatcgtc aaagactaga acctttcctt gcttggtttg gtagtggctt tcttgattcc
    16741 ataaagcttg gatagctttt tcaacctcat cttctgaaat catagaaaaa tcaaactgaa
    16801 ctgaaaggaa gctttcgtcg tcaaaaatgt caatgacagc aggatcttct actaagagtt
    16861 tttcaagcga ttcatctagt tgaacttgac ccagagtacg aaaacggggg agttctttta
    16921 ggaagaaatc aacgattttg attttggaaa gactatgaaa ttcctctttg aaaccagcag
    16981 aaagcagttg atgatagatt tttctagctt tgctagcttg gtaagtatag gggagggtta
    17041 ggagatcttg tttagaatgg acttgttttt ctccaaagga ccacaccata ttaagggcaa
    17101 tttcatttct agtcttggag aaggcaaagg tggggataaa gtcatggatt tgtaattcat
    17161 ctgggatact gataggaaca tagtttgaga tgatattaca gacttgcatg agttcagcct
    17221 tattttcttt tgaaaagata agaggagaat tttcttgata atgatagatc caagtagcta
    17281 atttatccaa aaagtaacgg tgttcttctt tgatgatgtg gaagtgattg tgtcgaatcc
    17341 aaagtttttc ttgaataatg aaaccaaaat aagctgtatt gatgatttca taatggttat
    17401 tagatttgac aactttaaaa atttcctctt ccgggataaa gggactatca tctaagaata
    17461 taagagggta ttcggctttt gaggttacat attggaagac atccaaagct tgaaaaagtg
    17521 ggacgaggtc gtttaaatag ctaacaggag tctctaaata gcgtccgtaa tctctagggt
    17581 taatgccata actgaagttg aaataagaat gttcatttct atcgataaaa tattttttaa
    17641 tatagaggag taggttttgg gatgcttgat taaactgatt caaggataat ctgattgtcc
    17701 cgattttctg tgaaacaaag taatcttcct tttggaaaat gagaaaaatg aagtgagcta
    17761 tatccttgat aacataggca cgaggagctt gttctacctg taattttaag gtccaggcta
    17821 ggctatgatt tcggatttcg acttgtccat gaagggcaag tgaaggcgcc gtagcttttt
    17881 cttctaccag ttcatcttgg agctcttcag atggcaaggt aggaatcagt tggctggcaa
    17941 aacttggttt atgactcgct ttaccaatgc gttcttgaat agcttggggg agactacgaa
    18001 aataaagatc catggcaacc cagtgtttac agactccctg attttggaaa tccttacatt
    18061 cgcaatgaaa gccagtcaaa tcgaagtgct ccatactggt caggatgttg ggctccagat
    18121 gcatggaaat accatcatag gtattggggt gcttaaaata ttccttattt tcagtatcaa
    18181 aatagttttt tatctgttgg aaaatagagc ggccatccat tctcatacga gcaggtagtc
    18241 tatcgggaac cgtcattgaa gtaacctctg ttctaatcat tcttttctct atcttatcag
    18301 aatttatagg aaaagaatag atttatctta cataaattgc atcttgatag ggattggaaa
    18361 catttgtagt tgcaagatag ttgtatgtaa tatcgacaat caattacaag gagattacga
    18421 ttccatagaa actatcaagt gaaaactgac ttatccataa cattctagct aaacttcttc
    18481 ttggtttggt aagtttttca tctggtgaac tagataggct gctataagta gtaaaattat
    18541 aagagcaaaa gcaacaactt ccagaccagc acttgttgca agaaatacga gagcaaggga
    18601 taggacagct gggataagta agttgataac attgatggat gattgaactg atcccattaa
    18661 ctcctcagga atgattccaa aaatcatggc ttgcaagcga ggactcaata ctcctgccga
    18721 gaaagcatca cccgcacttc ctagtaaaat aagtaaaaaa cttccacgta gaaaatctat
    18781 aacaatgaga gactccatca atagactcca ataaatattc aggcgaatag aaattttttt
    18841 agatagaaat ccactcagaa gtccacctaa aataacatga agaaggctta tcattattaa
    18901 aattgccaga ctttgccctg ttgacaaacc cataaaagga tggtgaatca gtagaatcgc
    18961 actgacaggc tctaccatca tcaaaacagc ttgactaatg gacaaaatcc aaagcaagac
    19021 catgacatct tccatagtca tcaataattt cattgactct ttcaaatgct ggaaaaagct
    19081 actcattcct acataaggag gaacttcgat tttttcttcc tcttttttca agcggtttcg
    19141 gataagtaga cttcctagaa aggcaaataa aaaggttaaa acatttacaa aagctagagt
    19201 agaaatgcta aacagtccta aaaatactcc tccgctgaga ttacctatca aacgtacaat
    19261 ggaactcgtg gactgcctaa aacccatagc ctccgtcata tcatcgttta ttagtcgtat
    19321 gtaaatcggt gtcagcatgt atcctgcaag aaaaccaatc gtatctgaaa tcaagttcat
    19381 gctgcaaata aagaaaacag aaaagagaga gaagtcggta cttgtcagga gcaaagtcac
    19441 tccagaataa aggaggacct tgataaagag gatagaaata tacttgctga ttcgattttt
    19501 ttgaaaatca gctataactc cagtaaaaag ttgcaagacc tgtggaatgg tttctgatag
    19561 gctaatcaaa aatatagcta agggagcaaa ggcataagaa gagacataat tgataaaagc
    19621 taagtaaaaa atagtatctc caaaacttga aatccactca tttactgtta gctgacgaaa
    19681 agctcgattt ttaagaaaaa tatgcatatt aatctccttt acttaattca aatgggaatg
    19741 tataaccgag taaagtccaa taaataccca gatttcccac accaaagtca aaataactgt
    19801 ttattccatc ttccccttga aattgtaata atctatcatt attacgataa gaacgagtca
    19861 ataagatttt ttttatgaac tgttcaacct tttgattttt attgtatatt gttgtttgca
    19921 ataaactact taaaccatgg caaaaactag ttcccattgc ttcatattgt tgcaccattt
    19981 caagttgtga tttatagatt atctcagagt atctttcttt atcaatcaaa caaagataca
    20041 atattaatcc tgaaactccg tcacaccaag aaagacctaa attatctaat ttagaaaagc
    20101 ttgaaagttt ctcttctagt aattcagata tcccgtcaga aaatttttgt aaatgatttt
    20161 gatagcgact atctccaaaa atatcagtat aggcttttaa tacataggca gcacctgaac
    20221 gtccgtgagc aaaattatta gaatatatat ctccattatc ctcggattct aataaactat
    20281 atgcatcatt tatattgttc ttgataaaat ttgctagttt tttatcatca aaaatggtac
    20341 aatatttcat caaactgagt aggataccag acttccctaa agcaaaatct aagttactaa
    20401 tattgtcata aacccgcatt aaatgatcga ctaatctctt acttatgtct attaaatatc
    20461 tctcctttgt tttttcatac ctatctagga ttccaaatag gaaacctgct ttcccaaata
    20521 gtagagagta accatgtaaa aaattagctg cttcataatt ttctaatttc gtaagccatt
    20581 ctttaacggt attttcatct tcctcaacat aatatttatt cataaaaaat aaaactcctc
    20641 caaaaccatg ttggaaagaa acaggactta cgaactcacc aaattcattt gacggaaaca
    20701 aacgaccaga tttgtccata gatttagcca gtaagtatga ttttatattc tcagcctcct
    20761 ctttaaaatt atatttttca aaataacttg aaaaatctgg agtatttaaa agaatgtcac
    20821 ttgtaacttg tttcaattgc tttatttttt ggattttttc tccctggctc atcattaata
    20881 aatcgtatag ccagtattct tgttgtttag ttattttatt gtctaatcta gctattttta
    20941 ttagatgaca tatttttata aaggccgata atcctgtttt ttgatcacct tttgaaaagg
    21001 ataaaaaatc acctgttaat aaagaaaatc caattagtgc taaactaaaa taatcttgtt
    21061 gaactgagct gatagttagg tcagtatctg gattaaccat cattggtgtt ttaactcgtc
    21121 ttaccttatc cttgatagga gtcattgtct ccaagtctat taatgttata tcaccttttt
    21181 tggtatatat aaaatttgta ggagctatat ctacaatttt atattcccag tttatggatg
    21241 taacttacta tattcacaat gttatccagt gttttttctc taatatttaa ggagtgttct
    21301 gtttctcgaa taaattcttc aaagtttaac ccgtcaactt gttcctgaac aagaaaataa
    21361 tcatccacga tataaaattc atcagttaaa ttagtagtat aacttttatc ggctaatttt
    21421 tttagcatgt gagcttcatt ttttatatca tcaagagctg tccattctcc ttcagcatca
    21481 taattcacaa aaggtcttga ctgcttgatg attacttttt gcccgtccga ttttctaatt
    21541 gcccgataaa catttccttt atttgatctc ttaataattt tttccatttt gtatttattt
    21601 attgcagagt ccttacttga aacttcacat gtggtttgaa aataaatcct tttttcttct
    21661 tctgaaaata aatccatttt ccagctagga agactaggga aattttgtct cttatcttct
    21721 acatagttct tccttttttc atctagcaat aaatagatga cttttttatt tttttcatca
    21781 taagcttgtt tttttaaaaa agccccatat ctataatgaa ctggagaatg cattccacat
    21841 tgatagtcag atagtatttt tggagcctta aattctgaca gtctattcgt aagattacaa
    21901 atcatactct tagcttcaga ttctgactta ggatatagag ttataaattt gttagcagta
    21961 gggctcattt ccctagggga attaattttt tttaattcct ctaaattttt aacaacttta
    22021 aagctacaat tatttagttg ggatagttta tacacaatct taaaaatatt tacagcgtct
    22081 tttatttggg agcttatgtg tattttccac ccttgtgcag gcatcttatc tgataaataa
    22141 tagtaattcc aaatatcacc ctgttggaaa tttttatcac attttaaaca ttctttctct
    22201 aataaatcca taacaaactc ctaattatta aaataggcta gagacacagc actagcctat
    22261 tccgtaagta aagctactta ttttatataa aatataacta gcgacctgta attaaacaag
    22321 taaaagaaca atacttaggg agacctgtga caatgatatc ttcctctgga agtagttcta
    22381 attcaaacaa tgtttgttcc atgactgtat cctcctgtta tgataaattc cagaaagcat
    22441 agagcaaatt cgtggttcgt ctgactaaat ttcttatctg aacaccacct tcaaatacaa
    22501 attttagtca aacttttatt ttttctaact ttctaattat attctaccat gtgtttttat
    22561 atgtcaagaa ttttctgaat aaactgttta ttttttattt tttgacattt ttgcaaattg
    22621 tttaaaatct ttcaattgga ttcacttatt actttaggac attgaaactt ctttcgccag
    22681 aggtgcttat attactggga agttgaagat tgaaatgtgg tataataaga ggtaatagag
    22741 ttttggaaag tgagagaaga tgatttcaaa gagattagaa ttggtagctt cctttgtgtc
    22801 acagggggct attttactag atgtgggaag tgaccatgct tatctgccta tcgagttggt
    22861 tgagagaggc caaatcaaaa gcgctattgc aggtgaggtg gtggaaggtc cctatcagtc
    22921 tgcggttaaa aatgttgagg ctcacggcct aaaggagaaa atccaagtcc gtttagccaa
    22981 tggcttggca gcttttgaag agactgacca agtgtctgtc attaccattg ctggcatggg
    23041 tggtcgtttg attgctagga ttttagaaga aggtttgggg aagttagcta atgtagagcg
    23101 tttgatcctc cagcccaata atcgtgaaga cgacttgcgt atctggctac aggatcatgg
    23161 attccagatt gtagcagaaa gcatcttaga agaagctgga aagttttatg agattttggt
    23221 ggtggaagca ggacaaatga agctatcagc cagtgatgtt cgctttggac cgttcttgtg
    23281 caaagaggtc agtccagtct ttgtccaaaa atggcaaaaa gaagctgtta agctagagtt
    23341 tgccctcgga caaatcccag acaaaaatct ggaagaacgt caagttctag tagataagat
    23401 tcaagccatc aaggaggtgc tccatgttag caagtgaagt gatccaagct tatgaagcct
    23461 tttgccctca ggaattttct atggagggag acagccgtgg tctgcaaatt ggcactttag
    23521 acaagggtat ccaaagggtc atggttgccc tcgatattcg tgaagagaca gtggcagagg
    23581 ccattgaaaa gggtgtggac ttgattatcg tcaagcacgc gcctatcttt cgtcctatca
    23641 aggacttgct tgccagccgt ccgcaaaatc agatttacat cgacctgatt aagcatgaca
    23701 tcgcagttta tgtcagccat accaatattg atatcgttga aaatgggctc aatgactggt
    23761 tttgtcagat gctagaaatc gaggagacga cttatctgca ggaaacaggt ccagaacgtg
    23821 gaattggacg tattgggaat attcagcctc agacctttgg agaattggcc caacatgtca
    23881 agcaagtctt tgacctagat agccttcgaa tggtgcatta tcaagagaat gatttgcaga
    23941 agcctatttc aagagtagca atttgtggtg gaagcgggca gtctttctat aaggatgctt
    24001 tggcaaaggg ggcagatgtc tatatcactg gtgatatcta ctaccatact gctcaggata
    24061 tgctgtctga tggcttgtta gcattggatc caggtcacta tatcgaagtg ctttttgtgg
    24121 aaaaaatcgc agcactcctt actcaatgga aagagaaaaa aggctgggaa ctagagattt
    24181 tacctagtca agcatcgacc aatcctttcc gtcatatcta gttagaaagt gaagacaatg
    24241 aaaaaagttg ccattattgg agcaggaatt gtgggagcaa cagctgccta ctacctctcg
    24301 agagaaagtg acctagaggt gaccgttttt gaccatgagc aaggtcaagc caccaaggcc
    24361 gcagcaggaa ttatcagtcc ttggttttcc aaacgccgta ataaagcctg gtacaagatg
    24421 gcgcgcttgg gggctgattt ttatgtggat ttattagctg atttagagaa atcaggacaa
    24481 gaaatcgact tttaccagcg ttcgggagtc tttctcttga aaaaggatga atccaatttg
    24541 gaagaacttt atcaactggc cctccagcgc agagaagaat ctcccttgat agggcaatta
    24601 gccattctga accaagcctc agctaatgaa ttattccctg gtttgcaggg atttgaccgc
    24661 ctgctctatg cttctggtgg agcgagagta gatggccaac tcttggtaac tcgtctgcta
    24721 gaagccagtc atgtcaagct ggtcaaagaa aaagtgactc tgacaccgtt agcatcaggc
    24781 taccagattg gtgaagagga gtttgagcag gttattttgg cgacgggagc ttggttgggg
    24841 gacatgttag aacccttggg ttatgaagta gatgttcgtc ctcaaaaagg acaactacga
    24901 gattatcagc tggtccaaga tatggaagct taccctgttg tcatgccaga aggggagtgg
    24961 gatttgattc cttttgcagg tgggaaattg tccttaggcg ctacccacga aaatgacatg
    25021 ggatttgatt tgacggtaga tgaaaccttg ctccaacaaa tggaggaggc caccttgact
    25081 cactatctga ttttggctga agctacttca aaatctgagc gtgttggaat ccgtgcctac
    25141 accagtgatt tctctccttt ctttgggcag gtgcctgact taactggtgt ctatgcagcc
    25201 agtggattag gttcatcagg cctcacaact ggtcctatta ttggttacca tttagctcaa
    25261 ctgatccaag acaaggagtt gaccttggac cctgaaaact acccaattga aaactatgtc
    25321 aaacgagtaa aaagcgaata atactcaatg aaaatcaaag aacaaactag gtaactagcc
    25381 gcgggttact caaagcactg ctttgaggtt gtggatagaa ctgacgaagt cagctcaaaa
    25441 cactgttttg aggttgtaga tagaactgac gaagtcagta accataccca tggcaaggcg
    25501 acgttgacgt ggtttgaatt ggattttcga agagtataag cattttactg aaattttatc
    25561 aggtagttta ggatggcaaa tgacattccc tgtcaaaaat ggtaaaataa gaaaaaataa
    25621 tctgagaatc gaggaaaaaa gatgcaagaa aagattttgg taactggtgg tgccggtttt
    25681 attggaaccc acactgttat tgaattgatc caagcaggcc atcaagttgt tgtggtggat
    25741 aatcttgtca atagcaatcg taagagttta gaagttgttg aaagaattac aggagttgag
    25801 attcctttct atgaggcaga tattcgtgac acagctaccc tcagagatat tttcaagcag
    25861 gaagaaccga ctggtgtcat tcactttgct ggtttgaagg ctgttggcga atcaacacgt
    25921 atccctcttg cctactatga caacaatatc gctggaactg tcagcctttt gaaagccatg
    25981 gaagaaaaca actgtaaaaa catcatcttc agttcttctg cgacagttta cggggatccg
    26041 cacacagtgc ccatcttgga agatttccca ctttcagtga ccaacccata cggtcgtacc
    26101 aagctcatgc tagaggaaat tttgaccgat atttacaaag cagactcaga atggaatgtt
    26161 gtcttgcttc gttactttaa cccaatcgga gcccatgaga gtggtgattt gggagaaaat
    26221 ccaaacggta ttccaaacaa tctcttgcca tatgtgactc aagtagccgt tggaaaatta
    26281 gagcaagtgc aagtgtttgg agacgattac gatacggaag atggaacagg tgttcgtgac
    26341 tatatccacg ttgtcgattt ggctaagggt cacgttgcag ctttgaaaaa aatccaaaaa
    26401 ggttcaggac taaacgttta taaccttgga actggtaaag gttactcagt tcttgaaatt
    26461 atccaaaaca tggaaaaagc ggtgggacgt cctattcctt accgtatcgt agaacgtcgc
    26521 ccaggtgata tcgctgcctg ctactcagac ccagcaaaag ctaaagcaga actcggttgg
    26581 gaagcagaac tcgacatcac ccaaatgtgt gaagacgcat ggcgttggca aagcaagcat
    26641 ccaaatggat ttgaagacta agatgatgat ttcaatcatc gtcccttgtt taaacgaaga
    26701 ggaagtactt cctctttttt atcaggctct ggaagcttta cttccagatt tggaaacaga
    26761 aatcgagtat gtctttgtcg atgatggatc aagtgatggg accttggaac tcttaaaggc
    26821 ctatcgggag caaaatccgg cagtccatta tatttctttc tctcgaaatt ttggcaaaga
    26881 agcagccctt tatgcaggct tgcaatatgc gacaggagat ttggtggtgg tgatggatgc
    26941 agacctccaa gatcctccta gtatgttgtt tgagatgaaa aatgtactag acaaaaatgt
    27001 agacttggac tgcgttggga cacggagaac tagtcgggag ggagaaccct tctttcgcag
    27061 tttctgtgct gttctctttt atcgcctcat gcaaaaaatc agcccagtag ctctgccgtc
    27121 gggtgtccgt gattttcgta tgatgagaag gtctgtagtc gatgccattt taagcttgac
    27181 cgagtccaat cgtttttcaa aggggctctt cgcctgggtg ggtttcaaaa cctactattt
    27241 ggactatcca aatgtcgaaa ggcaggctgg caagacaaat tggagtttta ggcaactctt
    27301 tttctactcc attgaaggga ttattaattt ttcagatttt cccttgatta tagcctttgt
    27361 agctggtctc ctatcttgtt ttctttctct gctgatgacc ttttttgttg tggttcggac
    27421 cctcattttg ggcaatccga catctggttg gacctctctg atggctgtta ttctctttct
    27481 tggaggtatt caactcttga ccattgggat tctcggcaag tatatcagta agatttattt
    27541 agaaaccaaa aaaagaccgc tttatcttat caaagaaaaa agttatcata gatcatgaaa
    27601 aagtaggagt tatctagcgc agtcactttt ttgtaattat aattcttttg gtctggaact
    27661 tgagtgattt ttaaaaaaat tagggatttg acatgatata aatgaactat gtggaataaa
    27721 tttactgcaa agacgataac ttaataaata aaaaattcag gagggttatt ttatgctaag
    27781 taaagaggag tatattgaag aaatcgggct tatagagaaa caaaattatg tagaggttga
    27841 actgtatcct ttagttgctg atataattaa tccgacttta aaaaatagtt tatcaaaaag
    27901 atatgtcttc ggaagaagaa agagtaatat ggggcaaata tattatggtc taagtaattt
    27961 tcctgatata gttattttgg ataagaatta tcaaaataaa gccagaaaaa gtatagaaat
    28021 tgaagaatgg aagaaacttc gaggatgcgt ggaaattaag agtttaaagc atgatttaat
    28081 tacagaggaa aaaatcaaat caaccatatc gaacagtttt gaacatataa ctggagagat
    28141 gggacaactt attggagacc ttttatggta taaaaaagta atttatacaa atggaattga
    28201 atggagattt ctaagtttag atgacaagga agagatagat aatacaattg ttcaagtagt
    28261 taacaaaaga atagaaacag aagaagcggg aaattctttt gattggtgga agaatattaa
    28321 agatttatcg ttcaattata cggatatata tttatctaaa gattgtatac aagagtggga
    28381 tgaatttgta aagaaagtaa aggaaataga atggtaggag tctattctca ttgagaaatt
    28441 tagattataa gtcgcagtaa gatttattta gagactaaaa aaagaccact ttatcttatc
    28501 aaagaaaaaa gtgaccttcc tgattttaca gaaaaaaata aagtgaaaag actataattt
    28561 tacatggaaa tgtgctaaac tagagggagt ggattatcgc cattgattta ggcttcctgg
    28621 tttccaatca gggcgcgagt tgggcaattt ttaacagcct ctaagatatc ctgactagga
    28681 gaaatttctt tttccagttg gtcagggtca tcgtaaaaac gcacgattcc attatcgtgg
    28741 taatcaaata aatcagaata agtttggcaa agcccacagg cgatacatcg ttcaggtata
    28801 agtgtgattt tcatgttcat atttatattg taataagaaa agtaaaaaaa aacaaggagt
    28861 aaggtatggc aaaagaaccg tggcaagaag atatctatga tcaagaagaa tcaagagcag
    28921 agcgtcggca tcgaaaccac ggaggggctg ataggatggc taatcgtatt ttgacgatcc
    28981 tagctagtat tttctttgta attgtggtgg tgatggtcat cgttctcatc tatctatcat
    29041 cgggggggag taatcgcaca gcagccttaa aaggctttca tgattctgat gcaagtgtag
    29101 tacaaatctc atcttcaagc agttctcagc ctgagcagag ttcagagcca gaatctactt
    29161 ctagtagttc agaagaagct gctaatcctg aaggaacgat taaagttctc gcaggagaag
    29221 gggaagcagc tattgccgct cgtgcaggaa tctccattgc tcagttagag gccttgaatc
    29281 ctgggcacat ggttacagga tcttggtttg ctaatccagg tgatgttata aaaataaaat
    29341 aggagccgat atgaaaacaa ttcaaattgc tattgatggt cctgcttcca gcggtaagag
    29401 tacggtcgca aagattattg ctaaggattt tggattcacc taccttgata caggagctat
    29461 gtatcgtgca gcgacctata tggctcttaa gaaccaatta ggagttgaag aagtcgaagc
    29521 ccttctagcc ttgttggacc agcatccaat cagctttgga cgttcagaaa ctggagacca
    29581 gcttgttttt gtaggagatg tggatattac ccatcctatc cgtgaaaatg aagtgaccaa
    29641 tcatgtttct gctattgcag caattcctga agtgcgtgag aaactggttt ctctccaaca
    29701 agaaattgcc cagcaaggcg ggattgtcat ggatggtcgc gatattggaa ctgttgtatt
    29761 gccacaagca gaattgaaaa ttttcctagt agcttctgtt gatgagagag cagagcgtcg
    29821 ttacaaggaa aatattgcca agggaattga aacagacctt gaaaccctaa aaaaggaaat
    29881 tgctgcgcgt gactacaagg atagtcatcg tgagacttct cctctcaaac aagcagagga
    29941 tgctgtctac cttgatacaa ctggtttgaa cattcaagaa gtagttgaaa aaatcaaagc
    30001 agaagctgaa aaaagaatgt aaatgtagaa aagccgatag attgatatcg gtttttttct
    30061 aaatttgtca aaatgctgat tttagggtat aatagttgct gttcgagaaa ttttgatttt
    30121 caaagaatag tgaatgatga taaggagaaa ccatgaacaa tttaccaaat tgtccaaaat
    30181 gtaactcaga gtatgtctac gaagacggtg ccctactggt ttgcccagag tgtgctcatg
    30241 agtggaatcc tgctgaagtt gcagaagtag aagaaggtct tgtcgctatc gatgccaacg
    30301 gaaataaatt gactgatggt gatacagtaa ctctcatcaa ggacttgaaa gtaaaaggtg
    30361 cgccaaaaga tttgaaacaa gggacgcgcg tgaaaaatat ccgcatcgta gaaggcgacc
    30421 acaatatcga ctgtaagatt gatggttttg gtgccatgaa acttaaatca gagtttgtga
    30481 ggaagattta agcatgtcaa aacactataa acttgtattt tatagccgta tcttcttgtt
    30541 tctagcggct tttacgggag tttatcttga aattactaag catggtggtt ttgggatgct
    30601 tctctattac acggttctgt ccaacctctt ggtaactatt tttacccttt atcttctaaa
    30661 ggttatgagc cgtgtaggtg aaaattggca aaggccaagt ctcttgcgct taaaaggtgg
    30721 ggtcaccatg agtatcatga ttacctgtgt gatttaccat ttcctcttgg cgcccattgc
    30781 gactaatttc tataccctag aaaatttcct ttgccactat atcgttccca tctggttttt
    30841 agcggatacc ctcttttttg acaaacaggg tcaatacaag atttgggatc cagcagtgtg
    30901 gaccatttta ccctttctgt atatgatgtt tgctcttttt aatggcttgg ttctaaaact
    30961 caatattcca aatgctaagg ataatccttt cccttacttc tttttgaatg tgaacaaggg
    31021 ttggaatgtt gtgtttaagt ggtgtctgat tatctttgtt gcctatatgg tagcaggatt
    31081 tattttctac tttatcaagc aaatcaagag aaagtcatcc taatactctt cgaaaatctc
    31141 ttcaaaccac gtcagcttcc atctgcaacc tcaaaacact gttttgaaca acctgcggct
    31201 agcttcctag tttgctcttt gattttcatt gagtataaga tacaagggat tcattttcga
    31261 atttaagaag gagtctacaa accaatgagg cttcttcttt tcttgcttat ttgataacta
    31321 tcaaaaaagt agaagattaa gagaaatata gaaagagatt tcatgaaaca atttttagaa
    31381 cgggccagca ttttggctct ctccctcgtt ttgattacct ccttttccat ttcgagtgcc
    31441 ctaccagcca tgtttgacta ttatcagggt tattctaagg aacaaattga gctcttggtg
    31501 agcttgcctt cctttggaat catgatgatg ttactgctaa atggtttctt agaaaaaata
    31561 tttcctgagc gcttacagat tagtttgggc ttgctgattt tatcattgag cggtacagct
    31621 cccttctggt accaagccta tccctttgtc tttggaacac ggcttctctt tggtttgggt
    31681 cttgggatga tcaatgccaa ggccatttct attatcagtg aacgctacca aggaaaaagg
    31741 cgaattcaga tgttagggct acgcgcttct gcagaggtcg ttggagcttc tctcattacc
    31801 ttggccgtcg gtcagttgtt ggcctttggt tggacagcta tctttctagc ctatagtgct
    31861 ggatttttgg tgctgcccct ttatctgctc tttgtccctt atggaaaatc aaagaaagaa
    31921 gtcaagaaaa gagcgaagga agcaagtcgt ttaactcgag aaatgaaagg cttgattttt
    31981 accttagcta tcgaagcggc agttgtagtt tgtaccaata cagctattac catccgtatt
    32041 ccaagtttga tggtggaaag aggattgggg gatgcccagt tatctagttt tgttcttagt
    32101 atcatgcagt tgatcgggat tgtggctggg gtgagttttt ctttcttgat ttctatcttt
    32161 aaagagaaac tgctcctctg gtctggtatt acctttggct tggggcaaat cgtgattgcc
    32221 ttgtcttcat ccttgtgggt ggtagtagca ggaagtgttc tggctggatt tgcctatagt
    32281 gtagtcttga cgacggtctt tcaacttgtc tctgaacgaa ttccagctaa actcctcaat
    32341 caagcaactt catttgctgt attaggctgt agtttcggag cctttacgac cccatttgtt
    32401 ctaggtgcaa ttggcttact aactcacaat gggatgttgg tctttagtat cttaggaggt
    32461 tggttgattg taatctctat ctttgtcatg tacctacttc agaagagagc ttaggattga
    32521 ttcctaagtt tttcttttga tactcaatga aaatcaaaga gcatagttga ttgagtttgg
    32581 aatagtacgc tgtagctgct aaaatatttc tagaaattaa tttgactttt ctaatagagt
    32641 tattcatatc ttatttcaat ctactataga aagctagccg caggttgctc aaaatagtgt
    32701 tttgaggttg cagatggaaa ctgacgtggt ttgaagagat tttcgaagag tatgagattt
    32761 ttatacccat acaatatttg ttttaggtcc ttgtttacag actaatttct tgataaaata
    32821 gaggttatga cgagatataa agcaactatt tcctatgatg gttatgcctt tgctggcttt
    32881 cagcgccagt ctcatgcgcg tagcgttcag gaagaaattg aaaaaacctt gaccagatta
    32941 aataaagggc aaaccattac tgttcacggt gctggtagga cagatagtgg ggttcatgcc
    33001 ctgggacagg tcattcattt tgacctgcct tatcagatgg atgaggagaa actccgtttt
    33061 gccttggata cccagtctcc tgaagatatt gatgtgattt cgattgagct tgtggcagat
    33121 gattttcatt gccgttatgc caaacatagc aagacctatg agtttattgt ggatagagga
    33181 cgtcccaaaa atcctatgcg ccgtcactat gccacccact ttccctaccc actcgatgtg
    33241 gaacgaatgc agattgcaat caaaaagcta gagggaaccc atgattttac cggttttaca
    33301 gcctctggga ctagtgtaga ggataaggtt cgcaccatca cagaagctag tttaatagtc
    33361 gatgagacag gacaattttt gacctttacc ttttcaggaa atggtttctt gtataaacag
    33421 attcgcaata tggtggggac tcttctcaaa atcggtaaca accgcatgcc agtagagcag
    33481 attgatctca tcttggagaa gaaggacagg caacttgcag gtcccactgc agcaccaaat
    33541 ggtttgtatt taaaggagat tcgttatgaa gaataatcgt attttagcac tttctggaaa
    33601 tgatattttt agtggtggtg gactgtcagc tgatttggct acctatacct tgaacggctt
    33661 gcatgggttt gtagcagtga cttgtttgac agccttgaca gaaaaaggat ttgaagtctt
    33721 tccaactgat gataccattt ttcaacatga attagatagc ttgcgtgatg tggaatttgg
    33781 gggaattaag attggtcttc tccctactgt cagtgtggct gagaaggcct tggactttat
    33841 caaacaacgc ccaggagtac ctgtggtgtt ggatcctgtc ttggtctgca aggaaacgca
    33901 tgatgtagct gtcagtgagc tctgccaaga gttgattcgc tttttccctt atgtcagtgt
    33961 gattacgcct aatctcccag aagcagaatt attatccggt caggaaatta aaaccttgga
    34021 agacatgaaa actgcagcgc agaaattgca tgatttagga gctccagcag tcattatcaa
    34081 gggaggcaat cgtcttagtc aggacaaggc ggtggatgtc ttttatgatg gacagacctt
    34141 tactatccta gaaaatccag ttatccaagg ccaaaatgct ggtgcaggtt gtacctttgc
    34201 ctctagcatt gccagtcact tgattaaagg tgataaactt ttgccagcag tagaaagctc
    34261 taaggctttc gtttatcgtg ctattgcaca agcagatcag tatggagtaa gacaatatga
    34321 agcaaacaaa aacaactaaa atcgcccttg tatccctatt aaccgccctt tctgtggttc
    34381 taggttattt cttaaaaatc ccaacaccta caggaattct aactctttta gatgctggtg
    34441 tcttctttgc ggccttttac tttggtagtc gtgaaggagc ggtagtcgga ggactagcaa
    34501 gtttcttgat tgacctctta tcaggctacc ctcagtggat gttctttagc ttggtcaacc
    34561 atggcttgca gggatttttc gcaggattta aaggaaaaag tcagtggtta ggccttattt
    34621 tagcaattat tgccatggta ggaggctacg ccttgggttc tactttgatg aatggctggg
    34681 cagcagccct cccagaaatt ctaccaaatt tcatgcaaaa tatggtaggg atgattgtag
    34741 gatttattct tagtcaaagt atcaagaaga ttaagtaata ctcttcgaaa atctcttcaa
    34801 accacgtcag cttccatctg caacctcaaa ccactgtttt gagcagcctg aggctagctt
    34861 tctagtttgc actttgattt tcattgagta taaagaggtt gagtaaaaag tatttcaaat
    34921 aagaaaaacg catagtatca ggtgttgaat gaactgcccc ccaaaagtta gacagaaaaa
    34981 atctaacttt tggggtgttt tattatgaaa ctaacttatg atgataaagt tcagatctat
    35041 gaacttagaa aacaaggata tagcttagag aagctttcaa ataaatttgg gataaacaat
    35101 tctaatctta ggtatatgat taaattgatt gatcgttacg gaatagagtt cgtcaaaaaa
    35161 ggaaaaaatc gttactattc tcctgattta aaacaagaaa tgattaataa agtcttacat
    35221 gaaggctgga ctaaagatag agtttctctt gaatacggtc tcccaagtcg tacgatactt
    35281 cttaactggc tagcacaata cag
//
LOCUS       DAVKMJ010000025        34482 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000025 DAVKMJ010000000
VERSION     DAVKMJ010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34482
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.025"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            636..1088
                     /locus_tag="VW348_001222"
     CDS             636..1088
                     /locus_tag="VW348_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU9746118.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            1107..2444
                     /locus_tag="VW348_001223"
     CDS             1107..2444
                     /locus_tag="VW348_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEU9746119.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2523..3407
                     /locus_tag="VW348_001224"
     CDS             2523..3407
                     /locus_tag="VW348_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9746120.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3407..4240
                     /locus_tag="VW348_001225"
     CDS             3407..4240
                     /locus_tag="VW348_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9746121.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4258..6351
                     /gene="nanB"
                     /locus_tag="VW348_001226"
     CDS             4258..6351
                     /gene="nanB"
                     /locus_tag="VW348_001226"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEU9746122.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIGEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWRYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6363..7466
                     /locus_tag="VW348_001227"
     CDS             6363..7466
                     /locus_tag="VW348_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU9746123.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQLSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7639..8337
                     /locus_tag="VW348_001228"
     CDS             7639..8337
                     /locus_tag="VW348_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEU9746124.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8356..9873
                     /locus_tag="VW348_001229"
     CDS             8356..9873
                     /locus_tag="VW348_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU9746125.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9998..11326
                     /locus_tag="VW348_001230"
     CDS             9998..11326
                     /locus_tag="VW348_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9746126.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11578..12444
                     /locus_tag="VW348_001231"
     CDS             11578..12444
                     /locus_tag="VW348_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9746127.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12460..13299
                     /locus_tag="VW348_001232"
     CDS             12460..13299
                     /locus_tag="VW348_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9746128.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13571..14023
                     /locus_tag="VW348_001233"
     CDS             13571..14023
                     /locus_tag="VW348_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEU9746129.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYDIDGD
                     KVFLVVQENVLNQAENDQFEYHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14156..14464
                     /locus_tag="VW348_001234"
     CDS             14156..14464
                     /locus_tag="VW348_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746130.1"
                     /translation="MDGQGITVDEMAWIIRGIVNGLIGRYIKLGTYAAKYGISMARSI
                     LSRAAATAAARVGLSTKISGWILRVAVNVADVYGNFANNIAAAWDAHDKIPNNGRINF
                     "
     gene            14474..14773
                     /locus_tag="VW348_001235"
     CDS             14474..14773
                     /locus_tag="VW348_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746131.1"
                     /translation="MKALCIFLLNMLAWTVLAMIIRGGLDGFDEHTWSTILIASLFGV
                     YDYKPIDKNRKKSKRKKKKEKIDLFMVGTYESFTDKKENSLQRKMMEEQTWHKKE"
     gene            14755..15399
                     /locus_tag="VW348_001236"
     CDS             14755..15399
                     /locus_tag="VW348_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEU9746132.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15568..16485
                     /locus_tag="VW348_001237"
     CDS             15568..16485
                     /locus_tag="VW348_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEU9746133.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16503..17387
                     /locus_tag="VW348_001238"
     CDS             16503..17387
                     /locus_tag="VW348_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEU9746134.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17403..18254)
                     /locus_tag="VW348_001239"
     CDS             complement(17403..18254)
                     /locus_tag="VW348_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEU9746135.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18454..20511
                     /gene="pbp2b"
                     /locus_tag="VW348_001240"
     CDS             18454..20511
                     /gene="pbp2b"
                     /locus_tag="VW348_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEU9746136.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            20522..21118
                     /gene="recR"
                     /locus_tag="VW348_001241"
     CDS             20522..21118
                     /gene="recR"
                     /locus_tag="VW348_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEU9746137.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21294..22337
                     /locus_tag="VW348_001242"
     CDS             21294..22337
                     /locus_tag="VW348_001242"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEU9746138.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22421..23794
                     /locus_tag="VW348_001243"
     CDS             22421..23794
                     /locus_tag="VW348_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEU9746139.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELGITDLVERKDSLTFKVNFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSVQLHNQMILSLSPDVLDIVIFYGEDIAQ
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAYDQILLKGSNSMNLAKLVE
                     RLENEAK"
     gene            23781..24392
                     /locus_tag="VW348_001244"
     CDS             23781..24392
                     /locus_tag="VW348_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9746140.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQGSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKFLDGQFQEN
                     QEIADLQFFAIDQLPALSEKRITKEQIEILWQVYQGQREQYLD"
     gene            24483..25187
                     /locus_tag="VW348_001245"
     CDS             24483..25187
                     /locus_tag="VW348_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEU9746141.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25406..26779
                     /gene="ftsA"
                     /locus_tag="VW348_001246"
     CDS             25406..26779
                     /gene="ftsA"
                     /locus_tag="VW348_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEU9746142.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26796..28055
                     /gene="ftsZ"
                     /locus_tag="VW348_001247"
     CDS             26796..28055
                     /gene="ftsZ"
                     /locus_tag="VW348_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEU9746143.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARTATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            28060..28731
                     /locus_tag="VW348_001248"
     CDS             28060..28731
                     /locus_tag="VW348_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEU9746144.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDIIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28741..29280
                     /locus_tag="VW348_001249"
     CDS             28741..29280
                     /locus_tag="VW348_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEU9746145.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29280..29543
                     /locus_tag="VW348_001250"
     CDS             29280..29543
                     /locus_tag="VW348_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEU9746146.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29540..30325
                     /locus_tag="VW348_001251"
     CDS             29540..30325
                     /locus_tag="VW348_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEU9746147.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30334..31122
                     /gene="divIVA"
                     /locus_tag="VW348_001252"
     CDS             30334..31122
                     /gene="divIVA"
                     /locus_tag="VW348_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEU9746148.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31470..34262
                     /locus_tag="VW348_001253"
     CDS             31470..34262
                     /locus_tag="VW348_001253"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEU9746149.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGETRKFVVAAELLTSLSEK
                     FGWVDVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEYVAQLFEVHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPTQDAVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYANFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
BASE COUNT        10628 a         6064 c         7491 g        10299 t
ORIGIN      
        1 gatttgaaac taaattccaa attagaaaaa gacttgaaat actaaaaaaa aaaagtatac
       61 tctaattgaa aacggtaaca aaactaattt agagaatgaa atatagagta tttctctctt
      121 aaaagttttt ggtgaaacga gatgtagaaa ggagatttag ccaaagagtc tattagtgct
      181 agaataatag attagaatta ttttagaaaa acgaagtgag cagcttataa attcaagtcc
      241 ccaaatagat tcatactagt atcttttgca aaaaataaag ggcgacttcc ttcatgaata
      301 tcaatttcat ctataaggaa ggtagctaat tgaactaact tatttattct gtttgtcgct
      361 agaaaaatca gacctccttg tgaagattga ggagatactg aatgaaaatc aaagaagaaa
      421 ctagcaagct agtagcagat tgcccaaaac accgctttga ggttgtagat aagactgacg
      481 tatataatcc aaggtgaagc gactgtggtt tgaagagatt ttcaaagagt ataggctaga
      541 gagtagtgtt tttatgtcct tctagtagaa aatgctagac agaagaatgg ggaacttgga
      601 taggaaaaat agattgagaa aggaggttag aagagatgat tattacaaaa attagccgtt
      661 taggaactta tgtgggagta aatccacatt ttgcaacatt aatagatttt ttagaaaaaa
      721 caggactaga aaatttaaca gaaggttcga ttgctatcga tggtaatcga ttgtttggga
      781 attgctttac ttatctagca gatggtcaag caggggcttt ctttgaaaca caccaaaaat
      841 atttggatat tcatttagtt ttggaaaacg aagaagccat ggctgttaca tcgccggaaa
      901 atgtaagcgt tacccaagaa tatgatgaag agaaagatat tgaattatac acagggaaag
      961 tggaacagtt ggttcatttg agagctggtg aatgcctcat cacttttcca gaagatttac
     1021 atcaacccaa ggttcgtata aatgatgaac ctgtgaaaaa agttgtcttt aaagttgcga
     1081 tttcttaatg tagaaagaga agaacgatga aaaaaatgag aaagttttta tgtctagctg
     1141 gaattgcgct agcggctgtt gccttggtag cttgttcagg aaaaaaagaa gctacaacta
     1201 gtactgaacc accaacagaa ttatctggtg agattacaat gtggcactcc tttactcaag
     1261 gaccccgttt agaaagtatt caaaaatcag cagatgcttt catgcaaaag catccaaaaa
     1321 cgaaaatcaa gattgaaaca ttttcttgga atgacttcta tactaaatgg actacaggtt
     1381 tagcaaatgg aaatgtgcca gatatcagta cagctcttcc taaccaagta atggaaatgg
     1441 tcaactcaga tgctttggtt ccgctaaatg attctatcaa gcgtattgga caagataaat
     1501 ttaacgaaac tgccttaaat gaagcaaaaa tcggagatga ttactactct gttcctcttt
     1561 attcacatgc acaagtcatg tgggttagaa cagatttgtt aaaagaacat aatattgagg
     1621 ttcctaaaac ttgggatcaa ctctatgaag cttctaaaaa attgaaagaa gctggagttt
     1681 atggcttgtc tgttccgttt ggaacaaatg acttaatggc aacacgtttc ttgaacttct
     1741 acgtacgtag tggtggagga agcctcttaa caaaagatct taaagcagac ttgacaagcc
     1801 aacttgctca agatggtatt aaatactggg ttaaattgta taaagaaatc tcacctcaag
     1861 attctttgaa ctttaatgtc cttcaacaag ctaccttgtt ctatcaagga aaaacagcat
     1921 ttgactttaa ctctggcttc catatcggag gaattaatgc caacagtcct caattgattg
     1981 attcgattga tgcttatcct attccaaaaa tcaaagagtc tgataaagac caaggaattg
     2041 aaacctcaaa cattccaatg gttgtttgga aaaattcaaa acatccagaa gttgctaaag
     2101 cattcttaga agcactttat aatgaagaag actacgttaa attccttgat tcaactccag
     2161 taggtatgtt gccaactatt aaggggatta gcgattctgc agcctataaa gaaaatgaaa
     2221 ctcgtaagaa atttaaacat gctgaagaag taattactga agctgttaaa aaaggtactg
     2281 ctattggtta tgaaaatgga ccaagtgtac aagctggtat gttaactaac caacacatta
     2341 ttgaacaaat gttccaagat atcattacaa atggaacaga tcctatgaaa gcagcaaaag
     2401 aagcagaaaa acaattaaac gatttatttg aggctgttca gtagatgtaa aagactagaa
     2461 aataggtggg ctagtgagct gaaaagctct agcccaatct tgtaaaagaa gggagaagga
     2521 gaatggttaa agaacgtaat ttaactcgct ggatatttgt tttgccagct atgattatcg
     2581 taggattact ctttgtttat ccgtttttct cgagtatttt ttatagcttt accaataagc
     2641 atttgattat gcctaattat aaatttgttg gtttggctaa ctataaagct gtgctgtcag
     2701 atcccaactt ctttaatgcg ttctttaatt caattaagtg gaccgttttc tcattagttg
     2761 gtcaagtttt agtagggttt gtattggctt tagctcttca cagagtacgc cacttcaaga
     2821 aattatatag gaccttattg attgttcctt gggcatttcc taccatcgtt attgccttct
     2881 cttggcagtg gattctaaac ggggtttatg gctacttacc taatctaatc gtaaaattag
     2941 gtttaatgga acatacacct gcatttttga cagatagtac atgggcattc ctatgtttgg
     3001 tgtttatcaa catttggttt ggagcaccaa tgattatggt taatgtgctt tcagctttgc
     3061 aaacagtacc agaagaacaa tttgaggctg ctaagataga tggtgcttca agttggcagg
     3121 tgttcaagtt tatcgtcttt ccacatatta aagtggttgt aggacttcta gttgttttga
     3181 gaactgtatg gatctttaat aactttgaca ttatctacct cattactggt ggtggaccag
     3241 ccaatgctac aacgacactt ccaatttttg cttacaacct gggttgggga actaaattgt
     3301 tgggtcgtgc ttcagcagtt acagtattgc tctttatctt cttggtggcg atttgcttta
     3361 tctactttgc tatcatcagt aagtgggaaa aggagggtag aaaataatga agaagaaatc
     3421 cagtatttat ttagatattc tctcacatgt acttttagtt ggtgcgacca tcgttgcaat
     3481 tttcccattg gtatggatta tcatatcttc tgtcaaaggg aaaggggaat taactcagta
     3541 tccaacacga ttttggcctg aacagtttac attagattat ttcactcatg ttatcaacga
     3601 tttgcacttc attgataaca ttcgaaacag tttaatcatt gccttggcta caaccctcat
     3661 tgcgattatt atttctgcta tggcagccta tggtattgtt cgattctttc ctaaattggg
     3721 agcaatcatg tcgagactac tcgtcattac ctacattttc ccaccaattt tgttagcaat
     3781 tccctattca attgccattg ctaaagttgg gttaacaaat agtttatttg gcttgatgat
     3841 ggtttatcta tcttttagtg ttccatatgc agtttggctc ttagttggat ttttccaaac
     3901 agttccaatt ggaattgaag aagcggctag aattgatggt gcaaataaat ttgttacgtt
     3961 ttataaggtt gtgctaccga ttgtagcacc aggtattgta gcaacagcta tttatacatt
     4021 tatcaatgct tggaatgaat tcctgtatgc cttgatttta attaacaata caggaaagat
     4081 gacagtagca gtagcccttc gttcacttaa tggttcagaa atactagact ggggagatat
     4141 gatggcagcg tctgttattg tagttcttcc atcaattatt ttcttctcta tcatccaaaa
     4201 taagattgca agtggattat cagaaggatc tgtgaagtag acgaaagaag gaaaaaaatg
     4261 aataaaagag gtctttattc aaaactagga atttctgttg taggcattag tcttttaatg
     4321 ggagtcccca ctttgattca tgcgaatgaa ttaaactatg gtcaactgtc catatctcct
     4381 atttttcaag gaggttcata tcaactgaac aataagagta tagatatcag ctctttgtta
     4441 ttagataaat tgtctggaga gagtcagaca gtagtaatga aatttaaagc agataaacca
     4501 aactctcttc aagctttgtt tggcctatct aatagtaaag caggctttaa aaataattac
     4561 ttttcaattt tcatgagaga ttctggtgag ataggtgtag aaataagaga cgcccaaaag
     4621 ggaataaatt atttattttc tagaccagct tcattatggg gaaagcataa aggacaggca
     4681 gttgaaaata cactagtatt tgtatctgat tctaaagata aaacatacac aatgtatgtt
     4741 aatggaatag aagtgttctc tgaaacagtt gatacatttt tgccaatttc aaatataaat
     4801 ggtatagata aggcaacact aggagctgtt aatcgtgaag gtaaggaaca ttacctcgca
     4861 aaaggaagta ttggtgaaat cagtctattt aacaaagcaa ttagtgatca ggaagtttca
     4921 aatattccct tgtcaaatcc atttcagtta attttccaat caggagattc tactcaagct
     4981 aactatttta gaataccgac actatataca ttaagtagtg gaagagttct atcaagtatt
     5041 gatgcacgtt atggtgggac tcatgattct aaaagtaaga ttaatattgc cacttcttat
     5101 agtgatgata atgggaaaac gtggagtgag ccaatttttg ctatgaagtt taatgactat
     5161 gaggagcagt tagtttactg gccacgagat aataaattaa agaatagtca aattagtgga
     5221 agtgcttcat tcatagattc atccattgtt gaagataaaa aatctgggaa aacgatatta
     5281 ctagctgatg ttatgcctgc gggtattgga aataataatg caaataaagc cgactcaggt
     5341 tttaaagaaa taaatggtca ttattattta aaactaaaga agaatggaga taacgatttc
     5401 cgttatacag ttagagaaaa tggtgtcgtt tatgatgaaa caactaataa acctacaaat
     5461 tatactataa atgataagta tgaagttttg gagggaggaa agtctttaac agtcgaacaa
     5521 tattcggttg attttgatag tggctcttta agagaaaggc ataatggaaa acaggttcct
     5581 atgaatgttt tctacaaaga ttcgttattt aaagtgactc ctactaatta tatagcaatg
     5641 acaactagtc agaatagagg agagagttgg gaacaattta agttgttgcc tccgttctta
     5701 ggagaaaaac ataatggaac ttacttgtgt cctggacaag gtttagcatt aaaatcaagt
     5761 aacagattga tttttgcaac atatactagt ggagaactaa cctatctcat ttcggatgat
     5821 agtggtcaaa catggaagaa atcctcagct tcaattccgt ttaaaaatgc aacagcagaa
     5881 gcacaaatgg ttgaactgag agatggtgtg attagaacat tctttagaac cactacaggt
     5941 aagatagctt atatgactag tagagattct ggagaaacat ggtcgaaagt ttcgtatatt
     6001 gatggaattc aacaaacttc atatggcaca caagtatctg caattaaata ctctcaatta
     6061 attgatggaa aagaagcagt cattttgagt acaccaaatt ctagaagtgg ccgtaaggga
     6121 ggccaattag ttgtcggttt ggtcaataaa gaagatgata gtattgattg gagataccac
     6181 tatgatattg atttgccttc gtatggttat gcctattctg cgattacaga attgccaaat
     6241 catcacatag gtgtactgtt tgaaaaatat gattcgtggt cgagaaatga attgcattta
     6301 agcaatgtag ttcagtatat agatttggaa attaatgatt taacaaaata aaggagaaaa
     6361 acatggttaa atacggtgtt gttggagcag ggtattttgg agctgaattg gctcgctaca
     6421 tgcaaaagaa tgatggagca gagattactc ttctctatga tccagataat gcagaggcga
     6481 ttgcagaaga attgggagca aaagtagcaa gttccttaga tgagttggtt tctagcgatg
     6541 aagtagattg tgttatcgtc gcaactccaa ataatcttca taaggaaccg gttattaagg
     6601 ctgcacagca tggtaaaaat gttttctgtg aaaaaccaat tgcgctttct tatcaagatt
     6661 gtcgcgagat ggtagatgcg tgtaaagaaa acaatgtaac ctttatggca ggacatatta
     6721 tgaatttctt taatggtgtt catcatgcaa aagaactcat taatcaagga gttatcggag
     6781 acgttctata ttgtcataca gctcgtaatg gttgggaaga acaacaactg tcagtatcat
     6841 ggaaaaaaat tcgtgaaaaa tcaggtggtc acttgtatca ccacatccat gaattggatt
     6901 gcgttcaatt ccttatgggg ggcatgcctg aaactgtaac catgacaggt ggaaatgtgg
     6961 cccatgaagg tgaacatttc ggtgatgaag atgatatgat ttttgtcaat atggaatttt
     7021 ctaataagcg ttttgccttg ttagaatggg gttcagctta tcgttggggt gaacattatg
     7081 tcttaatcca aggaagcaaa ggtgccatcc gcttagactt attcaactgt aaaggaactc
     7141 ttaagctaga tgggcaagaa agctatttct tgattcacga atcgcaagaa gaagatgatg
     7201 atcggactcg tatctatcat agtacagaga tggatggagc aattgcttat ggtaaaccag
     7261 gtaaacgtac tccattatgg ctatcatctg tcattgataa agaaatgcgc tatctgcatg
     7321 agattatgga aggagctcca gtatcagaag aatttgcaaa acttttgaca ggtgaagctg
     7381 ccctagaagc aattgctact gcagatgctt gtacccagtc tatgtttgaa gatcgcaaag
     7441 taaaattgtc agaaattgta aaataaattt tggtattctc ctattatagg tcgacttgct
     7501 cctctgaaag tacttttaga ggagctgttt gacttggcta gtttttgaaa ctgaaatcta
     7561 ttatactaca aactattgaa agcgttttaa ttttaaggta taataatctc atagaaataa
     7621 agaaaaggag gaaagaggat gccacagatt agcaaagaag ccttgattga gcaaatcaaa
     7681 gatggaatca tcgtttcttg tcaggctctt cctcatgaac cgctttatac agaagcggga
     7741 ggggtgattc ccttgctggt caaagcggct gagcaaggtg gagcagtcgg tatccgagca
     7801 aacagtgttc gcgatatcaa ggaaattaag gaagtcacta aacttccaat cattgggatt
     7861 atcaaacgtg attatccacc tcaggaaccc ttcatcacgg ctactatgaa agaagttgat
     7921 gaattggcag aactggacat cgaggtgatt gctctggatt gtaccaagcg tgaacgctac
     7981 gatggtttgg aaattcaaga gttcattcgt caggttaagg agaaatatcc taatcagctt
     8041 ttgatggctg atactagtat cttcgaagaa gggctagcag ctgtagaagc aggaattgac
     8101 tttgtcggaa caaccttatc aggctacaca tcctacagtc caaaagtaga cggtccagat
     8161 tttgaattga ttaagaaact ctgtgatgcc ggtgtagatg tcattgcaga aggaaaaatt
     8221 catacaccag aacaagccaa acaaatcctt gaatatggag tgcgaggcat cgttgttggt
     8281 ggcgccatta ctagaccaaa agagattaca gaacgcttcg ttgctagtct taaataagat
     8341 gtgaggggga gttttatgtt taaagtttta caaaaagttg gaaaagcttt tatgttacct
     8401 atagctatac ttcctgcagc aggtctactt ttggggattg gtggtgcact ttcaaaccca
     8461 accacgatag caacttatcc aatactagac aatagtattt ttcaatcaat attccaagta
     8521 atgagctctg caggagaggt tgtattcagt aatttgtcac tacttctctg tgtgggatta
     8581 tgtattggct tagcgaaacg agataaagga accgctgcgt tagcaggagt aactggttac
     8641 ttagttatga ctgcaacgat caaagctttg gtaaaacttt ttatggcaga aggatctgca
     8701 attgatactg gagttattgg agcattagtt gtcggaatag ttgccgtata tttgcacaac
     8761 cgatataaca atattcaatt accttccgct ttaggattct ttggaggttc acgcttcgtt
     8821 cctattgtta catcgttctc ttctatcttg attggctttg tcttctttgt tatttggcca
     8881 cctttccaac aacttcttgt ttctacaggt ggatatattt ctcaggcggg tccaattgga
     8941 acttttctat atggattttt aatgagactt tctggagcag taggcttaca tcatataatt
     9001 taccctatgt tttggtatac tgaacttggt ggtgttgaaa ctgttgcagg acaaacagtg
     9061 gttggagctc aaaaaatatt ttttgctcaa ttagccgatc cggcccattc tggattattt
     9121 acagaaggaa caaggttttt tgcaggtcgt ttctcaacaa tgatgttcgg tttaccggct
     9181 gcctgtttag cgatgtacca tagtgttcct aaaaatcgtc gtaaaaaata cgcgggtttg
     9241 ttttttggag ttgctttaac atcttttatt accggtatta cagaaccaat tgaatttatg
     9301 tttctattcg tcagtccggt tctatatgtt gttcacgcat tccttgatgg tgttagcttc
     9361 tttattgcag acgtcttaaa tatttcaata ggaaacacat tttcaggagg tgtaatcgat
     9421 ttcactttat ttggaatttt gcaggggaac gctaagacga attgggttct tcagattcca
     9481 attggactta tttggagtgt tttgtattat attattttta gatggttcat tactcaattc
     9541 aacgttctaa cgccaggacg aggagaagaa gtagattcta aagaaatttc tgaatccgca
     9601 gattcaactt caaatactgc agattattta aaacaggata gcctacaaat tatcagagcc
     9661 ttgggtggat caaataatat agaagatgta gatgcttgtg tgacacgttt acgtgtagct
     9721 gtaaaagaag ttaatcaagt tgataaagca cttttaaaac aaattggtgc agttgatgtc
     9781 ttagaagtga agggtggcat tcaagcaatc tatggagcaa aagcaatctt atataaaaat
     9841 agtattaatg aaattttagg tgtagatgat taagtactta ctgacttaat aaaaaacaga
     9901 ggagagtgat ggatgagtag gatgaaatga aatcgcatac aagaaataaa gaactcatta
     9961 tccaagttgg atacgcttat tacataggag aatacaaatg aaatttagaa aattagcttg
    10021 tacagtactt gcgggtgctg cggttcttgg tcttgctgct tgtggcaatt ctggcggaag
    10081 taaagatgct gccaaatcag gtggtgacgg tgccaaaaca gaaatcactt ggtgggcatt
    10141 cccagtattt acccaagaaa aaactggtga cggtgttgga acttatgaaa aatcaatcat
    10201 cgaagcgttt gaaaaagcaa acccagatat aaaagtgaaa ttggaaacca tcgacttcaa
    10261 gtcaggtcct gaaaaaatca caacagccat cgaagcagga acagctccag acgtactctt
    10321 tgatgcacca ggacgtatca tccaatacgg taaaaacggt aaattggctg agttgaatga
    10381 cctcttcaca gatgaatttg ttaaagatgt caacaatgaa aacatcgtac aagcaagtaa
    10441 agctggagac aaggcttata tgtatccgat tagttctgcc ccattctaca tggcaatgaa
    10501 caagaaaatg ttagaagatg ctggagtagc aaaccttgta aaagaaggtt ggacaactga
    10561 tgattttgaa aaagtattga aagcacttaa agacaagggt tacacaccag gttcattgtt
    10621 cagttctggt caagggggag accaaggaac acgtgccttt atctctaacc tttatagcgg
    10681 ttctgtaaca gatgaaaaag ttagcaaata tacaactgat gatcctaaat tcgtcaaagg
    10741 tcttgaaaaa gcaactagct ggattaaaga caatttgatc aataatggtt cacaatttga
    10801 cggtggggca gatatccaaa actttgccaa tggtcaaaca tcttacacaa tcctttgggc
    10861 accagctcaa aatggtatcc aagctaaact tttagaagca agtaaggtag aagtggtaga
    10921 agtaccattc ccatcagacg aaggtaagcc agctcttgaa taccttgtaa acgggtttgc
    10981 agtattcaac aataaagacg acaagaaagt cgctgcatct aagaaattca tccagtttat
    11041 cgcagatgac aaggagtggg gacctaaaga cgtagttcgt acaggtgctt tcccagtccg
    11101 tacttcattt ggaaaacttt atgaagacaa acgcatggaa acaatcagcg gctggactca
    11161 atactactca ccatactaca acactattga tggatttgct gaaatgagaa cactttggtt
    11221 cccaatgttg caatctgtat caaatggtga cgaaaaacca gcagatgctt tgaaagcctt
    11281 cactgaaaaa gcgaacgaaa caatcaaaaa agctatgaaa caatagtcct tagttattct
    11341 ataaaaagta gttttttaaa gaacctaaga gtgtataccc ccttttccct ctacacagat
    11401 agtgtaagaa aagggggctt ttgtttaaaa tgtaagaaac tgtcacgaaa ttaaaatgaa
    11461 gttcttacat aagcgaatca taaaaaattt cattttgatt ttaaaacagt tcaagaaagt
    11521 caaaaaatta ttctatttga aagagaggtg ccgactgtga aagtcaataa aatccgtatg
    11581 cgggaaacag tgatttccta cgctttccta gcaccagtat tattcttctt tgtcatcttt
    11641 gtgttggctc cgatggtgat gggcttcatt acaagtttct ttaactactc aatgactaaa
    11701 tttgagtttg taggcttgga taactatatc cgtatgttta aagatcctgt ctttacaaaa
    11761 tctctgatta acacagttat tttggttatt ggatctgtac cagttgttgt tctattctca
    11821 ctctttgtag catctcagac ctatcatcaa aatgtcattg ccagatcctt ctaccgtttc
    11881 gtcttcttcc ttcctgttgt aacgggtagt gttgccgtga cagttgtttg gaaatggatt
    11941 tatgacccac tatcagggat tctaaacttt gtccttaagt ccagccacat catcagccaa
    12001 aacatttctt ggttgggaga taaaaactgg gcattgatgg cgattatgat tattctcttg
    12061 accacttcag ttggtcagcc catcatcctt tatatcgctg ccatggggaa tattgacaat
    12121 tcactggttg aagcggcgcg tgttgatggt gcaactgagt ttcaagtttt ttggaagatt
    12181 aaatggccaa gccttcttcc aacaactctt tatattgcaa tcatcacaac aattaactca
    12241 ttccagtgtt ttgccttgat tcagcttttg acatctggtg gtccaaacta ctcaacaagt
    12301 accttgatgt actaccttta cgaaaaagcc ttccaattga cagaatacgg ctatgccaac
    12361 acaattggtg tcttcttggc agtcatgatt gctatcgtaa gctttgttca atttaaagta
    12421 cttggaaacg acgtagaata ctaaagaaag gagacagcta tgcaatctac agaaaaaaaa
    12481 ccattaacag cctttactgt tatttcaaca atcattttgc tcttgttgac tgtgctgttc
    12541 atctttccat tctactggat tttgacaggg gcattcaaat cacaacctga tacaattgtt
    12601 attcctcctc agtggttccc taaaatgcca accatggaaa acttccaaca actcatggtg
    12661 cagaaccctg ccttgcaatg gatgtggaac tcagtattta tctcattggt aaccatgttc
    12721 ttagtttgtg caacctcatc tctagcaggt tatgtattgg ctaaaaaacg tttctatggt
    12781 caacgcattc tatttgctat ctttatcgct gctatggcgc ttccaaaaca agttgtcctt
    12841 gtaccattgg tacgtatcgt caacttcatg ggaatccacg atactctctg ggcagttatc
    12901 ttgcctttga ttggatggcc attcggtgtc ttcctcatga aacaatttag tgaaaatatt
    12961 cctacagagt tgcttgaatc agctaaaatc gacggttgtg gtgagattcg taccttctgg
    13021 agtgtagcct tcccgattgt gaaaccaggg tttgcagccc ttgcaatctt taccttcatc
    13081 aatacttgga atgactactt catgcaattg gtaatgttga cttcacgtaa caatttgacc
    13141 atctcacttg gggttgcgac catgcaggct gaaatggcaa ccaactatgg tttgattatg
    13201 gcaggagctg cccttgctgc tgttccaatc gtcacagtct tcctagtctt ccaaaaatcc
    13261 ttcacacagg gtattactat gggagcggtc aaaggataat actctgagaa aatctcttca
    13321 aactacgtca gcgtcacctt gccatactta agtattgcct gcggttagct tcctagtttg
    13381 ttcttcaatt ttcattgagt ataggaaaat caatctatca agatacagaa gtatatttta
    13441 tagatttaga gaatatagag gttataagtg tctacaaaat ggagggtatg cagttacttt
    13501 atgaagtttt gtcagacact tataaactta agaatggttt tagttaacta tcagaaacga
    13561 aggaaagagt atgatttttg acgatttgaa aaacatcacc ttttacaaag ggattcatcc
    13621 taatttagac aaggctatcg actatctcta ccaacatcgt aaggattctt tcgaattagg
    13681 aaagtatgat attgatggag ataaagtctt tctagttgtt caggaaaatg tcctcaatca
    13741 agctgaaaat gatcaatttg agtatcataa gaactatgca gatttgcatt tgctggtaga
    13801 aggacatgaa tattcgagct acggttcacg tatcaaagac gaggcagtag cattcgacga
    13861 agcgagtgac attggctttg ttcattgtca tgaacactac ccactcttgt tgggttatca
    13921 caattttgcg attttcttcc caggtgagcc acatcagcca aatggttatg caggcatgga
    13981 agaaaaggtt cggaaatatc tctttaaaat tttgattgat taaaaatagg atgaattgtt
    14041 tttttgtaaa gctttgacaa tactctacca tgaaattgat ctttgtgagg tagggaaatg
    14101 agaataaaat atttaaaaat tggtatcttc taagtatgct gcaagagcta gtttcttgga
    14161 tggacaggga attacagttg atgagatggc ttggataatt aggggcattg tgaatggatt
    14221 gattggtaga tacataaaat taggtactta tgcagccaag tatggtatta gtatggcgcg
    14281 ttcgatctta agtagggcag ctgcaactgc agcagcaaga gtaggattat cgaccaagat
    14341 ttctggatgg attttacgag tagctgtgaa tgtagctgat gtatatggta attttgccaa
    14401 caatattgct gcagcttggg atgcacatga taaaattcct aacaatggtc gtataaactt
    14461 ttaaaatgcg agaatgaaag cactttgtat ttttttattg aatatgttag cttggacagt
    14521 gcttgcaatg ataattcgtg gagggctaga tggatttgat gagcatactt ggagtactat
    14581 tttaattgct tcgctgttcg gggtatatga ttataagccc atagataaaa atagaaaaaa
    14641 gtccaaaaga aaaaagaaaa aagaaaaaat agatttgttc atggtaggga cttatgaaag
    14701 ctttactgac aaaaaagaaa acagtttaca aagaaaaatg atggaggagc aaacatggca
    14761 caaaaaggag taagccttat caaggcagca tttgatacag acaactttct catgcgtttt
    14821 agtgagaaag tcttggacat cgtgacagcc aatcttcttt ttgtcgtctc ttgtttgccc
    14881 atcgtgacga ttggagtggc taaaatcagc ctctacgaga ccatgttcga agttaagaag
    14941 agcagacggg tgcctgtttt taaaatctat ctaagatctt tcaagcaaaa tctgaaacta
    15001 ggtcttcagc tgggtttaat ggagttagga attgtgtttc ttaccctttc agatctctat
    15061 cttttctggg gtcaaacagc tctgcccttc caattgctga aagccatttg tttaggtatt
    15121 ctgatttttc ttactatcgt gatgctggct agttacccta tcgcggcacg ttatgaccta
    15181 tcttggaaag aaattcttca aaaaggattg atgttggcta gttttaactt tccttggttc
    15241 ttcctcatgt tagccattct tgtcctcatt gtgatggttc tttatctgtc cgccttcagt
    15301 ctactcttag gtggctcagt cttcttactt tttgggtttg gactattggt ctttatccag
    15361 actggattga tggagaaaat tttcgcaaaa taccaatagg agccttattt ctgaaactac
    15421 tttcaaacgc tccaaacgct attctataag cgagaaacta aaatctaagt gtctataaga
    15481 tattgaaagc cttttcggta aagtgtatac taaagaagta aagaaaaatc tgctttagca
    15541 gaaaataaaa ataataggag aaaatctatg tcagatttga aaaaatacga aggtgtcatt
    15601 ccagccttct acgcatgtta tgatgaacaa ggagaagtaa gcccagaacg tacgcgtgcc
    15661 ttggttcaat acttcattga taaaggtgtt caaggtcttt atgtcaatgg ttcttctggt
    15721 gaatgtatct accaaagtgt tgaagaccgc aagttaatct tggaagaagt catggcggta
    15781 gccaaaggta aattgaccat cattgctcat gttgcctgca acaatactaa agatagtatg
    15841 gaacttgctc gccatgctga aagcttggga gtagatgcta ttgcaacgat tccaccaatt
    15901 tatttccgct tgccagaata ctcagttgcc aaatactgga acgatatcag ttctgcagct
    15961 ccaaacacag actacgtgat ttacaacatt cctcaattgg caggggttgc tttgactcca
    16021 agcctttaca cagaaatgtt gaaaaatcct cgtgttatcg gtgttaagaa ctcttctatg
    16081 ccagttcaag atatccaaac ctttgtcagc cttggtgggg aagaccatat cgtctttaat
    16141 ggtcctgatg agcagttcct aggaggacgc ctcatgggtg ctagggctgg tatcggtggt
    16201 acttatggtg ctatgccaga actcttcttg aaactcaatc agttgattgc ggataaggac
    16261 ctagaaacag cgcgtgaatt gcagtatgct atcaacgcaa tcattggtaa actcacttct
    16321 gctcatggaa atatgtacgg tgtcattaaa gaagtcttga aaatcaatga aggcttgaat
    16381 attggatctg ttcgttcacc attgacacca gtgactgaag aagatcgtcc agttgtagaa
    16441 gcggctgctg ccttgattcg tgaaaccaag gagcgcttcc tctaatctaa aaggaggtat
    16501 ttatgacata ctacgttgca attgatatcg gtggaaccaa catcaagtat ggtttggttg
    16561 atcaagaggg gcaacttctt gaatcgcatg aaatgccaac tgaggcgcat aagggtggac
    16621 ctcatatctt acaaaagacc aaagatatcg tagctagtta tttagaaaaa ggcccagtag
    16681 caggtgttgc catatcttct gctgggatgg tggatccgga taagggtgag attttctatg
    16741 ctgggcctca aatccctaac tacgcaggca cccagttcaa aaaggaaatc gaagaaagct
    16801 ttactattcc ttgtgagatt gaaaatgatg tcaactgtgc aggtcttgct gaggcagtat
    16861 ctggttcagg caagggagca agtgtgacac tttgcttgac cattggaacc ggtatcggtg
    16921 gttgcttgat tatggatagg aaagtcttcc atggttttag caattcagcc tgtgaagtcg
    16981 ggtatatgca tatgcaggat ggagcttttc aggatctcgc ttctacaaca gctttagtga
    17041 aatatgtagc tgaagcccat ggagaagatg ttgatcagtg gaatggccga cgtatcttta
    17101 aggaagctac tgaaggaaac aaaatctgca tggaaggtat tgaccgtatg gttgactatc
    17161 taggaaaagg tctggcaaat atttgttatg tggccaatcc agaagtggtt attcttggtg
    17221 gtggtatcat ggggcaagag gctatcctca aacctaagat ccgcacagcc ttgaaagagg
    17281 cattggtacc aagtttagca gaaaaaacac gattagaatt tgcccatcac caaaatacag
    17341 cagggatgtt gggtgcatat tatcatttta agacaaaaca atcctagttt ggctcagcca
    17401 aactaggatt ttcttacacg tttttgtcta cgatagccgt tgagtttttt attttcccag
    17461 tagctattaa agattttttc cttgctttcg cgattgattt ccaaaaagta ggcataaatc
    17521 aaatcgataa agaagagcat aggaagttga gcggatattc gttggatgta ggagggttgg
    17581 ctgtgggtgg ctacaagaac agtctctgta taggtctggc tatctttatt gggaacactt
    17641 gtaaagagta cagtctttgc ccccatctcc ttggcatcta atagactatc taaaatagaa
    17701 ggagttgagc ctgaaagtga gaaacccagt actagacaat tttcatccat gatgctggtt
    17761 gtccaggcaa agccgtcttg gtctgtcaaa gcttcgcaga ccacacctag tcgcataaaa
    17821 cgtaatttca tttcacgggc gacgaggcca gaactccctg ttccaaagaa gtagatacgc
    17881 tcagcatctt cgattagctg ggcaattcgc tctagttgga tttcgtcaat caagtcttgt
    17941 gtttgttccc tcatattgct ataacttctg aggactcgtt tggtcagtgg actatgcttg
    18001 gagacttggt tggcttgatt ttctgcctga tgttggtatt ggaaaataaa ttctcggtag
    18061 ccagtaaagc cacacttttt agcaaagcgg gtcaaagcag cttgagaaat atgtaatttt
    18121 tgggtgactt gttgagaaga taaatcatct gtaatcgttt cagcttgcaa aaaatagcga
    18181 gcgatttctt gctctaggtc tgtcatttct tcaaaatgtg aatcaatgat agttgcgata
    18241 tctggtttgt ccatagggaa agctccttta catgggtcat actggaagac tagatcaggg
    18301 aatagtcaca cttcattata acacataata taaggataga taaataaaaa cgcatctctg
    18361 ttttaaaaac gaaaaaatcg aaaaagcttc tctcttttcc ataattttct actcaaattg
    18421 tggtacaatt aagagtaaga ttttaaatta gaaatgagac tgatttgtat gagaaaattt
    18481 aacagccatt cgattccgat tcggcttaat ttattgtttt caatcgtcat tttactcttt
    18541 atgaccatta ttggtcgttt gttgtatatg caggttttga acaaggattt ttacgaaaaa
    18601 aagctagcct cagctagtca gaccaagatt acaagcagtt cagcccgtgg ggaaatttat
    18661 gatgctagtg gaaaaccttt ggtagaaaat acgttaaagc aggttgtttc ctttacgcgt
    18721 agcaataaaa tgacggctac agacttaaaa gaaacagcta aaaagttact gacttatgtg
    18781 agcatcagtt ctccaaattt gacagaacgc cagctggcgg attactattt ggctgatcct
    18841 gaaatctata aaaaaacagt ggaagctctc ccaagtgaga aacgcttgga ttcagatggc
    18901 aatcgtctat ccgaatcaga actgtataac aatgcggtcg atagtgtcca aacaagtcaa
    18961 ctaaactata cagaggatga aaagaaagaa atctatcttt ttagtcagtt aaatgctgtt
    19021 ggaaactttg cgacaggaac cattgctaca gatcctctaa atgattctca ggtggctgtt
    19081 attgcctcta tttcaaagga gatgcctggc attagtattt ctacttcttg ggatagaaag
    19141 gttttggaaa cttccctttc ttctatagtt gggagtgtat ccagtgaaaa agctggtctc
    19201 ccagcggaag aagcagaagc ctatcttaaa aaaggctatt ctctaaatga tcgtgtagga
    19261 acctcctatt tggaaaagca atatgaagag accttacaag gaaaacgctc ggtaaaagaa
    19321 atccatctgg ataaatatgg caatatggaa agcgtggata caattgagga aggtagtaag
    19381 ggaaacaata tcaaactgac cattgatttg gctttccaag atagcgtgga tgctttactg
    19441 aaaagttatt tcaattccga gctagaaaat ggtggagcca agtattctga aggtgtctat
    19501 gcagtcgccc ttaacccaaa aacaggtgcg gttttgtcta tgtcagggat taaacatgac
    19561 ttgaaaacgg gagagttgac gcctgattcc ttgggaacgg taaccaatgt ctttgttcca
    19621 ggttcggttg tcaaggcggc gaccatcagc tcaggttggg aaaatggagt cttgtcagga
    19681 aaccagacct tgacagacca gtccattgtc ttccaaggtt cagctcccat caattcttgg
    19741 tatactcagg cttacggttc attccctatc acagcggtcc aagctctgga gtattcatca
    19801 aatacctata tggtccaaac agccttaggt cttatggggc aaacctatca acccaatatg
    19861 tttgtcggca ccagcaatct agagtctgct atggagaaac tgcgttcaac ctttggcgaa
    19921 tatggcttgg gtactgcgac aggaattgac ctaccagatg aatctactgg atttgttccc
    19981 aaagagtata gctttgctaa ttacattact aatgcctttg ggcagtttga taactatacg
    20041 ccgatgcagt tggctcagta tgtagcaact attgcaaata atggtgttcg tgtggctcct
    20101 cgtattgttg aaggcattta tggtaataat gataagggag gactgggtga cttgattcag
    20161 caactgcaac cgacagagat gaataaggtc aatatatccg actccgatat gagcatcttg
    20221 caccaaggtt tttatcaggt tgcccatggt actagtggat tgacaactgg acgtgccttt
    20281 tcaaatggcg ccttggtatc cattagcgga aaaacaggta cagccgaaag ctatgtggca
    20341 gatggtcagc aagcaaccaa taccaatgcg gtggcctatg ccccatctga taatccccaa
    20401 atcgctgttg cagtggtctt tcctcataat accaatctaa caaatggtgt aggaccttcc
    20461 attgcgcgtg acattatcaa tctgtatcaa aaataccatc caatgaacta gaaaggaaat
    20521 tatgctttat ccaacaccta ttgccaagtt gattgacagt tattctaagt taccaggtat
    20581 cgggattaag acggctacgc gtctggcctt ttatacgatt gggatgtctg ctgatgatgt
    20641 caatgaattt gcaaaaaatc tcctttctgc taagagagaa ttgacatatt gttctatttg
    20701 tggacgtttg acagacgacg atccttgttc tatctgtact gatccgactc gtgaccagac
    20761 aacaatttta gttcttgagg atagtagaga tgtggcagcc atggaaaata tccaagaata
    20821 ccatggactc tatcatgtcc ttcatggcct catttctcct atgaatggta tcagtccgga
    20881 cgatatcaat ctcaagagcc ttatgactcg tcttatggat agtgaagttt cagaagtgat
    20941 tgtggcgact aatgctacag cggatggtga agcgacttcc atgtatcttt cacgtttgct
    21001 caagccggct ggtatcaagg ttacgcgtct agcacgaggt ctcgctgtgg gagcggacat
    21061 tgagtatgcg gacgaagtga cactcttacg agcgattgaa aatcggacag agttgtaagt
    21121 gtaggcaaat ttacgaactc cattcattta taaaaaatca aagaggctga aaatcgttcc
    21181 tatcggcctc tttttgtata gtgtgatgag taggatcagg ttcaagtttt aaaaaaccaa
    21241 gcaaatatga tatactaaag agcgagtatt ctagtagaat taggacaaat aatatgaaac
    21301 aaacgattat tcttttatat ggtggacgga gtgcggaacg cgaagtctct gtcctttcag
    21361 ctgagagtgt catgcgtgcg gtcaattacg accgtttcac agtcaagact ttctttatca
    21421 gtcagtcagg tgactttatc aaaacacagg aatttagtca tgctccgggg caagaagacc
    21481 gtctcatgac caatgaaacc attgattggg ataagaaagt tgcaccaagt gctatctacg
    21541 aagaaggtgc agtggtcttt ccagtccttc acgggccaat gggagaagat ggctctgttc
    21601 aaggattctt ggaagttttg aaaatgcctt acgttggttg caacattttg tcatcaagtc
    21661 ttgccatgga taaaatcacg actaagcgtg ttctggaatc tgctggtatt gcccaagttc
    21721 cttatgtggc tatcgttgaa ggcgatgatg tgactgctaa aatcgctgaa gtggaagaaa
    21781 aattggctta tccagtcttc actaagccgt caaacatggg gtctagtgtc ggtatttcta
    21841 agtctgaaaa ccaagaagaa ctccgtcaag ccttaaaact tgccttccga tatgacagcc
    21901 gtgtcttggt tgagcaagga gtgaatgccc gtgaaattga ggttggcctc ttgggtaact
    21961 acgatgtcaa gagcacgcta cctggagaag ttgtcaagga cgttgccttt tatgactacg
    22021 atgccaagta tattgataac aagattacta tggatattcc tgccaaaatc agtgatgatg
    22081 tggtggctgt catgcgtcaa aatgcagaaa cagccttccg tgccattggt ggccttggtc
    22141 tatctcgttg cgatttcttc tatacagata agggagagat ttttctcaac gagctcaata
    22201 ccatgccagg ttttacccag tggtctatgt acccactact ttgggacaat atggggatca
    22261 gctacccaga actaatcgag cgtttggttg accttgccaa ggaaagtttt gacaagcgcg
    22321 aagcgcattt gatataaaat gaaagagagg gtagaagcca gaaccatcac tgcacggtga
    22381 ctagagttct cggacttcag ccctttttaa aggagtagaa atgaaattaa caatccatga
    22441 aattgcccaa gttgttggag ccaaaaatga tatcagtatc tttgaggaca cccagttaga
    22501 aaaagctgag tttgatagtc gtttgattgg aactggagat ttatttgtgc cacttaaagg
    22561 tgcgcgtgat ggccatgact ttattgaaac agcctttgaa aatggtgcag cagtaacctt
    22621 gtctgagaaa gaggtctcaa atcatcctta cattctagta gatgatgttt tgacagcctt
    22681 tcaatcccta gcatcctact atcttgaaaa aacgactgtt gatgtctttg ctgttacagg
    22741 ttcaaatggc aagacaacga ctaaggatat gttggcgcat ttactgtcaa caagatacaa
    22801 gacctacaaa acacaaggca attacaataa tgagattggc cttccttaca cagttcttca
    22861 tatgcctgaa ggaacagaaa agttggtttt ggagatggga caggatcact tgggagatat
    22921 tcatctcttg tctgaattgg ctcgtccaaa aacagccatc gtgaccttgg ttggagaagc
    22981 tcatttggcc tttttcaaag atcgttctga gattgctaaa ggaaaaatgc aaattgcaga
    23041 cggaatggct tcaggttcct tgcttttagc gccggctgac cctatcgtag aggactattt
    23101 gccaactgat aaaaaggtgg ttcgttttgg tcaaggagca gagctgggaa ttaccgactt
    23161 ggttgagcgc aaagatagtc tgaccttcaa ggtcaatttc ttagagcaag cccttgattt
    23221 gccagtaact ggcaagtaca atgcgacaaa tgctatgatt gcatcctatg ttgccttgca
    23281 agaaggagtt tcagaggagc aaattcgttt ggccttccaa catcttgaat tgacgcgtaa
    23341 ccgtaccgag tggaagaaag cagccaatgg agcagatatc ctgtcagatg tttataatgc
    23401 caatccaact gctatgaaac tgattttaga gactttctct gccattccag ccaatgaagg
    23461 tggcaagaaa attgcagtgt tggcggatat gaaggagctt ggtgaccagt ctgttcaact
    23521 tcataatcag atgattttga gcctctcccc agatgtgctt gatatcgtta ttttctatgg
    23581 agaagatatt gctcagttgg ctcaattggc cagtcaaatg tttccaatcg gccacgttta
    23641 ctacttcaag aaaacagaag accaggatca atttgaagac ctagtcaagc aggttaagga
    23701 aagccttgga gcctatgacc aaatcttgct aaaaggttct aactctatga atctagccaa
    23761 attggtagaa cgtttagaaa atgaagccaa gtgattttgt caagtatctg caaagaatga
    23821 ttgcccttac agatactggc ttaaccttta caaaagatcc ttttgaccgt gagcgctacg
    23881 aggacttgcg aagtctgtta tctgaaatgt tgaatcaggg atcagacctg gatgcagaag
    23941 aagtagcaga agtcttgaaa ccaacttcag cttatgcgac tcccttaatg gacgtccgtg
    24001 cttggattgt tgaggatgag aagatttgtc tggttagggg acaaggagag gatagttggg
    24061 ctttgccagg tggctttggt gaagtcggct attctccaac tgaaaatatt ctcaaggaaa
    24121 ttgaagaaga aaccggtttt aaagccaaag ttgaaagact gctagctgtt tttgatacca
    24181 atcgtttcca actacagagt aaacaatatg caaagtttgt ttttgaatgt aagtttctcg
    24241 atggacaatt ccaagaaaat caagaaattg cagaccttca attttttgcc attgatcaac
    24301 tgccagcctt atctgaaaaa cgcattacca aggagcaaat cgagattctt tggcaggttt
    24361 atcaaggtca gagggagcaa tatcttgact aagaagatga ttatcgtatt tttaaatcca
    24421 tttttaacaa ctagcatggt ataataatat gcaggaaaat tttgaattat gaggaagact
    24481 agatgaattt atgggatatt ttctttacga ctcaggcaac cgagccgccc aaatttgacc
    24541 ttttttggta tgttagccta tttacgctct tagccttaac cttttataca gcccatcgct
    24601 atcgtgaaaa gaaggtttac caacgatttt tccaaatctt gcagactgtt cagttaatcc
    24661 ttctttatgg ttggtactgg gtcaatcata tgccactgtc agaaagccta cccttttacc
    24721 attgccgtat ggctatgttt gtggtactct tgcttcctgg tcagtccaaa tataaacaat
    24781 actttgcatt attgggaaca tttgggacat tagcagcctt tgtttatcca gtgccagatg
    24841 cttacccttt tccacatatc accattctat cctttatctt tggtcattta gcactcttgg
    24901 ggaactctct agtttatcta ttgagacagt ataatgcgcg attgctggat gtgaagggaa
    24961 tttttctcat gacctttgcc ctaaatgcct tgatttttgt ggtcaatttg gtgacaggtg
    25021 gcgattacgg atttttgaca aaaccgccat tggttgggga tcacggtcta gtagctaatt
    25081 atttacttgt ttcaattgtg ctggtagcta ctatcagttt gactaagaaa atcttagaat
    25141 tctttttagc tcaagaagca gaaaaaatga ttgcaaagga agcttaacac agagctttct
    25201 tttttgctct tagagagttt ttacaagcag cttataaaat aagaatttct gaatagacaa
    25261 actcaaaaaa tggctgggaa atttaggaaa aaagcaagca cgattaaatt ttttgtgtta
    25321 taatattttg tgaatagcta tgcctatgtt tagctatgga ataatacgaa gtgcgaaact
    25381 tggaagatag agaggaagcg atgtaatggc tagagaaggc ttttttacag gtctagatat
    25441 tggaacaagc tctgtcaagg tgcttgtggc cgagcagaga aatggtgaat taaatgtaat
    25501 tggcgtgagt aatgccaaaa gtaaaggtgt aaaggatgga attattgttg atattgatgc
    25561 agcagcaact gctatcaagt cagccatttc ccaagcggaa gaaaaggcag gcatttcgat
    25621 taaatcagtg aatgtcggct tgcctggtaa tcttttgcag gtagaaccaa ctcaggggat
    25681 gattccagta acatctgata ctaaggaaat tacggatcaa gatgttgaaa atgttgtcaa
    25741 atcagctttg acaaagagta tgacacctga ccgtgaagtc attaccttta ttcctgaaga
    25801 atttattgtg gatggtttcc aagggattcg tgacccacgt ggtatgatgg gggttcgcct
    25861 tgaaatgcgt ggtttgcttt atacaggacc tcgtactatc ttgcacaatt tgcgtaagac
    25921 ggttgagcgt gcaggtgttc aggttgaaaa tgttatcatt tcaccactag caatggttca
    25981 gtctgttttg aacgaagggg aacgtgaatt tggtgctaca gtgattgata tgggggcagg
    26041 tcaaacgact gtcgctacaa tccgtaatca agaactccag ttcacacata ttctccaaga
    26101 aggtggagat tatgtaacta aagatatctc caaggttttg aaaacctctc gcaaattagc
    26161 ggaaggcttg aaactgaatt acggggaagc ctatccgcct cttgcaagca aagaaacctt
    26221 ccaagtagag gttattggag aagtggaagc agtcgaagtg acggaagcct acttgtcaga
    26281 aattatttct gcacgaatca agcacatcct tgaacaaatc aagcaagaat tagatagaag
    26341 gcgtctattg gacctccctg gtggtattgt cttaatcggt gggaatgcca ttttaccagg
    26401 tatggttgag cttgctcagg aagtctttgg cgtccgtgtc aagctttatg ttccaaatca
    26461 agttggtatc cgtaatccag cctttgcgca tgtgattagt ttatcagaat ttgcgggtca
    26521 attaacagaa gttaatcttt tggctcaggg agcgataaaa ggtgagaatg acttaagtca
    26581 tcagccaatt agttttggtg ggatgctgca aaaaacagct cagtttgtac aatcaacgcc
    26641 tgttcaacca gctcctgctc cagaagtaga gccggtggcg cctacagaac caatggcgga
    26701 tttccaacaa gcttcacaaa ataaaccgaa attagcagat cgtttccgtg gcttgatcgg
    26761 aagcatgttt gacgaataaa gaggaaaaat aaattatgac attttcattt gatacagctg
    26821 ctgctcaagg ggcagtgatt aaagtaattg gtgtcggtgg aggtggtggc aatgccatca
    26881 accgtatggt cgacgaaggt gttacaggcg tagaatttat cgcagcaaac acagatgtac
    26941 aagcattgag tagtacaaaa gctgagactg ttattcagtt gggacctaaa ttgactcgtg
    27001 gtttgggtgc aggaggtcaa cctgaggttg gtcgtaaagc cgctgaagaa agcgaagaaa
    27061 cactgacgga agctattagt ggtgccgata tggtcttcat cactgctggt atgggaggag
    27121 gctctggaac tggagctgct cctgttattg ctcgtatcgc caaagattta ggtgcgctta
    27181 cagttggtgt tgtaacacgt ccctttggtt ttgaaggaag taagcgtgga caatttgctg
    27241 tagaaggaat caatcaactt cgtgagcatg tagacactct attgattatc tcaaacaaca
    27301 atttgcttga aattgttgat aagaaaacac cgcttttgga ggctcttagc gaagcggata
    27361 acgttcttcg tcaaggtgtt caagggatta ccgatttgat taccaatcca ggattgatta
    27421 accttgactt tgccgatgtg aaaacggtaa tggcaaacaa agggaatgct cttatgggta
    27481 ttggtatcgg tagtggagaa gaacgtgtgg tagaagcggc acgtaaggca atctattcac
    27541 cacttcttga aacaactatt gacggtgctg aggatgttat cgtcaacgtt actggtggtc
    27601 ttgacttaac cttgattgag gcagaagagg cttcacaaat tgtgaaccag gcagcaggtc
    27661 aaggagtgaa catctggctc ggtacttcaa ttgatgaaag tatgcgtgat gaaattcgtg
    27721 taacagttgt cgcaacgggt gttcgtcaag accgcgtaga aaaggttgtg gctccacaag
    27781 ctagaactgc tactaactac cgtgagacag tgaaaccagc tcattcacat ggctttgatc
    27841 gtcattttga tatggcagaa acagttgaat tgccaaaaca aaatccacgt cgtttggaac
    27901 caactcaggc atctgctttt ggtgattggg atcttcgccg tgaatcgatt gttcgtacaa
    27961 cagattcagt cgtttctcca gtcgagcgct ttgaagcccc aatttcacaa gatgaagatg
    28021 aattggatac acctccattt ttcaaaaatc gttaagtaaa tgaatgtaaa agaaaataca
    28081 gaacttgttt ttcgagaagt tgcagaggct agtctgagtg ctcatcgaga gagtggttcg
    28141 gtctctgtca ttgcagttac caagtatgta gatgtaccga cagcggaagc cttgcttccg
    28201 ctaggtgttc atcatatcgg tgaaaatcgt gtagataagt ttctggaaaa atatgaagct
    28261 ttaaaagatc gagatgtgac ttggcatttg attggtacct tgcaaagacg taaggtgaaa
    28321 gatatcattc aatacgttga ttatttccat gcattggact cagtaaagct agcaggggaa
    28381 attcaaaaaa gaagtgaccg agtcatcaag tgtttccttc aagtaaatat ttctaaagaa
    28441 gaaagcaaac acggtttttc gagagaggaa ctgctggaaa tcttgccaga gttagccaga
    28501 ctagataaga ttgaatatgt tggtttaatg acgatggcac cttttgaggc tagcagtgag
    28561 cagttgaaag agattttcaa ggcgacccaa gatttacaaa gagaaattca agagaaacaa
    28621 attccaaata tgcctatgac cgagttaagt atgggaatga gtcgtgatta taaagaagcg
    28681 attcaattcg gttccacttt tgttcgtata ggtacatcat tttttaagta ggagagaacc
    28741 atgtctttaa aagatagatt cgatagattt atagattatt ttacggagga tgaggattca
    28801 agtctccctt atgaaaaaag agatgagcct gtgtttactc cagtaaattc ttcacaggaa
    28861 ccggctctcc caatgaatca accttcacag tcggctggta caaaagagaa caatatcacc
    28921 agacttcatg caagacaaca ggaattggca aatcagagtc agcgtgcaac ggataaggtc
    28981 attatagatg ttcgttatcc tagaaaatat gaggatgcaa cagaaattgt tgatttattg
    29041 gcaggaaacg aaagtatctt gattgatttt cagtatatga cagaggtgca ggctcgtcgt
    29101 tgtttggact atttggatgg agcttgtcat gttttagctg gaaatttgaa aaaggtagct
    29161 tctaccatgt atttgttgac accagtgaat gttattgtaa atgttgaaga tatccgttta
    29221 ccagatgaag atcaacaggg tgagttcggt tttgatatga agcgaaatag agtacgataa
    29281 tgattttttt aattcgtatg atttataatg cagtggatat ttactccctg attttggtag
    29341 ccttcgctgt catgtcttgg tttccaggtg cctacgaatc cagtttaggt cgttggattg
    29401 tagcgttggt gaaaccagtg cttgctccct tgcaacgcct gcctttacag atagcgggtc
    29461 ttgatttatc tgtttgggtc gcgattgttt tggttcgatt tttaggagaa aacctagtgc
    29521 gttttctggc gatgatagga tgaataaagg gatttatcag catttctcca tagaagatcg
    29581 tccatttctt gacaagggaa tggaatggat aaagaaggta gaagatagct atgctccttt
    29641 tttaactcct tttatcaatc ctcatcagga gaagctatta aagattttgg ccaaaaccta
    29701 tggtcttgct tgtagcagta gtggggaatt cgtctcgagt gagtatgttc gagttttatt
    29761 atacccagat tatttccaac cagagttttc agattttgaa atatctctcc aggaaattgt
    29821 gtattccaat aaatttgaac atttaacgca tgctaagatt ttagggacag tcatcaatca
    29881 attagggatt gaacggaaac tttttggaga tatcctagta gatgaagaac gggcgcagat
    29941 tatgattaat cagcagtttc ttcttctctt tcaagatgga ctaaagaaaa ttggtcgtat
    30001 acctgtttcg ctggaggaac gtcctttcac cgagaaaata gataagctag aacagtatcg
    30061 agaactggat ttatctgtgt ctagttttcg attagatgtt cttttatcaa atgttttgaa
    30121 actatctagg aatcaagcaa accagttgat tgaaaagaaa cttgtccaag taaattatca
    30181 tgtggtagac aaatcagatt acactgttca agttggagac ttgattagtg tgagaaaatt
    30241 tggtcgcttg agattacttc aagataaggg acaaacgaaa aaagagaaga aaaaaataac
    30301 cgtccagtta ttattaagta agtgaggaat agaatgccaa ttacatcatt agaaataaag
    30361 gacaagactt ttggaactcg attcagaggt tttgatccag aagaagtcga tgaattttta
    30421 gatattgtgg ttcgtgatta cgaagatctt gtgcgtgcga atcatgataa aaatttgcgt
    30481 attaagagtt tagaagagcg tttgtcttac tttgatgaaa taaaagattc attgagccag
    30541 tctgtattga ttgctcagga tacagctgag agagtgaaac aggcggcgca tgaacgttca
    30601 aacaatatca ttcatcaagc agagcaagat gcgcaacgct tgttggaaga agctaaatat
    30661 aaggcaaacg agattcttcg tcaagcaact gataatgcta agaaagtcgc tgttgaaaca
    30721 gaagaattga agaacaagag ccgtgtcttc caccaacgtc tcaaatctac aattgagagt
    30781 cagttggcta ttgttgaatc ttcagattgg gaagatattc tccgtccaac agctacttat
    30841 cttcaaacca gtgatgaagc ctttaaagaa gtggttagcg aagtacttgg agaaccgatt
    30901 ccagctccaa ttgaagaaga accaattgat atgacacgtc agttctctca agcagaaatg
    30961 gaagaattac aagctcgtat tgaggtagcc gataaagaat tgtctgaatt tgaagctcag
    31021 attaaacagg aagtggaaac tccaactcct gtagtgagtc ctcaagttga agaagagcct
    31081 ctgctcatcc agttggccca atgtatgaag aaccagaagt agctccagtg catccgacag
    31141 gtccaacacc agctacagaa actgttgatt cagcaccagg atttgaagca ccgcaagaat
    31201 ccgttacaat tttataagaa acgatgtgag aacaatatct tatccttata tttccagcga
    31261 gcaggagatg gtgtgagtcc tgcattccct aacgataaga ttatcctctc aaaaactcaa
    31321 gtctgaatct agtaagattt gacgtttccc acgttacggg ataagaggga gaaagactaa
    31381 atctttttcc gaataaaggt ggtaccacga ttttcgtcct ttttggaagt cgtggttttt
    31441 aatttgttat tatttataaa ggagatacca tgaaactaaa agataccctt aatcttggga
    31501 aaacagcttt cccaatgcgt gcaggccttc cgaccaaaga gccagtttgg caaaaggaat
    31561 gggaagatgc aaaactttac caacgtcgtc aagaactaaa tgaagggaaa ccgcattttg
    31621 tcttgcatga tggccctcca tacgcaaacg gaaatatcca cgttggacat gccatgaatc
    31681 atatctcaaa agatatcatc attcgttcta agtctatgtc aggttttaac gcaccttata
    31741 tcccaggttg ggatactcat ggtctgccaa tcgagcaagt tttggcaaag caaggtgtga
    31801 agcgcaaaga aatggacttg gttgagtact tgaaactttg ccgtgaatac gctctttctc
    31861 aagtttataa acaacgtgat gatttcaagc gcttggggat gtcaggtgac tgggaaaatt
    31921 tatatgtgac tttaactcca gactacgaag cagcccaaat ccgtgtattt ggtgagatgg
    31981 ctaataaggg ttatatctac cgtggtgcta agccagttta ctggtcttgg tcatctgagt
    32041 cagcccttgc cgaagcggaa attgaatacc atgatttggt ttcaacttcc ctttactatg
    32101 ccaataaggt aaaagatggc aaaggtgttc tagatacaga tacttatatc gttgtttgga
    32161 caactactcc atttactatc acagcttctc gtggtttgac tgttggtgca gatattgatt
    32221 acgttttggt tcaacctgct ggtgaaactc gtaagtttgt cgttgctgca gaattgttga
    32281 ctagcttgtc tgagaaattt ggctgggttg atgttcaagt tttggcaact taccgtggtc
    32341 aagaactcaa ccacatcgta acagaacatc catgggatac agctgtagat gaattggtta
    32401 tccttggtga ccacgttaca actgactctg gtacaggtat tgtccataca gcccctggtt
    32461 ttggtgagga cgattacaat gttggtattg ctaataatct tgaagtcgca gtgactgttg
    32521 atgaacgtgg tatcatgatg aagaatgctg gtcctgaatt tgaaggtcaa ttctatgaaa
    32581 aggtagttcc aactgttatt gaaaaacttg gtaacctcct tcttgcccaa gaagaaatct
    32641 ctcactcata tccatttgac tggcgtacca agaaaccaat tatctggcgt gcagtaccac
    32701 agtggttcgc ctctgtttca aaattccgcc aagaaatctt ggatgctatt gataaagtta
    32761 aattccatac agaatggggt aaagtacgtc tatataatat gattcgtgac cgtggtgact
    32821 gggttatctc tcgtcaacgt gcttggggtg ttccacttcc aatcttctat gcagaagacg
    32881 gtacagctat catgacagct gagactatcg aatatgtggc tcaactcttt gaagtacatg
    32941 gttcaagcat ttggtgggaa cgtgatgcca aagacctctt gccagaagga tttacacatc
    33001 caggttctcc aaatggcgag ttcaaaaaag aaactgatat catggacgtt tggtttgact
    33061 caggttcatc atggaatggt gttttggtaa atcgtccaaa tctgacttat ccagctgacc
    33121 tttaccttga aggttctgac caataccgtg gttggttcaa ctcatcactc attacatctg
    33181 ttgccaacca tggcgtagca ccttacaaac aaatcttgtc acaaggtttt acccttgacg
    33241 gtaaaggtga gaagatgtct aaatctcttg gaaataccat tgctccaagc gatgttgaaa
    33301 aacaatttgg tgctgaaatc ttgcgtctct gggtaacaag tgttgactca agcaatgacg
    33361 tgcgtatctc tatggatatc ttgagccaag tctctgaaac ttaccgtaag attcgtaata
    33421 ctcttcgttt cttgattgcc aatacatctg actttaaccc aactcaagat gcagtcgctt
    33481 acgatgaact tcgttcagtt gataagtaca tgaccattcg ctttaaccag cttgtcaaga
    33541 ccattcgtga tgcctatgca aactttgaat tcttgacaat ctacaaggcc ttggtgaact
    33601 ttatcaacgt tgatttatca gccttttacc ttgattttgc taaagatgtt gtttacatcg
    33661 aaggtgctaa atcactggaa cgtcgtcaaa tgcagactgt cttctatgat attcttgtca
    33721 aaatcaccaa actcttgaca ccaatccttc ctcacactgc ggaagaaatc tggtcatatc
    33781 ttgagtttga aacagaagac ttcgtccaat tgtcagaatt accagaagtt caaacttttg
    33841 ctaaccaaga agaaatcttg gatacatggg cagccttcat ggactttcgt ggacaagcac
    33901 aaaaagcctt ggaagaagct cgtaatgcaa aagttatcgg taaatcactt gaagcacact
    33961 tgacagttta tccaaatgaa gtggtgaaaa ctctactcga agcagtaaat agcaatgtgg
    34021 ctcaactttt gatcgtgtct gagttgacca tcgcagaagg accagctccg gaagctgccc
    34081 ttagcttcga agatgtagcc ttcacagttg aacgtgctgc tggtgaagta tgtgaccgtt
    34141 gccgtcgtat tgacccaaca acagcagaac gtagctacca ggcagttatc tgtgaccact
    34201 gtgcaagcat cgtagaagaa aactttgcgg aagcagtcgc agaaggattt gaagagaaat
    34261 aagattgaaa agtctaggca aaattcaatt tgagaagaaa agacaactaa ttttatagtc
    34321 tattaaacgc attgtatcac gtttttgaac acctgatatg atgcgttttt tatttatttt
    34381 aaaaatttgc gaggtatgac tttttatact caacaagaat caaagagaaa cttagcaagc
    34441 taacagtagt aagataaaat aggaatttga tattagggat aa
//
LOCUS       DAVKMJ010000026        34260 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000026 DAVKMJ010000000
VERSION     DAVKMJ010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34260
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.026"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..293)
                     /locus_tag="VW348_001254"
     CDS             complement(<1..293)
                     /locus_tag="VW348_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9746150.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYQCSKMMVAETPLVK"
     gene            complement(475..711)
                     /locus_tag="VW348_001255"
     CDS             complement(475..711)
                     /locus_tag="VW348_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9746151.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(724..1197)
                     /locus_tag="VW348_001256"
     CDS             complement(724..1197)
                     /locus_tag="VW348_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746152.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(1215..1400)
                     /gene="briC"
                     /locus_tag="VW348_001257"
     CDS             complement(1215..1400)
                     /gene="briC"
                     /locus_tag="VW348_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEU9746153.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(1559..2326)
                     /locus_tag="VW348_001258"
     CDS             complement(1559..2326)
                     /locus_tag="VW348_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEU9746154.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKHAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(2323..3189)
                     /locus_tag="VW348_001259"
     CDS             complement(2323..3189)
                     /locus_tag="VW348_001259"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEU9746155.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(3226..4593)
                     /gene="accC"
                     /locus_tag="VW348_001260"
     CDS             complement(3226..4593)
                     /gene="accC"
                     /locus_tag="VW348_001260"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEU9746156.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(4605..5027)
                     /gene="fabZ"
                     /locus_tag="VW348_001261"
     CDS             complement(4605..5027)
                     /gene="fabZ"
                     /locus_tag="VW348_001261"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEU9746157.1"
                     /translation="MIDIQEIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(5024..5509)
                     /locus_tag="VW348_001262"
     CDS             complement(5024..5509)
                     /locus_tag="VW348_001262"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEU9746158.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(5512..6747)
                     /gene="fabF"
                     /locus_tag="VW348_001263"
     CDS             complement(5512..6747)
                     /gene="fabF"
                     /locus_tag="VW348_001263"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEU9746159.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(6769..7500)
                     /gene="fabG"
                     /locus_tag="VW348_001264"
     CDS             complement(6769..7500)
                     /gene="fabG"
                     /locus_tag="VW348_001264"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEU9746160.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(7534..8454)
                     /gene="fabD"
                     /locus_tag="VW348_001265"
     CDS             complement(7534..8454)
                     /gene="fabD"
                     /locus_tag="VW348_001265"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEU9746161.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(8447..9421)
                     /gene="fabK"
                     /locus_tag="VW348_001266"
     CDS             complement(8447..9421)
                     /gene="fabK"
                     /locus_tag="VW348_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEU9746162.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     VSIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWTGVVRND"
     gene            complement(9540..9764)
                     /locus_tag="VW348_001267"
     CDS             complement(9540..9764)
                     /locus_tag="VW348_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEU9746163.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(9824..10798)
                     /locus_tag="VW348_001268"
     CDS             complement(9824..10798)
                     /locus_tag="VW348_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEU9746164.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(10798..11232)
                     /locus_tag="VW348_001269"
     CDS             complement(10798..11232)
                     /locus_tag="VW348_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU9746165.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(11326..12111)
                     /locus_tag="VW348_001270"
     CDS             complement(11326..12111)
                     /locus_tag="VW348_001270"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEU9746166.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            12480..13844
                     /locus_tag="VW348_001271"
     CDS             12480..13844
                     /locus_tag="VW348_001271"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEU9746167.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            13847..14218
                     /locus_tag="VW348_001272"
     CDS             13847..14218
                     /locus_tag="VW348_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEU9746168.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            14432..15706
                     /gene="serS"
                     /locus_tag="VW348_001273"
     CDS             14432..15706
                     /gene="serS"
                     /locus_tag="VW348_001273"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEU9746169.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILIK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDASVTIPEALRPYMGGAEVIKP"
     gene            complement(15731..16630)
                     /locus_tag="VW348_001274"
     CDS             complement(15731..16630)
                     /locus_tag="VW348_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEU9746170.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(16740..17288)
                     /locus_tag="VW348_001275"
     CDS             complement(16740..17288)
                     /locus_tag="VW348_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEU9746171.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(17506..18828)
                     /locus_tag="VW348_001276"
     CDS             complement(17506..18828)
                     /locus_tag="VW348_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEU9746172.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTIRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSIAESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMAIIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(18919..19007)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(19171..21507)
                     /locus_tag="VW348_001277"
     CDS             complement(19171..21507)
                     /locus_tag="VW348_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEU9746173.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRKVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(21611..22159)
                     /locus_tag="VW348_001278"
     CDS             complement(21611..22159)
                     /locus_tag="VW348_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEU9746174.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQIYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(22156..22458)
                     /gene="zapA"
                     /locus_tag="VW348_001279"
     CDS             complement(22156..22458)
                     /gene="zapA"
                     /locus_tag="VW348_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEU9746175.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            22545..23429
                     /locus_tag="VW348_001280"
     CDS             22545..23429
                     /locus_tag="VW348_001280"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEU9746176.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVASFV
                     TPDQHAFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQETNRFSNPISNPISLEE
                     KAEGKYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQG
                     LNFCAKLHFKNTEKAKNA"
     gene            23441..24055
                     /gene="lepB"
                     /locus_tag="VW348_001281"
     CDS             23441..24055
                     /gene="lepB"
                     /locus_tag="VW348_001281"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEU9746177.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            24183..26549
                     /locus_tag="VW348_001282"
     CDS             24183..26549
                     /locus_tag="VW348_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEU9746178.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLKTIQKHITTIEKELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSSISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(26597..27880)
                     /locus_tag="VW348_001283"
     CDS             complement(26597..27880)
                     /locus_tag="VW348_001283"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEU9746179.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(28724..29860)
                     /locus_tag="VW348_001284"
     CDS             complement(28724..29860)
                     /locus_tag="VW348_001284"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HEU9746180.1"
                     /translation="MKHSVHFGAGNIGRGFIGEILFKNGFHIDFVDVNNQIIHALNEK
                     GKYEIEIAQKGQSRIEVTNVAGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELL
                     AKGIEARRVAGNTQVLDVMACENMIGGSQFLYQEVKKYLSPEGLTFADNYIGFPNAAV
                     DRIVPAQSHEDSLFVVVEPFNEWVVETKRLKNPDLRLKDVHYEEDLEPFIERKLFSVN
                     SGHATSAYIGAHYGAKTILEALQNPNIKSRIESVLAEIRSLLIAKWNFDKKELENYHK
                     VIIERFENPFIVDEVSRVARTPIRKLGYNERFIRPIRELKELSLSYKNLLKTVGYAFD
                     YRDVNDEESIRLGELLAKQSVKDVVIQVTGLDDQELIEQIVEYI"
     gene            complement(29922..30359)
                     /locus_tag="VW348_001285"
     CDS             complement(29922..30359)
                     /locus_tag="VW348_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEU9746181.1"
                     /translation="MKLEKHLIKLNKQFSNKEEAICYCGQVLYEGGYVNEDYIEAMIE
                     RDKELSVYMGNFIAIPHGTDAAKKDVLKSGITVVQVPRGVDFGNVSNPQVATVLFGIA
                     GIGNEHLEIIQKISIFCADVDNVLKLADAQSKEEVLRLFDAVE"
     gene            complement(30361..32316)
                     /locus_tag="VW348_001286"
     CDS             complement(30361..32316)
                     /locus_tag="VW348_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU9746182.1"
                     /translation="MLLTKREEQLLKAFLHVGKLSMQDMTEILQVSSRTIYRTLSDLT
                     DSMEQYGIEITKHGKYYILTGELDDLPTELEVLVEYSPQERQELITYRLLTESGFVTN
                     EALQECTKVSNVTIIQDISDIDKRLLDFDLKIERQKGYRISGDSVGKRRFLAILLTNC
                     ISVADFSTGNFGSFDILEADRTRLASQIVNKQLSGFPDMDARMKMFFAILLSLIGQEQ
                     NIENSPNTSKQALEISQKIFQAYSKQTAQFYSIQEIIYFASILDELIIKRQDNPLFTE
                     KFDGEFFYNISNLIDTVSMYTKIDFFKDKVLFNFLFHHIRLSLGVPILFQGENLPESV
                     QILVERNKFLYTVISLLVNDIFPKYLHTEYEYGMIALHFISSLGRSPEIYPVRVLLLT
                     DERRVTRDLLVSKIKSVAPFVELIDIQSLVDYHSIDLSQYDYILSTKPLTNQEIDVIS
                     SFPTVKELLELQERLQYVQAHRTIVARDAIAPEKSYDLQDYLISSSQLLSQFELVQLE
                     NNQSFEHTVEQIIQYQKNVSDRDYLTRKLLSHFQNSPMAIPNTGLVLLHSQSSKVTTN
                     SFTMFELKLPISALSMKREEEEVKRCLLMLMSKEASEEARDLMTAISQSIIENHLYTE
                     IYKTGNQSIIYQMLNTIFNEKIKKLEN"
     gene            complement(32340..34109)
                     /locus_tag="VW348_001287"
     CDS             complement(32340..34109)
                     /locus_tag="VW348_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HEU9746183.1"
                     /translation="MEEKVSLKVRVQKLGTSLSNMVMPNIGAFIAWGVLTALFIADGY
                     LPNEQLATVVGPMLTYLLPILIGYTGGYMIHGQRGAVVGAIATVGAITGSSVPMFIGA
                     MVMGPLGGWTIKKFDEKFQEKIRPGFEMLVNNFSAGLVGFALLLLAFYAIGPVVSTLT
                     GAVGNGVEAIVNARLLPIANIIIEPAKVLFLNNALNHGIFTPLGVEQVAQAGKSILFL
                     LEANPGPGLGILLAYAVFGKGSAKSSSWGAMVIHFFGGIHEIYFPYVMMKPTLFLAAM
                     AGGISGTFTFQLLDAGLKSPASPGSIIAIMATAPKGVWPHLNVLLGVLVAAVVSFFVA
                     ALILHADKSTEDSLEAAQEATQAAKAQSKGQLVSTSVDAVISTDSVEKIIFACDAGMG
                     SSAMGASILRDKVKKAGLEIPVSNQAISNLLDTPKTLIVTQEELTPRAKDKSPSAIHV
                     SVDNFLASPRYDEIVASLTGAFPIAEIEGDIPTSAPVDSQEIDLNHIDAVVVAYGKAQ
                     GTATMGCETIRAIFRNKNIRIPVSTAKISELGEFNSKNIMIVTTISLQAEVQQAAPNS
                     QFLIVDSLVTTPEYDKMAARMYK"
BASE COUNT        10151 a         7693 c         6468 g         9948 t
ORIGIN      
        1 ttctttacca ggggagtctc agcaaccatc atttttgagc actgatagca cttaaagcga
       61 cgctttctaa ggaggattct agtaggcata ccagtcgttt caagataagg aatcttagac
      121 ggtttttgaa agtcatattt cttcatttga cttccgcact cagggcaaga tggggcgtcg
      181 tagtccagtt tggcgatgat ttctttgtgt gtatccttat tgatgatatc tagaatcttg
      241 atgtttgggt ctttaatgtc tagtaatttt gtgataaaat gtaattgttc catatgaatc
      301 tttctaatga gttgttttgt cgcttttcat tataggtcat atgggacttt ttttctacac
      361 aaaaataggc tccataatat ctatagggga tttacccact acaaatatta tagagccaac
      421 aataaaaaga aaaagtgttt gatagatatc aaacactttt ttctttgcct cccactatct
      481 aaaaaaatga taatagatat aattgtaaac aaaaatccag ataggttttg catgattgag
      541 aaagttaaaa aaactatggc agagaatcgt taatctcaga ttgtcggtag aacgataaac
      601 aagggcaaaa aagaaaccaa tcagactata atataataaa ctaattggat ctctgtgaga
      661 tagtatcaaa tggctaatcc caaagatgat agcagatagg ataacatcca aatagtactt
      721 ggactaggga aagaaggtat tcataaaata ccctctatca agagtctcct caaaaacagg
      781 accgatgatt acaggcagga caaaagataa gatagtcgat aaaaaggttg gttgtccatt
      841 tgaaaaaagc acggtaaaat actcatcatg aatattccta tgattaatca aatgagcata
      901 gcgtgcccaa aaattaccga gaatctgata aaccacataa gttgcaaata agtagaagac
      961 aaatgaccag ttccagctct ttttctcaaa gataaagagc atctttttct tttttaacct
     1021 ccaaattaat agaaggaaac ttcccactaa tcccattgtt aaaataagag aatagacatc
     1081 agctcctaac cctaaaatga tcgtcacata caatccaatt gtttgtggta aataggtaga
     1141 tagtaaaata ataagcaaaa atattccaaa ttgtcttagt ttttttgtgt ttctcatcgt
     1201 acttttttga aagattaccc tgctcggaag ccgtacttcc aagcatctat ataagaatta
     1261 agtgcccctt gcctcatata gggagcaaat tctctataat ataaccatct actatatcca
     1321 tcttcccaaa cagcaagacc acctgaagtt tgctccaagt cctcagttga aagaactgta
     1381 aatgtatttg tacctgtcat tgcaagtacc ttcttaaaat agattgttgt aggctcacat
     1441 ttatagtata tttctttttt tgtctatttt atagcccatc tcctcaactg gcaatttttc
     1501 gacctgaatt acatttttcc ataaaaaatg agacctttct agtctcattt agtcattctt
     1561 agtattttct aaatcgttga tagcgttctt ccagcaactc ttctagcggt ttttgtgaaa
     1621 gtctagccag ctccgtttgg agttcttttt tgacactctt aatcagttct ttactagaaa
     1681 gtcctatttc agaaatcacc ttatccacca cgtccatttc taacagttca tgcgaagtga
     1741 ttttcatcag ttctgctgct tccatggcgc gagtaccgtc cttccataaa atggaagcaa
     1801 agccttctgg actgagaatg gcatagatag aattttccag catccagaca cggtccgcga
     1861 cagctagagc cagagccccg cctgaaccac cttcaccgat aataatggcg ataataggaa
     1921 ctttcaggtc actcatttcc atgagattgc gagcgatagc ttccccttga ccacgttctt
     1981 ccgctccgac accaggataa gcacctgctg tattgataaa ggtcacaact ggacggccaa
     2041 atttctcagc atgtttcatc aaccgcagtg cctttcggta gccttctgga tgtggttggc
     2101 caaaattccg tttgaggttg tcttgcaaac tcttgccttt ttggatacca accactgtta
     2161 cagcttgatc tccaagccaa ccaataccac caacaactgc accatcatca cgaaaagaac
     2221 ggtcaccatg taattggata aattcatcaa aaatgcctgt cgcaaagtcc aaggttgtca
     2281 agcgactctg ctcacgcgct tctctgacta tttttgcaat attcatctag gactccctcc
     2341 atgcaatctg actaggctag caatcgtatc tggtaagtct cttcttttga caatagcatc
     2401 cacaaagcca tgttctaata ggaattctgc cttttggaaa tcctcaggca agctttcacg
     2461 aaccgtattt tcaatcacac gacgcccagc aaaaccaacc aagctctgtg gttcagccag
     2521 aatgatatcg ccttccatag cgaaagaagc tgtcacacca ccagtcgttg gatctgtcaa
     2581 aatggtcagg taaaagagac cagcatttga atgacgttta accgccgcag agatcttagc
     2641 catctgcatg agactcatga ttccttcctg catacgggct ccaccagagg ctgtgaatag
     2701 gacaactggc aatttttcga cagtcgcata ctcaaacaaa cgagtgattt tttcacctac
     2761 aaccgtaccc atagaagcca tgataaagtt agaatccata atcccgagag ccacagtctg
     2821 acctttaata agagcagttc ctgtcacaac ggcttcatgc agacctgttt tttcacgcat
     2881 agatgccagt ttcttttggt aaccagggaa atgcaaggga tccttgcttt caatccctgt
     2941 aaacaattct ttgaaggttc ccatatcaat cgtcaaagcc aagcgttctt gggcagaaat
     3001 acgaaaggta tagctacagt gcggacagat acgttcactt cccagatcct tctgatagat
     3061 ggtatgctta cagcctggac actgggaaaa taattcatct ggaacctctg gcttagcttg
     3121 aggtttttcc ctaaccgaac gattgggatt gattcgaata tacttatctt ttttactaaa
     3181 tagagccatt gattcccctt ttcggtttaa actcttaaag tcattttatt ctttttcttg
     3241 atatttaggt aagaaggttt ccatcaagaa ggaagtatca taatccccag caatgacatt
     3301 gcgatctgaa atgaggtcaa gctggaaatc tgcattggtc tgcactcctt caatctctaa
     3361 ttcatagagg gcacgttgca ttttcatcaa ggcgtcaaaa cgattttcgc cgtgtactat
     3421 gattttggca atcatactat cataataagg cggaatggta taacctggat aaactgctga
     3481 atccacgcgc aagccaactc caccacttgg cagatagaga ttagtaatct tacctggact
     3541 tggagcaaag ttaaaggctg ggttttctgc attgatacga cactcgatgg catgaccgcg
     3601 taggacaata tcttcttgct taacagacaa aggctgacct gccgcaatgc aaatctgttc
     3661 cttaacgata tcaacacctg aaacaaactc tgttactgga tgttctacct gaacacgagt
     3721 attcatctcc atgaaataga aattgctact tgcttcatca agaagaaatt caatggttcc
     3781 tgcattctca tagccaacaa actctgccgc tcgaacagca gcagcaccta tttcatgacg
     3841 cagcgttttt ccgattgcaa tcgagggact ttcttccaaa accttttggt tattcctttg
     3901 aagagaacaa tcccgctcac ccaagtgaat cacatgtcca tgctcatcac ctaggatttg
     3961 aacctcaatg tgccgagctg gatagataac ccgttctatg tacatggcac cattgccata
     4021 attggccttg gcctcactag aggcagtttc aaaggcagaa acgaggtcat ctggtttttc
     4081 aaccttacga atccctttac cacctccacc tgctgaagcc ttgagcataa caggatagcc
     4141 aattttttca gcaacaatca aagcttcttc agagttatgc acttctccat ctgaacctgg
     4201 tataacaggc acacctgctt taatcatctg agcacgcgca ttgatcttat cccccatcat
     4261 atccataaca tgaccagatg gaccgataaa cttgatacct acttcttcac acatggtcgc
     4321 aaatttggaa ttttcactga gaaatccaaa accagggtga atagcttctg cctcagtcaa
     4381 gactgcagct gatagaactg cattaatatt gagataagac tctgttgcct tgccaggacc
     4441 aatacaaact gcttcatctg ccaaaagcgt atgaagagct tccttatcag cagttgaata
     4501 aaccgctacc gtcgcaatcc ccaattcacg tgccgcacgg ataatacgaa ccgcaatttc
     4561 accacgattg gcaattaaaa tttttcgaaa catggagaac ctccttagtt cccaattgca
     4621 aaagtaagga taccactggc tgcaagcttg ccatccactt cagcctttgc ttcaaccaca
     4681 gctatggtgc cacgacgttt tacaaaagtc gctgtcataa ccaattggtc gcctggtaca
     4741 acttgcttct tgaacttaac cttgtccata ccagcgtaaa agaccagttt tcctttattt
     4801 tcaggttttg ataactccaa cacaccagca gtttgcgcca aggcttccat aatcagaaca
     4861 cctggcataa ctgggtattg aggaaagtgg ccgttaaaga aaggttcgtt aatggtcaca
     4921 tttttgatag caacaatggt atcctcgctc acttccaaga cacggtccac tagaagcata
     4981 ggataacggt ggggaagagc ttctttgatt tcttgaatat cgatcatttg atacgtacca
     5041 atcctttacc aaactcaacc atttcttcgt tagagacgag aatttccgtt accacaccat
     5101 ccttaggagc tgggatttca ttcatgactt tcatggcttc gataattacc aatgtttgac
     5161 cttttttgac actatcacca actgtaacga aggcaggttt atctggtcca gcagccaagt
     5221 aaaccactcc aacaagtgga ctctctacaa gatttccctc agtagccaca cttgcttcag
     5281 ctggagctgg aacttcttct gctacagtct ctgctggagc agatgtagga gctactggac
     5341 tcggtgttgc tagaacgggt gctggagcga cttgagttgc aacttcaggc acaggtctcg
     5401 cttcattctt gctaaactgc aactcatccg tcccattttt ataagaaaat tctctcaaac
     5461 ttgactggtc aaattgagtc atcaagtctt taatatcgtt taaattcata cttatctatt
     5521 ctcccaacgt ttgaaagcaa gaactgcatt gtggcctcca aaaccaaaag tatttgaaat
     5581 agcgtatgga atttctttct ccaagccttg tccataaacg acattagctt cgatataatc
     5641 tgatacttca cttgtcccag ctgtcattgg tacaaagtta tggcgcatag cttcgatggt
     5701 gacgatagct tctactgcac ccgcagcccc cagcaaatgt cctgtaaaag acttggttga
     5761 tgatacaggt acttccttac caagaacagc tacgatagct ccactttctc ctttttcatt
     5821 ggcaggagtt gacgttccgt gagcattgac ataggctact tgctctggag aaatctcagc
     5881 ttcttccaag gctagtttga tggccttgat agctccctga ccttctggat gtggagaagt
     5941 catgtggtag gcatcacaag tatttccgta accaaccact tcagccagga tagtagctcc
     6001 acgtttttca gcgtgttcaa gactttctaa aaccaacatc cctgaacctt cacccataac
     6061 aaacccattg cgatccttat caaatgggat cgaagcacga gttggatcct ctgtagtaga
     6121 gagagctgtt aaggcttgga aaccagcgat ggcaaaaggt gtgatagaag cttctgttcc
     6181 tcccaccaac atcacatctt ggaaaccaaa cttaatggag cggaaggcat ccccaatcgc
     6241 atcatttgat gaagagcagg cagtattgat agatttacaa acaccgtttg caccaaaacg
     6301 catggctaca ttcccagaag ccatatttgg taaagctttt ggaagagtca ttggtttgac
     6361 acgtttgggt cctttttcat gaaggcgaag tacctgatct tcaatttcct tgattccacc
     6421 aataccagat gcaacgataa caccaaaacg atccctatta agagcctcta catcaagatt
     6481 ggcatgattt acagcctctt gggctgcata caaggcatat aaagaatagt tatcaaaacg
     6541 gttggtatct ttttttacaa agtatttatc gaacggaaaa tcttggattt ctgccgcatt
     6601 atgcacatca aagtcactat gatcaaattt tgtaatgcca ccaatgccga ttttcccagt
     6661 tgctaaacta ttccaaaatt cttctggtgt atttccgatt ggagatgtta ctccataacc
     6721 tgttaccact actcgattta gtttcattct tttcacctct agctttcgct acatacttaa
     6781 gccaccatca atggcaatca cttgaccagt tagataatct tggcctgcta aaaatactgt
     6841 caaatctgca acctgctctg cctgcccaaa ttctttcatc ggaatctgag ctagtgtagc
     6901 ttccttaatc ttatctgata agatagctgt catatcagac tcaatcattc ctggagcaat
     6961 cacattgact cgtatattcc gactagcgac ctcgcgtgcc acagacttgg taaagccaat
     7021 caagccagcc ttagaagcag catagttagc ttgaccaata ttccccatca aaccaacaac
     7081 actagacata ttaatgatag caccttctct ggctttcatc atcggtttca agactgattg
     7141 tgtcatatta aaggcaccag tcagattgac cttgagcact ttttcaaaat ctgcttctgt
     7201 catcttgagc ataagagtat cttgggtaat ccctgcattg ttgaccaaaa catctactga
     7261 acccagttct gcaatagctt gatcaatcat acgcttagcg tctgcaaaat ctgatacatc
     7321 tcctgaaatg ggaaccacct tgataccata gtttgaaaac tcagcgagca attcttctga
     7381 gattgcccca cgactgttta agacaatgtt ggctcctgct tgagcaaact tgtgggcgat
     7441 ggcaagacca attccacgac tcgaacctgt aataaagata tttttatgtt ctagtttcat
     7501 ttttttcctt tcaaaacttc tacttatttt agtctatttt tctaaaagtg ctactaaact
     7561 cgcttgatct tccacatgag ctaagtgagc agtttgatca atttttttaa caaaacctga
     7621 caagactttc cccggtccaa tctcgataaa gttgcttatg cctgcttctt gcatgacccc
     7681 aatactttca tagaaacgaa cgggttcctt gacctgacgc gtcaagagct gagcaatgtc
     7741 ctctttttgc atcacagcag cttctgtatt gccgactagg ggacaagtaa aatctgaaaa
     7801 acttacctga gctagagttt cagctagttt ctggctagct ggctcaagga gagcggtgtg
     7861 aaagggacct gacaccttaa gaggaatcaa gcgtttggca cctgcttctt gcaaaagttc
     7921 aaccgctcga tcaactgcaa ccacttctcc agcaatgacg atttgtgcag gtgtgttata
     7981 gttggctgga gtaaccactc caagttcaga agctttttga caggcttctt caatgacctc
     8041 tactggcgta ttgagaactg ctaccatctt gccagagtca gcaggagccg cttcttccat
     8101 ataggctcca cgcttagcta ccaaggcaac cgcatcttca aaatccaagg cgccgcttgc
     8161 caccaaggca gagtattctc caagagacaa accagcaacc atatcaggct gatagccctt
     8221 ttcttgcaat aaacggtaga tagcaaccga agtcgctaga atggctggtt gcgtatagcg
     8281 ggtctgattg agtttgtctt cttccgtatc gatgagataa cgcaaatcat aacctagcac
     8341 ctgactcgct cgatcaatcg tttctttaac aatcggatac tgatcataga aatcccgtcc
     8401 catccctaga tactgggcac cttgaccagc aaataaaaag gctgttttag tcatttctta
     8461 caactcctgt ccagcgagag gcttcttctt gaattttctt agcggctccg taatacaaat
     8521 cttttaggat ttcttcagct gtttcttctt tagaaacaag ccctgcgatt tgacctgcca
     8581 tgacagagcc accctccaca tcaccgtgaa caactgcttt ggctagggca ccggctccca
     8641 tttgttcaaa gatttctaaa tcaggatctt cctgcttaaa ggcatctttt tcagccagtt
     8701 caaaatctct agtcaactga tttttaatag cacgaacagc atgaccaaag tgctgagctg
     8761 aaatcgtagt gtcaatatcc cttgctttta aaattttctc cttgtagttt ggatgggcat
     8821 tcgactcttt tgcaactaca aaccgtgtcc ccacctgtac agcctctgca cctagcataa
     8881 agccagccgc agcaccttca ccatccgcaa ttcctcctgc agcaataaca ggaatagata
     8941 cagctgtggc tacctgtcgc accaaggtca tggttgttaa tttaccgata tgccccccag
     9001 cttccattcc ttctgcaata acagcgtctg caccgatttt ttccatgcgt ttagctaaag
     9061 cgacactagg aacgacagga ataacgatta tcccagcttc atggaaacgt tccatatact
     9121 tgcttggatt tcctgctcct gttgtgacaa ctttaacacc ttcttcaata acgagatcca
     9181 cgatatcttc cacaaaggga gataagagca tgatgttgac cccaaagggt ttatcagtca
     9241 atgatttgat tttatcaata ttggccttga caacttcttt cggggcattt cccccaccga
     9301 taattcctaa tcctccagcc ttggaaacag cccctgccaa atcaccatca gcaacccagg
     9361 ccatccctcc ttggaaaata ggatagtcaa tcttcaataa ttctgtaata cgcgttttca
     9421 tagtgcctcc aaccttcctt gcttacgtaa tagttcgatt tcaccataat ttgacagtca
     9481 aactattacc taaacaagag ggagtgggtt tctccctact ccttctacta atattctgct
     9541 tattttgctt gctcttcaac gtaagcaacc aagtcaccaa ctgttttcaa gtcattttct
     9601 gcttcgattt ggatatcaaa agcatcttcg atttctgaga ttacttggaa caagtccaat
     9661 gaatctgcgt ccaaatcatc aaaagttgat tcaagtgtta cttctgatgc gtcttttcca
     9721 agttcttcaa cgataatttc ttgtactttt tcaaatactg ccatgatagg actcctttaa
     9781 aataaatagt ttttttataa caatgtgttc accacatgat tacctaaatt gtaagaatga
     9841 gcgtgcccca ggtcaagcct ccaccgaagc ctgatagaag aacagtctgg ctaccatcta
     9901 aagggatgag accttgttct acacactctg aaagtaaaat cgggatactg gctgcactgg
     9961 tattgccata ttccatcata ttggctggaa gtttggctcg gtcaacacca atttttctag
    10021 ccatcttatc caaaatacgg tcattggctt gatgaagtag cagataatcc aagtctgtca
    10081 cctctatagg agattcatca atagtctgct tgatagactt ggctacatct cgaatggcaa
    10141 aatcaaagac tgtgcgtcca tccatcttca aaaatgaatc tgcactttct tgatctgaaa
    10201 atggagaatg caaacctgaa tgcccataag ttaaacactc gctgcgactt ccatcgctat
    10261 tgagactctc agctaagaaa tgctcttgct cgctagcttc taacaagaca ccaccagcac
    10321 catctccaaa caacacagct gttgatcgat ccgaccaatc gactgcctta gagagggttt
    10381 cactaccaat caccaagcct ttttgaaagc gaccagaagc gataaacttt tcagcagttg
    10441 aaagagcaaa tacaaatcca ctgcaagccg cggttaagtc aaaagcaaag gctttattag
    10501 caccaatatt agcttgaaca cgagcagctg tagagggcat catcgaatct ggagtaatgg
    10561 tagctaggat gataaaatcc agttcttctc ctgttattcc agcttttgcc atcagtttct
    10621 tagcaacctc tgtagccaaa tcactggtag attctgttct tgaaatatgc ctttgtcgta
    10681 ttcccgttcg acttgaaatc cactcatcat tggtatccat aatctgagcc aagtcgtgat
    10741 ttgtaaccac ttgctctggc acataatgag caacctgact tatttttgca aaagccatta
    10801 tttcaaatcc tccaaaaatt ggtaaagatt agtcaagcct ttacccatga cagcaatttc
    10861 ttcctcgctc atgccatcaa taattttttc taccatggcc ttgtggaagc gtttatgcag
    10921 tctatgaatc aagcgaccct tctttgtcaa atgcagatgc accacacgac gatcctgttc
    10981 tgaccgaact cgctcaatgt agcccttacg ctctaaattg ttcaaacttg tcgtaacagt
    11041 tccaagagtt accatcaact cttttgacac ttgacttgga gtcacatctg gagccttacc
    11101 gatgacatca atcgtatgca tttctttgat ggagatatcc ttaaaacgac tacctctcaa
    11161 gttcacttcc tcaattacaa ggacattgtt aaatatagat gttaaatatt cattgattcg
    11221 ttggtagtcc atttttcata tccctccttc ttcaaaaaac ttttacaatc aaaacatttg
    11281 acagaaagaa ttatatcaaa attcaaagaa tgatgcaagt attttttatt ttcctgtaaa
    11341 tttaggtctt cttctctccg aatgagctcg cactccttct ttgaaatcct ctgtttgagc
    11401 taaggatttc tgtaggttca gttctaaagt agcgtaaccc tgccagtctt taaattggct
    11461 ctcccaaacc aacttcttaa tggcagcata ggaattactt gaagcacgtc ttaatttttt
    11521 aagaagctgt tctctcgtct tttcaagttt ttcagcttca gaaacgcggt aaaccaaccc
    11581 ccattctagg gctttttctg ccgttaaagc ctctcctgtc atagctaatt gagcagcacg
    11641 cgtcacaccg atactgcggc tcaagagatg aattccccct gcatctggag ccaaaccaac
    11701 accaacaaag gcttggataa acttagcctt atccgtcgcc aaacagaaat ctgccgcaac
    11761 agccatattc gctgcggcac ctgcaacagc accgtcaact tccattaaaa caggtttggc
    11821 tatttgcttg attttataag aaatcgtatt gaccaactct gcgatttttg tcaatgatgg
    11881 aatatcatcc tcatccactg cccgcttcat ctctaccaaa tctcccccaa ctgagaagac
    11941 cttcccattg gcattgatta agataaaatg cacagctgga ttttcttctg ccaaagtcag
    12001 agcttctaaa atctcctcac acatgggaat atgaaaacca tttgcgacct caggacggtt
    12061 caaggtaagg attgccaagt cctcttcaag ctgataaata atgtgttcca tcagggctcc
    12121 tttttatttt ataagcagtt tatactcttc gaaaatctct tcaaaccgcg tcagcttcca
    12181 tctgcaacct caaaacagta ttttgagctg acttcgtcag tcttatttac aacctcaaag
    12241 cagtgctttg agcagtctgc ggctagcttc ctagtttgct ctttgatttc attgagtgtt
    12301 aaattatttc actgtcaaag tatatctttt ttaggagcag aaagcaagaa aaaatcgact
    12361 gaaagtgtct cagccgataa gaaaggctcg ctttaggcta gaaagcatct tattttcttc
    12421 attgaaaaaa gcctttcttt ctgctataat cgtataaaat acttacttta ggagttctta
    12481 tgaaagttgt taaatttgga ggtagttctc ttgcctctgc tagtcaatta gaaaaagttt
    12541 taaacatcgt caaaagcgat tcagagcgtc gttttgtagt cgtttctgcg cctggtaaac
    12601 gcaatgctga agatactaag gttacggatg ccctgattaa atactaccgc gactatgttg
    12661 cgggtaacga tattagcaag agccaaagct ggattatcga ccgctatgct gctatggtta
    12721 gtgaattggg actaaaacca gctgtgctag aaaaaatttc taaaagtatt cacgccttgg
    12781 ccactcttcc tattgaagaa aatgaatttc tctacgatac tttcctagca gccggtgaaa
    12841 ataacaatgc caaattgatt gctgcctact ttaaccaaaa tggtatcgat gcacgctata
    12901 tgcaccctag agaagctggg attgtggtca caagtgaacc tggtcacgct cgcatcattc
    12961 catcaagtta tgacaagatt gaagaattga caaacaccaa tgaagtcctt gtcattcctg
    13021 gtttctttgg tgtcactaag gaaaatcaaa tctgtacttt ctcacgtgga ggttctgata
    13081 ttacaggttc tatcattgct gctggtgtca aagctgacct ctatgaaaac tttacggacg
    13141 ttgatggtat ctttgcagcc caccctggta ttatccacca accacactcg attcctgagt
    13201 tgacctaccg tgaaatgcgc gagttggcct atgcaggctt ctcagtcctt catgacgagg
    13261 ctcttcttcc tgcctaccgt ggaaaaattc ctctggttat caagaatacc aacaaccctg
    13321 accatccagg tactcgtatc gttctaaaac acagtaatga tgaatttcca gttgtgggaa
    13381 ttgctggtga ctcaggcttt gtcagcatta acatgtcgaa atacctcatg aaccgtgagg
    13441 ttggatttgg ccgcaaggtt ctgcaaatcc tggaagaact taacatcggt tgggaacata
    13501 tgccaacagg tatcgacgat ctttctatca ttctccgttc tcgccaacta actcccatca
    13561 aggaagaaga aatcctgcgt cagttggttc aaaaggctaa agtagatcat gcagaaatcg
    13621 aacacgacct ttctatcatt atgattgttg gtgaaaaaat gaagagccac atcggagtga
    13681 ctgctactgc gacacgcgct ctatctgaaa acaaaatcaa catccagatg atgtctcaag
    13741 gttctagtga agtttctatt atgtttgttg tcaataaaga ccaagagaaa gcagcaatta
    13801 aagccctcta caatgccttt tttggagaaa gtaaggaaga ctaagcatgg cccaatcact
    13861 taacaaaaca gtactcctca gtacgacagg cacttcctac ctctctatcg ctgggaaagt
    13921 tgggaaattc cttgtcggag atcaggcttt ggaattttac ccagatgtca atgtcgaaca
    13981 atttatccag attccttgga gccatatcaa tcagattgga gccaatgtca ctggacgcaa
    14041 aatcagccgc cacttcgaag tctttacaga caaaggaaaa ttcctctttg cttcaaaaga
    14101 ctcaggtgcc attctcaaaa ttgcacgcga aaaactaggc aatgacaagg tcgtcaaact
    14161 tccgaccctg attcagacaa ttagccaaaa atttaaaaat ctatttgcaa aaaagtagaa
    14221 actttagtat aatcatagca acggataagt aggttatctt cttctttcag aaagtctgcg
    14281 ggtactgcga gcagatagga gggataggtg aaattctacc gttagtaaca attacataca
    14341 caatcaagtg cacacctgtg aagttggatg gaaccgtggc cctgccactc caacgttttg
    14401 tcaggcgtgc ttttttcata aaggagttct tatgttagat atcaaacgta ttcgtacaga
    14461 ttttgaagct gtcgcagaaa aattagctac acgtggtgta gatgctgctg tcttgaatga
    14521 aatgaaagaa atcgatgcta aacgtcgtaa catcttgatt aaggttgaaa ctctcaaagc
    14581 agaacgtaac acagtttctg ctgagattgc ccaagctaag cgcaacaagg aaaatacaga
    14641 tgacaagatt gctgccatgc aaaatctatc tgctgaggtt aaagccttgg atgctgaatt
    14701 ggcagaaatc gatgctaaat tgacagaatt tacaacgact cttccaaata tcccagctga
    14761 cagcgttcct gttggggctg acgaagacga caatgtggaa gttcgccgtt ggggtactcc
    14821 acgcgagttt gacttcgaac ctaaagctca ctgggatctc ggtgaagacc ttggtatcct
    14881 tgactgggaa cgcggtggta aggtaacagg cgctcgcttc ctcttctata aaggcctcgg
    14941 tgctcgtttg gaacgtgcta tctacaactt tatgttggat gaacatggaa aagaaggcta
    15001 tactgaagtc atcacacctt acatagtcaa ccatgattct atgtttggta ctggtcagta
    15061 tccaaaattt aaggaagata cttttgaact cagcgatacc aactttgtct tgattccaac
    15121 tgctgaagtt cctctgacaa actactaccg tgatgaaatc ttagacggca aagatcttcc
    15181 aatctacttc actgccatga gtccgtcatt ccgttctgag gctggttctg ccggtcgtga
    15241 tacgcgtggc ttgatccgtt tgcaccaatt ccacaaggtt gaaatggtca aatttgccaa
    15301 accagaagaa tcttacgaag aattggaaaa aatgacagcc aacgctgaaa acattcttca
    15361 aaaactcaac cttccatacc gtgtcgttgc tctctctact ggagatatgg gcttctcagc
    15421 tgcgaagact tacgacttgg aagtgtggat tccagcacaa aacaattacc gtgaaatctc
    15481 aagctgttca aacacagaag atttccaagc ccgtcgtgcc caaatccgtt accgtgatga
    15541 agcagatggc aaggtgaaac tccttcatac cttgaacggt tctggacttg cagttggacg
    15601 tacagtggct gcaattcttg aaaattacca aaatgaagat gcttctgtga ccatcccaga
    15661 agcacttcgt ccatacatgg gtggagctga agtcatcaaa ccataaaaaa taaggtttag
    15721 ctatttctag ctagaccttt tttcgtaacc aaatcagata agcacctagt acaaagaata
    15781 aaatagttag gcatataatg gtttcagcca ataccaggta atccagaaat ggaagtttca
    15841 aaattccctg agccatcttg agcgaggtcg ctgtgataat ggttgggaag gtgagggctg
    15901 agaaggctgg ttgaaaacct tgttttaaaa tgttgggcag acgagttaaa acaaagaaaa
    15961 agaaggattg agaagccaaa atcatgacaa tcaagaccca agtcggcagg ctggttcctc
    16021 ctactcgaac tagagaagcc aagagtagag agaaaggagc acagtagatt ccttcttgtc
    16081 caagcaaggc tagtgggagt ggatgtttct ttaaatcgct ataaataagg ggatagagat
    16141 agaaggtcaa gagaaaacca aaactcaagg tcgcataggc aatttcgata atacctacca
    16201 gaggataggt caaggcagcc actgctatcc ccacatagag aaccgtccaa cttggagtgg
    16261 catgaaccct ccgccctgga caagcaaact tgatggtaaa accagcaatc aaggtcaaat
    16321 ccaagagaaa tgaaaaccac caaatccctt gtgctaccaa aggaagataa gagaatacgc
    16381 gaaagacata ggtcgataaa atcatcccag ccataggaaa ggttgccatt cctgacaaaa
    16441 gagggggctt ggtcaattct tgcttggttt ctttccaatt aaagagatgc agaattagaa
    16501 agtaaatcca taaaaccaaa ccagtcagac taaaaagatg ggatagaacc ggcaacgtat
    16561 ctaaaataag atttccagct cctgccaaac ctagcaaaca acctgaaaat actaagggga
    16621 gttttttcat cctaacctcc aataatcatg ttagtttcag tataacataa aagcgcttaa
    16681 atgaggattt aaaaaaacga agtccgctta tttcagactt cattttactc agatatgaat
    16741 taggcataag gttgcaattc tggattaatt ggtgtattag ctaagttgtt ggcatagtta
    16801 cagaggattg ctaggctgac accaaaaacc acatccaagg cattttgttg agtgtagcca
    16861 gcttctaaaa actcagacaa ggcttcatct cctacacgac ccttggtatt gataactgcc
    16921 aaggtaaact tagctagggt atccaattta ggatctgttt caattggagt acgattgcga
    16981 agagcttgaa tcaagtcatc attcatctgg atttgtttga tggaaaaggc tgtgtgacct
    17041 gcgacacaga aggcacaacc attggtcacg gctgccgtga tttgcaccac ttcacgctca
    17101 acgggtgtca ggctgttgcg acggtggata gatgagacaa tttgataggc ttctaaaaca
    17161 gtcggggcat tggccaagag accgattagg ttgggaatat agccattgtt gtctttttct
    17221 actgtttcaa gaatttcttt cacttctgct ggtgctgact ctactgtatg gatagtaaat
    17281 gttgtcataa gatacctctt ttcttattat tgacactaat attattggaa aatcttataa
    17341 aatcctgatt cctaagttta tctaagataa agctttattc tctcataaga ttttcgttgt
    17401 tatattagtt tatcacactt ccaatcactt gcataatata tattatatat caggctgata
    17461 aaaattattt ataggcaaaa aaatcacacg agctgtgtga ttccattatt tgtcaaaata
    17521 ctttttagtt tcagcaataa cgactggcga caagaccaag agggcaatca agtttggcag
    17581 agccatcaag gcgttaacga tatctgcgat aatccagacc atatccaact cgataaatcc
    17641 tcctaacaag accatgagca caaaaaccac acggtagagc cagataaagc gaaccccaaa
    17701 gaggaactca aaacagcgtt ctccgtaata gttccaacct agaatcgttg taaaggcaaa
    17761 aagtacaagg aagatggtca agagggcagg cccaaagtgt gaaaagactg ttgagaaagc
    17821 tgactgagtc aaggcaaccc cattcaagtc accactccaa actccagtta ccaagatggt
    17881 caaaccagtt agagtacaaa tgatgagggt atcaataaag gttcctgtca tggaaatcaa
    17941 accttgctct actggttcat ttgtcttggc agctgcagct gcaataggag cagaacccag
    18001 accagattcg tttgagaaca caccacgcgc cacaccattt tgaatagcca tccgaacgct
    18061 agcaccagca aatccaccta ccgcagcaag gggactaaaa gctgaggtaa agactaaagc
    18121 gattgtgcca gggatttttc cgatattaaa gaaaataact gtaagagttc ctaagatata
    18181 aatgatggcc ataaaaggaa caacagtagt tgaaacctta gaaatagact tgagtccacc
    18241 aaagactgca atcgctacaa agacagacaa gacgagagct gtgatggctg gcgaaatcgt
    18301 cgttgtattt tggatagatt ctgcaatcga gttgacttgg gtgaaggttc cgattcccaa
    18361 gagagcaacc aatactcctg ctactgcaaa caaaacagca agtggtcgcc acttttctcc
    18421 catccctaga aggatataat gcatgggacc tcccgctact gcaccatggt cgtccttggt
    18481 gcggtatttg atggccaaga gtccttccgc atacttggta gccattccaa agaaagccgc
    18541 catccacatc caaaatagag ctcctggtcc accaaccttg atagccgtcg caactcctat
    18601 gatatttcct gttccaacag ttgatgccaa ggctgtacac agagctgcaa aactggatac
    18661 atcaccatgt cccttatcct ggataaaaat aagctgaaaa gccttgggca gacgcaaaac
    18721 ctgcaagagt cctagccgaa tagttaggta aatccctgtt ccgaccaata aaatcaagag
    18781 gggcggtccc caagcaaaag catcgattga tttaagcaat tctaacattt ccttctccta
    18841 tcgtttcaac cccaaaagaa agagcacatg caagatacat gtactctgga atgcttagat
    18901 aaatgctaaa aagcggtcta tcctagctct gtccttttac ctgagagttt gagcagttgc
    18961 ctgccttgcc ccttcggtgc ctttacggtc tctccagagt tccgtccatt tacagtcatg
    19021 gaaaatcaaa cgattcccca cttctattaa acttcattcg gtgttggtat ttaattgatt
    19081 ctaattttac aaaaaatgtt ggcttttgtc aatgtgttta ttagtaaaaa ttagttcaac
    19141 agtttttact ttataaagtc cagaatactg ctatccttta aaagtgacaa tagtcgcacc
    19201 actgcctcca gcattttgtg gggcatagcc gaaactcttg acatgtttgt ttctttgcaa
    19261 gtatttggta actccttcac ggatgactcc tgttccgata ccatggatga tatcaacttg
    19321 agccatattg ttaagcaagg cttggtcgat gaaggtatct agctcattca tggcttcttc
    19381 atagcgcttg cctcgaagat ccagtctagc ttgaggtcct cgcccagaag ttcgtttcac
    19441 aacattgacc tgtttcttct tgactggttt ttcttgctgg gcttgaacaa gatcaaactc
    19501 tttctcttcc aaggtcatct taatcaagcc aacttgggct tcccagcggc cgtccttgag
    19561 ttgactggtc aaggtaccac gctgaccata actgagaacc acgatatcat ctcccacctt
    19621 tggagctcgt tttttcttgg ccttttgaag gaccttgttt ttagacaagt ccactttttc
    19681 aggagccaat tttttcaact tggccttggc ttcaatgatt tcgtggggct tgagttggga
    19741 tttactgtgg agatttttga gaatctggtc actttcactt agggccatat ccacaatctc
    19801 agcagcctgt tcacgcgcct tgttaagctc ggtttccttt tcacgattaa gctcgttgta
    19861 gagttttttt agcgcacggt tcatcttgag attttcttgc tccacctcac ggatattgtc
    19921 caagcgtttg cggctttcca gcgtctgctc ttctaattgc tcaatgatac gattgacgtc
    19981 attgtcctga tcgatctgct gactggcatc tcctacgata acttcagata ggcctagacg
    20041 tttggcaatt tcaaaggcat tacttcggcc aggaacaccc tgcataaagc gataggtcgg
    20101 gcgaagagtt gcagtatcaa actccatact ggcattttgc acaaaggctg tctcaatacc
    20161 gtaggccttg agttctggat agtgggtcgt cgccatggtc ttgatttgac gcaggcgaag
    20221 gtcctccaga atagccatgg caagggctgc tccctcttgg ggatcagtac cagcccccaa
    20281 ctcatccaaa agtaagagtg aatgttggtt gaccttgcca agaatatcca cgatattggt
    20341 catatggcta gagaaggtag acaagctctg ctcaatagac tgctcatctc caatatcagc
    20401 aaaaatttct tcaaaaatac caacacgact tcccttgtct gctaaaatcg gcaatcctga
    20461 ctgggccatg acctgtgtca agcccagagt tttgagcatg atggtcttcc cacctgtatt
    20521 gggacctgta atgacaatag ctgttaaatc ttgaccaaaa tagacatcat ttgcgacggc
    20581 atttttgacc aaaggatggc agacatggag cagttgaatc tcttgatttt ctgacagctg
    20641 aggcacgact gcttgtcttt cttggataaa tcgaaccttg gcacgaatca agtccagatg
    20701 accgataatc caagcatcat tagcaatctc agccgcatga gggcggacac gctcagaaat
    20761 ttcttggaga atgcgaagca tttcatagcg ctcatctgct cgcagactag caatttcttc
    20821 gctcagtttg actacctcac ggggttcgat atagacggtg tttccactag cagaaatatc
    20881 atgaacgaca cctgcaatct tattgcggta ggtgtttttg actggtaaaa ccttacggcc
    20941 atttctgcta gcaacaattc cttccgtcaa catctgcgct ttttgcttga gcaagtcttg
    21001 taaaacatcg cgtacctgac tctcgctatc atgtattttt cgacggattc gcgccaattc
    21061 ttcactggca aaattttcaa tgaaacccgc atcattaaag gcctgaagat ttccttgtaa
    21121 ttgcggaaaa tcatgtaatt tctcaaacca aagggctaat tcttccaagc tgacattttc
    21181 cagattggcg taaaaacttt gaagttctcg gctggcaaga agcacgcgtt tcaagagtag
    21241 gaactcctcg atattgagat ccgctcccat ctccaacctc ttgcagactc ctgcaatttc
    21301 cttagttgag agaatagtaa aatgcggttg ctcgacgaaa agagcctgca tttccttcat
    21361 ctcagcaaaa gcctgtttga ttttatctgc tttggcagtc ggagccagtt gtctcaattg
    21421 ctccaagccc tgctcggtca acaaatgagg ctcaaacaag gccttgacct tatcgaactc
    21481 taatgtttct aatattttct tattcatctt tatttccttg tctttgaatg tctaggtgtg
    21541 gtaacttttt acattctgat agattcaagt caaatctgta aacaaagggc taggaaaact
    21601 cctgcccttt ttatccgatt aaatttgtca cccagatttg tttgagccaa ctggttgtta
    21661 tcggtatgct ctggatgatg tgttttgcga cgatactctt ttcaagagga ttttgtataa
    21721 ctgccatggg gatggtcgcc aagattgtca aggccatttg caagacaaat aaggtcacca
    21781 acatggacaa gatacctgct gaaacttgga acaacttacc acccagtttt ttgctaggaa
    21841 tcaagtgtaa gagaagacca agcaaacgac caatgctata gacaatccca aatacaagca
    21901 agtagccgat acctgcataa aagaccttat ccagctgaaa gagttgatcc gatgggaaaa
    21961 agaaagtccc ctgaccttcc tgcgaatttg cataagggag caataaatgg aattgctctc
    22021 caagcccctt ataaaactgg ccagccataa aagccgatgc catggctgaa atcaggtaat
    22081 aaatctgtaa gagcaggcct ctccgatagc cgatataaaa tccccaaacc aagaccaata
    22141 gaagaaggaa tgaaatcata aggaatcctc aatcttgctc tgttcttgct tacaagtcac
    22201 aagcttgtga cggagttctt ctagctcttg ctccttatcg tcaaattcaa tctcacggct
    22261 gagctgagtt gataaacagt tgactgccaa caaaagagcg attgtttcat catctgcgct
    22321 aggcatttgt tctttaattg cttggtattt ttctgtcgca accttagcga tttcctccat
    22381 aaaaaggtta tcatgttcac ttgtcaaggt taacgatttt ttcccgaatg taaatttgaa
    22441 tcgatttaga tttgccataa aattcacctc acgatattat accaaaattc gctaattttg
    22501 tcagttttta caaattttac tgcttttgtg gtacaataga aactatggca agtatcacac
    22561 tcacaccaag cgaaaaggat attcaggctt ttcttgaaca ctatcaaacc agtctggctc
    22621 ctagcaagaa tccctatatc cgctactttt tgaaactacc tcaagcaacg gtttctatct
    22681 atacttctgg aaaaatcttg cttcagggtg aaggggctga aaaatacgcc agtttctttg
    22741 gctatcaagc tgtagagcaa accagcggac aaaatcttcc tttgattggg acagatgagg
    22801 tagggaatgg ttcctacttt ggtgggcttg cagttgtggc ttcctttgtc acacctgacc
    22861 agcatgcctt cttacgaaaa ctcggtgtgg gagattctaa gactctgacc gaccaaaaga
    22921 ttcgtcagat tgctcctatt ctcaaggaaa aaattcagca ccaggcactc cttctctcac
    22981 ccagcaagta caacgaggtc atcggagacc gctacaatgc tgtttcggtt aaggttgccc
    23041 tccataatca ggctatctat ctcctccttc aaaaaggtgt tcagcctgag aaaattgtga
    23101 ttgatgcctt taccagtgct aaaaattatg acaagtactt ggcacaagag accaatcgtt
    23161 tcagcaatcc tatcagcaat cctatcagct tagaagaaaa ggctgagggc aaatacttgg
    23221 ctgtcgcagt ttcttctgtc attgcgcgtg atctctttct ggaaaatctt gaaaatttgg
    23281 gacgagaact gggttatcag cttccaagtg gagctggaac ggcttctgac aaggtggcta
    23341 gccagatttt gcaagcctat ggtatgcagg gactcaactt ctgcgccaaa ttgcacttta
    23401 aaaatactga aaaagcgaaa aacgcttaga aaggtaagtt atgaatttat ttaaaaattt
    23461 cttaaaagag tggggattat tcctcctgat tctgtcatta ctagctttga gccgtatctt
    23521 tttttggagc aatgttcgcg tagaaggaca ttccatggat ccgaccctag cggatggtga
    23581 aatcctcttt gttgttaagc acctccctat tgaccgtttt gatatcgtgg tggcccatga
    23641 ggaagatggc aataaggaca ttgtcaaacg tgtcatcgga atgcctggcg ataccatccg
    23701 ttacgaaaat gataaacttt acatcaatga caaagaaacg gacgagcctt atctagcaga
    23761 ctatatcaaa cgcttcaagg atgacaaact ccaaagcact tactcaggca agggctttga
    23821 aggaaataaa ggaactttct ttagaagtat cgctcaaaaa gcccaagcct tcacagttga
    23881 tgtcaactac aacaccaact ttagctttac tgttccagaa ggagaatacc ttctcctcgg
    23941 agatgaccgc ttggtttcga gcgacagccg ccacgtaggt accttcaaag caaaagatat
    24001 cacaggggaa gctaaattcc gcttctggcc aatcacccgt atcggaacat tttaagagac
    24061 ctaagaggcc gagaatcacc aatctcagcc tcttcttcta tcgtgagaaa atgattggta
    24121 actatctaaa cttaccagaa cagaaacacc tcaactctca cctattcatg caaaggaatt
    24181 ttatggaagt ttatttttca ggaaccattg aacggattat ttttgaaaat cccagcaatt
    24241 tttatcgcat cctcctccta gaaatcgacg atacggacgc agaggatttt gatgattttg
    24301 aaatcattgt cacaggaacc atggctgatg taattgaggg cgaagactat actttttggg
    24361 ggcaaattgt ccagcactcc aagtatggag aacaactgca aatcagtcgt tatgatcgcg
    24421 caaaaccaac tagtaagggc ttggtcaagt acttttcaag tagccatttc aaggggattg
    24481 gtctcaagac agctcagaaa atcgtggata cctatggcga aaataccatt gacgaaattt
    24541 tgcaacaccc agaaaagtta gaaggcatcg caggactctc tgccaaaaat cgcgaggctt
    24601 tcgtctccac tctccgtctc aactacggaa cggagatggt tttggccaaa ctagccaact
    24661 acggcattcc caacaaacta gcctttcaga ttcaagactt ttacaaggaa gaaacccttg
    24721 atgtggttga aaattatccc taccagctgg ttgaggatat caagggtttg ggctttacca
    24781 ttgctgacca actagctgag gaactaggca tcgaaagtca ggctcctgaa cgcttccgcg
    24841 ccggtctagt tcacagtctt tttcaggcct gtatggaaac aggggacacc tatgttgaag
    24901 cacgggattt gctggaacaa acccttactc tccttgagtc ttcccgtccc gtggaactag
    24961 accccagcca agttgcccaa gagctctcct acctgatcga agaagacaag gttcagcaga
    25021 ttgataccaa gatctttgac aacagcctct ttttcgctga ggaaggcatc cgcagtcact
    25081 tggttcgtat ccttgaaaaa ggaaaacaga agagtcatga tttaaaaacc attcaaaaac
    25141 atatcactac tatcgagaaa gagcttggaa ttgagtatga taacattcaa aaacaggcta
    25201 tctgtgatgc tatccagaat aaggtcttta tcctgacagg tggacctggt actggtaaga
    25261 caactgttat caatgggatc atcgctgttt acgccctgtt agagggactt gacctcagga
    25321 agaaaagcaa cctgcccatt cttcttgctg ctccaactgg tcgagctgct cgtcgcatga
    25381 atgaattgac aggtttgcct agcgcgacca tacaccgcca cttgggaatg acaggtgacg
    25441 atgataccag tcatctggaa gattacctag atgctgactt tatcatcgtg gatgaattct
    25501 ctatggtgga tacttggctg gccaatcaac tcttctccag tatctcttct aacagtaaga
    25561 tcctcatcgt aggtgacagt gatcagctac cttctgtcag tcctggacag gttctagcgg
    25621 atctgcttca tattcctttg attcctcaga ctcgcttgga aaaaatttat cgacaaagcg
    25681 aagaatcaac catcgtcacc ctagctagtc agattcgaca gggcatcttg ccagctgatt
    25741 tcacccaaaa aaaagctgac cgttcctact ttgaaattgc tagtggccat attcctgcca
    25801 ccattgaaaa aatcttaggt gccgccctca gaaatggtat tcctgcccgt gatatccaag
    25861 ttctggctcc tatgtaccga gggacggcag ggattgatgc tatcaatcag ctcatgcaag
    25921 acctgctcaa tcccccacaa aaagatcaac tcagttttga agctcctcag tgccactatc
    25981 gtaagggaga caaggtcatt catttggtta acgatgctga aatcaatgtc tttaatgggg
    26041 atttaggagc tatcacagac ctgattcctg gtaaatacac cgaatcgaaa caagacgaga
    26101 ttgtcattga ttttgatggt aatgaagtct cttacccccg taacgaatgg tacaagattc
    26161 gcttggccta tgccatgagt attcataagt ctcagggaag tgagttccca gttgtcatcc
    26221 taccgattac tagtgctagc cgacgtatgc tggagcgaaa tctcatctac acagccatta
    26281 cacgtgccaa aagcaaactc atcttactag gcgaattaca agccttcgac tatgctaccc
    26341 aacacatcgg aactgcccga aaaacctatc tgattgaacg cttcagtgat ctactggaga
    26401 atgttgaaga aaagcaacaa gctgtctctg aaacagtcac atcaagtgcc tctgaacaat
    26461 cctacatcct aaccgaagaa aactgggaca gcattccagc catgattggg attacagaca
    26521 cagacctcaa agagattttt ggaaaatagt acatcagaaa acccaccaat tcaggtgggt
    26581 tttctgttta ttaagattat tttactgttg ctgtgcttgt gatcaattca acagcttttt
    26641 tgatagtgat atcatgtttc aacatgtcag ctgaaagcaa gttttgaact tgtgcaactt
    26701 ccatgttgta gtctgctgcc aattgctcaa cttctttttg gatttcttct tctgaagcat
    26761 caaatccttc agctttggca actgcttcga taacaaggtt agtcttagta cgtgactcag
    26821 cttctgcttg gtattggttg tgaaggtctt cttgagtagt tccagtgatt tggaagtaca
    26881 tgtcagggtt gatcccttga cgttgcaagt tcccaaggaa ttcatttact gaacggtgaa
    26941 cttcttcatg gatcatttct tctggaagtt ctacgatttc agcgttttct acagctgtat
    27001 caattgctgc accttcaact gcatctttgt aagcttcttc tttagcagca gccaattctt
    27061 tgcggtattt ttctttcaag tcagcaagtg tttcaacttc ttcatcaatg tcttttgcaa
    27121 gttcatcgtc aagagctgga acttctttag cttttacttc gtggatagtt gtcacgaatt
    27181 tagcttcttt acctgcaagg tcttctgctt ggtagtcttc tgggaatgtt acgataacat
    27241 caacggtttc gccagctgag tgacctacca attggtcttc gaaaccaggg atgaattgac
    27301 ctgaaccaag tccaagtgag aagttttcac cttttccacc gtcaaattca acaccgtcga
    27361 tagaaccaac gaagtcgatc acaacagtgt cgccgttttc agcagcagct tccttgataa
    27421 ccaattcagc caggttgttg cgttcgcgtt cgatacgctc ttcaacatca gcgtcagtta
    27481 cttctttttc tacatcaact gatacttcaa ggtttttgta gtcacccaat tttacttcag
    27541 gttttgtaac gacttcagca gcgataaccc agtcttgacc tttttccatt gaagttacgt
    27601 caatttttgg ttgggcaacc acttcaagac cagcttcttt tacagctgct tcataagcgt
    27661 ttggcaaaag agcgttcata acgtcttggt aaagtgattc ttcaccaaat tttttatcga
    27721 agataggacg tggaaggtga cctttacgga aacctggaac attaagagat ttcttcactg
    27781 acttgaagac acggtccaat tctggtttga tttggtcttg agagatagtg aaagtcaaga
    27841 caccacggtt tgtttctttg ttttcaaatg atacagacat tctgtcattt ctccttaaaa
    27901 ttttttaaat acagtctatt ataacatttt ctataaataa aatctagact aatgcagcca
    27961 attatagaca acaagccttt ttcctaacta aaacactcat aaagtataga caattttaga
    28021 ctactttgga tatcttttgg ttagtcattt tccaaaacta atttatctaa tttttcagtt
    28081 atatagtaga ttgaaactag aatagtacac ctctacttct aaaacatttt tagaaatcgc
    28141 tttgactgtc ctgatcgatt tgtcctgttc ttgtttcatt ttactatata gatcgcattc
    28201 gaaagaattc gttccaaaat tgcttggttc gttcttctct tggacgacta aagaattgat
    28261 gggcattatt tttttcaaca attttcccac cgtccataaa aataacatga tgggctacat
    28321 ctctagcaaa acctatctca taaagctgat caaaaactca atctgaggag aaaatccaat
    28381 aaggctttcc ataataaagg acatcctatc aagatttttg aacacccgat aggctgcctt
    28441 tttccgattt tgaagacttt ttgtccagct tcttttacct tataaataac aacaaaaatc
    28501 aaagacaagc tagaaagatt accgcagata actcaaacag tgttttgagg ttgcagataa
    28561 gactgacgga gtcagctcaa agcactgctt tgaggttgca gataagactg acggagtcag
    28621 ctcaaagcac tgctttgagg ttgtagatag aactgacgaa gtcagtaaca tatgcctaag
    28681 acaaagcgat gctaacctga tttgaagaga ttttcgaaaa atattaaata tactctacaa
    28741 tttgctcaat caattcttgg tcgtctaaac ctgtaacttg tataacaaca tctttgactg
    28801 attgtttagc caacaattca cctaatcgaa tactttcttc atcatttaca tcgcgatagt
    28861 caaaggcata gccaactgtt ttaagtaggt ttttatatga caaactgagt tctttcaatt
    28921 cacgtatcgg ccggatgaat cgttcattat agcctaattt tcggattgga gtacgagcta
    28981 cgcgactaac ctcgtccact atgaaagggt tttcaaaccg ttctataatg actttgtgat
    29041 aattctccaa ttctttttta tcaaagttcc atttggcaat caagagactc cgaatttcag
    29101 ctaatacaga ttcaatccga gatttaatat taggattttg aagagcttcc aaaattgtct
    29161 tggcaccata atgcgcacca atgtaagctg aagttgcatg tccagaattg actgaaaaaa
    29221 gttttcgctc aataaagggt tctaaatctt cttcataatg cacatctttt agacgtaaat
    29281 ctggattttt aagacgcttg gtttccacga cccattcatt aaagggctcg accacaacaa
    29341 aaagggaatc ttcgtgactt tgtgctggaa caatcctgtc tactgcagca tttggaaaac
    29401 ctatgtagtt atcagcaaat gtcaaacctt ccggacttaa atatttcttg acttcttgat
    29461 aaagaaattg agacccgcca atcatatttt cacaggccat aacatccaat acctgtgtat
    29521 tccctgcaac tcggcgagct tcgattcctt tggctagaag ttcagcgata aaagggagta
    29581 tattaggtcc gattgcagta gtaataatat ccgtcttttg aatcgcttca atgacttgct
    29641 caggatgttc tttgctatta attccagcca cattagttac ttctatacga gactgtcctt
    29701 tctgtgcaat ttcaatttca tacttgccct tttcatttag agcatgaatt atctgattat
    29761 tgacatccac aaaatcaata tggaaaccat ttttaaatag aatttcacct ataaaaccac
    29821 gaccgatatt accggcacca aaatgaacag aatgtttcat tcaatttctc cttttcctat
    29881 ttgagggaca tatatactag atggcaaatg acgaaattca attattcaac agcatcaaat
    29941 aagcgcaata cttcctcttt tgactgagca tcggctaatt taagaacatt atctacatct
    30001 gcacagaaga tagaaatttt ctgaataatt tctaagtgtt cattaccaat accagcaata
    30061 ccaaaaagaa ccgttgccac ttgagggtta gatacattcc caaaatcaac ccctctaggg
    30121 acttgaacga ctgtaatacc agacttgagg acatcctttt ttgctgcatc tgttccatgc
    30181 ggtattgcga taaagttacc catgtaaaca gatagctctt tatctcgctc aatcatggct
    30241 tcaatatagt cttcattaac atatccaccc tcataaagaa cttgcccaca ataacaaata
    30301 gcttcctcct tgttagaaaa ttgtttatta agcttaatca aatgtttttc aagtttcata
    30361 ttagttctcc aatttcttaa ttttttcgtt aaaaatagta tttagcatct gataaataat
    30421 ggattgattt cccgtcttgt aaatctctgt ataaagatga ttttcaataa tcgactgact
    30481 aatagctgtc attaaatctc tcgcttcctc gctagcttct ttagacatta gcattagcag
    30541 acaccttttg acctcttctt cctctcgttt cattgacaat gcggagatag gtagtttgag
    30601 ttcaaacata gtaaaactat ttgttgttac tttgctagac tgactatgta aaagcaccag
    30661 accagtatta ggaatagcca taggactatt ctggaagtga gataacaatt ttcttgttag
    30721 gtaatctctg tcactcacat tcttctgata ttggatgatt tgttctaccg tgtgctcaaa
    30781 tgattgatta ttctccaatt gaaccaactc gaattgactc aaaagctgac tactagatat
    30841 taaataatct tgcaagtcat aacttttctc tggagcgata gcatcacgcg cgacaattgt
    30901 acgatgtgcc tgtacatact gaagtcgttc ctgtaattca agcaattctt tgacggttgg
    30961 aaaactagaa attacatcga tttcctgatt agtcagcggc ttggtagata aaatataatc
    31021 atactgactg agatcaatac tgtggtaatc tactagagac tgaatatcta tcaactctac
    31081 aaaaggagca acactcttaa ttttactgac taataaatct ctagtgaccc gacgttcatc
    31141 cgttaaaagc aaaacacgga ctggataaat ctctggacta cggcctaagc tagagataaa
    31201 atgtagggca atcatgccat actcatactc tgtatgaaga tatttcggaa aaatatcatt
    31261 cactaaaaga ctgatgactg tataaagaaa tttattcctt tcaactaaaa tctggacaga
    31321 ttctggcaaa ttttcaccct gaaaaaggat agggacgcct aaactgagcc gaatatgatg
    31381 gaaaagaaaa ttgaataaaa ccttgtcctt aaaaaagtca atcttggtat acatggaaac
    31441 cgtatcaatc agatttgaaa tattgtagaa aaattcacca tcaaatttct ccgtaaagag
    31501 cggattgtcc tgacgtttaa tgattaattc atccaagatg ctcgcaaaat agataatttc
    31561 ctgaatacta taaaattgtg cagtctgctt agagtaagct tgaaaaattt tttgagaaat
    31621 ttccaaagcc tgcttactag tattaggtga attttcaatg ttttgctcct gacctataag
    31681 agataacaag atcgcaaaaa acatcttcat cctagcatcc atatctggaa aacctgacag
    31741 ttgcttatta acaatctgac tggccagcct agttctatct gcttctaaaa tatcaaagct
    31801 cccaaaatta ccggttgaaa aatctgctac tgagatacag tttgtcagta aaatagccaa
    31861 aaatcttctc ttaccaactg aatcaccaga aatccgataa cctttttgtc gttcaatttt
    31921 cagatcaaag tctaaaagac gcttatcaat atctgaaata tcctgaataa tagttacatt
    31981 actgactttc gtgcactctt gcaatgcttc attggtgaca aaaccactct cagtcagaag
    32041 gcgataggta atcaactctt gtctttcttg gggactatac tcaactaaca cttcaagttc
    32101 tgtcggcaaa tcatccaact ctccagtcaa aatatagtat ttcccatgct tcgttatttc
    32161 gattccatat tgctccatgc tatctgtcaa atctgataaa gttcgataaa ttgttctaga
    32221 tgaaacctgt aagatttcag tcatatcttg cattgaaagc ttccctacat gtaggaaagc
    32281 cttcaataat tgttcttctc gtttggttaa tagcattcgt aatttagaaa cctctagttc
    32341 tatttgtaca ttctagcagc cattttgtca tattctggtg ttgttactaa actatccaca
    32401 ataagaaatt gagaattcgg tgctgcttgc tgcacttctg cctgtaaaga aatagttgtt
    32461 acaatcatta tgtttttaga attaaattca cctaattctg aaattttggc agtagaaact
    32521 ggaatacgaa tattcttgtt tctaaagata gcccgaatcg tttcacagcc catagttgca
    32581 gttccctgtg ctttaccata agcaactact acagcatcaa tatggttaag gtcaatttcc
    32641 tgactatcta ctggtgctga agttggtata tctccttcaa tttctgctat tggaaaagct
    32701 cctgttaatg aagctacaat ttcatcataa cgaggggacg ctaagaaatt atcaacagaa
    32761 acatgaatag cacttggact cttgtcttta gctcttggtg tcagttcttc ctgagtaaca
    32821 attaatgttt ttggtgtatc aagcaaattt gagattgcct gattagatac tggaatctct
    32881 agacctgctt ttttaacctt atctcgaaga atactagctc ccatagcaga gcttcccata
    32941 ccagcatcgc aggcgaaaat gattttttcc actgagtctg tcgaaataac tgcatcaaca
    33001 gaagttgata ctaactgacc tttagactga gctttagctg cttgggtagc ctcttgagca
    33061 gcttcgagcg aatcctcagt tgacttgtct gcatgaagaa taagggctgc tacaaagaaa
    33121 gaaacaactg ctgccactaa aacacctaga agaacattta gatggggcca aacacctttt
    33181 ggcgccgtag ccataatcgc aataatagaa cctggtgaag ctggagattt aagaccagcg
    33241 tctaagagtt gaaaagtaaa agttccagag atacctcctg ccatagcagc taaaaataga
    33301 gtaggcttca tcataacata aggaaagtaa atttcatgaa tccctccgaa gaaatgaata
    33361 accattgccc cccaagaaga agatttagca gaacctttac cgaatacagc ataagctaat
    33421 agaattccca ggcctggtcc aggattagct tccaatagga agagaattga cttaccagct
    33481 tgagctacct gttctactcc cagaggagta aaaatgccat gattgagggc attattgagg
    33541 aaaaggactt tagccggttc gatgataata ttagctatag gaaggaggcg agcattgaca
    33601 atagcctcaa caccattccc aacagctcca gtaagagtcg atacgactgg accgattgcg
    33661 tagaaagcca aaagcaataa tgcaaaacca acgagaccag ctgagaagtt attaactaac
    33721 atttcaaatc cgggacgaat tttttcctgg aacttctcat caaatttctt gatagtccat
    33781 cctcccagtg ggcccattac catagctccg ataaacatag gaacactaga acctgtgatt
    33841 gcaccaacag tagcaatagc tcctacaacg gcaccacgtt ggccatggat catatatcca
    33901 cctgtgtaac caatcaggat tggcaataaa tacgttaaca taggaccaac aacagtagct
    33961 aactgttcat ttggcagata gccatcagcg ataaagaggg cagtcaatac tccccaagca
    34021 ataaatgctc caatattggg cataaccata tttgaaagcg atgtccctag tttttgaacc
    34081 ctgactttca atgatacttt ttcttccatt agatcatcct ccttttctta aaactagtat
    34141 atacaaagtt aaaaaccttt aaaactaaag ttttgtcaca aattttgtgt caaaacatta
    34201 cttttgacga ggctgggcaa aaaggcttaa aaatgataaa acgcatcata tccggtgtac
//
LOCUS       DAVKMJ010000027        33886 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000027 DAVKMJ010000000
VERSION     DAVKMJ010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33886
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.027"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(172..534)
                     /locus_tag="VW348_001288"
     CDS             complement(172..534)
                     /locus_tag="VW348_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEU9746184.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFGNE"
     gene            548..622
                     /locus_tag="VW348_001289"
                     /pseudo
     CDS             548..622
                     /locus_tag="VW348_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(894..1052)
                     /locus_tag="VW348_001290"
                     /pseudo
     CDS             complement(894..1052)
                     /locus_tag="VW348_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(1325..2014)
                     /gene="rplA"
                     /locus_tag="VW348_001291"
     CDS             complement(1325..2014)
                     /gene="rplA"
                     /locus_tag="VW348_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEU9746185.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(2222..2647)
                     /gene="rplK"
                     /locus_tag="VW348_001292"
     CDS             complement(2222..2647)
                     /gene="rplK"
                     /locus_tag="VW348_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEU9746186.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            2779..2916
                     /locus_tag="VW348_001293"
     CDS             2779..2916
                     /locus_tag="VW348_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746187.1"
                     /translation="MKIKEQTRKLAAGCSKYSFEVADKTDEVSSKHCFEVVNRTDAVS
                     R"
     gene            complement(2956..3672)
                     /locus_tag="VW348_001294"
     CDS             complement(2956..3672)
                     /locus_tag="VW348_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEU9746188.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKTKNEDGETKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(3675..4145)
                     /locus_tag="VW348_001295"
     CDS             complement(3675..4145)
                     /locus_tag="VW348_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU9746189.1"
                     /translation="MCLICQRIDLIKKEENPYFVKELETGYLVVGDHQYFEGYSLFLA
                     KEHVSELHHLKKETRLRFLEEMSLVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLKGRGPVWWVPFEEMTAETCQAKPDEIKRLVKRLSSEVDKLLEIKE"
     gene            complement(4147..5184)
                     /locus_tag="VW348_001296"
     CDS             complement(4147..5184)
                     /locus_tag="VW348_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEU9746190.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREIADYLVKTLEGFGYQPVRTSK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKMDRIGGFPWNMIEGENCTI
                     HVASTGEKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDAKVTSEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRIYKEEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVIATERM
                     VDAYLKSTLVD"
     gene            complement(5388..6713)
                     /gene="brnQ"
                     /locus_tag="VW348_001297"
     CDS             complement(5388..6713)
                     /gene="brnQ"
                     /locus_tag="VW348_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEU9746191.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(6884..6976)
                     /locus_tag="VW348_001298"
     CDS             complement(6884..6976)
                     /locus_tag="VW348_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU9746192.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(7019..7171)
                     /locus_tag="VW348_001299"
     CDS             complement(7019..7171)
                     /locus_tag="VW348_001299"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEU9746193.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LTDSYD"
     gene            complement(7331..7909)
                     /locus_tag="VW348_001300"
     CDS             complement(7331..7909)
                     /locus_tag="VW348_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEU9746194.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(7963..9363)
                     /gene="pepV"
                     /locus_tag="VW348_001301"
     CDS             complement(7963..9363)
                     /gene="pepV"
                     /locus_tag="VW348_001301"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEU9746195.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGVARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(9376..9981)
                     /locus_tag="VW348_001302"
     CDS             complement(9376..9981)
                     /locus_tag="VW348_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEU9746196.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVCEKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDEKLEPSYRLPVDEIIEKR"
     gene            10152..10952
                     /locus_tag="VW348_001303"
     CDS             10152..10952
                     /locus_tag="VW348_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9746197.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKESSSQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTYLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATIDFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSTDSPSN
                     YIVFSSDQKEFKEKFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(11130..11963)
                     /locus_tag="VW348_001304"
     CDS             complement(11130..11963)
                     /locus_tag="VW348_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEU9746198.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLQGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEVLDGEYGLEYPKEIQSMRMTQFLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSKGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRREDNYQRHNLKLLASLIEKHRYVEDVKNFFDF
                     L"
     gene            complement(11953..13797)
                     /gene="uvrC"
                     /locus_tag="VW348_001305"
     CDS             complement(11953..13797)
                     /gene="uvrC"
                     /locus_tag="VW348_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEU9746199.1"
                     /translation="MNNLIKPKLELLPTSPGCYIYKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNEHYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKNDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVTAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(13836..14537)
                     /locus_tag="VW348_001306"
     CDS             complement(13836..14537)
                     /locus_tag="VW348_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEU9746200.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWPQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETNE"
     gene            complement(14616..15848)
                     /gene="murN"
                     /locus_tag="VW348_001307"
     CDS             complement(14616..15848)
                     /gene="murN"
                     /locus_tag="VW348_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEU9746201.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQNKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15853..17073)
                     /gene="murM"
                     /locus_tag="VW348_001308"
     CDS             complement(15853..17073)
                     /gene="murM"
                     /locus_tag="VW348_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEU9746202.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(17185..17964)
                     /locus_tag="VW348_001309"
     CDS             complement(17185..17964)
                     /locus_tag="VW348_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEU9746203.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALTTNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(18033..19694)
                     /locus_tag="VW348_001310"
     CDS             complement(18033..19694)
                     /locus_tag="VW348_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU9746204.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(19869..22091)
                     /gene="recJ"
                     /locus_tag="VW348_001311"
     CDS             complement(19869..22091)
                     /gene="recJ"
                     /locus_tag="VW348_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEU9746205.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            22368..23126
                     /locus_tag="VW348_001312"
     CDS             22368..23126
                     /locus_tag="VW348_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9746206.1"
                     /translation="MVLVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAKKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLARDRMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            23166..23930
                     /locus_tag="VW348_001313"
     CDS             23166..23930
                     /locus_tag="VW348_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU9746207.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTNKRTALLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            23943..24620
                     /locus_tag="VW348_001314"
     CDS             23943..24620
                     /locus_tag="VW348_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9746208.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLITLPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGATLLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            24630..25289
                     /locus_tag="VW348_001315"
     CDS             24630..25289
                     /locus_tag="VW348_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9746209.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLCILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            25547..26737
                     /locus_tag="VW348_001316"
     CDS             25547..26737
                     /locus_tag="VW348_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEU9746210.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHSLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(27058..27939)
                     /locus_tag="VW348_001317"
     CDS             complement(27058..27939)
                     /locus_tag="VW348_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEU9746211.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(28078..29406)
                     /gene="vncS"
                     /locus_tag="VW348_001318"
     CDS             complement(28078..29406)
                     /gene="vncS"
                     /locus_tag="VW348_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEU9746212.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(29403..30059)
                     /gene="vncR"
                     /locus_tag="VW348_001319"
     CDS             complement(29403..30059)
                     /gene="vncR"
                     /locus_tag="VW348_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEU9746213.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(30108..30191)
                     /gene="pep27"
                     /locus_tag="VW348_001320"
     CDS             complement(30108..30191)
                     /gene="pep27"
                     /locus_tag="VW348_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEU9746214.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(30371..31750)
                     /gene="vex3"
                     /locus_tag="VW348_001321"
     CDS             complement(30371..31750)
                     /gene="vex3"
                     /locus_tag="VW348_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEU9746215.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(31802..32449)
                     /gene="vex2"
                     /locus_tag="VW348_001322"
     CDS             complement(31802..32449)
                     /gene="vex2"
                     /locus_tag="VW348_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEU9746216.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(32462..33739)
                     /locus_tag="VW348_001323"
     CDS             complement(32462..33739)
                     /locus_tag="VW348_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9746217.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNAITTYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9626 a         7710 c         6325 g        10225 t
ORIGIN      
        1 caattgtttc gtactatttt agattcagtc tactatacat aaactaacct cctcattatt
       61 agcaaggatt ctactgatta taacctaatt cttagactac ttcaagacta actgtccaat
      121 aataatctac agataaatca tccactctta ataaaatttt attcaatcca tctactcatt
      181 cccaaaaggt tgagatttat ctagtaactc taaaacatta atggtaggta gcaacattgc
      241 ttcactgcta tcaattgccg aaactattga aacaatagaa cgtaaataat gataaagaat
      301 agcagtacca tttacgtata gaatatcggt gatattttca tctatattta tttcaaaata
      361 tcctattaca gttacagata tttttttcat ggcatctttg tcaactaaag aaacactaag
      421 ttttacggct ccatgactat aatcatctgt atgaccaacc ttaactatgg gatataatat
      481 atcgaaggta aatgtgaaca aactgattag gaaatttaaa ccaacttcta acaatctgtt
      541 atactcaatg aaaaccaaag agcaaactag gaaactagcc tcaggttgct caaaacactg
      601 ttttgaggtt gtagatggaa ctgacgtagt cagatcaaaa cactgttttg aggttgtgga
      661 tagaactgac gtagtcagct caaaacactg ttttgaggtt gtggatagaa ctgacgtagt
      721 cagtaaccat acgcacggca aggcgacgtt gacgtggttt gaagagattt tcgaagagta
      781 ttagaaagct cgatgaacta ttccagattc attccactaa atttcgaaat cgagtagggg
      841 ataatctcta gcccctctca caccaccgta cgtgccgttc ggcatacggc ggttcaacta
      901 acttttaacg catgtcgttc aaggtaataa tccaaacacg aaaccagtcc acgtttttca
      961 aggactggtt ttgatatagc acgtttaagt accgacttct gagctactaa ttgatagtgg
     1021 tcgccccagc cagatacctt atccgctata taggccttat tatcacgttc ctgttcgtag
     1081 agccacgatt tcgctatccc ttcctctgac gattcttatt tccagcgtca gacttaaaac
     1141 ggtctatccc cagaccgttt taatccgcta cctcacgata gtcagacttg ggaatcgcta
     1201 ttgggttcac cggtagtagg tgcccaccga ggacttacac ctcagatata cgacatgccc
     1261 gtcgtacatc aaaaaaagtt gagacatagt gtcttcaact tttttacatt actttaacta
     1321 ctgattaaag tgagtttacg tcaactttga taccaacacc ttgagtagtt gtgatagtca
     1381 agtttgttac gtaagttcct ttagctgtag ctggttttgc tttttggatt gtttcgttga
     1441 aagctttaaa gttttcaacc aatttttcag cttcaaatga tactttaccg atgattgctt
     1501 gaacgttacc tgcacggtca gcacggtaag tgattttacc acctttagac tcttcaactg
     1561 ctttagcaac atccattgtt acagtaccag ttttagggtt tggcatcaag ttacgtggtc
     1621 caaggacacg tccaagacgt ccaacaagag ccatcatatc aggtgtagcg ataactacgt
     1681 cgaagtccaa ccaaccgtcg ttgattttag caacaaggtc atcttcacca acaaagtctg
     1741 caccagcagc ttttgcttct tcagcttttg caccacgtgc gaaaacaaga acacgtgaag
     1801 ttttaccagt accgtttggc aataccattg ctccacggat ttgttggtca gcttttttaa
     1861 cgtcgatgtt caagttgtaa gcaacttcta cagttgcatc aaattttgca aagttagttt
     1921 cttttgcaag tgctacagct tcttctacac tgtatgcttt tgtgctgtcg attttctcaa
     1981 gagcagcacg aagttgtttg ctttttttag ccattttcta ttctccttgt aagtggttca
     2041 atcgattttc atctcccacg tcacttctcg aaatgatgaa gtcttgcggg ttttcagtct
     2101 actatttttc tcttcctacg gccttaagct cccttgctgt acccaagtac aagcctcagt
     2161 cacttgccta gtatgaaaag caactaatag actgctgtga gattttctac tgtgttattg
     2221 attagtcaac aacagtgaat cccatagaac gagcagtacc ttcgatcata cgcattgcag
     2281 actctacgtt tgctgcgttc aaatctggca tcttagtttc tgcaatttct tgtacttgtg
     2341 cacgagtaac tgtagcaact ttagttttat taggtgtacc tgatcctttt tcaacacctg
     2401 cagctttttt caaaagaaca gcagctggtg gtgttttcgt aacgaaagta aatgatttat
     2461 cttcgtaaac tgagataaca actggaatga tcataccagc ttggtcagct gtacgagcgt
     2521 tgaactcttt tgtgaatccc atgatgttga taccagcttg accaagagca ggtccaaccg
     2581 gtggagctgg tgtagcttta ccagcaggga tttgcaattt tacaagtttt tcgacttttt
     2641 tagccatttt taaatcctcc tttgtggttt tggcggtaat tagagatttt tacctcccac
     2701 aagtatgttt ttcacatacc catccattat acactattta tctggaattg caagagaaaa
     2761 gtttattttt tgtactcaat gaaaatcaaa gagcaaacta ggaagctagc cgcaggctgc
     2821 tcaaagtaca gctttgaggt tgcagataaa actgacgaag tcagctcaaa acactgtttt
     2881 gaggttgtga atagaaccga cgcagtcagt aggtaaggcg acgctgacgt ggtttgaaga
     2941 gattttcgaa gagtattaat cgacgtagtc tccgccttca aagccatagt attcttccaa
     3001 actgagacca cttgcagcaa tttctttagc ttcttttcct acataacgca ggtgccattc
     3061 ttcagccata tagcctgttt ccttttcctt gcctttgaga taacggacaa caaagccata
     3121 atcagctgca tgatccaaga gccattgggc tgctttttct tctgtcacca aatcaccatc
     3181 agtcccaatc acatcaaagg ccaagcctgt ctggtgttcg ctatagccag gacgggcaga
     3241 gtaacggtca gctgctgcct ttccatcttg gttgacataa tcttgataga gcttggtctg
     3301 agtttcataa cttctaaaac cactgtaatg atcactaata gggaaacctg cctcttgcat
     3361 cgctttgatg agtttgacca actctgcctt ggctgttgga ttttcccctg gattatagtc
     3421 tttagacaat ggatagtgtt tgttggctac gatgatttca tcgtatttcc cttgaatgct
     3481 gtagtaatca cctttattga ccacttctgc tttcttctgg gcagctcctt gagacttact
     3541 accgactgtt ccatcagctt tggctgtctg ttctgtctta gtttctccat cttcattttt
     3601 tgttttttct tgtgaacaag ctgctagact caaggctagc aaagctgtca agactaggta
     3661 tcttttcttc atttctactc ctttatttct aatagtttat ctacttctga cgataaacgt
     3721 ttgactaatc ttttaatctc atccggtttt gcttggcagg tttctgctgt catttcttca
     3781 aagggaaccc accagactgg tccacgaccc ttgagaccat gaccattcat atcacctgtc
     3841 cgtcgtggaa acagatgcca atgaagatga gcatcgccat ttcctagcag ttcgatattc
     3901 attttctcag cagcaaaggc cttggcaact gcctcttgga ctaaactcat ttcttctaga
     3961 aaacggagtc ttgtctcctt tttcaaatgg tgcaattcgc tgacatgctc cttggctaga
     4021 aagagactat agccttcaaa atactggtgg tctccaacca caagatagcc tgtttccaac
     4081 tctttgacaa agtaaggatt ttcttccttc ttgatgaggt caattctctg acaaataagg
     4141 cacatattag tccaccaacg tgctcttaag ataagcatcg accattcgtt ctgttgcgat
     4201 caccgagtca atatgggtac gctcatagga atggctagac tctataccag caccgagaag
     4261 ggcgtgtttg acttctgccc ctgcagacat agccgctgaa gcgtccgaac cataaaatgg
     4321 atagatatcc agcttaaatg gaatatcttg ctctttcgcc aaagccacca aatgttgacg
     4381 gaagtcatag tgataaggtc cagaagcatc cttgacacag atagacactg tatattcgtc
     4441 tgtttgctgg tcatctccca tggctcccat atccacagcc agatattcta ctacctgagc
     4501 aggaatgtta gagtttgcac cgtgtcccac ttcttcaaag actgaaaaag caaaatgagt
     4561 tgttacgggc aattcaatct tctcttcctt ataaatgcga aggagattga gcaaaatcgc
     4621 cgcactgacc ttgtcatcca aatggcgaga cttgataaaa cctgtctctg tcacgacagt
     4681 tcgtgggtca aaactgataa aatcaccgac ctcaatgcca agagcacgag tttctttttc
     4741 actagttact ttggcgtcca aacgcacttc catattgtct tgcgtgcgtt ctgcagttcc
     4801 tgcatcctta tagacatggc aagaagtttg gtggatgagg atggttcctg atactttttc
     4861 acctgtgcta gccacatgaa tggtacagtt ttctccttca atcatgttcc aaggaaagcc
     4921 accgatacgg tccattttga gacggccgtc tggtttgaca gcacggacaa tagcaccaag
     4981 cgtatctaca tgggcagtca catagcgatg ttgctcatca ttttgacctt taatagttac
     5041 attgacaccg cccttggatg tgcgaaccgg ctggtaacca aaaccttcta gagtcttaac
     5101 taaatagtcc gcaatctcac gagtaaagcc tgttggcgac gcaatggctg tcagttcttt
     5161 gatatattct actgtttgat tcatttcttc acctcttttg ctacctatta taacacattt
     5221 atcatcggat aaaaaaagaa aatcactcct gtagacttga ctacaaaagt gattttatac
     5281 tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gctgtacttg agtacgacaa
     5341 ggcgacgttg acgcggtttg aatttgattt tcgaagagta ttagtgatta ttccatttca
     5401 aaaacatcgc tttcttgctt gtttggtaga accaatgaga gcaagattcc aacaatggct
     5461 ggcaccaacc atgggagaga tgccttggca aaaggaagaa cgctaacaag atttgcaaga
     5521 aactcaacct taaacgagct tcctagtacg cttgcaatgg caataactgt aaccacagca
     5581 attgtcaact gcatacctgg ttttgaaaga gcaacaaatt tgttgacaat gacaatcata
     5641 acgatagcaa tcgtgattgg gtacaagata accagtactg gaattgagta cttgataatc
     5701 gcatcaagac ccaaattggc aatagcaaat ccaatcaagg taaaggctgt cgcataaacc
     5761 ttgtagctga tttgtgggaa gcgctcatta aagaactcag ctgttgacac aatcaaacca
     5821 acagtcgttg tgaagcaggt tacggtaacc atagctgcaa ggaagagttg agctgttgag
     5881 ccaaagattt cttgagtggc ttgtgacaag atgtaaacac ctggtgttcc acccttcatc
     5941 gcttcagctg gtactgggaa atgatttcca agaaaaccta aaccgatgta aagagcgctg
     6001 aaggcaaggg caacaacgat accaacaacc caaatagttg aaatgtattc tttcttactt
     6061 gaaaatccaa gttgtttcaa ggtttgaact gcgattacgc taaaggccac tgaggcaagg
     6121 gcgtccaagg tattgtaacc ttctaggaaa cctgtaccaa aggcagaagc ttgataagca
     6181 gctgaagcag cttgaggact tgttccacca tatttgatag ctcccagaac gaccaagata
     6241 acaatcaaaa ttgcaaagac tggcgttaaa atacgtccaa tgcggtctaa gatttttgat
     6301 ggattaagcg aaatcaaata ggctgccgca aaatacagaa ccgtaaatac aatcaagcca
     6361 agtcctttat ttgcatccga caaaaggggg ctaatcccta cttcgtaagc tgttgtagca
     6421 gtacgtgggg tagcaaagaa tggaccgatt gacaagtaaa gaactgagag gtaaagagtc
     6481 gcaaaccaag gcgctatctt cgttgaaatc tcgtagatat accctttagg atttagcgtt
     6541 ccaataataa gggtcaagac ggcgatacca acgcctgaaa agacaaaacc tgcgatggca
     6601 ggaagaaaat gttctccaga tagagcacct agagaaggcg gaaaaatcaa gttccccgca
     6661 ccaaaaaata ttccaaacag gagcaaacct gttagggtac cttttttagc cataaaaatc
     6721 tccttcatat ttataaaata ctgacctagt ataccacgat taggagtctg aaaaaagcat
     6781 cacgaggcaa atattaaatg ttttcaattt tcttaaaaat aagaattatc taaaaataaa
     6841 actctcctac ccagtccaca ccaagtagga gaaatgcaaa attttaaagt tcttcaaagg
     6901 ctaacatgcc accctggaca ttgataacat tataaccttg ttctaacagg aattggcaag
     6961 cacgcgccga tctcattcca gatttgcaaa taatataatg caagcgatct ttgtccaatt
     7021 aatcataact atcagtcaat tgactaagcg gtaggttgtg ggcaccttct aaatgaagag
     7081 ctgcaaactc atccacttct ctcacatcca ctagagaaag ctggtcgttt tggtaaagct
     7141 ggtaaaatgc gtcaaaggct atttctttca ttctttttct tctaatactc ttcgaaaatc
     7201 tcttcaaacc acgtcagcgt cgccttaccg tgcgtatgtt accgacttcg tcagttttat
     7261 ctgcaacctc aaagctgtac tttgagcagc ctacgactag cttcctagtt tgctctttga
     7321 ttttcattga ctataaaatg gttttaattc tttttttcaa atctggcact acttctgcct
     7381 caaaccaagg atttttggcc atccagattt gatttcgtgg tgatgggtga actagcggaa
     7441 aataggctgg cagatagtct ttatagtgtt tcaccctctc cgttaccttc ccactgattt
     7501 tctcctgtaa atagtaggct tgggcatatt gcccaatcaa gagggttaac tgaatatcag
     7561 gcaattcctg taagagctgc ggatgccatt tttctgcaaa acctgtacga ggcggaagat
     7621 cacccgactt gccatgtcct ggaaagtaga aatccatagg caaaacagca aaataacctg
     7681 aattgtaaaa ggtatcttca tccacaccta gccagtcccg caagcggtca ccacttttat
     7741 ctttccagta aaggcctgct tcttgagttt taagtcccgg agcctgaccg atgatattga
     7801 tgcgagcagt ttttggcgct gcaaagagag gctcaatgcc acgctctgta tagctggcat
     7861 tctgtgaatc cgccatgata gcctgtttga ttctttcgat ttgagacatc tactttccct
     7921 ccaaaaagaa gtccaagcat aagatctcag acttctatcg ttttatttga tcaattcgta
     7981 aatagcttcg gcataaattg ctgctgctcg gaaaagatca tccaaggcga taaattcatt
     8041 ggcttggtgc atggtatcaa tcgagtctgg gaacatagca ccgtaggcaa ctccgcgttc
     8101 tagcaagcga ccaaaggttc caccaccgat gacttgttca tgacctttaa ggccagtttg
     8161 tttttcatag atattcaaca aggtttgcac aagtggatct tccattggca catagtgagg
     8221 cgtgtgaccg tgttcagaca ggctaacaga aacaactggc aagttttcaa ggattgactt
     8281 gatttgttct ggacttgttc cttttggata gcggatgttg agggcaatgg tattatcagc
     8341 acttgtttca tcgaagcgga agacgccggc attcatagaa agagcaccca tcttttcatc
     8401 cacatgagca atcttaagat tttcaccctc atgatcgttc aagagaattt tacctgcgat
     8461 gtcaaggtag tctttggctg gaccagcaaa gccaaactgg ctgaggaaga gggcaaggta
     8521 agttgcgcca ttgacacctg aagcaggcat agcaccgtgg gctgatttac caatgatcgt
     8581 caccttgtat ttgccagctt cttcttggag ttctcctcta agtttgtgtt ctgcaacaaa
     8641 ggcatctagt ttagcttgca agtcagccaa gtcacctgaa acgactgctg ttgctgattc
     8701 tggtaccata ttttcacgta aaccacctgt aaagctgtga agacgggcaa cacctgtatt
     8761 ttctcctgca aagtggaggt attccgtgat atttcctttt tcaccattga tgattggaaa
     8821 ttcagcatct ggtgagaaac cgaaatctgg tttggcaagt cctacgtgct caaagtagta
     8881 gtccatgtct gcccagcctg attcttcgtc tgttccaacg atgaagcgaa ctttcttaga
     8941 agttggaaga cccaattctt tgatgatttt caaaccatag taacaagctg ttgtaggacc
     9001 cttatcgtcc gaagccccgc gcgcataaag gcgaccatct ttgatagttg gtgtgtaagg
     9061 gtctgtgtcc caaccgctac cagcaggcac cacatccata tgggcaaaga ttccgagaac
     9121 ttcttctcca tcaccaaact caaaatgtcc tgcatagtta tcaacattct tagttgggta
     9181 gccatcgcgg tctgcgattt caaggaattt ctccaaggct tttactggac caggcccaaa
     9241 tggatgctgg gcatcagcct tgctgtcatc acgttctgaa ttgatttcca aaaggctaaa
     9301 caagtcagcc aagaggtctt ctttgcgttt ttctacttct gctgtaaaat caattgctgt
     9361 cattttttct tctttctatc ttttctcgat gatttcatct actggcaagc ggtagcttgg
     9421 ttccaatttt tcgtctgtat aacccactgt gatcaagagt tctgggcgga aacggtcttc
     9481 gatttccaaa acttcattaa cttttgattt gtcaaaacca aggataatat tggaaccaat
     9541 tccttggtct gtaagagcga gaaccaagtt catagcaacc aaacctgcat tgagtgctag
     9601 gtagtcgctg acttgttgtt cattgtagcg tgcaaattca gctggcaaat ttttcatgaa
     9661 gtattgaagt tgttcttctg agaaattgtt agcaccacca actcgggcaa tcttacgagc
     9721 gcgtttggca aggtctgtat ctgtaaatag ggcaatggtt acaggtgctg atgatacctg
     9781 ttcaaaattg gaaccataag ctaactttgc cagttcagca tttttctcac ataccaccac
     9841 aaatttccaa ggctggctgt tgtgggcgct tggcgccaag gttgcaattt cgatagccgt
     9901 acgcacatct tttggatcaa caggcttatc agtgaaatgc ttggtcgcat gacgtttttt
     9961 atttaattca agaaatttca taatcgattt ccttttctaa ttctactgct tccattctac
    10021 cataatttga aagagcttgc agggattttt catgattaag tttttctatc acagacataa
    10081 aagatatata ttggtttatc aggaaagttt ctgataaact agcaagtact ttacatttga
    10141 atggagacag tatgaaaaaa tttagcctat tactagctat cctaccattt ttggttgcct
    10201 gtgggaatca agctacaccc aaagagtcca gctctcaaaa gacaatcgtc cttgctacag
    10261 ctggcgatgt gccaccattt gactacgaag acaagggcaa tctgacaggc ttcgatatcg
    10321 aagtcctaaa agcagtggat gaaaaactca gcgattacga gattcaattc caaagaactg
    10381 cttgggagag catcttccca ggacttgatt ctggtcacta tcaagcagca gctaataatt
    10441 tgagttacac aaaagagcgc gctgaaaaat acctctactc gcttccaatt tccaacaatc
    10501 ccctcgtcct tgtcagcaac aagaaaaatc ctttgactta tcttgaccag atcgctggta
    10561 aaacaacaca agaggatacc ggaacttcta acgctcaatt catcaataac tggaatcaga
    10621 aacacactga taatcccgct acaattgatt tttctggtga ggatattggt aaacgaatcc
    10681 tagaccttgc taacggagag tttgatttcc tagtttttga caaggtatcc gttcaaaaga
    10741 ttatcaagga ccgtggttta gacctctcag tcgttgattt accttctaca gatagcccca
    10801 gcaactatat cgttttctca agtgaccaaa aagagtttaa agagaaattt gataaagcgc
    10861 tcaaagaact ctatcaagac ggaacccttg aaaaactcag caatacctat ctaggtggtt
    10921 cttacctccc agatcaatct cagttacaat aacactcttc gaaaatctct tcaaaccacg
    10981 tcagctttat ctgcaacctc aaagctgtgc tttgagcaac ctacggctag cttcctagtt
    11041 tgctctttga ttttcattga gtataagata tataaaagcg attggactac caatcgtttt
    11101 tagtttgcat tggttatttt aggaaactct tacaaaaaat caaaaaaatt cttcacatcc
    11161 tctacatacc tatgcttttc tattaagctt gctaatagtt tcagattgtg cctctgatag
    11221 ttatcttcac gacgtagttc ttcatacatt tcgataaagg gaagcccctt ggatttggcc
    11281 aattctaact cagcctcgta atcataagca actttacgaa attggatatt gagtaattcc
    11341 ccatcttcaa cctctatcac ggcatactgg gcacggtgat tttttaacgc ctcccaatta
    11401 aaatagggca tgccaatcga ccctggattg atgatttgtt gccctttact gccgtagcga
    11461 agcaactgct tgtgaacatg accataaact gccacgtccg tttccgcatc tagcagttgg
    11521 tcaaatttct ctgtatcatt ctcaactagc aagtcaccac catagttttt gtcaggtaaa
    11581 ttatgagaga tagaaaagcg caatccgtca atttctttct tttccagcaa aggcaagctt
    11641 cgtagccaga caatcgttgc aggatccatt cgctccatca aaaactgggt catgcgcatt
    11701 gactggattt ctttcggata ttccaaacca tattcgccat ccaagacctc aaggacacga
    11761 tcatcccaat tgcctcgaac acttgctgtg ataggaaggt cctttagcag ggcgactaag
    11821 tcatttgcgc ctggaccagg aagaaaaata tctccctgaa gccaatattc actggcccct
    11881 tgatttttag catctgcaat cactgcttct agcgccgtcg cattgccatg aacatctgat
    11941 aaaattgcga ttttatggtt cattgtggtt tccttccgtt tggtaatcta ctctttcttc
    12001 tgctacttga ggcaaggctt ctccctgcgg gttcaacttt ctttgcacag cctctgcaac
    12061 gactctaggt accccaactt cgacaatctc atccacactg gcttccttga ttttggtcaa
    12121 agacttgaaa tgcttcataa gattctgctt gcgtttaggt cccagaccgt caatcccatc
    12181 caattgagat gagaaagaat ttttggagcg cagttggcgg tggaaagtga tagcaaagcg
    12241 gtgcacctca tcttggatgc gttggaggag gaaaaattcc tgagaattgc gagacaagtc
    12301 caccacctca agcggatctc caaagagcaa ttcatgggtt tggtgcttat cattcttttg
    12361 cagcccagca attggaatat ccaagcccag ttcctcttgg atgacttgct tagcaatatt
    12421 gacttgacct tgccccccat caatcacaat caaatctgga ggagtcaaag cctcacgctg
    12481 tactcgacca tagcgtctgc gaatgacttc tctcatacta gcatagtcgt ccggcccaac
    12541 aacggttttt atcttgtact tacggtaatc ttttttactt ggcctgccgt taacaaagac
    12601 caccatggct gaaacaggac tggtccccat gatgttggag ttatcgaagg actcgatgcg
    12661 aactggagtc ggaatttgga gcaaacgtcc tagattttca atagctcctt gggtcttttc
    12721 gactgatttt tctagcagat tgaacttctg ctctagacta acacgagcat tttttatggc
    12781 tagattgacc agctgttttt tctctccacg ttggggtttg agaatcttgg tatccaccaa
    12841 agccttgaca gcttcttcgt caatatcctg cggaatcagt acctcattgg gaactaggtg
    12901 agatttttct tgatagaatt gtcccacata ggtcaagaaa tcctcatctg gatcattgaa
    12961 gtaggggaag agattgacat cgcgctcgat gagcttgccc tgacgaacaa agaaaacctg
    13021 cacacacatc cagcccttat ccacatagta gccaaagaca tcgcgatttt ggagatcctt
    13081 agccatgacc cgttgcttgg ttcgaagtgt tccaatggcc tgaatcaggt cacggtattc
    13141 cgctgcccgt tcaaactcca tactttgtgc tgttactgcc attttactct tgagatcatc
    13201 gatgattttg tcatcctgac ctttcagaaa atcagacacc tcctgggcca tggacttgaa
    13261 ataggcctcg tcattcttac agatggtgtg ggccatacat tggccgatat ggtagtaaaa
    13321 acagacctta gagggcgggt tggtacattt tcgaaaaggg aaaatcctat ctagaagtcg
    13381 cttgatttca ttggctgccc ccacatctgg ataagggcca aaataaagac caccgtcctt
    13441 tttgacctga cgagtaatga taagccgtgg atagtgctca ttggtgattt tgataaaagg
    13501 ataagacttg tcatccttga gcatgatatt gtacttgggc ttattttcct tgatcaggtt
    13561 gatttccagc agaagcgcct caatattaga ctccgtaaca ataaattcaa aatccacaat
    13621 ttcagacacc aaggcctctg ttttggtatc atgacttcca cggaaataag acctcacgcg
    13681 attacgcaga tttttagcct ttcctacata gataatggtg ccgtttttat ccttgtaaat
    13741 gtagcaacca gggctggtcg gcaagagctc tagttttggt ttaatcaagt tgttcatagt
    13801 tccattatag caaaaaagta gggaaagata gtaccctact cattagtctc atatattttt
    13861 cggaggtttg caacatcctc ttcctggata ccataaaagg aacctgctgg ttgcatgaca
    13921 gacttctcat ctgtatggtc caagccaatc gcatgaccta actcatgttc tgccgtatgg
    13981 acaaggcgtt cataggaata gccatagtat ggattggaca aataataatg attcaaccgc
    14041 accgttacgg acaagaattg ccctgttaag agattagttt gactttccgc ctctcctgcc
    14101 acaggagtgc ctccgtcgtt catctccgta gccgtaatat ccgccttact agactcagtc
    14161 acgagttcaa agttaaaagc accagtttga ttccagttct ggattgcttc taaataagcc
    14221 tcttgaaagc gtgaatccat ctgcggatcc aggtaaatac gagcagaggc ctgtggccac
    14281 cttccttcag aatgctggtg actatctgtc tggcttaact taggcagttg ccctgttttc
    14341 tcccattggt caatactttg ttgaccaatt tttactgacc gttctgcttg ctttagcgct
    14401 ccttgaaaat ccccgttcag ataccagaga agtccgaaag caagcacaca taagagcaca
    14461 actatccaaa ccagacgcca aaacaaacgc cacacaaaag aaaagaaagc ccctatcaaa
    14521 cgaaaaagcc agcgcatgtc tctccacctt tctagcaaat aaaaattatt ttactaaaag
    14581 aagctaaaag aaatctaaat actgactttt tcatcttaac gtcctactat ttttttgagt
    14641 aactggatag ctttgtattt taaaggagat ggatggtaac ggaaagtacc tgctttgcgt
    14701 acaatatagc cattaaaatt ctgtttaaaa cgcaaaacac catcacttcc atcaaaaatc
    14761 ccttgaatgc ctaggaagtt gtatttaggt attccacgtt ttatgctttc caacataaca
    14821 tatttttgaa gcagtgcagg ggcatagaac ttattaaact cagtgtagga accactaaag
    14881 agataagtcg tttcctgagg catataaaca aataaactcc cagctaaaac aatatcttct
    14941 tctccatatt tttcaatcaa gtctcgcgct tctgcttttc gaacttcaaa cgtttcaaat
    15001 tgactagaat attctctcag ttgattttgt tttttctcag aatgaggatt tttactcaaa
    15061 tcaagtcgca acttgtccaa gttttcttct agtttatttt gttcaccttg caatttgctc
    15121 atatagtccg aaaaatttaa gcttgctatg agaaactccg cttgttctcc aaaagtatca
    15181 taaaaatgct cataatattc taaactttta tcactatatt ctctacgttc agaggtttct
    15241 tttgttatat tcttaaaaat cgatagttct tcacgtttta actttttcaa tcgaatgcca
    15301 aaggtttcag cctttttcac caagggttta ccctttttgc taaaactttt aagcaaactc
    15361 ttttcagtta attcagttaa atctttatag tataaccaat ctggttctcc acctgggtaa
    15421 cctgttgtta agccatcaaa ttgataacct aaatcagtca aaccttgaat aatacttttt
    15481 ttctcagcat ctattggatt accttggcta tcaaaagttt gataagtttc ataaggtttt
    15541 acaagcaact ctaatacacc attttgcttg gcatattctt ttaactctgc ataaaaaact
    15601 ggaagagcat cttgttgggt ataaatcggc cccgaattga gttccatatg cagaccaccc
    15661 agcatgggca agctataaac cagagctgca acttgaattt ctccttcttg tttcaaagca
    15721 agataaacaa ttcgagcccc tcttttttct agcaaatccc ccatctggac agattgcata
    15781 aaggaacgag aagaaacctg atcagaataa gtctgaaact cttctttcgt gagtgttgtt
    15841 agtgccatat acttactttc tatgtttttt tcttaatgtt ttacggaaat caagagcaag
    15901 tcttaacaga ggatagagag gatgagtggg cattgtaaat tcacccaagt attcttcaat
    15961 cgttggatta aatttttcct taaaatgata aagtccacca ttgagagagt tttcaacacc
    16021 acctaaattt tgccagacca tacctcgctc aaaggcatag cgagccgttt cataccatgt
    16081 taaaattggt gcattgtaac gtttaaaatc atcatccata ccagcatata tattgacaga
    16141 ggtagtacca aattccaaac tcaaagtagc cgctaaagga actctcgctt gacctacatc
    16201 tatatattcc tgcaagaagg tcaattcctc taacaaacgt tctttttcct tcttctgcgc
    16261 ttctactttt gaagttcgag tcgactcagt aaaggtctct tccaaggctc tatttttcgc
    16321 taactgttct tctaattctt gcgaacgttt agaaacatcc aaggtggcca aggtgatata
    16381 ggccttgtcc ttaaaattat ctaacaattt tttataatag gcttcattcc tcaaatgaat
    16441 ctcttttcgc ttctcagttt ttttcatcaa ctccgaaaat gaatctaata gttccagtcc
    16501 accatattga atctcaagcc ctttgtttcg tgctgttcga atagcctgtt ttgttgactt
    16561 ggaaagttta tcttcttcaa aattttcctt gtatattttc gcctgaatac gaggttgaat
    16621 ggtgtctccc atttcctccg tttttcctga ccaccttact cccatttgtt gcaaactatc
    16681 aataatagcc agattttcag gaaattctgt cttttcctga ttgattaaac tttgagatag
    16741 gcaaatactt gggtcaaaag tcacaaaaac cgctctctta ctgcgagcat aggacttaat
    16801 agactgaatg gcaaaattca agagttcttt atccccataa tccaatatag gtcctcttgg
    16861 gatgtaaaac attttatagc ctagcggaag agttctaatc aaaatactag ctgtcgccag
    16921 taatttttct tccctgtaaa caccaaactt ctcatgttgc caattagact taacttcctc
    16981 ccaagcacta ctttgtaata cattggctaa ttcatgttct ttgacaaact gatcatattc
    17041 taatgtggga atgccaattt gataacggta catttcctac tctctttcct ccagtatttt
    17101 attactattc tactactttc gtttgaaaag tctagtgaaa acatatttta ttttagttct
    17161 actcccccta tgctgaagtt caaactaagt cagtctctct tctaatttga aatcaattgg
    17221 tagggttgtt aaaaaaactt ccaattgttt ttcccagtag taccactcgt gagttccagc
    17281 actatggcta taggtcacat caaaacctag ttttttgaga tttttcactg cgagattatt
    17341 ggcttcgtac aagaaatcct gttcgccaca ccacgcccaa agtttggtct ttttatccga
    17401 ttttttagcc agactttcaa gagaataggg actagttgtc cagtctctaa tctctccaaa
    17461 aacacctctc cagtaggctg gacttcccag attttgactt tcaggagaaa agttttgaaa
    17521 gctgagggca cctgaaaaac tagctgcatg agaaaaacga tttgtcgtaa gagccagttt
    17581 gaagcagccg tagcctccca tagaaagacc agcgataaag gtcttttcac gcttgctagt
    17641 catattaggg aagaagcgtt tcagaacctg tggcaattcc tctgctagag ccgtgtagta
    17701 gtcaaaacca tactgggtat cggtgtacca accattgctg gtattgggca taacaacgat
    17761 gagattagtt cctcgaagca agcgttctac attggtccgc ttaagccaac tattatgatt
    17821 tccagacatc ccgtgcaaaa ggtacaagac gggaatatct tcacactctg gttcttccac
    17881 tcgattggca tcagggtaga ggacattcac cccccactcc atatccaata cttgtgagta
    17941 atactcgatt ttcattactg ccatgatttt ctccttctat ttttctataa gaaaaagccg
    18001 aaactcgact ttctctctgt ttatttcaac gattattttg cttccatgac tactggtaaa
    18061 atagctggac gacgcttggt ttggtcaaag agatacttgg tcaaattatc tcgaaccttc
    18121 cctttaagat ctgcccagtc aaagtcatct ccttgaagat aatcttctac cgtttggtta
    18181 atcaattctg aactttcacg gagaatatcg cgactcttct tgagataaac aaatccacgc
    18241 gtgtgaacac gagccctagc cacaattttc ttctcacgac ggttgactgt aatagccacg
    18301 atgaaaattc catcctctga caagacctta cggtcacgaa gaacaacatt tccaacatca
    18361 ccaatggcat tcccatcaat caagatatct cctgctgaaa ccgatccagc tggaacaaag
    18421 tctccattct cgtaagccat ggtcgtcccc tttttaggaa tgaaaatgcg ttctggcaac
    18481 atcccaactg ccatggcagc cttagcgtga gcatccaact cacgatactc cccttggaca
    18541 gggaagaggt acttaggttg caaaagattg atcatcagct gcaaatcacg cacatttccg
    18601 tgccctgata catgtaaact ttgggtaatc aatttgacaa ccccacctgc ctgataaatc
    18661 atattttcca cacgcgcaac aaaggcttct ttagcaatag acggagccgt agcaatatag
    18721 accaggtccc catccttgat ttctacataa cgatggcgac caatcgacat cttacgaagt
    18781 ccattgatag gttcacccat acgacctgtc tcaagaataa tcaactcatg gtcttcaaag
    18841 cgagacatat ctttaggctt aatcaagaga atttcgttgg ctaaagacaa cttcttaaga
    18901 cgaatcgctg tgcggacgat attttcaata tcaaatcctg tcaagacgat acgtcgacct
    18961 gttttatccg cagcgtcaaa aatctgctga atacgagaaa gattactgga aacagctgca
    19021 acgatgatac gaccttccca gtcagcaata gtttgggtaa tttcatccct aacttcactt
    19081 tcactagcca cctgaatatt gctgtctgca ttggccgaat cactgaggag agccaggacg
    19141 ccgtcacgac caatctctgc caaacgagca aaatcagttg cataagattc actagccgtt
    19201 tggtcaaatt tgaagtcacc tgtataaacg atgcttcctt ccgatgtctt caagacaatt
    19261 cccagactct ctggaacgga gtaagtcgta gggaagaagg aaaccactgt cccaccaaaa
    19321 tcaatctccg tattctcatc aatgacatgg aaatcattaa atttcttaac ggcatcattt
    19381 cctttgacaa agagctttgc caactcaatg gtcaactcag acccaaatac aggaacttta
    19441 gcctctgcca agagataagg tagagcacca atggcatccg catgcccgtg ggtcaagaaa
    19501 accccagcaa tacggtcgct attttcaaaa aggtaatcca tgtttggaat caccacatcg
    19561 acccctaatt gttcattttc aggatatttt aaccctacat tcaaaacaaa aatggactct
    19621 ccaatttcag caatgtacat attttttcca ttctcacgca caccaccaag tgttgttaaa
    19681 ctgatattac tcatttttcc tccaaaatct tagtttatct tgattatagg gcaattctac
    19741 cctcttattc taaaagttct gatactttca gccgaatctt ttcctaccat tataccattt
    19801 ttttgatgat tttcaaaatg aaggtctgtt ttcaaaaaag agttgatttc ccaactcttt
    19861 cctaacttct actctttttc catcaaaaaa tcataaattt cttgcaccgt acccagcgcc
    19921 atcatttctt ggtctttaac ggtttgtttg agattttggt aaatttgact ttctcctatc
    19981 tcccgctttg gcgcctcttt attgactgtc atcacaccat cttttatcgt cacaaagcct
    20041 agttcttcaa atacttgaat catcttgacc agcaagattt gttgaatatt aagatatgca
    20101 gccaaatctt tcagcttgta gcgaatatca aactctggga actggtaaat agtcttgtac
    20161 aatttagcaa actgatctct agtcccataa cctgtcagat aataggtctt gtcaatatca
    20221 tttttgaaat agacagcaga gaaatgctgt tcctgaaaaa tggtcttcag ctgagtaata
    20281 tcctctggaa tgttttttac gacaacagct tcactagccg caagatttgg cagttctcca
    20341 ggaaaatcca agactggaac accttctggc aagactgcat tttttccacg aatgttaaaa
    20401 agttgaacac cttccactcg cgcatccacc atcatcaact ggagggcagt ttggccattc
    20461 cattggttga cagacaattt aaccgctaac tctagattct tggtttgaga aaactctgtc
    20521 gcccatctgc cttgaccaaa ggctaccact tcaaaactcg cctcaccctt ggaaattttc
    20581 agctttagat gggcattacc tgcccccata gtacgagcac tttcgacctg aaaattcttg
    20641 atataaaaaa taggtttctg attatccatt ccaaaaggag ctaaacgttc aaaacttttg
    20701 accgtttcca agctaagtgc ctccaaatcc aactcttcat ctaggtttaa cttattcttg
    20761 ccaccagcat ctgcaccttt ttcacgaaca taatcttcca aaacctgaga taaatctgag
    20821 agttgctcaa cttccagcgt catacccgct gcacctgcat gacctccaaa ggcgatgaag
    20881 aggtctcgat ggggatccag agcttcaaaa atatcgaccg cttccacact acgagcactg
    20941 cccttggcac gaccgtcttc tatattaaga acaatgactg tctgtcccaa ttcttccaat
    21001 aaacgaccag ccacgattcc tagaacccca ggattccagc cttccttggc caagacctga
    21061 accttcttct caggatccac catggtcttg gcttcttcat agatagactg aacgatttcc
    21121 ttgcgctctt cgtttttctg gtgaatcata agggcaatct catgcgcttc ctcatcatca
    21181 aatccagtca acaaatcaat ggcaggattg ggatcatcca agcgacccaa ggcattcaaa
    21241 cgaggagcaa tctggaaacc aaccgtttct tctgttactt cgttggcagc aatcccagcc
    21301 atgtccagca tttcttgcag accaatgcgc tgggtatgac ccaacatttc cagaccatat
    21361 tgaactaaga tacgattttc atccgtcaga ctcaccatat ctgcaatagt tccaatagcg
    21421 accaaatcaa gcaattccac ttgcacttct tctaacaggg cacaagccaa cttgaaagca
    21481 actccacaac cagccaaata tttaaaagga taatccgcat ctggatgttc aggatggaca
    21541 atagcataag catctggcag ggtttcaggc atggaatgat ggtctgtcac aatgacatct
    21601 actcccatag actgagccaa tgcaatagcc tcatgaccag caaccccatt gtccaccgtc
    21661 acaatcaagg aaattccttc ttgctcgata aagtatttat aaacactagc attagggcca
    21721 tagccatcgg taaaacgatt tggcaggtaa actcggcact cagcaccaag ttgttccaaa
    21781 ctttccttca caatagaagc cgaagtcatg ccatccgcat catagtctcc ataaacgaga
    21841 atattttccc cttcttcaat agcctgacga atccgctcca ctgccttgtc catatcatgg
    21901 agcagataag catcatgtaa gtcctccaag gaaggttcta aaaacttctt cagactttct
    21961 tggtcctgaa tccctctctc aaacaataac cgagccacct caggacccag tccagccttc
    22021 ttggctatct ttgtaaaatc cgcatcttct acctgcaggg caaactgcca ttcataagta
    22081 ggtgttatca aaaagacatc cactctttct aagaattcta ttgcttcatt ataacatgat
    22141 ttagacgttt tctctatcca gattgctttt ttataacatt ttatagtata ttgaaactag
    22201 aatagtacac ctctacttct aaaatattgt tagaaatcga tttgactgtc ccgatcgatt
    22261 tttcctgttc ttatttcact atagtgaatt ttttcagata tgatttgaca agaacattct
    22321 tttattgcag aatcgtgtta taaaatctaa cataaaggag ttctctcatg gttttagtag
    22381 aatttaaaaa cgtcgaaaaa tattacggag actaccacgc actccgcaac atcaatctcc
    22441 gttttgaaaa aggacaagtt gttgtcctgc ttggaccttc tggctctggg aagtccactc
    22501 ttatccgtac gatcaatggt ttagaggctg ttgacaaagg aagtctccta gtcaatgggc
    22561 accaagttgc tggtgccagc cagaaagatt tggtacctct tcgcaaggaa gtcggcatgg
    22621 tttttcaaca ttttaacctt tatccacaca aaacagtgtt agaaaacgtg acacttgcgc
    22681 ccattaaagt tctaggaatt gataaaaaag aagctgaaaa aaccgccaaa aaatatctgg
    22741 aatttgtaaa tatgtgggac aagaaagatt cctatcccgc catgctatct ggtggacaaa
    22801 aacagcggat cgccatcgct cgtggtcttg ctatgcatcc ggaactcctc ctctttgatg
    22861 aaccaacatc tgctcttgat cctgagacta tcggagatgt tctagcagtt atgcagaaac
    22921 tggcgcgtga taggatgaac atgatcatcg ttacccacga aatgggcttt gctcgagagg
    22981 ttgcggaccg cattatcttt atggccgacg gagaagtttt agtagatacg acagatgtcg
    23041 ataacttttt tgacaatcca agcgaacctc gtgcccaaca attcctcagc aaaattatca
    23101 accacgaaag tgacaaagtc aaataaggag gcgcctatga aaaaaaattc tttttatcag
    23161 cattattgat tagccttttc ggccttgctg ctgccaaacc agtccaggct gatacaagta
    23221 tcgcagacat tcaaaaaaga ggcgaactgg ttgtcggtgt caaacaagac gttcccaatt
    23281 ttggttacaa agatcccaag accggtactt attctggtat cgaaaccgac ttggccaaga
    23341 tggtagctga tgaactcaag gtcaagattc gctatgtgcc ggttacagca caaacccgcg
    23401 gcccccttct agacaatgaa caggtcgata tggatatcgc gacctttacc atcacggacg
    23461 aacgcaaaaa actctacaac tttaccagtc cctactacac agacgcttct ggatttttgg
    23521 tcaataaatc tgccaaaatc aaaaagattg aggacctaaa cggcaaaacc atcggagtcg
    23581 cccaaggttc tatcacccaa cgcctaatta ctgaactggg taaaaagaaa ggtctgaagt
    23641 ttaaattcgt cgaacttggt tcctacccag aattgattac ttccctgcac gctcatcgta
    23701 tcgatgcctt ttccgttgac cgctctattc tatctggcta cactaataaa cggacagcac
    23761 tactagatga tagtttcaag ccatctgact acggtattgt taccaagaaa tcaaatacag
    23821 agctcaacga ctatcttgat aacttggtta ctaaatggag caaggatggt agtttgcaga
    23881 aactttatga ccgttacaag ctcaaaccat ctagtcatac cgcagattaa ggaggatacc
    23941 ctatgacaga tttatcatct tggacagcct attttcagga ttttggacaa tttttcaatg
    24001 gtttcctctt tactcttgcc ctagcgattg gatcctttat cctcgccatg gtcttaggaa
    24061 tcttctttgg tgccatgtca accagtaaac gtccaatttt acgcatttta gctcgcatct
    24121 ttgtggaatt ttaccaaaat actcctctct tggtgcagtt tgttattgtt ttttatggcc
    24181 tacctcttat cagtgaccat atcatcatga ttccaattta ttggacagcc gttctctgcg
    24241 tgggactcta tcacggcgct tatatcgctg aggttattcg ttcagggatt cagtctattc
    24301 ctagtggtca gatggaggcc gccttgtcgc aaggttttac ctatatcagt gccatgcgct
    24361 tgattacctt gcctcaggcc ttccgcatca ttctccctcc attgaccaac caaattgtta
    24421 acctcatcaa gaacacctct actgtagcta tcatctctgg agtagacttg atgtttgtga
    24481 ctaagtcttg gtcggctctc aacggaaact atatcccagc ctttttaggt gctactcttc
    24541 tctactttgc cctatgcttc cctgttgccc agtttggtcg caagatggag caagccaaca
    24601 aaaaagccta ttcactttag gaggttacta tggaatctat tttagaagtt ttaaccccag
    24661 ataacctagt ctttatcttt aaaggatttg gcttgaccct ctatatttct ctgattgcca
    24721 tcatcctctc tactatcatc ggtacggtgc tagctgtcat gagaaatggc aaaaatcctg
    24781 tcttgcgaat catctccagc atttatatcg aatttgtgcg caacgttccc aaccttctct
    24841 ggatttttac tatctttttg gtgttcaaaa tgaaatccac accagcaggt attacagcct
    24901 ttactctctt tacatcagca gccttggctg agattattcg aggcggtctc aatgccgtag
    24961 acaagggaca atacgaagca ggaatgtcac aaggcttcac ctcagcccaa atcctctact
    25021 acatcattct cccacaagcc atccgcaaaa tgctaccagc catcatttct cagtttgtta
    25081 ccgtgattaa ggataccagc ctcctctact ctgttatcgc cctacaagaa ctctttggag
    25141 ccagccaaat tctcatgggc cgttatttcg aaccagagca ggtcttcagt ctttgcatcc
    25201 tgattgccct catctacttc agctttaacc tagcaatttc tagcctgtct catatgctag
    25261 ccaaacgttg gcaacaagct gcagaataat actcttcgaa aatctcttca aaccacgtta
    25321 gctctatctg caacctcaaa acagtgtttt gagcaacttg cggctagctt cctagtttgc
    25381 tctttgattt tcattgagta taaacagcca ctctccagtt caattggaga gttttttgat
    25441 gagagtagat atttatagac ctcaatttga caccatacat tttctatgat aaaatgtaac
    25501 aaatttattt acaacaaatc gaaatctaaa tgaaatggaa ttttctatga aatcagtcaa
    25561 aggactactc tttatcatag ctagttttat cttgactctt ttgacttgga tgaacacttc
    25621 tccccaattc atgattccag gactagcttt aacaagccta tctctgactt ttatcctagc
    25681 cactcgtctc ccactactag aaagctggtt tcacagtttg gagaaggtct acaccgtcca
    25741 caaattcaca gcctttctct caatcatcct actaatcttt cataacttta gtatgggcgg
    25801 tttgtggggc tctcgcttag ctgctcaatt tggcaatctt gccatctata tctttgccag
    25861 catcatcctt gtcgcctatt taggcaaata catccaatac gaagcttggc gatggattca
    25921 ccgcctggtt tacctagcct atattttagg actctttcac atctacatga taatgggcaa
    25981 tcgtctcctt acatttaatc ttctaagttt tcttgttggt agctatgccc ttttaggctt
    26041 actagctggt ttttatatca tttttctata tcaaaagatt tccttcccct atctagggaa
    26101 aattacccat ctcaaacgct taaatcacga tactagagaa attcaaatcc atcttagcag
    26161 acctttcaac tatcaatcag gacaatttgc ctttctaaag attttccaag aaggctttga
    26221 aagtgctccg catccctttt ctatctcagg aggtcatggt caaactcttt actttactgt
    26281 taaaaattca ggcgaccata ccaagaatat ctatgataat cttcaagccg gcagcaaagt
    26341 aaccctagac agagcttacg gacacatgat catagaagaa ggacgagaaa atcaggtttg
    26401 gattgctgga ggtattggga tcaccccctt catctcttac atccgtgaac atcctatttt
    26461 agataaacag gttcacttct actatagctt ccgtggagat gaaaatgcag tctacctaga
    26521 tttactccgt aactatgctc agaaaaatcc taattttgaa ctccatctaa tcgacagtac
    26581 aaaagacggc tatcttaatt ttgaacaaaa agaagtgccc gaacatgcaa ccgtctatat
    26641 gtgtggtcct atttctatga tgaaggcact tgccaaacag attaagaaac aaaatccaaa
    26701 aacagagctt atttacgaag gattcaagtt caaataagta atcatactct cctgggattt
    26761 cccaggagag ttttttatag ccaaatgaaa taagacagga acgatggaat tttggcattc
    26821 aaatcaattg ataagaatgt tttatagtgg agtgaaatag gatacgaaca aattgattag
    26881 gaaaatcaaa tgaatttata gaaatctttt agcagttatg ttgtcctatt ctagtttcaa
    26941 aacgctatag aagcagcatt gtgctagtct agattcagtt tactatacta aaacgagtag
    27001 cttgaaatca aaaaacccac cctcacaggc aggttttatc tgtattattc agctagatta
    27061 tgctttacct tctgaaccga atacgtcgat acgttcttca accgatgctt ggatagcttt
    27121 tacaccgtca gccaagaatt tacgtgggtc gaagagtttt ttcttgtcgt attctgcttc
    27181 gtttgcttcg tagtcacgag caaatttacg agttgcgtta gcgaatgcga tttggcattc
    27241 tgtgttaacg ttaactttgg caacaccaag tttgatagct gcttggattt gctcatcagg
    27301 aatacctgat ccaccgtgca atacgattgg gaatcctgga agagcttctg tcaatttttg
    27361 caagtggtca aggtctagac cttcccagtt tactgggtaa gggccgtgga tgttaccgat
    27421 accagctgcc aagaagtcga taccagtttc aaccattgct ttagcgtctt cgattggagc
    27481 caattcacct ttaccgatga ttccgtcttc ttcaccaccg atagtaccaa cttcagcttc
    27541 tactgagata cctttagcgt gtgctttttc aacaacttct ttagccaatt taaggttttc
    27601 ttcaactgga aggtgtgaac cgtcaaacat gattgaagta taaccaactt cgatacactc
    27661 aagtgcatct tcgtagtgac cgtggtcaag gtggatagct actggtacag tgatacccat
    27721 tgattcaaca aggttagcga tcaagttgcg agcaactttg taaccaccca tgtatttagc
    27781 agcacccatt gaagtttgga tcaaaactgg agctttttta gcttctgctg cgcgcaagat
    27841 agcttgagtc cactcaaggt tgtttgtgtt aaatccacca actgcataac cgttgtcacg
    27901 ggctgcttgg acaaattttt ctgctgaaac gattgccatt ttatcaggcc tcctgtatat
    27961 ttttatgggt catcccattt acattgttca ttttatcact ttttgccaaa aaaatctagt
    28021 ttttcccgca gtttcgattg attttcttct aactccatct atgtaaaccc tttctcccta
    28081 gtcttggacg acttttggaa aatctataaa gaaggttaaa cgattctcct ccatctcgaa
    28141 acgataagct aatttttcat gttctaatag actcttaacc acaaagagcc ccataccaga
    28201 ccccttgacc ttgcgactag cattgtcaga aaaagactgg gctagttttt cttgttcctc
    28261 tgagctacag ctattttcga taaaaagttc tccttctctt tctccaattc gaactaagcc
    28321 acctggaaca gagtgcttaa tggcattgct gatgagatta gaaagaatca acttcataac
    28381 tgatgggttt agataagcct gctgatgggt caaactattg tctatctgga gctctctttc
    28441 ctttgctagc aaggcataat ctttgaccag attttgcgtc atctggagga ggtcaattgt
    28501 ttccctatca tctcgcaatt cctgcacaga agagagggaa agtatctgca gaacatggtg
    28561 attgagttca tccacaatcc ccaaggcaac tcccagatac tggtctctat ccttataacg
    28621 accgatattc tctctcatat tttcgattag gattttcaaa ctagccagcg gtgttttcaa
    28681 ttcatgagaa gctcctcgta ggaattcgac cttcatcttc tccagctgga gaatggcttc
    28741 attcttttca tgcaagtccg caataacagt caagagatgc tggtagaggc tattgatttg
    28801 ttccttgaga ttacctatct catccttaga atccacgcgc aatcgcactt gggaatccag
    28861 gtccatcatc cgacgggtca cccgcttgat ttccaaaatc ggtgcaacaa tagtccgagc
    28921 gtagatgtag gccaccaaga gggaaatcag aaaggaggcc agcaaggtat agggaagaaa
    28981 ctggagactg atttgctccg cttccttttg taaatccatg gaagctagaa actggagaat
    29041 catagtacca ccgtcttgcg ttttcacctc gcgctcctca ataaagagag aggttgtctg
    29101 gcggtctgtg tccagaggaa gactgtcctt gacttctaac ttgtcctcgg tcatctcacc
    29161 tttgacggtc cccttgatat cactagtctg ggaatacaag tctaacactt gctcgatact
    29221 ctgcctatct ttcccttcta gggactgggc aatggctgtt gccttttgac caatggtttc
    29281 ctgacgatga ctcagataag tcgaaggaaa aagaaaataa atagctaaat gaaggcagat
    29341 aaccagaaca ctaaatatcg agaaggtata gataaatatc tttgcaaata aacctgttcg
    29401 tttcattttc gctccaattt ataaccaaca ttgcgcacag tgaggataca atccaagtct
    29461 agctttttcc gcaattcctt gatataaaca tcaataacac ggtcaaaggg aacctcatct
    29521 gtcgctttcc agacggcatc gataatctga gatcgagtca aggcccggcc ttcatttttc
    29581 actagatagt ccagaatttc caactctttg gcattgatag gcacttcttg acctgcgagg
    29641 cttgcactgt agctttcaaa gtccaccttg gtatccttgt aagaaaagat tcgtcctgta
    29701 tcgtagtagc gcttgaaaat cgcgtccacc ctcactttta aaagggagag ggagaaaggt
    29761 ttttccagat agccatctgc caaagaggca aaggcactca tcttgtattc ctcatcttga
    29821 aaagctgtca acatcaagac aggaacctga ctggttttac gaatctcagc taggacttct
    29881 aagccgttga gcttgggcat ctggatatcc agtaaaacca gggccacctc atagctagaa
    29941 aattgctcca gagcttcctg accgtccgct gcctcaatag tttcatagcc acaatccgtc
    30001 aaataatcac tgaccccctc acggatcatc tcttcatctt ctacaattaa aattttcata
    30061 ctttaactgc tctctatttt ttatttttct tagaataaat acctacccta ttttctatta
    30121 tagtctcttg ctggcctttt gtctgcaagc aactgaccac tagataaaac gttgtgaaat
    30181 tcctttctca taaattccat aactttagta tattatattt aagcactaaa gtacaaagaa
    30241 agcaactgaa agcaatgatt ttcaccactg ctttcggatt tattttgaat tgttaaatag
    30301 ccattcctat ccactattct tgaatagaaa cacaagatgc aatctttatt ctagactcat
    30361 tttttcaaat ttattcacca tccagcaaga gctcttttgg ttgttttcta aggagattgc
    30421 ttgaagcaag cgccataacg agaaccacta gaaccaaggc aaggacaaaa atgatgataa
    30481 agtctgatgt ctgaatggaa atgtctaggc tcgacaaggt cttgctaaag ccatctactt
    30541 ctgcaccacc accaaggtta gaggcttgag ccgccttact agcctgtttg gcaacacctg
    30601 aagtcacatt ggcaaggaca gtgtttccaa ttgcacgggc agtgtaatta gctaggaagt
    30661 aagcagaaac tagagcaggg atagcaatca agatagattc ggtgatgaat tgacccaaga
    30721 tacttgcctg cttgaggccg atagagagga gaattcccac ttccttgcga cgggcgttga
    30781 tccaaaggct gagcaagagg gcaaggagga gaactgagaa gctcaagcta ccccagaaga
    30841 ggaggttggc catcttgtac ataccagaga tagattgctc aagagctggg tagttagagg
    30901 agctcttgac gagtgtgtag ctcttccagt tgataccact gatgccattc aactctttca
    30961 taacatcatc caagttcttg tctgctgtta caaagaaggt tgcgtcccca taaatggctg
    31021 tgtcttctgt gtatccataa agttttgcag cagtgtgaat gtctgtaata gctgtgtttt
    31081 cgtaaagttc ttgtgagtag gttactgctg acttattatg accatcaaag agtcccttga
    31141 ttgtcacttc aactgtttcc ttggctcctt tttcattatc tgcatcgtag atattagagt
    31201 ccagtttaac cttgtcccct actttccagc cgtgtttggc tgccaagtcc ttgtgcaaga
    31261 ggattttatc cttgtcgtcg ttggttaagt gctctccttc gactagttta taagaaccag
    31321 agacaaactt gtcttcttta gaggagtcat tgacacctgt aatcatcaag ctacttccaa
    31381 aacgcttggc acgatcagca gtgagattct tcttggtttc tggcgtttca atcaggtcat
    31441 atccagtcaa atctccgata gcgttgatac gtttgacata agactcaatg gccttgtttt
    31501 cggtgatttt tttgatgtct tcacccttga tattcccagc accacgaggc gttccttggt
    31561 tgacgcgacg attgatttgc atggagaagc tattggtgat atttttaaag gtctcctgag
    31621 aagccttggc agtagctccc ttgattgaca agccgaccaa actcaagctc gccatgagga
    31681 gaataatcag gaagatgaca atcgatttga aaaacttcct tgtaacatag gcaaatgcgt
    31741 tgtgtaacat agattccctt tctagatttt gttttaatca ttctattaaa ataagctcaa
    31801 attatttact agtattgcgc gtttcagtca gtttcttatc ctttaattca agtgtaatat
    31861 ctgacgcttg tgccacttct ttactgtgag ttacgacaat cacacattta cctgttttct
    31921 gggcaagtga tttgagtagt tcgacaatat ctccagcagt tttaggatcc agatttcctg
    31981 ttggctcatc agctagaata actggagctt ctgagaccaa actgcgagca atggcaacac
    32041 gttgctgttg accacctgat aactggagaa cattccgctt gatctggctt tcatccaaac
    32101 caagctcaag aagtgtattc ttgcttgcct ttttgttgac caatcggata ttttccagcg
    32161 gagaaagata atctatcaag ttataatttt gaaagaccag ggaaatatgg tgcatgcgat
    32221 ggtaagaata gcccttctta cgaatatcct ctccttgaaa aaggatagaa ccttcaacag
    32281 gactatctag accagcaagt agggacaaga gtgtggattt tcctgctcct gactccccaa
    32341 taatactgta aaattttccg ggttcaaaat tataattgat ctgatatagg actgcttcag
    32401 cagtattctt ataacggtag gtaacatctt gtaattgtaa taaagtcatg atttctcctt
    32461 cttaactaat agatgataaa atttctttcg gtgattttct aaataagaat aggaaacaaa
    32521 gggctacaga taagcaacta agcagaacta gaaaaacata ggattctgca aaagataaga
    32581 tgctagttga taaactgctt gctttggcta gtgtatcttg taagcttgcc tgatctccac
    32641 ttgctagtag agtttggagt aggtaagttg tgattgcgtt tcctgcaaca aatgctggaa
    32701 gcaaagctcc aagagatacc aaaactacct ctaaacagaa ttgtaggaag atcgagctct
    32761 tgccttttcc aagtgcaagt aaaatcccca cttcatagac ccgttctctc aaccagagag
    32821 acaaaaccag aattaaggct ccagctcctg ctatcaacat cccataaagg aagatggtca
    32881 ggaaggtttg gaaagttgca actgagtctt tgatttgttc aaaagccttg ttttcctttt
    32941 cgacttggta gccttgattt tccaaggcca agttttctac ctgcttcatg agtccgtcca
    33001 tttccttagg attttctaca tagaagcgtg ctgcactgac ttgagcttca ctattgccca
    33061 aaagggtttg gctactttca tagtctgtaa agacttgatt ttcactgaag tcagaagaca
    33121 agcctgtgaa tttctcttgt tttttaccag aaaagatgcc gataatctca aactctactg
    33181 tttgtccttt tccagattca gactgaccag catccaagcc aatcttgtca tgaagcgaaa
    33241 gaccgttctt cttagccaat tcttcgtgga taaggatttt cttggaatcc cctttttgaa
    33301 ggtgtcgccc ttcttttaga ttgaaagccg aactggtaaa ggttacatcc ttggatgaat
    33361 cctcaagagc cgttaagcta accaagttat tgtctgcagc tgataaatca tcacgctcca
    33421 cgctctgctc gccagtcact gcttccttgt cttttagttt tgcgaccgtc tcaagttcag
    33481 gagagacatt ttccagcccc ttaatcttgc ttacagatgc taggtctgac aacttgaatg
    33541 tctgaccatt ctctatcttc ttaatagaaa aagatgtatt gagtgattta taaagattgc
    33601 tttctactgt tttgttggac ttcatcagag tcaaacaggc tgaaattccg gccaataaga
    33661 ccaataaaat cagaaataaa ataaaacttc tcagtcgctt tctgctgaca taagcccaag
    33721 atctttggat tggattcatt tgtcacctcc atatttgtaa gactattata aaacccaaat
    33781 atgaaatgtt tatgaaatac gaaaaaaaaa tatcgagtag gggataatct ctagcccctc
    33841 tcacaccacc atacgtgccg ttcggcatac ggcggttcaa ctaact
//
LOCUS       DAVKMJ010000028        32347 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000028 DAVKMJ010000000
VERSION     DAVKMJ010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.028"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(28..513)
                     /locus_tag="VW348_001324"
                     /pseudo
     CDS             complement(28..513)
                     /locus_tag="VW348_001324"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            complement(546..884)
                     /locus_tag="VW348_001325"
     CDS             complement(546..884)
                     /locus_tag="VW348_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9746218.1"
                     /translation="MKNYGEAFRYFRKLNGYSLEYAAADFISKSQLSRFERGENEISL
                     STFFELLSNINVSIENFCNHLEYYKRSERDDFLVNLSPNFYSLNIKGLEVIKNKQQKL
                     FEKSGKKLIK"
     gene            complement(897..1670)
                     /locus_tag="VW348_001326"
     CDS             complement(897..1670)
                     /locus_tag="VW348_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9746219.1"
                     /translation="MIDKVIEQYKSHDNLDIRVELHKKYSKNKLGFNNWIFSNYQITD
                     EVKVLELGCGTGELWKSNSDSIDKMKQLIVTDFSKDMVKSTKSVIGNRNNVNYEIMDI
                     QKISFENETFDIVIANMLLHHVNDIPKALSEVNRVLKTGGIFYCATFGENGVVNYLAS
                     LFKDEVNQDLENRTFTLQNGKRYLSRYFNSVDTLLYDDELQVTSIDDLVKYIQSFKGI
                     SEIGSLEEEIIRKRLESEFNNGMLIIPKEYGMFIARKES"
     gene            complement(2116..2871)
                     /locus_tag="VW348_001327"
                     /pseudo
     CDS             complement(2116..2871)
                     /locus_tag="VW348_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(3009..4631)
                     /gene="groL"
                     /locus_tag="VW348_001328"
     CDS             complement(3009..4631)
                     /gene="groL"
                     /locus_tag="VW348_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEU9746220.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(4647..4931)
                     /gene="groES"
                     /locus_tag="VW348_001329"
     CDS             complement(4647..4931)
                     /gene="groES"
                     /locus_tag="VW348_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEU9746221.1"
                     /translation="MLKPLGDRVVLKVEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(5201..5596)
                     /locus_tag="VW348_001330"
     CDS             complement(5201..5596)
                     /locus_tag="VW348_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEU9746222.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(5674..6435)
                     /locus_tag="VW348_001331"
     CDS             complement(5674..6435)
                     /locus_tag="VW348_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEU9746223.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(6468..7094)
                     /locus_tag="VW348_001332"
     CDS             complement(6468..7094)
                     /locus_tag="VW348_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEU9746224.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLDVERKGKVARVFLKDNGE
                     TVAWNIFEVSSLFEIAERGQVFLTDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKTVQIVAGAPNARVGLKTIVALPGAMMPKGNLIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(7110..7427)
                     /locus_tag="VW348_001333"
     CDS             complement(7110..7427)
                     /locus_tag="VW348_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEU9746225.1"
                     /translation="MIQPASLEELASLVEKDGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRVDRDQYIDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLA
                     GLK"
     gene            complement(7424..7723)
                     /locus_tag="VW348_001334"
     CDS             complement(7424..7723)
                     /locus_tag="VW348_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEU9746226.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDHKLMKTQEELTA
                     IVRDHFSDMGEIATLYVQVYESSLESLLGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(7973..8161)
                     /locus_tag="VW348_001335"
     CDS             complement(7973..8161)
                     /locus_tag="VW348_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
                     /protein_id="HEU9746227.1"
                     /translation="MKASTWVYDKGEWYYVSSSGAMLANDWVKDNGKWYYLASSGKML
                     RNTYTPDGYYVGNSGAWQ"
     gene            complement(8412..9086)
                     /locus_tag="VW348_001336"
     CDS             complement(8412..9086)
                     /locus_tag="VW348_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746228.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     ELVYVK"
     gene            complement(9092..9538)
                     /locus_tag="VW348_001337"
     CDS             complement(9092..9538)
                     /locus_tag="VW348_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9746229.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(9652..10155)
                     /locus_tag="VW348_001338"
     CDS             complement(9652..10155)
                     /locus_tag="VW348_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU9746230.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            complement(10152..10514)
                     /locus_tag="VW348_001339"
     CDS             complement(10152..10514)
                     /locus_tag="VW348_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HEU9746231.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFLQAPYYVPERIAITGKICGVHIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(10580..12439)
                     /locus_tag="VW348_001340"
                     /pseudo
     CDS             complement(10580..12439)
                     /locus_tag="VW348_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(12478..12927)
                     /locus_tag="VW348_001341"
     CDS             complement(12478..12927)
                     /locus_tag="VW348_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEU9746232.1"
                     /translation="MGKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIDQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQAKYQGNRRRE"
     gene            complement(13051..13767)
                     /locus_tag="VW348_001342"
     CDS             complement(13051..13767)
                     /locus_tag="VW348_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9746233.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(14648..16063)
                     /gene="ply"
                     /locus_tag="VW348_001343"
     CDS             complement(14648..16063)
                     /gene="ply"
                     /locus_tag="VW348_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEU9746234.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLVSSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            complement(16074..16406)
                     /locus_tag="VW348_001344"
     CDS             complement(16074..16406)
                     /locus_tag="VW348_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746235.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(16477..17085)
                     /locus_tag="VW348_001345"
     CDS             complement(16477..17085)
                     /locus_tag="VW348_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746236.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(17098..17556)
                     /locus_tag="VW348_001346"
     CDS             complement(17098..17556)
                     /locus_tag="VW348_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEU9746237.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            17681..18080
                     /locus_tag="VW348_001347"
                     /pseudo
     CDS             17681..18080
                     /locus_tag="VW348_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(18845..19105)
                     /locus_tag="VW348_001348"
     CDS             complement(18845..19105)
                     /locus_tag="VW348_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746238.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFFDG"
     gene            complement(19164..19715)
                     /locus_tag="VW348_001349"
     CDS             complement(19164..19715)
                     /locus_tag="VW348_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746239.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNSEFPSMIELFSIL
                     PEYPLKKDGREIPLYFDQDASLSALLLDEDYYNILVHVKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(19705..19902)
                     /locus_tag="VW348_001350"
     CDS             complement(19705..19902)
                     /locus_tag="VW348_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746240.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(19906..20700)
                     /locus_tag="VW348_001351"
     CDS             complement(19906..20700)
                     /locus_tag="VW348_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746241.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENISYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(21108..21533)
                     /locus_tag="VW348_001352"
     CDS             complement(21108..21533)
                     /locus_tag="VW348_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746242.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDNNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(21662..22045)
                     /locus_tag="VW348_001353"
     CDS             complement(21662..22045)
                     /locus_tag="VW348_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746243.1"
                     /translation="MYHLYYDEVKKSSVSLILIGEGDETERKADQLASYFLIFPSSLY
                     RMVEEIRENANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIE
                     TASRLGYDTSLYRPLSESKKEMVLG"
     gene            complement(22067..22273)
                     /locus_tag="VW348_001354"
     CDS             complement(22067..22273)
                     /locus_tag="VW348_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746244.1"
                     /translation="MDLSNKASNLRKKLGADGEAPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMSLGR"
     gene            complement(22260..22433)
                     /locus_tag="VW348_001355"
     CDS             complement(22260..22433)
                     /locus_tag="VW348_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9746245.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLYLSLNQSMIAK
                     MEKGERNITNGFK"
     gene            complement(22792..23748)
                     /gene="lytA"
                     /locus_tag="VW348_001356"
     CDS             complement(22792..23748)
                     /gene="lytA"
                     /locus_tag="VW348_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEU9746246.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADRPEFTVEPDGLITVK"
     gene            complement(24124..25494)
                     /locus_tag="VW348_001357"
     CDS             complement(24124..25494)
                     /locus_tag="VW348_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEU9746247.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSTFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            complement(25808..26974)
                     /gene="recA"
                     /locus_tag="VW348_001358"
     CDS             complement(25808..26974)
                     /gene="recA"
                     /locus_tag="VW348_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEU9746248.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(27029..28285)
                     /locus_tag="VW348_001359"
     CDS             complement(27029..28285)
                     /locus_tag="VW348_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEU9746249.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFEGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(28370..29386)
                     /locus_tag="VW348_001360"
     CDS             complement(28370..29386)
                     /locus_tag="VW348_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEU9746250.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(29394..29912)
                     /locus_tag="VW348_001361"
     CDS             complement(29394..29912)
                     /locus_tag="VW348_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9746251.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(29902..30345)
                     /gene="tsaE"
                     /locus_tag="VW348_001362"
     CDS             complement(29902..30345)
                     /gene="tsaE"
                     /locus_tag="VW348_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEU9746252.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(30431..31051)
                     /locus_tag="VW348_001363"
     CDS             complement(30431..31051)
                     /locus_tag="VW348_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746253.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(31434..32297)
                     /locus_tag="VW348_001364"
     CDS             complement(31434..32297)
                     /locus_tag="VW348_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9746254.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEVKSNLSNFKHLSARLLDDRNYDDLEYLYKIEVERS
                     TFLTLEDRTYLEWIKSIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
BASE COUNT         9765 a         7084 c         5430 g        10068 t
ORIGIN      
        1 acaatatctt aacagagaaa atgatattta atctatcagc tcatttaatc gtttttgaaa
       61 atataaagca atacttttag attcaataaa ctcaaaatat tttatgacat tgtccatttg
      121 tttaattcca gattctttag attctgtcag gtatatttta tatccttcta caaatttgaa
      181 tgtagatttt tcaaaaactt ttgtgtcatc ttttaataat ttttgtaatt tcatttcaaa
      241 gtagtctgca tatattagat gtgaattttc aaggcaacag aaccaaaaat ttaaacaagc
      301 tgacacaact aaatttctat tcttgccgat tttttcgtaa taatgtgtac gctctagtat
      361 ttcttttccg accatgtaaa tataatctat ttcaaaaaga tgatataaat taccaatcag
      421 cgttatctca taggactccc atcgttcctt ctggaataaa tagtcatata ctaaatttag
      481 atcatctcta ctaactacat gattacaatc tagctgattt cataatccct gaaccataat
      541 tgtatttatt ttatgagttt tttcccactc ttctcaaaaa gtttttgttg cttatttttt
      601 attacctcca atcctttaat attcaaacta taaaaatttg gagataaatt aaccaaaaaa
      661 tcatcacgct ccgatctttt ataatattct aagtgattac aaaaattctc tatcgaaaca
      721 ttgatatttg ataataattc aaaaaatgtt gaaagagaaa tttcattttc tcccctttca
      781 aatctagaaa gttgagattt tgatataaaa tcagctgcag catactctaa agaatatccg
      841 tttaattttc taaaatatcg aaaagcttct ccgtaatttt tcacactttc attcccttaa
      901 ctttcttttc gagcgataaa cataccatat tctttaggaa tgatcaacat accattatta
      961 aactcacttt ccaatctttt acgtattatt tcctcttcta gtgaacctat ttctgaaatt
     1021 cctttaaacg attggatgta tttaactagg tcatctatac tagttacctg taactcatca
     1081 tcatagagta atgtatcgac agagttaaaa tacctactca ggtacctttt accattttgt
     1141 aaagtaaacg ttctattttc taaatcttga ttaacctcat ctttaaataa acttgccaaa
     1201 taatttacaa ctccattttc accaaatgta gcacagtaaa aaatgcctcc ggtttttaag
     1261 accctattca cctcagagag agctttagga atatcattca catgatgtag aagcatatta
     1321 gcaataacaa tatcaaaagt ttcattctca aaagaaatct tttgaatatc cattatctca
     1381 taattgacat tgtttctatt tccaatcact gacttcgttg attttaccat atctttagaa
     1441 aaatctgtaa caatcaactg cttcatttta tctatagaat cactattact tttccacaat
     1501 tctcctgtac cacatcccaa ttctagaacc tttacttcat cagtgatttg gtagttagaa
     1561 aatatccaat tattaaatcc caatttattt tttgaatact tcttatgcaa ttctactcga
     1621 atatcaagat tatcatgact tttatattgt tcaattactt tatcaatcat tttaaatgac
     1681 ctccactcta taatttggca ttatatcaca agaataaaga tagtgttaaa taagttatat
     1741 aaatgcaaaa aaggaatatt ccgttatagc agagttgtaa cacatttcta taaagaaatt
     1801 tattcctacg actcagtttg gcatgcttaa cttcctaact caaaaacaaa gcatcgatta
     1861 atttatccgt tcttcttttg aaacagattt gaactgataa ttgctcgttt taatttaaaa
     1921 agctcttttg agcaaaactt cattttttta agagtccaac aatttctgtc tatcgctttt
     1981 ctactagcaa aaaacctacc ttgaggcaag ttttcattta tatatctaat ttcgtaacag
     2041 tatagtaaaa tgaaataagg acagtcaaat cgatttctaa caatgtttta gaagtaaagg
     2101 tgtactattc tagtttcaat ctactataaa tttgatatga gaatagtctt tctcaacatc
     2161 cttatccaac aagcatgctg tggcgtcctt cttaacttaa accaggtcaa tattctgggc
     2221 ttgggctgca tagacgcagc cacaataaca ttgacgatag atatcatact cctcacacat
     2281 ctctactgaa cgtttgtagc cttgattttt cttgaaatcg ttgggaagat agtggggcgt
     2341 gtaaattttt tgcacatcga ttccgatgct attgatagtt tgagaattct tatgaggact
     2401 gatggtcaag gctgaaccaa agtagtcaaa gcccaagtcc atagccactt gcgctgtttt
     2461 atccagtcgg tagtcaaaac aaaccttgca acggtcgcca ccttcgggct cctcctctag
     2521 ccccctaact agttttcggt attaattggg ttcgtaggga gcttctaggt actgaaccgt
     2581 atttcctgtc cgctcattaa aatcactaac aaatttcttg gtgacataga cccgcttatg
     2641 gtattctgcc ttgggatgga tattagaatt ggcaaaatag atggtcacat ctgcatactt
     2701 ggtcaaatat tctagtgtat aggtactaca aggggcacag caaacatgca cgagaatggt
     2761 tggccgctac tcattttttt cccatgcttg taccattttc tgcatgacac ggtcataatt
     2821 aatcttctga ttgggggtca tcttgcacag aatttcttct acatcgatca tgttcttctc
     2881 ctttttctag tcttatttta tcatataagt taggagagct caaatcaatt tagaagtgaa
     2941 tattataaaa agaagggtta gtcattccct ccttttgtgt tttttataag ttgttttcta
     3001 tagaaagctt acatcatccc gcccatcata cttggatcca ttgctggagc tggggctact
     3061 ggttctggtt tattggctac gactgcttct gttgtcaaaa tcaagctggc tacagatgct
     3121 gcattttgta gggctgaacg actcacttta actggatcaa tgataccttg atcaatcatg
     3181 ttaacccact cgccagttgc tgcgttgaat cctataccaa gctcagcatt tttcaaacga
     3241 tcgataacga tagatccttc aaatcctgca ttgtgagcaa tttgacgaac aggttcttcc
     3301 aaagcacgga gaacaatatt acgtcctgtt gcttcatctc ctgtcaattc caaggtagca
     3361 acagctggaa tcacattggc aagagctgtt ccaccacctg caacaatacc ttcttcaaca
     3421 gctgcacgag tagcgttgag ggcatcttca atgcggagtt tcatttcttt caactcagtt
     3481 tcagttgcgg ctccgacctt aataaccgct acaccacctg acaatttggc caagcgttct
     3541 tgcaattttt cacggtcaaa ttcagaagtt gtagtttcga tttgagactt gataaccgca
     3601 acacggtgag aaatcgcttc aggatttcct gcaccttcta caataaccgt gctatctttg
     3661 tccacggtca ctctcgctgc ttgaccaaga gcttcaattg tcgcatcttt caactcaaga
     3721 ccaaggtctt ctgtgataac tgttccgcct gttaagatgg cgatatcttc aagcatggct
     3781 ttgcgacggt caccaaaacc aggtgccttg actgctacta cgttgaaggt tccacgaatc
     3841 ttgttcaaaa caagagttgg aagagcctcg ccatccacat catccgcaat aatcaagagt
     3901 ggacgattgc tttggagaat gctttccaaa agtggcaaga tttcttggat attggaaatt
     3961 ttcttgtctg taatcaaaat gtacggattt tcaaggtcag ccaccatttt ttcgctatct
     4021 gtcaccatgt actgtgaaag gtaaccacgg tcaaactgca ttccttctac gacttcaagc
     4081 tctgtttcca taccacgtga ctcttcgatg gtgatgacac cgtctttgcc aactttttcc
     4141 attgcttcag agatgtactc accaactttt tcagaacgag aagatacggc tgcaacttga
     4201 gcgatagctt ctttattggc aacagggatg gcgttgtttt tcaaagcttc aactgctgcg
     4261 gcaactgctg tttcaatccc acgacgaata ccgattggat ttgcacctgc tgtgacgttt
     4321 ttgattcctt cacggacgat tgcttgggtc aaaacagttg cagttgtagt tccatcacct
     4381 gcgatatcat tggtttttga agctacttct gataccaatt tggcacccat attttcaaaa
     4441 tggtcttcta attcaatttc tttggcaata gtcacaccgt cattggtaat caatggtgag
     4501 ccaaatgatt tttcaagaac gacattgcga ccttttggtc ccaaagttac tttaacagta
     4561 tctgcaagga tatcgacacc acggaccatg gctgaacggg catctgatga aaatttaatt
     4621 tcttttgaca tacttacttt ctccttctat tcttcaatga ttgccaagat gttagcttcg
     4681 cctacgatga tgtacttttc atcgccatct ttgacatcaa gacctgcgtg ggcttcaact
     4741 aagacacggt ctccagtttt aacacttgga gcaaccaagt caccgttcaa ggtacgaaca
     4801 ccttgtccag tagccacaac ttgggctgtt ttggtttttt cttgggctga acctgcgaga
     4861 acaaagcctc caacagtttg ttctttttct tctactttta agaccacacg gtcccctaat
     4921 ggtttcaaca tctgatttcc tccataatga gatagatatt attagcactc tttatacctg
     4981 agtgctaatt catagttcta ttgtatcact tagtcagaaa taatcaagaa aaaagtctga
     5041 ctttctcaag ataaaaagcc tgagaccaac tcagactttt taatgtttat actcaatgaa
     5101 aatcaaagat caaactagga agctagccgc aggctgctca aagcattgct ttgatgttgt
     5161 ggataaagct aacgtggttt gaagagattt tcgaagagta ttaaaatggc aattcttcct
     5221 cttccaagac taaatctgcc aaatcttggc ctgcattatt ttcacgcatg gcacgttgag
     5281 cacgactttc caagagttgg aatcctgtta caagtacttc ggtcacgtag ttcatttggc
     5341 catttttctc aaagcgacgg gtacgcaatt ctccatcaac ggaaatgaga ctacctttgg
     5401 ttgcgtagct tgccaaagtt tctgctagtc tgccccatag gaccatattg acaaaatcag
     5461 cttcacgttc accgttttgg tctttgtaac gacggttgac agcgatagtt gctcgcgcta
     5521 ccgacttgtc attgttggtt ttgtgcaatt ctggtgtaga cgttaaacgc ccaatcatga
     5581 taactttatt atacatattt tcttcctcct acttatctat tcgtaggaaa tcaaaaaaag
     5641 ttacagaaat ttgtaacttt tcgaggaaat ttcttatttt ttatgaatca tgaaacctgt
     5701 cgcctgttga ttggccataa tggtcatatc tgtaatctga acacggcgag gctgactggt
     5761 cacatagact actgtgtctg caatatcctg agcttgcaag gcttctattc cttggtaaac
     5821 ggacgcagct cgctctttat caccatgaaa acgaacagtt gagaaatctg tttcgacaat
     5881 cccaggctga atggttgtca ccttgatatc cgttgcgatg gtatcaattc gcagtccatc
     5941 cgaaaaggtc ttaaccgcag ccttggtagc tgagtaaaca gcggcaccag cataggcgta
     6001 gattcctgcg gttgacccca tattgataat atgaccttga ttgactttta tcattgctgg
     6061 caagaaacag cgagtaaccg ccatcagacc tttaacattg gtatccaaca tggtcaacat
     6121 atccaactcc tcatagtctt gatagggagc caagtcaaga gccagtccgg cgttgttgac
     6181 caagatatca atcctcccta tcgtttctag aatatcagag caaacagtct tcaccatgac
     6241 catatccgtc acatctagtg gaaaagtcca gacggtttga tttggaaagc ttactgcaaa
     6301 ctccgacttg aggatttcta atctgtctat ccgtcgtcct gttagaacga catcctcacc
     6361 ctgctccaga taagcacgcg caatcgcttc accgattcct gaggttgctc ctgtaatcac
     6421 tacatttttt gccatcttat ttccttctat cagatgctga caagttccta ggcagtccag
     6481 tgtttcgctg ggtcgaacgg tgttccgaca acttggtctt ctgataattc aagcacccca
     6541 cgtttttgtg gagcatttgg cagatgcaat tcacgaggac tgcacatcat accaaaactc
     6601 ttttcaccac gaagttcacc tgggaaaatg agattccctt ttggcatcat agctccagga
     6661 agcgcgacaa tggttttcaa ccccacacgc gcattgggag ctcctgcaac gatttgtaca
     6721 gtcttatcac ttgcgactgc aacttggcag atgttgaggt ggtcactatc tggatgggct
     6781 accatctcaa caatttcacc gacaacaaac ttaggttcct tatcattaac aatttcttct
     6841 gtaaaacctt ccgcctgcaa ctcttggttc aaacgagcga cttgctcatc tgtcaaaaag
     6901 acttgaccgc gctctgcaat ttcaaataaa cttgaaactt cgaaaatatt ccaagccact
     6961 gtttccccat tatctttgag aaaaacacgg gctaccttgc ctttgcgctc cacatccagt
     7021 ttggcatctc cgctattttt cacgatgacc ataaggacat caccgacatg ttctttatta
     7081 tatgtaaaaa tcattgtttc ctttttctcc tatttcagtc ctgctaaaaa gtcattgatt
     7141 tgttgcttgc ttttacggtc gcgattgaca aaacgaccga tttccttgtc cttttctaga
     7201 acaacaaggc tagggattcc atatacatcc cagagtttgg ccaaatctat atactggtct
     7261 ctatccactc gaataaaggt aaactctgga ttagtctcct caatttctgg taaggcagga
     7321 tagatataac ggcaatcgcc acaccagtcc gccacaaaaa ggaagacctt cttaccgtct
     7381 ttttctacta aagatgccaa ttcttctaaa cttgctggtt gtatcataag acttcctcct
     7441 catagactag gtcttcattt tcatagacaa aagtataatg acggccatcc tcaaaaatga
     7501 cgccaccaag caagctctct agactgcttt catagacttg aacatagagg gtcgcaattt
     7561 cccccatgtc tgaaaaatgg tctcgtacaa tcgctgtcaa ctcttcctga gtcttcatga
     7621 gcttatggtc atctgcaact tttttcgtag caagggcaag gctcccaata ccaagcagag
     7681 ccagacctgc catccacatt tttttagctt tcataccatt cattttaaca caaaaaaggc
     7741 tttaggacaa atgaggaaac agcaaaaaag caagtaaaaa gcctcttcct ttaaggaaaa
     7801 ggacttctta tactcaatga aaatcaaaga ccaaactagg aagctagccg caggctgctc
     7861 aaagcactgc tttgaggttg tagatagaac tgacgaagtc agctcaaaac actgttttga
     7921 ggttgtggat gaagctgacg tggtttgaag agattttcga agagtattat tcttattgcc
     7981 aggcgcctga gttaccaacg tagtaaccat caggtgtgta ggtattgcga agcatcttac
     8041 ctgatgaagc tagataatac cacttgccat tatctttgac ccaatcattc gctagcatgg
     8101 ctccagaaga acttacataa taccattctc ccttgtcata aacccaagtg cttgctttca
     8161 tggctcctga gcaattaaag gttcaaaaaa ctgtccaata tcattcattt ttttaaagca
     8221 ttttacacta catcatccac gctgtaggac atagatacat caaacgtaag agccaaaata
     8281 tcgaaaaata tacaactttt aaaggcaaca tttcattttt taaagtctaa caaccataga
     8341 actgaaatca gagcaaggca tcaacttcct actcttagta cgtctatttt gatggttgaa
     8401 gtgaagattt tttatttaac gtagacaagc tccaacttcc caaaagccac atctccacgg
     8461 ataatcaagg ttttgctggt tggggctaca ggagcgtcag ccttagctgc accaaaggag
     8521 gtttctactt tcaaatctac acgccagtgt tgtggaacat agacggttgc attcccgaag
     8581 gccacttcaa tatttaaagt tgcaaaatca cctagcatct ctgcattatc atagtagatt
     8641 ttagcatccc caaaagcgac ttccacttgg tcatctacga gatcttgatc ttgcttatag
     8701 aaggtcccgc taccaaaagc gacttcctta tccgtgacga ctgttttttt cccattgtac
     8761 caccattttt tttcattcca gaacttactt gaatgcgtca gataaccaac accaagtacc
     8821 accaagatgc tagcccaaat aagagaatga ttggtaactg gtaacaagtc ataagcgtaa
     8881 tttgcaatga tgagcgccag taaacctgta aaaactgccg aagtgagatg acgtctaagg
     8941 atggactcaa tggacttata agcaaaaaaa acaataccta gtaaaggcca tattttacca
     9001 tccaaagaag gaattccaaa attcccttgc agcaagatcc aagctgctaa aaccaataaa
     9061 acaataccaa atgctttctt tttcatgttt tttacctcat gtttcttaga ttttctttta
     9121 ggagggattg gtaatgccgt gagacatgaa cctccttgtg cgtctgataa aaggaaatgg
     9181 tgcccgttcc tgaaaaggac ttgtccactg agtaaatctg acggatgttt gcgatcgttg
     9241 acttggaaac tcgattaaaa tagcgaggca agatagactc caactcatag agcttgaggc
     9301 gaacctcata agcttccttc tggttatgag cgtagatctt gctcccttct gtttcaaaga
     9361 agagaatttc tgacaggtct agataatatt cacctgtccc cttgtaaaaa gtcaacctcg
     9421 gagcctttga ctcttgcaag agccgttgca agtctgcaat ttcatctgtc aaagtggggg
     9481 tcttgatgac aatttcagtc tcctctaaat tgccgtcaat ctcaattcgt aacttcatca
     9541 catctccttt ctgactctac tatatcaaag ctaagttagg aatacaaggg caaaaaagca
     9601 agtggtcaat ttgaagcagt aagtggttgt aggactagct taacttacat gtcagaatag
     9661 gaagaaaagg aatccccaca ccagaccaca agcatagcca accaagacat ccttgggata
     9721 atgaacaccc cctaaaaccc tcaccaaccc cagcaaagct gaaaagatca agcatactaa
     9781 gccaataggt agactagcat gcagacaggc catggagatg atagttgcag aaaagacatg
     9841 gcgactgggc atcgaccgtc ccgaactatc cttatcaaga aggggacaga tatcccaagt
     9901 ttcataaggt ctcgggtgat tgattttctt acgaaacagg gacaaggcca caaaacctga
     9961 tgcaggaata agcacataaa ccccaacttg ctgaccaagt cctagttgca ggtaagtggt
    10021 gactagcaag atcagataga ccaggggcat ggcgactgtc atcaaacgat tgaaactgcg
    10081 taataggaat aaaagaattg gacgactagt tagtctggag ctgatatttc gataccattc
    10141 ttgataattt ttcatttatg cttctcatac ttttctagaa cttgttgaga tgttttcccc
    10201 ttggcaagcc aatccactag cttgtccaaa cgacgtattt cctgcatcag aggatcatca
    10261 atttcctcaa tatggacacc gcaaatcttc cctgtaattg caattcgttc agggacataa
    10321 tatggtgctt gtagaaaaaa atctccgtaa gtaacatccc tatccagaca agcaagaacg
    10381 tcactcactt cataccctgt caaccaactg gtcacttggt gaactgactc tgcctttcca
    10441 ccctttcgct caacttttgc aatcaaggct aagtagacag cagcaaattt catattgtat
    10501 aatttctgac tcatacttct ctctttctat gtgtactagt ataaataaga aaaagaaggc
    10561 cgtcaagcct ttttttgatt tattcttctg cttcatcttc tgtaaattga ctattgtaca
    10621 agtcagcgta gaagccacct tgcgccatca gttcctcata gttgccttgc tcgatgatat
    10681 ttccatcttt catgaccaag atcaagtctg catttcggat gattgacaag cggtgggcaa
    10741 tgacaaagga tgtgcgtcct tccatcaaac ggtccatggc tttttggatc aattcctctg
    10801 tccgtgtgtc aacagaagaa gtcgcctcat ccaaaatcaa aagcgatgca tccttaagaa
    10861 gggcacaagc aatagtcaat agttgttttt gtcctacaga caaggtcacg gtgtcatcca
    10921 agatggtatc atagccatct ggcaaggtca taataaagtg gtgaattccc acagccttac
    10981 tagcttccat cattcgttca tcactaatcc ctatttgatt atagatgaga ttgtctcgaa
    11041 tagttccttc aaagagccag gtatcctgca agaccattga aaaggcatca tgcacttctg
    11101 aacgcgtcat agccttggta tccacaccat caatgcgaat acttctctta tcaatctcat
    11161 agaatttcat caaaagattg acaatggttg tcttaccagc cccagtcggc ccaacaatgg
    11221 caaccctttg accagcatga gctgtcacag agaagtcata gtcttgaaca ttgacaccgt
    11281 ccaccagaat ttctcctgct gacacgtcgt agaaacgtgg aatcagattg accagagttg
    11341 atttaccaga acctgttgac ccaataaagg ccactgtttg accagtttct gctttaaagc
    11401 taacatgttc aataactgcc tccgaatttg ccgcatagcg gaaggtcaca tccttaaact
    11461 cgacctgacc tttgaagttt tcatcagtca gctgcacttg aacagggttt tggatagaag
    11521 aatgcaaatc taaaacttga ttaatccgct tagcagagac catagttcgg ggaagaacga
    11581 tgaagagtgc tcccatgaga aggaagccca tgacaaccta catggcataa gacatgaaaa
    11641 taatcatgtc actaaagaga ggcagacgcg ctatcggagc agcgtcgtta atcacatagg
    11701 ccccaatcca gtaaatcgct acactcaaac cacttgaaat ccccatcatg ataggattca
    11761 aaatagccat aagacggttg acaaacaaat tcaaacgggt caattcatca tttactgctg
    11821 caaatttttc attttgataa tcctctgcat tgtaggcacg aacgacacga atacctgtta
    11881 aactctcacg agtgatactg ttcagtttat ctgtcaaccc ctgaatcaag gactgttttg
    11941 gaaaggctag cgtcatcaaa acggtcgtca tcaggacgtt gacaatcact accacaagta
    12001 cggcccagag ccagtattct gaatgaccta aaatcttccc aatagcccag atagccataa
    12061 ttggaccacg cgttaccact tgcaagccca tagtaatcaa catttgaact tgagtaatgt
    12121 cattggtagt acgcgtcaag aggctaggaa ttgaaaattt cttaatctct gtctgcgagt
    12181 aatccaaaac tcggttaaaa atatcacttc tcagcctact agtataagaa gccgccactc
    12241 gggatgcaaa aaatccaact gcaactacgg acaagaaggc aagaaaggac attcccatca
    12301 tcatgcttgc cggctgccac aactcatcta aattagtttc ttgactacct agcaaatccg
    12361 taattttcga gatataggtc ggcacttcca actctagata gaccgaaaag caagtaaaga
    12421 gaatggctag taaaatcatc ccccattctt ttctactaat tcttttggct aatttcttta
    12481 ttctctcctc ctattccctt gatattttgc ctgtagttga ccgagaacct tctcaaaaat
    12541 cagtaattca tcttcatcaa tatcttccat caactgcttg tctatgcgtt caaaaaaagc
    12601 cttaacctgt tgcatctgag aacgtgcttt gtccgtcaga cgaacaaact tagcccgctt
    12661 atcaacagga ctcgcctcca attccaccaa accattttgc actatacgct taaccagatt
    12721 actagcaaca gacttggtaa tattgagttc ctgatcgata tctttaatca agaccaagtc
    12781 ttggtttttc tcgcgattat ccaaaaaatg cacaacctga ccttgcggcc cacccataaa
    12841 ttcaatgccg caacgtttgg cttccttttg caccatcagg tgaatttgat gaccaaaacg
    12901 cttaaagact aacatcggtt tacccataat ctcccccttc taaataaaaa tagttctctg
    12961 gagaataatt aaatttctat gagaactatt ttcttgatta aaaaaatccc aagtgatttt
    13021 ctcacttagg atcatgttct ataggttaaa ttaaaaccca tctacgttcg tataaatctt
    13081 ttggacgtct tcgtcgtctt caagaacgct gtaaagtttt tcaaaggttt caaggtcttc
    13141 gcctgacaat tccacttctg actgaggaat catttccaat tcagtcactt ggaattcttc
    13201 aataccagac tcacggaggg caacgatagc cttgtgaagg tcagttggcg ctgtgtaaac
    13261 tgtgattgta ccttcttgtg cttctacgtc atccacatcc acatccgctt cgagcaattg
    13321 ctcaaagact gcgtccgcat cttcacctcc aaatacaata acacctttgt tgtcaaagag
    13381 gtaagaaaca gaacctgaag cgcccatgtt tccgccgttt ttaccaaagg ctgcacggac
    13441 attggctgct gtacggttaa cgttagaagt caaagtatcc acaattagca tagagccatt
    13501 tggcccaaaa ccttcgtaac gtccttctgt aaaggtttcg tctgtgtttc ctttggcttt
    13561 atcaatcgct ttatcgataa tgtgttttgg cacttgggct tgtttagcac ggtcgataac
    13621 gaatttcaaa gctgagtttg attctggatc tggatcacct tttttagctg ctacatagat
    13681 ttctacacca aattttgcat atactttaga gttggctcca tctttagccg ttttcttggc
    13741 tacgatattg gcccatttac gtcccattag gaatctcctt ttttcacatt ttaatctttc
    13801 ttattataac acaagttttt ttgattttca ctagaggaaa tggattttat tagcaaatca
    13861 agctaggata gcactttacc tgctaagatg gtcttgcctt tctatcttta tcaacagaca
    13921 ctcatccaca ttcaaaaaac aaactagacc attatctgca aatagaaagt ttcagccaag
    13981 tttgacaaag tcagctcaaa ttactgtttg aagtttgtag atataagcga caaaaacaat
    14041 catactgcac cttttgttga cagtctactc cagacatatc atagttcaag taaatacttt
    14101 gaaattcaac agttcttata ggcgctattg tattctaaga aatcaataga agagtttcta
    14161 agcaaacctc taatactcaa taaaaatcaa agagcaaact agaaagctag ccgcaggttg
    14221 ctcaaaacac tgttttgagg ttgcggatag ggctgacatg gtttgaagag attttctaag
    14281 agtataattt acgtgttcct aagatggaga agttagacta gtacactggc acttctaaac
    14341 cattgctagc aattgatttg ttcatattta atttcatttt ttccataaat gggtattaga
    14401 tataaacagc aaaatatttc cgatacgtgt cattcttgaa tttccaatca tctaaaacaa
    14461 gtaaaggata atcaatcccc tgtatatcaa ggaattggct acccttttta cttttttaca
    14521 catcctgttt gatagactca ttttaacatc acgagcatac tccaatggaa atcgctaggc
    14581 aagagataaa ctttcagata tccgcagaga gatcatcgcc tctttttgtc gcaagcattc
    14641 tcctctccta gtcattttct accttatcct ctacctgagg atagagagtt gttccccaaa
    14701 tagaaatcgt ccgcttacgc actagtggca aatcggtttt ttcataaacc gtacgccacc
    14761 attcccaggc aagcccggta cactctctaa ttttgacaga gagattacga acattccctt
    14821 ttaaaggaat actagtggta aagtgagccg tcaaatcctg cccatttctg tcccaagcct
    14881 taggagtcaa gacttcctta ccttgatgat cataggataa ttcatcccaa gtaatataat
    14941 attgggcaac ataggcacca ctatgatcca gcagtaaatc tccgtttctg taagctgtaa
    15001 ccttagtctc aacatagtct gtactgtttt gaaaggtcgc aactacattg tcacgtaaaa
    15061 aagaagttgt ataggaaatc ggcaagcctg gatgatctgc tgtaaagcga ctgccttctt
    15121 gaatcaagtc ctctaccata tccaccttgc ctgttacaac tcgggcaccc gaacttgggt
    15181 cgccccctaa aataaccgcc ttcacttctg tattgtccaa aatctgcttc cactctgtct
    15241 gaggagctac cttgactcct tttatcaaag cttcaaaagc agcctctact tcatcactct
    15301 tactcgtggt ttccaacttg agatagactt ggcgcccata agcaacactc gaaatataga
    15361 ccaaaggacg ctctgcagaa attcctctct gttttaaatc ctctaccgtt acagtatctt
    15421 gaaacacatc tcctggattt ttaacagcgt ctacgctgac tgtataataa atctgcttaa
    15481 aattaacaat ctgaatctgc ttttcacctg aatggacaga gttaaaatca atatcaagag
    15541 aattccctgt cttttcaaag tcagaaccaa acttgacctt gagttgttcc atgctgtgag
    15601 ccgttatttt ttcatactgc attctagctg ggacattatt gacctgacca taatcttgat
    15661 gccacttagc caacaaatcg tttaccgctc cgcgaacact tgaattgctg gggtcttcca
    15721 cttggagaaa gctatcgcta cttaccaaac caggcaaatc aatactataa gtcatcggag
    15781 cacgatcaac cgcaagaaga gtgggattat tctctaacaa ggtctcatcc actacgagaa
    15841 gtgctccagg atagaggcga ctgtcgttgg tagctgttac agaaatatca cttgtatttg
    15901 tcgacaagct ccgcttcttt ctttcgataa caacaaactc atcgggtagc tgattaccct
    15961 ctttgatgaa acgattttca atactttctc cctgatgggt caagagtttc tttttatcgt
    16021 aattcatagc tagtataaag tcatttactg ctttatttgc catcttctac ctcctaataa
    16081 gttcctggat tgagttgcat aaactcagac ttgttcagcg aaatcagccg tggttggact
    16141 aagtgatcca aaatttcctc gtacaattct tctgagacat tgcgtcgccg tctggctaga
    16201 taagaagtcg gaataaccgt attatccaac ataaatacct tatctaagtc aatcaaggtt
    16261 ggtcttgtaa aaggattacg agctagatcc ggctcttcta tcataaagtt cttgaccaaa
    16321 cgtctggtca agagagctgg tttgaaggtc tgatttttaa ccaactcttt gtttttagtc
    16381 atgctgttgt caatacagat atacatatga ttcttcacag ccaaatcgct actaatagtc
    16441 ggaaaaggca aataaagagc tacaacatct cctctcttaa tcaagcaaga gcaccccctt
    16501 ttctcctaat gtaacataga caggattgac caagtcttct gattgactca gaatttccaa
    16561 agtttgagtt tggcgcgctg tcaatttagt agcatcttgt ctcttcaata caaaatgctt
    16621 gtcgccaata accttgacaa tataatcctt ctccaaagct gactggtaaa tccacatcag
    16681 atgttgtctg tcctgagaac tcaagagaga aggattttca agcctcccga tagtctgata
    16741 aaaatcaaaa acaggagcta actcctgcca atctgattgg ctagttgtca aggctagaaa
    16801 aagggctttg cgagctgata cttcttggtt agccttgaga gttactttcc cctccaagtt
    16861 ttttagaaat cgggaaactc cagaaagcaa atttttctct aactgcgaga aataaaaacc
    16921 tttcgttccc agacataagt ctttcatgtc gctttctcta gcaaataaga gctcaaacat
    16981 ttgatagtaa aagaaaaata tctggcactg ggtcgcgctc atcttttcct tatcggcttc
    17041 tttttttaac cagagcaagg gcgacaggta actggattga gacatttcct ctacctccta
    17101 ctctttttta actggagcat ctgcactagc tgccacttct tttgactgga tactttccca
    17161 ctggttaatc tcctctgaga taagaccttc gcatgtcttg acaaataggg caaaagcctt
    17221 ggtctttcct gcatatttct ccgtttggca ttgatagagg aatttttctt tctccaggag
    17281 ttgcgcagtt ttttggtaag aaatccaatt ttcctttgca ttatacaaat tgataatccc
    17341 ctcacacagc aagccgagac tggataaggc aaccgaaatc aaacggtagc gatcacctgg
    17401 cataggaata gcacaaaaga cagctatgag gaaacctgcc acgatttctg ttatttttaa
    17461 taccttatag cgcctacgat gttgaacgct tttctttaaa aaatgagcta tctgtacgtc
    17521 taatcgctct gtcaggtaca tttcttctgg cgtcatattc gtaactcctt tcatttactt
    17581 tgataaccat agtataacat atttgaatat caaagtatag taaaaactgg actataactt
    17641 attagacttc ctgcgaaaca aaatatggta tagtagttct atgaatgatg aagcaagtaa
    17701 acaactaact gatgcacgat ttaagcgtct tgttggtgtt cagcgtacca cttttgaaga
    17761 gatgttagct gtattaaaaa cagcttatca aaaaagtcgg acaagctggt aaaatcttgg
    17821 ctgacagtaa ttatcaaggg ctcatgaaga tatatcctca agcacaaact ccacgtaaat
    17881 ccagcaaact caagccacta acagttgaag ataaagtcta taaccatgcg ctatctaagg
    17941 agagaagcaa ggttgagaac atctttgcca aagtaaaaac gtttaaaatg ttttcaacaa
    18001 cctgtcgaaa tcatcgtaaa cgcttcggat tacgaatgaa tttgagtgct ggtattatca
    18061 atcatgaact aggattctag ttttgcagga agtctattat atatatgcac agacatatga
    18121 aatctttttg atacagcctt ctttttacat agagagacag cagttatgat atatttatcc
    18181 attcacaaca tcttctgtac caatactaca ataattggta cattttgatt acacaatcgt
    18241 ttcaaaaaat atgatggaag actgagtatt ttatagtaat tcccttccta tcaactagat
    18301 caaccagttg agtgttgaat gttgaaacac cctagcctca gcaaaggact atgatcagca
    18361 tttcctagcc aataggacgc tccaaatcac ctattctaag tccatcacta gcttggtcag
    18421 taagatacag actgcaaggc aagactgacg tggttgatga gattttggaa gagtattaca
    18481 atcatagatt caccagtaga cttgaccgca gatttaacta tagtagattg aaactagaat
    18541 agtacacttc tgcttctaaa acattgttag aaatcgattt gactgtcctg atcaatttgt
    18601 cctgttctcg tttcatttta ctatactaaa aaaccacctg aaacaaatca agtgactaga
    18661 ggataaaaac aaagactggg caaaaagttt tgaaaagcaa aaaacgcata atatcaggtc
    18721 ttgaaaaacc ttgatactat acgtttgatt gtgggaagat tgacttcatt ttctcctgaa
    18781 attgaagttt tttctagttt ccaggtatag acgaattcaa tatagccatc tcgctacaat
    18841 tattttaacc atcgaaaaaa tttttcagaa tttcaaaaat ttcattttga tccaatgaaa
    18901 tgtcattatt ttgaagaata gttgacttca caggctctaa ttctatcaca aagcggtgca
    18961 tgtctgcttt taccgcacta cttgatgtta tagccgataa cttttcatct cctagcaagg
    19021 aagctgtcaa acgggtaagg tcattcaaat gctttttaat ggacttactt aaaccttgag
    19081 cacctgtggc agagcgctcc ctcatatcca gccaagcttt agccttaaaa ataattaata
    19141 ctcaatgaaa atcaaagagc aaactaggaa gctagttgca ggctgctcaa aacactgttt
    19201 tgaggttgta gatggaagct gacgtggttt gaagagattt tcgaagagta tagaccacaa
    19261 ttactcaata ccgaataccc ctgaatggtt tcttttacat gcaccaatat attataataa
    19321 tcttcatcca ataataaggc tgataaacta gcatcttggt caaaatataa gggaatttct
    19381 cgaccgtcct tctttaatgg atattctggt aagatactaa atagttcaat catagaagga
    19441 aactcagaat tagttgttgt aaatcgaaaa agctgcgctt tctcatcttt ctgacttcct
    19501 tgatactctc ccaattctaa aaaatgattc aaggtagtat aaaattcctt attttttact
    19561 tcatcaatga tgaccatatc ataatctttt gttgtgcgac ttttaaatcc ttgcgaatcc
    19621 aatacgatag aggtagcagt tcccccaatc agaacataat agttctgaaa atccgcaaac
    19681 atttcttgaa aaataacttt cgtattagct ggcatcatct tctcccagat actgtaatat
    19741 catattttct agtgcttcac tctcttcctc tatacgtggg tcatcatcat cttttaaggt
    19801 caaataaaga gaaatcggat ctacaaattg tttatcatga ttatttttaa aatcattcca
    19861 aaactcagat acaaaaggac gatatttcca tatctctagc atctttcatt ttaaaacatg
    19921 ctgagaaagt ggcaaggata actgattgaa ttttctctgc catatgacat agctaatatt
    19981 ttcatccgtt tcagctaaaa aagttgaatg cgacaaagca taagcaccac catatagaag
    20041 gttagaaaca gattttatct gctttatatc gccatctggc aataaaatcc gttttttgat
    20101 gggattaaat aaacatgaca cggattttaa gaataattct ttctttgaca ccgtatatgt
    20161 gtaaagctta ttttgcttgt ttaaccaata taaagcttta aaagtcctca aacacctata
    20221 aattgttgag tttggaagtc cagtgacttg tgaaagcaaa tcaacatcta ctactttttg
    20281 accttttgtc aataaaaagg caatccacgt taattgttcg ctaggtgtta attccttagg
    20341 gacttcagta tcattcgcat tgagtactag tcccaatgga gggaagaaga ggtttccctt
    20401 aaagtctaca aacggaactc tagcttgaag taattgcttt ttttcactgt ctgataactt
    20461 cgaaaacacc aaaacaacat ccatattggc tttttcaccc atagtgcgag cctgagtaac
    20521 aaatgaactc aaactccccc ttctcttttc tttaatcaat aaaaatgatt ccttatgaaa
    20581 agtcatttga gtatactcaa acctttttac aaaactgatt ggtaaagtca aagtcagttc
    20641 ctcaatactg acatcaacat aaaaggattg aaaaattgac attatctttt tgacattcat
    20701 gttttttcct tattctatca tttttattat attttatcat tcggtataat aaaatataag
    20761 ttttttgata aaataaccaa aaactactcg ctatcccctc tcacattacc ctacatatcg
    20821 tttgacatgc gactgatagt tcaggaaaac ttcaaggaga acttttctct catccactat
    20881 gcaggactta ctatttcact tctactccta taggctcaat ttgacacttt tctttttcga
    20941 attgctcata tgcctcctga atagtgagtt cgatttatcc aaatttattt ttgtctattt
    21001 tgatgaatac ttccacgaag atagtctgaa aatgaatttg caccaatttt ccttctcttt
    21061 ttaagcatat tattccagat atgattgccc tcttgttcag taataaatta cgctttaaac
    21121 gcttcaatca gtatatctcc tgttgtcata tgttctaaag aaaattcttc tacatatgat
    21181 ttaacatctc ttaggttatt acttcctaat atcccattat gctttttcgc taaggaaata
    21241 gaagccgctt ctcccttacc aataatcttg ttattatcat gatttcttgt taaatctcta
    21301 tataatgcgt attcttcagt tccaatgtct atgctcacaa tctcagctga acccttagct
    21361 accaactgat ctatcctaga ttttaaatgg ggaattgtag gtatattgat ttcatcatac
    21421 acctcttgtg gaataacaat tttacccgaa tagagctttt ctaaaagatg ttcagtgcca
    21481 acccataaaa atactgaaat acaatctgca tcaataaata cacgactagt caaacgacaa
    21541 ctcccccctc ttcatctagc ccatatacaa tatcatatct gaaagcatct agtaacagtt
    21601 cctcatactt cccttgcgaa attctgttat tttctaaaag ttgttcagtt gaattaatat
    21661 attatcctaa taccatttcc tttttacttt ctgacaaagg acgatataaa cttgtatcat
    21721 agcctaatct tgaagctgtc tctataacac taatatccat atttttaatt tcttctgcat
    21781 caaggtatcc atcattcctc aatctatata acatagcttt atgactgata ccataaaact
    21841 gacccaattt tataatatct tctacttcaa gatgagttct attggcattt tctctgattt
    21901 cctcaaccat cctatacagt gaagatggga aaattaaaaa ataagaagca agctgatccg
    21961 cttttctttc agtttcatct ccttcaccaa tcaagataag actgactgaa ctcttcttca
    22021 cctcatcata ataaagatga tacagttcat gtgctaaaga aaatctttac cttcctaatg
    22081 acatgtctga attgactgca atgagactga actgagttcc tttataacag actccgctaa
    22141 tattctttcc gagtccataa aataccagcg tcaaattttc tatcttttgt accaatttaa
    22201 aaatatctat cggcgcttca ccatcagctc ccaacttttt tctaagattt gaagctttat
    22261 tacttaaatc cattcgtgat attcctttca cctttttcca ttttggcaat catgctttga
    22321 ttcaaagaca aatataaaga caaatattca gcaatcttat cttgagtaag atttgaagat
    22381 attctaagtt cttttattct ttttccaaca tcacatacat ttatcacata catttatcat
    22441 attcatacac ctctcataaa aagaatagca cacttttgtc ataatttttt aaataaaaaa
    22501 attatgacaa aacaaggaag caatttattg atgctgctta aaaatctaaa attgatgagt
    22561 tcctatcaaa aatcgtatct tcaacctcaa aacagtactt aaagctatcc gactcggttt
    22621 acattgtcaa atttagattt tatttgagca taactttcta gtttgctttc tgatttttgt
    22681 ttaatatagt agcaaacatt gaaggaaata tctccacaag aaaacgcata ctattaagct
    22741 ttttcaagac ctaataatat gcgctgttct gatttgaaag acattccatt attattttac
    22801 tgtaatcaag ccatctggct ctactgtgaa ttctggcctg tctgccagtg ttccgtctgg
    22861 tttgaggtag taccagcctg ttccgtccgc tgactggata aaggcatttg ataccatggc
    22921 gccttcttta gcgtctaagt agtaccaagt gtccttgtac ttgacccagc ctgtcttcat
    22981 ggcaccttct tcgttgaaat agtaccactt atcagcgatt ttcttccagc ctgtagccat
    23041 ttcgcctgag ttgtcgaacc agtaccagtt gccgtctgtg tgcttcctcc agcggtctgc
    23101 aagcatatag cctgaactgt caaagtagta ccaagtgcca ttgattttct caaacttgtc
    23161 ttttggataa gagccgtctg aatgtacgta ccagtagcca gtgtcattct tctgccagcc
    23221 tgtttcaatc gtcaagccgt tctcaatatc atgcttaaac tgctcacggc taatgcccca
    23281 tttagcaaga tatggataag ggtcaacgtg gtctgagtgg ttgtttggtt ggttattcgt
    23341 gcaatactcg tgcgttttaa ttccagctaa actccctgta tcaagcgttt tcggcaaacc
    23401 tgcttcatct gctagattgc gtaagagttc gatataaagg cggtagtccg tcatgaactc
    23461 ttctttggtt gaatggcttt caatcagttc aaccgctgca taggtctcag cattccaacc
    23521 gcccccaacg tcccaggcac cattatcaac aggtcctacc tgcatgatgc aaccgttccc
    23581 aacaatgtgc gagaaaaaac ctaattctgg gtctttccgc cagtgataat ccgcttcatt
    23641 ctgtacggtt gaatgcggat tcccagttga gtgtgcgtgt acttgcctat atggttgcac
    23701 gccgacttga ggcaaatctg ttcttaattt actcacatta atttccatat tctactcctt
    23761 atcaattaaa acaactcatt ttttacaatc cagaaccaga aactccttta tttctacctt
    23821 acaaagaaga caatcttagt cacgattagg cttgtagata gaacttcaaa acgcactatt
    23881 ttgacactgt aaataggact gacaaggtct gcattctatc tacaataaca ccccagacta
    23941 aaaagctttt caaaagtata tttttacagt ctctatatgt ccttttcata aatactatac
    24001 tttattatat catataaaag aagtcaaaag tctgttaaac tattttcaac accaaactaa
    24061 agacgagaac acaagttttt tcgattttca ctagaggaaa tggattttat tcagtaaatc
    24121 caactaggat tgcactttgg ttgccaagat tgccttgcct tcttttatca agggatgacg
    24181 gaataatgag aagtacagtt gaactgtcat ggcaacccag ataagaggtt cacaaaggat
    24241 aacaccctta tatcctgccc aaggaataat caaaaccaca aaaacgattt ttccgattag
    24301 ttcaataaag ctagaaacta gaggaaggat cttttgcccc aagccctgca agcaattgcg
    24361 ataaatcaac aagaggctca aaatgggata aaaggttgaa ctgatttgca gatagagact
    24421 tccattttct atcaagtaac catctgtcga actagccaag aaggaaacca aagctggact
    24481 ggcaaaaaag aggaaaatac aaacaaaaac tgcccaggat atacttaaac gactgccgat
    24541 tcgaagacct tgaacaatac ggtcaggtcg cttagctcct agattctgag aagcaaaggt
    24601 cgtcattgat gcagaaatag cggtcatagg aagaagggca aaggtcataa tgcgtcgagc
    24661 tgccgtctgg gcactaataa tcactgcacc aaatgtatta acagaaaact gtaaaatcac
    24721 actgccgata gatacaattg aactcatcaa gcccatagcc aaaccttgct ccaagagatc
    24781 cgcgtacaag cttttgtccc atttgaaatg tttaaactgt ggcaagagtt ctggcacact
    24841 tttacgaata taataaaagc agagaaccgc tgataaacct tgcgaaataa tggtagcaag
    24901 tcctgcggat tgaactccca gatgcaattg cgtaataaaa tagagatcca gaaccacatt
    24961 aaccaaggca gagaaaatca gaaatcccag ggctgctaga ctgtcaccaa tagaccgcaa
    25021 caagcctgca aaaagattat aagcaaagct gacacctaca caggtcacaa tcatagaaat
    25081 atattgataa gattgaggaa gaatttctgc aggagtatct aagtattgca agagaggata
    25141 caagccaaga aagcccagca acataactag aatgctcaaa agagcaccta aaatccaggt
    25201 ggctgctact gcttccttga ttttagtgaa attccgagcc ccataataac gagcaatgac
    25261 aatccccatg ccattgccaa caccaagtgt aaagcctaca atcaggtcaa aaatcgctgt
    25321 cgtcgctcct actgcagcca aggattcttg accaagaaat cgtccaacaa tcaagacatc
    25381 agcagtgtta tagagctgtt gaaaaatatt tgatagcaag attggaaagg tgaagcttaa
    25441 gagcgaggga agaatcggac catgtatcag gtccactgtt cgttttttat tcataaagct
    25501 attatatcag ctttccagag gagcgacaag aaacagcaaa cttatatata gcggaatgaa
    25561 ataaggacag tcaaatcgat ttttaacaat gttttagaag tagatgtgta ctattctagt
    25621 ttcgatctat tatagttggt tgagtttgga atagtacgct gtagctgcta aaacatttct
    25681 agaaattaat ttgactttcc taataaagtt gttcatatct tatttcaagc tactatatat
    25741 aatatataat ctaaaaactt gaatcaaaaa tcgaaaaagt agcggatttc tccactgctt
    25801 taacagctta ttcttcaatt tcgatttcaa gttcatcgcc taagtcaagc ggaacttctt
    25861 cattcactgc ttcttctttc tttggctcat cttttttgtt ttcagtatct tgttctgaaa
    25921 cttcttctcc atcaatcaag ccaaatttag aacggacttg cttatcaatt tcatcaaaga
    25981 tttctgggtg ctctgccaag tatttcttag cattctcaga accttgccca attttttcat
    26041 ctttgtaaga ataccaagcc cctgcttttt tgataatatc caaatcgctt gcaatcttca
    26101 aaagctcacc agtcttagaa attccttctc cgtacataat ttcaactacg gcttccttaa
    26161 acggtggagc taccttattt tttacaacct taatcttagt ttctttaccg acattggttt
    26221 ctttttgatc accagttccc ttaatttgtg tattaccacg aacatccaag cggactgaag
    26281 catagaattt caaagcacgt ccgcccggtg ttgtttctgg atttccaaac atcactccaa
    26341 ctttttcacg caattggttg ataaaaatgg caattgtttt ggttttattg atagaggcgc
    26401 caagtttacg catggcctgg ctcatcatac gagcctgcaa accaacatgg ctatctccga
    26461 tatctccatc aatttccgca cgaggaacaa gggcagcaac tgagtcgact acgacaagat
    26521 caactgcacc tgagtcaatc aattttcccg caatctcaag accttgctct cctgagtctg
    26581 gttgagacaa gagcaattcg tcaatattga caccaagggc cgcagcataa gctggatcaa
    26641 gggcatgttc cgcatcgata aaggcagcaa tcccaccttc tttttgcgct tgtgcaactg
    26701 catgaagggc aaccgttgtc ttaccagatg actctgggcc atagatttcg atgatacgtc
    26761 ccttaggata accacctgag ccaagggcaa tgtcaagagc taaagaacct gagctcatca
    26821 cttgcacctt ttgctccgca cgttcaccca aacgcatgat tgatccttta ccaaagtctt
    26881 tctcaatcaa tttaagagcg tcattcaagg ccttttcacg ttctgcccca aatttttttg
    26941 aaatttcttc taattttttt ggttttttcg ccattctatt ctcctacatt ctaatgatcc
    27001 tcagacctat ctactattat atcaaaagtt agtcacttaa taaagccttg cgaactaggt
    27061 taaaggcatg cataaccgca atgtgacgta catctgctcg gcttctgcct ccaatattaa
    27121 ccttgataac ctcagttcct tgatcttgcg ccaagcctat gaagactgtc ccaactgggt
    27181 gtccttctag gctatctggt cctgccactc cagtcaaact aattccaaaa tcagactggg
    27241 tcttgcttcg tgcctgctca gccatcttct gagctgtaaa ttcagacacc acaccatgtt
    27301 cttccaaatt cttggcagga atatccaaca tccttgattt ttcctccaag ctataggtca
    27361 caaaaccacc ctcaaatata cttgaaactc cagaaaaatt cgccacggta gcttggaaaa
    27421 gacctgccgt caaactctct gcagccgcga tggttttccc ttgccttttc agttcttcta
    27481 ccacaatgct ggctaaacta gtttcttccc cataaccata gcaaaagtct cgtaaagaaa
    27541 ttccttcgaa agtctggcag tccaagattt gattttccaa gatatccagc gcttgattcg
    27601 cctcttcttg actgctagcc tttgttgaca gacgtagagt gacttctcct gtcttggcat
    27661 aaggggccaa ggtaggatcg atctgattat caattaaatc agccaaaatc gtaaccaact
    27721 ggctctcgcc aatcccaaag aaacgaagaa ctcgggaata cagcttgctc cctgtcatca
    27781 acttgggtag aagttggttt aagaccatgg gtttcaattc acttggcgga cctggaagga
    27841 cgacataggt cactccgtct acttctaatt ttcctccaac agccagtcct gtttcgtttg
    27901 gcagtggaat cgctccttct acaatttgag cttgtctttc gttattcggt gttcgggcat
    27961 agtctggtcg cagggcaaaa aagatatcca acttctcctg agcctgagga tcaaagacta
    28021 atgctttccc taaaaattta gctagggttt gtttggttag gtcgtcctca gttggcccca
    28081 aaccgcctgt caaaatcacc agactgctac gttgactggc aatctcaagc aaagacaaga
    28141 gacgaacttc attgtctcct acagccgtct gaaaatatac atctacccca atctcagcta
    28201 gtttttccga caaaaactgg gcattggtgt tgacaatctg tcctgtcaaa atctctgttc
    28261 caacagcaat gatttctgct ttcatgtttc ctcctaccta tctattcgta tttttttgaa
    28321 aaaatcgcag gaattttcct acgattgatt tttttatttg tatcaaaagt taattatctt
    28381 catcaccaac aggtgctctg ccaaataaat cttcaaataa aaccgcattg gtttcaagct
    28441 gagtaacttc ttcttgtccc aaagaacgtc ggagtatatt ttgcatttcc aacatatgtg
    28501 ctctcgaaac aatctggtaa gaaacacctt gaagtatctc tccttcaccc tgcaactgct
    28561 gagtttcaat ggttttaaat gaatctttat agcctagcaa gttagggata ctttttgcag
    28621 acaaatcaat attggtctgc atattgtcac tcaaagcttt tagaatctct tgataatgac
    28681 caatgctatt taaactgaga gctttttcca tgactttttg aataacttca cgttgacgtt
    28741 tttgacgacc ataatccccc tcaggatctt ggtaacgcat tcgtgcatag actagggctt
    28801 cttctccccc aatatgttgc tccccaacac cgatagaaat ggtattaaat tcttcttggt
    28861 cactgataga aattgggaaa cctaggatat tattgactgt aatacctcct actgcatcca
    28921 ctaatttttg caaccctctc atattgacca tcacatagcg atcaatatgg atattcatca
    28981 ttttttgaat ggtttctata gcaagctctg ctccaccatc tgcatatgct gagttcagtt
    29041 tcgcttcatg agcctgacca ttccctgatt caatgcgcgt cagaatatcc cgctctaaac
    29101 tcatcattgt tgtttttttc gttttaggat tcactgtcat caagatcatg ctatcacttc
    29161 taccgaccca agtttcagtt cgttcaacat ttccggtgtc cactcccatt aacagaatgg
    29221 ttagaggttc agtcgcttca ataaccttgg tttcttcacc gattttttta taggttttag
    29281 ctaaggtttc tgtcccttgt tgataaatag tataagcaaa aacacctact cctactacag
    29341 ttacagaaag taaagctagc accattccaa taattttttt aaccatattt ctactaacct
    29401 atcagtttac ccatcaagta aacatcgata aatttccctt cttctatata tgccccacgc
    29461 tcttggctac cttcaatgac aaagccatgc ttttgataaa gatggactgc tgcttgatta
    29521 cgagtttgga cagtcagttg gagacgacgc agaatgccac ttgcttgtgc ccactctatc
    29581 gcttcttcta gcaacaaact tcccaagcca ttattccaat atctttttcc aatcacaatg
    29641 aagagatctc caatatgacg gactctctta cgctgatcag ctgtaatatt tacaatacca
    29701 gcaattttgc catttaagaa tgcaagtaag gttatctgat tgtccgaact agcttgcttg
    29761 ttgaggaata tttccatctc ctcactagtc aagagaatac catctccgtc taggctggta
    29821 aagtctgtct ccaaactcac acgatttaaa aaggccacta attcagctgc atctttgggc
    29881 tctgcttccc taatgagcaa ttcatactcc atattgaagc tcctctaaca atttctcagc
    29941 acgcaaaccc tttgcctgaa aatttaaacg gcgtccatct gcttctttta gaatttccaa
    30001 ttctaaataa gcatctggca aggcatctcc taagagattt ccccactcaa taacagtcac
    30061 gccgccacca aagataaact catccaagtc gatagaatca gcatctcctt caatacgata
    30121 aacatctagg tgataaagtg gaagtcgacc ttcatactct ctcacgatag tataggtggg
    30181 acttttaatc atttgagaaa tctgtaatcc ttttgcaagt cctttagtaa aggtcgtttt
    30241 acctgcaccc agttctccag ttaagattaa aacatcattc tttgctaata gatggcccaa
    30301 acgctcccct aaggcttgca actcttcttc attttttgtg tacatactct tattatacca
    30361 aaaacttttc ttttgtgtct attttcctac taaacttatc atcataacat ccataaaaaa
    30421 caggctttct ctaaaagaaa atgagcgtaa caatgaccaa tacaagatct cggaaaatat
    30481 gaccataaaa ggaaacttcc ttcttaaccg aatttgggac aagataggct gcaaaaaaca
    30541 agcccagtcc aatataaatc agaagtgaga caatggtcat tggatttctt aagaaaagaa
    30601 gtgttgctaa aatagtcacc aacactgtct tttttctgtc cagcatagca agaaaatcgc
    30661 gcacgtattt tttcaagggt aaaaaaatca gcaaatctag cccaaatagg aaaaagaagg
    30721 atggcaataa aaagtcaact aattcttgct gcagcgtatt tttgatgaac aagttatctg
    30781 acaaaacaag aacagctcct aacaaattaa ttaagagtaa catactgtaa aaaagcttca
    30841 ccgacttctt actggctagg acactatgga cttcttgctt acgggtataa agataattta
    30901 ctccagcaca gattcctgaa acgaaaacca tgcttccgat gaaaaaagct gtactttgtt
    30961 taaaggacaa gatgcattcc ttccatagga aacagctact caaactgatt tgaattaaag
    31021 ctaacaaaaa taagattctc attgatttca tcttctctct cccttcctac caatcattat
    31081 actaggagaa aagagagaac tgtttctaat cttctcaaat gtctctttaa gacgctaaac
    31141 aaacactaga gactaatact caatgaaaat caaagatcaa actaggtagc tagccacagg
    31201 ttgctcaaaa cagtgttttg agattgcaga tagagctgac gtgatttgaa gagattttcg
    31261 aagaatataa atttgaaatc atgaaaatcc gtcaaacggg tgattgtttt gtctcgcacc
    31321 tcacggagcg agacggactc agagtcacat aattataagg ctgatagtat taatctaact
    31381 atcagcctta caggttattt aacgtttcag aaaaactata atgtcaagat taactaaaca
    31441 gtatctagtt ccttcaaata attttctatc ttcatcaaca ttaaaggatt gttataaatc
    31501 ttacataact ctcttgcttc tatataataa tttttgactt gttctctgtc tagaaatttg
    31561 gctccagcat ttcctacaag aataagtaga ggagccaatt ggtagcttgt ctgtctttgt
    31621 ttacagagtt caatcgtttc aagagcttct tggatggctt cattatattt ttcctttgat
    31681 actaggtagt gagcgtagtt gtaacgaact ctgatgtagc caaataaaaa ctcttgatgg
    31741 tccaaatttt ttgtctgata caactctatt aaatgagagt agtttgcctc atattcttgt
    31801 tcacgaccca ctaaggaata gaaattagat agagtattca acgcctttaa ataaatcaga
    31861 gtatttgaag agacttttaa taatatattt tccaatgacg aaattgcctc acacttactg
    31921 tcatattgat agaagtcaat tatagattta atccattcaa ggtaagttcg gtcttctaat
    31981 gttagaaaag tgcttcgttc tacctctatt ttataaagat attctaaatc gtcataattt
    32041 ctgtcatcta ataggcgagc agatagatgt ttgaaattag agaggttaga cttaacttcg
    32101 atttgttcat tgaaaaagta atccaaaggg acttcaagtc gttgagagag tttgaataac
    32161 aagtctgcgg agggaataaa atgacctctt tcaattttac taatctggct ttgttcacaa
    32221 attccttctg caagagtttg ttgggagagt ctcaactctt ttcttttcaa tctgaatttc
    32281 tctgcgagtg tattcattaa agataataaa ccttcctatt tgcttaattt cattataaag
    32341 tttttag
//
LOCUS       DAVKMJ010000029        25344 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000029 DAVKMJ010000000
VERSION     DAVKMJ010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25344
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.029"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..195)
                     /locus_tag="VW348_001365"
     CDS             complement(<1..195)
                     /locus_tag="VW348_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000973716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746255.1"
                     /translation="MLIVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLK"
     gene            complement(203..574)
                     /locus_tag="VW348_001366"
     CDS             complement(203..574)
                     /locus_tag="VW348_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
                     /protein_id="HEU9746256.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WIFTNIIDGWDGRRDNQLRIG"
     gene            1332..1652
                     /locus_tag="VW348_001367"
     CDS             1332..1652
                     /locus_tag="VW348_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU9746257.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICRDDAKLIQKGFSLLELTEETSILFHLKKEVEIYYQ
                     AKER"
     gene            complement(1941..2411)
                     /locus_tag="VW348_001368"
     CDS             complement(1941..2411)
                     /locus_tag="VW348_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HEU9746258.1"
                     /translation="MRMPLKHPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVSVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQIGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(2377..3183)
                     /locus_tag="VW348_001369"
     CDS             complement(2377..3183)
                     /locus_tag="VW348_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEU9746259.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(3399..4040)
                     /locus_tag="VW348_001370"
     CDS             complement(3399..4040)
                     /locus_tag="VW348_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9746260.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(4037..6145)
                     /locus_tag="VW348_001371"
     CDS             complement(4037..6145)
                     /locus_tag="VW348_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU9746261.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(6197..6484)
                     /locus_tag="VW348_001372"
     CDS             complement(6197..6484)
                     /locus_tag="VW348_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEU9746262.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTGMEYFYGFE"
     gene            6909..7229
                     /locus_tag="VW348_001373"
     CDS             6909..7229
                     /locus_tag="VW348_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEU9746263.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVPIGICTDNAKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            complement(7282..7854)
                     /locus_tag="VW348_001374"
     CDS             complement(7282..7854)
                     /locus_tag="VW348_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEU9746264.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            8096..8767
                     /gene="sdaAB"
                     /locus_tag="VW348_001375"
     CDS             8096..8767
                     /gene="sdaAB"
                     /locus_tag="VW348_001375"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEU9746265.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            8776..9648
                     /gene="sdaAA"
                     /locus_tag="VW348_001376"
     CDS             8776..9648
                     /gene="sdaAA"
                     /locus_tag="VW348_001376"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEU9746266.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            9670..10302
                     /locus_tag="VW348_001377"
     CDS             9670..10302
                     /locus_tag="VW348_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU9746267.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            10352..10429
                     /locus_tag="VW348_001378"
                     /pseudo
     CDS             10352..10429
                     /locus_tag="VW348_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(10695..12545)
                     /locus_tag="VW348_001379"
     CDS             complement(10695..12545)
                     /locus_tag="VW348_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEU9746268.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(12587..13744)
                     /locus_tag="VW348_001380"
     CDS             complement(12587..13744)
                     /locus_tag="VW348_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9746269.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKEDIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKRTIIYLDKISQINQNML"
     gene            13802..14968
                     /locus_tag="VW348_001381"
     CDS             13802..14968
                     /locus_tag="VW348_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEU9746270.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            15107..15433
                     /locus_tag="VW348_001382"
     CDS             15107..15433
                     /locus_tag="VW348_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU9746271.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            15420..16013
                     /locus_tag="VW348_001383"
     CDS             15420..16013
                     /locus_tag="VW348_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEU9746272.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYATRFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            16006..16917
                     /locus_tag="VW348_001384"
     CDS             16006..16917
                     /locus_tag="VW348_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEU9746273.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            16980..18044
                     /locus_tag="VW348_001385"
     CDS             16980..18044
                     /locus_tag="VW348_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746274.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQLEEEVPQAEVELESQQEEKIEAPEDSEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(18222..19082)
                     /locus_tag="VW348_001386"
     CDS             complement(18222..19082)
                     /locus_tag="VW348_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HEU9746275.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFERVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(19357..20343)
                     /locus_tag="VW348_001387"
     CDS             complement(19357..20343)
                     /locus_tag="VW348_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEU9746276.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEEREQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(20615..22090)
                     /locus_tag="VW348_001388"
     CDS             complement(20615..22090)
                     /locus_tag="VW348_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEU9746277.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(22300..23223)
                     /locus_tag="VW348_001389"
     CDS             complement(22300..23223)
                     /locus_tag="VW348_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9746278.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(23237..24166)
                     /locus_tag="VW348_001390"
     CDS             complement(23237..24166)
                     /locus_tag="VW348_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9746279.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGTLWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(24485..24705)
                     /locus_tag="VW348_001391"
                     /pseudo
     CDS             complement(24485..24705)
                     /locus_tag="VW348_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(24659..24919)
                     /locus_tag="VW348_001392"
     CDS             complement(24659..24919)
                     /locus_tag="VW348_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746280.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
BASE COUNT         7711 a         5449 c         4497 g         7687 t
ORIGIN      
        1 ttttaaaaaa cttaataata aatttgctcc actgattgct atcaatattt caattggtaa
       61 aaaatagtaa ttccaaataa aatgagaaat cagcaatgat agaaaaataa caatatcaat
      121 tttcctgttg ttgacatact ctgtaatttt atgatacagg aatgcaacaa taactgaaat
      181 taaaacaatc aacataagat tattaaccta ttctcaattg attatcacgt cgcccatccc
      241 agccatcaat aatattggta aaaatccaat cagctccagc accaattcca gcagatgcaa
      301 tacttctaat aacagtattt gcaaaagcat ttccaatatg aattcctaat actcctaaac
      361 ctttaacaat cccagctacc agtgcggagc gtaatccata agatgcaaga actagttgaa
      421 ggcctccacc tcctgctgct gctaatgctg catatgctgc accagtaatg gctcctgtaa
      481 ttgcccacct gggtatatat atagcccccc catcaaggta catcatctct tcttcatcaa
      541 tcacaacata attatttggt aatacaagtt ccatttattt tctccttttt tattaagcat
      601 gcttaggatg gtttcctaac aagtgatcgc aggctttgtt tagttaccta aattagactt
      661 ccttccttta tcttatttta aatatttaaa accagttact gcttgaagct taacagttta
      721 cttaattcaa ataacagcta atcactgatt ccctgatttt atcaaatata ctaataacaa
      781 caattgtgat acgatcatca ttataagaac aacatttaac gaatcaaagt ttttccgaga
      841 taataataaa gcaacagcaa gcagtattat tactaaagat tgaataacta ctattactct
      901 taacatttta tcctccacta acaactcaag ctcccttaca ttatatcgac cagccccatg
      961 gaaagattat agctagacta atcaatgata taatacatac tagaatacaa aatatttttt
     1021 tattcatact ttttctccta tctttatttt ctacctacat catacctctt attaagctca
     1081 tttcaaaatt acgttaactt ttttcacgaa aaggagacaa ttatgcgtta tgattatgga
     1141 tagcgctttc aaatttttaa actcctatcc catcctttta tctatattat gagcgaaaat
     1201 ataataactg tcaagtaact aaagtgaatt ttataaaaaa attacaagcc aaatttgtaa
     1261 agtttacact aagccgctag ggcaatcgtc tatcagaatg tccgtttatt tgtcaataat
     1321 ccgagaaaat cttgcaacgc ttagaagtct ataaaaacta tcaacattta tatgacttgc
     1381 gaatagcaat cctgctcaac ctttccacac tctatctata caatcaagat aaaaacatgt
     1441 gtaagcaaat ctgctacact ttactggagg acgccaagaa taagaaaagc tacgataggc
     1501 tggctatctg ctatgtccgt attgggattt gtagggatga tgcgaaactt atccaaaaag
     1561 ggttctccct tctggagcta accgaggaaa cttctatact gtttcatctc aaaaaagaag
     1621 tagagatcta ttaccaagcg aaggaaagat aaaaaagccg agggatttcc tcgactcttt
     1681 acatattatt tgttcgttag ttcttaatac cagctattgt taagccagaa gtttttagct
     1741 ctgccaagcc acatagtgtg tttactacta tgtgtccatg tcaccatgaa tcgccgaacg
     1801 atttaacgag aaagtatgac ttttccgttt atcccaactc aattatgaca tttttttcaa
     1861 aagtcaatat atctcacttt ttcaacgaca agaaagaggc tgataatcta ccaacctctt
     1921 attctgaacc catcactcca tcacttttta gcttcattcg ctttcttagc gactgcaatc
     1981 tggtattcga cttggtcatt ccccttaccg gtacaaccat gagcaattgt agtcgctcct
     2041 atctgatgcg ctatttcaac caatttttta gaaatcagag ggcggctcaa ggcagatacc
     2101 aagggatact tttgttcata ataggcatgt gactgaagag ccactagcac ataatctgta
     2161 gcaaattcgt ccttaacatc aatgacataa gattctactg ccccaacctt aagagcctta
     2221 tcatggatga aatctaagtc tttcccttca cccacatcca tacaaactga aacaacatca
     2281 tagtctttct ttaaccaggt aatagcaact gatgtgtcca aaccgccaga ataggccaaa
     2341 attacttttt ctttactcat gttcttttcc ttctttctat ttttcaatgg atgctttaaa
     2401 ggcatcctca atgagtttgt ctaattcccc agactccttc aacttttgaa tggttttatc
     2461 gactgcctct ttcaattcct tgctatcttt tttcatggct accgcgtagg aatcatcttg
     2521 ctctttttca aaattgaggt ctgcgattgc taaatcagga ttattttcca caaatccctt
     2581 ggaaacaggt tcttcaaaga taacggcatc cacttgtcct gattttaaat ctgtgattaa
     2641 attcccattt ttaggcagag atacgaggga agaattttgt agcaaatctt tcgccatcgt
     2701 ctcttgaatc gaacctttct gcgctccaac ctttttctgc gccaagtcgt ttacagactg
     2761 ataagtagtc aagtcagatt ttttgacaat gagtttattt tttgcagtat agtagggaat
     2821 ggaaaagtca aacaccttgc tccgttcatc tgtcttagaa acacctgata tggcaaggtc
     2881 tgcttttcct gattgaacac tagccagtac attatcaaaa ctcatgggag atagttccaa
     2941 ttcgacacct agttctgttg cgatagcctt ggctaattcg atatctgaac ccacaatctg
     3001 atttttccca tcaaccactt tttgatattc aaatggagca aaatctggat tgagggctac
     3061 aaccaatttt cctttggact tgatggcttc aattccagcc gattgattgt tactacaagc
     3121 aaatagtagg gggagcatca ctaaaccaaa catcgtcatc aacaccttct tcatcttatt
     3181 cataacaaag ccttctttat gtttattctt ttttattgta taaataatac tcctatactc
     3241 atatactcat cctttgtcaa gcctaaattg aaaaaatttt caatttgaaa caaaaaaaaa
     3301 cctagaaatg ctacataaaa tgtcattcct aggcgtattt atgctatttt tctctggaaa
     3361 acatgagtat tcagccagtc aaaaggagct gaatgaactc attttccctc gcccaattca
     3421 atgacacgat gacattgttg ggctacataa gcatcgtggg tcacaataat gactgttttc
     3481 ccttctcgat tcatctctaa gagaaacttc aagaccaaat ctctattttc aggatccagc
     3541 gaacctgtag gttcatcggc taaaatcagc tggctgggtt ttaagatggc tctagcaact
     3601 gcaattcgtt gttgttcgcc cccagacaac tcggagaccc tttgatgcaa agtagctgac
     3661 aaacctactc tctctaaaat ctcttccacc tttttgagct tgtctttctt aggcaatttc
     3721 acatatttca gcgccagcat gagattgtac tcgaccgttt catcatcaat cagggcaaaa
     3781 ttttgaaaca gataagagat atgttcacgg attattgttt gcgacttagc agaattaacc
     3841 gctagatttg tctgaccaaa aatctcatac cgtccgctat aatcaccatc tatcaaaccc
     3901 aataaattta acaaggtcga cttcccacta ccactcttac caacaatagc taccaaatcc
     3961 ccctgatcaa tcctgagaga taagttatcc aaaatcactt ttcccccaat ggttttggta
     4021 atatttttca actcaatcat aagatgcccc ctttcaataa ctctactaga cttcttttct
     4081 ccatcctaga agctaagcct agcacaaata gtatatccag acatgtaaaa cctgcaaaca
     4141 gtagaagtgg taagaacgca tgggcaaaga aaatcaagac tagaagaggg aaactatagc
     4201 ccagcaagag cagaacgagg agaggacggt agcgatcgac cagtttccac cccataaact
     4261 tcttggtaat gatatccctg cgcttcaata agaaagttgt tactagtaag aagtaggaaa
     4321 tcatcatgct aaggagacca aacaaagcaa agagtaggtt aaaattccga acagcatctc
     4381 tataagaatc cactttctct tgttgaatgg cttgaataga tgaaaatttt aaataatttc
     4441 catctgacaa tttctcaact aactctgtaa tctctttttg atgttgaacc gtattttcaa
     4501 ttttaatcgg attatttaag ccagttgttg acagggaggc tttctcatcc cacatcatat
     4561 cagaatcatt gaccaagcta ataattggat tggagagatt ttcctttcgc ttatcactat
     4621 atgggaaaaa tgaccaatct ccttcataat aggcaatctc gacatccatc tcctctatcg
     4681 ttcgtttttg ctgctcttca tacttcatcg aatgaaaggc aattaacttc cccaagagct
     4741 gatttttatc ttcttcacct ttcgtacttg ctggcatcaa aataactttt ttaataccgg
     4801 tatctggtag cttgaatccc ttgctcttta gaaaattgcg attggcatag taaacatcca
     4861 ccgtatctgt taactgatat tgctgaatct gttctgattg gacaaaattt tttacaggaa
     4921 gactgctact ctgcacatag cccgcctgcg ttttttctac caaatcctga taaaatcgat
     4981 agaaataatc tgtagatttc cctgaccctg ctagctcttc ttgccacaga ttatcattga
     5041 gtttgaaggt ttctaaggtc aggtaattac cttgacttac ccactgttgc tgataagcaa
     5101 gttctttgtt ttcttgttct aaacttctgc ccaccccaat cagtaaggcc gtcagtaaaa
     5161 tagttgtccc tattttcatc acataattga agataagacc aaatttgaaa gatgaaaaac
     5221 ctttcagcag agagctgatt gtcatttttt ggattaagag gtaagtcaac caactgataa
     5281 agagataaag ctgcaacagc aaaaaatgag acaaccacag cataggaaac aaatcttttg
     5341 gcttataatc aagcaagaaa aacacgccta gattgatcac aagagcccca cctaggagga
     5401 ggtaaaggtt gccttttaca acatcagcta aaacagccct atcttgaaaa ccaagtaatt
     5461 tttgtacccc aactcttttc atctccatca tcggttgata cactgtcact aacacaagaa
     5521 gcaaaatagc caagacaaaa acaatggcag ataaaagcaa atctcgattt atgacttcca
     5581 ctgcactttt gtaggtcggc tctagcaagg tagcctggtc tatcttgaaa aaatcgctcc
     5641 atttctgtac aatcctatcc ttgtccatct cttgtgtaga agttatcgta tagcgaccat
     5701 ttaaactacg agatgtatcc ttgatatagg tttgaaaagt cataagctga ataggtttgg
     5761 cttttagaaa ggtcggaatc gtaccaagtt tattggaaat ttctttatta ctatagactc
     5821 cttcaccatc tgtggtaaaa tcaagagaag aaatcccaaa ctcttggtag gggaaggtat
     5881 ctttatcaaa aacaccagac ttgaccacct catcaccact gtctgttttg atgatggaga
     5941 ctttatactc ctttgataca tcctcaaaaa atcgaagaac agacgctgca ggttcgttaa
     6001 tatctttcaa atacaaatcc aaagaatcta cagtctttcc catttcttga atccgaacca
     6061 cttctcgtgt atagtttaca ttaaaaacaa aaaaagtggt acacagaagc aggagtaaca
     6121 tacagaaatt actgattttt ttcataaaag tgcctccact acagttttcc ctctccaaat
     6181 aggagaggga agaattttac tcaaatccat agaaatattc cattcctgtt ggcggaatct
     6241 tggtgaggga agctctagcc catgcctcag gttttgcata atccttagag gttctacccc
     6301 catgtctaac agttgctgta tgatatcgag tagaatgtaa gtaatcagaa tatccaaaag
     6361 ttcctgtcca acctactcca tagttccatt gaccaccctc aacccatact gctaaagcat
     6421 ttgtagtagc aagtatacca cataccatta aagatgcaac accaatttta actaattttc
     6481 tcatgattta tttctcctat tatcgagagc tgttccgtaa aaacagctat agtaatttat
     6541 caacaagtat cgtagtccat tggactcacc ttccttctat ctcatttcat tttttaacaa
     6601 cgaacttact cttaaccggg agaatggtgc gcttctgtat caggtccttg aacaaccaga
     6661 gtagtattaa gcacactcta actattactc aagaatcagt ccaataaaca atatggatag
     6721 cgctttcaaa tttttaaact cctatcccat ccttttatct atataataag cgaaaatata
     6781 ataactgtca agtaactgaa gtgaatttta taaaaaaatt acaagccaaa tttgtaaagt
     6841 ttacactaag ccgctagggc aatcgtctat cagaatgtcc gtttatttgt caataatccg
     6901 agaaaatctt gcaacgctta gaagtctata aaaactatca acatttatat gacttgcgaa
     6961 tagcaatcct gctaaacctt tccacactct atctatacaa tcaagataaa aacatgtgta
     7021 agcaaatctg ctacacttta ctggaggacg ccaagaataa gaaaagctac gataggcttg
     7081 ctatctgcta tgtccctatt gggatttgta cagataatgc taaacttatc caaaaaggtt
     7141 tctcacttct ggagctgacc gaggaaactt ctatgctgtc tcatctcaaa aaagaagtag
     7201 agacccatta tcaaccaaag aaattataaa aaaagtcgag ggagctcctc gaccttttac
     7261 atattatttg ttcgttagtt cttaatacca gccattgtta agccagaagt ttttagcagc
     7321 agtccatgaa ccgtaacgtc ctgcaacgta ggcatctgct acacgttctt ggttttcagc
     7381 tgagtagtca ccgttcaggt atgaatctgt taattggtaa cgtccgatat aacgtccatt
     7441 tgtagctgta tagctaccac ctgattcttt ttgagcgatc cattctttgg cttctgcttc
     7501 agatccgctt acagttgaaa caactgtttc acttactact ggagctgaaa cagtttcatc
     7561 ttgagcggct ggtgccgcat aagtagctgg cgctggtgtt gcaacaggcg ctacagggcc
     7621 atcgataacc aactcttgat caacataaat caaatgaatg ttatcaatgt ggttgttttc
     7681 tgccaatttt tcaactgttg tgttgtgagt ttcagcgatt tctgaaagtg tatcaccttc
     7741 tttaacagtg taagttgatg attcttgagc agatacaaat gatggagcaa atactgcaaa
     7801 caaggcagct actcctgcaa gagttgcttt aatcttttta gttattgatt tcatattcga
     7861 aaattctcct tctttctata gttctatcat accctttaaa tattaccgtt tcttgacact
     7921 tttatgtaga aatattacaa aattattttt tatttcccta aataaggtgt tttttgtcat
     7981 aaaagatact atttttatgc tatttgaggt attagaaagg ttttcatcca caattaaagc
     8041 caagcccctc attctttgat ataatagaga taagaatttt tataagggga aactgatgaa
     8101 atcacttcgt tttcaatctg tctttgatat catcggacca gttatgattg gcccatctag
     8161 tagccatacc gctggtgctg ttcgtattgg gaagattgtc tcttccattt ttgatgatac
     8221 tccgacagaa gttgaattcc aactttttaa ctcatttgcc aagacctatc gtggtcacgg
     8281 aacagaccta gcccttgttg caggtatttt aggaatggat acagatgatc ctgaaattcc
     8341 aaatagtctg gaaattgccc acaagcgtgg tatcaagatt gtctggacca ttcagaaaga
     8401 cagcaatgcc cctcacccta acaccactaa aattactgtt aaaaatgccc acaagaccat
     8461 cagcgtgact ggtatttcta tcggtggagg aaatattcag gtaaccgaac tcaatggttt
     8521 tgccgtctct ctcaatatga atacaccgac tatcatcatc gttcatcaag atattccagg
     8581 tatgattgcc cttgttacag aggcgctttc ccgctatggt atcaatatcg cccagatgaa
     8641 tgtcactcgt gaaaaagctg gtgaaaaagc cattatgatt atcgaagttg acagtcgcaa
     8701 ctgtgatgag gctatcgaag aaattcgaaa aatccctcat ctccacaatg tcaatttctt
     8761 taaataggag gaagcatgtt ttattctatc aaagaattgg tcgagcaagc agatctagac
     8821 tttcaaggaa atgtcgcaga actcatgatt acaacagagt ttgaattgac cggtcgcgaa
     8881 cgtgaagaag tcttccttct catggaacgc aatctggaag ttatgaaagc ctctgtccaa
     8941 cttggcctca atgaaaataa atctcgtagt ggcctgacag gtggagatgc tgccaaattg
     9001 gatcactaca tcgaaaacgg aaaaactctg tcagattaca cgattctctc tgctgcccga
     9061 aatgccatcg cagtcaatga acacaatgcc aaaatgggct tggtctgtgc cactccaacc
     9121 gctggaagtg ctggctgtct gccatccgtt ctcactgctg ctattgaaaa attagacctc
     9181 agccacgagc aacaattgga tttcctcttt gctgctggtg cctttggact agtcatcgca
     9241 aacaatgcct ccatctcagg tgctgagggt gggtgtcaag ctgaagttgg ttcagcctct
     9301 gctatgagtg ctgccgcctt gactctggct gcaggtggaa caccttatca ggccagtcaa
     9361 gctattgcct ttgtcattaa aaatatgcta ggcctcatct gtgaccctgt tgcaggtttg
     9421 gtcgaagttc cctgtgtcaa acgtaatgcc atgggagcta gctttgcttt catcgcagca
     9481 gacatggcct tggcaggtat cgaatctaaa atccctgtgg atgaagtgat cgatgccatg
     9541 taccaagtag gagcaagcat gccaactgcc tttcgtgaaa cagctgaagg tggactcgct
     9601 accaccccta ctggtcgtcg cctccaaaaa gaaattttcg gagaataagc ttatcaaata
     9661 ggagaaacca tgacctctat cacagcgatt tttttcgatt tggatggaac cctcgttgat
     9721 agttctatcg ggattcacaa tgcctttacc tataccttta aagagctggg ggtgcctagc
     9781 cctgatgcca aaactattcg tggttttatg ggaccacctc tcgaaagtag ttttgcgacc
     9841 tgcctgtcca aagaccaaat ttctgaagcc gtgcagatat atcgttctta ctataaggca
     9901 aaaggcatct atgaagctca actctttcct cagattatag acttgcttga ggagttatcg
     9961 agcagttatc cactctacat caccacgaca aaggatacat ctactgctca agacatggca
    10021 aaaaacttgg aaatccatca tttctttgat ggcatttatg gttctagccc tgaagcaccc
    10081 cataaggcag atgtcattca ccaagccttg cagacacatc aactagcacc agaacaagcc
    10141 atcatcatcg gagataccaa gtttgatatg ctgggagctc gagaaacagg tattcagaaa
    10201 ttggccatca cttggggatt tggagagcaa gcagatctac taaactatca acctgattat
    10261 atcgctcaca aacccttaga agttttggcg tattttcaat agcatagact gggtaacaat
    10321 tccatttcag aagaaaatga agtaatactc aatgaaaatc aaagagcaaa ctaggaaact
    10381 agctgcgggc tgctcaaaac actgttttga ggttgcagat agaactgacg aagtcagatc
    10441 aaaacactgt tttaaggttg tggatggaac tgacgaagtc agatcaaaac actgttttga
    10501 ggttgcagat agaactgacg aagtcagatc aaaacactgt tttgaggttg tggatagaac
    10561 tgacgaagtc agtaaccata tacggcaagg cgacgttgac gtggtttgaa gagattttcg
    10621 aagagtataa gtctctacat aataaaacgc atattaccaa ggttgtgtaa ctggatacta
    10681 tgcgtttttc ttttttattc aatgtgggtt gtttgattag caaaggcgat aatagcttgc
    10741 ttcaactcat ctccactgag agtgcggaac tctccaatct tttgattgat ggattctaaa
    10801 ggcatgacat taaccttacc aacgaaaatc ttatccataa cttgattatc aacgagttcg
    10861 gttgatacca agagttcttc gtagagtttt tcacctgggc ggattccaac ttcaacgatt
    10921 ggaatttcac tttcagtgtg gccacttaga agcaccatct tcttggccaa gtcataaatc
    10981 ttgactggtt tgcccatatc aaggataaag acttccccat ctttggcata agcaccagca
    11041 tggataacca gacggctagc ttctggaatg gtcataaagt aacgggtcat gcggaagtct
    11101 gtcaccgtta caggcccacc ttcagcaatc tgacgttcaa agactggaat gacactacca
    11161 cggctaccaa gaacattccc aaaacgaact gcacagtagg ttgattggct acgttggtta
    11221 aagccagtga caatcaactc cgccacgcgc ttggttgctc ccataacatt tggtggattg
    11281 actgccttat ctgtcgaaat cataaccatc ttagacactt tagcttcatc aacagcctta
    11341 gcaacattgt aagttccacg gatattgttt ttgaaggctt cttttggatt gcgctccatc
    11401 ataggaacat gcttgtgggc agccgcatga taaacaatag caggtttgta ctgctcaaag
    11461 acttgcaaca aacgatcata gtcttgaatg tccgcaatca caggtacata atcaatccct
    11521 tggaacttac gaatcaattc atgataaaca aggtagattg agttttcccc atgaccgagc
    11581 aagacaatgc gttcaggatt gaagcgacta acttgacgac agatttcaga accgattgaa
    11641 cctccagctc ctgtgactaa gatggtctta cctgtcagtt ctgcacccag acgcgattcg
    11701 tcaagacgga tttcctgacg acccaaaagg tccgtaatat caattttttg gaagccagta
    11761 cctgcttggt gaaggccctg aacaacagtt tcaaccttag gcatcttgta acatttgaca
    11821 cccagcttat tacacatctg caagatacgc tcatattctg acggatccag cgacggaatc
    11881 gcaacgatga cacgctcgat ttgatggcgt ttggctaatt caggcagatt gtcataagag
    11941 cccaaaacag gaataccacc aagtttttga ccctttttct tagaatcctt atccaaaata
    12001 ccgaccagtt ctaattcact ggttggatgt tggtaactat ccataaagag agccccacca
    12061 tcaccggcac caatcaagaa ggttcgacgg tgttctccat caccactacc ttttttgcgt
    12121 ctggagtaga ttaactgcca agtaatccgt ggcaataaaa tcaagaaggt actcaacaag
    12181 ataaagagaa tgatgaaacg gatggagaag agtggcaaga aggcataaca gatactatat
    12241 gacaagacac tgctagcagt cacaccaaaa aagattttca tgaaatccgt aatcttgctg
    12301 taacgactaa tgctcgcgtt caacccccaa aaaccaatca tcaattgata gaacaggaag
    12361 gccaaactcg tatagataat gtagtcaaca ggtgctggat taatcagccc ataaaataaa
    12421 atataagata caatgatgga aaccaccata ctgaaaatat caaatattcc ccagaaaacc
    12481 tgcttttgtt gtttatttaa aatttccacc agatcaatca cataatctgt tagtttttta
    12541 ttcatagaaa tctactcctc cttaaaagag ttttactata ttgttattat agcatatttt
    12601 gatttatttg gcttatttta tccaaataaa ttattgttct cttgtactcc ttcttccatt
    12661 taaatcctct aattaaacct acaatcgtcc caaagccata agcaaagtga atggaaaata
    12721 aaagaaaggg catcacaatt agaaatccat ttttatgttt taataaagtc agcaaagtga
    12781 gtaatgacaa aagtagaaaa taggcaccta atagtaaagt tatgaatacg aatgtgatcg
    12841 gtaacaatgc tagactaaac acaagactca aaacaaataa acaaggaaca tagtgaaata
    12901 atgataaaca cttaaactga acatgacttg tcaagccaat ccacaaacca tttgaatact
    12961 tttgatgcag cattttcttg aatgttggtc gaatatactg ataagataga atacttgggc
    13021 tatagcggat tttataacca tgttctcgaa ttctataatg aatatcatta tcttcagttc
    13081 ggccaagttg ctcatttact aaaccaacct tctggaaaac ctctcgttta tacatcccat
    13141 gaaaaataga agaaacatat ctatcctcgg aactatttcg ataattggca atgctactgc
    13201 caaacatatt ttcctcaaca agatgcaagg tctctgccca ttttcctttt ccttcgacaa
    13261 tcgtcggtct aggcccccca cagacaaatt caccttgttg aataatagcc acattgttca
    13321 ttacaaaact ctcagtaact tttgaatgag catcaatttt taaaataagg tcccctacag
    13381 aatgtttaac tcccaggtta aaaccactag cttgattttt cttaggattg ttatacaatc
    13441 taattgagtt aaactctgta tcttccttta taaattgctg aatgatagct gtggtcccat
    13501 ctgtggacat agcatttata aatagaattt caatatcctc tttaggatag gtttgatttt
    13561 ttaagtcttc aattagacca ggcagatatt tttcttcatt gtatgcactg attacaatgg
    13621 atacgagaag actttcaaca ttttgagtca ctactactct cctgaatttt tccttccacc
    13681 attctatcat aattttcaag actttcccat ttttatcttg aaagccagaa accttacttg
    13741 acattatagt gaaaaagcct taaaataagc tgttattaaa atcagctaga agaggtatta
    13801 tatgaaaaag caatcactct tttttgttcc aggtattatc ctgattggtg tttccttgcg
    13861 aactcctttt actgttttac ccattatttt gggaaatatt tcgcaaggtc tggaggtaga
    13921 agttagttcg cttggtgtct tgaccagcct gcctctcctt atgtttaccc tcttttcacc
    13981 attttctacc caactggctc agaaaatcgg cttggagcat ctcttcacct acagcctctt
    14041 cttcttgacc atcggctcac ttattcgact aatcaatctg cccctgctct atctaggaac
    14101 cttgatggtt ggggcaagtg tcgcagtcat caatgtcctg cttcctagtc ttatccaagc
    14161 caatcaacca aagaaaattg gttttctgac caccttatat gtaacgtcta tggggattgc
    14221 aacggctctg gcttcctatc tagctgtgcc cattacacaa gccagttctt ggaaaggact
    14281 tatccttctc ctcacgttac tctgtctagc aacttttttg gtctggctcc caaatcaccg
    14341 ctataatcat agactagctc cacaaaccaa acaaaaaagt caaataaagg tcatgcgtaa
    14401 taaacaggtt tgggcaatta ttatcttttc aggttttcaa tccttgatct tttacaccgt
    14461 catgacctgg ttacctacca tgtctatcca tgcaggtcta tccagtcacg aagctggctt
    14521 gctgacttct atcttatctc tgattagcat tcctttttca atgaccatcc caagcctgac
    14581 aaccagttta tctactcgca accgtcagct catgctcact ctggtttcac tagctggtgt
    14641 ggtcggcatt tccatgctct ttttcccaat caataatttc atttactggc ttgccatcca
    14701 tctcctcatc ggaaccgcaa ccagtgccct cttcccttat ctcatggtca acttttcact
    14761 caagacaagc gcccctgaaa agacagccca attgtccggc ctatctcaaa caggaggcta
    14821 tatcctagca gcctttgggc caaccctctt tggttacagt tttgacctgt tccactcttg
    14881 ggtaccatct gtagctgccc tcttgctcat cgatatcctg atgactgtgg ccctctttac
    14941 agtggacaga gcggataaga tcctttaaac ttctagtttt agctagaagt tttttatata
    15001 taaaaatttt acacatttct cttgacaggg ctttctttta gatgtacaat gtatgtgtag
    15061 aaaaattata tataaaaatc ttacacatta gaaaaggagg tttcccatgt actttccaac
    15121 atcctctgcc ttgattgaat ttctcatctt ggctgtactg gagcagggtg attcttatgg
    15181 ttatgagatt agccaaacca ttaagctgat cgctaatatc aaagaatcca cactctatcc
    15241 cattctcaaa aaattggaag gcaatagctt tctgacaacc tactctagag agttccaagg
    15301 tcgcatgcgc aaatactact ccttgacaaa cggtggtata gagcagctct tgaccctaaa
    15361 agatgaatgg gcactctata cagacaccat caatggcatc atagaaggga gtatccgcca
    15421 tgacaagaac tgaatacctg actcagctag aactctatct caagaaacta cctgaagctg
    15481 accgtatcga agccatggac tatttcagag agctctttga cgatgctgga gtcgaaggag
    15541 aagaagaact catcgctagt ttgggaactc ccaaagaagc ggcccacgaa gttctatcca
    15601 atcttctcga taaaaaaatc aatgaagcac ccgctcaaaa aaataaccga caaattttac
    15661 atatcgcctt gttagccctc cttgcagcac ctatcggcat tcctctggga atcgccatcc
    15721 tcgtgaccct gttcgcaatt cttgtagccg ctttgactgt cattctggct ttctttgcag
    15781 tttccatact gggtatcatc ggcggattcc tatttttagt tgaaagtttc actgtcctcg
    15841 cccaagccaa atcagccttt atcttgattt ttggttctgg tttactggct atcggtgctt
    15901 cttcgctagt tttacttggc atttcctatg caactcgctt cttcggtcta ctcattgttc
    15961 gtctggtaca atttgttctt aaaaaaggaa agagaggtaa tcagcatgcg taaatggaca
    16021 aaaggatttc tcatctttgg tgtggtgact accgttatcg gctttatcct gctttttgta
    16081 ggtatccaat ctgacgggat taagagccta ctttccatgt ccaaagaacc tgtctatgat
    16141 agccgtacgg aaaagctaac ctttggcaag gaagtcgaaa acctagaaat tactctccac
    16201 caacacacgc tcaccatcac agactctttc gatgatcaaa tccacatttc ttaccatcca
    16261 tctctttctg ctcaccatga tcttatcacc aatcagaacg atagaactct gagtctcact
    16321 gataagaaac tgtctgaaac tccgtttctc tcttctggaa ttggtgggat tcttcatatc
    16381 gcaagtagct actctagtcg ttttgaagaa gttattctcc gactaccaaa agggagaact
    16441 ctaaaaggga tcaacatctc agccaatcgc ggacaaacca ccatcataaa tgctagcctt
    16501 gaaaatgcga ccctcaatac aaacagctat atcctccgaa ttgaaggaag tcgtatcaaa
    16561 aacagtaaac tcacaacgcc caatatcgtt aatatctttg atacagttct tacagatagt
    16621 cagctagagt caacagagaa tcacttccac gctgaaaata tccaagtcca tggcaaggtt
    16681 gaactgactg ccaaagatta tctcagaatc atcctagacc agaaagaaag ccaacgaatt
    16741 aactgggaca tctcaagcaa ctatggttct atcttccaat tcacaagaga aaagcctgaa
    16801 tcaagaggta cggaattaag caacccttac aaaactgaaa aaaccgatgt caaggatcaa
    16861 ctcattgcga gatctgatga taatattgat ctaatatcca caccaagcag acgttgacaa
    16921 aaacgcttac atttgctact atggaaacat atttatctaa ctaaaaagga ggttctacca
    16981 tgaaacaaga atggtttgaa agtaatgatt ttgtaaaaac aacaagcaag aacaagcctg
    17041 aagagcaagc tcaagaggtt gcagacaagg ctgaagaaac gatagccgat ctcgatacac
    17101 caattgaaaa aaatactcag ttagaggagg aagtccctca agctgaagtc gaattggaaa
    17161 gccagcaaga agagaaaatt gaagctcctg aagacagtga agcgagaaca gaaatagaag
    17221 aaaagaaggc atctaattct actgaagaag agccagacct ttctaaagaa acagaaaaag
    17281 tcactatagc tgaagagagc caagaagctc ttcctcagca aaaagcaacc acgaaagagc
    17341 cacttcttat cagtaaatct ttagaaagtc cttatatccc cgaccaagct ccaaaatcta
    17401 gggataaatg gaaagagcaa gtgcttgatt tttggtcttg gctagtggaa gcgatcaaat
    17461 ctcctacaag taagttggaa acaagtatca cacacagtta cacagccttt ctcttgctca
    17521 ttctgttttc tgcatcttcc tttttcttta gtatctatca catcaaacat gcttactatg
    17581 gacatatagc aagcattaac agtcgcttcc ctgagcagct agctccttta actctttttt
    17641 ctatcatctc tatcctagta gcgacaacac tcttcttctt ttcattcctc ttgggtagtt
    17701 tcgttgtgag acgatttatc caccaggaaa aggactggac gctagacaag gttctccaac
    17761 aatatagtca actcttggca attccaatct tcctcactgc tattgctagt ttctttgctt
    17821 tctttgatag cctacgattt acagccctct tgtgtgtgat tagcattgga atcattctgc
    17881 ttgccagtct ccatatcatt acaagaccaa gtcaagcaag tgaaaccgac tccttctatc
    17941 aattattctt gtctgtcctt gtgaacggag ttattatcct cctcttcttt gtagctgaag
    18001 tggcactgat tggagattat cttcgtatct tggcctttct ttaaacttca tactcttcaa
    18061 aaatcaaatt caaaccacgt cagcttcgcc ttaccgtact caagtacagc ctgcggctag
    18121 cttcctagtt tgctctttga ttttcattga gtagcaatcc tgtcatcctt ggcaggattt
    18181 tttctatgtc aaaaaagcaa gtcgattgac ctgcttctgc tttacttttc ttgtgctaat
    18241 gttttaaaat ctttgtctaa tatgggttgc acttctattt gattggcgtc tagttggtgg
    18301 taaaaagatg ggggtaatac ctctaagaat tttgcatagt ccaagcgagc aatggcttca
    18361 tagtcttctg gtttagagcc atctcctgtg atttgaacca agtcaatctc ccactggact
    18421 tccttatcca ccaattgctc aatataggct gcaggaacaa acggttctct cggtaaaact
    18481 gtcttgactc cttgagctag atggtaaacg ccatgcactt ttccttctcc atcctgatag
    18541 aaggaaactc tctcaaagta ggcatctgtc tcttgaaccg cacgcacacg cgcttcaaac
    18601 tgagccaagc catctgcctc taaaaagctt ttcaagttct cacgactaaa gaaaatagga
    18661 ttaaaaattc cttggcaaat cgtaaaacga gctacagggt ctgctagata ggcttgaata
    18721 cttgcttgga aataagcttc aaaatcaaaa ccatctagcc cttcaatatc agtccctgta
    18781 taagcaagca aagcatctaa aaatgacttg ataatctgcc agtctgtctt tgttagtagg
    18841 tcaggaagat cgacacggta agccttttga ccatcagcat aactgacctt aaagagaaat
    18901 tgtgattgcc ccactatcgc acactcgata tattcgagac gattaagagg ctgacggaga
    18961 tagactacat catagctatg tgactccaaa ccgtctagca aggccaagat cgacttggca
    19021 ttcaaaatct cttgttctcc taaaatgctc tgtttatttg gaataaaaaa tgttttcgcc
    19081 ataactggac tcctttgaaa tcgtttacat acagtatacc ttatttttct gaaagataca
    19141 aaaacaaact ttatactctt cgaaaatctc ttcaaaccgc gtcagcttcg ccttgccgta
    19201 gatatatgta actgacttcg tcagtcttat ctacaacctc aaagcagtgc tttgagcagc
    19261 ctgcagctag cttcctagtt tgctctttga ttttcattga gtattagatt tttgagtaca
    19321 aagcatagaa aaacagcccc taaggactgt ttgatcttat acagtagctg cctgatccaa
    19381 gctttcaccg atagcggcta ggcgctcaat cacttcagct tgtgtcaatt cattttttga
    19441 aacatagcgg ttacgtgggt gaacacggca ctcgtgtgag catccacgaa ggtacttgtc
    19501 ttcattttct tctgatgtca agatacgacg gttacagaag ggatttccac agttgacata
    19561 acgttcacat ggtgttccat caaaccagtc tttccctacg atagttgggt tgacatggtt
    19621 gacatcaacg gcaatacgct cgtcaaagac gtacattttc ccatcccaaa gctcaccttg
    19681 aacttctggg tctttaccgt aagttgcgat tcctccgtgc aattggccga catctttgta
    19741 gccttcacgg accatccagc ctgagaattt ctcacagcga acgccacctg tacagtaaac
    19801 cacgacacgc ttgtccatga atttttcctt gttatcacgg acccattgtg gtaactcacg
    19861 gaagttgcga atatctgggc gaatagcccc acggaaatgt cctaggtcgt actcataatc
    19921 gttacgtgtg tcaaggacaa cggtatcttt atcaagaagc gcttctttga actcttttgg
    19981 agacaagtaa gcacctgttg tttcaagtgg gttgatgtca ttgtcaaagt cgttgtcttc
    20041 caaaccaagg tggacaattt ctttcttgta gcgaacaaac atcttcttga aggcttgttc
    20101 tctttcttcg tcaatcttga accagagatc ttccatacct gggaggctgt gaacgtagtc
    20161 catgtatttt tgagttgttt catagtcacc tgaaactgtt ccgttaattc cctcgtcagc
    20221 gactaggata cggcctttaa ggccgattga tttacagaaa gccaagtggt ctgcagcaaa
    20281 ttgctctgca ttttcaattg gagtataaag gtagtaaagt aagacacgaa tatcttttgc
    20341 cataagattt gttctctttt ctattcttaa attttctaaa ttttttattt atccatacta
    20401 gtatacctgc ttgagaaaac gaatgcaatt tatttgactg gaaattgtag agggttctcg
    20461 aaatttcctg aatggttaaa ataaggacaa gagaaaacat ggatatctat atccttgtgc
    20521 caaaaaaacc actgccctcc ccagaccaac ctgaggaaag cagtgattct tattttagga
    20581 gttaggaatg aatacacgaa atcaatttag ctgattattt tttgtttttc aagaattcat
    20641 cgtattgttt ttgcatttcg ttcaatactt tttcgtaggc accttcagat ttcaattttt
    20701 ccatcaattc tggaatagct ttatctgggt ctacagtacc agtgttgata gctgtatcaa
    20761 attgttgcat tgtgttagca atagctgaga tttcagattt cacattgtca gtattgaaga
    20821 taaatccaag cgctggagat tctttagctt ctgccaattc tttcttagaa ttttcgattt
    20881 gttggtctgt aacgttttcg ttgatgtaaa ggatccagtt gttaccagtg ttccatccac
    20941 ccatgtgagt gtttcctttg tagccatcaa gaacgcgaac acggttttct ttaccttcaa
    21001 ttttttccca gttcttgcct tctggaccgt aaacaagacc gttcaagagt tctggattcg
    21061 tattcaagag gttcaagatt tccattgatt tttctttgtt cttagagttg tttgagatga
    21121 caaagttagc aacttgtgtt gtttggtttt tcttgatgaa gttagtaatt ggtttgattt
    21181 ggatatcttt gttggcaaca cgtgaaagca agctgttacc gtagtcagct ggtcctactg
    21241 tttcttcacg aacgaaccaa gtatcttgtt gaaggtcaaa ggaagtatcg cttgttgcga
    21301 catcttttgg aatgtagcca gcttcataga atttgtgaag agtcttcaag tgttctttga
    21361 aacgaggcac ttcgtaacgg tttacaactt tagtagtatc gccttcaagg tcaataacga
    21421 atggaagccc gtttgctact gggtagtcaa aattatcaga tgggatgaaa actttaccaa
    21481 tagcaaatgg tactacgtct ggagcttttt ctttgatttg tttcaagact ggctcaagag
    21541 tttcgtaaga agtaacacct gaaatatcga taccatattt ggcaaggaga gttccgttga
    21601 aggcaaagtt ttgagatgat gctacgttgg ctgcaactgg tacagcataa atcttaccat
    21661 ttacagtatt acccttgata taagctggat caagtgcctt gtaaaggtct ttaccttctt
    21721 ttttgtacaa ttctgtcaag tcagcataag cacctttttg agcatttaca atatagttat
    21781 ctgcaaaggc gatatcatag ttttcaccag atgatgtgat aactgacatt ttcttaccat
    21841 agtcacccca gccaaggtat tggatatcca atttggcacc aactttttct tcgatgattt
    21901 tgttggcatt tgctaacaat tcatccaagt tatctggttt gtcaccgatt tggtacattt
    21961 tgataacagg tttgtcacct gaatcagcag cttttttact gttacctgtc aagttgccac
    22021 aagcagcaag acctgcagcc aaagcgacta cactagcaga tgcaaaagca tattttttcc
    22081 agtttttcat gataaaaact ccttttttta tttttaaact tataaacaat gtaatgatct
    22141 tatactcaat gaaaatcaaa gagcaaacta gaaaactagc cgcaggctgt acttgagtac
    22201 ggcaaggcga cgttgacgcg gtttgaattt gattttcgaa gagtattaac ttcacacaag
    22261 ggaagttggg aactgagaaa tgttatttct caataagcac tattctttca caccaccgat
    22321 agtcaaacct tttacaaagt agcgttggaa aaatggatac aaaatcgcga ttggaagggt
    22381 tgcaaccaca accatggcca tacgacctgt ttctttcggt agagcaactc ccagttgacc
    22441 agtcaagccg accgctttgg caatgtagtc catattttgt tggatttgca tgagcaaata
    22501 ttgcaatgga tacaagttgt cactcttgat gtaaagaagg gcgttgaacc agtcattcca
    22561 gaaaccaaga gctgttaaga gcgtgatggt tgcgatacct ggtagtgaca atggcaaaca
    22621 gatttggaag aaaatccggg cttcactggc accatcgata cgagccgatt ctagaatggc
    22681 ttctggaatg gtcttcttga agaaggaacg catcaagatg atgttaaatg gtgagagaag
    22741 cattggaaca atcaaggccc aaacagtatc cccaagctga agcacacgag tcaccatgat
    22801 ataacctggt accaaaccag cgttgaacaa catactgagc agaacgaaga tggtaaagaa
    22861 tctgcgatac ttaaaggttg tccgtgaaat agcgtaggca taggttgttg tgataaagac
    22921 atttgtcaat gtcccaacta cggttacaaa gacagagatg aagagggctt gtaggatttt
    22981 atccttaaac tgtgccaaaa actcaaaacc gtctaagcca aattgggatg ggaagaagct
    23041 atagccgtat tggaggaggc ttttctcgtc tgtcactgaa ataatgataa cgaatacaaa
    23101 aggtaggata caagagaggg caatcaaacc cgaaatgata ctgaagaaga tatctgcttt
    23161 cttactgaag gagtgaatgc cgacattatc aattttttct tttttaattt tcttttttgc
    23221 catattctcc tcctttctag aacaaagctg agtttggatc gactcgtctt gcaagcaagt
    23281 ttgataggat aaccagaatc aaaccaacaa cggattggta aagaccggct gctgcagcca
    23341 taccgatatc tgctgtctga gtcaaaccat taaagacata tacgtccaaa acgttggtta
    23401 cattgtaaag ctgaccagca ttgtgtggga tttgatagaa gagaccaaag tctgcgcgga
    23461 agatatttcc gactgcaagg atggtcaata cagttacaag cggagtcaac tgaggaatgg
    23521 ttacgttgcg aatacgttgc cacttgctag ctccgtccac tgtcgctgct tcgtagtagg
    23581 ttggatcaat tcccatgatc gtcgcatagt acatgacact gctatatcca aagcctttcc
    23641 aaatacctag gaaaagtagg agatagggcc agatgcccag gtcagcgtaa aaattgactt
    23701 ctttgagacc aagactttcc aatagatgat tgaacacccc tttatcaata tttaggaagg
    23761 catctgtaaa gaaactgatg ataacccaag acaagaagta agggaacaac atagaagttt
    23821 ggaaaatctt caccattctc ttagaacgga gctcgctgag gataatggca atccctacag
    23881 atacaactaa acctagaaag ataaagccaa gattgtagag gacagtattt cgtgtgataa
    23941 taaaggcgtc tcttgaacta aataagaatc tgaaattatc gagtccgacc catttactat
    24001 ttatgatact atctatgaaa ccattactgg tcatgtggta gtctttgaag gcaaccacgt
    24061 tcccaaatac tggaatgtaa aagaatagaa tcaaccagag tgtccctggc aaaaccatca
    24121 agagaaagat ccagttgtct ctcaatgttt ttgaaaactt tttcataatt tcctcccttt
    24181 ttattttgat atccatctaa aaattctttt ttagactttt gataacgatt acattattag
    24241 tatactccta tttgcaggtt aggttaaact cctaattata gaaaaaactc cacaaattat
    24301 gtagcagatt taaaacttta tcaccactat caaacaaatg tcctaaatca attgtttatt
    24361 ttatctctat tagcccagtg atggcgtcac tctgttataa gcatccaaca acggggtata
    24421 ctgaaaaatc tccagactag ggaactcaga gatagttcct aatctggaga tttttaatat
    24481 gttattaggc gtttgctttc aacttagcaa taacctcttt aagattatca atcacctctg
    24541 cttcagtatg ctcagagctt tttcatctgc caagaacaaa actgcttttt gaagttcttt
    24601 ttgagagttt tcaaggacat ccttatctac tgtttcaagg tttgagtctt taagaagttt
    24661 acttaattcc ttggctaatt tcttgagttt gatttgcaga ctcatcttct cctgctgttt
    24721 ctttgcccgc tgtttgtcct ccatccttag ttgctgactg gctttcctta atggactcta
    24781 gggaagcaat ggcatctttg actgtttgca aaatatcacg taaaccttgc tctgtcaaac
    24841 tatcatctgc aaaagctttc ttagcctctg ccaaaaccag acgtgctgaa tctgtggtag
    24901 gattcgatac acctgtcaat gatctcaaaa gattttctaa ggtttgagtc tgcttactaa
    24961 tactagacta aaatcaaaaa gcattatata acagtgatat gaaatcaact aaagaagaaa
    25021 tccaaactat caaaacactt ttaaaagact ctcgtacagc taaatatcat aaacgccttc
    25081 aaatcgttct atagtaaaat gaaacaagaa caggacaaat cgatcaggac agtcaaatcg
    25141 atttctaaca atgttttaga agtagatgtg tactattcta gtttcaatcc attatatttc
    25201 gtctgatggg caaatcttaa taaagagatt atagagcttt tatagtgatt tgaaataaga
    25261 tgtgaacaac tctatcagga aagtcaaatt aatttataga aatattttag cagccaaggt
    25321 gtactgttat aaattcaata cact
//
LOCUS       DAVKMJ010000030        25328 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000030 DAVKMJ010000000
VERSION     DAVKMJ010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25328
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.030"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(110..313)
                     /gene="blpN"
                     /locus_tag="VW348_001393"
     CDS             complement(110..313)
                     /gene="blpN"
                     /locus_tag="VW348_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEU9746281.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGKILGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(329..583)
                     /gene="blpM"
                     /locus_tag="VW348_001394"
     CDS             complement(329..583)
                     /gene="blpM"
                     /locus_tag="VW348_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEU9746282.1"
                     /translation="MNTKMMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            863..2988
                     /gene="blpA"
                     /locus_tag="VW348_001395"
                     /pseudo
     CDS             863..2988
                     /gene="blpA"
                     /locus_tag="VW348_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
     gene            2999..4360
                     /locus_tag="VW348_001396"
     CDS             2999..4360
                     /locus_tag="VW348_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEU9746283.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVISSIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGIFKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDAIVNKRARLPTGNPHQSILNRY
                     LIASQEQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            4417..4572
                     /gene="blpC"
                     /locus_tag="VW348_001397"
     CDS             4417..4572
                     /gene="blpC"
                     /locus_tag="VW348_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEU9746284.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FHQPIQL"
     gene            complement(4616..5956)
                     /locus_tag="VW348_001398"
     CDS             complement(4616..5956)
                     /locus_tag="VW348_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9746285.1"
                     /translation="MNIAWILLYTLVTNGLEIVIFFKVDGIDLTFERIFKAFLLKFLL
                     GIIFTTFQFLAVSKYLSYFIEPLFGIGLSFLLLRGLPKKILIFYGLFPMILVELFYRG
                     VSYFVLPFLGQGIVDGDGNPIFLLIMIFVCFIVLVFLKWLDYDFTRLRREFLDTGFQK
                     SLTKINWAMGAYYLVMQSLSYLEYEQGIQSTTVRHLILVFYLLFFMGGIKKLDTYLKE
                     KLQEELNQEQTLRYRDMERYSRHIEELYKEIRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLRDSSQKLQDNKYDLGRLVNVRDRALKSLLAGKFIKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTVVSILCDNAIEASVEACQPHVSIAFFKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(5970..6707)
                     /locus_tag="VW348_001399"
     CDS             complement(5970..6707)
                     /locus_tag="VW348_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9746286.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRAHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINKLH"
     gene            complement(6712..7050)
                     /locus_tag="VW348_001400"
     CDS             complement(6712..7050)
                     /locus_tag="VW348_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9746287.1"
                     /translation="MKYMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            7326..7655
                     /locus_tag="VW348_001401"
     CDS             7326..7655
                     /locus_tag="VW348_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEU9746288.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(7823..8872)
                     /locus_tag="VW348_001402"
     CDS             complement(7823..8872)
                     /locus_tag="VW348_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9746289.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(8869..9600)
                     /locus_tag="VW348_001403"
     CDS             complement(8869..9600)
                     /locus_tag="VW348_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9746290.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            9668..10078
                     /locus_tag="VW348_001404"
     CDS             9668..10078
                     /locus_tag="VW348_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEU9746291.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            10088..10375
                     /locus_tag="VW348_001405"
     CDS             10088..10375
                     /locus_tag="VW348_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746292.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            10537..10776
                     /locus_tag="VW348_001406"
     CDS             10537..10776
                     /locus_tag="VW348_001406"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746293.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(11098..12234)
                     /gene="dnaJ"
                     /locus_tag="VW348_001407"
     CDS             complement(11098..12234)
                     /gene="dnaJ"
                     /locus_tag="VW348_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEU9746294.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFATAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(12439..12693)
                     /locus_tag="VW348_001408"
     CDS             complement(12439..12693)
                     /locus_tag="VW348_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746295.1"
                     /translation="MLVTVERNGNVIYKEFTEVAVGKSKYDHTSVFKDVMIYFSDHIC
                     QELHLYKTQDPHYNKFEFDLAKRSLKITTRDNTTIFISNE"
     gene            complement(12806..14629)
                     /gene="dnaK"
                     /locus_tag="VW348_001409"
     CDS             complement(12806..14629)
                     /gene="dnaK"
                     /locus_tag="VW348_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEU9746296.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(15109..15633)
                     /gene="grpE"
                     /locus_tag="VW348_001410"
     CDS             complement(15109..15633)
                     /gene="grpE"
                     /locus_tag="VW348_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEU9746297.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LAMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(15660..16694)
                     /gene="hrcA"
                     /locus_tag="VW348_001411"
     CDS             complement(15660..16694)
                     /gene="hrcA"
                     /locus_tag="VW348_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEU9746298.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(16858..17295)
                     /locus_tag="VW348_001412"
     CDS             complement(16858..17295)
                     /locus_tag="VW348_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEU9746299.1"
                     /translation="MHLKGWRYRTSRFGLFYFDQCQPDDVIYRIYDSRFLKKYKHELQ
                     DFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMSKGLKWEVMRSRLRSCTTTFLGGLV
                     VCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFRLKRKYRVDE"
     gene            17975..20308
                     /locus_tag="VW348_001413"
     CDS             17975..20308
                     /locus_tag="VW348_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU9746300.1"
                     /translation="MVEFIKSKKEMSEEDIKANFITPAIVSKGWKNGEHIAYEEYFTD
                     GRIEVRGDKARRKEGKKSDYSLYYQFGTRIAIVEAKDNKHSVRAGLQQAIEYGEILDV
                     PFVYSSNGDGFIEHDRITREERELELDEFPTREELFSRMTKEKGLTYEITEAISTPYY
                     TDAFSMKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLA
                     KRVLFLADRNILVDQTMAEDFRPFEKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGE
                     DGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGMTATPKETKN
                     ASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKVDANGQLIED
                     RYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQNNARFDKTIVFCVDIDHAERMRAALVK
                     ENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRL
                     IVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLE
                     TGAKTVSGSTPGFVSEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLITESLTDYTRK
                     NILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQEIDDFDLLLK
                     LAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGELESIETLKLP
                     EFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            20321..21784
                     /locus_tag="VW348_001414"
     CDS             20321..21784
                     /locus_tag="VW348_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEU9746301.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFKDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            21784..23352
                     /locus_tag="VW348_001415"
     CDS             21784..23352
                     /locus_tag="VW348_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9746302.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLPPLSEQQRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKK
                     SILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNS
                     YYEEVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLAR
                     FIDPKTVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYGWAVADSHVTVIRV
                     LSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIPLPPLPEQSRIV
                     DKIEQFFAHIDALI"
     gene            23409..24206
                     /gene="psrA"
                     /locus_tag="VW348_001416"
     CDS             23409..24206
                     /gene="psrA"
                     /locus_tag="VW348_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEU9746303.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            24217..24816
                     /locus_tag="VW348_001417"
     CDS             24217..24816
                     /locus_tag="VW348_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9746304.1"
                     /translation="MVKLTTCYFCDYGSYYGNIPMNWVVIKIKDIFSMNTGLSYKKGD
                     LSINNKGVRIIRGGNIKPLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHI
                     GKFARIDKDYDGVVAGGFIFQLTPFESSEIISKFLLFNLSSPLFYKQLKALTKLSGQA
                     LYNIPKTTLSELLIPLAPFEEQELITQKVEKLFEKVNQL"
     gene            complement(24770..>25328)
                     /locus_tag="VW348_001418"
     CDS             complement(24770..>25328)
                     /locus_tag="VW348_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9746305.1"
                     /translation="NKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPI
                     SNHEEMKRIIFKVDLLFQKVSQLFE"
BASE COUNT         8154 a         4972 c         4622 g         7580 t
ORIGIN      
        1 tagtcttttg ttttttatca gagatactta tggatagata aataagatag gtttgaaaag
       61 cgaagagaat aataaagaat atagccttca taaaatttag ctttcatttt tatgatgtag
      121 cggtataggc taaatatcca caaaccactg ctcctccaat tcctcctatt gcagcgcccc
      181 atggtcctag aattttccca tatttcactc cacccgctgc acaacctaaa gcagcaacta
      241 cagctgctcc tccggaatta cctccataaa cctcactcag cattgtttca tttatattac
      301 aataagtatt catacaagtc tccttttatt aaaatccacc cgttgcccct gttactcctg
      361 cccaaagatc cacaccaaat ttagctccta tgtatccaca tgctcccata aatggtgctc
      421 caacaccact cgcagcacaa atagctgtcc ctagccccca gccaccaaaa gcagcaccac
      481 caccttctaa gacattagtt tgccaattat tcttgcctcc ttcaatacta gataacatag
      541 ttatatccat ttcatgaaat tgttccatca tttttgtatt catgacaaat actctttttt
      601 atttttaatt tttgtcttgt tgtaactttg acaagtttag tatatcatcg ttttttaaaa
      661 tttttcatcc agatcttgaa tagtcatcga aacgtcttga attagctttt catttgaaac
      721 cacctctaaa ttttttaaaa aaagataatt tctaattatt ttttaccatt caggaagttt
      781 caatgactat tcaagattta ataaaatatg aacttatttt tatggcataa tatacctatc
      841 tactatatga aaggaattgc caatgacttc ttataaacgt acatttgttc ctcaaataga
      901 tgcgagagac tgcggtgttg ctgccttagc ctcgattgct aaattctatg gttcagattt
      961 ttctctagct cacttgagag aacttgcaaa gaccaataaa gaagggacga ctgctcttgg
     1021 cattgtaaaa gccgctgatg aaatgggctt tgaaacaaga cctgttcaag cagataaaac
     1081 gctctttgac atgagtgatg tcccctatcc atttatcgtt cacgttaaca aagaaggaaa
     1141 actccaacat tactatgttg tctatcaaac aaagaaagac tatctgatta ttggtgatcc
     1201 tgacccttct gtaaaaatca ctaaaatgtc aaaagaacgc tttttctctg aatggactgg
     1261 agtagctatt tttctagctc ccaaacccag ctatcaaccc cataaagata aaaagaatgg
     1321 tctactaagc ttccttcctc tgattttcaa acaaaaatct ctcattgctt acattgttct
     1381 ctcaagctta ttggtcacta ttatcaatat cggtggttct tattatctcc aaggaatctt
     1441 agatgaatac atcccaaatc agatgaaatc aactttagga atcatctcag ttggtctggt
     1501 tatcacctat atcctccaac aagtcatgag cttctccaga gattaagcat tgatgtgatt
     1561 ttatcctata ttcgccatat ttttgaactt cccatgtctt tctttgcgac acgtcgtaca
     1621 ggagaaatca tttcacggtt cacagatgct aactctatta tagatgcctt ggcttctacc
     1681 attctttctc tttttctgga tgtttctatt ctgattcttg tagggggcgt cttactggca
     1741 caaaacccta atctcttcct cctttctctt ctttccattc ctatatacat gttcatcatc
     1801 ttttctttta tgaaaccttt cgaaaaaatg aaccatgatg tcatgcaaag taattctatg
     1861 gttagctctg ccattatcga agatatcaac gggattgaaa ctataaagtc gctcacgagt
     1921 gaagaaaatc gctatcaaaa tatagacagc gaatttgtag attatttgga aaaatccttt
     1981 aagctcagta aatattctat tttacaaacg agtttaaagc agggaacaaa attagttctg
     2041 aatatcctta tcctatggtt tggcgctcaa ttagtcatgt caagtaaaat ttctatcggt
     2101 cagctgatta cctttaacac acttttttct tactttacaa ctcctatgga aaatattatc
     2161 aacctccaaa ccaaactcca atctgcgaag gtcgctaata accgtttgaa cgaagtctat
     2221 ctagtcgaat ctgaatttca agttcaagaa aaccctgttc attcacattt tttgatgggc
     2281 gatattgaat ttgatgacct ttcttataag tatggttttg gacgagatac cttaacagat
     2341 attaatctca cgattaaaca aggagataag gttagcctag ttggagttag tggttctggt
     2401 aaaacaactt tagccaaaat gattgtcaat ttctttgaac cctacaaagg gcatatttcc
     2461 atcaatcatc aggatattaa aaacattgat aaaaaagtct tgcgccgtca tattaattac
     2521 ctaccccaac aagcctatat ctttaatggc tctattttgg aaaacttaac cttgggcggt
     2581 aatcatatga ttagtcaaga agatattcta aaagcttgtg aagtagctga aatccgtcaa
     2641 gacattgaaa gaatgcctat gggctatcaa actcagctct ctgatggagc tggtctatca
     2701 ggaggacaga agcaacgaat cgctctcgct cgtgctcttt taactaaatc tcctgtttta
     2761 atactagatg aagctactag cggtcttgat gtcttgactg agaaaaaagt tatagataat
     2821 cttatgtccc taactgataa aaccattctc tttgtagccc atcgtctcag tatagccgaa
     2881 cgaaccaacc gtgtcattgt tcttgaccag gggaaaatca ttgaagttgg tagccaccaa
     2941 gagttaatgc aggcgcaagg tttctaccat catctattca ataaataagg agaatgtcat
     3001 gaatcctaat ctttttagaa gcgtcgagtt ttatcagaga cgttaccata actatgcgac
     3061 agtgttaatt atacctcttt cattactatt tactttcatc ttgattttct cccttgttgc
     3121 cacaaaagaa attactgtca cttcccaagg agaaatcgcc cctacaagtg tcatttcatc
     3181 tattcagtca accagtgata atcctatcct tgctaatcat ttagtggcaa atcaagtagt
     3241 tgaaaaaggg gacttactca tcaaatactc tgaaacaatg gaagaaagtc agaaaactgc
     3301 cttagcaact caattacaaa gacttgagaa gcaaaaagaa ggacttggaa ttttcaaaca
     3361 aagcttagaa aaagcgactg atcttttttc tggcgaggat gaatttggct accataatac
     3421 ctttatgaat tttactaaac aatcccatga tattgaactg ggtatctcaa agactaacac
     3481 tgaagtttca aatcaagcta atcttaccaa tagcagttca tcagccatcg aacaagaaat
     3541 tacaaaagtt caacaacaaa ttggagaata tcaagagctg agagatgcta tcgtaaataa
     3601 aagagctcgc ttaccaactg gcaatccgca ccagtcaatt ttaaatcgtt atcttatagc
     3661 ctctcaagaa caaacacaag gaacggcaga ggagccattt ttatctcaaa ttaatcaaag
     3721 tattgcaggt ctggaatcat ctatcgcaag cctcaaaatt cagcaagctg gtatcggaag
     3781 tgtagcaact tatgataata gtttagcaac caaaattgaa gtactccgca ctcagttttt
     3841 acaaacagcc tcacagcaac aactaaccgt ggagaatcaa ttaacagaat taaaagtaca
     3901 actagatcaa gcgacacagc gcttagaaaa taatacctta accgctccaa gtaaaggtat
     3961 cgttcatctg aacagcgaat ttgaaggtaa aaatagaatt ccaactggta cagaaattgc
     4021 tcaaatattc cctgtcatca cagatacaag agaagtacta atcacttact acgtatcttc
     4081 tgactatcta cctctactag ataaaggaca aactgtaaga ttaaaactgg agaagattgg
     4141 aaatcacggc accaccatca tcggccaact tcagacaatt gatcaaactc ctaccagaac
     4201 agagcaagga aatctcttta aattaaccgc tcttgcaaaa ctatctaacg aggatagtaa
     4261 actcatccaa tatggcttac aaggtcgcgt cactagtgta actacaaaga aaacatattt
     4321 tgattatttc aaagataaaa ttttaaccca ttctgattaa ttttcagata acactctata
     4381 actatttatt atcttatcaa aaaggagaat cataacatgg ataagaaaca aaacctaact
     4441 tcatttcaag aactaacaac taccgaactc aaccaaatta taggtggagg atggtgggaa
     4501 gatttcttat atagatttaa tataattgaa caaaaaaata caaaaggatt tcatcagcca
     4561 atacaactat aaaaaaacaa gaccaagaga acgcactctc ggtcttattt tttcttcatt
     4621 ctatatgtat tacagtaagt acctgacgaa aaacgtgatc ttggcaggtg gtattgagac
     4681 tggtattggg atgactttcc acaattttca taacggtata gagaccaact cctctctcct
     4741 cccctttaga acttgctcca aaggagaaga tttcagaaat atcgattccc tcttctttga
     4801 tggaattttc aatgataaag gtctcctgtg ctccattttt aaaaaaggca attgaaacat
     4861 gaggttgaca ggcttctaca ctagcttcaa tagcgttgtc acaaaggata gacacaacgg
     4921 ttagaaaatc aagtagactc atcccctcta cctgaatctc ctctggaact tcgacattaa
     4981 agacaatgtt cttatctcta gcttttataa attttccagc taggagactt ttgagggcac
     5041 gatcccgaac attcaccaat cggccaaggt catatttatt gtcctgcaat ttctgactgg
     5101 aatcccttaa gaccgagtcg tagatctctt ttatctgctc catatcctcc tcttcaatgc
     5161 ccaaacgtaa gctggttaag aggttagtgt agtcatggcg aaaactccga atttccttgt
     5221 aaagttcctc tatatgccga ctatagcgtt ccatatctct gtagcgcaag gtctgctctt
     5281 ggttcagttc ctcctgaagt ttttccttca aataggtatc caatttcttg atacccccca
     5341 taaaaaagag taggtaaaac actaggatga gatggcgaac agtcgttgat tgaatacctt
     5401 gttcatattc aaggtaagat agactttgca tcactagata ataagccccc attgcccagt
     5461 taatcttagt aagagacttt tgaaaacctg tatctagaaa ctcccttctc aatctagtga
     5521 aatcatagtc taaccatttc aaaaagacta aaactatgaa gcaaacgaat atcataatca
     5581 ataaaaagat aggattgcca tccccatcta caattccttg ccccaaaaat ggaagcacaa
     5641 aataggaaac acctctgtaa aagagctcta ctaatatcat tgggaagaga ccataaaaaa
     5701 taaggatttt tttaggaagc cctcttaaca ataagaaaga tagacctata ccgaacaaag
     5761 gttctataaa ataggacaaa tatttactta cagccaaaaa ttgaaaagtc gtaaaaatga
     5821 tccctagaag aaatttcaga agaaaggcct taaaaatcct ctcgaaagta agatcaattc
     5881 catccacctt aaagaagatg acaatttcta gtccattagt aacaagtgta tacaacaata
     5941 tccaagcaat gttcataaat tctcctagct cagtgtaatt tattgatggc ctcagacact
     6001 tccctgacct tataacgggc gattagacaa cttccaccat tgggaaagaa aagcagtttt
     6061 tctttcttat ccaaatgcac cacatttgca ggattgatga gaaaagagcg gtggcactgc
     6121 aagagacggg gctcctgctt gaaaacctcc tctaaactcg ctgtaaattc cagcctgtct
     6181 gtcttggtat agagaataac acgatgggct ctgggcgacg tttcgagata gtaaacctct
     6241 ttaaaaggat actgaaattg ggcaaatttt gatttaaagt aaaagcaatc ttccgccaga
     6301 cttttactat cttgactatt ggcatagagg agggctgtct cgatccgaga ttcaaactcc
     6361 tctgctgaca aggccttatc aatgtagtcc aaagcagaca cttggtagcg aaaagacagg
     6421 ggcataaact ccgagtgagt cgtcacaaag acaatcaggg cataaggatc ccgatcccga
     6481 atctttctag ccacttccag tcccttcatc tcttcatttc gaatctcaat atccaaaaag
     6541 aatagctgat gggccccctt ctcatgcact tcagccagca gttggtccgg cttgccaaat
     6601 acctcaaaag agctaggaat gatatgatgt gctttcaaaa gtttctcaat cgtcgtttca
     6661 attctagtct gttgggaaaa atcatcctct aaaacaaata ttctcatctt cttactctcc
     6721 ctctttcaac catttttgac gaatttctct atagcgacgt ctggcatact tgacagcgta
     6781 ttgaccttct tctccgagaa aaaggattct ttcttgaaaa tcaatcgatt ttaatttatc
     6841 aagattaacc aaacaatttc gatgacatct catcaaggtt tccccacatt ggttctcaag
     6901 attacttaaa ttttgaagca tattaaaact agcttcttct gtaacaatct gtacggtatg
     6961 ggctttagtt ggatgtgttt ggatatagta gatatcgtcg atgtttactt tatagactgt
     7021 tttctgcgtc tgaataatca tatatttcat tggattctcc tcctaagaaa agaataacag
     7081 aaaaggtcta gcccaagcac acccaatcct aaacagtctt tgaaaactcc taaaaggatt
     7141 attttctaca acatcatgat gagcttacaa ctattttatc ataaaattca ctcagcgcaa
     7201 ttcaagacat ttcaatgaca attaaagatt tgaataaaaa aaaagaatta aaagtgataa
     7261 actaacagta tcaaaacaca gttgccagaa gtaagactgg cacccagatt aaaggaggca
     7321 ttcccatgac agatacagac cccatcaaaa gagctcatac tttgattact gacttaaaca
     7381 aagcctacca agcatgcaaa caggcaagcg ctgacgacgt ccgctttcag gagcaattaa
     7441 actctattct tggttttcta gccaaggctg aaacagtgga taatcgattc ttgattgaac
     7501 tagaaaaatt ttaccagact tccagtcttc tcatgggact cagcgctctt gatccagatg
     7561 ctccaactcg cgccgcttgg cgggcctatg accgcttcca ctttgaccaa gtcaagacca
     7621 agttaatact caatgaaaat caaagagcaa actaggaagc tagccgcaag ctgtacttga
     7681 gtacggtaag acgacgctga cgtggtttga agagattttc gaagagtata agtctctacg
     7741 gaccaaccat tatcctgtag taacaaaaaa gaagttgaga cagactgaac tcaacttctt
     7801 ttttagtgtc gtatcagcaa tgttagtcct gcatctgacg ttttacctga taaggcaaat
     7861 acaagactag taaaaccaaa ccagctccta gtaaggctag aagggctagt ttttcttgga
     7921 aggtaatcaa cccaacaact aattccacaa gtaaaacaaa actggtcaat cctcgaacta
     7981 cctcctgtaa gcctttttcc ttttgcccct tgtccagcgg aaagagttgg gtcaaatact
     8041 ggtagtcaaa ggcatgatag agggccagca actggaagag caagaggtag ttaaagagaa
     8101 ctaccactgc tgtcgcaatc caagcttgct cgataaaaac ctgcgccagt acggaaagta
     8161 agagaagacg aagactgaga gcaaagaggt cgccatttcg cagataagaa cgcagataga
     8221 gattttgcca aatcttccca ggcaccttct gaacagcctt taagataaag tccagatagg
     8281 cacgacgctt aacgctgttt gaaattccct tgacctgcgt aaagagggca aagaaacgaa
     8341 gcaagacttg cttacgcttg ctttcttggg aaatgacata gtcccagtcc agcccagttt
     8401 cagtgaaaaa tttgctggcc ttttgacgaa agtggaaata ttttcctacc cccaataaaa
     8461 gcacatagag cagaaaaact ggcaagccat aacccattgc taaaaataaa ggcgcaaata
     8521 acagcaagaa aagggtctgt acaaagagcc aaaagactag ggaaatgcca gtttgacgct
     8581 tgagatggag cttgatttcc tcttctccaa ctaagagaaa gagcttgtct ggagcctcca
     8641 tataggtggc aattcctccc caaagtaaaa gtaaaacaga cgtaattcct acaaacaaaa
     8701 ggataggcca atgattttca ggaaaatgtt gtaagagttg actgtactgg taggctagaa
     8761 agcccaacag gacaagcagg aacaagacaa agtggtcatt gagcacatag cgcagataac
     8821 caagacactc cttacgaaag gcctgctttc tctttaaaaa caagtctttc atagatcctc
     8881 ctctttggtc agagccaagt aaatatcatt caaactagcc tcaggcatat caaaggcttc
     8941 acgtagttgc aggagattgc ctttggcacg cacctctccc ttgtgaagaa tgacaaaggc
     9001 atcacacatc ttctccgccg aatccagcac gtgggtactc atgagaatag acttgccctt
     9061 ttgcttctcc acttccaaaa gctgaatcaa atcagaaata gccagcggat caagaccaag
     9121 gaaaggctca tccacgatga aaagacttgg atccaccaca aaagcacaga taatcatgac
     9181 cttctgcttc atcccttttg aaaaatgaac agggaaccag tctaatttct gttccaaacg
     9241 gaacattttt aacaagggct ctactcgttc gaaagccact ttttgctcaa taccgtaagc
     9301 catagcaacc gtttcgatat gctctctgag ggtcaattcc tcatacagac taggcgtctc
     9361 aggaatgtag ccaatctgct tgcggtagct agtcgcatct ccttgcagag tcaggccatt
     9421 gatattgatg gagccactat aaggtgccaa cagaccgata atctcattga tcgtcgttga
     9481 tttcccagca ccattgagac caatcaaacc gaccaactgc ccactttcaa cagtaaagga
     9541 cacatctttc aaaacaggaa catgaacata gccacctgtc aggtttttaa tttctaacat
     9601 attttctcca aatctggtat aatgtagcta tattatatca aaattcagta cagtagaggt
     9661 agattttatg tcagattgca ttttttgtaa aatcatcgca ggggaaattc ctgcttcaaa
     9721 agtatatgaa gatgagcagg tccttgcctt tcttgatatc tctcaagtaa cactaggaca
     9781 caccttggtc gtgccaaaag aacactatcg caatcttttg gagatggatg ctacgagcgc
     9841 cagccaactc tttgcccaag taccaaaagt agctcaaaaa gtcatgaaag tcactaaggc
     9901 tgctggtatg aatatcattt ccaactgtga agaagtcgct ggtcaaacag tttttcatac
     9961 tcacgttcac cttgtgcctc gctacagtgc tgacgatgac ctcaagattg attttatcgc
    10021 ccacgaacca gactttgaca aacttgctca agtcgctgaa accatcaaaa acgcttaagg
    10081 agttgctatg aaattatcca acctactgct atttgcagga gctgcagccg gaagttatct
    10141 ggttacaaaa aatcgccaaa ccatcacaga tgaagtcttg aataccactg accgcgttca
    10201 agctatcaag gacgatgtgg atattatcca aaacagcctg caaatcatta accagcaaaa
    10261 agaacttatc aaggaatacc aagaagactt gacttacaag tttaaggtct tggaaaagga
    10321 tatccagact agactagctg tgataaaaga aatgcaggga actgaagata agtaaaaaga
    10381 gcccgacggc tcttttttaa aacgtaaaca agttatagtg aattgaattt agaatagcac
    10441 atcatagttt ctaaagcatt gttagagatt actttaaaat cctcttatca atttgttcat
    10501 attctatttc aatctactat atatatccca tcaactatgc atcataattt aggtaactca
    10561 tactcaataa aaatcaaaaa gcaaactaga aagctaggca cagactgctc aaaacaccgt
    10621 tttaaggttg tggatagaac tgacgaagtc agctcaaaac actgttttga ggttgtggat
    10681 agaactgacg aagtcagtaa ccatacccat gacaagccga cgctgacgtg gtttgaagaa
    10741 atttttgaag agtatcattc accatttcac aactaaatcg aagactttct gccgtaatga
    10801 aaacacctga aacagcttgg tttcagctgt ccggaaactt taagacttag gttcaaagtt
    10861 taggtatgga acttcgaagg aggtcgctac cgtccgtcat tacttaggaa agtcttaaaa
    10921 aatctataaa gtaaaaagag cccgacagct ctttttgttt atactcaatg aaaatcaaaa
    10981 agcaaactag gaaactagcc acgggctgct caaaacactg ttttgaggtt gtagatacga
    11041 ctcacatata tacggcaagg caacgctgac gtggtttgaa gagattttcg aagagtatta
    11101 ttctccatca aaggcatctt ttatatggtc aaagaagcct tttttctttg gatttacttt
    11161 caagtcacca gcagtcgcga attctttcaa ggctactttt tggcggtcgt tcaagcctgt
    11221 cggtgttacg acattaacag taacgtattg gtcaccaact gcaccgccac gaaggctcgg
    11281 tgccccctta ctacgtaggc ggaatttctt accagtctga gttccctctg gaataaccaa
    11341 ttcaacatca ccgtgaacag ttggaatatc tactgtatca ccaagagccg cttggacaaa
    11401 gttgaggttg agattgtaga agatagtcgt tccttcacgt tcaaacttgt cgctagcttc
    11461 tacagaaact actacataca agtcaccata aggtccaccg ttaaagcctg cttcaccttg
    11521 accagcgagg cgaatttgtt gacctgtttc cacaccagca gggattttca catgtacgct
    11581 atgagcttgt ttctcatgac ctgttccatg acaggttgta catggatatt tgatttcttt
    11641 tcctcgaccg tgacagacat cacaggttac ttggcgacgc atcataccaa gaggagtctg
    11701 cgtatcgacg ttaatgacac cagcgccatg acagcgtcca caagtgactg gacttgtccc
    11761 tggcttagca ccagagccat tacatgtacg acagccagct tcacgatgat acttaacttc
    11821 cttctcagtt ccgaagatag cttcttcaaa ggtcaaattg acacgatact ggagatcatc
    11881 tccttggcga ggagcgtttg gattgcgcga agaaccgcct ccgccgaaga aacttgagaa
    11941 aatatcctca aaaccaccga agccacctgc cccattgaaa ccaccgaaac caccagctcc
    12001 accaaaacca ccattggcgc ctgcagcacc atactggtca taggcagcac gtttttggtc
    12061 gtcactcaaa gtctcatagg cttcttgaac ttccttgtac ttgtcctcag caccaggctc
    12121 cttgttgata tctgggtgat attttttgga aagcttacga taagcctttt tgatttcgtc
    12181 tgccgaagcg tttttggata cccccagacg atcataaaat tcagtattgt tcatacaaga
    12241 taccaagacc gtaaaattcg actgaaaaat aggaaatctg acgctggagc gacgctccta
    12301 gacagatttc tcttttttcc gagaatttag gtcgggttca attcctttct tttatattga
    12361 tgagataata ctccagccac tcggccctat ccctttttac cgaaaaacag aggctgggtt
    12421 gcaacctctg tggttagatt attcatttga aataaaaatg gttgtattat ctctagtagt
    12481 aatcttcaaa gaccttttag ctaaatcaaa ctcaaattta ttatagtgtg ggtcttgtgt
    12541 tttatatagg tgtaactcct gacatatatg atccgaaaag taaatcataa catctttaaa
    12601 cacagaagtg tggtcatatt tactcttacc aacagctact tctgtaaatt ctttataaat
    12661 gacatttcca tttctttcca cagtcaccag catttctgtt ggattataat ccaaattaaa
    12721 taattattca aaaaaacttt atcttttcat gataatctgc aatgtcagaa agattatttt
    12781 tattaacact cataacacta gccccttatt tttcagtaaa ctctccgtct acgacgtcat
    12841 cgcctgcgtt tcctgttgct tgtgcgcctt ctgctccttc ttgagcttgt tgcgctgctg
    12901 cggcttgttc gtagagtttc acagcaaggc cttgagcttt ttcgttcaac gcttcaagtt
    12961 tcgctttcat gtcgtccaag ttgttgtctt cttgagcttt cttaaggtca tcaagggcag
    13021 cttgggcagc gtcacgttct gcgtcgaagc ctttaccttc agtttccttg attgtctttt
    13081 cagtcgcaaa gattgcttgg tctacttcat tacgaaggtc tacttcttct ttacgtttct
    13141 tatcggcttc agcgtttgct tctgcatctt tcatcatgcg gtcgatttct tcgtcagtca
    13201 aacctgagtt cgattggatg acaatagttt gttctttttg agttccaagg tctttggcct
    13261 taacagacac gataccgttc ttgtcgatgt caaatgttac ttcgatttga ggaattccac
    13321 gaggtgcagc tgggatatca gtcaattgga agcgtccaag agtcttgtta tctgctgcca
    13381 ttgggcgttc accttgaaga acgtggatat caacggctgg ttggttgtct gctgctgttg
    13441 agaagacttg tgatttagat gttgggattg tagtgttgcg atcgataagt tttgtaaata
    13501 ctccacccat tgtttcgata ccaagtgaca atggcgttac atcaagaagg acaacgtcct
    13561 tgacatcacc agtaatcaca ccaccttgga tagccgcacc catagcaact acttcatcag
    13621 ggtttactga tttgtttggt tctttaccag tttcagcttt aacagcttca acaacggcag
    13681 ggatacgagt tgaaccacca acaaggataa cttcgtcgat ttctgacaag ctcaaacctg
    13741 catctgaaag ggcttgacga actggaactt ttgtacgttc aacaaggtca cgagtcaaat
    13801 catcaaattt cgcacgagtc aaagtcattt ccaagtgaag aggtccagcc tcacctgcag
    13861 tgataaatgg caagctgatt tgtgttgaag ttacaccaga aaggtctttc ttcgcttttt
    13921 cagccgcatc tttcaaacgt tgcattgcca tcttgtcagt agacaagtcg ataccgtttt
    13981 ctttcttgaa ttctgctacc aagtggtcaa tgattttttg gtcaaagtcg tcaccaccaa
    14041 gtttgttgtc ccctgcagtt gacaatacgt cgaagacacc gtcacccaat tcaaggatag
    14101 agacgtcgaa tgtaccacca ccaaggtcaa ataccaagat tttttcttct ttgtcagtct
    14161 tgtccaaacc ataagcaaga gctgctgcag ttggttcgtt aacaatacgt tctacttcaa
    14221 gaccagcaat tttaccagca tcttttgttg cttgacgttg agcgtcgttg aagtaagccg
    14281 gaactgtgat aacagctttg gttactttct caccaaggta gtcttcagcg tagcctttca
    14341 agtattgaag gatcatagct gagatttctt gtggagtgta ttcttttcca tttgcagaaa
    14401 ctttttcaga agttcccatc ttagatttga tagagataac tgtatctggg tttgtgactg
    14461 cttgacgttt tgcagcatca ccaacgatga tttctccgtt tttgaatgag actacagatg
    14521 gagttgtgcg gtttccttct gggtttgcga tgattttgct ttcagttcct tcaagaactg
    14581 caactgctga gtttgttgta cctaagtcaa taccgataat tttagacatg tgtttttctc
    14641 cttgttagtt aattttctat ttttcttttt gatactcttc ttaagtggcg acgccgtcag
    14701 agcttgactt cgtcaatctc tttgactaaa ctttgagcct aaggtctcaa aatttgcgca
    14761 aatagcacca cggcgaagag tatcgtcttt ggttcgcttc gctcactatt acaaagccaa
    14821 acatatttta tctttcttca tagtttattg tcgtttcgga caagttttct attatgtaaa
    14881 ttgcgacacg aggagtcgaa atcgatttta tttcgacgac gagttagtaa ggaagctagg
    14941 caaacgtcat agcgattgcc gttttctgac gagttgcttt agctaccgtc agaattgccg
    15001 aatcgaacac gccctaagct ctgagtaaaa aagatagatt ttcttgtgtt catcgaacac
    15061 ttcgtcaatc tcctattttt actgcgagct ttttacgagc tttgtatctt agttatacac
    15121 cactaccatt gctgggcgta ggatgcggtc atggagtttg tagccttttt gaaagacttg
    15181 ggcgatggta tctactgggt gttcatcgtc tgctgggaga gtttggatgg ccatatggta
    15241 gttatggtca aattcgccat ctgctgcgat ttcttcaatt ccttcttctt tcaaagcgtg
    15301 aatcaagctt tcttgcacca tcgccaagcc cttcttcaca tcatctgtca aaccttcaac
    15361 tgcaagtgca cgctcaaggt tgtcaagaga tggtaagatt gcttttgcca agtcctggct
    15421 acgataacgt tgcaagtttt gacgttcttc attggcacgg cgttggatat tttgcatttc
    15481 tgcatgagcg cgaagatatt tgttttcgaa ctcatctgca cgttcatttg ccaagtccaa
    15541 ctcagacttt tcaggagttg tttcttcagc tgtttccaca acttcctctt cttgaacttc
    15601 ttctacttct tcatttttta tatcttgggc catgttcgcc tcctttaatg atttcaatct
    15661 taatgtactt cgtaatgatt actgctgagg tagcggtaaa aatctgtcaa cttcatggtc
    15721 aaaacacggt tgaccacatt gacttgattg attagctgtt ggtaatccag attaactgga
    15781 ccgataatgg ctagaattcc aactcctcga taaggaatga ggaacttact actaatcacc
    15841 gctaggtcag ctaaacagga ctcttgaccg tctgcaacac gaacattttg catctgatcc
    15901 tcacgcaacc cctcacgaat ctccaaggcc accttttgcg gttggtcaaa gaactgatag
    15961 gcttctagat tggcaaaatt caagagattg accttgcccg ccatcacaat gttttcgttg
    16021 aacatttcct taaagatgtg ttcaaagaga tcgatgacat tatccgttgt tgtaaagtaa
    16081 cgctggataa tctgcggaat ctccgtccga atcttgtagt gaatatctaa aacggtgtga
    16141 ccgaggaaac gttcctgaat gatgctcttc agtttcagca aatcctcctg caagaagttc
    16201 cttggaatca gaaactgact agtaaccgtt cgcgactcgt ctagggtaaa taccgccaag
    16261 gctgtatgtt gccccaaaac aacgatatca aaggctgtca aacgttgcct gctcggctca
    16321 acatccagtg ccactaccgt acagccactc aggtctgtta gcaagttagc agcctcttgc
    16381 agaatatcct ccaatttgaa gaattcctga tcaaaggctt tgacaatctc atatacctca
    16441 ttttcagcca gccggtgaaa atccagtgag tgtttcacat agtactgaaa accagcaaca
    16501 cttggcatcc gaccgcttga agtatgagcc ttctcaagca acccttgttt ttctagttcc
    16561 gccatgtcat tacgaatggt tgcactgcta gagttaatag actcttgcaa ggcttttgat
    16621 ccgacaggtt cgtgcgtttt ggtaaagatg tcaataatca gatttaaaat atcctgctga
    16681 cgctctgtaa ccatctcatc actcctctct gtctgatcaa ttagcactca atgcatccaa
    16741 gtgctaactt atgattctat tatacaccct taaaagagaa tgtcaagaca aaaactcaaa
    16801 aaattagcac tcttttatca agagtgctaa aaatcaatct gaagacctag aaccttgcta
    16861 ttcatctact cgatatttcc tttttagtct gaaataacca tgaattagat aagaaatcag
    16921 aaaagcatat aaaacaaaaa taagaaagaa agacatagaa agatcctctc taaacaaact
    16981 cgtacaaaca acaagaccac ctaagaaagt agttgtacag gaacgaagtc tagatcgcat
    17041 aacttcccat ttgagcccct tactcatata gacttgatcc tctggaagta aatcagaaga
    17101 cgatttacga agaatcgaac aagaacctgc tcctatcaat tcccaacctc tatctctaaa
    17161 atcttgcagt tcatgcttat attttttaag aaatctagaa tcatagatac ggtagatgac
    17221 atcgtctggt tgacattggt caaaatagaa caaaccaaaa cgactcgttc tatacctcca
    17281 acctttcaaa tgcatctcat gtaaatattc ttcttacttg tccaaatcaa caatggtgaa
    17341 aatccgaaat tctactctgc tattcattgt cttaccccaa aattagaaaa catgcctggc
    17401 gttatttatt agataattct ttccactttt gactcaatct ccaaaaaata taagaaatct
    17461 gaatcgcaaa aactatcaat aaaacccaat ctattatgaa aatcaaaaac actttccaac
    17521 tgaaagaact acctccagtg acaaactttg agaaaaacgg tagtagagct aaaaagagaa
    17581 gtaaaatagg aagcatccgc attgttaaaa tccgtttggc ataaaaaaat ctttatttaa
    17641 actaaaatat tatatcaaaa tttacgccag tttttgaacg gctgatgtag atattttata
    17701 ctttcaaaat gtttaaatgt gattatttat ttttgaaaaa tagctcacca gcccgactga
    17761 aagtgcttat agaatgataa taagtcgcct gccgaaaaca gcggaaaata gcggtgttat
    17821 gcggagataa tctgacgcga tgcgaaagta tattgcatac ttattttcaa caatttagca
    17881 gagtattttt ataagtgtga tataatagaa gtataatttg ttctgatagt ttattttatg
    17941 gagaagtaga tttttagaat gcggagggtt caatatggtt gagtttataa agtctaagaa
    18001 agaaatgagt gaggaggata ttaaagcaaa tttcatcact cctgctattg tatccaaagg
    18061 atggaaaaat ggtgagcata tcgcttacga agaatacttc actgatggtc gaattgaggt
    18121 tagaggagat aaggctcgtc gtaaagaagg aaaaaaatca gactattcac tgtattacca
    18181 atttggaact cgaattgcaa ttgttgaggc aaaggataat aaacacagcg ttcgagcagg
    18241 attacaacaa gctattgaat atggagagat tttagatgtt ccatttgttt attcttcgaa
    18301 tggtgatggc tttattgaac acgaccgtat cacgagagaa gaacgtgagc tggagttaga
    18361 cgaattccct actcgtgaag aattattttc tcgtatgacg aaggaaaaag gattgacgta
    18421 cgaaattaca gaagctatct caactccata ctatacagac gccttctcaa tgaaaacgcc
    18481 acgctattat cagcaaatag ctatcaaccg tactattgaa acagttgcca gaggacaaaa
    18541 acgagtaatg tttgtgatgg caacaggaac ggggaaaacg ttcatggctt ttcaaattat
    18601 tcatcgcctt cgaaaagctg gtttggctaa acgagtttta ttcttagcgg atagaaacat
    18661 cttagtagac caaacgatgg ctgaagactt taggccattc gaaaaggtaa tgacgaaaat
    18721 tacaccaaaa cttttgactg ctcctgaaaa attaaattct tttgaaattt atctagggct
    18781 ttatcagcaa ctaactggtg aagatggaac tgaaacacat tatcaaaaat ttgacaaaga
    18841 cttctttgat ttaatcgtaa ttgatgaagc gcaccgtggt tcagctaagg aaaacagtaa
    18901 ctggcgtaag ataattgatt atttcagttc tgcgacacag attgggatga ccgctactcc
    18961 taaagaaacc aagaatgctt ccaatacgga atactttggt gagccaatct atacttatag
    19021 tttaaaacag ggaatcgagg atggtttttt ggctccatat cgtgttatga gagttaattt
    19081 agatgtagat gtggatggtt atcgtccaga aactggaaaa gttgatgcta acggacaatt
    19141 aatagaagat aggtactacg gcaggaaaga ttttgataaa accattgtca ttgatgatag
    19201 aacgcaaaga gttgccaagt ttgtttctga ttatatgaag caaaacaatg cacgatttga
    19261 taaaacaatt gttttttgtg ttgatattga ccatgccgag cgaatgcgtg ctgcacttgt
    19321 aaaagagaat ctagacttag tccaagaaga ctatcgttat gtcatgcaag taactggtga
    19381 caacgctgaa ggaaaagctc aactggataa ctttatggat gtcaattcta attttcccgc
    19441 tattgtaaca acgtctaaat tattaacgac aggagttaat gctaaaacat gtcgtttgat
    19501 tgttttagac tctaatatcc aatccatgac tgaatttaaa caaattattg gtcgtggcac
    19561 acgtctttat cctcaaaagg ggaaagaatt ttttacgatt attgattttc gaaatgttac
    19621 caatttgttt gctgaccctg attttgatgg tgatccagtg aaggtgctgg aaacaggtgc
    19681 gaaaacagtc agtggttcta cgcccggttt cgtaagtgag gaaggtgacc cagtagaaaa
    19741 atatatcgtt acagacaagc aggttaccat tcttaattct actgttcaag tattggatga
    19801 aaacgggaaa ctgattaccg aaagcctgac cgactacact cggaagaata tcttaggtag
    19861 ctacgccact ttgaacgatt ttatcacagt ttggcatacg gcggataaaa agaagcttat
    19921 cttagacgaa ctttataaaa aaggagttta tctagatgct attcgagagt cggagggaat
    19981 atcagaacaa gaaatcgatg attttgattt actcctaaaa cttgcctatg gtcaaaaaga
    20041 attaaccaaa acggaacgta tcaataagct caaacaaagc ggatatttat ataaatatag
    20101 tgaggaagcg cgtgctgttt tggaaatttt actgaacaaa tacatggata aaggtattgg
    20161 agaactcgaa agcattgaaa cattaaaact tccagaattt cagatatatg gtggaacctt
    20221 caaaatcatc aatacttatt ttggagataa aaaacgatat ttacaagcaa ttaaagaatt
    20281 ggagcaagag ctatttacag tagcttaatg aaaggaaagt atgtcaatta catcatttgt
    20341 aaaaagaatt caagatatca ctcgaaacga tgctggtgtt aatggtgatg ctcaacgtat
    20401 tgagcaaatg tcttggttat tattcttaaa aatttatgat agccgtgaaa tggtttggga
    20461 attagaagaa gacgagtatg agtcaattat cccagaggaa ttaaaatggc gaaattgggc
    20521 tcatgctcaa aatggggaac gggtattgac aggcgatgaa ttacttgatt ttgtcaataa
    20581 caagttattc aaagagttga aagagcttga aataacttca aatatgccta ttcgaaaaac
    20641 gattgttaaa tcagctttta aagatgcgaa caactatatg aaaaatggcg tcttgttacg
    20701 ccaagtcatc aatgttattg atgaagttga tttcaatagc cctgaagatc gtcattcgtt
    20761 taatgatatt tacgaaaaaa ttcttaaaga tattcaaaat gctgggaact caggagaatt
    20821 ttatacacca cgtgcagcga ctgattttat tgccgaagtt cttgacccaa aacttggaga
    20881 atcaatggca gaccttgctt gcggaacagg aggcttcttg acttcgactc tgaaccgttt
    20941 aagtagtcaa cgtaaaacta gtgaagatac caaaaaatat aatacagctg tttttggtat
    21001 tgaaaagaaa gcatttcctc atcttttagc agttacaaat ctgtttcttc acgaaattga
    21061 tgaccctaaa attgttcatg gaaatacttt agagaaaaat gttcgtgaat atacggatga
    21121 tgaaaaattt gacattatta tgatgaatcc accttttgga gggtcagaat tagaaacaat
    21181 aaaaaataac tttccagcag aattacggag ttctgaaaca gctgatttat ttatggctgt
    21241 cattatgtat cgtttgaaag aaaatggtcg tgttggagtt attttacctg atggttttct
    21301 atttggtgaa ggtgtaaaaa ctcgcttgaa acaaaaactg gtagatgagt tcaacttgca
    21361 tacgattatt aggttgcctc atagtgtctt tgcaccgtat acaggaatcc atacgaacat
    21421 tcttttcttt gataaaacaa agaaaacaga agaaacttgg ttttatcgtt tagatatgcc
    21481 agatggttat aaaaatttct cgaaaactaa gccgatgaag tcagaacact tcaatcctgt
    21541 tcgtgactgg tgggaaaatc gtgaagagat tctggaaggt aagttctaca aatctaaatc
    21601 atttacacct agtgaattgg ctgagttgaa ttataattta gaccagtgtg gttttccaaa
    21661 agaggaagag gaaatcttaa atccctttga gttgattcag aattatcaag cggaaagagc
    21721 aactttaaat cataagattg ataatgtatt agctgatatt ttgcagttgt tggaggacaa
    21781 ataatgacac cagaacaact taaggcaagt attctccaaa gagcgatgga agggaaatta
    21841 gtgccgcaaa atcccaatga cgaacctgca agtgaattat taaagagaat taaagctgaa
    21901 aaagaaaaac ttatcagtga aggaaaaatc aaacgagata aaaaggaaac tgagatattt
    21961 cgtggtgatg atgggaaaca ttatgggaag tttgctgatg gaagtactca agaaattgat
    22021 gttccttatg atattcctga tacttgggag tgggtgaggt tttctacatt ggttgaaatt
    22081 gtcagaggtg gctctccacg accaatcaaa gattatctta cttctgaagt agatggaata
    22141 aattggataa aaataggtga tactgaaaag ggtgaaaagt atataaataa tgttaaagaa
    22201 aaaatcaaaa aatcagggct taacaaaact agatttgtaa aaaaaggtac atttttgtta
    22261 actaattcta tgagttttgg tagaccttat attttgaatg ttgatggtgc aatacacgat
    22321 ggatggttgg ctatttcgaa ctatgaaaac tcattaaata aagattacct attctatatt
    22381 ctttcatcaa atgtagttta ttctcaattt ctatctctaa ttagtggagc tgttgtgaaa
    22441 aacttgaata gtgataaagt tgcttctatt cttatccctc tccccccact atccgaacaa
    22501 caacgcataa tagaagcaat cgaatcagct ttagaaaaag tagatgaata tgctgaaagt
    22561 tataatagac tagaacagct agataaagaa tttccagata aactaaaaaa atctattctt
    22621 caatatgcta tgcaaggaaa attagttgaa caagacccaa atgatgaatc agtcgaagtt
    22681 ttacttgaaa aaatacgagc agaaaaacaa aaactctttg aagaaggcaa gattaaaaag
    22741 aaagatttgg acatttctat tgtttcccaa ggagatgata actcttatta tgaggaagta
    22801 ccttgtgaaa taccagaaag ttgggaatgg gtgaggttaa acgatataac ctcctacatt
    22861 caaagaggga agtctccaaa atattcaaat attcctatat accctgtgat tgctcagaaa
    22921 tgtaatcaat ggtctggctt ttctattgac ttagcaagat ttattgatcc caaaacagtt
    22981 catagttacc agaaagaaag attactaaga gatggtgatt taatgtggaa ttcaacaggt
    23041 ctaggtacgt taggacgatt agctatttac catgaaaata aaaatcctta tggctgggct
    23101 gttgcagata gccatgttac agttataaga gtcttatcgg gggttattaa ttgccatttc
    23161 atctataatt ttctttcctc tcctattgtt cagtcagtta ttgaagaaaa agcgtcgggt
    23221 agtacaaaac aaaaagaatt attaacgaaa actataaaag aatatttaat ccccctccca
    23281 ccccttcctg aacaatccag aatcgttgat aaaatcgaac aatttttcgc ccatattgac
    23341 gcactaattt agtataatag ttttacgtgc ggtggaattt ctatcaaaca taagatagga
    23401 gttttacgtt gaaagatttt gaattacatt tgaagaaagc tggtttagct gaaaatactg
    23461 tgcgttcgta cctttatggt gttcgatttt tcttggagaa ttacgaactc aaaatggaag
    23521 atttatttga atacaaagga tatttattag acaattttaa acctaaaact gtcaatttgc
    23581 gactacaagg agtaaataaa tatctggctt ttattggtca tgatgatttg aaattaaaat
    23641 ttgtcaaagt acagcaaaaa ccgtttttag aagatgtcat tagccatgct gattaccttt
    23701 ttcttaaacg tagtttgaaa aaagatggta ttttaaaatg gcattttgtc gtttggtttt
    23761 taggtgcaac tggggctcgt gtaagtgaac ttattaaact aaaagtagag catgtagaaa
    23821 tcggttattt tgacatttac tcaaaaggtg gtaaaattcg tagactgtac attcctaaaa
    23881 aattaagaaa tagttgtctt agttggttag aatcagaaaa tcgccgaagt ggttatttat
    23941 ttttgaataa atttaacgaa ccaattacag caagaggagt tgctcaacag ttaaaaaatt
    24001 atgctgataa atacaaaatg aatcctaaag taatttaccc tcattctttt aggcatttat
    24061 ttgctaagaa ttttttagcg aagtataatg atattgcctt gcttgcagat ttgatgggac
    24121 acgaaagtat agaaactact cgaatttatc taaggaaaac agctactgaa caacaaaata
    24181 ttgtagataa aattgttaat tggtaaaaaa taacaggtgg tcaaactgac tacctgctat
    24241 ttttgtgatt atggctctta ttatgggaat atacctatga attgggttgt tataaaaata
    24301 aaagatattt tttcaatgaa tacaggtctt tcttacaaga agggcgattt aagcattaat
    24361 aataaaggtg ttagaattat acgtggtggt aatattaagc ctttagaatt ttctctgttg
    24421 gataacgatt actacattga tacacaattc atctcctctg agcaagttta tttaaaacat
    24481 aatcagctaa taacacctgt atcaacctct ttagaacata ttggaaagtt tgcaagaatc
    24541 gataaagact atgatggtgt tgtggctggt ggatttattt tccaattaac accattcgaa
    24601 agttcagaga ttatttcaaa atttctatta tttaacttgt cctctccgtt attttataaa
    24661 caattgaaag cattaactaa actatcaggt caagctttat ataatattcc taaaactaca
    24721 ctgagcgagc tattaattcc gttagctcct tttgaggaac aggaacttat tactcaaaaa
    24781 gttgagaaac tttttgaaaa agtaaatcaa ctttgaaaat gattcttttc atctcttcat
    24841 gattagaaat agggattaat aattcggaga tactggtact atttaatgtt ttccctttga
    24901 tagcatcttt tgaatcacct aaagtagaga taagtggcaa aaatatcatt aagtaatctc
    24961 tgataatatt ttctttatta gcatagggga atatcgatat aatggcttca ttatgagtgg
    25021 caggaatatc caatatggca acttttccaa tagataattt aaaactcatt aataaagttc
    25081 ctttaggtga aatgtctatt ttctttgatt ttaatgctaa tttagaaata gattctctcg
    25141 tattagttac ataaccagat ataggcatat ctgatataga tacccaaggt atttcagttc
    25201 cccaaaaagt agcttcactg cgtggaggag tttttcctat tctgaagtta actaggctag
    25261 caaatttaat atatctccat gcttctggga tttcatatat aggataagag gttgtttcgt
    25321 ctttgttc
//
LOCUS       DAVKMJ010000031        24686 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000031 DAVKMJ010000000
VERSION     DAVKMJ010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24686
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.031"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(318..536)
                     /locus_tag="VW348_001419"
     CDS             complement(318..536)
                     /locus_tag="VW348_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9746306.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(782..1060)
                     /locus_tag="VW348_001420"
     CDS             complement(782..1060)
                     /locus_tag="VW348_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746307.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWYAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(1274..2905)
                     /gene="rlmD"
                     /locus_tag="VW348_001421"
     CDS             complement(1274..2905)
                     /gene="rlmD"
                     /locus_tag="VW348_001421"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU9746308.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKIFMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2979..3953)
                     /locus_tag="VW348_001422"
     CDS             complement(2979..3953)
                     /locus_tag="VW348_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEU9746309.1"
                     /translation="MRKKLFLTSAAILWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(4027..4641)
                     /gene="pmp23"
                     /locus_tag="VW348_001423"
     CDS             complement(4027..4641)
                     /gene="pmp23"
                     /locus_tag="VW348_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEU9746310.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(4641..5615)
                     /locus_tag="VW348_001424"
     CDS             complement(4641..5615)
                     /locus_tag="VW348_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEU9746311.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(5623..6879)
                     /locus_tag="VW348_001425"
     CDS             complement(5623..6879)
                     /locus_tag="VW348_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEU9746312.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYESLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6941..7372)
                     /locus_tag="VW348_001426"
     CDS             complement(6941..7372)
                     /locus_tag="VW348_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9746313.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSLEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGEGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(7374..7976)
                     /locus_tag="VW348_001427"
     CDS             complement(7374..7976)
                     /locus_tag="VW348_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEU9746314.1"
                     /translation="MIDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7960..8799)
                     /gene="prmC"
                     /locus_tag="VW348_001428"
     CDS             complement(7960..8799)
                     /gene="prmC"
                     /locus_tag="VW348_001428"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEU9746315.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASNQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQNRMVVVDD
                     RQD"
     gene            complement(8799..9878)
                     /gene="prfA"
                     /locus_tag="VW348_001429"
     CDS             complement(8799..9878)
                     /gene="prfA"
                     /locus_tag="VW348_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEU9746316.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLKELNK"
     gene            complement(9888..10367)
                     /locus_tag="VW348_001430"
     CDS             complement(9888..10367)
                     /locus_tag="VW348_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9746317.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDVIIGFVMIAYDKKIVISSGNYLLFCFMIDKNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEISENEVVAIYDLTIEK"
     gene            complement(10357..10956)
                     /locus_tag="VW348_001431"
     CDS             complement(10357..10956)
                     /locus_tag="VW348_001431"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEU9746318.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPIMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            11080..11262
                     /locus_tag="VW348_001432"
     CDS             11080..11262
                     /locus_tag="VW348_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEU9746319.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            11399..12772
                     /gene="mnmE"
                     /locus_tag="VW348_001433"
     CDS             11399..12772
                     /gene="mnmE"
                     /locus_tag="VW348_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEU9746320.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEANLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLIEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(12819..13754)
                     /gene="dapA"
                     /locus_tag="VW348_001434"
     CDS             complement(12819..13754)
                     /gene="dapA"
                     /locus_tag="VW348_001434"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEU9746321.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13810..14886)
                     /locus_tag="VW348_001435"
     CDS             complement(13810..14886)
                     /locus_tag="VW348_001435"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEU9746322.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(15228..15300)
                     /locus_tag="VW348_001436"
     tRNA            complement(15228..15300)
                     /locus_tag="VW348_001436"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(15265..15267),aa:Thr,seq:ggt)
     gene            complement(15400..15909)
                     /locus_tag="VW348_001437"
     CDS             complement(15400..15909)
                     /locus_tag="VW348_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEU9746323.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIQKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15907..16003)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            16032..16463
                     /locus_tag="VW348_001438"
     CDS             16032..16463
                     /locus_tag="VW348_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEU9746324.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            16545..16922
                     /gene="mscL"
                     /locus_tag="VW348_001439"
     CDS             16545..16922
                     /gene="mscL"
                     /locus_tag="VW348_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEU9746325.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16964..18058)
                     /gene="hemH"
                     /locus_tag="VW348_001440"
     CDS             complement(16964..18058)
                     /gene="hemH"
                     /locus_tag="VW348_001440"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEU9746326.1"
                     /translation="MKKAILMMTFGSPEEISFEGVAEFFTNIRRGVRPQDHEIQTLYD
                     NYIRIGGTPLQRITREEVNLVKERLGEEYGIYFANKFSRPFIPDVIKQMETDGVEECI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEVLLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            complement(18136..19011)
                     /gene="srtG2"
                     /locus_tag="VW348_001441"
     CDS             complement(18136..19011)
                     /gene="srtG2"
                     /locus_tag="VW348_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG2"
                     /protein_id="HEU9746327.1"
                     /translation="MTVQKRARFKNVFLVFFCVFVALFSWQRVVEASDYDHYNPIEKD
                     ASSTGFETLQHLNKDVCGWISLDGTKVDYPLLQSQDNVKYLDRNAFGDYTIMGSIFLD
                     YRFNPNFTDFNTIIYGHSMASGAMFGEIKKFADKEFFDQHRYGSIYYNGRERGLEIFG
                     ILEVDAYDTEIYRTLSSKDEEHQAYYQYLLSKAKYKRDVSLTSTDKIVLLSTCFLNIT
                     NGRHILLAKITDAPVKVAQDESGEAVGTRYFDHGIPSHWIYILAFLLLIIVLLLLVLI
                     ILIIRRDKKTKEQKK"
     gene            complement(19089..20087)
                     /gene="srtG1"
                     /locus_tag="VW348_001442"
     CDS             complement(19089..20087)
                     /gene="srtG1"
                     /locus_tag="VW348_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000851047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG1"
                     /protein_id="HEU9746328.1"
                     /translation="MKTKREKPKKSLSRRLVLAVDGVINHLLLIFAALIFLFGFYALW
                     DSNQVYSLASSSEYEAYRPVTTQQDELASFSGFSKLQELNPEVLGWINVYGTNIDYPL
                     VQAKDNEKYLNKDSKGEFAATGAIFLDARNNPKFEDFNTIIYGHHVENGVMFGDVAKF
                     ADQEFFDQHRYGSIYYNGVEKGLEIFEMLEVDAYDFNIYDPGIQGEDRQQAYLDHLLS
                     VAMHKRDISLSPSDRIILLSTCFLDVTNGRHIVVAKITDTVPKNTFHTKKSKPFPYSV
                     FDDSSLGRFLSSIPLWIWYLILFVLFLLLIFLLLVLYLILRRRRESKKNARSRPFY"
     gene            complement(20105..21301)
                     /gene="pitB"
                     /locus_tag="VW348_001443"
     CDS             complement(20105..21301)
                     /gene="pitB"
                     /locus_tag="VW348_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus major pilin PitB"
                     /protein_id="HEU9746329.1"
                     /translation="MKKTFFKKLFTASIAAITALSVFRGVPTFADDNSAITKANGENN
                     AVVKINKTLNIAEGITTPTATFTFKFTEKTGQSSNGAPYQTGVAIPDRNVEYNKNDHP
                     TADKIQKATEDIFSGVAYGHAGEYVYDVAEAKTGWQAITKNGKTIDAMRYDKRTYEMH
                     VIVKNKVNGGVYISSVYFKENNKSNAPKVEPSEQGVYNLFDNTYTKDASKEPNPDDPS
                     QVDPNAKALTITKKVDGASGDKTRDFQFHIKIQLPSTNKTAETPVTNIIVKHGSKSEV
                     LAVVTPADTVEYNFTLKDGETFTVEQLPAGSKYTVTETGVAGYTDSSIYTTNGAEQTS
                     QGQKNVDFTLTDILIGEKKNDNKVTNKIDDVTPTGLLIDNLPFILMIGLGLAGFVVLS
                     KKRREA"
     gene            complement(21346..21897)
                     /gene="sipA"
                     /locus_tag="VW348_001444"
     CDS             complement(21346..21897)
                     /gene="sipA"
                     /locus_tag="VW348_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system signal peptidase SipA"
                     /protein_id="HEU9746330.1"
                     /translation="MLLKKKHKKPVTQVNRDKSPPSVWGDILYLVSKLLMVGFVLAIL
                     YFFVFGLLRYNDDGMKPALKDGDLVVYYRLDKRYSIGDLLVYSYKGKERVARVIATEG
                     STIDINENGLIINGSPQQEQDIYKETLLYKEGATFPMKVPAGQLFVLGDNRTTAVDSR
                     AFGTIPIQDTQGKVVTVIRRRGF"
     gene            complement(21897..23849)
                     /locus_tag="VW348_001445"
     CDS             complement(21897..23849)
                     /locus_tag="VW348_001445"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HEU9746331.1"
                     /translation="MDAGIGTGTNINAGLTEAQRLLQSARAGAKKVVILLSDGEANMY
                     YESNSGRTIYNYYSNPNVGRMIDTPYWFTSGLERGMLNISSLIAPKIDGFYSIKFRYI
                     GSNDSITSLKGYISGYNSGIPNEIFSANNENDLQQKFKEITDKILPLGVHHVTISDVL
                     SKYVQLLPGDASHLRVVKIKDGNEQELNDNQVTIETKKNEQGLVEVTAKFNPSYTLED
                     DAKYVLKFTVTSSQEAFDAIAGDKTLTSDDAEEADATKLYSNKGAKVAYSYGIGTSRT
                     KIKDYSEKPTFKPSDPLTVPVEIEWKGVDGKSNPSANRPPSVELNLNQKKDGSIKDSY
                     RKVTSPVQTNSFTENTSFAKVAKGYDYELKAPDAPGYTVEVQKTGTKEKPSFKVIYRQ
                     LPSLTVKKILEGEQSPNKSFTINVTLSDKDGKPINGKFGNTTVTNGKAQISLKNSQET
                     ALSYLPRDTHYKVEEVENSRTGYHVTYEKQEGTLSEDVQTIVTNHRLPTLSVIKKVTG
                     AFANLLQSFKITINVKDAQNKPLNGSYSAIVNNQKTTLQFTNGKATVDLKKDKTIKIL
                     DLPLNARYSIEEEASSSRGYQVSYDKKEGTLDANKSATVTNNKNSVPETGIDFLSSTL
                     VLGVVLPLGGIFFIILLGHLVVNRRK"
     gene            complement(23979..24482)
                     /locus_tag="VW348_001446"
     CDS             complement(23979..24482)
                     /locus_tag="VW348_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HEU9746332.1"
                     /translation="MNVQYDFKKIQYFTSILVIFLAILFLCAPINSLRADSITEPQTT
                     LHKTITPISGQKDQYELSLDITSKLGTETQSEPLDVVLVADLSGSMEERDVWSYSSRR
                     YISRIEALKHTLKGVNGRQGLIDTILSNSQNRLSIVGFAGKIDNQYNDRYYNEYYLSY
                     QYGTWPN"
BASE COUNT         7116 a         5132 c         4544 g         7894 t
ORIGIN      
        1 taataatata attttttcaa aaaaggatct agtttttatt tttagttaaa ttatgtctat
       61 atttttcatt aactcatcaa taaaaatttg tttgctaata tctctttctt ctgattttgt
      121 ttcaaggatt attgctacat cattcatatt tttaggtaaa taccaaccat ctggcttatc
      181 tgaatatccc ttgaagccta attgattaaa agtagttatt tgaccagtac cttgattgat
      241 gttttcttca acttcattaa agcctatact tctcttgcat aatccctaac ttgatcttct
      301 gtccttaaag tcattttcta ttcctcgtca ctaaaattat cttcaaaact aataatatca
      361 ttaggagtgc aagataaagc cttacatatt ctttctaaat tcttaaatgt aattggttta
      421 tcctttccca tttgtgccat aacatttgtt gtaagtcctg ccatagctat tacatctgtt
      481 ttctttagtc ctttttttgc taactgtatc cataatggtt tatagttaag tgccataata
      541 tccctctttt tttcttcatt agatttattt aattatagca taaatattga tttcattcaa
      601 tcttacattg atttagtgat ttgttttaga gaatttgttg tgttattccg tccttatttt
      661 gccataaatt gttttaagtg ggacctctta tccttaccat ttttacctcc taattttgag
      721 tataaaaaag acgatagagt ttttaatttc tatcgtctga gatttacata ttaaattttc
      781 atcacaaaat aagactcttt aaagaatctt taaattcatt ggtatgctgc ttacaatatc
      841 cattattaaa atggatattg taagcagcat accaactatt tattttttga gttttaaact
      901 ttggtagaag tcttgaactc cttatattta cataactatt tgcctctata actgttatga
      961 cacgaaacca acaagcaagt tcaagcacct ccatatcttt attcaaatga ggactaagat
     1021 attcacaaac tttatcataa acctctttat cttttttcat aaaaggggca tacaacttag
     1081 caaatttatc ctaaaatttt ttgttgcctt tatcaatcat ttcaacgctc ctttaaatat
     1141 aaaaatgatc ctatcaatct ttatattgag cctattttct aattgatacc ttgcaagaaa
     1201 ggaataatag ctgttcctat accaagtagg aatgtaataa atgcagaaag tcatatactg
     1261 tcattctttt ctattaaatc attttgaagt gtctcaaagc atccatgatg gcttcttctt
     1321 tttcaggtgt acactgtgga ataatttgtt tatccttttt agacttgttg taatgttctc
     1381 gtaattctat tccacatttc ttttttatct gtgcaatata taatgtcgaa acttttaatt
     1441 caaatttatt ccaaacatat tctttgattt gagcatatgt tgctttgctc tccgcacttg
     1501 tcaaatccat ctcatccagc tcaatttcaa cacttatgtg cttatcgaca tcaagtttgg
     1561 acaaaagtgc taccgtctcg acgtgatgcg tttgaggaaa tagatccacc ggctggactt
     1621 tcttcaattc atatcccaat tcttggtaga gtttgatatc acgcgccatg gttgcgacat
     1681 tgcaggagat ataggcgatg cgatcggctc ctgtttgggc gcttgctttg ataaagcttt
     1741 ctgtcaagcc cttgcgtgga ggatcaacca agataacggt tggttgaatc ccatctttaa
     1801 gccaattctt catagcattt tcagctgtgt cacagacata gtgggcgttt gaaatattgt
     1861 tcagctgagc atttttttta ctattctcaa ccgcttctgg aatcagttca acaccgtaga
     1921 cttctttgac atgcttggcg actgataaac caatggttcc aataccagaa taagcatcaa
     1981 taaccacgtc atcttttttt aactctgcaa agtcaatggc tgtttgatag agtttctccg
     2041 ccatttcagt attgacttgg taaaaggctg ggccagcgat ttggaagtca tttcccaaca
     2101 tctggtccgt aatatagtct tgaccataaa gagtgcgcca ctccttacca aaaatcgcat
     2161 tggtattctg gtcgttgata ttttgcatga cagacacaat ctctgggaac tgcttgataa
     2221 cttgttcaat caattggtca acacgaaaaa cttttggacg agttgtcacc aaaacgacca
     2281 tgatttgtcc tgaatagtga ccacgacgca ccacaagatt ccgaatcaat ccagactgtt
     2341 ccttttcgtc ataaggtttt aaatcaaaac gacggagcag gtctcgaaga gctactacga
     2401 cttggtcaat gacaggatcc tggataaaga aatcttcaag gggcatgagg ttatgcgaat
     2461 tcttacggaa aaatcctgtt tccaagacac cattcactcg acgaacgggc acctgcgcct
     2521 tattgcgata cttgactgga tgttccatac caagcgtttc agcaacttct acatctgcaa
     2581 ttccagcaat cttgtagaga ctgtccttga cttgcttggt tttaaacttg agctgttctg
     2641 gataagaaag gtgtcctaaa tccgcgattc ctgaacgcag gtaagccaaa tctagatctt
     2701 gattacggtg tggtgactgg acaaggtatt tttcaacttt tccaaagcca atctttttat
     2761 tgaccttgag gacacgcatg aaaatttttt cactcggtaa agcattctct acaaaaaaga
     2821 ccaaaccatc taccttggca actcctgccc cttcatgggt caaatcaaca atttcaactt
     2881 ctacaatatc atttttcttt aacattcttt tctctttcta ttggccgaca aaaaagacgg
     2941 caacgttacg gttaccatcc attataccat gaaatttctt aagaaccaaa actcttgaag
     3001 aagttgacaa gggcttgcca gagggagctt aagaagttac caccgtcctc tagcgcctta
     3061 tccgcatcaa agttaaggtt gatattttta aaactgtcgc cagcttgtga tacgatgctt
     3121 tgtttaaggt catttagggt tttagtgaaa tctgcattgc tgaggatatc actctttgag
     3181 agattcaagg caaaattgat gatgatattg atctggtttc ctgttatgac ctgatcaagt
     3241 ttgtaatttt ttaaggtatc ttcaacaatc ttgcggatat cttcttctgt cagatttccc
     3301 ttgctttctt tagctttggc gagtcctgac ttgatatcag ctagggcaac gtttaattta
     3361 ttagcatcat agcctgattt gtccttgttt tcagcattga tatctgacaa agcctttagc
     3421 tcttcttgag ccaaatcttt attggcttgc ggcaccttgg ctccattagc ttctagcgaa
     3481 tagtagatcc cagccaaagc actctcacct gtaactggaa tgggtgctgc tacagtgatt
     3541 ttggcgtgtt ccacacccaa agttacggct gcatttcggt acatatcctg agttacctta
     3601 gtgatgtttt caggtgtttc aatcttgacc tcaagtggcg atttgtcacc tagcttttga
     3661 atcttggctg atgaatacaa ctgtaagcta gagtcattgg ccacattcat gattttagaa
     3721 taaacatcag gtgtcatggt cttgagttct ttggtatctg ttgaggcatt gtagcccagt
     3781 tttttaagag tttgattttt ttggtcttca gatagggaag aacctaggac atattcaggt
     3841 tggacatagg tttcatcgat aactttttga acatctgttg ctgcatggac gctattcata
     3901 gctgttactg cccacaagat cgcagcgcta gtcagaaaga gtttctttct catagggaat
     3961 ttcctccttt acttctttag agtaatatat ctatcttaaa gaaaacttat aacaaaaaca
     4021 cctggtctag ccagatgttg aaaagagagt gaaacatttg atgatgtaaa ggttaagtcg
     4081 tacctgtcta gaataataat agtttcctcc atttacatag agttcagcac cgtgaaaaat
     4141 ggaaatgggg tgaatataac tataagtctt tccagtcgta ttaccaagca agggggcaac
     4201 agtctcacga gagtactgtt tggctagagc caaggtattt tccttgccat tttgggcgat
     4261 aaaatcgata taggcaggtc caaaattata ggcttgaaca gctgtccaga tatctacacc
     4321 cttcttctgc gccagataga gattgcctgt cagagtttga atgccttgcc gaatgctaga
     4381 ggcattatca ttgatggtgt tggtggaacc acttgcagac tcactagact gcataacatc
     4441 gccttctttt ccttttgttt cagtataaat catagcaagc acaagctctt cgtttgctgg
     4501 ggtgtctttt tcactcaata tttctcgcac catgggttga taggtcatga cttgtttgac
     4561 atcttgatga acgcggtaag ctttatagcc agcaaaaagg aagactgcta gtacaagcac
     4621 tcttcgaatt cgtttaaaca ttatttactt tggatatcct cgatattttt gattaagata
     4681 gagtaggttc cattttcgtt ttggataaac tcaacagact cggcgtcttg atagacgtta
     4741 ttgggaacga tgagctcaat tccatttgat aaggagagtt tttggttttc aaatttcttt
     4801 aattggcgac tggcatcaat ttcatcaaat tgaacaggtt ctggtacggc ttctttgact
     4861 tggtcaataa agctcaaacg agccgtcaga ttgttgtcaa aaaggtcatt agccaatttc
     4921 tcaggtgaca attcattgct ttcttctagg ttgttgaaaa tagctgattt gaccttggat
     4981 tgaaattgaa aatcatctgt gttaaaagat tcagcaattc tctgggctgt tttttccagt
     5041 tccttgatag attttttagg agaaatctta ggagcgacag caagaagatt atctgaaaaa
     5101 tagttcaaaa aagtcccgtt gtacttgatt cgtttttcaa tcaggtgata cttgcgactc
     5161 tgaagattga ccaccaaggc ctcgtcagca cccgttccaa atccaggcag gttattctga
     5221 gtcagcttga ttggattatc aacttctcct ccgaggtggg tcaaggtctc ccgcagggca
     5281 attcgcaaga aagcgaaatg ttctacacct tctttagaaa attgaacaaa aatcaagtca
     5341 ttggtcttga gattttcaga aatgctaaac tcctctttcc agagattagc cagcgttact
     5401 gatgtctcca acaaatcgtc tgtaatatga ttgaagaagg gattttcttc ttcgaaaatc
     5461 ccagtcttgg cttcatctga atacacatgt tcaatttttt tacgtaggta ttcttcgatt
     5521 tttggagtaa tattgagaaa cttatctgct aagaacagct cggtatcatc cggactgaac
     5581 tggtgaataa tggctttctt aatataaatg tccataaaag ttttattcct cgtataatgg
     5641 gaaggcatct gtcaattctt tgactgcact tctcacttct tctaatacag cctcattttc
     5701 tgaattctta agggttttaa tgatgagttc agccactttg cgactttctt cttcaccaaa
     5761 tccacgtgca gtaatggctg ctgctccgat acgaatccca cttgtcttga atggtgacaa
     5821 gctttcgtaa gggattgagt ttttatttaa ggtaatattg acttcatcca acaagttttg
     5881 agcaactttg ccgttttcta caactttagt cacatcaaca aggaagagat ggttttcagt
     5941 tccacctgaa ataatacgga aatcagggtc ttgcaagaag acatctgcca tagccttgct
     6001 gttcttaatt acattggcag catattcctt gaaggctgga tccaaaactt ctttgaagga
     6061 aactgcctta gccgccacaa catgctctaa aggaccgccc tgaatacctg ggaaaatagc
     6121 tgaattgatt tttttagcaa gttcttcgtc attggtcaaa atcaaaccac cacgaggacc
     6181 acgaagggtt ttgtgggtcg ttgttgttgt gatatgagcg tatggaactg ggcttggatg
     6241 aaggccagcc gcaaccaaac cagcgatatg ggccatgtcc accatgagct tcgcaccgac
     6301 agcatctgcg atttcacgga attttgaaaa atcgataatt tgagaatatg ctgaagcacc
     6361 agctacaatc agttttggtt ttacttcttg ggcttgtttc aagatagcat caaagtctaa
     6421 gagttccgtt tcaggatcaa cactataaga aacaaagttg taggtttgac cagagaagct
     6481 aacaggagcc ccatgagtca aatgaccacc tgatgccaaa tccattccca taaccgtatc
     6541 acctggctca atcaaggaca tgtaagccgc acagttagct tggcttcctg aatgtggttg
     6601 gacattggca aatttagcac cgaaaatttc ttttgcgcgt tcaatagcaa gagtctctac
     6661 aacgtctact acatcagttc caccataata acggcgtcct gggtaaccct cggcatattt
     6721 atttgtcaag atagaccctt gagctgccat aacagccttg gaaactacgt tttccgaagc
     6781 aattaactcg atattatttt gttggcgttc ttcttctttg gcaatagcat tccagagatc
     6841 agcatcatat gctttaaaat catctttgtc aaaaatcata ggtcttctcc tttattgtgt
     6901 gactagtcca ttagtttgat tttacaataa gaaaatcaaa ctaaaagatg cgaataaacc
     6961 gtttctgcat tttatcacaa gtatagccaa ctttttcata aaatgcatga gcacccagac
     7021 gatgattggc agaatttaag cggataaacc cataaccaca tcttttggct tcttgttcca
     7081 acccttgtag taaactttta ccgatacctt caccttgcgc ttgaggtgaa actgctaaag
     7141 ctaagatatt aaatcctgct ttggaataga gtgattcgta aacttcagcg tggacatatc
     7201 caagtaagac atgattagct gcatcctcat agccaagtag gaaatgatgg gaatcctgag
     7261 acagtctagc tagttggcta gccgtttcct ctagactaaa agtataaccc aaagcctctt
     7321 ggttgatgtc acatatcgct ttcacatctg tttcttgcaa atctcttagc atttcaagcc
     7381 tcctcaaaag aaatctctgg caaccgagca agaatatctt ctcgtttaat tgcgccttgg
     7441 cgtaagattt tcaccttgtc tccagacaaa tccacaatag ttgaatcctg tccagttaga
     7501 aaagcatcgt cttccagacc cagaacctct tggtcaaaat ccttcagaat ttgttcaaag
     7561 gttacaccac ttgcctgacc tgagatattg gcagacggcc caatcaaggg acctgtctct
     7621 cgaattaaat ccagtgtgat agggtgactg ggcatccgaa atccaatagt tgcaaggtca
     7681 gaatttaccc aatagggaac tcggtcattg gcttcgagaa taatggtcaa gggacctggc
     7741 aaaaaggtct ctacaagttt ttgtagataa gttggctgat tcttagaaaa gtgcaagata
     7801 tcctcgaaag aggcgatatt gagattgagt gccttatctc taggacgacg tttgagttgg
     7861 taaacatggt caactgcttt ttcatctaag gccttggcaa aaagaccata aacagtctct
     7921 gtaggtagaa cgacagctcc accattttcc aactcttgtc taatcctgtc tatcatcaac
     7981 cacgaccatc ctattttgac caaattggtc cttgagtgtt cgaactcttt tttcaggaag
     8041 atgtttccta aaaagttcgg gaacactttg accttgcttg tatccaattt caaggtaaat
     8101 cttaccacca tctttgagat agtcttttgc atcttccgca attctacagt aaatagctag
     8161 gccatcctcg tctgcaaaga gagctagatg aggctccgaa tgcaaaacat tcaagcctac
     8221 ctctgactca tcttcacgag agatataggg tggattggat acaattatat catatttttc
     8281 agaaatttct gcaaaacaat cagatttttt aaaaaatata ttaagatttt gattgctagc
     8341 attctctgat gcaagctcta aggcctcttg agaaacatct gctgctgtca ctgaccaatc
     8401 tggtctattt tttgctagag cgagagcaat agctccacta cctgttccaa tatccagaac
     8461 tgaaagattc gtctcaagat tttcagttag aataagctcc actaactcct ctgtttctgg
     8521 acgaggaatc aaaacccgtt catccacctt taaatgcatt ccataaaaat ctgcctgtcc
     8581 aatgatgtac tgagctggct tgtgagctgc tagttgctgg taaatatctt ctacaaattg
     8641 tttttcttcc tctgttgtca cctcctgctg gagggcaaaa ataaagtctg taaaagatag
     8701 atttttcaga ctacgataga caaaagagag gctttccgct tcctctcctt gtcttatcaa
     8761 ctcttcttca aaatttgaaa ataattgagc taatttcatt atttgtttaa ttcttttagt
     8821 ttttgtgttt ggtcataaag caccaaggca tccacaactt cgtccaattt accagacaaa
     8881 atcgtatcta gtttttggag ggtcaagccg atacggtggt ctgtgacacg gttttgtggg
     8941 aagttataag ttcggatccg ttctgaacgg tcaccagtac cgattgtcga cttacgctca
     9001 gcgtcttgtt catcctgagc aatctgagca aagtggtcag cgacgcgtgc acggataatc
     9061 ttcatagcct tctcgcggtt cttctgctgg gtacgttctt cctgcatctc aaccttgata
     9121 ttggttggca agtgaacgat acgaacggca gtcgcaacct tattgacgtt ctgtccacca
     9181 gcaccagagg cgtgatagat gtcgacacga aggtcttttg gatcaatgtc gtattcaacc
     9241 tcttcaactt ctggcataac aagaactgtc gctgtcgaag tatgaacacg gccttggctt
     9301 tctgtcacag gaacacgttg cacacggtgg gcacctgatt catacttaag cttagagtat
     9361 acagactgac ctgaaaccat agcaaccact tctttaaaac caccgacacc attcatagag
     9421 gcttccatga cttcaaagcg ccaaccttgg gcttccgcat acttttggta catagttagc
     9481 aaatctccag cgaaaagtgc cgcttcgtct ccaccagctg ctccacggat ttcaaggatg
     9541 atattcttgt catcgtttgg atcctttgga aggagcaaaa ttttcagttt ttcttcatat
     9601 tcttcttttt cagccttggc atctttgagt tcttgcttgg ccatttcttc caagtccgca
     9661 tctccgcctg attccttaat catctcttcg gcatcgacga tattttgaag gacttgttta
     9721 tactcacggt aggctattac ggtgtcacga ttggaagctt cttcttttga aagctccata
     9781 aaacgcttgg tgtctgaaac gacatcaggg tcactcagca attctcctag ttcttcataa
     9841 cggtcttcta cagcttgtag ttgatcatag atgttcattt tttctcctta tttctcaatt
     9901 gttaaatcat agattgctac tacttcattc tcggatattt ccccagtttc tttaaatcca
     9961 taactgagat aacaaaatct tgcctgttca ttttctggtt cataagacaa ccaaagttta
    10021 ttgcttaaac ctgctggcgc tgttcgaaca tagtctagta ctttatccat aattggttta
    10081 aaatatcctt gattttgaaa attcttatca atcataaaac aaaatagtaa ataatttcca
    10141 ctactaatta cgatcttttt atcataagct atcatcacaa aacctataat tacatcatta
    10201 tcataaactg ccaatggagc tacaaaatct ccatttttag tgtagacgta tgcttcagct
    10261 aaactaattg cgttggttgc aatgaattgt ttttgatatt ccttgacatc caaatttaaa
    10321 acatcaaaat aattttccat tgtaacatct cttagttcaa ttgtcatagt tttgctcctt
    10381 gttagaggtt atcattggcg caaaataatg tttacggcaa accgagatat aggtttcatt
    10441 accaccaatc tggatctgtt ctccatcgta aacgggcagt ccatcctgtg ttcgcaacac
    10501 catggtcgcc tttttcttgc aatactgaca gatggtcttg atttcgtcaa tcttgtctgc
    10561 taaaagcaag agatatttgg aaccttcgaa caattcattg cgaaagtcat ttttcaaacc
    10621 aaaagccatg atgggtatgt ctaactcgtc cacaacacga gctaggtcgt aaacatggtg
    10681 gcgtttaaga aactgggctt catcgaccaa aacacagtaa ggtttttctg gtaggtctcg
    10741 gatatagcca aagatatccg ttgtttcctc aatcgcaagg gcagggcgtt tcatgccaat
    10801 tcgactcgac acatagccaa caccgtcacg cgtatccaga gccgaggtca taatgacaac
    10861 accttttcct tgctcctcat agttataggc caccttgaga atctcgattg tctttccaga
    10921 gttcatggtc ccataacgat aatacaactg tgccatgttt cttgcttcac gtccatttct
    10981 aaatttttgc tacattctag tatatcataa ttttcttaag ctttaaacgg caaaatgtgg
    11041 taaaatagaa gaaatcaaaa actagtggag gaagctatta tgccatttgt acgcatcgat
    11101 ttatttgaag gacgcacgct cgagcaaaag aaagctcttg ctaaggaagt aacggaagcg
    11161 gttgttcgca acactggagc acctcaatct gctgtccatg tcatcatcaa cgacatgcca
    11221 gaaggaactt acttcccaca aggggaaatg cgtaccaaat aagctagctt aagcagaatt
    11281 gcttaggctt tttcaatctc caagtagcat tcattgaaga aatatcctaa atttgttaca
    11341 atttgaaaag aaacttggag aatttccaag aaaatagcta ttaattaaag gaaacattat
    11401 gattacacgt gaatttgata ccatcgctgc tatctctact ccactaggtg aaggggctat
    11461 tggtattgtc cgcctgagcg gaacagacag ttttgctatt gcgcaaaaga tttttaaagg
    11521 aaaagacttg aacaaggttg ccagccacac tctcaactac ggtcacatta ttgatcctct
    11581 gactggtaaa gtcatggacg aggttatggt tggggctatg aagtctccaa agaccttcac
    11641 tcgtgaggat attatcgaga ttaacaccca cggtggtatt gcggtgacca atgagattct
    11701 ccagctagct atccgtgaag gagctcggtt ggcagaacct ggtgaattta ccaaacgtgc
    11761 ctttttaaac ggtcgcgtag atttgacaca ggccgaggcg gtgatggata tcatccgcgc
    11821 caagacagac aaggccatga acatcgcggt caaacaactt gatggttccc tttctgatct
    11881 tatcaataat atccgtcaag aaatccttaa cacacttgcc caagttgagg tcaatatcga
    11941 ctatcctgag tatgacgatg ttgaggaagc cactactgct gttgtccgag agaagacaat
    12001 ggagtttgag caattactaa ccaagctcct taggacagca cgtcgtggta aaatccttcg
    12061 tgaaggaatt tcaacggcta tcattggacg tcccaacgtt gggaaatcaa gccttctcaa
    12121 caacctcttg cgtgaggaca aggctatcgt aaccgatatc gctgggacaa cacgagatgt
    12181 catcgaagag tacgtcaaca tcaatggtgt acctctcaaa ttgattgata cagctggtat
    12241 tcgtgaaacg gatgatatag tggaacaaat cggtgttgag cgttcgaaaa aagccctcaa
    12301 ggaagccaac ttggttctac tagtgctaaa tgccagtgaa ccactgactg cgcaagacag
    12361 acaacttctt gaaattagcc aagataccaa tcgcattatt ctacttaata aaaccgacct
    12421 gccagaaacg attgaaactt cgaaactacc tgaagacgtt atccgtattt cagtccttaa
    12481 aaaccaaaac atcgacaaga ttgaagagcg aatcaacaac ctcttctttg aaaatgctgg
    12541 cttgattgag caagatgcta cttacttgtc aaacgcccgt cacatttccc tgattgaaaa
    12601 agcagttgaa agcctacaag ccgttaatca aggtcttgag ctggggatgc cagttgattt
    12661 gcttcaagtt gacttgactc gtacttggga aatcctcgga gaaatcactg gggatgctgc
    12721 tccagatgaa ctcatcaccc aactctttag ccaattctgt ttaggaaaat aagaaaaatc
    12781 catgatcctt cattcggtca tggattttat tgtctttatt agtaatctgg tcttaagacc
    12841 cctgttacag ttgccttagt tgcttcgtag tcgccatcta cgacaacctt gataatgcgt
    12901 ttggcatctt cttctggtgc tggaacaaga ggtagacgag tgggtccagc ttcaaatccc
    12961 atatagttaa gaattgcctt aactggagca ggacttggat aagagaagag agcattaacc
    13021 ttaggaatga atttacgctg aattgctgcg gctttcttca tatcgctttc tgcaatggca
    13081 gtaaacatct cgtgcatttc atccccattt gtatgagagg caacagaaat aaccccatcc
    13141 gccccaaggt tcatggcatg gaaagcatct ccatcctcac ctgtataaat caagaactct
    13201 tcaggcttgt gctcaatcaa gtaagccata ttagccaagc tagtacattc tttgacaccg
    13261 ataatatttg gatggtcagc caagcgaagc atggtttctg gagtcaattc gacaactaca
    13321 cgccctggaa tgttatagat aataattggt aggtcagaag catctgcaat agtcttaaag
    13381 tgctgataca tcccttcttg agaaggtttg ttgtagtaag gaacaatagc aagcccagct
    13441 gcgaaaccac caaattccgc tacttctttg acaaactcaa tagagtcacg cgtatcatta
    13501 gtacctacac ccgcaatcaa aggaacgcgt ccattgacaa ccttttgtac agccgcaaac
    13561 aactccaact cctcatcgtg ggtcaaagtt ggactctcag cagtcgttcc tgcgagaaga
    13621 attccatccg tatgatgggc caataaatgc tcaatcaagg ctggaatagc atcaaagtta
    13681 atagaaccat cctcatgaaa gggggtaata aaggctgtaa tgattttaca ttcttttaaa
    13741 tcttgataag acatgaaaac acctctctat ttcaaagaag gagttcatct gaactcctaa
    13801 acgatatgac tattttaatt caaatttcaa ttcggctgtt ggacgaacca atccacgttc
    13861 atgaagagtt tcagcaatct gaactgagtt ccaagcagca cctttgagaa ggttatctga
    13921 aacaacccac atgtgaattc ctttttctgc atccaagtct ttacggatac gaccaacaaa
    13981 ggtatcacgc gaaccaactg cattgatagc ttgaggatag atttgatgag ctacatcatc
    14041 ttcaagaaca gcacctggga aggctgcgat agctgctttt acttcttcga ttggagccac
    14101 ttcttttgtt tcgatataaa cagactcaga gtgagctgac aagactggaa tacgcacaca
    14161 tgttgcagat actgcaatgc tatcatcttc cataattttc ttagtttcct tggtcatctt
    14221 catctcttcg tacgtgtaat cattatcagt gaaaacatca atttgtggaa gagcgttaaa
    14281 ggcgatagga taatgtttct tgtcaccacc tgaaggcaaa atttccgcat gcaaatcaca
    14341 tggtttcaca ccatcattca agacttcacg aagttcacgt tgtgtctcaa gaattgctcc
    14401 cataccagca cctgaaacgg cttgataagt tgaaacaatg atacggtcca agccccattt
    14461 ttggcgaacc ggctcaagag ccaccatcat ttggattgtt gaacaattag ggcaggcaat
    14521 gattccgttg tgggcatcaa gtgcatgagc attgacctct ggaacaacca aaggaacatc
    14581 tggattttga cggaaataag atgtattatc cactactacc acgccagctt ttactgcgta
    14641 tggtgcatac ttagctgatg tagaactacc tgctgaaaag agagcaatat caactccttc
    14701 aaaagctgtt tcagtcgttt cttcaattgt aatatcttga tctttaaatt tcaatgactt
    14761 acctgctgaa cgtgcagaag caaggtaacg gattttatcg attggaagtg ttgattcttc
    14821 caacattttt atcatctgag caccgacagc acctgtcgcg ccgactacag caactgtata
    14881 tcccataaat aacctctttc ggaattttct aaaaatttct ataatagaag tattatacta
    14941 ctttttccat gaattgcaaa gctttttcat cattttttgg aaaataaaaa tcccagtcgc
    15001 tagactaggg actaagaggc atcttcatgt gatgagcagg ttcacacaac tcatcaaggt
    15061 ccgctcctgc gttatgacct ccttatgctc aatagtagtc cgaagactac ctatcgactc
    15121 atcgcatatt ctatattact agagatactt gattttgtca ataagaaatt ttttcgatcg
    15181 agtataacaa aaaactctcg tattcaagag tttccctata catatcatgc taattgccgg
    15241 gatcgaaccg gcgacctcat ccttaccatg gatgcgctct gccaactgag ctaaatcagc
    15301 ttacttaaga agtatactat attcagaaaa acttgtcaag tttccttaga aattttccat
    15361 aggaaaaagc caggtaagaa ctacctagct tatcttcttc tatttactta aatcaattcg
    15421 acgaccaatt ttaccaataa taatcgcccc aataatcaat gaagcaaatt caccgattcc
    15481 tgttgtaaac caagtaagga agaatggtaa ttctgctaca atatttaact ctgcagcgat
    15541 agtaaacatg gaaattgaaa agaggattga aaagaagaaa tgatcttttt gaatcaatcc
    15601 gttaaagagg taatccttgc tatattttgc aaaaagccaa acacctaaac tgaggaatac
    15661 taaggttgaa ccaccaccaa caaagacatc tagcagtccg aagctaaaga aattagcaat
    15721 catacaaccg atggtaactc cgatgatgta cttaggattg taaaaagcca taaagttcat
    15781 catttctgaa atacgaaact gataagcacc atagctgatg gcatttaggg gcggtgtgac
    15841 agtcaaaacg acgtagatag cagcgacgat tgcaatatct gcaacatcac gaatagttaa
    15901 ttttttcatc ttttctcctt tggcggttgc ccgcgtgtaa tatgcttggt gaaagaagct
    15961 aagcaccaag ggttgcttta ttcaacccta ctagtatagc acaatagcct gctttatgct
    16021 atacttaaca catgaaaatt cctattcaaa aattttttaa caatgaaatc ttagcctatc
    16081 tcttttttgg ccttgcgaca actctagttt cgattctctc acgactagtc atttatcaac
    16141 taagtcatca ggaactcctg gctactgccc tagcaaatat tatcggtatc ctatttgcct
    16201 ttatcacaaa tgatacgatt gtatttaagc aaaaaaagaa aaatagactt atccgtttag
    16261 tgaaattttc tcttgctcgc ctttctactt ttctgttaga cttgttttta acttttctct
    16321 ttgtaaccca atttcctcac attatagggc aattcgtaac tgaaaacatt gataagataa
    16381 atgctattga aacaataatt gcacaaatat tcattattat catcaattat atattgagca
    16441 aggcctatat ttttagaaaa taatgctcca tttatgagcc ttttaattgc cttctataat
    16501 gatttaggat acaatgaaac acgaaacatt gaaaggaaaa cagtatgtta aaaaatctaa
    16561 aatcgttctt gcttcgagga aatgttattg accttgctgt cggtgttgta attgcctctg
    16621 cttttggtgc tatcgttact tcacttgtaa acgacattat cactcctctt attttaaatc
    16681 ccgctttgaa agctgctaaa gttgaacgta tcgctcaact ttcttggcat ggagtcggct
    16741 atggtaactt cttaagtgct attatcaatt ttatctttgt gggtaccgcc ctcttcttta
    16801 ttatcaaggg cattgaaaaa gcacagaaac tgactggcat aaagaaagaa aaaactgccg
    16861 aaaaaaaacc aaccgaattg gaagtccttc aagaaataaa agctctcctt gagaaaaaat
    16921 aatcgattaa aaggatctag cgcaaagcta aatccttttt tctttactct ttgggtaact
    16981 tgcctgcttt ttcaagcatt tttttgatca gataaggcat cttaacattc tcccgccctt
    17041 ttttctcaat cagttttttc acaaattctg gcatttgtaa atcttcagat tcagctaaaa
    17101 tgtttttcgt ctcgtctgaa ggaactaact catcaaaggt ctcttcttct gggagaaatt
    17161 ccttaaactc ttgattttca ttgactctaa ctgtattgac caaagcatca atcaaacgag
    17221 aatctgtatt tggcattggt ggacgatggt agtttacccc aaattcctgg cataagtcat
    17281 aacattctac atcattgtca aacaagacct caatatgctc actgatgaaa ctaataggta
    17341 caaaaatata atggtctgga tgttctgtct gttctctgag atactccaaa acatctggtt
    17401 taatccatgg aataccaata tcactctcac tctgccaagt gttggtatat tgttctgaac
    17461 tcaagcccag tttttcagcg actagcttgc tattttcgaa aatttggtct atataaggat
    17521 caccaaagtc caaggcaaaa atgggcacac tatgggctga aaagatgact ttaaagctgt
    17581 cttgctttac ttcttctttt aaaatcttag caatttcatc tgcccaatag tttaagagca
    17641 cttcttcctg ataccagtcc ttaatgacca aaaattgaat ttgtttgctt tctaaaaatt
    17701 tttcatagcc catgacagag tagaaagaat aatggggctc caaaatcaag cagatacatt
    17761 cttcaacacc atcagtttcc atctgcttga tcacgtctgg aataaaggga cgagaaaatt
    17821 tgttggcaaa gtagataccg tactcctccc ctaaacgttc tttgactaaa ttgacctcct
    17881 cacgtgtaat ccgctgcaaa ggcgtcccac cgatacgaat atagttgtca tagagagtct
    17941 ggatttcgtg gtcttggggt ctaactccac gacgaatgtt tgtaaagaat tctgctactc
    18001 cttcaaaact aatctcctct ggagatccaa aggtcatcat taatatggct tttttcatgt
    18061 tatcatcctt atgatattat tttctctatc cattctatca tgaaagaaaa aaatagtaaa
    18121 cgtttcctac gtctactatt tcttttgctc ttttgttttt ttatctcgtc ttataattag
    18181 gatgataagg acaagaagta agaggacgat aataaggagt agaaaggcta gaatgtaaat
    18241 ccaatgactg ggaattccgt gatcgaaata ccgtgttcct actgcttccc cactttcatc
    18301 ctgtgctact ttcaccggtg catccgttat tttagctaaa aggatatgtc gtccattagt
    18361 tatgttaagg aaacaggtgc ttaataaaac aatcttgtcc gttgaggtca aggaaacatc
    18421 tcgcttgtac ttggctttac ttagcagata ttgatagtaa gcctggtgtt cctcatcctt
    18481 ggaactcaag gttcgataaa tctccgtgtc ataggcatcc acttctaaaa tcccaaaaat
    18541 ttcaagacca cgttctcgac cattgtagta gatagaaccg tagcgatgct ggtcgaagaa
    18601 ttccttatca gcaaatttct taatctcacc gaacatagcc cctgaagcca tagagtgtcc
    18661 gtagatgatc gtattaaaat cagtaaagtt gggattaaag cgatagtcga gaaaaattga
    18721 tcccattatc gtataatcgc caaaggcatt gcggtcaagg tatttgacat tatcctgact
    18781 ttgtagaagc ggatagtcta ccttggtccc atcaaggcta atccaaccgc aaacatcttt
    18841 gttcaagtgc tgtagggttt caaaacctgt gctcgaagca tccttttcaa taggattata
    18901 gtgatcatag tcacttgctt ctactactct ctgccaacta aaaagagcta caaaaacaca
    18961 gaagaatacc agaaatacgt ttttaaatcg cgctcttttt tgaaccgtca tcagcactcc
    19021 tttctatgcg agatttctta aaaggaaagg aggcgggaca aaaccgcctc ttttctattc
    19081 acccttagtc agtaaaaggg tctgcttctt gcattttttt tactctctct tctacgacgt
    19141 aggatcaagt agaggacaag gagtaagaaa atcaagagca agaacaatac aaacaagata
    19201 aggtaccaaa tccatagtgg gattgatgag aggaaacgtc caagagacga gtcatcaaag
    19261 acactgtatg gaaatggttt tgattttttt gtatggaaag tatttttagg gacggtgtct
    19321 gtaatctttg cgactacgat atgacgacca ttggtcacat cgagaaaaca ggtactgagt
    19381 aggatgatac gatcactcgg tgagagtgag atatcccgct tgtgcatggc gactgagagc
    19441 aggtggtcta gataggcctg ctggcggtcc tcaccctgta ttcctggatc atagatgtta
    19501 aagtcatagg catcaacctc caacatctca aagatctcga gccctttttc cacaccattg
    19561 tagtatatac taccgtaacg atgctggtca aaaaattcct gatcagcaaa cttagccaca
    19621 tcaccaaaca tgaccccatt ttctacgtgg tgcccgtaga taatggtatt aaagtcttcg
    19681 aacttaggat tatttcgtgc atcgagaaag atagcgcctg tcgctgcaaa ctcacctttg
    19741 gagtccttgt tgagatactt ttcattgtcc ttggcttgga ctaagggata gtcgatattg
    19801 gtgccataga cattgatcca accgaggact tcgggattga gttcttggag tttgctgaag
    19861 cctgaaaaac tggccagctc atcctgttgc gtcgtgacag gtcgataagc ttcgtactca
    19921 cttgacgaag ctaaggagta gacttggttg gaatcccaaa gggcgtagaa accaaagaga
    19981 aagatcaaag ctgcaaaaat gagcagcaag tgattgatca ccccatccac agcaagaacg
    20041 agacgcctag acagactctt ttttggtttc tcacgcttgg ttttcatcat ctgcccccag
    20101 ccgtttaggc ttctctacgt tttttagaca agacaacaaa tccagccaaa ccaagaccaa
    20161 tcatcaaaat gaatggaagg ttatcaatca agagaccagt aggagtaacg tcgtcgattt
    20221 tgttagtaac tttgttgtcg tttttctttt cacctatgag gatatctgtt aatgtaaaat
    20281 ctacattttt ttgtccttga gatgtttgtt ctgcaccatt tgtagtataa attgatgaat
    20341 ctgtataacc tgctactcca gtttcagtta ctgtatattt agaacctgct ggtagttgtt
    20401 caactgtaaa tgtttcacca tctttaagag taaaattgta ctcaactgta tctgctgggg
    20461 tcactactgc caacacctct gacttagatc catgttttac tataatattc gtaacagggg
    20521 tttctgctgt tttatttgta cttggaagtt gaatcttgat atggaattgg aaatctcttg
    20581 ttttatcccc tgaagctcca tcaacttttt tagtaattgt taatgctttc gcattggggt
    20641 ctacttgact cggatcatca ggattaggct ccttacttgc gtctttggta tatgtgttat
    20701 caaataaatt ataaacgcct tgttcacttg gttctacttt aggggcgtta gatttattat
    20761 tttccttaaa gtatactgat gaaatataga caccaccatt tactttattc ttaacaataa
    20821 cgtgcatttc atatgtacgt ttgtcgtatc tcatggcatc aattgtttta ccatttttgg
    20881 taatcgcctg ccatccagtt tttgcttccg ctacatcata aacgtattca ccagcatggc
    20941 cataagcaac tcccgaaaaa atgtcttctg ttgctttttg aatcttatca gcagttgggt
    21001 gatcattttt attgtattct acatttctat ctggaattgc aactccggtt tgatatggcg
    21061 caccgttaga agattgtcct gttttttctg taaacttaaa tgtaaatgtc gctgttggtg
    21121 ttgttattcc ctctgcaata ttcaacgttt tattaatctt cacaacagca ttattttcac
    21181 catttgcttt ggttattgct gaattatcat ccgcaaaagt cgggacacct ctgaatacgg
    21241 acaaagcggt tatagctgca atgcttgcag tgaatagctt tttaaagaat gtttttttca
    21301 tgattatttc ttttgttttt ttattttctt ttttcattat gatcatcaaa agcctcgtct
    21361 tctaatgact gttacaactt tgccttgagt atcctgtata gggatggttc caaaagcacg
    21421 actgtctaca gccgttgttc gattgtcccc gaggacaaaa agttgtcctg ctgggacttt
    21481 catcgggaag gttgcccctt ccttatagag cagcgtttct ttgtagatat cttgctcttg
    21541 ttgaggagaa ccgttgatga tgagaccatt ttcgtttata tcgattgtac ttccttcggt
    21601 tgctatgaca cgcgccactc tttccttacc tttataacta tagactagca aatcaccaat
    21661 cgaatagcgt ttatccaacc tataatagac gaccaagtcg ccatctttta aggcgggctt
    21721 catgccatcg tcattgtatc ttaataatcc aaagacgaaa aagtaaagga tggctagtac
    21781 aaatccaacc atcagaagtt tactgactaa gtaaaggata tctccccaga cactcggcgg
    21841 agacttatcc cgattgactt gtgttactgg tttcttatgt ttctttttaa gcagcatcac
    21901 ttcctcctat tcaccacaag gtgaccaagt aagatgataa agaagatccc tcctagagga
    21961 agaacgactc caagcacgag agtgctactc aagaagtcaa ttcccgtttc aggtacgctg
    22021 tttttattat tcgtgactgt cgcagactta tttgcatcaa gagttccttc ttttttatca
    22081 taggacacct gatacccacg agacgaactt gcttcttctt cgatactata acgagcattt
    22141 agaggaaggt cgagaatctt gatggtttta tctttcttta gatcaactgt cgccttacca
    22201 ttggtgaatt gtagcgttgt tttttgatta tttactattg cactatacga tccattcaat
    22261 ggtttatttt gcgcatcctt tacgttaatg gtaatcttaa aggattgcag aagattagca
    22321 aaagcacctg taactttttt tatgactgaa agtgtcggaa gtctgtggtt ggtgacgatt
    22381 gtttgaacat cctctgacaa agtcccctct tgtttttcat aggtgacatg atatcccgtt
    22441 ctagagttct ctacttcttc caccttatag tgggtatcac gaggcagata actgagggca
    22501 gtttcctgac tatttttgag agaaatctgt gctttcccgt tagtcactgt tgtattccca
    22561 aacttgccgt taatcggctt gccatcctta tctgaaaggg taacattaat tgtgaaagat
    22621 ttattaggtg attgttcacc ttctaggatt ttctttacgg tgagacttgg aagctgtcgg
    22681 taaataactt tgaaggatgg tttctctttc gtacctgtct tttgaacttc gactgtgtat
    22741 cccggagcgt ctggtgcttt cagttcgtag tcatatccct tagctacctt tgcaaaacta
    22801 gtattttcag taaaactatt cgtttgaact ggactagtga cctttcgata ggaatccttt
    22861 atacttccat ctttcttttg gtttaagttt aattcgacac taggtggacg atttgctgat
    22921 ggatttgatt ttccatccac acctttccac tcaatctcta caggaaccgt caatggatct
    22981 gacggcttga aagtgggctt ctcagaatag tcttttattt tggtacgtga ggtcccaata
    23041 ccataggaat aggcaacttt tgcccccttg ttggagtaga gtttagtagc atcggcttct
    23101 tcggcatcat cactagtaag tgtcttatca cccgcaatcg catcaaatgc ctcttggcta
    23161 gaggtgacag taaacttgag aacgtacttg gcgtcatcct ctaaagtgta actcggatta
    23221 aacttggctg ttacttccac taatccctgt tcgttcttct tagtttcaat cgtaacttga
    23281 ttgtcattca gttcttgctc gttaccatcc ttgattttga cgacacgaag gtgtgaagca
    23341 tcaccaggta acagctgcac gtacttggac aagacatctg atatagttac atggtgtacg
    23401 cctagaggta gaattttatc tgtgatttct ttgaattttt gttgcaagtc attttcatta
    23461 ttggcagaaa atatttcgtt ggggattcca gaattataac cactgatata tcctttaaga
    23521 gatgtgatac tatcgtttga acctatatat ctgaatttga ttgaataaaa gccatctatt
    23581 tttggagcta ttaaactaga tatattcagc attcctctct ctaaaccaga ggtaaaccaa
    23641 tatggagtat caatcatacg tcccacattt ggattagaat aatagttata tattgttctc
    23701 ccactattag actcgtaata catattagct tcgccatctg acagcagaat aactactttt
    23761 tttgccccag cccttgcact ttgcaacaat ctttgagctt cagttaaccc agcatttata
    23821 tttgtcccag tgccaatgcc cgcgtccata ccataagaac gactagagtc agcaattgtt
    23881 aacgaactaa caatattttt tgagctatta gaatccgtgc tccaagatac taaagtttta
    23941 gcatcatcat atgaagagat atttgaatac caaccagctc aatttggcca agttccatat
    24001 tgataactca gataatattc attataataa cggtcattat actgattatc aatctttccg
    24061 gcaaaaccaa ctatagacag acggttttgg gaattagaaa gaattgtatc aatgagcccc
    24121 tgacgaccat tcacaccttt cagtgtatgt tttagtgctt caatcctact aatgtatcgt
    24181 ctactagagt aagaccacac atctcgctct tccatactcc ctgaaagatc ggcaaccaag
    24241 actacatcca agggttctga ctgggtctcc gttcccagtt tagatgtgat atccagtgac
    24301 aactcatact ggtctttttg ccctgatatc ggagtaatcg ttttgtgcag agttgtctga
    24361 ggttcagtta ttgaatctgc acgtaaagaa ttaattggtg cacacaaaaa aagaatagcg
    24421 agaaagataa ctaaaatact ggtaaaatat tgaatcttct taaaatcata ttgaacgttc
    24481 atgctatctc ccttgctaga atatgtttta atctgatact atataaatct gagacttcca
    24541 taagataatt gtataataat attaacttcg tgtcaattaa tgtgtttgaa aacatgttat
    24601 tataaattac aaaaaagtat gattcttctt tgtttttcaa ctttttctgt ggtaaaatgg
    24661 aaaaaatagt aaaaaatttc ataaaa
//
LOCUS       DAVKMJ010000032        24079 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000032 DAVKMJ010000000
VERSION     DAVKMJ010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24079
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.032"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(294..1901)
                     /locus_tag="VW348_001447"
     CDS             complement(294..1901)
                     /locus_tag="VW348_001447"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEU9746333.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDAEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENRN"
     gene            complement(2291..2878)
                     /locus_tag="VW348_001448"
     CDS             complement(2291..2878)
                     /locus_tag="VW348_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEU9746334.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(3006..3455)
                     /locus_tag="VW348_001449"
     CDS             complement(3006..3455)
                     /locus_tag="VW348_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9746335.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(3460..3849)
                     /locus_tag="VW348_001450"
     CDS             complement(3460..3849)
                     /locus_tag="VW348_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEU9746336.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETNQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(3877..4503)
                     /locus_tag="VW348_001451"
     CDS             complement(3877..4503)
                     /locus_tag="VW348_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEU9746337.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKNPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVFASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(4517..5080)
                     /locus_tag="VW348_001452"
     CDS             complement(4517..5080)
                     /locus_tag="VW348_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9746338.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(5245..5394)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(5454..5957)
                     /locus_tag="VW348_001453"
     CDS             complement(5454..5957)
                     /locus_tag="VW348_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEU9746339.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(6150..6980)
                     /locus_tag="VW348_001454"
     CDS             complement(6150..6980)
                     /locus_tag="VW348_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU9746340.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRLLV
                     LIAIFSVFLLYLSEIHFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGAYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(6965..8647)
                     /locus_tag="VW348_001455"
     CDS             complement(6965..8647)
                     /locus_tag="VW348_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9746341.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHCPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLRTELVKETPELQSLFRLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKALSSFIQTEGRYLWEGQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEQEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQQGHTIVMITHDMQLMLDYSDRALVMVDGELIA
                     DTDPASLLSNPELLVKANLKETSIFNLAKKLDVDPLALTAFYKERREGCKLN"
     gene            complement(8749..9006)
                     /locus_tag="VW348_001456"
     CDS             complement(8749..9006)
                     /locus_tag="VW348_001456"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746342.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVRQVS"
     gene            complement(9013..9561)
                     /locus_tag="VW348_001457"
     CDS             complement(9013..9561)
                     /locus_tag="VW348_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEU9746343.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(9576..10424)
                     /locus_tag="VW348_001458"
     CDS             complement(9576..10424)
                     /locus_tag="VW348_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEU9746344.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            10612..11961
                     /gene="trkA"
                     /locus_tag="VW348_001459"
     CDS             10612..11961
                     /gene="trkA"
                     /locus_tag="VW348_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEU9746345.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            11965..13404
                     /locus_tag="VW348_001460"
     CDS             11965..13404
                     /locus_tag="VW348_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU9746346.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRVKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMAFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMTIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLSLIFIVSLDSNDFLIVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(13529..15208)
                     /locus_tag="VW348_001461"
     CDS             complement(13529..15208)
                     /locus_tag="VW348_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU9746347.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGVIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSVMLAAICSYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QSISFVFLSLILVVDILIYLPFCRAYDRQLLMKEDVASSNDIILEEETSEIMPGELDE
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKNPSKALQFVLEHYQAV"
     gene            complement(15277..16689)
                     /gene="lacG"
                     /locus_tag="VW348_001462"
     CDS             complement(15277..16689)
                     /gene="lacG"
                     /locus_tag="VW348_001462"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU9746348.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGINMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVQYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGKVGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSDDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAPLNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            complement(16699..17043)
                     /locus_tag="VW348_001463"
     CDS             complement(16699..17043)
                     /locus_tag="VW348_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9746349.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            complement(17211..19097)
                     /locus_tag="VW348_001464"
     CDS             complement(17211..19097)
                     /locus_tag="VW348_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HEU9746350.1"
                     /translation="MVIRVFDQQKNTYSSFALEELRYYMNQVFNTDIELVEEKEADIF
                     VGLVNEEDGKDHIFISLNKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFIP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYKDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGQMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            complement(19099..20421)
                     /locus_tag="VW348_001465"
     CDS             complement(19099..20421)
                     /locus_tag="VW348_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9746351.1"
                     /translation="MNNILTFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEAFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRIFIQRGITIKMPNGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            20589..21812
                     /locus_tag="VW348_001466"
     CDS             20589..21812
                     /locus_tag="VW348_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU9746352.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPSVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTATKYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKKFDFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            22823..23107
                     /locus_tag="VW348_001467"
     CDS             22823..23107
                     /locus_tag="VW348_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746353.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDIEKL
                     LDSKELTHFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            23100..23657
                     /locus_tag="VW348_001468"
     CDS             23100..23657
                     /locus_tag="VW348_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter peripheral membrane
                     component"
                     /protein_id="HEU9746354.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVGGYVLEYHGLRATQDVD
                     AFYDQNQKINEIIARVGKQFNLNTHEELWLNNHVANMNKQPPLSLCESLYSFENLTVL
                     VVPIEYVLGMKMMSIREQDLKDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVLLEG
                     FSYAYGMDWLEKFFKENQDKLREFY"
BASE COUNT         7640 a         5183 c         4066 g         7190 t
ORIGIN      
        1 ttctataaat taatttgact tttctgatag agatgttcac atcttatttc aattcatgat
       61 acaatccagt tcctaaaact ttgctagaaa ttaatttggc tttccgaatt aatttgttca
      121 gattttattt catttcaata tactgataaa tccattcact agcacagggc aagagggagt
      181 cgctattgat ttcaacggta gcaggtacat acagaggact cctacctcag atatactgca
      241 atatcatcgt gtgcaaaaaa cctctgagat ttttctcaaa ggttctgatt ttgctaattt
      301 ctgttctcaa ccgctgcagt aacaaaggca gtgtagagtt cttctggtcg gtttggacgg
      361 cttgacagtt cagggtgata ctgacaagct acaaagaatt tattttcagg aatttccacg
      421 atttctacca aacgattgtc tggagaaact cctgaaaaga caaagcctgc tgcctcaaac
      481 tgctcacgga aggcgttatt aaactcataa cggtgacggt gacggcgttg caccacttct
      541 tgattgtgat aagcagcagc agccttagag ccacgtttca acttagacgg ataaagtccc
      601 aaacgaaggg ttccacccat atcctcaata tcaatctgat cacgcatgat atcaatgata
      661 gggtattttg tttctggtgc aagctctgca gaattggcac cttcaagacc taaaacgtga
      721 cgagcaaact cgatacatgt caactgcatt cccaagcaga ctcccaacat tggaacatca
      781 ttttcacgcg catagcggat ggcttggatt ttcccttctg taccacgttg accaaaacca
      841 cctggtacga tgatcccgtc tgcatcagac aagagttctg ctacattctc tgctgtcaca
      901 tcattggcat tgacccaatt gattttaact tctgcatcat tgacatagcc agagtgtttc
      961 aaggcttcga ccactgagat ataggcatct tgcaactcca catacttacc aacaagggaa
     1021 atcttaactt gtttcttgag gttcatgacc ttgtccacca tggctgacca ttctgtcata
     1081 tccgctgctg gtgcgtctaa tttcaaatga tcacaaacaa tttggtccat cccttgtgcc
     1141 tgcaagttca gtggaatttg gtaaagatgt tcaacatcca acgattcgat aacggcttct
     1201 ggtgccacat cacagaactg ggccagttta tttttaattc cttgaccagc tggctcttct
     1261 gtacgaataa ccaacatatt tggttggatt cccaagccac gcaattcttt gacagagtgt
     1321 tgggttggtt tggttttcat ttcaccagca gccttgaggt aaggaagcaa ggttgtatgg
     1381 atatacatga cattatccgc acccacatct gccttcatct gacgaagagc ctctaggaat
     1441 ggcaaggact cgatatctcc tactgttcca ccaacctctg tgataatgac atcagagtcg
     1501 gtcgttagag cggcacgctt gattttttct ttcaaagcat ctgtgatatg aggaatgact
     1561 tgaacagttg ccccaaggta ttctccacgg cgttctttac gaagaacttc actgtaaatt
     1621 ttcccagttg tcacgttgga atatttgttg agattgatat cgataaaacg ttcatagtga
     1681 cccaagtcca aatctgtctc agctccgtca tctgtcacaa aaacttcccc gtgctggtaa
     1741 ggactcatgg ttcccggatc aatattgata taagggtcaa acttttgaat ggttactttg
     1801 agaccacgat ttttcaagag acggcctaga ctcgctgcca caatcccttt cccaatggac
     1861 gataccacac caccagttac aaaaatatat ttcgtagaca tagattcctc tttctaaaat
     1921 gctcaaggtc ttgttaacta cgaggggata tagaaaacaa gaccctacta ataagaataa
     1981 tctgggacga ctgcaccaga ttcacaacta atactcttcg aaaatctctt caaaccgcgt
     2041 caacgtcgcc ttgccgtaga tatgtgttcc tgactttgtc agtcttatct acaacctcaa
     2101 aacagtgttt tgagcagcct acggctagtt tcctagcttg ctctttgatt ttcattgagt
     2161 ataaaataca agaagataac ttcttgaaaa aacaaaaata gctccctaag aactagggag
     2221 ccccgacctc taaaagaggt gcccaaacaa tatgatacct aaaaatagga taattgtcaa
     2281 tagctaactc ttattcctcg ctggtttcag cgtcgtcatc tgaaaactcg tcgtcgtctt
     2341 cgttgagatc cacatcttct cccaagtcat ctggagcgat ttcgttgatt tctgcatcat
     2401 aagcttccac ttcatttttt tcatcatctg gattttcatc atcgtatgaa agagctggat
     2461 ctgcttcgta tgcatcttcg tcttctggat catctgcatt gtagtcaatg gcatctgaat
     2521 caccatccat aaaggcattg acacgttttt tcttagcttt tggtgctact tcatcgtcgt
     2581 cattttcttc aagagcgatg atttcttcgt cgatttcgtc cacaccatac catgaacgaa
     2641 gaccccattt gttgtcccca agtgagatga agctaccgtc aaagttcaac tctgtgtaga
     2701 acaaaggcaa agcttcgcgg atatcgctgt ttgatgttcc aaggtagttt tgaatttcgt
     2761 ttacaagatc gctaaaatgc atctcatgat cgcgaccacg aagttccaag atagcacgcg
     2821 ctacctcaat catagatagt tcactttttt cttgcccagc aaatacttct aattccaaag
     2881 cgtttctcct catttatact actatcgcca gagcgaacag actctgacct cattttatca
     2941 tttactcttt attttacgat aattttgcgg aatagtcaaa ggttaagggg gagaaagtgg
     3001 caggattaga ctaattccaa tataaaactc cttccttttt ctgttgctcc attttccaca
     3061 aatccaagcg acttgaaaca cctcctagaa gcatgattgt aggtgtagat ttccttgact
     3121 ctcaattctt tccatccttt tactcgagcc aattcaatca aagcacttag aatctttttt
     3181 ccaagtcctc gatgttggta agcggaattc ccaatcacaa tggggagatt atcctgagat
     3241 agtgtaatat ccccaattgg aaaccattct cccttctcct tgacttcaat ccaaaaaagc
     3301 tcaccatgcc gatccaaata ggaatacatg gcttccaagg tcgcttgact gtaaggaagc
     3361 ttcaccccat ctacgaggta aaccaagttc acatcctgat accaagcaaa agcttcctca
     3421 caatgattga ccttataata aggaacaaaa cacaatgcac taccttttca acaaaagagt
     3481 tgctgcttga ttaaaaccat cacaccagtt ataccatttt gcttcatacc catcttgagc
     3541 taggatacga tcttctaaat caaaaacaga gtaaatcttt ctttcctcgc aagcttgcgc
     3601 atagagatga tatagttcat caccaccatc tctatcccac tcagcagaaa tcgtatcccg
     3661 acctgccaat aaagcctgat aagccctgtg atgcccatct gtaatcagca aacaatctcc
     3721 aaaggcaaga atactgattg gatcgacttg gtttgtttct gccgactggt aaagcatctg
     3781 aatatcttgc aacttctttt ctgataaata tagttgagtc ggatgaagat ctgctatatt
     3841 gactttcatt tctttctcct caagggaatt cgatactcac ttctgtttgc ctttaaatcg
     3901 ccattggaag cggagcttgt catagaaggg aaactcgata aacaggactc ccaagcccac
     3961 acagagactg gcaaagacgt ctgatgggta atgaaccccc agatagactc ttgataccag
     4021 cacactgact aggtagaggc caaggacgat ttgtacgatt tttctccaga ctggattttt
     4081 aattcgttga ctgagaatga caatcagagt acctaccatc aaagttacag ccagagaatg
     4141 tccacttggg aaggaaaatc ccttctcttc caccagatgt aagatagctg gtcgtgggcg
     4201 ctggtagata tttttaaagg tcacgattaa aagacctgcc aaagccagat ttcccagcat
     4261 gaagaaactt tctatcttcc atcgcttacg ataaaagaca aaagctgtaa tgacaaccca
     4321 agtgataatc actgggatat caatcagacg tgtgagggct cgaaaaagaa tagtcaaata
     4381 atctggtaag tctcctcgaa tggcagtctg aatcgattgg tcaaaattga ccaacatttc
     4441 agggtaaaat ttgaccatat agccaagaat aacgaaaagt aaaagggcaa aactgccctt
     4501 cattaaaaat gtttgtttat ctttcatagt gttttaaggt tggtttcaaa aggacgtaca
     4561 acaaccagaa tgaaacggaa aagattacac cctcaatcaa gttaaaaggt aataccatgg
     4621 tcattaggta gttggaaagt cccaaaattt ttccaatatc aaagttagca aacttagcgt
     4681 acaaaggaac agcataaaca tagttgagaa ccaacatggc caaggttaaa ccaacagttc
     4741 cagctagaga gcctagtagg aaacgaaggg ttgtccgttc ctttttccaa atcaaagcaa
     4801 atacgatgac aaaaactccc aaagctacga tattcatcgg caaaccaatg taagtattca
     4861 ctccttggct gttaagaagc aatttcaata gtgagcgaag caagagcact cctagagcag
     4921 caggcaaatc catgaccacc agacccacaa ggactggcaa gatactaaat tcgatcttga
     4981 ggaaagatgc cgctggtaaa agcggaaagt caaagtacat cagcacaaat gagatggctg
     5041 ataaaattgc aatggtcgaa agtcgacgtg tgtttgtcat aacaggttcc tccaattttc
     5101 tataaaatca gaagaagttg gaaaggattc ctctatctat tctcactttt tatatcccaa
     5161 aaattccctc ttactctatt aaagaaaaac aaagcaagtg gttacaatcc ggctataaat
     5221 ctatcaaaac agacaaagct attctttcgt cttctcccat ccagactata ctgtcggttg
     5281 tggaatctca ccacatcagc ttgcgctcgc ggacttcttt aaagagaagg aaaagatcat
     5341 ttcctagtta aagtcaccgc cggtcgggaa tcacaccctg ccctgaagac tcttttatca
     5401 taacaaaaaa cgcttgcaag cgcaagcatt ttgttcattt tcattttcat tttttatttc
     5461 aatttatcca cttcataggt atggacgagc tcaagacctg caaagttctg ctggcgaaga
     5521 gcctcataga caatcatgca gacggtatta gacacattga gactgcggac atgttcatca
     5581 ttcatgggaa tacggagagc cttctcagga tgttctcgca taaaatcttc aggtaagccc
     5641 ttgtcttcac gtccaaagag aaaataatgg tcctcgtcag tcgataaatc cacctcagaa
     5701 tagacttttt ctgcgaattt cgaaatcaga tagagttttc ccttcatctg agatatgaaa
     5761 tcttccaaac tctcgtaaaa ataaatctct agcttatccc agtaatccaa tccagcccgc
     5821 ttcatcttgc ggtcatcaat aggaaagccc ataggcttga tgatgtggag gggagaattg
     5881 gtcgcagcgc aagtacgcgc gatattgcct gtattttgtg gaatttgagg ttcaaataat
     5941 acaatgtgat ttgtcatgac ttgcttcctt tcaccattgc aaaaaaatag ccacactgcc
     6001 cggagtcaag ctcagcaaac agcgtggtta aggcatcgtt aacttacctc acaacaggtt
     6061 tgaagtaaat cagcgaaact actttcttag tataacactt tcagaatcat tgtcaataga
     6121 aatgacttga ttttttcaat tttttcaagc tatttccaag ggttgtaaaa tcgtccctga
     6181 ttctgcaaga taagtagtaa actaactact aaaaacaagg ttgccaagag caaggtaata
     6241 tagtctcctt ttttcaaggc ctgataacta taccatgtgc gttttttctc tttcccaaag
     6301 cggcgaagct ccatggcagt cgcaatggta tcaatgcgtt ctagcgagct aaaaatcaag
     6361 ggagtaataa tgagcagatt gcctttgatt cgttgcataa gagaagcttt cttggataat
     6421 tccatcccac gcgcttcctg agacatcttg atggtaaaga attcttcctg caaatctgga
     6481 atatagcgca aggttagact gacagaatag gcaatcttgt aaggcacacc aatttgattt
     6541 aaactggaag caaactgact agggtgggtt gtcatcaaaa agataatagc cagaggaata
     6601 gtgcaaaggt acttaatagc caaatttagc agataaaaga gctcttgact ggtcagagtg
     6661 taggcaccga ttccctgcca aatcacactt ctctctccgt aaagtccaac cccatactcg
     6721 ggagaaaaga gatagaccat caaaacgttt aaaacggcaa ataccgtcgc aaaaacggct
     6781 acaaaggaaa catctttaaa atggatttct gacaaataga ggagaaagac cgaaaagatg
     6841 gcaatcagaa caagcagtct ggtatcatag ctaatcatgg ccgccaatga cacgagaatg
     6901 aaaaagagga gtttcccagc gcctgacaag cgatgaatca cagtatctct atgctggtaa
     6961 ccgattaatt tagcttgcat ccttctctcc tttctttgta aaatgccgtt aaagcaagtg
     7021 gatccacgtc gagtttctta gccaagttga agatagaagt ctcttttagg ttggctttta
     7081 ctaacagctc aggattgctc aacagactag ctggatcagt atcagcaatc aattccccat
     7141 ccaccatgac aagggctcga tctgaataat ccagcatcaa ttgcatatca tgggtaatca
     7201 tgacaatggt atgcccttgt tgatgcagtt cttcgagaaa ttccataatc tcagtatagt
     7261 tcttctggtc ttgacccgca gtcggttcat ctaggaggat aatttcagcg cctaagacca
     7321 aaattgaggc aatagtcaca cgttttttct gaccaaatga cagggcagaa atgggccaat
     7381 tacggaattc atagagacca cagattttca aggtttcata gactctcgtt tcaatttcct
     7441 gctcgtccac acctcgcaaa cggagtccca gagccacctc atcaaaaatc atattggttg
     7501 aaatcatttg attgggattt tgcagcacat agcctactcg ttccgcccgc tctgcaacag
     7561 aatctccttt tatatcctgt ccttcccaaa gatagcggcc ttcagtctgg ataaagctac
     7621 tcaaggcctt ggctagagtt gacttccctg ctccattttt tccgacaatg gcaatctttt
     7681 cacccttttt aatatctaaa tgaagagatt ttaaaatcgg tctatcatca taagaaaacg
     7741 acacgtcctc tagtctaaag agtgactgca attctggggt ttcttttacc agttccgtcc
     7801 gcaactgaac ctgacctttt gagatagaca agttatccag atctgctaat tgttcttcct
     7861 tgactaaatc cacacccaat tgacggagag tggtgagata aaggggttcg cgaattccat
     7921 tttgggtcaa caaatcagtc gccagtaact ggtcagggct cccattaaaa aggatacgac
     7981 catcgtttat caagacaatc cgatccacag ggcaatgcag aacatcctcc aaacggtgct
     8041 cgataataag ggtcgtcgtc ccctcctcct tatgaatctg gtcaatcaat tcgataatat
     8101 cctgacctga cttgggatca agattggcga gtggctcatc aaacaagaga atcggacttt
     8161 catcaatcaa gacaccagcc agactgactc gctgcttttg tccacctgac aaatcctgag
     8221 ggcgctgatc cagtaaagga agaaggtcca gcttttcagc ccatttataa acacgacctt
     8281 tcatctcatc tagggctgtc acatcatttt ccagagcaaa cgccaaatct tctgccacag
     8341 acaagccaat aaactgccca tctgtatcct gcaaaactgt gctaaccaga tgagacttat
     8401 catagatgct catatcaaag gctgtttgac cctttatcaa aaattctcca tatgtctgac
     8461 ccttgtaaat attgggaata atcccattca aacactgacc caaggtagat ttacctgatc
     8521 cagatggtcc aacaattaag actttctctc ccttgtaaat ggtcaagtct atcccttgca
     8581 aggtcggttc ttgttgtgtt tcataccgga aagagaaatc cttccactca attatagctt
     8641 ctttcatctt actctcttca ttcgcttctt agacttctat tttatcataa atcaagccct
     8701 tcttgcagtc tcttctctta aaatcttagc gccaaaaaga ttcctatcct agcttacttg
     8761 cctaactaat ctataaacat cgaaaaagac tagttgccca gccttcccca tcattttata
     8821 ctcttcgaaa atctcttcaa accacgtcag cttcgccttg ccgtaggtat ggttactgac
     8881 ttcgtcagtt tcatctacaa cctcaaaacc atgttttgag ctgacttcgt cagttctatc
     8941 cacaatttca aaacactgtt ttgagcaacc tgcggctaac ttcctagttt gctctttgat
     9001 tttcattgag tattagtcct ttttcaaact tcctgcacga gtttgggttc ctgcataggc
     9061 aagtaagaga agagttcctg caatagctac agatacacca ttggcaattc ccgcaacaat
     9121 cccttgtgca aatacttttt ctgccgcttc ttgataaatc acaacatctc caagtggtgc
     9181 caagacaccc caaacaaggg catttgcaag tagttgaatg aggttaaaaa taagaatatc
     9241 tttccagtca aaaacaccat tgatcacgcg aacgtacttt ctaaaaagtc ccacaactaa
     9301 accaaagagt ccgctagcga taatccaagt ccaccataga ccataaccag caagagagtc
     9361 cttgattgca tgaccaatca acccgacaag caaaccgata atcggtccaa aaataataga
     9421 aagtagcgct tgtaccgcat actgaagctg gatgcttgta tttggaacag gggttggaat
     9481 gttgatcatc ccgatgacga caaagagggc agcgccaatt ccgacagcaa caacttgttt
     9541 aattgtaaat ttaatttcca tactattctc ctattttatc cttctatttt ctttatttca
     9601 atggtccaag atgaaccgac acctacatta taggccttgg caaaggaacc ttggttgata
     9661 gccaaaccta aacgatagag agagttgatg taaaggatgg gttgcccaat tctcacatct
     9721 gcaaatgatt tgccatagac aacctgattt tgatagacca gcatatcagc atgatagatg
     9781 gtcacttcaa aacgatcacc aaattctggt tccagcttgt aaaattcttc ccgtgtgata
     9841 gaggtccaaa gcgaaccgaa acgcacatcc agaatatcaa tggctccctt caccagatga
     9901 tcttctatga tggtcgctac gactggaagc tctacaatct gttccacact gagctctggc
     9961 cctacttcct caaaagtaat gtgaccactg gccagtttag caccagtata ggcatagaca
    10021 tcacgaccgt ggaaggtata agaatgctct gtgttttgac gcctattggc cacctcagaa
    10081 atctcacgaa tggctacaat gccaacgtgt ttcttgataa aggaaagcgt cccattatct
    10141 ggcgtgacaa tgtattgatt ttttgcagtc ttggcaacta cactcttacg tttcgaaccg
    10201 acacctggat cgacaaccga tacaaacgtc gttccctcag gccagtaatc caccgtctga
    10261 aagagacgat agctcccctc aaaaatatta taaggcgtga tatcgtgcgt caagtgatgg
    10321 atttttaagg ttggagactc ttctaaagcc actccaatca tagccgatac cgcaccatca
    10381 accagaccaa agtctgattg taataccagt aaattattat tcattttatc tccttgtata
    10441 tcctttatca taccatattt cagagaaagt cgctaatagc tatttcaatt ggttagggta
    10501 tagttttacc ttatagcgaa ttttcactaa aagctcttgt tattagctag taggtgcatt
    10561 ttttcttgaa aaagggtatg atagttacat catgaaaaag taggttttat tatgaaaatt
    10621 atccttgtcg gagggggaaa agttggtttt gccctctgtc gctccttggt tgcagaaaag
    10681 catgatgttt tgctgattga gcaagacgaa gctgttctca atcatattgt cagtcgcttt
    10741 gatatcattg gtatccttgg taacggggcc gattttgcca ttcttgagca agccagcgtc
    10801 caagattgtg atatctttat cgccctgact gagcacgatg aagtcaacat gattgcagca
    10861 gttctagcca agaaaatggg agctaaagaa actatcgttc gggtgcggaa ccctgaatat
    10921 tctaactctt atttcaagga aaagaatatt ctcggttttt ctcttatcgt taatcctgag
    10981 ctcttggctg cccgtgctat cgcgaatatc attgacttcc ccaacgccct gtctgtcgaa
    11041 cgctttgctg gtggacgcgt tagcctcatg gaatttgtcg tcaagtccac cagcggtctt
    11101 tgccaaatgc ccatttctga ttttcgtaaa aaatttggta atgtcattgt ctgtgcgata
    11161 gagagggatc atcaaattat cattccaagc ggtgacatga ctgtacagga taaagataga
    11221 atctttgtca ctggtaaccg tgtcgatatg atactcttcc ataattattt taaatcacgc
    11281 gccgtgaaga gccttctcat cgttggggca ggtagaattg cctattatct acttggtatt
    11341 ctcaaagata gtcgtatcga tacaaaagtc attgaaatca atcctgaaat cgccagcttc
    11401 tttagcgaga aattcccaaa tctctacatc gttcaaggag atggaaccgc aaaagatatc
    11461 ctgctggaag aaagtgctca acactatgat gccgttgcga ctctaacagg agtcgatgag
    11521 gaaaatctga ttacatctat gttccttgac agggtaggtg tacagaaaaa tattactaag
    11581 gtcaatcgta ccagtctcct cgagattatc aatgcgcctg atttttcaag tatcatcaca
    11641 cctaaaagca tcgctgtaga tacgattatg cactttattc gtggtcgagt taatgcccag
    11701 tattcagacc ttcaagccat gcaccatcta gccaatggcc aaattgaaac cctgcaattc
    11761 catatcaagg aagccaataa aatgactgcc aaacctcttt ctcaactgaa attgaaaaaa
    11821 ggggttctta ttgcagccat tattcgaaag ggcaagacta ttttcccaac tggggaggat
    11881 atgttggaag ttggagacaa gctcctagta acaaccttgt tgccaaacat caccaagatt
    11941 tatgacttga ttgcgaggta agaaatgaat aaaagtatga ttcgttacct cctttcaaag
    12001 ttacttttga ttgaagctgt tctcctcttg gttcctgtgg ctatcgctgt ctattaccgt
    12061 gaatcgagcc aagtctttac agccctcttt tcgaccatag ggattctcgt attgttaggc
    12121 ggttcaggga gtttacagaa gccaaaaaat caacggattt atgccaagga gggagtcttg
    12181 atcgttgccc tctgttggat cctttggtct ttctttggtg gtctcccctt tgtcttttct
    12241 gggcaaatcc ccagccttat tgatgccttt tttgagatta gttccggctt tacgactact
    12301 ggagcaagta ttttgaacga cgtttcagtt ctcagtcgtt ccctcctctt ctggcgaagt
    12361 tttacccact tgattggagg gatgggagtg cttgtttttg cacttgctat tatggacaat
    12421 gccaaaaata gccacctaga ggtgatgaag gctgaggttc caggtcctgt ttttggcaag
    12481 gttgtatcca aactaaaaaa cactgcccag attctctatc tcctttatct agctctcttc
    12541 tccctctttg tcatcatcta ttatctagct ggtatgcctc tctacgatag ttttgtcatt
    12601 gctatgggga cagcgggaac tggaggcttt accgtctata acgatggaat tgcccactat
    12661 ggtagctcac tgattaccta tctggttagt ataggagttt tggtttttgg ggtaaatttc
    12721 aatctctact actaccttat gctccgtcgg gttaaggcct tctttggaga tgaagagctt
    12781 cgggcttact tggtcatcgt gctggtttct acaggcttga ttagcctcaa tactctctac
    12841 ctctacccag gattttccaa aagctttgaa atggccttct tccaggtttc caacatcatt
    12901 acaacaactg gttttggata tggagatatt accaactggc ccctcttctc ccagtttatc
    12961 ctcctcttcc tcatgacaat cggtggttct gctggatcaa ctgcaggtgg actcaagatt
    13021 attcgaggcc tcatcctttc aaaaattgcc aaaaatcaaa ttttgtccat tctatctccc
    13081 caccgtgttt tgactctcca tgtgaataaa acggtgattg ataaggatac ccagcataaa
    13141 attctcaagt actttgtcat ctatgctatg attttgctat cccttatctt tattgtcagc
    13201 ctagatagca atgattttct gatcgtgacc agcgctgtct ttagctgttt caataatatc
    13261 gggcctattc taggaaccac ttctagtttc tcaatcttta gtcctatctc aaaaattctc
    13321 ctctcctttg caatgattgc aggccgcttg gagatttacc caatcctcct tctctttatg
    13381 aagagaactt ggtctaagag ataaaataca aaatccctct ttttacaatt gtgaaagagg
    13441 gatttttata ttaaaaaggg ggaacgtttt taaatccaag cctgtctgta agcaaagtcc
    13501 ttactcaaat aaaagatgga aaaacttact acacagcttg gtaatgctcc aatacaaatt
    13561 gtaaggcttt acttggattc tttgttaaat gaatatattc cattcctctg gtagcaacta
    13621 tctgaatacc taatctttct gcatccacct tcatctctct ataataactc cgaacttgtg
    13681 gagccagaat aattaaatca taaacaccca taatatcata atgagctccg tacgctcctg
    13741 aattcgcaat cactctaact tctgctaatt gagcgccctc gttaattgca ttggctaatt
    13801 gcgcacttgt tccagaccct gcacaaagaa ccagtacttt caactcctta ctttttattt
    13861 catctaactc accaggcatt atttcacttg tctcctcctc taaaataata tcatttgagc
    13921 ttgcaacatc ttctttcatc agtaactgtc tatcatacgc tctacagaat ggcaaataaa
    13981 tcaatatgtc gacaactaaa atcaaagata aaaatacaaa ggagatagat tgaaaattcg
    14041 ttccaattaa caatcccaag ggaccaggaa aggcccaagg taactggata taaaatccat
    14101 tcattccaaa gaaatcaata aagacctttc ctagaaatac attcactggt ggagtcatca
    14161 aaaaaggtac aaaaagatag ggattcaaaa taactggcat accaaataga agaggttcat
    14221 tcaccgcaaa taaaacagga gtaattgtag ctttacctac cgattttaat tgtttagacc
    14281 gcataaagaa aatcaaaata aatggtacaa caaaggtagc ccccgttcct ccgatagcag
    14341 cgatataatt tccgaaatta ggcgttaaag aatgataagg aaactgccca tttgcaagaa
    14401 gttgagcatt ctcttccata ttgctcagtt gtaaagctgt aacagcaggt aagacaatag
    14461 atggtccatg aattccaaca aaccaaagca aagcgcacat aaaccaaatc aacatcatag
    14521 caggatatga ttctgccccc ttaaaaatag gagtcaatag ttgttgaaat acttgggcaa
    14581 aaggaacatc taaactaaac cgagatacaa tatctaacaa accactaata agtaaaacaa
    14641 aagaaaaagg aaaaatatct ctaaaagctt gtgatatagc cccaggaact tccttaggta
    14701 aatgaatagt aatgtctcgc ttaatacaga atcggtaaac atttacagta ataaaggcac
    14761 tgacaaacga agttatcaat ccttgagatc ctaaatagtt tgtcgacaaa cttgtagatc
    14821 ccgtcttctc atcaactaca agcgttacag ttaataccag ataactacat atggctgcca
    14881 acattacaga agtatcattt attacctttc caggaggcat ttttctatta acatttccag
    14941 ccaatgactt tgcaactgtc cctgaaacaa taacacccaa aactcccatg gttagcatat
    15001 acactttcct catccaggca atagctggac tcggtaactc tactccgaaa tttttaggaa
    15061 tcataataat aatcatcaaa aagcttgaaa acataattaa aggcatagta gcaatgaatc
    15121 catctttaat agccatcata taattattag tagaaatttt ttcaaatttc ccttgttgct
    15181 tttcaatggc agcgactagc ttatccataa aactcctcct ataaaaaatt caacctcata
    15241 tttaaaacat attaaacatc attcaaatcg ctaaccttaa ttccgtttta gcccttttac
    15301 ccaaagagca cttttcttaa tatatcgctt ctgtgtctca taatcaacaa agaaaagacc
    15361 atatcgctta ttgtagccat tcgcccaaga aaattgatct tgcaaagacc atataaaata
    15421 tccttgaata ttgactcccc tatctcgagc ctctaaaact ttgtgtaaat gttgctcaat
    15481 ataacggatt ctcttactgt catcaataat atcattctcg ccctctggct taacctcttt
    15541 aagggctgta ccattttcag ttaaataaat gacaggatgt tgaggatatt cttctttgat
    15601 acgaagtaac atatcaaata agccttgagg ataaatattc caatcccaat ctgttgtcgg
    15661 aataccaggc ttttttacaa attcacctag agcatttaat ttaaaagagg actgtccttt
    15721 tattcctgtt gaattaaatt cttgtctatt ttcacctttg tattcacgaa taaattctga
    15781 acgataataa ttcatcccaa acatcgtatt aagaggtgca gctcttttca taatttctaa
    15841 atcaccatct tcaataataa agctagaatt attagcttcc aatatttgat ttaagtgaaa
    15901 aagcgtgtca tcactgtagt agcccaaaaa agttccatct aatagaaatt tattattata
    15961 aacatcatac cgtttagctg ccaaaatatt ttctttttgc ccatcaatag gatagcctgg
    16021 ctttaaagca tgaatacaac ctacctttcc ctcaatccct aattgatgaa attcgaggac
    16081 tgcaagagca tgcgccaaca acatattatg attcgcttga attgcttcag ataattgaaa
    16141 atgatgattc ggaggaaact gacctcctat atattgacct gcagcaagag acatcagttc
    16201 attgattgta aaccaatgct tgacttctgt aaattcttgg aaacaaaagc gagcatatcg
    16261 tatgaaacga tcaatattct ctctattcaa ccaatcccct gtttctaaca ttttctgagg
    16321 cgaatcaaaa tgatgtaaag aaacaaacgg aatcacatta tgttttaagc aggactgaaa
    16381 gactctatgg taatactgaa cagccaatat attcggctcc ccatctatat caggaaatat
    16441 gcgaacccaa gaaatagata aacgcaaagc ctgcaaacca tgttctgccg ccaaggctat
    16501 atcttcttcg taacgataat aaaaatcact agctggatct ggtaagaacg gactattttc
    16561 ttgcaaataa acatcccaca tatttattcc tttgccatct accctagttg caccctctac
    16621 ttgataagca gcggtagcag ctcctaataa aaactccttc ggtaaggctt taacctgtaa
    16681 attttccatg actaatcctc attgcaaacc aatatgttct tcaatctttc gaattcgttc
    16741 atattcatca ataaaaaact ttacctgatc atacaatagc atcgttgtca tcaaagtatc
    16801 ttgaccatga atcatgataa aactcacttc aaaattatct ccagatgcct cctccgctaa
    16861 taaattagtc tgttctcgat gggcagacac tattgagtcg tttgcagact caaccaattc
    16921 tcttgcctgt tcaaaatatc catctctcgc aaacgccaaa gcatccatca aatctgacct
    16981 tgcatctcct gcgtaagcga caattgtaaa accaagcata tttatttctt cttttgattt
    17041 catctttctt cctcctcaat cttgatacat cttttacaca tcattattaa aatgacttcg
    17101 ctacgataca aatagaaagt tgaccctaaa tatcttaaaa atccttaaat ttcataatat
    17161 ttaggatcaa tcttctctga ataccttagt tcattttcta tacttataat ttataagtgg
    17221 aaaccagcgt aattttttgc tacttcaatt acacgataaa catccaaatt agattggaat
    17281 agcaattcgt gaccacggat ataattcaaa acatttctcc attcatcttg agcttgcctt
    17341 gtttttccag ttgcttgaag atataaagcc ttcgccatct taacaacata ttcacgatga
    17401 taactgagct gtttccattc atccttttga ctatttaata acttagaaat attttcctca
    17461 ataattggta aaaaattatc agctagattg taagctatat aataatgatt cgctaaaaca
    17521 tcattttgac ggctgccaat tgcattaaaa taatcacatg aggaataact agataatttt
    17581 tctaaatatt caacaacaga ctgccaattt gacccataca aagcagaaaa gtattcttca
    17641 atcaattctt cataacttct tgtcttcttc cagagcattt gccccataac ataattagga
    17701 aaattatgag ggaatccggc acgtaattct tgacacgaaa tgtacccgtt caaatgtagg
    17761 tttgaaagat aagatacatc tttgtaaata gtttgactaa ttttcatata gcctaaatcg
    17821 ccataatgag cacgccctaa aggatagtca tatacgaaac tatctccttt aaatgttttt
    17881 tgccactcaa aaagataaga taaattttct tcaagagaat tcggaagtat aattttatta
    17941 cgcagataag gtttaggcgt aggtatggaa ttgtcaaaat ctacatctgc ataactcatt
    18001 tcaaatgttc ttgtaatcgg tgcaaacatc atggtaaagc gttcaggatt atctaatttt
    18061 tctttctgag gcgcccataa caactcatgg taaagtagga aacaaatctt tgtatctaat
    18121 ccctcactcg ttaaagccct atccaattga ttgagaatac gaatatactg atccgaaacc
    18181 aattcttgtc tacagttttc gcattcacaa atattattac gagcatccga caaccataca
    18241 tgtaagtagt taacatcagg tcttttcttg gcataatcct taataatttc taccatctta
    18301 tcagctacat ctggatttga aaaatccagg ctggttaaaa tcggagccgt attaaacaat
    18361 tctcgtttcc cgtttatttc agcgacatag ggtttcttct cctctgaaat actaagacct
    18421 gattcccagc caaattttga agagtaacct aaaacctcac ctgtccatcc atgaccaaca
    18481 cgatgatgaa taagacctct tttttgcaat tctttatcca acctatcact caattcttgt
    18541 actaattcat ttgagaattt ttctttattt aggtatggat taaactcatg ttcataccaa
    18601 cgtttcaaaa aagaataggg attttcaaac tgaatgaaaa aactgttcat cccaatctta
    18661 ggtagccaat caatgaaatc tagtatattt tcaaatgaat ctgctccctc tatacatact
    18721 cccctatgat agtaacttgc tgtttcatct atagatagct ctttatctaa aaaatcttca
    18781 aatcttaact ctggaataaa gtcatgtccg cgccctggtc tagtatacac aacaccaaat
    18841 tcatgaaaca ttcggtaaat tccaataagt aaacctacaa ttgtattgga ctcaattctc
    18901 cccttacctt tgtttaatga gatgaaaata tggtcttttc catcctcttc attgactaat
    18961 cctacaaaaa tatccgcttc cttctcctcg acaagttcta tatcggtatt aaatacctga
    19021 ttcatatagt atcttaattc ctctaaggca aagctagaat aagtattttt ctgttgatca
    19081 aatactctga taaccatctt atttccctcc aacagtagct ttttcttttt caagattgcg
    19141 tttatctgca attttgaaga atggataata aattgctaca gaaaccaaaa tcaaaacaac
    19201 ttgtaataga gctcctcgcc aactagcccc tgtcgcaagg aagcctccta tgataggtgg
    19261 cattgtccac ggaaggatta cacctgttgt atagggtact aagcctacag ccattgatac
    19321 ataggtaatc aaggcattga ttgtaggagt agcaataaac ggaatcagca taataggatt
    19381 taaaaccgtt ggaaacgtaa atagaatagc tgtattgata ttaaagatag acggtataat
    19441 agctagctta cctaatgttt tattagcacg actcttacta aataggaaga gacaaatcgc
    19501 aagaccaata gtcgctccac cgccaccaat aaatacaaat aaatctttaa acggtaatgt
    19561 aataatgtgt tgtagggttt gtcctgcagc cacagcttct tggttttctg tagtaaattg
    19621 taaccaaact gggtctacaa aagcatttaa aacttgtccc ccattaactc cacagaacca
    19681 aaagaatgag tttacaataa cacataaaat catacctgga agtgttcctg caattaactt
    19741 aagcggcgtt ccaacaattg cacctaaaag tccgttgaga cctcctgcaa ctcctgctgc
    19801 ttccagacct tttaagacca aagcccacaa aacaaaagta gtaaaaccag gtaaaagagc
    19861 tgaaaatgat ttactgacca catctgggac accatttggc atttttatcg taattccgcg
    19921 ttggataaaa atacgataaa tctccgctgt aaccaatcca atggtaatcg ccataaacaa
    19981 agaagacgca ttcaggctag aaaatggtat tgcacctcca aataactgct tgacctgctc
    20041 cccattttta tcataaacca tacttgaaaa acgaggggcc atcaatacaa aactggataa
    20101 ggctatgatc cctgcagacg gaccatctgt accatatcct tccgacaacc tgtaggcaat
    20161 accgaaacaa gcgaccaagg agataatcgc tactgttgac tgattcatag ttgtcaagat
    20221 acttagcaat ccaacactat tcagccaatt tgtaaaagcc tcttgaggcc aactgattag
    20281 aataagaaat aaagagccga ctaaaatcaa aggcattgcc atcataaatc cttcacgaat
    20341 agctttcaaa tgccgttgat tgccaacttt ttcaccaaac ggagcgactt tcgtttctaa
    20401 aaacgttaaa atattgttca tcaccggaac tccttttttt attttttata aattaaatat
    20461 accactaaca gaaagcgttg tcaatatatt ttttactgtt tttacaatat ttttttcttt
    20521 gtatagaata ataattttaa ttgatttttt cttatgttta atataaaata aaccaaagga
    20581 ggaaacaaat gattacaaaa caatcagcct ttttacaaaa tagagccact atactggaat
    20641 ttctatatcg aaatccagca acatcccgta cagatattgt taatgaaaca ggacttactc
    20701 cagcaacaac gactaacatc ataaaagagc taagcgaaca atccctcata tacgaaactg
    20761 gtgatgaatt tagcgagttt tccggatctg gaagacgtag aaaaactatt tctattacag
    20821 ataatatccc atctgttgtt ggaggtattg aaataaacgt cttaggtatc tttctcagtc
    20881 tatgtgactt acaagggaaa actcttttcg agacagaaat tttgaatgaa gattatccta
    20941 tttcagaaat caattccacc attaccaata tgataaaaac agctacaaag tatgtccctt
    21001 tggagacaaa attacttgga tttggcttat caatacctgg acattataac aaagactccg
    21061 gaagcatcat tacaaacaac cccatatggg aatcatttaa tttattaaat gtaattaaaa
    21121 aattcgattt cccttttatt gtaaaaaata atatcgattg tatggctata ggacaatacc
    21181 tttttaaccc acacaatacc cccgataact ttattttcct acacgctgga ttaggtattt
    21241 acacttcctt tttcacaaaa gaaaaaatag gagcctctaa aaatccttat atcggagaaa
    21301 ttggacacac cattgtcgaa ttaaatgggc aatattgtga atgcggaaaa aaaggttgtt
    21361 tacaaacata tatttcggat gcttggttaa tcaaacatgc ccaattatta tttaaaaatt
    21421 ctcaactaac tgtactaaaa agccttgtaa agactgaaaa agacattcat ttagataccc
    21481 ttttaacagc ttacaactta ggcgactctg ctttacgcca acaaattgat aaaggagtca
    21541 atttattggc cacttctatt gcaaatcttc tcctcatcaa tcctgctgat aaaatctata
    21601 tcaacagtca attgcttaat tatcaacctt tcactcatga agtcagggat aaaatccaag
    21661 atcagctcca cttcgttccc tttactcgta atatagaaat tgaaatttta ccttacaaca
    21721 aacatcgtgg aagtatagga gcttgtgcat tagctatcgt tgcttttttc atagagcata
    21781 gcaatgtatt acaagatatt atttcacctt aatatattag aaatctatag acctgtttaa
    21841 atcaactata acctgtagta aatatctcgt atttagacaa tatgaaaaca agacgacttc
    21901 catataggaa accgccttct cgctatgctg catgaaactg taaaaataga tgaaagtgat
    21961 agcggtagtc aaatcaagag gcatcataac tctaaaaagt cacaatatat aagttcatcc
    22021 tcagaaaaat atcattctaa ttattgaaat gcctacatga aaagaaacgt taaatgctca
    22081 taaaacaagg aatacaggta tcaaaactgt gacaaaacaa gtccctaaat ttactaaaga
    22141 cactactcaa ctttacacct gtaaatggtt gttgtataat aaagttacaa agatgtacga
    22201 ccacactgtt gtaaatcata gtgttcgcga atatattact gatagcattt ctacaaatac
    22261 aagtaaaggg attggatgag attcaaacga aatatgtcag tgttttggca ttcctagcct
    22321 tcatatcatt taaagaattg tatagataaa atttttccca atacagacac tcgtaacaac
    22381 tgcttcattt ttctaccaac atatttagga acaggataag atacaagagg atcaatccat
    22441 aaatcagttc tataccaatc taagacaaat aagctaaaaa aacgattgat aataagcaaa
    22501 tagattccaa attttctcta tctgctcatt ttaataaaca atactagtgt aactatcctt
    22561 ccagtcagaa gcttgtcaaa tcacaccgaa aattcttcta aaatttatct cgttaggcaa
    22621 tcaagcaaaa actcaacgat agtacaaaca ttatcataca ggattgactt cctaaattat
    22681 atactttagt aaggtttttg gataagaaaa aaggttcatt ttacatttct aaacactctt
    22741 ttctaatacg agataattaa aaaaactaca tttttaaata taaactacaa taaaataaac
    22801 taaatgccat aggagaaaga caatggattg gtacgattat atgatacagg catccaaaca
    22861 atcacaattc aacgcaagcc attggtttcg ctatttgcga aaagttattt ttgaagacta
    22921 ttcttattta acaaaccaag atatagaaaa gttgctagac tccaaagaac taacccattt
    22981 tcaaaaaatt agcttgaagt atgcctttca agagcatact ccaactcata aatatgtgat
    23041 ttcattaaat aaacctgcta agttaaccaa tgttcaaaaa ttgatggaga aatacaagca
    23101 tggataaaat gaaaccggtc ttccaagcac taaataagga attaattcag gaaaatctga
    23161 ctttaacaat tatctgtgtc ggtggttatg tcttagaata tcatggtttg cgtgccacac
    23221 aagatgttga tgctttttat gaccaaaatc agaaaatcaa tgaaattatt gctcgtgtag
    23281 gaaaacagtt taatcttaac acccacgaag agttatggct caacaatcat gttgcaaata
    23341 tgaacaaaca acctccctta agtttatgcg aatccttgta ctcatttgag aatctgaccg
    23401 ttttagtagt ccctattgag tatgtgttag gaatgaagat gatgagtatc agagagcagg
    23461 atttgaaaga tattggtgca attattaaat acaaaaactt tcattcacca ttcgatacct
    23521 ttaaatattt aaaagacatg ggatttgata ctattgacct ctctgttcta ttagaaggtt
    23581 ttagttatgc ttatggtatg gattggttag aaaaattttt taaagaaaat caagataaac
    23641 ttcgcgaatt ttattaacag tatcaaacaa gatgattgtc aattagccag tcgtcttgtt
    23701 tttatgatga aatgaaataa aatcggaaca aatcacttag agaattccag tcaatttcta
    23761 gcactgtttg agacgtttca gcggactata gcaaaatgaa ataagaatag gacaaatcga
    23821 tcaggacagt caaatcgatt tctaagaatg ttttagaagt aaaggtgtac tattctactt
    23881 tcaatctatt atatttcaga ttcggtccac tattccttcc caaaaacatt gcatattgcg
    23941 ccgaaggaat tgctcatact atcccaagca caaaaccctc agtcgtttga ccgagggttc
    24001 ctttttatta ttcaagaact tgaggctcta taatatttgt agtgggtaaa tcccctatgg
    24061 atattatgga gcctatttt
//
LOCUS       DAVKMJ010000033        24032 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000033 DAVKMJ010000000
VERSION     DAVKMJ010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24032
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.033"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            51..200
                     /gene="blpO"
                     /locus_tag="VW348_001469"
     CDS             51..200
                     /gene="blpO"
                     /locus_tag="VW348_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEU9746355.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            304..423
                     /locus_tag="VW348_001470"
     CDS             304..423
                     /locus_tag="VW348_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEU9746356.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            892..1263
                     /locus_tag="VW348_001471"
     CDS             892..1263
                     /locus_tag="VW348_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746357.1"
                     /translation="MIKKNHILCEIVPGAVAFACFYLSISISSVFQFLLVVINLASIL
                     VTVYLTREMRIKEFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQLIAYI
                     GAILCLIIMLLLIWGLKYYKK"
     gene            1892..2275
                     /locus_tag="VW348_001472"
     CDS             1892..2275
                     /locus_tag="VW348_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEU9746358.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            2327..3016
                     /locus_tag="VW348_001473"
     CDS             2327..3016
                     /locus_tag="VW348_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9746359.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            3058..3291
                     /locus_tag="VW348_001474"
     CDS             3058..3291
                     /locus_tag="VW348_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746360.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            3442..4053
                     /locus_tag="VW348_001475"
     CDS             3442..4053
                     /locus_tag="VW348_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEU9746361.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            4214..5008
                     /locus_tag="VW348_001476"
     CDS             4214..5008
                     /locus_tag="VW348_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEU9746362.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5005..5640
                     /gene="trmB"
                     /locus_tag="VW348_001477"
     CDS             5005..5640
                     /gene="trmB"
                     /locus_tag="VW348_001477"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEU9746363.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQDPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            5766..6245
                     /gene="rimP"
                     /locus_tag="VW348_001478"
     CDS             5766..6245
                     /gene="rimP"
                     /locus_tag="VW348_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEU9746364.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMGKTRKKTVQIPYSLVSKARLAVKL"
     gene            6289..7425
                     /gene="nusA"
                     /locus_tag="VW348_001479"
     CDS             6289..7425
                     /gene="nusA"
                     /locus_tag="VW348_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEU9746365.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            7447..7740
                     /locus_tag="VW348_001480"
     CDS             7447..7740
                     /locus_tag="VW348_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEU9746366.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            7733..8032
                     /locus_tag="VW348_001481"
     CDS             7733..8032
                     /locus_tag="VW348_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEU9746367.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8049..10841
                     /gene="infB"
                     /locus_tag="VW348_001482"
     CDS             8049..10841
                     /gene="infB"
                     /locus_tag="VW348_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEU9746368.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKTEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11092..11442
                     /gene="rbfA"
                     /locus_tag="VW348_001483"
     CDS             11092..11442
                     /gene="rbfA"
                     /locus_tag="VW348_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEU9746369.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            11722..12501
                     /locus_tag="VW348_001484"
     CDS             11722..12501
                     /locus_tag="VW348_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746370.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYAF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
     gene            12503..12685
                     /locus_tag="VW348_001485"
     CDS             12503..12685
                     /locus_tag="VW348_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746371.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKADHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(13026..13103)
                     /locus_tag="VW348_001486"
                     /pseudo
     CDS             complement(13026..13103)
                     /locus_tag="VW348_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            13134..13367
                     /locus_tag="VW348_001487"
     CDS             13134..13367
                     /locus_tag="VW348_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEU9746372.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            13367..14701
                     /locus_tag="VW348_001488"
     CDS             13367..14701
                     /locus_tag="VW348_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEU9746373.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYEYMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKDDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            14711..14965
                     /locus_tag="VW348_001489"
     CDS             14711..14965
                     /locus_tag="VW348_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEU9746374.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            15061..15456
                     /locus_tag="VW348_001490"
     CDS             15061..15456
                     /locus_tag="VW348_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU9746375.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQPAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            15868..16316
                     /locus_tag="VW348_001491"
                     /pseudo
     CDS             15868..16316
                     /locus_tag="VW348_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
     gene            16303..16863
                     /locus_tag="VW348_001492"
     CDS             16303..16863
                     /locus_tag="VW348_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9746376.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHIFPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSKRVAEKLDFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            16863..17441
                     /locus_tag="VW348_001493"
     CDS             16863..17441
                     /locus_tag="VW348_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU9746377.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQSLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKYKPLKRHIEVSEREIIETAEILQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            17434..20085
                     /locus_tag="VW348_001494"
     CDS             17434..20085
                     /locus_tag="VW348_001494"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEU9746378.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVIAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNGGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHSIMPFVTEEIFGQYAEGSIVTAAYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     EKDKQADYQAKYDATVARIDEMKKLVK"
     gene            20166..20330
                     /locus_tag="VW348_001495"
     CDS             20166..20330
                     /locus_tag="VW348_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEU9746379.1"
                     /translation="MGKIVAIDLFNGAGGTTSGLKKSGIDVQVAVEIDSVAVKTYKLN
                     NPEVSVIDME"
     gene            20381..21985
                     /locus_tag="VW348_001496"
     CDS             20381..21985
                     /locus_tag="VW348_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEU9746380.1"
                     /translation="MSEYWFSTNVDQIDEVDGKQCLIYSYYNVKASRNVEVLKGRSGT
                     KKGLDYWEPYAPQKQYEMERLPKNKYIGSSSTDRWDGIEKNVVFCDCKEYVSAFDLFF
                     YHYNFKKISTQRSKQDFIRLRSKPVADILKNNTSSYTRYKKEMVIDNVKVDDKVCEII
                     SEIMDESYTDIQILTHKLYSKGDDIKASKTIWMKKSGKEYSEAFAGTGEARIILLVND
                     IVNAQSNSLILIDEPEISLHPSAIYKFKEFLLQECLNKKHQIIITTHSTQLIKDFLRE
                     AVKLLVKNGEKVDVIENIDYQDAFFELGDVYHSRKMIYVEDRLAKYILEFVITHSGSE
                     NLKQNLVVRYIPGGANQIICNNILNSSYLDSDNHYFWFDGDQNTNVSESNNLMNYLEN
                     GVVISDKIPESDNKNLDDIIKLITGCPIKFNVSGNKGQKNNIELIAKQRSFIDYWAKY
                     VSYLPFPTPEFFLANLCNSVDREGYDFSKDGNGKEYFRKKTQVALGIENITSEDIFQE
                     QRRAVSKIQPESSMFQCIKEKLEALF"
     gene            22365..23168
                     /locus_tag="VW348_001497"
     CDS             22365..23168
                     /locus_tag="VW348_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEU9746381.1"
                     /translation="MQPTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(23284..24032)
                     /locus_tag="VW348_001498"
                     /pseudo
     CDS             complement(23284..24032)
                     /locus_tag="VW348_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         7360 a         4283 c         5265 g         7124 t
ORIGIN      
        1 tgataatttt tatattaaac ttgttccgta actgaaaagt gacatactat atgaatacaa
       61 aaatgatgtc acaattttct gttatggata atgaaatgct tgcttgcgtt gaaggtggag
      121 atattgattg gggaagaaaa attagttgtg cagcaggggt tgcatatggc gcaattgatg
      181 ggtgtgcaac aacggtttga catttctatt gggaccattt gctataggaa taggtgtaac
      241 tggtgctgca ggtggagcta tacttggagg tgtagcctat gtagcaacat gttggtggta
      301 attatggatt ttaaaagttt tattattggt ttagtagttg gtatatttgg tccttatatg
      361 gatgacttaa ttagaaaaat attttcaaaa tcttccaaaa aggatacgga tagtactctc
      421 taaaaaataa atttctcccc tgtatttgct agcttaattt acaggggagt ttctttaata
      481 ttgtttcgcc tgtcaaaatg atatgtgata gcaggatgaa aagtctacaa acaagttggt
      541 atcaatacaa cataaagagg aaagtatgtt tttcatgctt gcttttttta atttttacaa
      601 ttcaagaggt tttgatgacc atttatgatt tgagtgatcc aaggtcaaaa taagtgctat
      661 actagcagtg taaatgttct tgctcaacta agataaatcg cacatttagg aggaaatctt
      721 atgaagaaaa aaatactgat tattttcgtt ctgtatctga tcatgtccat ctttctttat
      781 ccgcttaggg agagtatttg gtataatcta ttttatacca tagcctatat gattgcggtt
      841 atgatctatt tttctttaat taaaaagaaa gaaaagaaat gaaagatttt cttgattaaa
      901 aagaatcata ttctttgtga gattgttcct ggggcagttg cctttgcttg tttctactta
      961 tctatttcta tttcgtcagt tttccaattt cttttagtgg ttattaactt agcttctatt
     1021 ttggtcactg tttacctcac tagggaaatg cggataaaag agtttgaaga cgatgatttg
     1081 gttagtccta gaaccaatca actcatgttt atcggcttga caggctttat gtctattatt
     1141 tgtttgtata gaggtatcac agcaggagaa tcttatcaac aactaatcgc ttatattggt
     1201 gctattcttt gcttgatcat catgcttcta ctcatttggg gtttgaagta ttataaaaag
     1261 taggggctaa tgaagttttt gcaatttagg aggtttcgat gacaattcaa gatttggatg
     1321 aaaaatttta aaaaacaatg atatactaaa cttgtcaaag ttgcaacggg tgctgctaca
     1381 ttatgttaaa aatcgctctt gattgataag ttggatttgt taggaaagga gtaaataatt
     1441 atggataaga aaaagatagt ttcgactata atatgtatag tatttcttgt agtgtcagta
     1501 gataattttt ttagagactt aaccccgtta ttgttcattt taaatattat tggcctaact
     1561 tgttttttag tgttaacata cactaacata aaagagatac tcttaaatat aagtaaatga
     1621 tgatttggtt agtcctagaa ccaatcaact tatgtttatc ggcttggcag attttatgtt
     1681 tgtcatttgt ttgtatagag gtatttcaga aacagaattc tatcaacaac taatcgctta
     1741 tataggtgta ttctctgctt gtttatcacg cttctgctca tgtggggctt gaagtattat
     1801 aaaaagtagc tttctatcct tttctgacag gatatttgag tagaaggctc tattaaattg
     1861 ttagtgaaat aaatgaatgg aggtatttaa tatgaaatac agattatttt ttgttatttt
     1921 cttgagtagt gtgttggata ttcttttagg gacattttta caaatctcta tcgtatctat
     1981 tgggtggctt gttctttaca gtggtttgtt tgaagcagga gttttccttc ttgctaataa
     2041 aggggtggcg gtaaaaatca aggaagtaga tattcgaaat cgctttaaat ttatttttgg
     2101 aaaaacctta tggtttcaaa ttcttttgct catctttttg ataatcaaac tttatcttgg
     2161 tttggatgcg aggttgattt tattctatgg acatattttc attgtcttta atgccttaat
     2221 gtatctatta tctagtagtc aggttagcct taaaaaaaac aaactgtctt cttaatctta
     2281 cagcagtaga gcctgacaag gtgaggttat agtagggagg atttctatga aaaagtatca
     2341 acttctattc aaaataagtg cagtcttctc ttacttattt ttcgtatttg gtctttctca
     2401 gctgacgctt atcgtccaaa actattggca attttcttct cagataggca atttattctg
     2461 gattcaaaat atcttgagtt tactttttat tggagtcatg attgtggttc ttgttaagac
     2521 aggccatggt tatctcttcc gcattccaag aaaaaaatgg ctttggtatt cgattttgac
     2581 agtattagtg gtagtgttcc agatctcttt taacgttcag acagctaaac atgttcagtc
     2641 aactgcggaa ggttgggctg tattgattgg ttatagtggg actaactttg cagagctagg
     2701 tatttatata gccctgttct ttctggttcc actgatggaa gaattgattt atagaggatt
     2761 actgcaacat gctttcttta agcattcgcg atttggtctt gatttgcttc ttccttctat
     2821 tttatttgct ctccctcatt tttcaagcct gcctagtctg ttagatatct tcgtctttgc
     2881 aacagttgga atcatctttg ctggtttgac ccgctatacc aagagcattt atccatccta
     2941 tgcggtgcat gtgatcaata atattgtagc gaccttcccg tttttgctca cttttctaca
     3001 tagggtcttg gggtaaaaaa acaaaaggct tgcttttcag ccatagagga ggtcatcatg
     3061 tataaacact tatttttcct agattccaaa actttagatc ggttgacacc ctatattcta
     3121 gtcttggctt ctgacaccat tgcttttaat gtttttgtgc taacctttgt atctgcggtg
     3181 gtttttaatt tcctaaattc catgctagct ttaatggcta tattcatagg ggctggctat
     3241 gtggtcggat tttggttact aatactcaat gaaaatcaaa gagcaaacta ggaaactagc
     3301 cgcaggctgt acttgagtac ggcaaggcga cgttgacgtg gtttgaattt gattttcgaa
     3361 gagtataaaa tggtttgttt tggaaaggct agaactaaag aatgacgtgt aggaagtctg
     3421 tttgttgagg aggataattt tatggagttt tttgataaat ttcatgcctt gtgttttgga
     3481 tttttagtac taataattgt cattacagtt ccttatacga ttaaccatgg gggttttttt
     3541 caaaatgaat ctgcattgat tcttgtaagt cttcttgtaa cctcgctgag tgttgcttat
     3601 gctagaaagt ttgaaatgat ttcttttggg atgttaagca agaaacaact tttgcttttc
     3661 attgcaatct ttcttctaag tgtacttgag acgctggttt atattcattt cttcgctgtt
     3721 tcttctggct caggggtcca acacttggcg gaagtcagca gaggaatttc cctgtctttg
     3781 attttgacta cctcagtttt tggccccatc caggaggaac tcattttcag aggacttctt
     3841 caaggtgcgg tttttgacaa ttcttggtta gggcttgtgc taacttcctc tctcttttct
     3901 ttcatgcatg gaccttctaa tgtcccttcg tttatttttt atctacttgg gggtttgttg
     3961 ctgggctttg cttataaaaa gagtcaaaac ctatgggttt ctactctagt ccatatgctt
     4021 tacaacagtt ggccactctt atattattta taaaaattat gaaaaggtaa gcagaagacg
     4081 gtgcttacct ttttcaagct ataatgatac ccaagccaat ccagaggctt ttctttgaga
     4141 atcgggttag agtggttgac gaataggcca aaaactagta gaatagtaag gaaactttat
     4201 acggaggaaa gaaatggatt tgggtgataa tgagctaaca ctgactccca tacctgggaa
     4261 aagtggcaag gcttatatgg gtagctatcc tgatgggaag cgcatctttg taaaaatgaa
     4321 cacctctcca atcctacctg gtctagctag agaacaaatt gctccacaat tattatggag
     4381 tcgtcgtttg gcagatgggc gtgatatgtg tgctcaagaa tggttgacag gcaagatatt
     4441 gaccccctat gatatgaatc gtaagcaaat cgtcaatatt ttaacccgtc ttcatcgctc
     4501 acgtccgttg atgacacaat tgagtcgttt gggctatgcc atggaaacac ctgtagattt
     4561 actacagtct tggcaggaaa cggctccaga tgctttgcgt aaaaatcatt ttatcagtga
     4621 agtgatggct gatttacgtc agactattcc aggatttaga gaggaccatg cgaccattgt
     4681 ccatggagat gtacgacata gtaattggat tgagacagat agtggcttga tttatttagt
     4741 agattgggat tcggttcgct tgaccgatcg catgtttgat gtggcccata tgctctgcca
     4801 ttatatttca gaacatcagt ggaaggaatg gttgacctac tacggttaca agtacaatca
     4861 aacggtatta agtaaattgt attggtatgg tcaattgtct tatttgagtc agatttccaa
     4921 gtattatatg aaccaagatt tagaaaatgt caatcgggag attcatggtt tgcgtcattt
     4981 ccgagacaag tatggaaaga gaagatgaga gttagaaatc gtaaaggggc aacagaatta
     5041 ctagaggcaa atccccagta tgtggtcctc aatcccttgg aagccaaggc aaaatggcgg
     5101 gacttgtttg gcaatgataa tcccattcat gtggaagttg gaagtggaaa gggtgccttt
     5161 gtttcaggta tggccaagca agaccctgac atcaactata tcgggattga tattcaaaag
     5221 tctgttttga gctacgcttt ggacaaggtg cttgaagttg gagtgcctaa catcaagctc
     5281 ttgtgggtag atggttctga cttaactgac tactttgaag acggtgagat tgatcgcttg
     5341 tatctgaact tttcagatcc atggccgaaa aaacgccatg aaaagcgtcg tttgacctac
     5401 aagaccttct tggatacctt caaacgtatc ttgcctgaaa atggagaaat tcatttcaag
     5461 acggataacc gtggcttgtt tgagtacagt ttagtgagct tttctcaata tggcatgaaa
     5521 ctcaatggtg tctggttaga tttgcatgcc agtgattttg aaggcaatgt catgacagaa
     5581 tacgagcaaa aattctcaaa caaggggcaa gttatctacc gagttgaggc agaattttaa
     5641 gagatagcct aaaattaggc tgtacaagtg cttttgcttt acataagttg gcaaacgtgc
     5701 tatactgata gtaagaatat gaaaagtgag gcggggaaat atcttcgcct cttgcttatg
     5761 aggaggtgga cgcaatcgca acaatcgtag aattagtcag agaagttgta gaacctgtca
     5821 tagaagctcc ttttgaactc gtggatatcg agtatggaaa gattggcagt gacatgattc
     5881 tcagtatttt tgtagataaa cccgaaggaa ttaccttgaa cgacacggca gacttgacag
     5941 aaattatcag tcctgtccta gacaccatca agccagatcc cttcccagaa caatatttcc
     6001 tagaaattac cagtccaggt ttggaacgcc ctttgaaaac caaggatgcc gtcgctggag
     6061 cggttggaaa atacatccat gtcgggctct accaagccat cgataagcaa aaggtctttg
     6121 aaggaacctt gttggccttc gaagaggacg agttgactat ggaatatatg ggcaagacgc
     6181 gtaagaaaac cgtccaaatt ccatacagtt tagtatcaaa agcacgttta gcagttaaat
     6241 tatagaaaaa gaaaggatag cttttgagga ttcaaaagtg aagaaaacat gagtaaagaa
     6301 atgctagagg ccttccgcat tttggaagaa gacaagggaa tcaaaaaaga agatatcatc
     6361 gacgcagtag tagagtcgct tcgttccgct tatcgcagac gctatggtca gtcagacagc
     6421 gtagctattg acttcaacga aaaaacaggt gactttacag tttatactgt ccgtgaagtt
     6481 gttgatgaag tatttgatag ccgtttggaa atcagcttga aagatgctct tgccattaat
     6541 tcagcttatg aacttggaga caaaatcaag tttgaagaag caccagctga gtttggtcgt
     6601 gtagcagccc aatctgccaa acaaaccatc atggaaaaaa tgcgcaagca aacacgtgcc
     6661 atcacttaca atacttacaa agaacatgag caagaaatca tgtctggtac agtagaacgc
     6721 tttgacaacc gctttatcta tgtcaacctt ggtagcatcg aagcccaatt gtcaaaacaa
     6781 gaccaaattc ctggagaagt ttttgcttct catgatcgta tcgaagttta tgtttacaag
     6841 gttgaagaca accctcgtgg tgtgaacgtc tttgttagcc gtagccatcc agaaatgatc
     6901 aaacgtttga tggagcaaga aattccagaa gtttatgatg gaactgttga aatcatgagc
     6961 gtggctcgtg aagcaggtga ccgtacgaag gttgctgttc gtagccacaa tccaaacgtg
     7021 gatgctatcg gtacaatcgt tggacgtggt ggtgctaata tcaagaagat tactagcaaa
     7081 ttccacccag ctcgttacga tgctaaaaat gaccgcatgg taccaatcga agaaaatatc
     7141 gatgttatcg agtgggtagc agatccagct gaatttatct acaatgccat cgctcctgct
     7201 gaggttgacc aagttatctt tgatgaaaac gacagcaaac gtgccttggt ggttgttcca
     7261 gataacaagc tttctcttgc cattggtcgt cgtggacaaa acgtgcgctt ggcggctcac
     7321 ttgactggtt accgtatcga tatcaagtct gctagcgaat ttgaagccat ggaagacgct
     7381 gcttcagtag agttggaagt agaaaacgat actgtagaag aataaaagct gctagaggag
     7441 ggaaagatga aaacaagaaa aatccctttg cgcaagtctg ttgtgtctaa cgaagtgatt
     7501 gataagcgtg atttgctccg cattgtcaag aacaaggaag gacaagtctt tattgatcct
     7561 acgggcaagg ccaatggccg cggcgcttat atcaaactag acaatgcaga agccctagag
     7621 gcgaaaaaga agaaggtctt taaccgcagc tttagcatgg aagtggaaga aagcttttat
     7681 gacgagttga tcgcttatgt ggatcacaaa gtgaaaagaa gagagttggg acttgaataa
     7741 gcaaaagata agtaatctct tggggcttgc tcagcgagca gggcgcatca tatcgggtga
     7801 agaattggtg gtcaaggcca ttcaagacgg caaggccaag ttggtctttc tagctcatga
     7861 tgctggaccc aatctgacca agaagattca agataaaagt cattattatc aagtagaaat
     7921 tgtaaccgtg ttttcaacac tggaattaag catagcagtc gggaaatcga gaaaggtttt
     7981 ggctgtaaca gatgctggat ttacaaagaa aatgaggtct cttatggaat agaagaggag
     8041 gacatgattt gtctaagaaa agattgtacg aaatcgcaaa agaacttgga aaagaaagta
     8101 aagaagttgt agcgcgtgca aaagagttgg gcttggatgt gaaaagccac tcatcaagtg
     8161 tggaagaagc tgtcgctgca aaaattgctg ccagctttaa gcctgcagct gctccgaaag
     8221 tagaagcaaa acctgcagca ccaaaagtaa gtgcagaaaa gaaaaccgaa aaatctgagc
     8281 cagctaaacc agctgtagct aaggaagagg caaaaccggc tgagccagtt gctccgaaaa
     8341 cagaaaaagt agcagcgaaa ccgcaaagcc gtaatttcaa ggctgagcgt gaagcccgtg
     8401 ctaaagagca ggcagaacga cgcaagcaaa ataagggcaa taaccgtgac caacaacaaa
     8461 acggaaaccg tcagaaaaac gatggccgta atggtggaaa acaaggtcaa agcaaccgcg
     8521 acaatcgtcg ctttaatgac caagctaaga agcagcaagg tcagcaaaaa cgtagaaatg
     8581 agcgccgtca gcaagaggac aaacgttcaa atcaagcggc tccacgtatt gactttaaag
     8641 cccgtgcagc agccctaaaa gcagagcaaa atgcagagta cgctcgttca agtgaggaac
     8701 gcttcaagca gtatcaggct gctaaagaag ccttggctca agctaacaaa cgcaaggaac
     8761 cagaggaaat ctttgaagaa gcggctaagt tagctgaaca agcacagcaa gttcaagcag
     8821 tggttgaagt cgtccctgag aaaaaagaac ctgcagtgga tacacgtcgt aaaaaacaag
     8881 ctcgaccaga caaaaatcgt gacgattatg atcatgaaga agatggtcct agaaaacaac
     8941 aaaagaatcg aagtagtcaa aatcaagtga gaaatcaaaa gaatagtaac tggaataaca
     9001 acaaaaagaa caaaaaaggc aataacaaga acaaccgtaa tcagactcca aaacctgtta
     9061 cggagcgtaa attccatgaa ttgccaacag aatttgaata tacagatggt atgaccgttg
     9121 cggaaatcgc aaaacgtatc aaacgtgaac cagctgaaat tgttaagaaa cttttcatga
     9181 tgggtgtcat ggccacacaa aaccaatcct tggatgggga aacaattgaa ctcctcatgg
     9241 tggattacgg tatcgaagcc aaacaaaagg ttgaagtgga taatgctgac atcgaacgtt
     9301 tctttgtcga agatggttat ctcaatgaag atgaattggt tgagcgtcca ccagttgtta
     9361 ctatcatggg acacgttgac cacggtaaaa caaccctttt ggatactctt cgtaactcac
     9421 gtgttgcgac aggtgaagca ggtggtatta ctcagcatat cggtgcctac caaatcgtgg
     9481 aaaatggtaa gaagattacc ttccttgata caccaggaca cgcggccttt acatcaatgc
     9541 gtgcgcgtgg tgcttctgtt accgatatta cgatcttggt cgtagcggca gatgacgggg
     9601 ttatgcctca gactatcgaa gccattaacc actcaaaagc ggccaacgtt ccaatcatcg
     9661 tagccattaa caagattgat aaaccaggtg ctaacccaga acgcgttatc ggtgaattgg
     9721 cagagcatgg agttatgtca actgcttggg gtggagattc tgaatttgtt gaaatctcag
     9781 ctaaattcaa ccaaaatatc gaagaattgt tggaaacagt ccttcttgta gctgaaatcc
     9841 aagaactcaa ggcagaccca acagtgcgtg caatcggtac ggttatcgaa gcgcgcttgg
     9901 ataaaggaaa aggtgcggtc gcaacccttc ttgtacaaca aggtaccttg aatgttcaag
     9961 acccaatcgt tgtcggaaat accttcggtc gtgtccgtgc tatgaccaac gaccttggtc
    10021 gtcgtgttaa agttgctgga ccatcaacac cagtctctat cacaggtttg aacgaagcac
    10081 cgatggcggg tgaccacttt gccgtttacg aggatgaaaa atctgcgcgt gcagcaggtg
    10141 aagagcgtgc caaacgtgcc ctcatgaaac aacgtcaagc tacccaacgt gttagccttg
    10201 aaaacctctt tgataccctt aaagctgggg aactcaaatc tgttaatgtt atcatcaagg
    10261 ctgatgtaca aggttctgtt gaagcccttt ctgcctcact tcaaaagatt gacgtggaag
    10321 gtgtcaaagt gactatcgtc cactcagcgg tcggtgctat caacgaatca gacgtgaccc
    10381 ttgccgaagc ttcaaatgcc tttatcgttg gtttcaacgt acgccctaca ccacaagctc
    10441 gtcaacaagc agaagctgac gatgtggaaa tccgtcttca cagcattatc tacaaggtta
    10501 tcgaagagat ggaagaagct atgaaaggga tgcttgatcc agaatttgaa gaaaaagtta
    10561 ttggtgaagc agttatccgt gaaaccttca aggtgtctaa agtgggaact atcggtggat
    10621 ttatggttat caacggtaag gttgcccgtg actctaaagt ccgtgttatc cgtgatggtg
    10681 tcgttatcta tgatggtgaa ctcgcaagct tgaaacacta taaagacgac gttaaggaag
    10741 ttacaaacgg ccgtgaaggt ggattgatga tcgacggcta caatgatatt aagatggatg
    10801 atgtgattga ggcgtatgtc atggaagaaa tcaagagata agattttttg ctcctttctt
    10861 aggtggtgag ggacgcaagc aaaccgatgg tttcattgct tatttttgag cctagggtct
    10921 caaaaatccc ctgtgatggg actgataaat cagttccatc actttcacca cggcgaaaga
    10981 agcagatgac ttcaaattga acttcgtttc aatttaaact gaaaatcaag aagtttaaaa
    11041 tagctaggtc tgctggccta gcttttggtt caaagtagag aaaggaatat catggcaaat
    11101 catttccgta cagatcgtgt gggcatggaa atcaagcgtg aagtcaatga gattttgcaa
    11161 aagaaagtcc gtgatccacg tgtccaaggt gtgaccatca cagatgttca gatgctgggt
    11221 gacttgtctg ttgccaaggt ttattacacc attttgagta accttgcttc ggataaccaa
    11281 aaagcccaaa tcgggcttga aaaagcaact ggtaccatca aacgtgaact tggtcgcaat
    11341 ttgaaattgt acaaaatccc agatttgacc ttcgtcaaag acgagtccat cgagtatgga
    11401 aacaagattg acgagatgct acgcaatctg gataagaact aaagaagagg ggttgcccct
    11461 cttttttggt ggaggaaaat aggttgaatt tgaaatggaa aaatattctt ttaaaatata
    11521 ttgaaactag aatagtacgc ctctacttct aaaacattgt tagaaatcga tttgactgtc
    11581 ctgatcgatt tgtcctgttc gtgtttcatt ttactataaa aaaaggggtt ctgtattttt
    11641 taatgttatc taattagaaa atgctttttt tgtaggaaat ataatatgat aaggtgtaaa
    11701 aaagaaataa ggagtttgta tatggctgaa caagacttag ctatgcaagt attacaacaa
    11761 gtggtaaaac taccagttgt taaggttgat cgttcgaaat ttttagtgga taagttttcc
    11821 aaagaattgg gtccacagga cattcctacc ttattggaac aaggtccaac gtctctctta
    11881 tctcaagaaa tcttagatcg agtggctaat gcctgtatta gggataatgt tttattagcg
    11941 agtgggactt ctgttttggc aggattacct ggagggcttg ctatggcaat taccattcca
    12001 gctgatgtgg ctcaatttta tgctttctct ctgaaattgg cccaagaatt aggttatatt
    12061 tatggttatg aggatctttg ggcttcacgc gatgagttga gtgaagatgc tcaaaatacc
    12121 ctcttgcttt atctaggcgt catgttgggg gtgaatggaa ctgctgcttt gctacgtgct
    12181 ggtggtataa caattgccaa acaggtaatg aaaacagtac ctaataaagc tttaactaag
    12241 acgctttggt atcctatttt gaaaaaagtc ttaagaatat ttggtgtgaa tcttaccaag
    12301 ggagggctgg ccaaaggaat ggggaaattt attcctatct tgggtggtat catttcaggt
    12361 ggtttaacct ttgcaactat gaaaccgatg ggtgaaagct tgcagaaaga attgtccaag
    12421 ctagttaact atagtgaagt tcaatatcaa gaagatgttg aaacaatccg aaaagaggct
    12481 gaaatcatcg aaggagagta atatgggact cataaaaact ctagctaaaa tttatggtaa
    12541 ttactttttg accgtgcaag gtgtaaaagt gatgaaaacg ataaagaaag ctgaccatgt
    12601 cgttgttggt ctgggcaaac tttttattgc agataagcta atggatacgg ctcggtggct
    12661 cattaagcca gaggagagag aatgaaattt ttttggtctt cttgctattc tttttatcaa
    12721 accgattatt gggattgtga aattcttttg gatgatcatt tcttttgcag ttcaattgct
    12781 gttttacaag atattggatt ggttctttaa acttatctag atggtaatcc aagtcgcaga
    12841 aaactagcag gaaccccact gctagttttt taatctctct ccatatggta taatataagc
    12901 agtaaaatca ttttatactc ttcgaaaatc tcttcaaacc acgtcagctt caccttgctg
    12961 taggtatggt tactgacttc gtcagttcta tctacaacct caaaacggtg ttttgagctg
    13021 acttcgtcag ttctatccac aacctcaaag cactgttttg agcagtctgc agctagcttc
    13081 ctagtttgct ctttgatttt cattgagtat tagaacatac aatggaggtc gtcatggaca
    13141 atatcatcga tgtgtcaatt cctgttgcag aagtggtgga caagcatcca gaagtcttgg
    13201 aaattctagt ggagttgggt tttaaacccc ttgccaatcc cttaatgcgc aatacagttg
    13261 gtcgcaaggt atcgctcaaa cagggttcta agctagcagg aactcctatg gacaagattg
    13321 tacgcacact ggaagcgaat ggctacgaag tgattggatt agactaatgg cagatgaacg
    13381 gattcatgtc ctacgggata ttttgttaga attgcacaat ggcgcctctc ctgagtcggt
    13441 tcaagagcgc tttgatgcga cctttgcggg tgtctcagcc atcgagattt cccttatgga
    13501 gcacgagctg atgaactcag actcaggtgt cacctttgaa gatgttatgg aactctgtga
    13561 tgtccatgcc aatcttttta aaaatgctat caaaggtgtc gaagtttcag atactgagca
    13621 tccaggtcac ccagttcgtg tcttcaaaga agaaaatctg gctctccgtg cggccttgat
    13681 tcgcattcgt agattgttag atacctatga gtatatggaa gacgaggaaa tgctggcgga
    13741 gatgcgtaag ggtttggtgc gtcagatggg acttgtgggt caatttgaca tccattacca
    13801 acgtaaggaa gaactcttct ttcctatcat ggagcgctat ggacacgatt cacctcccaa
    13861 agttatgtgg ggagtggatg atcagattag ggaactcttt caaacagctc taacgacagc
    13921 caagtcacta ccagaagtgt caattagcag tgtaaaggaa gcttttgaag cttttgcgac
    13981 agagtttgaa agtatgattt tcaaggaaga gtccatcctc ctcatgattc tccttgagtc
    14041 ttttactcag gatgactggc ttcagattgc ggaggagagc gatgcctatg gctatgccat
    14101 catccgtccg tcagagaaat gggtgccaga acgacagagc tttattgagg aaaagattgc
    14161 agaggagcct gtacagctag atacggcaga aggtcaagtt caacaagtca tagatacgcc
    14221 agaaggccat tttaccatta cctttacccc taaggaaaag gaagctgtgc tggaccgcca
    14281 tagtcaacag gcttttggta atggctatct ttcagtcgag caggccaatc tcatcctcaa
    14341 tcacctccct atggagatta cctttgtcaa taaagatgat attttccagt attacaatga
    14401 caatacgcca gctgatgaga tgattttcaa acggacgccg tctcaagtcg ggcgcaatgt
    14461 cgaactctgc catccgccta agtacttgga caaggtcaaa actatcatga aggggcttcg
    14521 tgagggaagc aaagacaagt atgaaatgtg gttcaagtct gagtcgcgag gtaagtttgt
    14581 ccacatcacc tatgctgcag tacacgatga agacggagaa ttccaaggag tgttggagta
    14641 tgttcaggat atccagccct accgtgagat tgatacggac tattttcgtg gattagaata
    14701 aggagaaaaa atgagttacg aacaagaatt tatgaaggaa tttgaagctt gggtcaatac
    14761 ccaaatcatg attaacgaca tggcgcacaa ggaaagtcaa aaagtttacg aagaagacca
    14821 ggacgagcgt gccaaagatg ccatgattcg ctacgagagt cgcttggatg cttatcagtt
    14881 cttgcttggt aagtttgaaa acttcaaagc aggcaaggga ttccatgatt tgccagaagg
    14941 cttgtttggt gagcgaaatt attaaacgag aaagattctt gatttttcac taaaatcttg
    15001 atagaatgtt tatgttaaat ccttgtcaga gcagggattt tttattgaaa ggattttatc
    15061 atgtcaaaga aactcaatcg taaaaaacaa ttacgaaatg gcctccgtcg cgcaggtgcc
    15121 ttttcaagta ctgtgactaa ggttgtagat gagacaaaaa aagtcgtgaa gcgtgcagaa
    15181 cagccagcaa gcgcagctgg taaggctgtt tctaaaaaag ttgaacaagc agtagaagct
    15241 accaaagagc aagctcaaaa agtagctaat tctgtagaag attttgcagc aaacttgggg
    15301 ggacttccac ttgatcgtgc caagactttc tatgatgaag gaatcaagtc tgcttcagat
    15361 ttcaaaaact ggactgaaaa agaactcctt gccttgaaag gaatcggccc agctaccatc
    15421 aagaaattga aagaaaatgg catcaagttc aagtaatttt tcttgagcct tgcatttccg
    15481 agaaaaactt gctacaatag agccattaga ggtgttttga atcccacatt ttacagaaag
    15541 tggcggcgct gagaagtcca caaatgtgtc aaaactggtt gctaatgact gaaaaaatga
    15601 aatatttctg tctttttatt ttaaagacta aagatgcggg cttggcccga aattgggtgg
    15661 taccgcggat aaacacattc gtccctgtca tgtagatggc agggcttttc ttttgtgtct
    15721 tagtcaaagg aggttgttat aaaacaatca tttaaaacta ataaactata ttatggtttt
    15781 cctgttttta ttttaggata tcaagatcag aattttagct ataacatcat gacctgtagt
    15841 tcctcttata gtctaggaga ttgggttgtg attggagtcg ttgcgagaga gaatgccgca
    15901 gagcagatca aacaatatca aaaatttact gtgaatattt ctgatgaaac ttctatgctt
    15961 gcgatggagc aggctggttt tatcagtcat caggagaaat tggaacgttt gggagtgcat
    16021 tatgaaattt ctgaacgaac tcagactcct attttagacg cctgtccact tgttttagat
    16081 tatcgggtag ataggattgt tgaggaatac ggtatttgcc acatctttgc caagattctt
    16141 gagcgacttg ttgccccaga actcctggat gaaaagggac attttaaaaa tcaactgttt
    16201 gcccaaccta tttcatggga gatggatatc agcgcgttta ttgctatctg gacaagcgtg
    16261 tagatatgaa gggcagtttc atcaaaaaag cgaggaagaa ggatggcaag aactgagctg
    16321 ccagataaaa tcgaaacaga acgtctcgtt ttacgagtcc gtactgtggc ggatgctgag
    16381 gatatctttg actatgctag tttgccagag gtcgcctatc cagcaggttt tcctccagtc
    16441 aagaccttgg aagatgagat ttattatctg gagcacattt ttccggagcg taatcaaaag
    16501 gaaaatctcc cagcaggcta cgggattgtc gtcaaaggaa cggataagat cgttggctct
    16561 gtcgatttca accatcgcca tgaagatgat gtgctggaaa tcggctatac cttacaccca
    16621 gactattggg ggcgaggtta tgtgccagaa gctgcgcgtg ccttgattga cttagccttt
    16681 aaagatttgg gtcttcacaa gattgaacta acttgctttg gatataacct tcaaagtaaa
    16741 cgagtcgcgg aaaagcttga ctttaccctc gaagctcgca taagagaccg caaagatgct
    16801 caaggcaact gctgtgatga tttaagatat gccttgctga agagtgaatg ggaggtgatt
    16861 tgatgcatct tttcatcatt ggtgctccag catcaggaaa aatgaccatt ggtcaagaat
    16921 tatctcgact gacggatgct accctatttt ataaccatca agccatcgat tttgcactag
    16981 aaatctatca ggactataca gaggaaatgt gggaatttgt tcgtggaatc actttttcat
    17041 tccttggagc gagtgcaaga aatcagcgat cagtaatttt aacagatgta attgattttt
    17101 caaatcagta tcatctgata tatttaaagc aaattcagag tttgttggat gattatcatc
    17161 aagagattct ttttgttgag ttggaaacaa gtcttgaaga gtgcatacgt cgaaatcgaa
    17221 cggagaatcg attaaagtac aaacccttaa aacgacatat tgaggtatct gaaagagaaa
    17281 ttatagagac cgctgaaata cttcaattaa attcccaata tcaaccgaat gagttgcacc
    17341 actactttaa aataaataat acgaatttgt ctgcagaaga agctgctaag caaattcaaa
    17401 ataaaataaa caaaatagag aaaggacaca cacatgtcta aagaactttc atctaaatac
    17461 aatccagccg aggttgaggc tggtcgttac caaaaatggc ttgatgctga tgttttcaag
    17521 ccttcaggcg atcaaaaggc taagccttat tcaatcgtta ttccaccacc aaacgttaca
    17581 ggtaaacttc accttggtca cgcttgggat acaactttgc aagatattat catccgtcaa
    17641 aaacgcatgc aaggttttga tacgctttgg cttccaggaa tggaccacgc tggtattgcg
    17701 actcaggcta aggttgagga gcgcttgcgt ggtgagggca tttcccgcta tgaccttggt
    17761 cgtgagtctt tcttgacgaa agtctgggaa tggaaagacg aatatgccac taccatcaag
    17821 gaacaatggg gcaagatggg gctctctgta gactattctc gtgagcgttt cactcttgac
    17881 gaaggtttgt caaaagctgt tcgtaaggtc tttgtggacc tttacaagaa aggctggatc
    17941 taccgtggtg agtttatcat caactgggac ccagcagctc gcacagccct ttctgatatt
    18001 gaggtgattc acaaggatgt ggaaggtgcc ttctaccaca tgaattacat gctggaagat
    18061 ggttcacgcg cccttgaagt tgctacaact cgtcctgaga ctatgtttgg ggacgttgcg
    18121 gttgcggtta atccagaaga cccgcgctac aaggacttga ttggtaaaaa cgtcatcctt
    18181 ccaatcgcta ataaactcat cccaatcgtt ggagatgagc acgcagatcc tgagtttggt
    18241 actggtgtcg tgaaaatcac acctgcccac gatccaaatg acttcttggt tggccaacgt
    18301 cataacttgc cacaagtcaa cgtcatgaac gacgacggaa ctatgaatga gcttgccttt
    18361 gaattttcag gcatggatcg ttttgaagct cgtaaggcag tcattgctaa gttggaagaa
    18421 atcggtgccc ttgtcaaaat cgaaaaacgt gtccacagtg ttggtcactc agaacgtaca
    18481 ggtgtcgtag ttgagccacg cttgtctact caatggttcg tcaagatgga ccaattggct
    18541 aagaacgcca ttgccaacca agacacagag gacaaggtcg aattctaccc acctcgtttc
    18601 aacgatacct tccttcaatg gatggaaaat gtccacgact gggttatctc tcgtcagctt
    18661 tggtggggtc accaaatccc tgcctggtac aatgctgatg gtgaaatgta tgtcggcgaa
    18721 gaagctccag aaggtgacgg atggactcag gacgaagacg tcttggatac ttggttcagt
    18781 tctgccctct ggccattttc aaccatgggc tggcctgaag tcgactcaga agactttaaa
    18841 cgttatttcc caacttcaac cttggtaaca ggttacgaca tcatcttctt ctgggtgtct
    18901 cgtatgatct tccagtcatt ggaattcaca ggccgtcaac cattccaaaa cgtccttatc
    18961 cacggtctca ttcgtgacga gcaaggacgc aagatgtcta agtctctcgg taacgggatt
    19021 gacccaatgg atgttatcga gaaatacggt gccgatgccc ttcgatggtt cctttcaaac
    19081 ggttctgcgc caggacaaga cgtgcgtttc tcttatgaga aaatggatgc ttcatggaac
    19141 tttattaaca agatttggaa catttctcgc tatatcctca tgaacaatgg aggtttgacg
    19201 ctggatgtgg cgcatgacaa tgtcacaaaa gttgcaacag gtgaggctgg taatgtgacg
    19261 gaccgctgga ttctccacaa tctcaacgaa accattgcaa aagttactga aaactttgat
    19321 aagttcgagt ttggtgtggc tggtcatatc ctttacaact tcatttggga agaatttgcc
    19381 aactggtatg ttgagttgac caaggaagtt ctttacagcg acaatgaaga cgataaggta
    19441 attactcgat ctgttctcct ctatacgctg gataaaatcc ttcgtctcct tcactcaata
    19501 atgccgttcg tgacagaaga aatctttggt cagtacgctg aaggctctat cgtgacagca
    19561 gcatacccaa ctgtcaaccc agcctttgag gaccttgctg cccacactgg tgtggaaagt
    19621 ctcaaagact tgatccgtgc cgttcgtaat gcgcgtgcgg aagtaaatgt agcaccaagc
    19681 aaacctatca ccatccttgt taagacaagc gatagcgact tggaagcctt ctttaacagc
    19741 aatgtcaact atatcaaacg ctttacaaat ccagaacact tggaaatcgc atcaaccatc
    19801 cctgcacctg aactggctat gtcaagcgtt attacaggag ccgaaatctt cttgccactg
    19861 gtagacctct tgaatgtcga agaagaattg gcacgtctgg aaaaagaact tgccaaatgg
    19921 cagaaagaac tcgacatggt tggcaaaaaa ctcagcaacg aacgcttcgt cgccaacgct
    19981 aaaccagaag ttgtccaaaa agaaaaagac aaacaagccg actaccaagc caagtatgat
    20041 gcgaccgtag cacgtattga tgagatgaag aagttggtga aatgatgtta aaaacctaac
    20101 cctatcgggt tgggttttac atttgataat gttataataa aaaggagaaa ctttaggaga
    20161 atactatggg gaaaattgtt gctattgatt tatttaacgg tgcaggtggc actacaagtg
    20221 gccttaaaaa atcaggcata gatgttcaag ttgctgttga aattgattcc gtagctgtta
    20281 aaacttataa gttaaataat cctgaggtgt ctgtaataga tatggagtaa ataaaacttc
    20341 aattttacaa gctttatatg gttctccagc caataaaagt gtgtctgaat attggtttag
    20401 tacaaatgtt gatcaaatag atgaagtgga tgggaaacaa tgtttaatct attcatatta
    20461 taacgttaaa gcttctagaa atgtagaagt tcttaaaggc cgttctggaa caaaaaaagg
    20521 attagattat tgggaaccat atgctcctca aaaacaatat gagatggaaa gattacccaa
    20581 aaataaatat attggaagtt cttcgacaga cagatgggat ggcattgaaa aaaatgttgt
    20641 cttttgtgat tgtaaagaat atgtttctgc ttttgattta tttttctatc actataattt
    20701 taaaaaaatt tctactcaac gtagtaaaca agattttata agattacgat ctaaaccagt
    20761 tgctgatatt ttaaagaata atacaagtag ttatacgcgt tataaaaagg aaatggttat
    20821 agataatgtt aaagttgatg ataaagtttg tgaaattatt agtgaaataa tggatgaatc
    20881 ttatacagac attcaaattt taacacataa gttgtattca aaaggtgatg atataaaagc
    20941 ttccaaaact atttggatga aaaaatctgg aaaagaatat tccgaggctt ttgcaggaac
    21001 aggtgaggct agaattattt tgttagtaaa tgatatagta aatgcgcaat caaattcatt
    21061 aatattaata gatgaacctg aaatctcact tcatccgagt gcaatctata aatttaaaga
    21121 gtttttactt caagagtgtt taaataaaaa acatcaaatt attatcacta cacattctac
    21181 acaacttata aaagattttc ttagagaagc cgtgaaactt ttagtgaaaa acggagaaaa
    21241 ggtagatgtt attgaaaata ttgattatca ggatgcattt tttgaattag gtgatgtgta
    21301 tcattctagg aagatgattt atgttgaaga tagactagct aaatatattc tagagtttgt
    21361 tatcactcat tcaggtagtg agaatcttaa acagaattta gtagtgagat atattcctgg
    21421 tggagcaaat caaataattt gtaataatat tttaaactca tcgtatttag attccgataa
    21481 ccattatttt tggtttgatg gagatcaaaa cactaatgtt agtgaatcaa ataatttaat
    21541 gaactatctt gaaaatggtg ttgttatatc agataaaatt cctgaatcag ataataaaaa
    21601 tcttgatgat attataaaat tgataacggg atgtccaatt aaatttaatg tttcaggtaa
    21661 taaagggcaa aaaaataata ttgaattaat tgcgaaacaa agaagcttta tagattattg
    21721 ggctaaatac gtttcttatc ttcctttccc aaccccagag ttttttttag ctaatttgtg
    21781 taacagcgta gatagggaag gttatgattt ttctaaagat ggcaacggaa aagaatattt
    21841 tagaaaaaaa actcaagtag cgttaggaat agagaatata acttctgaag atattttcca
    21901 ggagcaaaga agagctgttt caaaaataca gccagaatca tcaatgtttc agtgtattaa
    21961 agaaaaatta gaggcattgt tctaattcct tagattaggt actacataac aaatttttta
    22021 aattcaaacc cgcaccaaaa acaacattgc aactttcttc tcaggtaatg tgttgggatt
    22081 tgaacagacc aacgagttca tagaggtgta tgccaatgag tttgataagt atgcgcgtca
    22141 gacttattag ttcatttatc cagatatatc tcgataatca tattatttag tcaaagaaca
    22201 tcccatatga gggcatgaaa tgctaagttt agcttgctca ctattaagat gaagtatata
    22261 tatttcatag aacttattgt gaaggatttt tataattttc gccaattcca tacccatttc
    22321 accatttacc gatgacacag aaaaacaatt gaaaggatat ttctatgcaa ccaacttaca
    22381 acattgacaa tccaaacttg tcttatgaag cgaagcgtga tttatggcgg ataggttttg
    22441 gtctgcagaa agttgacaat ctagtgccat cagcgtatat ggaatctttg gctgagaaac
    22501 agtcccgggg agaactgact tatgagcagg tttatgagga tgcaacggct tatcaccata
    22561 ctattgatgc aagtacggaa gaggcagact tggtttctct acgtattgta gaactattgt
    22621 ctcgaagagg ctttagcttt agtcctgcga ccttacttgc tattcataag gagttgtttc
    22681 aagatatatt tgaaccctct attccggtgg ggcaatttcg tcagaccaat atcacaaaga
    22741 atgaacctgt tttgaatggt gaaagtgttg tgtactctga ttactccatg attcaaatga
    22801 ccttagatta tgattttaat caggaaaaac aagttgcata tgcgacacta actcaggcgg
    22861 atgtggttaa acaaatccag cattttattt caggaatctg gcagattcat ccatttcgcg
    22921 aaggaaacac tcggacagta acggtctttt tgattcagta tcttcgtgag tttggttttg
    22981 atattgataa tacaccattt cagcaacatt ccaaatattt tcgtgatgcc ttggtattag
    23041 ataatgcaaa gattttacag cgacgtcctg agtttttaac agcttttttt gaaaatctct
    23101 tgctcggtgg tcaaaatgat ttgtcttcag aaaaaatgta tctagattta gaccttgatt
    23161 tttcataatc caaatactga gtaaacattg aattttaggc aaaaatgaag taaatattct
    23221 cacaagaaaa cgtatatcat caaagtttta ggtgtactga ccccaaacag ttagacaatt
    23281 aatttatccg aaggatttag ttctgtattg cacaggacta agtcctttta gttttacctt
    23341 aattcgttta ttgttgtagt aatcaatata gtctacaata gcttgttcca attgcttaag
    23401 cgactgaaac gacttctcat aaccgtaaaa catttccgat ttcagaatcc caaagaaaga
    23461 ttccatcata ccgttgtctt ggctgtttcc cttgcgtgac atggatgctt gaactccctt
    23521 actctctagg aaccgatgat aagaatcgtg tcggtattgc cagccttggt cactatggag
    23581 aatcgtattc tcatagtgct tctctgtgaa tgcctgttcc aacattgttt gtacttgttc
    23641 taagttgggt gaagttgaaa gattataggc gataatttcg ctattaaagc catctaaaac
    23701 tggtgataag taaagctttt gagtacttgc tggaatggca aattctgtca catctgtgta
    23761 gcactgttcc attgttttag agccttcaaa ttggccttga atgagattct ctgccttctt
    23821 gccaacgtct cctttatgag aagaatattt tcgtttctgt cgcattttag cttgtaaatt
    23881 gagtacttca tcaagtgttg aactctttta tgatttacca gataaccacg atttcttagt
    23941 tctaaataaa tccgacgata accataattt cccttgtgtt cgataaagat ggattgaatt
    24001 tcagctttaa gctcttggtc cttatctgtt tt
//
LOCUS       DAVKMJ010000034        23241 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000034 DAVKMJ010000000
VERSION     DAVKMJ010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23241
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.034"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            284..1765
                     /locus_tag="VW348_001499"
     CDS             284..1765
                     /locus_tag="VW348_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9746382.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            2127..3128
                     /locus_tag="VW348_001500"
     CDS             2127..3128
                     /locus_tag="VW348_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9746383.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILEKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3279..4196
                     /locus_tag="VW348_001501"
     CDS             3279..4196
                     /locus_tag="VW348_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9746384.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4207..5097
                     /locus_tag="VW348_001502"
     CDS             4207..5097
                     /locus_tag="VW348_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9746385.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            5126..6742
                     /locus_tag="VW348_001503"
     CDS             5126..6742
                     /locus_tag="VW348_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEU9746386.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     PDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6752..8071
                     /locus_tag="VW348_001504"
     CDS             6752..8071
                     /locus_tag="VW348_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEU9746387.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(8282..8354)
                     /locus_tag="VW348_001505"
     tRNA            complement(8282..8354)
                     /locus_tag="VW348_001505"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8319..8321),aa:Lys,seq:ctt)
     gene            complement(8619..9890)
                     /locus_tag="VW348_001506"
     CDS             complement(8619..9890)
                     /locus_tag="VW348_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEU9746388.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
     gene            10160..10360
                     /locus_tag="VW348_001507"
     CDS             10160..10360
                     /locus_tag="VW348_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746389.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQ"
     gene            10564..10743
                     /locus_tag="VW348_001508"
     CDS             10564..10743
                     /locus_tag="VW348_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746390.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            10880..11059
                     /locus_tag="VW348_001509"
     CDS             10880..11059
                     /locus_tag="VW348_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEU9746391.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERLITIPHGE
                     LNKYTERGIRKQAGL"
     gene            11096..11548
                     /locus_tag="VW348_001510"
     CDS             11096..11548
                     /locus_tag="VW348_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEU9746392.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11839..12309
                     /locus_tag="VW348_001511"
     CDS             11839..12309
                     /locus_tag="VW348_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEU9746393.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVLSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            12328..13416
                     /locus_tag="VW348_001512"
     CDS             12328..13416
                     /locus_tag="VW348_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEU9746394.1"
                     /translation="MKKIGTYLVYVLAFVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQFKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            13397..13555
                     /locus_tag="VW348_001513"
     CDS             13397..13555
                     /locus_tag="VW348_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7,8-dihydro-8-oxoguanine-triphosphatase"
                     /protein_id="HEU9746395.1"
                     /translation="MELEISDFPGCKIALFCGDKLLTILRDDKASIPWANMWELPGGG
                     KSVRENLI"
     gene            13665..14699
                     /locus_tag="VW348_001514"
     CDS             13665..14699
                     /locus_tag="VW348_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU9746396.1"
                     /translation="MKKSDVLDLIKYHYEGRETEFRNQSIAIARNFNKHGDTQIAQYI
                     MGLMSQSDRFMPQIENPSEYLTPAKLDIGPLPLPLSIMNDLKGIINAVNHHIGINKFL
                     FVGSPGTGKTESVKQVARLIGKELLVVDFSHLVDSKLGQTVKNLATLFNEINNLPFKQ
                     NYIILFDEIDSIVLDRVNQNDLREMGRVTSAFLKELDRLSPEIVLIATTNLFENLDKA
                     VTRRFDAIIDFDRYTDEDKVEVATIILNELLKQFKNVARDLKLFKKIINSANVIPNPG
                     DLRNSIRTSLAFSDPSDPHDYQKRLLRSLHNGRNLSISKLSKLGFTVREIEILTGISK
                     SSVSRELSED"
     gene            14761..16944
                     /locus_tag="VW348_001515"
     CDS             14761..16944
                     /locus_tag="VW348_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HEU9746397.1"
                     /translation="MGPITIPKKTIITLEHLKYLHFSLEETKTYWEKNNIIDGILISI
                     YYNRIVAKSNRINGYFNVGGGNPFPNDTIVGAKFNDEKTKHIVTHYISRDALNKTITV
                     LSKIIEVFEEHFDRAITCEMFSDSSTFASINFSEYGISKSKFQQYLRDSCFIENFGVE
                     HTTVSDIQNSIVTFYDVHTDIFRLLNKLNIDISEANIMNQTTVLLDEKNIELLLSKAP
                     YLVSMIVEDFSKLSVDDFSLDNNDLKINLPSPMNEPVVGVIDTLFDKRVYFNEWVEYH
                     DFVSPDISKDSQDYKHGTAVTSLIVDGANLNPNLDDGCGNFRVRHFGVSLQSGFNSFT
                     IIKQIKEIVSQNADIKVWNLSLGSNDEIRENFISAEGALLDEIQFENDVIFIIAGTNA
                     SVINGKRKRIGAPADSLNSIIVNSVDFNNQSVSYSREGIVLSFFVKPDVSYYGGGNGD
                     FINVCEPLGLGRVAGTSFAAPFIARKMAYLIHIMGLSREEAKALLIDAAIPWNDKKTF
                     TDLSLIGNGIVPIKMDDILSTPDDEIKFIVSDISRAYDTYNYDFPVPISSESYPYVAK
                     ATMCYFPNCSRKQGVDYTNTEMQLTFGRLKSDGIKSINKDNQHAEDTPGYVRENAARN
                     IFRKWDNVKHIGESFTSRKRAKAILNPSNPQWGMSIKTIERLKSGDGQGVRFGVVVTL
                     KELNGVNRIEDFIQQAELRGWLVNRLQVEAQVDLFNSLNEEIEFE"
     gene            16995..18011
                     /locus_tag="VW348_001516"
     CDS             16995..18011
                     /locus_tag="VW348_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU9746398.1"
                     /translation="MNITYIVGNGLDLQYGLKTRYRDFYEFQNKVYISRTENEEKYSN
                     FIYESLFSDKVNDYENWSDFELSIGKLTKDNDLISSSIEIKEKFIDDFSEVVDDLREY
                     LRIQQEKNLEKGNAIDFISTLDDMRTSLPVINQPAIDKKYNENPHQDDIVNIVTLNYT
                     HVIDKLYNGSAKSFRNQLRANLYNFYIEPPIHAHGTVDVCTVLGVSDEIQISNSLEEQ
                     KESLIKSLVLKNYRENMDVKNSDIIKNSDIIILYGVSLGETDRYIWSQIAERSISGSV
                     PVIIYHYVPHFDPGNPIRAKRLYRNVEDKFIQNSGIDLELEKKLRDNLIVVIGKTIFD
                     LIER"
     gene            18026..18976
                     /locus_tag="VW348_001517"
     CDS             18026..18976
                     /locus_tag="VW348_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEU9746399.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARLAELTDFMDLGELKIGTTVLA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEMIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRESAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            18978..19721
                     /locus_tag="VW348_001518"
     CDS             18978..19721
                     /locus_tag="VW348_001518"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEU9746400.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLTQLDQ
                     FDSIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            19732..21528
                     /gene="pepF"
                     /locus_tag="VW348_001519"
     CDS             19732..21528
                     /gene="pepF"
                     /locus_tag="VW348_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEU9746401.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            21775..22329
                     /locus_tag="VW348_001520"
     CDS             21775..22329
                     /locus_tag="VW348_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEU9746402.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRDDLSNQGL
                     HYLSKEKDTTGFSSQYGWVHAFAHGADLLTEVVCHPDFPKNRVHEVFDILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDELKEAIQSFQY"
     gene            22440..23108
                     /locus_tag="VW348_001521"
     CDS             22440..23108
                     /locus_tag="VW348_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEU9746403.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
BASE COUNT         7382 a         3808 c         4901 g         7150 t
ORIGIN      
        1 tttcgattgt tattattata taattttaaa aaatcaaatt ctttaattgt tgctattata
       61 taatttttaa aattaaaaat ataatcttta gacttgaatt tgattctgta ttcacgccct
      121 caatagacgg taaaataaga aaattgttta tatattgtct ccgtagtgtt attatacgaa
      181 ataaaagatt ttaggaaaag tcgttatatc atgctatacc tattctttgt ggtataattg
      241 caagaggttt aatccgataa tttataaaga gagaaagata ttcatgagag atttattatc
      301 taaaaaaagt cataggcaat tagaattatt agaattatta tttgaacata aacgttggtt
      361 tcatcgttct gaactagcag agttattaaa ttgtacagaa cgtgcagtca aagatgatct
      421 atcccatgtt aaatctgctt ttcctgactt gatttttcat tcttctacta atggtatacg
      481 cattattaat accgatgata gtgatattga aatggtttac catcatttct ttaaacattc
      541 aactcatttt tcgattttag aattcatctt ctttaatgaa ggttgtcaag ctgagagtat
      601 ttgtaaagaa ttttatatca gttcatcttc gctctatcgt attattagcc aaatcaataa
      661 agtgattaaa aggcaatttc aatttgaagt cagtctgacc cctgttcaaa tcattggaaa
      721 tgagagagac attcgttact tttttgcaca atatttttca gaaaaatatt atttcctaga
      781 atggccattt gaaaattttt catcagagcc actatctcaa ttgttagaat tggtttataa
      841 ggaaacaagc tttccaatga atttgtcaac gcatagaatg ctaaagttgc tcctagttac
      901 gaacctatat agaataaagt ttggtcattt tatggaagta gataaagatt cttttaacga
      961 ccaaagtttg gattttttaa tgcaggcaga aggaatagaa ggtgttgctc agagttttga
     1021 atcagaatac aatatctctt tagatgaaga agttgtttgc caattatttg tgtcttactt
     1081 tcaaaaaatg tttttcatag atgaaagtct ctttatgaaa tgcgtaaaaa aggatagtta
     1141 tgttgaaaaa tcttaccatc tattgagtga ttttattgat cagatttcag tcaagtatca
     1201 gattgaaatg gagaataagg ataatctgat ttggcatctg cataataccg cacatctgta
     1261 tcgtcaagag ttgtttactg agtttatttt atttgatcaa aaagggaata caatcaggaa
     1321 ctttcaaaat atttttccaa aatttgtttc agatataaaa aaagagcttt ctcactattt
     1381 agagactctt gaggtttgtt ctagttcaat gatggtaaat catctatctt ataccttcat
     1441 cactcatacc aaacatttgg tgattaattt gctacaaaat cagcctaaac taaaggtttt
     1501 agttatgagt aattttgatc agtatcatgc aaaattcgtt gcagagacac tttcttatta
     1561 ctgtagcaat aattttgaac tggaagtttg gactgaatta gaattatcaa aggaatcttt
     1621 agaagattca ccttatgata tcattatttc taattttatt attcctccta ttgaaaataa
     1681 gagactcatc tattcaaata atataaacac ggtctcactc atatacttgt taaatgccat
     1741 gatgtttatt cgattagatg agtaaccaaa aataacaaaa aaacgctatt tcgcgtttga
     1801 actgtacctc aaaagttaga cagaaaaaat ctaatttttg gggtgttttt gttaagaaaa
     1861 gaccttcaat catttaagca aaatgtacat ctagatttat agccctctaa aactcttgct
     1921 ttttttgtag aagatacgaa aaaagccata aaaccaaggc ttttcctgtt ttatgtagat
     1981 gtttacacat gaaaattgaa gtattttcaa aagctaattg gagtgatttt attcatgatg
     2041 ggataaatga tctggccaaa aatgattgag aaatagttgc ttaaaaagca tttgcatgat
     2101 actatatatt gaaaggaggt gataatatgg tagaacaaag aaaatcaatt accatgaaag
     2161 atgttgcttt agaagcagga gttagtgttg gaactgtttc acgtgtaatt aataaagaaa
     2221 aaggcattaa agaagtaact ttgaaaaaag tggaacaagc gattaaaact ttgaattaca
     2281 ttccagatta ctatgctaga ggaatgaaaa aaaatcgaac agaaacgatt gcaatcattg
     2341 taccaagtat ctggcatccc ttcttttcag aatttgctat gcatgtggaa aatgaagtct
     2401 ataagagaaa taacaaatta ctcttatgtt ctataaatgg tacaaataga gagcaagact
     2461 atctggagat gttgcgtcat aataaagttg atggagtggt tgccattacc tatagtccaa
     2521 ttgaacatta cttgacgtca ggaattccct ttgttagtat tgaccgcaca tactcagata
     2581 ttgccattcc ttgtgtttca tcagataatg atgcaggtgg aagagaagca gctaaacaat
     2641 taattagtaa aggatgtcag catttagcct ttgtgggcgg acataataca accattaatg
     2701 aaaccaaacg tcgtagaatt tcatttgaaa agtatgtcca agagcataaa atacctctta
     2761 gtatttttga tttggatgag acagttactg actattatgg aaagctagag agtttcttgg
     2821 aagaaaattc ttctatagat ggaattttta caatcaacga ttttacagct ttggatgtga
     2881 ttgaaatact agaaaaaaat ggcaaacgta ttcctcatga tgtccaaatt attggatacg
     2941 atggaattaa aatggctgga gatagagatt atctactttc aactattgaa caaccattgg
     3001 aagaaatggc aaaagaagcg gttcgtattt tgtttgatat aattgatgga aagactgtta
     3061 atttgcagac aatcctacca gtaaaatttg ttgaaggaaa aacaacaaaa aatgaaaata
     3121 agtcttgaca gaaagcgcta tcaatgatag aatgaattca gataaaaaga tttattttta
     3181 aaacaaaaat gaaacgtttc aaaaaaagaa ataaaaagac agcgccaagc gctatctttt
     3241 atagaaaaaa tgaaacgttt caaaaaaagg aggttgctat gaatagcaaa gcgaagcaag
     3301 tttctctttg ggaaagaatc aagaaacaaa aactcttgtt attgatgact gtccccggtt
     3361 tagttttaac ctttatcttt aaatacatcc ctatgtatgg ggttttaatc gcatttaaag
     3421 attacaatcc tttaaaagga attttaggga gtgattggat tggtttttct gagtttacaa
     3481 aattcatatc ctctcccaac tttggtatct tgttagccaa cacattaaaa ttaagtatct
     3541 atggtttatt gcttggcttt ttaccaccaa tcattcttgc gattatgctc aatcaactct
     3601 tgagtgaaaa agtcaaaaaa cgaattcagc tcattttata cgcaccaaac tttatctcag
     3661 tcgttgttat tgtcggtatg attttcctct tcttttcagt gggaggacca atcaacaatt
     3721 ttctttctat gtttggaatg aaggctgact tcttgacaaa tccagacttc tttagaccct
     3781 tatacatctt tagtggtatc tggcaaggaa tgggctgggc ttcaacgctc tacacggcaa
     3841 cattggtaaa tgtagatcca gccttagtag aagcagctcg actggatgga gccaatatct
     3901 tccaacgaat ctggcacatt gatattccag ctcttaagcc tattatggtt atccaatttg
     3961 ttttagctgc aggtggaatt atgaatgtcg gatatgaaaa agcattcttg atgcagacat
     4021 cgttaaattt gccaacttct gaaattatct cgacatatgt ctataaagtt ggtcttgtat
     4081 caggagacta ttcttactca acagcggttg gtttgtttaa tgcagtgatt aacgtagtat
     4141 tgcttgttgc agttaaccaa atcgttaaac gcatgaataa tggtgaagga atttaaggag
     4201 gaaagtatga aaaattcgat tatggataca aaatttgata gacgtatctt actcttaaat
     4261 aaaatcatta ttgtctttat cgttttgatg actttgcttc ctttacttta tatcgtcgta
     4321 gcatccttta tggatcctaa ggttctggtt agtagaggga ttagctttaa tccagccgat
     4381 tggactgtag aaggttacca gcgtgtattc agtgaccaat ctattctaag aggttttatc
     4441 aattctctac tatactcttt tggatttgca gctttaacag tattgctatc tgtgtttaca
     4501 gcttatcctc tttctaagaa agacttggtt ggacgtcgtt ggattaacta cttcttgatt
     4561 gtgactatgt tctttggtgg tggtttagtc ccaacttact tgctcgtaaa agaattggga
     4621 atgctcaata ctccatgggc tatcattgtt ccaggtgctg tcaatgtttg gaatattatt
     4681 cttgctaggg cctatttcca aggattgcct gaagaattag ttgaagctgc tgtcattgat
     4741 ggagcgaatg acttgcagat tttctttaaa atcatgcttc ctcttgcaaa accaattatg
     4801 tttgttctct tcctctatgc ttttgtagga cagtggaact catactttga tgcaatgatt
     4861 tatatcaagg atccaaactt ggaaccattg caacttgtac ttcgtaaaat tctcattcag
     4921 agccaaccag gtcaagacat gattggagca caagcggcta tgaatgaaat gaaacgttta
     4981 gctgaattga ttaaatacgc aactattgtc atttccagct tgccattgat tgttatgtat
     5041 ccattcttcc aaaaatactt tgataaagga attatggctg gttcacttaa aggataaaaa
     5101 aagaaaaaat aaaaggagtt ttctcatgaa attcaaaaca ttctcaaaat cagcagtttt
     5161 gttgacagct agtttagcag tacttgcagc ctgtggctca aaaaatacag cttcaagtcc
     5221 agattataag ttggaaggtg taacattccc gcttcaagaa aagaaaacat tgaagtttat
     5281 gacagccagt tcaccgttat ctcctaaaga cccaaatgaa aagttaattt tgcaacgttt
     5341 ggagaaggaa actggcgttc atattgactg gaccaactac caatccgact ttgcagaaaa
     5401 acgtaacttg gatatttcta gtggtgattt accagatgct atccacaacg acggagcttc
     5461 agatgtggac ttgatgaact gggctaaaaa aggtgttatt attccagttg aagatttgat
     5521 tgataaatac atgccaaatc ttaagaaaat tttggatgag aaaccagagt acaaggcctt
     5581 gatgacagca cctgatgggc acatttactc attcccatgg attgaagagc ttggagatgg
     5641 taaagagtct attcacagcg tcaacgatat ggcttggatt aacaaagatt ggcttaagaa
     5701 acttggtctt gaaatgccaa aaactactga tgatttgatt aaagtcctag aagctttcaa
     5761 aaacggggat ccaaatggaa atggagaggc tgatgaaatt ccattttcat ttattagtgg
     5821 taacggaaac gaagatttta aattcctatt tgctgcattt ggtatagggg ataacgatga
     5881 tcatttagta gtaggaaatg atggcaaagt tgacttcaca gcagataacg ataactataa
     5941 agaaggtgtc aaatttatcc gtcaattgca agaaaaaggc ctgattgata aagaagcttt
     6001 cgaacatgat tggaatagtt acattgctaa aggtcatgat cagaaatttg gtgtttactt
     6061 tacatgggat aagaataatg ttactggaag taacgaaagt tatgatgttt taccagtact
     6121 tgctggacca agtggtcaaa aacacgtagc tcgtacaaac ggtatgggat ttgcacgtga
     6181 caagatggtt attaccagtg taaacaaaaa cctagaattg acagctaaat ggattgatgc
     6241 acaatacgct ccactccaat ctgtgcaaaa taactgggga acttacggag atgacaaaca
     6301 acaaaacatc tttgaattgg atcaagcgtc aaatagtcta aaacacttac cactaaacgg
     6361 aactgcacca gcagaacttc gtcaaaagac tgaagtagga ggaccactag ctatcctaga
     6421 ttcatactat ggtaaagtaa caaccatgcc tgatgatgcc aaatggcgtt tggatcttat
     6481 caaagaatat tatgttcctt acatgagcaa tgacaataac tatccaagag tctttatgac
     6541 acaggaagat ttggacaaaa ttgcccatat cgaagcagat atgaatgact atatctaccg
     6601 taaacgtgct gaatggattg taaatggcaa tattgatact gagtgggatg attacaagaa
     6661 agaacttgaa aaatacggac tttctgatta cctcgctatt aaacaaaaat actacgacca
     6721 ataccaagca aacaaaaact agaggttgat tatgggagat aagaaataca cagtagaaaa
     6781 agccaatcgt tttatagcag aaaataaaca tctcgttaat actcaatata agcctgaaga
     6841 acatttttca gctgagattg gttggatcaa tgatccaaat ggatttgtct attttcgtgg
     6901 agaataccat ctcttttatc aattctatcc atatgatagt gtttgggggc ctatgcactg
     6961 gggacatgct aaaagtaagg acttggtgac ttgggagcac ttgccagtgg cacttgctcc
     7021 tgaccaagat tatgaccgaa atggttgttt ctcaggctct gccattgtca aggatgatcg
     7081 cctctggctc atgtacactg gacatatcga agaagaaacc ggtgtccgcc aagtgcaaaa
     7141 tatggcattt tcagatgacg ggattcactt tgaaaagatt tcccaaaatc cagttgcaac
     7201 tggatcagac ttgccagatg agttgattgc tgctgatttc cgtgatccaa aactctttga
     7261 aaaagatgga cgctattact ccgtagtagc tgccaaacat aaggataatg tgggctgtat
     7321 cgttctacta gggtccgata acctagtaga atggcagttc gaatccatct ttttaaaagg
     7381 ggtagaacac caaggcttta tgtgggaatg cccagattac ttcgagttag atgggaaaga
     7441 ttgccttatt atgtcaccca tgcgttatca gcgtgaggga gactcatatc ataacatcaa
     7501 ctcatcgctt ttgttcacgg gtaaggtaga ttggggagaa aaatgtttta tcccagaatc
     7561 agttcaagaa attgatcatg gccaagactt ctatgcgcct caaacattgt tggacgatca
     7621 aaatcgtcgt atcctgattg cttggatgca gacatggggg cgtacccttc caacccatga
     7681 ccaagaacac aaatgggcat gtgccatgac tttacctaga attttaagat tggaagatgg
     7741 caaactaaga caattccctg ttaaaaaagg ccaatatcaa atccaaatag ataaagattg
     7801 tcattaccac ttaggaaatg atatagatta tcttgaattt ggttatgata gtaatgcgca
     7861 gcaagtttac attgatcgta gccatcttat tcaaaaaatt ctaggtgaag aagaacagga
     7921 cactagtcga cggtatgtag atattgaagc taaagaattg gaagttgttc tagataaaaa
     7981 ttccatcgag atttttgtca atcaaggtga agcaagcttg actgcaactt attacttaac
     8041 ggtgccagct gagctatcac gaattgatta aaaattaagt tatttctcct aaagaaaaag
     8101 ttctctttct aaaatagtgg aaagaggact ttttgtgttt tgggtatata agcttagttt
     8161 atggtatttg taaaattggt gttggattat gatttaagct agttttctaa agaatttgaa
     8221 aaaaatttta tttaagcaaa aaaaaaccct tggttccaag gcttttcctg ttgtatttat
     8281 atgcccccta cagggatcga acctgtgacc cacggattaa gagtccgctg ctctgccagc
     8341 tgagctaagg aggcaaagaa aaaagctgta ttggtgccga aacttcacgg tttgtattga
     8401 acccgcgcaa ttaagcaggt gggcaactcg ctctaactga agctgtttcc gtgtgagacg
     8461 gcctacatgc tgttagaaga cttttgtttc cctaataata caaaaaatag tcggtcaaca
     8521 cttaagtgtg aagtcgtaca ccacagcgtt tctatactta tatgatacca ctttttcaaa
     8581 aaaaatcaag aggaaagtgc aattttttga aaaggatttc agatttttcg caaacggtcg
     8641 atagcttcct ttctttgagc caaagcccgt tcatatttac cagtatcttc tgcttggaaa
     8701 tagtgatgat tacgaatttt ttctggcaga tagtcttgct tgacccaatt tccaggatag
     8761 ttgtgtggat agagatagtc ttgggcattc cccagttcct tgcttccact gtagtgccca
     8821 tcacgtaggt gtcgcggaat aggcaagtgc cctgatgttt tgaggtcagc aagtgcctta
     8881 tccatagcta cataggctga gttggatttt ggagaaaggg ccaaatcaat cacgacattg
     8941 gcaatgagaa tgcgggcttc tgggaaccca atcttctggg cagcatccag agcagtcacg
     9001 gtatgaatct gggcctcagg attggctaag ccgatatctt cataggcgat aacagtcaag
     9061 cgacgagcga gactaggcag atccccagcc tcaatcaagc gggcagtata gtggagactg
     9121 gcatccacat ctgagccacg aatagacttt tgcagggcag atagaacatc atagtgaccg
     9181 tctccatcct tgtccatagt gatgtagctt ctctgaagac tattttccat gatgtctaag
     9241 gtgatgtggc gaatgccctc gtcattctca ggggtagaga gaacagctaa gtccagtgag
     9301 ttaaaggcag agcgaaggtc tccgtttgta gaggttgcga tgaaatccag cgcatcctca
     9361 tctagttcta ttggaaaatc aaaaccacgt tcagggttac ttagagctat ctgcagggcc
     9421 tctttgacgt cttggttaga cagaggttcc aactcgaaaa tttgaactcg gctacgaatg
     9481 gcaggagtga cagagaagaa aggattttca gtcgttgctc caatcatgat gaccagtcca
     9541 ctttccaaga gaggcaagag gaagtcttgc ttggtcttat ctagtcgatg aatttcgtct
     9601 agcaatagga cgagaccacc agaaaattta gcttcttccg agatttcttg cagtcgcttt
     9661 ttactatcaa ctgtcgcatt gaaagttcga aaggcatact tggtcgttcc agcgatggca
     9721 gaggcaatac tggttttgcc gattccagga gggccatata gaatcatgga ggacaggcgg
     9781 ttggcttcca ccatgcggcg gatgattttt ccaggtccga ccagatgctc ctgaccgatg
     9841 acctggtcga tggttttagg gcgcatgcga agcgcgagat tgtctggcat agcagtcctt
     9901 tctagcgtgg atttgagtag aatgactcat ctactatatc ttactatgtc cattctagcc
     9961 tattagttgt gatatttcaa tggttttgta ataatcaggg agtgagatag aatctttttt
    10021 actatttaat ttaatgagga gaggtatcag catgagagat ttgattttcc ttaaagctca
    10081 aaataggata gttgagccta aagaagtgga agtgctgact tgagaaataa tattgctgaa
    10141 tgtcattgta tgaactataa tgaaaagaga ggtgataagt aatggaaatg atggaccaag
    10201 tcaggaaatt ttgattttta caaaacaaat tcgtcattgg attcttagtg atcaagttat
    10261 ttcagggaaa agaaaacttt tcttccggga agatactcca aaagagattt tagatttgta
    10321 cgaaaacatt aaatctaaac ttgattttgc ttaccaataa gtttattcta ataatgggtt
    10381 gaaaaaatat gaaaaataga ataattgatg tttttgaagt agtaaatcgc atccttgtaa
    10441 taactgttga aaatcctgat ttcgaagact tgagagttaa tcatactcaa tgaaaatcaa
    10501 agagcaaact aggaaactag ccgcaggctg tacttgagta cggtaaggcg acgttgacgt
    10561 ggtttgaatt tgattttcga agagtatcag tttgtaaaaa ttggagataa aaaatataga
    10621 gtacgcagtg ttcctatgat tcattcaact ccgcctcaat ctgtcttaga tcgagatact
    10681 tttacaattg actatacaga tgatgaattg ctcgataaag aagcagtttt tactactcat
    10741 tagaaaaata ggtctgaata aattggcttc ccttagaacc acatctaggg gcttttatgt
    10801 ataatagaat aataagtatc actcctttac aatacgtgta acacgtgtta taatggtgtt
    10861 gtcaggaggt aaaagcgcta tgcctatgac acaaaaagag atggttaaac tccttacggc
    10921 ccatggttgg ataaagacta gaggcggtaa aggctcccat attaaaatgg agaagcaagg
    10981 ggaaagactt atcacaatcc ctcatggtga gctgaataag tacactgaaa gagggataag
    11041 aaagcaagct gggttgtaaa attcagcccc tgttttttga tatggaggta gtgaaatgtt
    11101 agttacgtat ccagctttat tttattatga cgacacagac ggaacagaag cgacttattt
    11161 tgtccatttc ccagattttg aatactcagc tacacaagga gaggggattt ctgaggcttt
    11221 ggctatgggg tcggagtggc tagggataac tgttgcagat ttgatagaga gtgatggaga
    11281 gttacctcag ccatcagata tcaatagctt gtctttaatt gataatgatc cttttaaaga
    11341 tgatgaagat ttcgtgtcaa cctatgacct tgataaatct tttatttcta tggtatctgt
    11401 tgatgtatca gaatacctag gaagtcagga acccataaaa aagactttga ccataccaaa
    11461 atgggcagat aagttgggac gagaaatggg acttaacttt tctcagactt tgacagacgc
    11521 tattgcagat aagaaagttc aagcctaaga ttaagcgtgg tatcgtggta atagtcaata
    11581 aaaaagcacg tccacttgtg ctagttactc gcctattgat tttatagatt tattagccct
    11641 ttcgcgggct ttttatattg atttttatga gaaatgaaga aatcagactt ttaagaaaat
    11701 cactgatacc aagggtttaa atgaggtaat atggtataat taggacataa aataattttg
    11761 tggtaagatg gtagtatcta ttttagcata tttccgagca atcggggcga ttaaagagtc
    11821 gcatagaaag aggacaaaat ggcaacatac ggatttttag atgttttaga ggaagagttg
    11881 gacaagaact ttccctttga ctttgagatt agctgggaca aacgcaacca tgcggtagaa
    11941 gtgagttttc tattggaagc gcaaaatgct gcaggtgtgg agatggtgga tgaagacgga
    12001 gaggttttat cagatgacat tctttttgag gaagcggtcc ttttctacaa tcctgccaag
    12061 tcaacagtca atgaggaaga ctatttgact gttattcctt acctgcctaa aaaaggattt
    12121 tcccgtgaat ttttagctta ttttgcgctt ttccttaaag atactgctga ggttgggcta
    12181 gatgtcctca tggacttttt ggaagaccca gaagcagagg aatttgtcat ggaatggaac
    12241 caagaagtct ttgaagaagg aaaagttggc ttggaagagg gagaatttta tccttatcca
    12301 agatactagg agttggttgg aggtgttatg aagaaaattg ggacttattt ggtttatgtg
    12361 ctagcttttg tctttattat gctagctttt gcttgtggaa caatcgcatt tgcagagttg
    12421 gggtattccg cagttttagc ctttactttt ggttatgcct tcgctcttct aagcatgtat
    12481 ttaatcttta ttcttcatga gctgggtcat gctttttgtg gctacttgac aggctatcgg
    12541 ctggtggctt ttggattagg acattttatt ttgaccaaaa agtcaggcag gtttcatctt
    12601 agtagaacag ccattctgaa aaatgttggt gctcaataca ttggtttaaa agaggatgaa
    12661 agcgatcaaa gaatcatcct gatgctttca ggaggcttga tggttcatct cggcttgata
    12721 ttattggcga tagtgtttgg atttttgaca agaagctggt attttgcagg gacttggatt
    12781 tttcttaatt tatctttctt cctaaataac attttgccag tcgacatcac cgatggagca
    12841 aaaatttggg aattactaca acaccctgaa aataccaaat acgcctacct ggtattgaga
    12901 cattctgctc aaactttgct ggctcctcaa gaatatgatt tgaaagactt tgttcaagca
    12961 gttcctgagg atgcacgagg gagttttgcg gatggtgtat taggtatgca aggtgaagtt
    13021 tccattttgg aagggaagga agaagtagct aaacagcagt ttcaagcatt acttgagagg
    13081 acaactactc cgatgatgca gacagttgcc caactatccc tgcttcatat cgccttgttg
    13141 gaaggagatt ttgagcaagc ggagcaatat gctagtattc gacaggtcaa atcgtttctg
    13201 tctctcaaac tgtccaatct tcaagtgata caagcttggt atcaatttaa ggtaaagaaa
    13261 gatgtagatc gaactcgtaa ggctctcaag attgctagac agaaaatgga tagtagtcga
    13321 atgttgaggg acgagaaacg ctattatgaa aacttgttag cagagctgga aaaggaaatg
    13381 ttagaaggaa ctgaagatgg aactagaaat ttctgatttc ccaggctgta agattgcttt
    13441 gttttgtggg gataagctct tgactatctt acgtgatgat aaggcaagta ttccctgggc
    13501 caatatgtgg gaactgccag gtggtggaaa gagtgtcagg gaaaatctga tatagttttg
    13561 tattaaaaga atatcctttc aaggttattc ttttttaatt ttgtcccaaa ataattgact
    13621 ttgtcccgaa aatatagtat tatttgtgta aggaggaatg aatcatgaaa aaatcagatg
    13681 ttcttgattt aataaagtat cattatgagg gcagagagac agaatttaga aatcaatcca
    13741 tagcaattgc tcggaacttc aataaacatg gtgatacaca aatagcacaa tatattatgg
    13801 ggttaatgtc tcaaagtgat agattcatgc cacaaataga aaatcctagt gagtatttga
    13861 ctcctgctaa actagatatt ggtcctctcc cattgcctct ttcaattatg aatgatttaa
    13921 aaggaataat aaacgctgtc aatcatcata ttggaataaa taaattttta tttgtgggat
    13981 ctccaggtac tggaaaaact gaaagtgtaa agcaggtggc tagacttatt ggcaaggaat
    14041 tacttgtagt agatttcagt cacttagtag atagtaagct agggcaaaca gtcaaaaact
    14101 tagcaactct ttttaatgaa atcaataatc ttcctttcaa gcaaaattat atcatcctat
    14161 ttgatgaaat tgattccata gtgttggata gggttaatca gaatgattta agagaaatgg
    14221 gacgagtgac ttctgccttt ttaaaggagt tggataggct gtcaccagaa attgtattaa
    14281 ttgcaacaac aaatcttttt gaaaatcttg ataaagcagt tacgagaaga ttcgatgcca
    14341 taattgactt tgaccgttat actgatgaag ataaagtaga agtagctact attattttaa
    14401 atgagttatt aaagcaattt aagaatgtag ctagagattt aaaattattt aaaaaaatta
    14461 tcaatagtgc caatgtaata ccgaatcctg gtgatttgag aaactcaata agaacgtcat
    14521 tggcatttag tgacccatca gatccgcatg attaccaaaa acgcctgcta agaagtttgc
    14581 ataatggtag aaatttatct atttctaaat tatcgaagct aggttttact gttagagaaa
    14641 ttgagatttt gacaggtatt tctaagagta gtgtatcacg agagttaagc gaggattaaa
    14701 atgaatacat tattgacatt acgaggtaaa agttttacac aaaaatcaag aaataatggt
    14761 atgggaccaa taactatacc caaaaaaaca ataattacat tggaacattt gaagtatctt
    14821 catttttcat tagaagagac gaaaacatat tgggagaaaa ataacattat cgatggtatt
    14881 ttgatcagta tttactataa tcgaattgtt gccaaaagta accgtattaa tggctatttc
    14941 aatgtaggag gagggaatcc attccctaat gatactattg tgggagcaaa attcaatgat
    15001 gagaagacaa aacatattgt tactcattat atttctagag atgctcttaa taaaacaata
    15061 accgttttaa gtaagataat tgaagttttt gaggaacatt ttgatagagc gataacatgt
    15121 gagatgtttt ctgattcatc aacgtttgct tctataaatt tttcggagta tggtatttca
    15181 aaaagcaaat ttcaacagta tttgagagat tcttgcttta ttgagaattt tggagttgag
    15241 cacactactg tttctgatat tcaaaattct atcgtgacat tttatgatgt ccatacagac
    15301 atttttagat tactgaataa attaaatatt gatatttcag aagctaatat catgaatcag
    15361 accacggtct tgcttgatga aaaaaatatt gaattgctac tatcaaaagc gccctatctt
    15421 gtctccatga ttgtggaaga tttttctaag ttatctgtag atgatttttc tttagataat
    15481 aatgatttaa aaataaatct tccatctcca atgaacgaac cagttgttgg cgttattgat
    15541 accttatttg acaaaagagt ttactttaat gagtgggtag aatatcatga ttttgtctca
    15601 cctgatatta gcaaagatag ccaagattac aagcatggga cagctgtgac ttctttaatc
    15661 gttgatggag ccaatttgaa ccctaatctg gatgatggtt gtggaaattt tagagtgagg
    15721 cattttggtg tgtcactaca aagtggattt aattcattta caatcataaa acagataaaa
    15781 gagattgttt ctcagaatgc tgatattaag gtttggaatc tttctttagg gtccaatgat
    15841 gaaataagag aaaattttat ctctgcagag ggagcattat tagacgaaat tcaatttgag
    15901 aatgatgtaa tttttatcat agctgggaca aatgcttcag taataaatgg gaaacgcaaa
    15961 agaataggtg ctcctgctga ttcacttaat tctataatag taaattctgt tgattttaat
    16021 aatcaatcag tgtcatattc acgagagggt attgttttat cattctttgt taaaccagat
    16081 gtgtcatatt atggaggagg aaatggtgac tttataaatg tttgtgaacc tctaggatta
    16141 ggtcgtgtag ctggaacaag ttttgcggca ccttttattg caaggaaaat ggcctatctc
    16201 attcatatta tgggacttag ccgagaagaa gcgaaggctt tgctaattga tgcagcaata
    16261 ccctggaatg ataagaaaac attcactgat ttatctttga taggaaatgg tattgttcca
    16321 ataaaaatgg atgatatttt atctacacct gatgatgaaa ttaaatttat tgtgtcagat
    16381 atctctaggg cttatgatac ctataattat gattttccag tacctatttc tagtgagagt
    16441 tatccatatg tagctaaagc aacaatgtgt tatttcccta actgctcaag aaaacaaggg
    16501 gttgattata caaatactga gatgcagctt acttttggta ggttaaagtc agacggtatc
    16561 aaatcgataa ataaagacaa ccagcatgcc gaagataccc caggatatgt gagagaaaac
    16621 gctgctagaa atatatttag gaaatgggat aatgtcaagc atattggaga gtcgtttact
    16681 tctcgaaaga gagctaaagc aattttaaat ccatctaatc ctcagtgggg gatgagtatt
    16741 aaaacaatcg aacgtttgaa aagcggtgat ggacaaggag tacgttttgg tgtagtagtt
    16801 acattaaaag aattaaatgg ggttaatcgt attgaagatt ttattcagca agctgaatta
    16861 cgcggttggc tagttaatag attgcaagta gaagctcaag tagacctctt taatagttta
    16921 aatgaagaaa ttgaatttga atagtggata ttttatcctt attttagatc ttaggaacac
    16981 aagagggcaa agatatgaat attacttata tagttggaaa tggtttggat ttgcaatatg
    17041 gtttgaaaac aagatatagg gatttctacg aattccaaaa taaggtttat ataagtagga
    17101 cagagaacga ggaaaaatat tcaaatttca tttatgagtc tctattttct gataaagtaa
    17161 atgattatga aaattggtca gattttgaat tgtcaattgg taaattgaca aaagataacg
    17221 acctcatctc ctcaagtata gaaataaagg agaaatttat agatgatttt agtgaagtag
    17281 ttgatgattt aagagaatat ctacgcatac aacaagaaaa aaatcttgag aaaggtaatg
    17341 caattgactt tataagcact ctagatgata tgaggacctc tctccctgta attaatcaac
    17401 ctgctatcga taaaaaatac aatgagaatc cacatcagga cgacattgta aatatagtaa
    17461 cacttaatta tacacatgta atcgataaat tatataatgg gtcagcaaaa tcattcagga
    17521 atcaattacg agctaatctt tataattttt atattgagcc accaattcat gcacatggga
    17581 cggtggatgt ctgcacggtt ttaggggtta gtgatgaaat acaaatttca aatagtttag
    17641 aagaacaaaa ggaatcccta ataaaaagtt tagttttaaa aaactataga gaaaatatgg
    17701 atgtaaagaa tagtgatatt ataaaaaatt ctgacatcat tattctctat ggggtttctt
    17761 tgggagaaac tgataggtat atctggagtc agattgctga acgatcaatc agcggttctg
    17821 ttcctgtcat aatttaccac tatgtacctc attttgatcc ggggaatccc attagagcaa
    17881 aacgcctata tagaaatgta gaagataaat tcatacagaa tagtggtata gacttagagt
    17941 tagagaaaaa attaagagac aaccttattg tcgttattgg taagactatt tttgatctaa
    18001 tagagaggta attttaaaaa acaaaatgga aacatggcaa gagttaaaag ttacagtgaa
    18061 gcgtgaggga gaggagttgg tttccaatct cttgattgag ctgggagcgc aaggtgttgc
    18121 gattgaagac agtatggact atgtgggaaa tgttgaccgc tttggcgaga ttttcccaga
    18181 ggtggagcag caagaagaaa tcgtagtgac agcctactac cctgacacgg tggatgtgac
    18241 agtggttgag gcggacttgc aggctcgctt agcagaattg acggatttta tggatttggg
    18301 agagttaaaa ataggtacga ctgtcttggc tgaggaagac tgggcagata actggaagaa
    18361 atactatgag ccagctcgta tcactcatga tttgaccatc gttccctctt ggacagacta
    18421 tgaggcgact gcgggggaaa tgattatcaa gctggatcct ggcatggctt ttggtactgg
    18481 aacccaccca actaccaaga tgagcctttt tgccttggaa caggttcttc gtggtggcga
    18541 aacggtgcta gatgtgggga ctggttcagg ggttctctct attgccagct cgcttctggg
    18601 ggctaaagaa attttcgcct atgacctaga tgatgtagca gttcgtgttg ctcaggaaaa
    18661 tattgaactt aaccctggaa tggaaaatat ccacgttgct gctggagact tgcttaaggg
    18721 tgttgagatt gaggcagatg tgattgtagc taatatcttg gcggatattc tcattcatct
    18781 gacagacgat gcctatcgtt tggtcaagga tgaaggctac ctgatcatga gtggcattat
    18841 caaggacaag tgggacatgg tgcgcgagtc ggctgagtca gctggatttt tccttgaaac
    18901 ccacatggtt caaggggaat ggaatgcctg tgtctttaag aaaaccaagg atatttctgg
    18961 tgtgattgga ggctagcatg cagcagtatt ttgtaaaagg cagtgctatc tctcctgtca
    19021 ctatcgagga caaggaaacc agtaagcata tgtttcaggt tatgcgcttg aaagaagagg
    19081 atgaggttac cttagtcttt gatgatggca tcaagcgctt ggcgcgcgtg ctggatatgg
    19141 aaaatcgtca gtttgagttg gtccaagaat taaatgacaa tgtggaacta ccagttcaag
    19201 tgaccatcgc atctggattt cccaagggag acaagctgga gttcatcgct caaaaagtaa
    19261 ccgaactggg tgctagccaa atctgggcct ttcctgcaga ctggtcagtt gccaagtggg
    19321 atggcaagaa attgggtaaa aaagttgaaa aactagaaaa aattgccctt ggagcagccg
    19381 agcaaagcaa gcgtaatatt gtaccaagta ttaaactttt cgagaaaaaa gcagattttc
    19441 taactcagct ggaccagttt gactctatca tagtagccta tgaagaatca gctaaagaag
    19501 gagaagccgc tgcgcttctg caagcagtca ctggtcttga aacaggagcc aaactgctct
    19561 ttatctttgg tccagaaggc ggtctctcac ctgcagaaat cgaaagtttt gaagctaagg
    19621 gagccgtttt ggtaggccta ggtcctcgta ttttgcgagc agaaacagca ccgctttacg
    19681 ccttatcagc ccttagtgtt ttagtagaat tagagaaata agaggaagaa aatggaacaa
    19741 aaacaccgtt cagaatttcc agagaaggaa ctttgggatt taacagctct ataccaagac
    19801 cgtgaggatt tcttgcgtgc aatcgagaaa gctcgcgaag acatcaacca gtttagccgt
    19861 gattacaagg gcaatcttca cacttttgag gatttcgaga aggcctttgc ggaattggaa
    19921 cagatctaca ttcagatgag ccatattggc aactatgctt ttatgcctca gacgacggac
    19981 tatagcaatg acgaatttgc aaatattgct caagctggga tggaatttga aacagatgcc
    20041 agcgtagcct tgaccttctt tgacgatgcc ttggtggtag cagacgagga agtcttggac
    20101 cgtttgggtg aattgcctca cttgacggca gctattcgtc aggccaaaat caaaaaagcc
    20161 cactatctag gggctgatgt ggagaaggcc ttgaccaatc tcggtgaagt tttctatagt
    20221 ccgcaggaca tttatactaa gatgcgagct ggggattttg aaatggctga ctttgaagcc
    20281 catggcaaga cctataaaaa cagctttgtc acctatgaga atttctacca aaatcacgag
    20341 gatgctgagg ttcgtgagaa atccttccgt tccttctcag agggacttcg taagcaccaa
    20401 aatacggctg cagcagccta tctggctcag gtcaagtctg aaaaactctt ggctgatatg
    20461 aagggatacg actctgtctt tgattatctt ctagctgaac aagaagtgga ccgtgtcatg
    20521 tttgaccgcc agattgacct catcatgaag gactttgcac cagtcgctca gagatacctc
    20581 aagcatgttg ccaaggtaaa tggtcttgaa aagatgacct ttgcagactg gaaattggac
    20641 ttggacagcg ccctcaatcc tgaagtgact attgacgatg cctatgattt ggtcatgaag
    20701 tcggtagaac ctttggggca agaatattgt caggaagttg ctcgttacca agaagagcgc
    20761 tgggtggact ttgctgctaa cagtggcaag gattccggtg gttatgcggc ggacccatat
    20821 cgcgtacacc cttatgtact catgagctgg acaggccgtt tgagcgatgt ctataccttg
    20881 attcatgaaa tcgggcattc tggtcaattc atcttttcag acaatcacca aagctatttc
    20941 aacgcccaca tgtcgaccta ttatgttgaa gcaccgtcga ccttcaatga attgctactc
    21001 agtgattact tagagaacca gtctaatgac ccacgtcaaa aacgcttcgc tctggctcat
    21061 cgcttgacag acacctactt ccataatttc atcacccacc tcttggaagc cgccttccag
    21121 cgtaaggtgt atacattgat tgaagaagga gaaaccttcg gagcaagcaa actcaacagc
    21181 attatgaagg aagttttgac agatttttgg ggcgatgcca ttgaaatcga cgacgatgca
    21241 gctttgactt ggatgcgcca agctcactac tatatgggct tgtatagtta cacttactct
    21301 gctggtcttg tcatctcgac agctggttac cttcatctta aaaactcaga aactggagct
    21361 gaagactggc tcaatctcct caaatcaggt ggtagcaaga caccacttga gtcagccatg
    21421 attatcggtg ctgatatttc aacagacaaa ccactccgtg ataccatcca attcttgtct
    21481 gacacagttg accagattat cgcctacagt gctgagttgg gggagtaagg ggaatagaaa
    21541 aattttctag aatgatgttt atgggcttgt taagcgtcat tctatttgtc ttagttgtag
    21601 ctattttcaa aaatgtcgtt gaaggtcgtg atgttaaatt tgaacttact gtagaactgg
    21661 tattgatagt tatttacgtc attttatatc agattgtatt taattgagaa ttcaatattg
    21721 agtcatttaa gactgccttt ttgaacagtt gctagaaatg tagaggtatt gaccatgtat
    21781 caagatttac taagaaaaat agcagaagaa aaaccaaatt ataaccagga agaaatccag
    21841 tggttgtttg atcatttggg aaatccttct ccagaaattc gtgatgacct ttcaaatcaa
    21901 ggcttgcact atctttcaaa agaaaaggat acaacaggtt tctcaagtca gtatggttgg
    21961 gttcacgctt ttgcacatgg agccgattta ctgacagagg tggtttgtca tccagacttt
    22021 cctaaaaaca gagttcatga agtatttgat atacttggcc aactatttaa aagaatgtcg
    22081 attcgcttta cagatgatga ggattggcgt ttagcaagag tgatctatga acctatttta
    22141 caagggaagt tggagcaaga acaagtagct tcttggataa aaactgttga ttttccgata
    22201 gaagaaaggg aggattttta caaattttcc aactttagat cctgtctggt ggaagtctat
    22261 gtccaacttg accagagaaa tagtttacaa gatgagttga aagaagctat ccagtctttt
    22321 caatactaga gattagctaa tagttctatg attttcaaaa aatttccaat caattttctt
    22381 gaaacccttt cctacttttg atagactagt atctagtttt tgaaaaaagg agaaagaaaa
    22441 tgaaaaaatt tgttgctgag ttaatcggta cgttcatgct tgtgttcgtt gggacaggag
    22501 ctgttgtttt tggaaatggt cttgatggcc ttggtcacct tggaatcgcc tttgcctttg
    22561 gtttggcaat cgtggtggca gcctactcaa tcggaactgt ttcaggtgct cacttgaacc
    22621 cggctgtttc gattgctatg tttgtaaaca aacgtttgtc atcttcagaa cttgtaaact
    22681 acatccttgg tcaggttgtt ggagctttca tcgcttctgg cgctgtcttc ttcctcttgg
    22741 ctaactcagg tatgtcaact gctagtcttg gtgaaaatgc cttggcaaac ggtgtcactg
    22801 tctttggtgg tttcttgttt gaagtcatcg caactttctt gtttgtattg gttatcatga
    22861 ctgtgacttc agaaagcaag ggcaatggcg cgattgctgg tttggtaatc ggtttgtcat
    22921 tgatggcgat gattcttgtc ggattgaaga ttactggact ttcagtaaac ccagctcgta
    22981 gcttggcacc agctgtcttg gtaggcggcg cagcccttca acaagtttgg attttcatcc
    23041 ttgcaccaat cgctggtgga gttcttgcag cccttgttgc aaaaaatttc cttggaacag
    23101 aagaataatt gaaactcaaa aagccttgct cctcatcttg aggaacaggg ctttttcgta
    23161 tgatactctt cgaaaatctc ttcaaaccac gtcagcttca ccttgccgta ggtatggtta
    23221 ctgacttcgt cagttctatc c
//
LOCUS       DAVKMJ010000035        22982 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000035 DAVKMJ010000000
VERSION     DAVKMJ010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22982
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.035"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            467..712
                     /locus_tag="VW348_001522"
     CDS             467..712
                     /locus_tag="VW348_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746404.1"
                     /translation="MGIYGRKTIAMKHFFAGIGEIHFLLFLLYLSMSASPIIGLVIGY
                     TKINLINSIIIALGMILALILVLSRVYRKYFYRDDDD"
     gene            869..1927
                     /locus_tag="VW348_001523"
     CDS             869..1927
                     /locus_tag="VW348_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746405.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALRDLSKQYLNKNISELQDGSFEDGIQDAVASKQIVVINEFIACLNSRCVPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            2241..3218
                     /locus_tag="VW348_001524"
     CDS             2241..3218
                     /locus_tag="VW348_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746406.1"
                     /translation="MKNKRYFFDTILIILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKSLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKRDCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            3595..3969
                     /locus_tag="VW348_001525"
     CDS             3595..3969
                     /locus_tag="VW348_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEU9746407.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            4177..5079
                     /locus_tag="VW348_001526"
     CDS             4177..5079
                     /locus_tag="VW348_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746408.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTNTLKDKIQKSDLSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWSNKVDKIRIHLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            5135..5488
                     /locus_tag="VW348_001527"
     CDS             5135..5488
                     /locus_tag="VW348_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEU9746409.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKSDCQGICAALAMSPGT
                     FIALAGSAVLTKKLINYIKFGGLGGWLIGAAAGVLATAAGKIAYCIGYGALNRGCDIS
                     GNPYPWDGFISATVR"
     gene            5485..6213
                     /locus_tag="VW348_001528"
     CDS             5485..6213
                     /locus_tag="VW348_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746410.1"
                     /translation="MNNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IGEDFATKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNRVLALI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKAKEYELFKNSK"
     gene            7345..7848
                     /locus_tag="VW348_001529"
     CDS             7345..7848
                     /locus_tag="VW348_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746411.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLETFKVNFCLTDLHHLF
                     GLHKITRDYASQTKPAIQDGVFILEDFRNILLYNDVIERISLYEFIGDIFYSKITSCC
                     IVAKDLSKNTMKLDVIFFEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTD
                     VKEMKWL"
     gene            8135..10300
                     /gene="pspA"
                     /locus_tag="VW348_001530"
     CDS             8135..10300
                     /gene="pspA"
                     /locus_tag="VW348_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein A"
                     /protein_id="HEU9746412.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTLVRAEEAPVANQSKAEK
                     DYDAAVKKSEAAKKDYETAKKKAEDAQKKYDEDQKKTEEKAELVRKADEKRQKANLAV
                     QEAYVKFQEAQREFNESPSRKKSDAKKKLDDASAHIEEVKLKQKEADANFNKEQAKVI
                     PEASDLAVTKQKAEEAKKEAEVAKEKYDKAVQEVEVEKNKILEQDAENEKKIDVLQNK
                     VADLEKGIAPYQNKVAELNKEIARLQSDLKDAEENNVEDYIKEGLEQAIADKKAELAT
                     TQQNIDKTQKDLEDAELELEKVLATLDPEGKTQDELDKEAAEDANIEALQNKVADLEN
                     KVAELDKEVTRLQSDLKDAEENNVEDYVKEGLDKALTDKKVELNNTQKALDTAQKALD
                     TALNELGPDGDEEETPAPAPKPEQPAEQPKPAPAPQPAPAPKPEKTDDQQAEEDYARR
                     SEEEYNRLPQQQPPKAEKPAPAPKPEQPVPAPKTGWKQENGMWYFYNTDGSMATGWLQ
                     NNGSWYYLNSNGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGAMATGW
                     LQYNDSWYYLNANGAMATGWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGAMAT
                     GWLQYNGSWYYLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTWYYLEASGAM
                     KASQWFKVSDKWYYVNGLGALAVNTTVDGYKVNANGEWV"
     gene            10700..11821
                     /gene="mnmA"
                     /locus_tag="VW348_001531"
     CDS             10700..11821
                     /gene="mnmA"
                     /locus_tag="VW348_001531"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEU9746413.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLATAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTNLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            11962..12417
                     /locus_tag="VW348_001532"
     CDS             11962..12417
                     /locus_tag="VW348_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9746414.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNEKTEDAVVREVKEELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            12427..14340
                     /gene="mnmG"
                     /locus_tag="VW348_001533"
     CDS             12427..14340
                     /gene="mnmG"
                     /locus_tag="VW348_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEU9746415.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            14544..14621
                     /locus_tag="VW348_001534"
                     /pseudo
     CDS             14544..14621
                     /locus_tag="VW348_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(14719..16398)
                     /locus_tag="VW348_001535"
     CDS             complement(14719..16398)
                     /locus_tag="VW348_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEU9746416.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(16400..16633)
                     /locus_tag="VW348_001536"
     CDS             complement(16400..16633)
                     /locus_tag="VW348_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEU9746417.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            16913..17128
                     /locus_tag="VW348_001537"
     CDS             16913..17128
                     /locus_tag="VW348_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746418.1"
                     /translation="MYNLFAFAIGVRLLAFIVFVACVYGGNLLFAKLERRQTKFLWKM
                     TFVTLYSLFLLLVTYVVWFVFYFELNA"
     gene            complement(17451..17603)
                     /gene="cibB"
                     /locus_tag="VW348_001538"
     CDS             complement(17451..17603)
                     /gene="cibB"
                     /locus_tag="VW348_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEU9746419.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(17605..17790)
                     /gene="cibA"
                     /locus_tag="VW348_001539"
     CDS             complement(17605..17790)
                     /gene="cibA"
                     /locus_tag="VW348_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEU9746420.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            17968..18651
                     /gene="tsaB"
                     /locus_tag="VW348_001540"
     CDS             17968..18651
                     /gene="tsaB"
                     /locus_tag="VW348_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEU9746421.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPH
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLSFEEVLEKVKGTSQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            18648..19085
                     /gene="rimI"
                     /locus_tag="VW348_001541"
     CDS             18648..19085
                     /gene="rimI"
                     /locus_tag="VW348_001541"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEU9746422.1"
                     /translation="MIEIKRIQQHPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            19075..20085
                     /gene="tsaD"
                     /locus_tag="VW348_001542"
     CDS             19075..20085
                     /gene="tsaD"
                     /locus_tag="VW348_001542"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEU9746423.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHELPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFANLDLNAKPSLAFDT
                     ME"
     gene            complement(20125..21431)
                     /locus_tag="VW348_001543"
                     /pseudo
     CDS             complement(20125..21431)
                     /locus_tag="VW348_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(21823..21903)
                     /locus_tag="VW348_001544"
     CDS             complement(21823..21903)
                     /locus_tag="VW348_001544"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9746424.1"
                     /translation="MLPLPTYSPEYNPIEKIWAYIKNISE"
     gene            complement(22104..22430)
                     /locus_tag="VW348_001545"
     CDS             complement(22104..22430)
                     /locus_tag="VW348_001545"
                     /inference="COORDINATES: protein motif:HMM:NF013842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746425.1"
                     /translation="MEKVDRDKLKIYIETHPDAYLTEIAAEFNCPPTTIHYALKAMGY
                     SLKKSRTYCEQDPEKVNRFLKELNHLSYLTPIYIYETGVKTYFYLEYDRALSRQLVSL
                     EEDIII"
     gene            22667..>22982
                     /locus_tag="VW348_001546"
     CDS             22667..>22982
                     /locus_tag="VW348_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEU9746426.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLK"
BASE COUNT         7163 a         3922 c         4868 g         7029 t
ORIGIN      
        1 gacatatcaa ctaggtcatt agattttatt gaagatataa attaaaaacg aggttgggaa
       61 aaaactcaat ttgaaagtga gattgagtaa atctttctat ctatataacg tatatcatca
      121 atatttttga acacctgata atatgcactt ttcttatttt aaagattttt tgcctttatt
      181 catttcttga atgaattgga gagatgactt tatttaggtg tttgacatta ctatagatag
      241 gatttagcag tactaatatg aactcatatt ataggtgtag acttaaattt tggaagcaag
      301 ctaaaggata tcttatctag gtaactaagt gctataacaa gatatattgg tggagttagt
      361 atggcaacta ttactaatgc tcttaatatt gtggctactg ttgctgaagt cttctcatta
      421 ggaggagcca ttgcatatgg tttagatatc gtagacggta aatttgatgg gtatttatgg
      481 gcgtaaaact atagctatga aacatttttt tgcaggaatt ggtgaaattc attttttgtt
      541 atttttatta tatctaagca tgtctgctag tccaattatt ggactagtga ttggatatac
      601 taaaataaat ctaataaatt ctattattat agctcttggt atgatattgg cattaatttt
      661 ggtattatca agagtgtata gaaaatattt ttatagagac gatgatgact aaagttttta
      721 tcaataattt gggctccttg tcaactgtag tgggttgaat aaaagctaac gtctggggaa
      781 gggtttaaag ctttgcttta tcaaatattg acttacagag ttgctctatt gtattgatgc
      841 attcttagta aataatatgg tgttttaaat gaaagatgat cagaaatatt tattagcggg
      901 actttattcg cttctagttg caatatttta ttttccattg attgattcca aggggatttt
      961 tgtaagtata ttgatggcgg ttttactttt atatttaata tacttcattg caacagtcat
     1021 tcatattgtg ataattaagt ttataagaaa aaaatctttt aagtatttgg ttctatatcc
     1081 atttacttat gatgggagct ggagatttca acctataaac ttactctact ttccagaaat
     1141 ggtgagagat gtcattccga ttaatttagt tcaagaatat tgccaaggac aaccttacgg
     1201 actgttaaaa aagatgctga aaagaattcg attgtcacga gagatatctt tactcctggc
     1261 taccattatc gtctattttt ttacgcatag aattctacct ctttcagtat ttacgttcat
     1321 attttcttac atattgctat ttgcacaatc ttatttgggt ggtaataccg cttggattgg
     1381 aaatagaaga ttaataatag atgatgaatt tgaaaaaatc ttgctttcaa aaagttatat
     1441 aaaagaaata tcatctgcac gatactcaga atacttgaca tgtgaataca aaaactttac
     1501 accaatcata ttgttagcta tttttgaaaa tttgcttgac tcctacttgc ttcagaatca
     1561 gagtgaggtt gacttagata ttttttataa agttttacct ttgctttata aagaaaaata
     1621 tactatggga ttcaattact ttgtaagttt aaattattta ctatataagg ttggattttt
     1681 gggaatcatt tacgataatg aagcattaag agatttgtca aaacaatatt taaacaaaaa
     1741 tatttcggaa ttacaagatg gttctttcga ggacggtata caagatgctg ttgcctctaa
     1801 acaaatagta gttataaatg aatttatagc ttgtttaaat tccagatgcg tgccatccca
     1861 atatgataga tttttttata aagatagacc ttatattttt tccagaaaga gtcctattaa
     1921 ggggtgaaaa tttgttacat ttggattaac aagtgtccta gggattagaa ataactctag
     1981 tatagctaga tatttttgag taactagaaa tatcattagt ctacccatat gattgccaga
     2041 aaagatggct gatgaatctt atttatactg ttgcagtagg cgttgtctag gataaataag
     2101 ctatcttgat gggggagatt ggaataattt tagtagaaac attaaaggat tatggacaag
     2161 tagcgcagga ttaggtgatg caatgtgcta agttggcttg gtgttagcag tagtattatt
     2221 taacaatgga aagtagacta atgaaaaata agcgttattt ttttgacaca attttaataa
     2281 ttttactgct tataagcacg atattttgtg tcagcccagt atttataaaa ttggacatct
     2341 taggaactcc ctctcatgcc atcttaacct ttgtattggc gataccgtta ttctatattt
     2401 tgtctcaatg cttacatact ttgctattac tagtttcctc aatcttttgt aaattaagac
     2461 caatttattt ttattttata tttgtgatca ttataggagc taggaaatac tatcgaattc
     2521 tctttcacca actaatggga tttagtccag gaatagcagt gttttataag gagagtcaaa
     2581 caactaagaa tctgtttaaa ttttactact tcttgtactt tacaacacta atttcatact
     2641 attttttctt tacttttgtg tatgacaaat cgttgctttt gcctcttatt ccattttcta
     2701 ttatcatagc attagtacaa aaactttata gaattgagaa tcaacaatta tttctgttaa
     2761 aatcaaaagt actaacaata ctggaatcta agagggattg tgagtttaat cttcaggatt
     2821 atcatgaaat ttggaaattg caatcaaaat ctgagttgcc atgcgtggct ttatcttata
     2881 tcagtttgat caagccatat ctttcagaga gtgtgcgtga acaaattgat ttattagaag
     2941 ttaagcgatt taaaaaaata aatcatccaa tatcacttta tggtatgttg gatgttataa
     3001 aattaaatct atatttacgg cattataatg aaaaaaataa atatgaatca atgttaaaga
     3061 aaattttaga ggtaagacca gactttgttt taatcgagca gaatattgat gatagtttaa
     3121 atagctcgca acccttatct ttatctttag ccatttcaga aatccaactt ttgcttgaag
     3181 tgtatatggg gatcaaacat gtttcaatta ggagataaaa ccagaataat atttgccatt
     3241 ataggggcaa gttgcatatt agtcagtatg tatcttattc cacttattaa aactgagaat
     3301 aaattttggg aaatactttt atttatatta ggtgtattgc taattggaat tgcgttacta
     3361 agtcaaaaaa aataaatttt gaaatagtat tagtgagttc gcaattattt attgctagtg
     3421 gtttagaact gttaagtttc aaacaataat tgattttaaa ccttaggtaa cctataaaaa
     3481 caaataaggt agagaaagga tatcttatat aggtagctaa gtgataaaaa cacagtcgtc
     3541 tatcacttgt taggaaacta tcctaactat gcttaataaa aaaggagaaa ataaatggaa
     3601 ctcgtattac caaataatta tgttgctctt gagcaagaag agatgatgta tcttgatggg
     3661 ggattttcta ttctgagatg gcctgttgca acagccatta atatagcttt taatggtgtt
     3721 ttaggtggag gagcaatcag tctagttaga aattatattc gtaattatgg tttgcggcga
     3781 gttacaagcg caattgctgg agcagctgca agatatgttg gggtacgagt tgcaaataga
     3841 gtggcaggat ttgcactgtc tgctattaat ggatttgcag cttggatgtc aattggcgat
     3901 gctattacaa caatctgggc caacaatgat gtaaatagga gagacccaaa tttaaacgcc
     3961 ttgtggtaac tagatatggg tattaaaatg gaaaaaattt ttgttattat tttttttgta
     4021 tgtctattta tatcatccat aactttttta gcctatgatt ttgttagcga agaaataaaa
     4081 aaattgatta tttggatgaa tgtcgttttt ttgattttaa tcatagcaat gataatttat
     4141 ccaaaattaa gaaaatgata aggacactgt aaaattatga tacgtaaact aatcattttt
     4201 ttattaatgc tccctctttt tgtcttgtgg ctagagttgc atgtcctagt gaataactta
     4261 ctattgaatc tagaatctcc ccttgatttt gtgattagta tgagtcttgc tttctgtagt
     4321 ttgattttat caaaaatagt tttagacata ctatacgcat tgaaagattt gtacaagaaa
     4381 gaagctctta ttacgatttt tccttttatt tttataggca ggaagaaagt aaatgtgagg
     4441 ttctcgccct atttttcatt ccatcgtaaa agtttgtcgc ctgatgattt aagatctagg
     4501 attatatgga gttttattct tgaaattgct attatcctag tatttatttt aaaaattcct
     4561 tttgcaatca tcatgcttac tacaatattt ttctggacta taatggatat caatcatctc
     4621 gtttttaata agacggaatt tcttttcaat caaaataaat gggaaaaaga agattcgttt
     4681 gaaagtgatt tgacaaatac gttaaaggat aaaatacaaa aatcagatct cagttattct
     4741 gacttaatgt ctcttcagct gtatgatgcg atgaatcaat ctaccttttt aacggatagt
     4801 gaactctttg aggatattct gagtaaaatt gaagattctc ataacaccct tctgtgtaca
     4861 ggtcttgtcg agttactgct gtatgagatt tctattagta acaataacaa ctggtccaac
     4921 aaggttgata aaattaggat acacctcatc agaatcaatc aattagattt tttctattat
     4981 acaagttggt taaggcaaaa ttttgatttc tgtatgaata gagagtatca taaaatgaaa
     5041 tctcggaaat tattactgag taataaaaag atagtttaag ttcgtcctat ttgtaaaaca
     5101 aatgaaacaa tttcaactaa ggaggagaaa acaaatggaa cttgtattac caaataatta
     5161 tgttgtgatt gatgaagaag aaatgatgta tcttgatggg ggggcttatt taagcaagag
     5221 tgattgtcaa ggaatttgtg cagctttagc tatgagccca ggaactttta tagcattagc
     5281 tggatctgca gttttaacta aaaaactaat aaactatatt aagtttggag gtcttggagg
     5341 ctggcttatt ggtgcagcag caggtgtatt ggctacagca gcaggaaaaa tagcttactg
     5401 tattggatat ggtgctctta atagaggttg tgatattagc gggaaccctt atccttggga
     5461 tggattcata tctgcgacag taagatgaat aatgtagata agattcgaaa aatacatatt
     5521 atcgtatgtt ggatgtatat atttttatca ttcagggcga ttataaatga cacggagtat
     5581 tttttgctta tttttttagc ttttatctac tcaatagtat cactacctct atattctgtg
     5641 aaaaataaaa tagtatctat ctgtctagcc ataaattcga ttctgttaat gagtttcccc
     5701 attttaatca ataagttttt cccagaaagt tttttgactt ataccgtatt aataagtgtt
     5761 tttatcctag agttagcaat ctttcattta attggggaag attttgctac taaattgact
     5821 aacgaatata agaaaattag tcagtttaga agcaaggtgt ctcaatctcc ttggataaaa
     5881 tatttagaga tttctagttt tatattaact atatttccat ctattcttta cggtacagtt
     5941 gataatcgtg tattggctct tatctttttg ataaaaattt gtgtagatac tacgataaaa
     6001 tttttattca tcagattatt tgacacaagt actttaatga agaggagaat attttttctt
     6061 ttcgcattgg atgttatagc ttacttattt ttaggatatc ttttagtgat tcaaaaagca
     6121 ggctatttgt tttcggtttt acttcttttt tctaattttt cagttccatt tatcaaagca
     6181 aaggaatacg aattatttaa aaatagcaag taatagaaac ataggttaaa tcttagaacg
     6241 gcttaaaatc agatatgata aagggaaata gtcttatcta ggtaactaag tgctacaaac
     6301 acagtcgagg atcacttgtt aggattacat tttaatcatg cttaataaga atggagaatt
     6361 cctatgggga ttgtattact ctgaagtttc gaatacctta gttctcgtga ttttgagctg
     6421 ttctagcttt agaatccttc agaatgtaaa attttaagca gtcaaagact tagaatagcc
     6481 tggaaacatt tattttatag caattctagg cttagaattg ctcatatata tgtatttgag
     6541 ctgctcgata gttaggacag ctctattctg agaaatctga gctatcaatg cttcagaata
     6601 gtatttcgca aatggttttt attgaagagg tgattgtttt atgatagtct aaaataaaac
     6661 tgatttaatg gagtaaatgg agaatcgtca catgaaacat ttttttgcag gaattggtga
     6721 gataaaactt gttggctact tattgtatat atgtgtagga ctagcccctc tttttcatat
     6781 atatgtcata ggttcggaac tgagttttgt gaaaatagtg ttatctattt tgggagttat
     6841 atttgtaagt atgttaacta ttgctcgaat ttatcggact tttctataaa gaatagtttg
     6901 gacttgaact gtatctaaaa acagaggttg gtcgattatc agcctctttc ttgtcgttga
     6961 aaagagtgag atatattgac ttttgaaaaa aatgtcataa ttgagttggg ataaacctaa
     7021 aagtaatata gtagattgaa tctggaatag tccgttatga ctgttaaaat atttctagaa
     7081 attaatttga ctttcctaat cgatttgttc acatcttgtt tcaatctact atactttctc
     7141 gttaaaccgt tcggcaattc atggtgacat ggacacatag tagtaagcac attatgtggc
     7201 ttggcagagc taaaaactgt tcccttgcga taagcctaat aagcacaaca tagggagtta
     7261 gagaagccga ctctaatcaa ccactttggg cagtagtgag aactgccccg tgctttttat
     7321 tttgagaaaa tatggagttt gtcgttgaaa ttacttgatt gtattttgga ctatcaagaa
     7381 agattcaatg gaaaaacatg tcaagtatca acgaattata agtatttaga gactttcaaa
     7441 gtgaattttt gcttgactga tttacatcat ttatttggct tacacaaaat cacacgagat
     7501 tatgctagtc aaacaaaacc tgctattcaa gatggtgttt ttattttaga agattttaga
     7561 aatatcctat tgtacaatga tgtaatcgaa aggatatctt tatatgagtt tataggtgat
     7621 attttctatt ctaaaataac aagttgttgc atcgtagcta aggatttatc taaaaatact
     7681 atgaaattgg acgtcatatt ttttgaggat aaaaataaaa gatccgcagt tttaggttta
     7741 cgaagagaca aaagcggagt atttaaacca gttaccctac attttacaag cgctaagaaa
     7801 tatgctaaag ttcgtaaaac agatgtgaaa gaaatgaaat ggctataaag attgtccgca
     7861 ggcttaagct tgcgtttttt gttgtttaac gaaattaaaa aaacaagctc tctcatcgga
     7921 aatgttttta taggaatgaa ggaagatgat gctatgttta aaaagagaat cgaaaagggc
     7981 aaaagtagtg tctttatctt tttggagtag aagcttatga tatagaaatt tgtaataaaa
     8041 atgtaatata aaacatttga caaatattta cggggggagt atacttaata taagtatagt
     8101 ctaaaaatga ctatcagaaa agaggtaaat ttagatgaat aagaaaaaaa tgattttaac
     8161 aagtctagcc agcgtcgcta tcttaggggc tggttttgtt acgtctcagc ctactttggt
     8221 gagagcagaa gaagctcccg tagctaacca gtctaaagct gagaaagact atgatgcagc
     8281 agtgaaaaaa tctgaagctg ctaagaaaga ttacgaaacg gctaaaaaga aagcagaaga
     8341 cgctcagaag aaatatgatg aggatcagaa gaaaactgag gagaaagcag agcttgttcg
     8401 aaaagcggat gaaaaacgtc aaaaagcgaa tttggcagtt caagaagcat atgtaaaatt
     8461 ccaagaagca caaagagaat ttaacgaaag tccaagcaga aaaaaatctg atgctaaaaa
     8521 gaaattagat gatgcatcag ctcatattga agaggtaaaa ttaaaacaaa aagaggcgga
     8581 tgcgaatttt aataaggaac aagcaaaagt aattcccgaa gcaagtgact tagctgttac
     8641 taaacaaaaa gcggaagaag ctaaaaaaga agcagaagta gctaaggaaa aatatgataa
     8701 ggcagttcaa gaggtagaag tagagaaaaa taaaatactt gaacaagatg ctgaaaacga
     8761 aaagaaaatt gacgtacttc aaaacaaagt cgctgattta gaaaaaggaa ttgctcctta
     8821 tcaaaacaaa gtcgctgaat taaataaaga aattgctaga cttcaaagcg atttaaaaga
     8881 tgctgaagaa aataatgtag aagactatat taaagaaggt ttagagcaag ctatcgctga
     8941 taaaaaagct gaattagcta caactcaaca aaacatagat aaaactcaaa aagatttaga
     9001 ggatgctgaa ttagaacttg aaaaagtatt agctacatta gaccctgaag gtaaaactca
     9061 agatgaatta gataaagaag ctgcagaaga tgctaatatt gaagctcttc aaaacaaagt
     9121 tgctgatcta gaaaacaagg ttgctgaatt agataaagaa gttactagac ttcaaagcga
     9181 tttaaaagat gctgaagaaa acaatgtaga agactacgtt aaagaaggct tagataaagc
     9241 tcttactgat aaaaaagttg aattaaataa tactcaaaaa gcattagata ctgctcaaaa
     9301 agcattagat actgctctta atgaattagg tcctgacggt gatgaagaag aaactccagc
     9361 tccagcacca aaaccagagc aaccagctga acaaccaaaa ccagcgccgg ctcctcaacc
     9421 agctccagca ccaaaaccag aaaaaacaga tgatcaacaa gctgaagaag actatgctcg
     9481 tagatcagaa gaagaatata accgcttgcc ccaacagcaa ccgccaaaag cagaaaaacc
     9541 agctccagca ccaaaaccag agcaaccagt tcctgcacca aaaacaggtt ggaaacaaga
     9601 aaacggtatg tggtacttct acaatactga tggttcaatg gctacaggtt ggctccaaaa
     9661 caacggttca tggtattacc tcaacagcaa tggcgctatg gctacaggtt ggctccaata
     9721 caatggttca tggtattacc taaacgctaa cggcgctatg gctacaggtt gggctaaagt
     9781 caacggttca tggtactacc tcaacgctaa tggtgctatg gctacaggtt ggctccaata
     9841 caacgattca tggtattacc taaacgctaa cggcgctatg gctacaggat ggctccaata
     9901 caacggttca tggtactacc tcaacgctaa cggtgctatg gctacaggtt gggctaaagt
     9961 caacggttca tggtactacc tcaacgctaa tggtgctatg gctacaggtt ggctccaata
    10021 caacggttca tggtactacc tcaacgctaa cggtgctatg gctacaggtt gggctaaagt
    10081 caacggttca tggtactacc tcaacgctaa cggttcaatg gcaacaggtt gggtgaaaga
    10141 tggagatacc tggtactatc ttgaagcatc aggtgctatg aaagcaagcc aatggttcaa
    10201 agtatcagat aaatggtact atgtcaatgg tttaggtgcc cttgcagtca acacaactgt
    10261 agatggctat aaagtcaatg ccaatggtga atgggtttaa gccgattaaa ttaaatcatg
    10321 ttaagaacat ttgacatttt aattttgaaa caaagataag gttcgattga atagatttat
    10381 gttcgtattc tttaggtacc tatcttatga tttcaggaag tgtcattaaa aaaacgactc
    10441 cttttctcta acttgaaaaa tagattagag aaaatgggtt gttttattta ttatagttat
    10501 ttgaatgaag ataagaagag ggtatactca cgtcattcac atgatctgta tattgactat
    10561 aagttttaaa aaacaatttt taagctcttc cttgtcttct ctaaccaagc gtgttataat
    10621 gaatactgct caagcgacct tcaatcgtga agcacacacg accttcaatc gtgaataaac
    10681 gaatagatgg agacttacca tgagtgataa ctctaaaaca cgtgttgtcg tggggatgag
    10741 tggtggtgtt gattcgtcgg tgacggctct tttgctcaag gagcagggct acgatgtgat
    10801 cggtatcttc atgaagaact gggatgacac agatgaaaac ggcgtttgta cggcgaccga
    10861 agattacaag gatgtggttg cggtggcaga ccagattggc attccctact actctgtcaa
    10921 ttttgaaaaa gagtactggg accgcgtttt tgagtatttc ctagcggaat accgtgcagg
    10981 gcgcacgcca aatccggacg ttatgtgcaa caaggaaatc aagttcaagg cctttttgga
    11041 ctatgccatg accttggggg cagactatgt agcgactggg cattatgctc gagtggcgcg
    11101 tgatgaggac ggcactgttc acatgcttcg tggcgtggac aatggcaagg accagaccta
    11161 tttcctcagc caactttcgc aagaacaact ccaaaaaacc atgttccctt tgggacattt
    11221 ggaaaagcct gaagtacgca gactagcaga agaagcaggc ctggcgactg ctaagaagaa
    11281 agattcgaca gggatttgtt ttatcggaga aaagaacttt aaaaacttcc tcagcaacta
    11341 cctgccagct cagcctggtc gcatgatgac tgtggatggt cgcgatatgg gcgagcatgc
    11401 aggtcttatg tactatacaa tcggtcagcg tggcggactc ggtatcggtg ggcaacacgg
    11461 cggtgacaat gccccttggt tcgttgtcgg aaaagatcta agcaagaata ttctctatgt
    11521 aggacaagga ttctaccatg attcgctcat gtcaactaac ctagaagcca gtcaagtcca
    11581 ctttactcgt gaaatgccag aagagtttac gctagaatgt acggctaaat tccgttaccg
    11641 tcagcctgac tctaaggtga ccgtccatgt caaaggagac aaggcagaag ttatctttgc
    11701 ggaaccacaa cgcgcgatta caccaggaca ggcagttgtc ttttacgatg gcgaagagtg
    11761 tctaggtggc ggtttgattg acaatgctta ccgcgatgga caagtttgtc agtacattta
    11821 gattgacaaa ttttctcaat ttgctacaat aataacagca atagaaatga tggtcaaagc
    11881 tcatggatgt tgcaggcttt tttgtcctgc acttctttgt agttttgact gtttttgtgt
    11941 cgtttaaggg aaaggacaag aatgactcaa caagactttc ggacaaaagt agacaatacg
    12001 gtttttggtg ttcgggcgac agccttgatt gtccaaaatc acaagcttct agtcaccaaa
    12061 gacaagggca agtattacac tatcggcggt gcgattcaag ttaacgaaaa aacggaagac
    12121 gcggtagtcc gtgaagtgaa ggaagaacta ggtgttaaag ctcaagctgg gcagctagct
    12181 tttgtggttg aaaatcgttt tgaagtggac ggcgtttcct atcacaatat cgagtttcat
    12241 tatctggtgg atttgcttga agatgccccg ttgaccatgc aggaagatga gaaaaggcag
    12301 ccctgtgagt ggattgactt ggataagctt gaggatatcc agctagttcc agccttttta
    12361 aaaacagccc taccagattg ggaaggccaa ctaagacaca ttcatcttga ggaataggag
    12421 agaaacatga cttatcattt tactgaagaa tacgatatta ttgtaattgg tgcgggacac
    12481 gctggggttg aggcttcctt ggccgctagc cgtatgggct gtaaggtcct gcttgcgacc
    12541 atcaatattg aaatgctggc tttcatgcct tgtaatccct ctatcggtgg ttctgccaag
    12601 gggattgtcg tgcgtgaagt cgatgccctc ggtggcgaga tggccaaaac cattgacaag
    12661 acttacatcc agatgaagat gctcaacaca gggaaggggc cagctgtccg tgcccttcgt
    12721 gcgcaggctg acaaggaact ttactctaag gagatgcgca agacggttga aaaccaagaa
    12781 aatctgaccc ttcgtcaaac catgattgat gagattttgg tggaagatgg caaggttgtc
    12841 ggtgtgcgta cagccaccca tcaagaatat gctgctaagg ctgttattgt gacgacaggg
    12901 actgctctcc gtggggaaat tatcatcgga gacctcaagt actcatcagg tcctaaccac
    12961 agcttggctt ctattaacct agctgacaat ctcaaggaac tgggcctcga aatcggtcgt
    13021 ttcaagacag gaacccctcc acgtgtcaag gcttcttcta tcaattacga tgtgacagaa
    13081 atccaaccag gagatgaagc acctaatcac ttctcataca cttcacgtga tgaggattat
    13141 gtcaaggacc aagtgccatg ctggttgacc tacaccaatg gtaccagtca tgagattatc
    13201 caaaacaacc tccaccgtgc gcctatgttt acaggtgtgg tcaagggagt ggggcctcgt
    13261 tactgtccat cgattgagga caagattgtg cgctttgcgg acaaggaacg tcaccaactc
    13321 ttccttgagc cagaagggcg caatactgag gaagtctatg ttcaaggact ttcaaccagt
    13381 ctgcctgagg atgtccagcg tgacttggtt cattccatca aaggtttgga aaatgcagag
    13441 atgatgcgga caggttatgc tattgagtat gatatggtct tgcctcatca gttgcgtgcg
    13501 actctggaaa ccaagaaaat ctcaggtctc ttcactgctg gtcagacaaa tggaacatca
    13561 ggttatgaag aagctgctgg ccaagggatt atcgcgggta tcaatgcggc tctgaaaatc
    13621 caaggcaagc ctgagttgat tttgaagcgc agtgacggtt atatcggggt gatgatcgac
    13681 gacttggtga ccaagggaac cattgaaccc taccgtctct tgacaagtcg tgctgaatac
    13741 cgtctcattc ttcgtcatga caatgctgat atgcgcttga ctgagatggg acgcgagatt
    13801 ggccttgtgg atgatgaacg ctgggctcgt tttgaaatca agaaaaatca atttgataat
    13861 gagatgaaac gcctagacag tatcaaactc aagccagtca aggaaaccaa tgctaaggtt
    13921 gaggaaatgg gcttcaagcc gttgacagat gcggtgacag ccaaagaatt ccttcgccgt
    13981 ccagaagttt cttaccaaga tgtggtggcc ttcatcggac cagctgcaga agacttggat
    14041 gacaagatta tcgaattgat tgaaacagaa atcaagtacg aaggctatat ttccaaagcc
    14101 atggatcagg ttgccaagat gaaacgtatg gaagaaaaac gcattccagc caatatcgac
    14161 tgggatgaca tcgattctat tgcgacggaa gctcgtcaga agttcaaact catcaatcca
    14221 gaaaccatcg gccaagccag ccgtatttcg ggagtaaacc cagcagatat ttctattttg
    14281 atggtgtatc tggaaggtaa aaatcgtagt atttctaaaa ctcttcaaaa atcaaaatga
    14341 tacgtcgtcg gcttcttacg aatgagttca aagcttggct ttgattcatc tccaacctcc
    14401 catagttccc cgaactatgg gagctaactc aagttatgct ttcgcttagc cttctagtct
    14461 gattttcatt gagttttaat ctcaaaagaa agcatagaga aaaacagctc cgaagacggg
    14521 gctgttttgt tgatttgtac tcaatgaaaa tcaaagagca aactaggaag ctagccgtag
    14581 gttgctcaaa gcactgcttt gaggttgtgg atagaactga cgaagtcagc tcaaaacaca
    14641 gttttgaggt tgtggataga actgacgaag tcagtaacat atatacggca aggcgaagct
    14701 gacgtggttt gaagagtatt attcttcatc tggtgtgagg atcatcggga tgatgatcgg
    14761 ttcacgttcg gtattttcat agaggaaggg gcgaatagcg ttgacaatgg caccattgac
    14821 agattgcacg ctagcatcct tatttttcag tgcgatacga atggcattga agaggatacg
    14881 ctggctttgg cgaatcaagt cgccagactc tctcatgtag acaaagcctc ggctgaggat
    14941 gtctggacca gatagaatca tctgcgattt gaagtcaaca gttgcgactg ccagaacgac
    15001 accgtcttca gatagatcgc gacgatcttt gaggacagct gcgccaattt caccgatacg
    15061 atttccatcg acatagatat cttgggcgtt gaaatgacct gcgatacgag ctgagtcagc
    15121 agtaagggca agcacatcgc cattgctcat gataaagata ttgtccttct caacaccagt
    15181 atccactgct agtccagcgt ggactttttg catgcggtat tcaccgtgga caggcatgaa
    15241 gtattttggc ttaatcaagc agagcatgag tttttgctct tgctgaccac cgtgtccaga
    15301 tgtatggata ttgtttactt taccgtggat aacttcgaca ccagcttcag aaatgatgtt
    15361 aatcagcttg ttgacgctag tagtgtttcc agggatggga ctagaagaga agataacggt
    15421 atcacctggt tgtaattgta cttgacggtg ggttccgttg gcgatacgag agagggctgc
    15481 cataggctca ccctgactac ctgtacagag gataagaact tctcctgcag gataatcttt
    15541 gatttcattt ggctcgataa aggttccctt aggagctttg atgtagccaa gatcgattcc
    15601 gttgacaatg gccttttcca tagaacgacc aaagaccgca atcttgcgtc cagtcttaac
    15661 agcagcttct gttgcctgct ggagacggaa gatatttgag gcaaaggatg caaagatgat
    15721 acgtccttca ataccttgga taatcttcat aatggactga ccaacgactt tttcagagtt
    15781 ggtaaaggtt ggtacttccg catttgtcga gtcagacagg agacagagca cgccttcttc
    15841 accaagcgca gccatacgat gcaagtccgc aggttctcca actggagtaa agtcgaactt
    15901 aaagtcaccc gtacagacga ttttcccttg aggagtatga atgacaatcc ccaaaggctc
    15961 tggaatagag tgagtcgttc taaagaaagt tgccttgaga tttttaaagg tcaactcggt
    16021 gttgtggttg atttcgtaaa gtttggcgtt gcgcaagagg ccgtgttctt cgagtttccc
    16081 acggatcaaa gccaaggcaa gcggtccagc gtagataggg acatttgctt gcttgagtag
    16141 gaacggaatc ccaccaatgt ggtcctcgtg tccgtgtgtg attaaaacag ccttgacgcg
    16201 gtcgatattg tccacgatgt aagagtagtc aggaatgaca tagtcgatac caagcaagtc
    16261 atcttctggg aatttaatcc cagcatcgac gatgataatc tcgtcttggt attcaattcc
    16321 gtaagtgttt ttcccgattt ctcctagacc accgatggca aaaacgccga cttcttcagg
    16381 tttaagagtg taggccatat tagaactccg taatttcgaa ggcgccagtt tctttttcgt
    16441 aatcgagcaa tttgtcagac aagagttcga tatattcgat attgtactct gggcgatttt
    16501 cttcgacaag ttggcgagca gtgatacggc cctcaagttc tgagctggca tcgatgtcta
    16561 ggtaaagcgc gcgtgttgtt tcacggcgtg ggctacgttc ttttgtttct tgataaaaaa
    16621 ctttgtaaat catatagttc ctttctattt acaggtcagc ttattccaaa cttttagcag
    16681 agatttgctt gatttcattc cattttgtgt ctagattgac cttgattcgt tacaattatt
    16741 tcaattatac cacaaaatga aaaattagta aaagacggaa acgagaaagt taggggacga
    16801 tttctttggt aagcgtttgc aaaaataaag aaaatgtatt atgttgataa cggaagtgaa
    16861 atttattgct tgtcataatt ccatatagat tttaagtcaa ggaggttgcc ctatgtataa
    16921 cttatttgct tttgctatcg gagttcgttt gctagctttt atcgtttttg ttgcttgcgt
    16981 ttatggagga aatcttctat ttgccaaact ggaacgacga caaaccaagt tcttgtggaa
    17041 aatgaccttt gtgactctct actcgctttt tctcctcctc gtgacctatg tcgtttggtt
    17101 tgtattttac tttgaattaa atgcttagat gccctgctta tgctggggtt ttttgtttgg
    17161 ggatgtagag atagtagatt tacgacacga aaattccacc ccatctatca agatgaggtg
    17221 gtctttgcat ttttctaaca tgacatgaca atggaatttt caaagcttat tatttttatg
    17281 ggagtcattg ttctgatcaa aaatagagtt gaagcataaa aataaaacaa tacaaacaga
    17341 taaatcgaat ggtaaaggga tggtagtaat gttcaaatca ttgagaatgc tgagcaaact
    17401 gtaagagatg aagacaataa aatttatcct tctaaaaatg tgtttcttat ctagcatgac
    17461 ttaccaaact ttttacgaag gtcttttcca atggtataac ctgccataaa taaagcgata
    17521 ccaacaccga caccaaagcc acccttgatt tcttgcaatt ccttattaga aatttcacga
    17581 taattgttca aatctttcat catattaatc tcctcctaaa aaataaccag ctgccaaacc
    17641 agaacctata agtgctgttc cacctgcaat agccttccaa gatactgcta ctccaaagat
    17701 aaccaaggga gcgagaccgc catcaatatc tgataattca ttttcagata aggataaaaa
    17761 ttgattgtca agaatgtcaa aatttgtcat tgaactttcc tccttttttc ttgttcactt
    17821 ttatattcgg aaaagaaaag gaaaagtgag cattttttta aattattttt agttaagtga
    17881 gggcactctt gtctgggggc aaagaaaatt cccatgtgcc agcttttgta gtataatagt
    17941 aagcagacaa aaagatagga atgtgttatg aaagtattag cttttgatac gtccagcaag
    18001 gctctttctc tggctatttt agaggataag caggttcttg ccgagacgac gattaatatt
    18061 aagaaaaatc acagtattac tcttatgcct gccatcgatt ttttgatggc aagtttggat
    18121 tggacaccca aggatttgga ccgaatcgtg gtagctgaag ggccgggtag ctatacaggc
    18181 ttgcgaattg cggtagcaac tgctaagacc ttagcttaca ccctgaacat cgagttggtt
    18241 ggtatgtcga gtctcttggc tctggtgccc caccaacaag aaggtttgtt tgtccccttg
    18301 atggatgcgc gtcgcaataa tgtttatgca ggattttatg aaaatgccaa acctgtcatg
    18361 gcagaagcgc acctatcttt tgaagaggtg ctagaaaaag tcaagggtac tagtcaggta
    18421 acctttgtcg gagaagttgg cccctttgtt gagcagattc aaaaacactt gccaaggact
    18481 gattacaaag aaacattgcc caatgcagcc aatcttgctc ttttagcttg ggacaaggaa
    18541 gcagactcct tgcatgattt tgtgccgaac tacctcaagc gtgtcgaagc tgaggaaaac
    18601 tggctcaaga atcacaccga gtctggtgag tcctacatta aacgcctatg atagaaatca
    18661 agcgaattca acaacatcct gacctagctc aagccatcta cgctgttatg gcagctgttt
    18721 acctagtcag tccttggact ctggagcaaa tccaagcaga tctgtcccaa gaccagactt
    18781 ggtatgcatt ggcttatgat ggggcagaag tgattggatt tctagctgtg caggagaatc
    18841 tttttgaagc agaagtcctg caaatcgctg tcaaaggagc ttatcagggt cagggaattg
    18901 cgtcagcctt gtttgctcaa ttgccgacag acaaggaaat tttcctcgaa gtcagacagt
    18961 caaatcaacg agcgcaagca ttttacaaga aagaaaagat ggcagttatc gctgagcgaa
    19021 aggcctacta ccatgaccca gtcgaggacg ccattatcat gaagagagaa atagatgaag
    19081 gatagatata ttttagcatt tgagacatcc tgtgatgaga ccagtgtcgc cgtcttgaaa
    19141 aacgacgatg agctcttgtc caatgtcatt gctagtcaaa ttgagagtca caaacgtttt
    19201 ggtggcgtag tgcccgaagt agccagtcgt caccatgtcg aggtcattac agcctgtatc
    19261 gaggaggcat tggcagaagc agggattacc gaagaggacg tgacagctgt tgcggttacc
    19321 tacggaccag gcttggtcgg agccttgcta gttggtttgt cagctgccaa ggcctttgct
    19381 tgggctcacg aacttccact gattcctgtt aatcacatgg ctgggcacct catggcagct
    19441 cagagtgtgg agcctttgga gtttcccttg ctagcccttt tagtcagtgg tgggcacaca
    19501 gagttggtct atgtttctga ggctggcgat tacaagattg ttggggagac acgagacgat
    19561 gcagttgggg aggcttatga caaggtcggt cgtgtcatgg gcttgaccta tcctgcaggt
    19621 cgtgagattg acgagctggc tcatcagggg caggatattt atgatttccc ccgtgccatg
    19681 attaaggaag ataatctgga gttctccttc tcaggtttga aatctgcctt tatcaatctt
    19741 catcacaatg ccgagcaaaa gggagaaagc ctgtctacag aagatttgtg tgcttccttc
    19801 caagcagcag ttatggacat tctcatggca aaaaccaaga aggctttgga gaaatatcct
    19861 gttaaaaccc tagttgtggc aggtggtgtg gcagccaata aaggtctcag agaacgccta
    19921 gcagccgaaa tcacagatgt caaggttatc atcccccctc tgcgactctg cggagacaat
    19981 gcaggtatga ttgcctatgc cagcgtcagc gagtggaaca aagaaaactt tgcaaacttg
    20041 gacctcaatg ccaaaccaag tcttgccttt gataccatgg aataaagagt ggctctttgt
    20101 caagtgtagt gggtaggcga aaagctacaa tctggagagt acgaaattcg tactctcttt
    20161 tttgatgttc aaagtcatca aaatccgttt tttaaaattg ttaaagttcc ggaaaccaaa
    20221 ggctttgcgc ttgataacct taatcaaatt attggtcgct tcaagtttag cgttggaata
    20281 aggcagctta agtgcgttga taatcttatc tctatccctt aaaaaagtcc aaaagaccgt
    20341 ttgaaaaagc ggatgaaccg ttggcagttc ttgctcaatc aatccaaaga aatggtcggc
    20401 attcttctct tgaaaatgaa agagcaggag ttgatagagt tcgtagtaaa cctgtaatcc
    20461 ctcagagtaa gaaagcagct tatctcgtac ttcccgatgg gttaagtgca ttcgaaacgt
    20521 gggctgatag aatcgtttct gacagagctt gaagctatcc tggtgtagta aatcagtcca
    20581 gtggactgat ttagcccgag cctagaaacg aaaaagcgag ggttccaaaa gcgcttgagc
    20641 gcccgatact ccaaggattt tcggtcaaat tggttcatga tttggattcg tactcggttc
    20701 atagctcggc tcagatgttg gacaatgtgg aagcggtcaa gaacaatctt cgcctttgga
    20761 aagagttgct tagcgagccg ataataaggg ctgtacatgt ccatggtgat gacctcgacc
    20821 agctcccgaa cctctctctg atagcgttgg aaatggtttc gaatcaccgc atgagttcgc
    20881 ccgtctaaaa ttgcgaggat ggatttggac tcaaaatctt gggcaatgaa gctcattttg
    20941 ctctttttga agctatactc atcccaactc ataacttttg gcaacttggt ccaatcggtt
    21001 tcaaacttaa attccctcag ttttcggatg acggtggaag ttgagaccgc caatctgtgg
    21061 gcaatctcag tcatagactg cttttcaagg aggagctgag cgattttttg tctcaccatg
    21121 ttggaaatct ggcaattttt cttgacaatg gatgtttgag aaacgaccac cttaaggcaa
    21181 ttcttgcact gaaagcggcg ctttttgaga tgcagtaccg tgggtaaacc ctgacagtcg
    21241 agaagcggaa ttttagaggc tttctggaag tcgtatttga tcatcttccc ttgacaatga
    21301 ggacaaggag gagcggggga atccaacttt gcctgaacga ctagatgggt ttggtatttc
    21361 agaacagaca agattttgat atttttgtct tccaatccga gcaaatctgt ggtattctta
    21421 agttgttcca tatgaaccct ttctaatgag ttggttagac gcttttcatt ataggtcata
    21481 tggggctttt tttctacaag aaacgaccct ataattcctg gggtgggatt acccactaca
    21541 gaaattatag agccaaagca ttccaaagtc ttgtctgact ctggaatgtt ttctgttcac
    21601 agttgttttg taactgccta ataagtaacc gcgctataac gaggtatcta ccgagattgt
    21661 caattctcca gtatactgtt ataaaaaaca aaactggagg atttttttat gtccccccat
    21721 cgtcccatcg actgttccgt agctgcccaa taacggagta tagtcggctg aaacaagaat
    21781 aggacaaaag tgcctcaaga aaagcatcgt aatttgacaa tattattctg agatgttttt
    21841 gatgtaagcc catattttct caatgggatt atactcgggt gaataggtag gaagtggtaa
    21901 cagtctatgc cctgctcctt acacatgttc attctgtgaa accttgcatt gtccataatg
    21961 ataagggatg gtgtatctaa agtaggtagt aagaattttt ggaagcaagc ttcgaaggag
    22021 ccatagtata ttgaaacaaa aaagggcatt agtacttcta taacagtatc gcaatctctg
    22081 gtgtgcgttg tctcgatctt aattcaaata attatatctt cttccagaga gactaactgc
    22141 ctgctcaagg ctcgatcata ttcgagataa aaataggtct taacccctgt ctcataaata
    22201 taaataggag tcaggtagct taagtgattc aattctttaa ggaaccgatt tactttttct
    22261 gggtcttgtt cgcagtaggt acggctcttt tttagactat atcccatagc ctttagagcg
    22321 taatgaatag ttgttggagg acagttgaat tcagcagcta tttcagtcaa ataagcatcg
    22381 ggatgagttt caatatagat ctttaattta tctctatcaa ctttttcaat taatagtgga
    22441 agttttcttg aagttagtgt attgaaacgt ttttatacag tgctaaaatt tgaagtgtag
    22501 tgcagatgta tttgtaatag tattatagca attctttgga gaaggtcgag acaagagaaa
    22561 ataggtatct ttgagatata agcatgattt actataaaat tattgagtta ttcataaaaa
    22621 tttctctatc aaatatcata atgcgtcgtt taaggagatg gttacaatgc aatatagttg
    22681 tggaaaaata aatattaata tccctgatgg atatggagac attaaggata tagtgttttc
    22741 ggctcatatt atagttaggt ataataatgg acattgtgga ggtatagatc cgcatataat
    22801 tggactttgt aaaaagcaga tcagaaggat gtctctatat cctattttga taatcgtatc
    22861 tagagattca aaggttattg atgattataa aaatttagat attgcctatg ttgattgtac
    22921 tcaatgttca aataattttg aaactgcctt acacgttaaa aatattttaa aattattaaa
    22981 aa
//
LOCUS       DAVKMJ010000036        21391 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000036 DAVKMJ010000000
VERSION     DAVKMJ010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21391
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.036"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(436..2163)
                     /gene="ezrA"
                     /locus_tag="VW348_001547"
     CDS             complement(436..2163)
                     /gene="ezrA"
                     /locus_tag="VW348_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEU9746427.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPPQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2245..4191)
                     /gene="gyrB"
                     /locus_tag="VW348_001548"
     CDS             complement(2245..4191)
                     /gene="gyrB"
                     /locus_tag="VW348_001548"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEU9746428.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVYVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4206..4769)
                     /locus_tag="VW348_001549"
     CDS             complement(4206..4769)
                     /locus_tag="VW348_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEU9746429.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4854..5408)
                     /locus_tag="VW348_001550"
     CDS             complement(4854..5408)
                     /locus_tag="VW348_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEU9746430.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYQDVFGKNQ"
     gene            complement(5419..6642)
                     /locus_tag="VW348_001551"
     CDS             complement(5419..6642)
                     /locus_tag="VW348_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEU9746431.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6679..9129)
                     /locus_tag="VW348_001552"
     CDS             complement(6679..9129)
                     /locus_tag="VW348_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEU9746432.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVVLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9329..10258)
                     /locus_tag="VW348_001553"
     CDS             complement(9329..10258)
                     /locus_tag="VW348_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU9746433.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10398..10685
                     /locus_tag="VW348_001554"
     CDS             10398..10685
                     /locus_tag="VW348_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEU9746434.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10719..12053)
                     /gene="ciaH"
                     /locus_tag="VW348_001555"
     CDS             complement(10719..12053)
                     /gene="ciaH"
                     /locus_tag="VW348_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEU9746435.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12043..12717)
                     /gene="ciaR"
                     /locus_tag="VW348_001556"
     CDS             complement(12043..12717)
                     /gene="ciaR"
                     /locus_tag="VW348_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEU9746436.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12826..15372)
                     /locus_tag="VW348_001557"
     CDS             complement(12826..15372)
                     /locus_tag="VW348_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEU9746437.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15495..15935)
                     /locus_tag="VW348_001558"
     CDS             complement(15495..15935)
                     /locus_tag="VW348_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEU9746438.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQAHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15910..16779)
                     /locus_tag="VW348_001559"
     CDS             complement(15910..16779)
                     /locus_tag="VW348_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEU9746439.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPSVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16821..17549)
                     /locus_tag="VW348_001560"
     CDS             complement(16821..17549)
                     /locus_tag="VW348_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9746440.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17557..18036)
                     /locus_tag="VW348_001561"
     CDS             complement(17557..18036)
                     /locus_tag="VW348_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEU9746441.1"
                     /translation="MEIKNHFGVYCVCFENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVIALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGLPELDKTSYMNWKVK"
     gene            complement(18047..18745)
                     /locus_tag="VW348_001562"
     CDS             complement(18047..18745)
                     /locus_tag="VW348_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEU9746442.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFETGGLADWVASETPIKRWIEPEEVAEVSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18738..19004)
                     /locus_tag="VW348_001563"
     CDS             complement(18738..19004)
                     /locus_tag="VW348_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEU9746443.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(19070..19996)
                     /locus_tag="VW348_001564"
     CDS             complement(19070..19996)
                     /locus_tag="VW348_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEU9746444.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20071..20886)
                     /locus_tag="VW348_001565"
                     /pseudo
     CDS             complement(20071..20886)
                     /locus_tag="VW348_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(20890..21210)
                     /locus_tag="VW348_001566"
     CDS             complement(20890..21210)
                     /locus_tag="VW348_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEU9746445.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6477 a         4691 c         3744 g         6479 t
ORIGIN      
        1 aacaaaaatg ttttagaggc ctatttaccg tggactaaag ttgtacaaga aaaatgcaaa
       61 taagaaatct ccagattagg aactatccgt gagttctcta gtctggagat ttttcaatag
      121 acttcgttat tggacggtta ccaagttact caaagtacag atttgaagct gcagataaga
      181 ctgacgaaat cactttaata ctaaatgaaa atcaaaaagc aaactaagaa gctagcctca
      241 ggctgtactt gagtacggta aggcgacgct gacgtgattt gaagagattt tcgaagagta
      301 taaaacactg ttttgaggtg gtggataaat cggctgggta aaaactcaat ctcaggagaa
      361 aatgaagtaa atctccccac aactatagaa aaagatttga ttctgctcct cacacaataa
      421 aatctttttc ttttattaaa aacgaatcgt ttcacgtgtt ttctcatatg aggtaacaaa
      481 gcgattggtt acaccaggct ctgccacttc caatgcttga gaaatcttat caaatgaagc
      541 gtgataatca aattcttttt caaaaatatc taaagcttcg ttaaatgctt cttgaatgcg
      601 ttcatcaaat gagcgatagc ggttagaata ttgcaagagt tgctctgtca aagttgcata
      661 ttgtacaata ttataagttt ccgtttctaa agcttccata tcattcgttg caatttcaag
      721 aactcgggta acagattcaa tgttaatcat tttttgttct aactcaacca ttaaatcctc
      781 ggtattattg cttgccgtaa agaataactt caagaaagtt tgtggaatac ctggcagatt
      841 gcgtttttcc atgtatcgct tgatagtatg gagacgattg acataaacat tggccttttg
      901 acgtgcatta atatcatctt tctcaatttg tgtcaggcgc tcactaactg aaatttgctc
      961 atcttcaata tcttttagtt gagtttgtaa atcctcaaga ttttcttcaa gaactgaata
     1021 agcttggggt ggttcttctt gatttgaagt tacctcaaca atagctgcct caaaactctc
     1081 taattctgtc tgaatacgac gaacatggct tgcagctgtc tcaggaagta aataggtctt
     1141 gttcaaacgt gcaatatctt ctcccaataa agtattattc tctttcatat gttgaagata
     1201 agttggaaga gttgcaagta gattttccac tactttctga gcagcaattt ctcgagtaaa
     1261 aatatcatac aaggcattga tttcctcttg tgcctgtcca ttctcatatt cggcattatc
     1321 caattccaac tgacgaatat tctcttggtt tttcttgaat gcttcataaa gcaagtggaa
     1381 acgcgcttca atatccgttt caacaaaatg ataattagca tcaattagtt tacgataacc
     1441 ggcttccaaa tcctgtaatt gatctggcaa ttctgtagaa agcgtcgtaa ccaaggctgg
     1501 aacacgatcc acaatatgac ttaaggccaa aatgtgattt tctgtattat ccaaaatcac
     1561 tgcggcttcc acagggtcac ccgatgaatt caaggttaca aattgtgaaa attcagattg
     1621 gatattttct aattgttttt caatttcatc caaggcttga ccatactgtt ctgaattttc
     1681 agcaactcta tgctgaagtt cctcaaataa atccaaagca tgaagaacac gaccactatt
     1741 tttagattct tgcttctcta agtctgccaa agcattgcga attgccgcaa tatcttcttc
     1801 aatcaaagta atttgactct caatttggtc aatttgatga ctggccttga gaaaacgaaa
     1861 tgaatggtta taaccttctg cttcaaagag attattttca atatcggcaa aagagttgag
     1921 agataaatcg acccattttt gattccattc acggaaagcc acttgacttt gtccaatcaa
     1981 gtgcatattt tttacagctt ctacttcatc atttactgga agattgtata gttcttcttt
     2041 tctttcttct agtgcctcta atctcccctc gtttcgctta cgtagaaaga ttgccactac
     2101 ataagccaga actaaaatga ctgcaattgc aaccattaaa taaattagtt gtccattaga
     2161 catatcaaac tcctttttta cttgaaacaa tcgtaacgat tatatcatat tttttagacc
     2221 aagggaacta cttctcccta ttttttagac atcaagtgta ctatagacag cattttcttc
     2281 gataaactca cgacgaggct ctactcgatc ccccatcaac atatcaaaga ttttatctgc
     2341 ttctgcagca tcatctacag aaactctagc catcaagcga tgttcgggat ccatggttgt
     2401 ttcccacagc tgatgatcgt ccatttcacc tagcccctta taacgctgaa tagtcggttt
     2461 ggtacgacct tcactataac gggctaaagc ttcttggagt ttgatttctt gatctgcacc
     2521 cggctggata tattctttaa tctcgcttcc aaccttgaca ccatagattg gtggttgggc
     2581 aatataaaca taaccagctt ctaggattgg tttcatataa cgataaatca aggttaaaag
     2641 aagggtacga atatgggctc catcgacatc ggcatcggtc atcaaaacga gtttttggta
     2701 acgggctttc gaaacatcaa attctgcgcc aaatcctgtt cccatggctg tgaaaagact
     2761 acgaatttct tcgttagcta gaatcttatc catacttgct ttttcaacgt tcaaaatctt
     2821 accgcgaatt ggaaggatag cctgaaactc acggttacga ccagatttgg ctgatccacc
     2881 agctgagtct ccttcgacga tgaagagttc tgtttcagca gggttattag aagaacagtc
     2941 tgctagtttc cctggaaggt tggaaatttc caaaccagat tttttacgtg tgacttcacg
     3001 cgcacgcttg gcagccacac gagccttggc agctaaaatc cctttttcca cgatacgttt
     3061 ggcaatctgt ggattttcca tgaggaaatc ggagaaggct tcactgaaga ggcgattggt
     3121 aatcttgacc acttcgctat ttcccaattt ggtcttggtt tgtccttcaa actgtggatt
     3181 tgggtgttta actgagataa ctgcagttaa tccttcgcga acatcttccc ctgttaaatt
     3241 atcttcattg tctttcagta acttattctt acgagcataa tcattgataa cacgagtcag
     3301 tgccgtacgg aaaccttgtt catgcgttcc accttcatgg gtatgaatat tattggcgaa
     3361 actcatgaca ttttcatggt aacctgttgt gtactgcatg gctacttcaa ctgtaatatc
     3421 atccatctca ccgtctgtat agattggtgt atcaaagatt acatccttgt tctcgttgat
     3481 atattcaacg taactagcaa tcccaccttc ataatgataa tgcttggttt gttccaaacc
     3541 ttggcgctta tcagtgatgg aaatttgaag accgcgattt agaaaggcca actcttgaat
     3601 ccgtttattt aatttatcaa aatcaaagat tgttgtttca gtgaaaattt ctgggtccgg
     3661 tgtgaagtga accgttgttc cagttctatc tgtatcccca accacctcaa ggtctgcaac
     3721 aacatgacca cgacggtatt cttggtaatg aatcttaccg tttttatgga cataaacgtc
     3781 taattgagtg gaaagggcat taactactga cgaccccacc ccgtgaagac cacctgaaac
     3841 cttgtatcca ccaccgccga actttcctcc agcatgaagg actgtaaaga cggtctcaac
     3901 agcaggacgg cctgtttttt cctgaatatc gactgggata ccacgcccat catccacaac
     3961 agtaatcgaa tcatctggct caataaaaac ttgaatatgg ctggcaaatc ctgccaaggc
     4021 ctcgtcaatt gagttatcaa caatttccca gactagatgg tgaagacctt cttttgaggt
     4081 tgatccaatg tacatccctg gacgcatacg aacagcctct aagccctcta aaacttgaat
     4141 ttgactggca tcataatcct gtgcctgcag atttttgatt tcttctgtca tcttattcct
     4201 ttttcttata tgtctaatac ttgtcttaaa ttcacgatac tggtaaacaa gtgggtatca
     4261 agtcctgcag cttgacctgc ttcgatatca atcggccgat caccaatgac aagaccagag
     4321 ctaatctgat acttttctct taaataaagc atggattcgg gatttggctt tctcttaaag
     4381 cctgagctag aagtcaccac ttctgtaaaa taagctgcta tagaggtttt ttctaaaatt
     4441 tccaaaacct gatcatttcg atgagagacc aaaaaatgac ggccaccttg atttgaaatg
     4501 acttccaata ggtcagaaac tccttcaaat aaaatcgggt gttcaagctc tctggcttca
     4561 ttttccttgt acttttctaa aaaattctct aaattgggag cgaatgtctc aatcgcaaaa
     4621 ggagtagaaa cctttaaagc ttgatagaca ctgtcatggt cttgtgtgat accatacagt
     4681 gccaatgttt caacaaatgc agctgttgaa gtttcataat tatccagtaa agttccacct
     4741 aaatcccaga tgtaatcgtg atatttcatg ccctttatta tagcattttt ttatgaaaaa
     4801 agcgatgatt tccctgagtt ttccacataa aaaacgagag aataactccc gttttactga
     4861 tttttaccaa agacatcttg atagagcatt cctgttcgta aactctctgc gtcccctcct
     4921 agttgctcca ccaactcgta ggcaaaggca agggctgttg aaggaccccg actggttgtc
     4981 aactgaccat ctaccactac tgtttccttg acgtagtgac catcaaggat ttgctcttga
     5041 acgccgtcat aacaagtgta tcgcttattt ttcaatatct ctgcttgatt gagggcaatt
     5101 ggtgccgcac aaatggctgc tagtttcttc ccttcttgct cgaagctttg caattcttga
     5161 atcaaggtct gattatcacg taaatgtgca gaaccaggca tacctccagg aagaacaatc
     5221 atatcatagt ctgataaatc tccatcaaag acatgatctg ctcttacttg gattgcatgc
     5281 gaacccgtta cttgctcttc aaaaccaacc atatcacatg tgatattggc tcgacgcaag
     5341 acatctacaa ctgtcaaggc ttcaatttct tcaaagccct gagctaacat aactgctact
     5401 tttaccatga ttttctcctt atttaatttg ttttaataca acctttttcc gtttgaatgg
     5461 gacttttccg ctcttttctt cagctaaatt agtctggtaa ctcatcgata aaagcaaacc
     5521 aacaccaatc aaattactga taatagctga tcccccttgc gaaatgaaag gcaagggaat
     5581 ccccgtcaaa ggaagtagtc cagtcacagc accgatattc tcaaagatgt ggaagagcaa
     5641 catcataatc aaacctgtgg aaatataagt gtagaactgg ttatttgatt taagagtaat
     5701 cttcaacata cggtaaatca acatgagata gagggcaata accaggacag agccaataaa
     5761 gccaaaatct tctgcaataa ccgtaaaaat catatctgac tctcgaactg ggataagcag
     5821 attcgaagca ttaaatccct gaccaaataa gccaccactc ccaatggcaa tctgcccttg
     5881 agcctgctgg taagtcgttg tttgggcaaa ctcaaaggga ttgagccaag ccaaaatccg
     5941 attaatttgg taggtcggca ttccaatctg gtgaagaaaa gctcgtccgt ccttgctaat
     6001 aaagatagct aagaaaccag caactcctgt tacagcagtc acaaatactg ggataataat
     6061 tttccaagaa acccctgata ataaaacgat tcctgagaaa atggctacaa aaaccaaagc
     6121 cgtccccaag tcactttgaa gtgctaaaag aactaggact ggaatggtaa agagaatcat
     6181 ccagaaaatt aacaaaaagt ccagcggaac cgtgcgtctc cattccttat gtttctttgt
     6241 aaattggaca atgacacgag ccaacatgag gatataggat atcttcataa attctgacgg
     6301 ttggaatagg gtaattccat ttattgatac ccagtttttg gcacccgttg atgcaactaa
     6361 gcttggatta taaaatacaa tcggcaagat cataagtccc aagcctaaaa tatatagaaa
     6421 gggggtcacc ttccaaagaa attctgtatt aaagagcatg accacaaaac caatcacaag
     6481 ccccaaggca atccaggcga cctgctgccc taaaatgggc agaatattat tgggataatc
     6541 atgactaacg gctatataga tagccaccac accgatgacc agtagaaaaa atactggcaa
     6601 gagcaaactg taatcgactc ttgagtcgag agaacgtttc atatatacta accttatact
     6661 ttcatacaat actatttatc aaagttcatt aaaaaatcta tcaatagcct cgtcaacttc
     6721 ggatcgagag atggttttaa cagtcgcttc ttctgctaga gatgctacta tttgtttgcc
     6781 gtatcgtttt ccgacgattc tcctatccaa aataagagtt aaggaacgtt ggtattcacg
     6841 tctcatactt cttcccaaag cctgttttaa acgaataatg gccattggca attgataatc
     6901 ataaaaggca tttttccctt cttgattcag ttcttgatta atctttttcg tcaagggttc
     6961 ttgaggattt tggaaaggaa gcctcggtac aacttgaatc acaaaaggat ggcttgaaaa
     7021 atcaactccc tcccagaaac ttgctgcacc aagcaagatt tgttgttcac ctttttcaaa
     7081 gcgtttcttt agctgatgaa catccccatt tttatactgg gccaagtggc taactgtaag
     7141 taaatccgat actgctagaa gcatgtcttt agcggtaaag agaaccaaaa tcggttgctg
     7201 gaaagcttga atttccacta gtaaagcagc tacctctctg gcatagactt ctaaggaggt
     7261 ttctgttacc agagggaaat ctttgaccat aaccacttct tgttcctgtt ttccccgaga
     7321 ttcaatcttg acaaatttgg cttcaggata gcctaaaagg tctgccaaag aaaccctctg
     7381 actaatctca agagtagccg atactcccaa gacttggcaa ctctcaggaa gtaaagagga
     7441 cagaagagta cggcctgatt ttgtagaaga aatctgaatt ttcttttgac tcgtttcagt
     7501 tacttcaagc cagtaatcac cttcagctgt aaaatagcga accagctcat caaagccttc
     7561 tacttctaat tctgaaaaat actgatggag attgtccaga gaatctaaga tatttttcct
     7621 agatttacca gactgaaatt gttctatcaa gtagagacac tcaaagcgaa tactttctag
     7681 tatccgttgt tgaaccctgt tttcttctcc tactaaagcc ttatcaatta aatcgataat
     7741 agattgtata tcgtaggtct cttgaagcag attttctaga gctaacaaaa tcttttggac
     7801 ttcatcaata atcagtaaac ggtcactgac aaattcagga ttatcttcaa gtctggtcac
     7861 gagataggca tgattagtca ctaaaagctt gcaagtctct gccctttctt gactacgttt
     7921 ccaaaaatct tccgtcacaa ataagctctg ggatgataaa ttcccatcat gacgaaggtc
     7981 tgctagaaaa tgttggtaac ggtagagttg cccgatttca tccaaatctc ctgtctctgt
     8041 ctcagtaagc cagaccaaga cttgcatttt aaagcgtcta aataagcgat tttcatcatt
     8101 ttcctgcaag gaatgataaa aggcatccaa cttcagataa ttttgtggtc cctttaagct
     8161 atgaatatct gtatggaaca cttccttgag acgtttacct tcttcttcca tgatttgatt
     8221 ttgaagaatc tttgtcggaa cactaagaac aatttgtcgc tctttggatt gagataaagc
     8281 gggtaagaga tagccatagg ttttcccaat ccctgtcggc gcttgaatca gagagacagg
     8341 ttcatctttc aatagcaaga caacctcttt agcaaaactt tcttgttcct ccctcacttc
     8401 aaggttcaac agagaaatat ttttagaaaa gtcttgagat agttttcgta gctccagaga
     8461 agctgccgtt ttcttaaaat acagaccttg aacttggacc aagtctggag aactcaggat
     8521 agattggttg cgataagttt cctcaataac caggtaggac tcatatagga gagcgtcagc
     8581 catttccagc aagcgttcca agagaccttt aggaagctgg gtcatctttt cccgtaaaaa
     8641 aagaagtaat tctgctgtag cttgggcatc tgaaagggct gtgtgtgcgt gtttaagagg
     8701 aattcctaat tctcgacaca aaatcggcaa gctatatttt tccagttcag ggaaaaagac
     8761 ctgggccaat tcgaccgtat caacacgagg gtttcttagc tcatagcctt caaaaaataa
     8821 attttccgcc aagagattag catcaaactg aacattatgg gctacaaaaa tcccatcctc
     8881 caccaagtca aatatttttc tggcaacttg cgaaaaatca ggtgcttgcg ccagacgttg
     8941 gtctgtcaat cctgtcagtt ctttgatatg agcatccaag ggttcatgtg gattgacatc
     9001 cgtcgtatag tgatcgacga tttctccgtc ctcaatcacg acaattccca cttggataat
     9061 tttagcctta ctacctgtgc tagttgcctc taaatccacc acaacatagc gattaccaat
     9121 cgttttcatt ataaaaaatt ataccaaaaa aagggctatt tggcacctgc aaacatagga
     9181 taattttcaa actcaagaac actacttttc ttaaaaatcc catcgaatag agcattctag
     9241 cctgctgatt tttgtaaaat agtgaagaaa tacgaaaaat tgagagaaga aatgttttca
     9301 tcttccttct ctcaacgaat catgtatttt atttaaccat gtcaggatcg tagtcataaa
     9361 atcctgtatc aaggaaacgg tttttagggt gaagtttacg aacttcttca tccagcaaga
     9421 aggcttgatc atggctaaag ttgccctctt gaatcaagtt acgcgcttgg ataaagagtt
     9481 ttgcaatctc aacaaagttc tgaccaggag tgtagagccc ttctagtttc cagcgagtaa
     9541 agccatgctc caccaattct gttaatttga tcatcaaatc aaggtcattg ttggcaaaga
     9601 tatgggtccc atgattatct tcaaaaatgg aatagtggct ctctggatca cttggctcag
     9661 ccaagaagag gtcacgttta tgcgtctttt catcatcgat atgtgtaaag ttatagtagt
     9721 tttgcaagag tggacgttta gaatgatgga tgacgctagc accgtaaacc aaaacttcag
     9781 caggaatttc caaaatctct ggcattttga aaagttcagc tgatggaatt tcacgcgcca
     9841 aaacagcctc agatgcacca gccttttgtc cccagaagtt aatctgacga ctgctagtta
     9901 ccatggttga agcatcgtag atggtcttaa atgaataacc atcgcggtta actacgtaaa
     9961 agacgcctgc atccccaatc gtaatatagt ctgtcttgat ttcttccaag aagtctaaga
    10021 aaggcttgat acggtccatc atatcttggt gcatgagagc attgaccgca acgagcaatt
    10081 ccttaccagc atcatgaacc aacttagcga tttcacgtaa ttggtcataa ctaaaggtcg
    10141 ttggcagacg aaggccaaaa tctttctcac cgacatagat acggtctacg ccagcttcga
    10201 gtagttgttc aacttgttca atactttcag cagttgctgt aatgacaatc ttttccataa
    10261 gaaaaattat accacatttc tccaaaatca gccatgcttt gaaaatgaaa agggacttta
    10321 ttctttttgt aacctttctg taataattct ctgccgaaaa aatgataaaa taggtatgta
    10381 ctgttaagga gagaatcatg cccgtaagaa aattacaatc ctatgaggta gactatcaag
    10441 aagaattaaa ccagcagctt cctcattacc aagcttatac acctgaagcg caatctgatg
    10501 ccaatctcaa ggaaatccta ttttttatta atatcgctgt tttttgtatc tgtattgcta
    10561 tctttagttt tatcttttta gcattaaaat tatcaactgc tcttgccttt gccgcagcaa
    10621 tcggattcag cttacttgtt ttaaaagttc aacggtctat tatcaaacga aaacgtagaa
    10681 gataaatcca aaatatcgcc ccaattggag cgatattttt attttttctt tttagatggt
    10741 gtctgaatgg caatcttcac ttcaaagatt gttcccttgg gtttattatc tttgacagta
    10801 acagttcctt ttagagcatc tacaatttgc ttggctaggg ataatcctaa accaaaacca
    10861 cctttttgcc gggttctagc cttgtctact cgataaaaac ggtcaaaaat tttcttttta
    10921 tcttctgtcg aaataccgat tccattatca gaaacaagta aataaagatt gcgatcggtc
    10981 gccgagataa gaaaatcaat ttcaccatcc tcctcagtat acttgacggc attatcgaaa
    11041 agaatggtca tcagttgttt cagaagaagc tgatctgtga caattgttcg atggatacga
    11101 ttttcaaaac ggaagacacg attattttcc gaagcaatca tctcatagtt tgtgaaagtt
    11161 gtattaaaaa agctagttgg aacttctgca agctccggct taatcccatc atctctccga
    11221 gctaagttca gcaagcttgt cgttaaaaaa cgcatatttc ggacttcttc caaactcgat
    11281 gcaatgcttt cgctcacatc cataatggta gcttctggct tacgaaaaag ggtctctaag
    11341 cgattttgca aaactgcgag tggagttcgt aactcatgac tggcattttc cacaaaagac
    11401 tgttgcttct gcatactctc aagcaagggc ctaacactga ccctagctag atagagactg
    11461 gcaagtaaag acaaaatcca gaaactagcc atcacgacca caatcaattg ctcatgcttt
    11521 tgactagcct gctccaactg actggtatta atcaagacag cagcatactt gatattggtt
    11581 gaaaccgaac taatattggt ctccatcaaa atcacacgat agatttcttc ctgcccatag
    11641 ctattaaaaa cctgaatctg gtagatatgt cctagttctt tcttttctaa cttaatctta
    11701 tccaagccca aaaatcgatt tccagaaaga agttgagtaa agtctttatc aaagagaatg
    11761 acttccgtat tggaactgac attaggtttt atttctactt tactagcgtc cgccctagca
    11821 ttttctaaat ctttaatctc ttctgttgcc ctatttatag ccagctgaat aactgcttga
    11881 ggattttcac tcagtccatg aagcttatcg tccaccgaag tataaagact cgaatgcatg
    11941 acttgtaaaa taatcagagt cattgtagaa aaaatcaggg tgaagacacc gaagttgcgg
    12001 ataaaataac taaagtcatc cgcataccat gtttttttaa gtttactgaa catcttttaa
    12061 aagataccca acactacgca aggtttgcaa attctctgca aaagtggttc cctttaattt
    12121 cttacggact tttgaaacat agacttcgac aaccgaaatc gttgtatcac tatcaaatcc
    12181 ccatagacgg tcaaaaatct gcgtcttagg caaaatcaca ttttgatttt gaaggaaata
    12241 aactagtaaa tcgaactctt tccccagcaa ttcgacagga gtatcttcaa ctttaacggt
    12301 attggttgat aaattaacca cgatattccc ataagtcaag gtgttttcat taaacttccc
    12361 tgaacgtttg agaagggcct gaatccgcat tttaagttct tctaggtaga aaggtttggt
    12421 cagataatca tccgctccca gttcaaatcc atgtcccttg tcatccaaac tttccttggc
    12481 agtcataatc agaactggtg tcgtaattcc cttttcacgc aattctttta agacttggaa
    12541 accatttttt tctggcaaca tcaaatccag caaaatcaag tcatagacac cactctcagc
    12601 ttcgtagaga ccttcttctc catcaaatac ctgcataaca tccgcaaaat cgtctaaaaa
    12661 gtcaaatact gaatttgaca gacctaggtc atcctcaacc aataagattt ttatcatgag
    12721 aaactcctcc ttattaaaac tattatacca aatttgcctt aaaaaaaact caactctctg
    12781 cattttacat gagatagctg agttttcttt ttattttagg cttatttatg catttccgta
    12841 ttgaagaaca actgcttcga ctgcagcttt ttcacggcta atcaagtcaa cacgtgctgc
    12901 aatttccttg attcccatac cgatgttacg gctaagagca aggtcagaaa gttgcggctc
    12961 aaagaactcc ttgtattccg ccaagcgttg ctgagtctta aatacatgag caggaaggat
    13021 aacaaagcta tcaaagctca tatctcctcc aagggctgcc ttaatccaag cccagttttc
    13081 acgcgcccaa gaccaagctg ttttctgagt tgcttgatga gctaggaatt ggtaatacca
    13141 agcagacaag tcctgtggtt tgaccacaaa tttgtccttc caagaagtaa tcaagttttg
    13201 gatattatcc gcatctgtac tgtatgcaag agctgctgcc aactggcgtt taaagacagc
    13261 atctgttgcg tgagtataag tatcaagata aagtgctaac aagtctttag tctcatgatg
    13321 tttcatctca ttaatcagaa cttgtgaacg aatagctgct gggagtcctg caagattctc
    13381 cttgtgtgtt gcgaagattt ggctagcgac ttgactagct tctgcatcat ttgagcgaat
    13441 catcatcgaa acagccagct gacgaaccaa ttcatcctca tctgattctc cgtctttagc
    13501 ttcaaaacca agacggtcat agttatgacg agccaattta gcaaccagtc ctttgaaggc
    13561 tgtttcagca tccgttcctt catcaataaa gcgctcaagg gctgaaatca cttgagaaac
    13621 agctgaaacc accagataag actcttcctt agcaagttta tcaagaactg gaagcaagtc
    13681 tgcataagaa atgtgccctg cctcagccaa caaacgacgt tcttgaacaa tttgcagttt
    13741 gcttgtgtta tcaagtgtct ctagctcagc aagaacagct tctaacaagt ctccttgata
    13801 gtcggtaata tagtgggcag tattttcagt gttgagacga agagctcctt cattttcagc
    13861 aagaagagct gcgtagccag ggatttcgat actttcagtt tcgagtgtat caggcaagcc
    13921 tttccagttg ctattgaggg gcaccaccca gagacggttc ttgtcttcgt tctcaccgat
    13981 gaagaattgt ttttgtgaaa tcttcaagac atcattttca actttaacag taagaactgg
    14041 gtaaccaggc tgttccaacc aagaatccat gaaggctgcg acatcacgtc ctgacgcttg
    14101 accaagggca tcccaaaggt cactaccaat ggtgttgctg tattggtgtt tttcaaagta
    14161 ggcgtgcaaa cctttagcaa aatcagcatc tcctagccaa cggcgaagca tgtgcatgag
    14221 acggcttcct ttggcataga cgatagcgcc gtcaaagagt gtattgattt catctggatg
    14281 tttaacttcg acgtggacag actgaacgcc atcagtagcg tcacgttcaa gagcaagagg
    14341 tactccacct gtttggaaat cttcaaagat attccagctt ggttcgatgg tatccacaca
    14401 gacgtattcc atcatattag caaaactttc attgagccaa aggtcatccc accatttcat
    14461 agtcacgagg ttcccaaacc attggtgagc caattcatgg gccacaacaa gggcaacttg
    14521 ttgacggcta gcaaatgtag agttctcatc gacaaccaag taaacttcac ggtaggtcac
    14581 aagaccccag ttttccatag caccagctga gaagtcagga agggcgatgt ggagagattg
    14641 aggaattggg tacttaactc catagtaatc ttcgtaaaac tcgatagagc gaacagcgat
    14701 atccagtgag aaatcaagat ttgaaagtgg atgtgctttg gttgagtaga cacctaccag
    14761 ggtaccattt ttagttttag cggtcacccc ttgcaaatca ccagcaacaa aggccaacaa
    14821 gtaagaagac atgcgaggtg ttgtctcaaa cttccagata cctgtttcct tacggttttc
    14881 aacatcgatt tctggcatgt ttgacaaggc caattcacct tctgcttggt caaagcgaag
    14941 agagagatca aaagttgctt tggcttcagg ctcatccaca catgggaaag cttcgcgcgc
    15001 aaaatggctc tcgaactgag tagacaagac ctccttcttg actccatcaa ctgtataata
    15061 agaagggtaa atccctgtca tgttgtctgt aattttacca gaaaaggcaa gaaccaattc
    15121 aacttgacca gcctcagcca attcgatatg aagggcttca ttgtcatggt caactgtaaa
    15181 tggacgagct tgacctgcaa cttctacaga ggtgatttcc aagtcttttt ggtggaggga
    15241 gatgcggtca ctctgtgctt gaccagtgat ggtcactttc ccagaaaaag tcttggtctc
    15301 acgactcaaa tctaaaaata aatcataatg ttcaggaaca aattgcttaa taaaatgttc
    15361 aactgcttgc atagttttct cctattctaa gtttaagagc tgctgctctt cttcaaacaa
    15421 acttattata tcatattttg cttgagaaaa aaggattgga cagcgatttc caaaactttc
    15481 ttccttctaa tagtctacag tgggtagacc ttgcgaaatt cttctaaaac aaccttgctt
    15541 tcaggtgtaa aagtcagccc tacttcaccc aaacagtctg tgaaaaagtc ctcatgagcc
    15601 tggcgccaat aggcaagtga tttgtctccc tcaccttcct taaaggcatg ttgcgcagag
    15661 acttgattga agagttcaac agaaaccttt gtaatttcga caatgcagac agactgattt
    15721 tgactatcta aaatgacatc gaaggtccct acttggggaa gtggttcgtc ttctagtaca
    15781 tagaggtcat aggctgatgc tgttgctgtc ttttctcctt taaacaccaa atccgctaaa
    15841 aggtctggtt caactccaaa agcccaagca tcgatttcat ctccgatcaa aggattgatt
    15901 tgcttgtatt tattccacat ttcttgcggt atcatgggta ctcctttgta attttttact
    15961 ttcttctttt atgtgtttaa gatgatctgg atggtcaatc tctaaatcaa aaatctctgg
    16021 aatagaactg tagtggataa tgcacttgat acccaactga ttcatttttt gtatgaaaga
    16081 agtattcaga tagcctgcta cagcaaaatt aatcttgttc tttcttgctt tatcctgcat
    16141 atctcttagc atatctaaca ttattggact ttccatatca tgccattgac tgtttctcat
    16201 agtcgcaaaa acaaaggaag tcaaatcatt cattccaact acaatctttg aaatgcccgt
    16261 ttccagtata ctagataagt caaaatacgc tgacggtaat tcaatcatcg ttccgacttt
    16321 cccagtaaag ccatactgac gcaatactgt aatagcttgt tttaattggt cggcatcatt
    16381 gacagaagga aagataagag atagattggg gttggtttga taaacttctg taacgacatg
    16441 tgcttcagcc tgaaattcat ccaaacacgc cagtaaacgt ctggttcctc tatagccaaa
    16501 caagggatgc ccttcgtcaa aaaactctct agtccccact aaacaattgg cttctgtatt
    16561 cgttaattca gaaaaacgat accaaacttc ttcatctgag tacagggagc agatagtctc
    16621 tagataatct tttacaaatt gctgacaact tgctaatatg atgttttgat taagctctct
    16681 caacaaatat tccccacgaa tcatgccgac gtggtgaaat agttgaggat aaattttttc
    16741 aagaattttt tcgccactaa gggcaagttg atttctcata gccattcacc tcgtcttaaa
    16801 agatacaata tcatatataa ttatatcaaa atttcctcta gttcaaaagc ttcataaggt
    16861 tcagataact catatcctaa aaattctgct acttttttgg aagcctcatt atgagcatcc
    16921 caaagtggaa acatatctct atttaaactc tctagaatca ttgcagcacc aagcttttta
    16981 gcaaatccat ttccttgttc gtttggtcta gttgcaactt ccacttcaac tgctttacgg
    17041 taaactaacc ctgaggaaat cccagcaatc agttcattat ttttaagaat cacaaagcca
    17101 aatccacctt ttaaaacaaa atcctgatag gactcaaaat ccccctgtaa atcctgtgac
    17161 cattcttccg tagaaaagca gttataaata tgattatcaa taggcacaat attgtaacct
    17221 tcctctaaat gagtaactag attatttaaa aattcaactt gaaaatttgc cttatcttta
    17281 aaagaatagc gagtaaaaga atttagcccc acttttcgat gcagaaaatc ttgccaatta
    17341 gtattttctg aaataataat cttataatct aaaccatatt ttctaacaaa atcttcccaa
    17401 aatctggaat ccaactcccc tgctaggtat agaaaattcc caacatcata aaagcttgtt
    17461 gtcctatcat tgtttcggta gacagttcca atttgagatt taagaccata gagaaccata
    17521 tttttcttcc atgttttaaa tagttccatt atccctctac ttcaccttcc aattcatgta
    17581 agaagtcttg tccagttctg gcaatcctaa taattcagac ttaaccttca agactaatgg
    17641 cgatgcattt tcttctgtaa tctcttgaat atccatccaa atatatccaa gtgaatcatt
    17701 cgcaccatca gacacagctt ccgaaatcgt aacttgaggt gcactctcat tcatttcaac
    17761 atcatacaag gctatgacat ggtgaaccat aaaatttttt aactcttccc tgacgaaaac
    17821 atcgtagatt cgaggattag agtagcttct aacagtaaat cccgtctctt ccataacttc
    17881 tctagtcagc gtttccgtca gtccttcacc aagttgctga ctgcctccag gtagatcata
    17941 ccgatgttga taagggcctc tcgttttttc aatgcaaagt aactttccat tttcaaagca
    18001 aacacagtag accccaaagt gatttttgat ttccatccaa ctcctcctac ttcaaagacc
    18061 agccaccatc tattgtcaga atttgtccct gcatggcaga tgcctttcca ctggccaaaa
    18121 agagactgac ttctgccact tcctctggtt caatccagcg cttgattggt gtttcactag
    18181 ccacccagtc agctaagcca cctgtctcaa aatccgcagc ggtcatagct gtcttgactg
    18241 ctcctggagc gataccaaag acctgaatcc cagcttcagc atagtctaga gccaactgct
    18301 tggtgaagcc agccaaggca tgcttggatg aagtataggc gtgaccacct ccacctgcta
    18361 ggctagaagc aatggaacac atattgatga tgattccctt tttattttcc agcatttgtg
    18421 tcaaataata ccgagtcaac tctactggaa taatgtagtt gatttcaaaa atctcttgaa
    18481 tgtcctgcgc cgtttgttcc aacagtggtt tgtaatcatc caaaactccg gcagtattac
    18541 acaaaacatc cacctgaggg caccagtcaa aaataggttc caagtccaag gtcaaatctc
    18601 tctgtaaaaa gtgaaaatca ccctctaaga gtggcttttc accttggtca actccataaa
    18661 cttgatagcc cttctctaaa aagaggcgag cttgagccaa tccgatccct gaactcactc
    18721 ctgtaatgag tacacgttta gtcatgcact tctacccaat ccgttgccaa aacatcacaa
    18781 actgtcgggc tccacatgga aaaaccttct ccttctccag aaacgttgat taggaaataa
    18841 ggtgtcattt caagtgcaag cccattttgc tcgatggtat caaagagttg gacatagttt
    18901 tccgcacctc cccaaccagt tcgtacatat tttctcttag cctttaaccc aggcaggatc
    18961 tcttcaaatg tcatgttttt ctcctttaat tctacattct tcatttaatt atagcaaaaa
    19021 accactttat acggcttttt gactgtgagt tattcaaacc tgctactact tacggcaaat
    19081 tattccctgc agcaagataa atttcatacc attcttttct tgttaagcta aagtttgccg
    19141 ctcggctaac ttctctcaag tgcttaggat ttgttgtacc tacgactgcc tgcatttttg
    19201 ctggataacg caatatccaa gaaatggcaa tagttgaaga ggttactcca tatttaatag
    19261 ctaaacgatc aagtacttga tttaaagctt gaaatttctc atttccaaca aagttccctt
    19321 taaaataccc gaattgcaag acagaccatg cttgaatgac cacatcgtgt aatttgcaat
    19381 attcaaaaat gctgccatct cgcatagctg cttgactatc ttccatatta acatgaaaag
    19441 ctgattcaaa tcctggagta aaagccgcac tcaattgtag ctgattaaca gctaacggct
    19501 gcttgacatc ttttttaagc aactccatca tcataggatt ttgattagaa actccaaaat
    19561 ctcgaacttt accttgttta taaaggagat caaaggcttc tgctacttgg tcagattcca
    19621 tcaaagcatc tggtcgatga aggagcaagc tatctagatg atcaatcttc aatctttgca
    19681 aaataccgtc tactgatttt ataatatagt ccttagaaaa atcaaaatag gtaaattctt
    19741 caatgcgaat gccacatttg gactgaatcc acatcttttc tcttaaatct ggacgatttt
    19801 ttaggacaag acctaacagt tcttcacaac gaccacgacc ataaatatca gccaagtcga
    19861 aggcattgat tccaacagaa agtgctgttt ctacaagctc ttcaacttct tttacagact
    19921 tatcttttat tctcatcatt ccgagaacaa tttctgataa ttctttgtca tcttgaccaa
    19981 gagttatgta tctcatcaaa tttttctcct ttaatttcta acattcttcc cttcattata
    20041 acaaaaaacc gctttgcaac ggctttttga ctatacttca ctccatttta tcttcttaaa
    20101 cccacggaac aagacaaaga ttccaataaa gaggacagct aaaggaataa cttttgtaag
    20161 gaaaacattt gaaattccca tctactcata ataacggagc agagaaccca ccacaagatg
    20221 ggcaataatc atactgacaa atggacgaaa gaccgcttct ttccaattcc aaataccgat
    20281 aactagcgaa atcgtaaaga cagacaaact atcccaggga gccggaatat aaaaggctcc
    20341 ttcttgtatg aagcttgcca ttcctacata tcctaaaaca actagaagaa ctatagtccc
    20401 aacaacaatg taagtgccaa ttttcatttt aggagaatct tggactaaac ttcttcgtaa
    20461 aattgtggcc acaagtccaa atccaatcag aaaaataaga agttgcccta aaaatgtgag
    20521 caaattgact gttaagagag gacctttaga aaaatcactt agtagttgat aataacgtaa
    20581 taccgccagg acaagaattg gcgtcaaaag ggactctttg atagaactgc gaggtgctcc
    20641 cttgagaatc tctttcatta tttttttagg attcttacct agataatcct ctgcactcat
    20701 gccatctcgt tctgcttctg agaaatctag catcatcaaa tagatctgct ctctgagata
    20761 gtcttcatca tagagaaatc cagcaagatt aaaactttcc cacaactcct caaaatactt
    20821 ttgattctcc tcagaaaact catgtagcaa agcgcttgtt tcttcgtaat acttcatttt
    20881 cttcatggtt taacccccat tcttaatccc ttctactttt tgactcaaat cgtcccattg
    20941 ttgccaaaag actgagacac gctcttctcc ttctttcatt aatgaaaaat acttccgatc
    21001 tggaccatct ggcgacgggc gcatgtcgcc tcttatccat tgattttttt ctaacttttg
    21061 caacaaagga taaatagttc ctggaacgat agtatcaaat ccagcctctc gcaaagtctg
    21121 aaccaactca taaccatacc gctctttttg accaatcata tccaagacac aaccttcaag
    21181 aacacctttt aatagctgag tttctttcat cacttctccc ttctaatcta ttttgtaata
    21241 cctactagta acttcaccta tagtatatca cttctacact agtttgtaaa gcataatagt
    21301 taatactctt cgaaaatctc ttcaaaccac gtcagcgtcg ccctaccgta tgtatggtta
    21361 ctgacttcgt cagtttcatc tacaacctca a
//
LOCUS       DAVKMJ010000037        19667 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000037 DAVKMJ010000000
VERSION     DAVKMJ010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19667
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.037"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..673
                     /locus_tag="VW348_001567"
                     /pseudo
     CDS             1..673
                     /locus_tag="VW348_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(737..1819)
                     /locus_tag="VW348_001568"
     CDS             complement(737..1819)
                     /locus_tag="VW348_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9746446.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(1816..2793)
                     /locus_tag="VW348_001569"
     CDS             complement(1816..2793)
                     /locus_tag="VW348_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEU9746447.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            3008..3385
                     /locus_tag="VW348_001570"
     CDS             3008..3385
                     /locus_tag="VW348_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEU9746448.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            3620..5011
                     /locus_tag="VW348_001571"
     CDS             3620..5011
                     /locus_tag="VW348_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEU9746449.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKVEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            5125..5967
                     /locus_tag="VW348_001572"
     CDS             5125..5967
                     /locus_tag="VW348_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEU9746450.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERENLKTIAVQSGAPRVD
                     DVDF"
     gene            6240..7001
                     /locus_tag="VW348_001573"
     CDS             6240..7001
                     /locus_tag="VW348_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEU9746451.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            7194..8111
                     /gene="glyQ"
                     /locus_tag="VW348_001574"
     CDS             7194..8111
                     /gene="glyQ"
                     /locus_tag="VW348_001574"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEU9746452.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            8323..10359
                     /locus_tag="VW348_001575"
     CDS             8323..10359
                     /locus_tag="VW348_001575"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEU9746453.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            10401..10658
                     /locus_tag="VW348_001576"
     CDS             10401..10658
                     /locus_tag="VW348_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEU9746454.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(10881..12125)
                     /locus_tag="VW348_001577"
     CDS             complement(10881..12125)
                     /locus_tag="VW348_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU9746455.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AFTGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(12144..12749)
                     /locus_tag="VW348_001578"
     CDS             complement(12144..12749)
                     /locus_tag="VW348_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEU9746456.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFTDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            complement(12809..13732)
                     /locus_tag="VW348_001579"
     CDS             complement(12809..13732)
                     /locus_tag="VW348_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEU9746457.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            14026..15405
                     /locus_tag="VW348_001580"
     CDS             14026..15405
                     /locus_tag="VW348_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEU9746458.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALAGGKIELFRNGAF
                     LVDKKQETSIPDVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            15557..16432
                     /gene="pdxS"
                     /locus_tag="VW348_001581"
     CDS             15557..16432
                     /gene="pdxS"
                     /locus_tag="VW348_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEU9746459.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            16433..17017
                     /gene="pdxT"
                     /locus_tag="VW348_001582"
     CDS             16433..17017
                     /gene="pdxT"
                     /locus_tag="VW348_001582"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEU9746460.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEDVEILATVDNQIVA
                     AQEKNMLVTSFHPELTDDAHLHQYFIEMCKEKRQ"
     gene            17574..18305
                     /locus_tag="VW348_001583"
     CDS             17574..18305
                     /locus_tag="VW348_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000247941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9746461.1"
                     /translation="MVNNVAVKVSNLSKEFLLGQDKTVSILKDISLSVNYGEFVSILG
                     VSGSGKSTLLSCLSSLSEPTSGEVVINGVNPYTLKEGKLAKFRRQDIAIIFQNYNLVP
                     ALPVLENVTLPLRLSGKSVDSNKVKKMLDSLNFKAELSSLVATLSGGEQQKVAITRAI
                     IADSKIIFADEPTGALDSVSRKLIFETLRNLASQGKCVLMVTHDIELASKTDRALILK
                     DGKISRQIIKPSADELYQALESSKD"
     gene            18323..19639
                     /locus_tag="VW348_001584"
     CDS             18323..19639
                     /locus_tag="VW348_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU9746462.1"
                     /translation="MLKLIIYQFQYSKRQWLGTIPLLFVSSLIVGTSLFGIASSIKTA
                     NINASQLFQMLIIFGGTTLFFLISNNIRLLIDIFKKDYQLWTILGASRTQLSLLVSGQ
                     FYLMAVIVSSIGTILSFIMADSYYKFLQNLLGRDELPDLVITANIQSILLSIFIVPTI
                     VGIGAYFYSSRILKISSILKPKKKKRKVTVTGFVNISVRLFLWLLCIGSIVSAGFIRN
                     KEIIEKQSSIILFLLIIHILIIQSLSPSIQMFLIKFLMRIFPTENYVINTGFWNLLSN
                     PSYLKSIQTSMSMGVTLISGFILYTQNMYSFMNTANGVNEARASFIAYMSAPIILIIT
                     SSISLTILSSNKDIEDIKQLKTLGVSRLQLFKIRIGEAIIHSVLILLVSVIFNLIILI
                     LVSIIGQFLGRSLVDISGFWQPSLIVISLLVIFYSITKGFYLFQDR"
BASE COUNT         6075 a         3494 c         4183 g         5915 t
ORIGIN      
        1 tatcaactgt tgaagcacca tggttggcga aatattatgc cacgtccaga acatcctagg
       61 aaagcagacg ctcaaaccat tgtcgcgtct aaaaataaaa tctcaattca agaagacaag
      121 aaagcgcttt aaaaccagta gaccttttca taaggttcgc ttgatgtacc aagatgaggc
      181 tggtttcggt agaatcagta aactgggatc ttgttggtct ccaataggag taggtccaca
      241 tgtccatagt cactatatac gagaatttcg ctattgttat ggagctgttg atgccccata
      301 caggcgaatc atttttctta atagctggtg gatgtaatac tgagtggatg aacgtctttt
      361 tagaagagct ttcacaagct tatccagatg attatttttt actcgttatg gacaatgcta
      421 tatggcataa atcaagtacc ttaaagattc cgactaatat tgattttacc tttattcctc
      481 catacacacc agagatgaac ccattgaaca agtgtggaaa gagattcgta aacgtggatt
      541 taagaataaa gcctttcgaa ctttggaaga tgtcatgaat caactccaag atgtcataca
      601 aggactggag aaggaggtga taaagtccat cgttaatcgg agatggaata gaatgctttt
      661 tgaaagcaga tgagtataaa attgaattgc ttataaaaaa gctccataca ctggatgtgt
      721 atagagcaat ggggctttat ttgatataga gttcttggtt ttttaggaca atttctcgga
      781 tacttgcaaa ctttttaagt tttttgattt cttctggatg agtgacgaga gtaataacat
      841 atccttcctt gcccatacgg ccagtacggc cagcacggtg tgtgtaggtt tcgctatctc
      901 taggaatatc aaagtttacg acacattcta ggctatcgat atcaattcca cgagccaaaa
      961 ggtcagttgc aagaagcagg gttagttggt tatctttaaa cttttctaag atgatttttc
     1021 taaatttaac attaacatca ctagcgaggg aaacagccaa tatatcacga tactgtagtt
     1081 tttcctcggc attcccaagg tctgacaggc tattgaagaa gactagacca cggaaatcct
     1141 ctacatgagc cagttttcgc agcatatcca ctcgatgacg ttggtctacc tgcatgtaga
     1201 aatgctggat attgtccaat ttttgatcag agagatcaat agtgcgtgta ttcggcacaa
     1261 tcttttcttg gtcaaacttg gtcgtggcac tcatgtagac cagttggtgg tcacgaggtg
     1321 cgtagtgagt gattttttct acaaagtgaa tctgagaatc atctagtaat tggtcaaatt
     1381 catccaggat gatggtttcc acattcatca tcttgatttt tttaagttta atgagttcaa
     1441 agatacggcc aggagttcca atcagaattt ctggcccctt tttaagacgt tcaatttgtc
     1501 gtttctgact tgaacctgaa aggaagagtt gagcagtcaa tccgatagct tctgcccacg
     1561 ttttacatac atcaaaaatc tgtccagcaa gttccgtatt tggtgctaga atcaagagtt
     1621 gttgggcttt tttcttttgt agtctgagaa gacttggtag gagatacgct agggtcttac
     1681 cagttccggt ttggctcact cctaggaggt tttctccagc aagaaggggc tcaaatagtt
     1741 gagtttgaat gggggtgaat tcttggaaac cgagttggtc actcagttct tgccattcag
     1801 tcggtagttt ggttttcatt tttctgcctc aaatctaatg ccagcagtct ggcgcatggt
     1861 atatagtagc tcatgaacag agcctgcatc atacagccaa gtttggtaga gattcagatc
     1921 tggttgctgg atcatgtgtg caaatgcagc gacttcctca gtcatcgtat gaggagcctg
     1981 ttggatagga agctggactt gatttccttg gtggtcggta aaaatagctg agcgaatatg
     2041 ctcaatcgtg ttgagagtca aggttccatc tgttgtataa atctcgcaag gaagattgga
     2101 agtgatgttt tttccagcct tgatgtgaac ttgatagtct gggtagaaga ggataccatc
     2161 tccatttagg tcaatgctat tgtcaagctg ttgagcatgg taagtcgcgt cattagcttt
     2221 ttcaaaaaga cgaacagcag catagagggg ataaatcccc aaatccatga gggctccacc
     2281 agcaaaacgg tctgaaaaga catttggtgt ttgtccagcc aacaagtcag gcatcttgga
     2341 agagtatttg gcatagttga aatctgctcc taacacttgc ttatctgcta aaaagttttt
     2401 gatagtagta aaggctttct cgtggtaatt acgagctgct tcaaagataa aacagttatt
     2461 tttttcagct gtttgaatca aatcaaacca ttcttgtggt tgagtgacag ctggcttttc
     2521 gagaataaca tgtttaccag cagacaaggc agcttttgcc tgagcaaaat gtaaggagtt
     2581 tggactggcg atatagacta aatcaaaaga agatttgaag aagacttcta attgatcgaa
     2641 tagttggata ttctgatagc gagaagcaaa ggttgctgca gtttctagtt ttctagaata
     2701 gattgcgacc agttggtatt ctccactggt atgggctgct tctatgaaat gatggctgat
     2761 agcgccagtt ccgatgacac ctaattttag cataaatact ccttttccga ttttaaatcc
     2821 ttctttcatt ataacataga tagacgggac tatccaacag agaggagaaa atttcaaata
     2881 agctattagc tttcttttcc gaataaatag atagaagcat agaatctagc aaacctagat
     2941 ttaaaaatgt gctataatag aaggaggaaa aggaggattc tcagacatcc aggtatcagc
     3001 ccaactaatg atttgtcaat ttatccgcga tatgctggac ttgccagcaa aaaatgtgac
     3061 gattttggag ggaagtaaca ttcacgtctt gccttccatg ccctactcag cgcaagattt
     3121 ctatactagt atagacgtct tggcggagtt agataatgga atccaagtta tcatcgaaat
     3181 tcaggttcat catcagaatt ttttcatcaa tcgcctatgg gcttatctgt gcagtcaggt
     3241 taatcaaaac ctagaaaaaa ttcgccaacg tgaaggtgat acccaccaga gctacaaaca
     3301 aatcgcacca gtatacgcta tcgcaattgt cgatagtaat tacttctcag atgacctagc
     3361 ttttcatagt tttatagtaa aatgaaatga gaacaggaca aatcgatcag gacaatcaaa
     3421 tcgatttcta acaatgtttt agaagtatag gtctactatt ctagcttcaa tctactagaa
     3481 attccataga tataaaacta cataatctct acagatacgg atgttggagt tgatgtaaga
     3541 tgctttggct tgctagagga attgtggatt gccaaattgt atcattgaaa ttattgctca
     3601 aatttgttat gatataaata tgaataaaag tagactagga cgtggcagac acgggaaaac
     3661 gagacatgta ttattggctt tgattggtat tttagcaatt tctatttgcc tattaggcgg
     3721 atttattgct tttaagatct accagcaaaa aagttttgag caaaagattg aatcgctcaa
     3781 aaaagagaaa gatgatcaat tgagtgaggg aaatcagaag gagcattttc gtcaggggca
     3841 agccgaagtg attgcctatt atcctctcca aggggagaaa gtgatttcct ctgttaggga
     3901 gttgataaat caagatgtta aggacaagct agaaagtaag gacaatcttg ttttctacta
     3961 tacagagcaa gaagagtcag gtttaaaggg agtcgttaat cgtaatgtga ccaaacaaat
     4021 ctatgattta gttgctttta aggttgaaga gactgaaaag accagtctag gaaaggttca
     4081 cttaacagaa gatggccaac cttttacact tgaccaactg ttttcagatg ctagtaaggc
     4141 taaggaacag ctgataaaag agttgacctc cttcatagag gataaaaaaa tagagcaaga
     4201 ccagagtgag cagattgtaa aaaacttctc tgaccaagac ttgtctgcat ggaattttga
     4261 ttacaaggat agtcagatta tcctttatcc aagtcctgtg gttgaaaatt tagaagagat
     4321 agccttgcca gtatctgctt tctttgatgt tatccaatct tcgtacttac tcgaaaaaga
     4381 tgcggccttg taccaatctt actttgataa gaaatatcaa aaagttgtcg ctctaacctt
     4441 tgatgatggt ccaaatccag caacgacccc gcaggtatta gagaccctag ctaaatatga
     4501 tattaaagcg actttctttg tgcttgggaa aaatgtttct gggaatgagg acttggtgaa
     4561 gaggataaaa tctgaaggtc atgttgttgg aaaccatagt tggagccatc cgattctctc
     4621 gcaactctct cttgatgaag ctaaaaagca gattactgat actgaggatg tgctaactaa
     4681 agtgctgggt tctagttcta aactcatgcg tccaccttat ggtgctatta cagatgatat
     4741 tcgcaatagc ttggatttga gctttatcat gtgggatgtg gatagtctgg actggaagag
     4801 taaaaatgaa gcatctattt tgacagaaat tcagcatcaa gtagctaacg gctctatcgt
     4861 tttgatgcat gatattcaca gtccgacagt caatgccttg ccaagggtca ttgagtattt
     4921 gaaaaatcaa ggttatacct ttgtgaccat accagagatg ctcaatactc gcctaaaagc
     4981 tcatgagctg tactatagtc gtgatgaata agcaagaaaa aataggtctg ttagatattt
     5041 gacagactta ttttttacag aagatagtac tacttaaaaa atgttttatg ctataattga
     5101 tgaataaaat agaaggagaa gcatatgaat acctatcaat taaataatgg agtagaaatt
     5161 ccagtattgg gatttggaac ttttaaggct aaggatggag aagaagccta tcgtgcagtg
     5221 ttagaagcct tgaaggctgg ttatcgtcat attgatacgg cggcgattta tcagaatgaa
     5281 gaaagtgttg gtcaagcaat caaagatagc ggagttccac gtgaagaaat gttcgtaact
     5341 accaagcttt ggaatagtca gcaaacctat gagcaaactc gtcaagcttt ggaaaaatct
     5401 atagaaaaac tgggcttgga ttatttggat ttgtatttga ttcattggcc gaacccaaaa
     5461 ccgctcagag aaaatgacgc atggaaaact cgcaatgcgg aagtttggag agcgatggaa
     5521 gacctctatc aagaagggaa aatccgtgct atcggcgtta gcaattttct tccccatcat
     5581 ttggatgcct tgcttgaaac tgcaactatc gttcctgcgg tcaatcaagt tcgcttggcg
     5641 ccaggtgtgt atcaagatca agtcgtagct tactgtcgtg aaaagggaat tttattggaa
     5701 gcttgggggc cttttggtca gggagaacta tttgatagca agcaagtgca agaaatcgca
     5761 gcaaatcacg gaaaatcgat tgctcagata gccttggcct ggagcttggc agaaggattt
     5821 ttaccacttc caaaatctgt cacaacctct cgtattcaag ctaatcttga ttgctttgga
     5881 attgaactga gtcatgagga gagagaaaac ttaaaaacga ttgctgttca atcgggtgct
     5941 ccacgagttg atgatgtgga tttctagaaa atcataaaaa gaattgtaca ttattctaat
     6001 ttttgatata atagtcagca ggaaagaaag tcttatggcg ttcttcaagc gagcttggga
     6061 tagtgggagc caagtagggc aaaataatga gctggcgctt tctgtagtat tttcaaaaac
     6121 aatgaagtaa taaattaggg tggaaccgcg tttctgacgc ccctaggtta aatcaaccta
     6181 ggattgtcgg acgcggttct tttgcttatt cagtctattg tgtgaaagaa aggagagccg
     6241 tggacaacct ttatcttgta aaagacgata gtcaactagc tacatttcgt gattttgtag
     6301 taagaaatac tgaaaagttg aaagattatc aatctttttt aaagaatgaa cttgcagtct
     6361 gtgatttacc gcaagccgtt atttggtcag attttaatgc tgctacacag attattaggg
     6421 aaagcgctgt tccagcctat acaaataata gacgaatggt tatggcgcct gatttagctg
     6481 tttggaaaga gttgtatttg tatcaattga tggactacga gtgttctcag caaactcaag
     6541 caatagaaag tcactatcat tctttatctg aaaatttcct cttacagatt gtaggacatg
     6601 agttagctca ttggtcggag cattttttag atgattttga tggttatgac tcttatatct
     6661 ggttcgaaga ggggatggtt gaatatatta gtcgcaagta tttcttgaca gaagaggaat
     6721 ttcaagcgga aaaaatttgt aatcaatctc tcgtagaact ttttcagaag aagtatggtt
     6781 ggcattcatt gaatgatttt ggttcttcga cttatgataa gaactatgca agtatttttt
     6841 atgaatactg gcgcagcttt ttgacagtag ataagttggt agaaaattta ggtagtgtac
     6901 aagcggtctt agattcttat catttatggg caaatacaga aaaaactttt cccttgttag
     6961 attggtttgt tcagcagaaa ttaattgaaa aagaaatata aaaactaaag gagtaaacaa
     7021 tgtctaagaa attgacattt cactgcgtca gtggcagaaa cctccttaca gtcggactgc
     7081 cccacgctca gcactagagt gcctgagcta gacgcagtac taactcgtct tgcctcgtat
     7141 gatcgacgag gcagactcat gtcgcaagta atttatataa aaaggagtaa acaatgtcta
     7201 agaaattgac tttccaggaa atcatcctta ctttgcaaca attttggaat gaccaaggtt
     7261 gtatgcttat gcaggcttat gataatgaaa aaggtgcggg aacaatgagt ccttacactt
     7321 tccttcgtgc tatcggacct gagccatgga atgcagctta tgtagagcca tcacgtcgtc
     7381 ctgctgacgg tcgttatggg gaaaacccta accgtctcta ccaacaccac caattccagg
     7441 tggtcatgaa gccttctcca tcaaatatcc aagaacttta ccttgaatct ttggaaaaat
     7501 tgggaatcaa tcctttggag cacgatattc gttttgttga ggacaactgg gaaaacccat
     7561 caactggttc agctggtctt ggttgggaag tttggcttga cggaatggaa atcactcagt
     7621 tcacttattt ccaacaagtc ggtggattgg caactggccc tgtgactgcg gaagttacct
     7681 atggtttgga gcgcttggct tcttacattc aagaagtaga ctctgtctat gatatcgagt
     7741 gggctgatgg tgtaaaatac ggagaaatct ttatccagcc tgagtatgag cactcaaaat
     7801 attcatttga aatttcggac caagaaatgt tgcttgaaaa ctttgataag tttgaaaaag
     7861 aagctggtcg tgcattagaa gaaggcttgg tacaccctgc ctatgactat gttctcaaat
     7921 gttcacatac ctttaatctg cttgacgcgc gtggtgccgt atctgtaaca gagcgtgcag
     7981 gctatatcgc tcgtatccgt aacttggccc gtgtcgtagc caaaaccttt gtcgcagaac
     8041 gcaaacgcct aggctaccca cttttggatg aagaaacaag agctaaactc ctagcagaag
     8101 acgcagaata aagagagtga caaattacga aaatgggcga acagagtgag ccctgagcca
     8161 gttgccgcag tgatgaaggt atccttagtg aaactaagga tactaggcaa aattggagac
     8221 ttttggctcc aattttagca atgaaacaac gaagttggtt gcttgcgtgc caatcacata
     8281 aggcaaactg gaaaataaaa agatactttt cggagaaaaa acatgacaaa aaacttatta
     8341 gtagaactcg gtcttgaaga attaccagcc tatgttgtca caccaagtga aaaacaacta
     8401 ggcgaaaaaa tggcagcctt cctcaaggaa aaccgcctgt cttttgaagc cattcaaacc
     8461 ttctcaacac cacgtcgttt ggctgttcgt gtgactggtt tatcagacaa acagtctgat
     8521 ttgacagaag atttcaaggg accagcaaag aaaattgcct tggatagtga tggaaacttc
     8581 accaaagcag ctcaaggatt tgtccgtggg aaaggtttga ctgttgaaga tatcgaattc
     8641 cgtgaaatta agggtgaaga atatgtctat gtcactaagg aagaagttgg ccaatcagtt
     8701 gaagccattg ttcctggtgt tgtagatgtc ttgaagtcat tgactttccc tgtcagcatg
     8761 cactgggctg gaaatagctt tgaatacatc cgccctgttc acactttaac tgttctcttg
     8821 gatgagcaag agtttgactt ggatttcctt gatatcaagg gaagtcgtgt gagccgtggc
     8881 catcgtttct tggggaaaga aaccaaaatt cagtcagcat tgagctatga agaagacctt
     8941 cgtaagcagt ttgtaatcgc agatccatgt gaacgtgagc aaatgattgt tgaccaaatc
     9001 aaggaaattg aggcaaaaca tggtgtacgt atcgaaattg atgcggattt gctgaatgaa
     9061 gtcttgaatt tggttgaata cccaactgcc ttcatgggaa gttttgatgc taaatacctt
     9121 gaagttccag aagaagtctt ggtgacttct atgaaggaac accagcgtta ctttgttgtt
     9181 cgtgatcaag atggaaaact cttgccaaac ttcatttctg ttcgtaacgg aaacgcagag
     9241 cgtttgaaaa atgtcatcaa aggaaatgaa aaagtcttag tagcccgctt ggaagacgga
     9301 gaattcttct ggcgtgaaga ccaaaaattg gtgatttcag atcttgttga aaaattaaac
     9361 aatgtcacct tccatgagaa gattggttcc cttcgtgaac acatgattcg tacgggtcaa
     9421 atcactgtac ttttggcaga aaaagctggt ttgtcagtgg atgaaacagt tgaccttgct
     9481 cgtgcagcag ccatttacaa gtttgacttg ttgacaggta tggttggtga atttgacgaa
     9541 ctccaaggaa ttatgggtga aaaatacacc cttcttgctg gtgaaactcc agcggtggca
     9601 gctgctattc gtgaacacta catgcctaca tcagctgaag gagaacttcc agagagcaag
     9661 gtcggcgcag ttctagccat tgcagacaaa ttggatacga ttttgagttt cttctcagta
     9721 ggattgattc catcaggttc taatgaccct tatgcccttc gtcgtgcaac tcaaggtgtg
     9781 gttcgtatct tggatgcctt tggttggcac attgctatgg atgagctgat tgatagcctt
     9841 tatgcattga aatttgacag tttgacttat gaaaataaag cagaggttat ggactttatc
     9901 aaggctcgtg ttgataagat gatgggctct actccaaaag atatcaagga agcagttctt
     9961 gcaggttcaa actttgttgt ggcagatatg ttggaagcag caagtgctct cgtagaagta
    10021 agcaaggaag aagattttaa accatctgtt gaatcacttt ctcgtgcctt taacctggct
    10081 gagaaggcag aaggggttgc tacagttgat tcagcactat ttgagaatga ccaagaaaaa
    10141 gctttggcag aagcagtaga aacactcgtt ttatcaggac ctgcaagtca gcaattgaaa
    10201 caactctttg cgcttagccc agtcattgat gctttctttg aaaatactat ggtaatggct
    10261 gaagatcagg ctgtccgtca aaatcgtttg gcaatcttgt cacaactaac caagaaagca
    10321 gctaagtttg cttgttttaa ccaaattaac actaaataaa atttgataaa cggactttat
    10381 cttattacaa aggagaagaa atggatccga aaaaaattgc tcgtatcaat gagcttgcta
    10441 aaaagaaaaa aacagaaggc ttaacaccag aagaaaaagt ggaacaagcc aaactacgtg
    10501 aggagtacat cgaaggttat cgccgcgctg ttcgtcacca cattgaagga atcaaaattg
    10561 tggacgaaga aggaaacgat gttacaccag aaaaactacg ccaagtacaa cgtgaaaaag
    10621 gattacatgg ccgtagtctt gatgatccaa attcataata atactcttcg aaaatcaaat
    10681 tcaaaccacg tcagcttcac cttgccgtac ttaagtacag cctgcggcta gcttcctagt
    10741 ttgctctttg attttcattg agtatatgta ttctttcttt taacaaagat agatgaaacg
    10801 ataacaaaga gactagcagt ttgtgtttgc tagtcttttt tcgctaaaaa aggaaccata
    10861 atggttccta aaaactatca ttagtaactt gcaccggctg tagcgtctgc gtcaccaccg
    10921 tggcctccag catcccctga atcagaagcg ccagaagtag catcggcgtc tccatgacct
    10981 ccggcagcag gagcaaatgg tccgctacca cccaccaaac gttgaccagt ctcttttagg
    11041 taccagtcaa gccatggttg gaagttaaag acgatttcat tgataccagc gtatgatcca
    11101 tcaggatagt acattgcttg gtagttgtga gtgttgataa cacctgcagg agaacctgga
    11161 acgatcgtac ggacgtattc ttggtttccg ttgcgaagtg ttccgataac ccactctacg
    11221 ttcttcatac gtgctggtgg aagagaacca tgaacagtcg acatacggct acctgattga
    11281 ggtggtacac gtttagcgaa catagtgtct ggatcttggt gagcgttgtt gtagtagagg
    11341 aattggttgt tgtcgtcagc gtatgtcaat tcaaatggca tagctttcaa gaacatatca
    11401 atttggttaa ctgttaggat accgtggtcc aatttgacat aggtatcacc agaaacagca
    11461 ccagtgaatg ctgcaacttt ttctacccat tctggatcgt cagggtcaac ttctgtgatg
    11521 gttgtagcga ttggttttcc acaatccaag tcttctgatt cgattggttt tggttttttc
    11581 aatttcgaaa cgactcctac gtatttaaca aagttatcta agcaagtttc aaggaattta
    11641 acagtgcctt cgttggtgat atttccgttg ttatcaaaag cttccttagc tttaccaaga
    11701 aggaattcgt tacctggaag cgtgtaggca ttaacacctg gagcatcaag gattttacga
    11761 aggtgaactt gagcacgtga tgttccttgg tcatagtatg atgcacccac aatcataaca
    11821 ggcttgtttt caaatggatg aacttcgtat gaaagccatt caagtacaga tttgagtgaa
    11881 gctgagatag tgtggttatg ctcaggagta gcaatgataa caccatctgc acgagtaatt
    11941 ttgttatata aataacgtaa ttggaaactt tcatcccatt tttcatcttg gttaaacatt
    12001 ggaacttcgt caatttcaag aacttctaat tcaaatttga gtttgaagta gcgacggata
    12061 aattccaaga gcttacggtt atatgattga tcgtagtttg atccaacaag tccaacaaat
    12121 ttcattcttt ttggtctcct atcttacaaa ttttcccagt caaagtcttc agcatctttg
    12181 cgaagtaatt cttgtgcatt acgtaatttt tctgtgattt ttacaaagat acggaagtca
    12241 tcaaagatgg catccaattt cttgataaca tcaaggtcaa ccaagtcgcc acttgggtta
    12301 aatgcttgaa gagagtgtga gagcaagaat tcatctggaa gaacatttgc cttgatttca
    12361 ggagcattca agatttgacg aagttgcaat tgggcacgag atgaaccaag cgtaccgtaa
    12421 gaagcacctg taatcatgat tggtttgttc aaaagtgggt aaataccata agataaccaa
    12481 gcaagagcgc tcatcaaaac agctggaata gagtgatcat actcaggagt accgataata
    12541 acgccatctg cctcttcgat tttagcagca atttccaata tttcagcagg tacttgcttg
    12601 tcagctggtt tgttgaagac aggaatggcc ttgatttcaa caagttcaat ttcagctttg
    12661 tcagtaaagt gtttttgcat gtattgaagc aattgacggt ttgtagaacg ttttgaattt
    12721 gttccaacaa tagcaataag ttttaacatg agatttcctt tctcttttta cataatacaa
    12781 ttttaaaatt ccattgaaac agttgtctct atagagtagg aattcctgaa gaacagctta
    12841 ggtggccttc tttatcgatg aggatgactt cgatgccctc caaactttcg acttgccaga
    12901 ggatagaagc aggtctttct ccaaagagtc gagtcgtcca gatttcgcca tcgactgatt
    12961 tatcagagat gattgttaga ctcgctagtt ccgtttcaac aggatatcct gtttgactgt
    13021 caaaaatgtg atggtaatct tgtccatcga cggtcaggtg acgttcataa atgcctgaag
    13081 tcacgacaga tttattgaca acagggatgg tcattaaatg atttccccta ggattggctg
    13141 ggtcttgaat cccgatttgc catgggttat cccctcttgc ctgatttttt ccaatggtca
    13201 ggatattccc tcccagattg atcaaggcag aagtcacccc ctctttccta agaaattggg
    13261 caaccttatc cgcactgtat cctttggcta aacaacctag atcgatcttc attcctttct
    13321 gttttaaaaa cacagtagaa gtagaagaat ctaactcgat accatgagga ttgattagag
    13381 gcagcaccga ttcaatttct tgaggctggg cgaccttggc atctgaaaaa ccgatacgcc
    13441 aggtttgaat taagggacca atgctgatat tgaggtggct agagagcgct aggctatgct
    13501 ctaacccaag tgaaatcagc tcaaacaggt ctggatgaac cgtgacgggg gctattcctg
    13561 cttgataatt gatttccatc aactcagatt cttgactatt ggcgttgaag cggtattcaa
    13621 gttctttgag caagtcaaag gatttttgga gaaagatatc ggcttgctca tccactaatg
    13681 aaatagtgat agtagtcccc attagccgtt cagaatgtga acgaagagtc aagctaccaa
    13741 ctcctttctc ttatagaaaa taagttgtaa tatcaaataa tcatctaaat tgaagccctt
    13801 acatttcatt ttcatgttat tataatacca taaagttaga attttcacaa acaaaatttg
    13861 gaaaaagtca agaaatatgc tcataaaatt catcaggctt gaaaacagga taaatgggga
    13921 attatttttg ataaaaaatg ctgaaataat agtacccccc ttgtaaacgc taacggtaaa
    13981 tggtatacta gtaaggtaaa tttagaatga aggcaggaaa tttttatgag taaaatcgtt
    14041 gtagtcggtg ctaaccacgc tggtacagca tgtatcaata ccatgttgga taattttgga
    14101 aatgagaacg aaattgttgt atttgaccaa aactctaaca tctctttcct aggatgtgga
    14161 atggctcttt ggattggtga acaaattgac ggtgctgaag gcttgttcta ttctgataaa
    14221 gaaaaattgg aagctaaagg tgctaaagtt tacatgaact cacctgttct ttcaatcgac
    14281 tatgataaca aagtagttac agcggaagtt gaaggaaaag agcacaaaga atcatacgaa
    14341 aaattgattt tcgctacagg ttctacacca atcttgccac caatcgaagg tgttgaaatt
    14401 gttaaaggaa accgcgaatt taaagcaact cttgaaaacg tacaattcgt gaaattgtac
    14461 caaaatgctg aagaagttat caataaactt tctgacaaga gccaacacct cgaccgtatc
    14521 gccgttgttg gtggtggtta catcggtgtt gaacttgctg aagcctttga acgtcttgga
    14581 aaagaagttg tccttgttga tatcgttgat actgtcttga acggttacta tgacaaagac
    14641 ttcacacaaa tgatggcgaa gaacttggaa gatcacaaca tccgcttggc tctaggtcaa
    14701 actgttaaag caatcgaagg tgacggtaaa gttgaacgct tgattactga caaagaaagc
    14761 tttgacgtgg atatggttat ccttgcagtt ggtttccgtc caaacacagc ccttgcaggt
    14821 ggtaagatcg aactcttccg caacggtgcc ttccttgtag acaagaaaca agaaacatct
    14881 atcccagacg tttacgctgt tggtgactgt gcgactgttt atgacaatgc tcgtaaagat
    14941 acaagctata tcgctcttgc ttcaaatgct gttcgcactg gtatcgttgg tgcctacaat
    15001 gcttgtggac atgaattgga aggaatcggt gttcaaggtt caaatggtat ctcaatctac
    15061 ggtcttcaca tggtttcaac tggtttgact cttgaaaaag cgaaagctgc tggttacaac
    15121 gcaactgaaa caggctttaa cgatcttcaa aaaccagaat tcatgaaaca tgacaaccat
    15181 gaagtagcaa ttaagattgt ctttgacaaa gatagccgtg aaattcttgg tgcccaaatg
    15241 gtttcccatg atattgcaat tagcatggga atccacatgt tctcacttgc tatccaagag
    15301 catgtgacaa ttgataaatt ggcattgaca gacctcttct tcttgccaca cttcaacaaa
    15361 ccatacaact acatcacaat ggctgccctt acggctgaaa aataaaaatg aatgagctat
    15421 ctggccttaa gttaaggtca gatagttttt agctaatctg tccccataca attatagttt
    15481 ttttatcttg tgcttcattc tgttctgact taaaatgaaa aggtagctac caatacaaat
    15541 gatgaggata aaacaaatga ctgaaaatcg ttatgaacta aataaaaact tggcacagat
    15601 gctcaagggt ggtgttatta tggatgtgca gaatcctgaa caggctcgta tcgcagaagc
    15661 tgctggtgcg gcagctgtga tggccttgga acgaattccg gctgatattc gtgcagctgg
    15721 aggagtttcc cgcatgagcg acccaaagat gattaaggaa atccaagaag cggttagtat
    15781 tccagtaatg gctaaggtca gaatcgggca ttttgttgaa gctcagattt tagaggctat
    15841 tgaaattgat tatatcgacg agagtgaagt tctatctcca gctgatgacc gtttccatgt
    15901 ggacaagaaa gaattccaag ttccttttgt ctgtggtgct aaggatttgg gtgaagcctt
    15961 gcgtcgtatc gctgaaggtg cttccatgat tcgtaccaaa ggagaaccag ggacagggga
    16021 tatcgtccaa gctgttcgtc atatgcgtat gatgaatcag gaaattcgcc gcattcaaaa
    16081 cttacgtgag gacgagcttt atgttgctgc caaggatttg caagtccctg tagaattggt
    16141 ccaatatgtt catgaacatg gaaaattgcc agttgtaaat ttcgctgctg gaggtgttgc
    16201 aacgccagca gatgctgcgt taatgatgca actaggggca gagggggtct ttgtcggttc
    16261 aggtattttc aagtcaggag atcctgttaa acgagcgagt gccattgtta aggctgtgac
    16321 taacttccgt aatcctcaaa tcctagctca aatctctgaa gatttaggag aagccatggt
    16381 tggtattaat gaaaatgaaa tccaaattct catggctgaa cgaggaaaat agatgaaaat
    16441 cggaatattg gccttgcaag gggcctttgc agaacatgca aaagtgctag atcaattagg
    16501 tgtcgagagt gtagaactca gaaatctaga tgattttcag caagatcaga gtgacttgtc
    16561 gggtttgatt ttgcctggtg gtgagtctac aaccatgggc aagctcttac gtgaccagaa
    16621 catgctactt cccatccgag aagccattct atctggctta ccagtgtttg ggacctgtgc
    16681 gggcttaatt ttgctggcta aggaaatcac ttctcagaaa gagagtcatc taggaactat
    16741 ggatatggtg gtcgagcgta atgcttatgg gcgccaatta ggaagtttct acacggaagc
    16801 agaatgtaag ggagttggca agattccaat gacctttatc cgtggtccaa ttatcagcag
    16861 tgttggagaa gatgtagaaa ttctagcaac agttgataat caaatcgttg cagcccaaga
    16921 aaaaaatatg ttggtaactt cttttcatcc agaattgaca gatgatgctc acttacacca
    16981 gtactttatc gaaatgtgta aagaaaaaag acagtaaaaa agctcaaaaa atcacttcct
    17041 gtgctatact gtaattgaaa tttttttagt ttttgcgtta gaactgtttc ctcagtccta
    17101 gcgccttttc tttttgataa gtctgcttgg tggagagtag tttgtaaacg attctgagaa
    17161 tcttatgagc acaagcaatg acggctttca tcttgcttcc tctttgggaa attcgattgt
    17221 aaaactctaa gcaggcagag cctgcttaga gttttacata tgctactatc tttgttatag
    17281 ctaacttaaa ttctcattta ttaagtatac ctaagtttta tgtttaaatt ttgtatagaa
    17341 tagttgtatc acttaacaaa gctatgttta cgctttcaat caagtctcat ttatgatact
    17401 attatggtaa tagaaaaaat tcttagttcg ctaaagacct ttattcgaga tccagaggaa
    17461 atagaaattt tatccattaa aaatacgttt cataagttac ttacttgata ttaatagaat
    17521 tccaatattg tataattaaa tcaaagatga cactggaatc aggaggattt attatggtta
    17581 ataatgtagc tgttaaagtc tcaaaccttt caaaagaatt tttgttaggg caagacaaaa
    17641 ctgtctctat tttgaaagat atttccttat ctgtcaatta tggggaattt gtatcaatac
    17701 ttggtgtcag tggttctgga aagtctactt tgctaagttg cttatcaagt ttatctgaac
    17761 caacaagtgg cgaagttgtt atcaatggtg taaatccata taccttaaaa gaagggaagc
    17821 ttgctaaatt tagaagacaa gatattgcaa taatttttca aaactataat ctggtacctg
    17881 ctctacctgt actagaaaat gttacacttc ctctgagact atcaggaaag agtgttgata
    17941 gcaataaagt aaaaaaaatg ttggatagtt tgaattttaa agcagaacta tcatcattag
    18001 ttgctacctt atcaggtgga gaacagcaaa aagtggctat tactcgtgca ataatagctg
    18061 atagtaaaat tatttttgct gatgagccaa caggagctct ggacagcgtc tcaagaaaac
    18121 ttatatttga aacacttcgt aatttagcga gtcaaggaaa atgtgttctt atggtcactc
    18181 atgatattga gttggcttca aaaactgaca gagcactcat tttaaaagac ggaaaaatat
    18241 ctcgacaaat tattaaacct tcagctgatg agctctacca agcacttgaa agtagtaaag
    18301 attaatttga ggaggattta ttatgctaaa attaatcatt taccaatttc agtactcaaa
    18361 aagacaatgg ttaggaacaa taccattact atttgtatct agcctgattg ttggaacatc
    18421 tttatttggt attgctagtt caatcaagac tgctaatatt aacgcttcac aactttttca
    18481 aatgctaata atttttggcg ggactactct atttttcctt atttcaaata atataagact
    18541 gctaatagat atctttaaaa aggattacca attatggact atcttaggcg caagcagaac
    18601 tcagctatct ttattagtat ctggacagtt ttatttaatg gcagtgattg ttagtagtat
    18661 tggtacaata ctttcattta tcatggcaga tagttattac aaatttttac aaaatttatt
    18721 aggaagagat gagttacctg atttagttat tacagccaac attcaatcaa ttttattgag
    18781 tatttttata gtcccaacaa ttgtcgggat aggggcttac ttttattcaa gtcgaatact
    18841 taaaatatca tcaatattaa aaccaaaaaa gaaaaaaaga aaagttacag taactggatt
    18901 tgttaacatc tctgttcgtt tattcctatg gctactatgt ataggttcta ttgtttcagc
    18961 aggttttatc agaaacaaag aaataattga aaaacagtca agcataatat tatttttatt
    19021 aattattcac atccttatta ttcaatcact atctccatca attcaaatgt ttctaataaa
    19081 atttttaatg aggatatttc caactgaaaa ttatgtaatt aatacaggct tttggaatct
    19141 actatccaat cctagctatt tgaaaagtat acaaacttca atgagcatgg gagtaactct
    19201 catttctggg tttattcttt acacccaaaa tatgtattca ttcatgaata cagcaaacgg
    19261 agtaaacgaa gcaagagctt cctttattgc ttatatgtct gcaccaatta ttctgattat
    19321 tactagttct atttctctta caattttatc ttctaataaa gatattgagg acattaaaca
    19381 gttaaagaca ctgggagtgt caagattaca actttttaaa atacgtatag gcgaggcaat
    19441 aatacattcg gtgttaattt tattagtgtc agtaattttc aatttaatta ttttaatttt
    19501 agttagcatt attggccaat ttttaggtcg tagtttagta gatatatcag gtttctggca
    19561 accgagtctt atagttattt ctttgttagt tattttttat agtattacaa agggatttta
    19621 tttatttcaa gatagataaa ttggaatagt tactgaacca aaaagaa
//
LOCUS       DAVKMJ010000038        19507 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000038 DAVKMJ010000000
VERSION     DAVKMJ010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19507
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.038"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..752)
                     /locus_tag="VW348_001585"
     CDS             complement(<1..752)
                     /locus_tag="VW348_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9746463.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNTPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQI
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHAQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            complement(749..2074)
                     /locus_tag="VW348_001586"
     CDS             complement(749..2074)
                     /locus_tag="VW348_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEU9746464.1"
                     /translation="MDFFLLVDLILYFLIISHSYRLICKDQINRKELFFFGAYTLLTE
                     IVLDFPFYLLYLDGLGIATFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYYGLFFFVVTVLTYFVTLKIIYYFHLELAYFDKDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRVYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKRKFE"
     gene            complement(2087..2227)
                     /gene="comC"
                     /locus_tag="VW348_001587"
     CDS             complement(2087..2227)
                     /gene="comC"
                     /locus_tag="VW348_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEU9746465.1"
                     /translation="MKNTVKLEQFVALKEKDLQNIQGGEMRKMNEKSFNIFNFFNFFR
                     RR"
     gene            complement(2392..2465)
                     /locus_tag="VW348_001588"
     tRNA            complement(2392..2465)
                     /locus_tag="VW348_001588"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2429..2431),aa:Arg,seq:tct)
     gene            complement(2509..2988)
                     /gene="rlmH"
                     /locus_tag="VW348_001589"
     CDS             complement(2509..2988)
                     /gene="rlmH"
                     /locus_tag="VW348_001589"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEU9746466.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            3171..4352
                     /locus_tag="VW348_001590"
     CDS             3171..4352
                     /locus_tag="VW348_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEU9746467.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            4410..5168
                     /locus_tag="VW348_001591"
     CDS             4410..5168
                     /locus_tag="VW348_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEU9746468.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNYFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIIYFSNQEEYSRIINSLK"
     gene            5381..6742
                     /gene="dnaA"
                     /locus_tag="VW348_001592"
     CDS             5381..6742
                     /gene="dnaA"
                     /locus_tag="VW348_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEU9746469.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            6901..8037
                     /gene="dnaN"
                     /locus_tag="VW348_001593"
     CDS             6901..8037
                     /gene="dnaN"
                     /locus_tag="VW348_001593"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEU9746470.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTIKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            8102..8296
                     /locus_tag="VW348_001594"
     CDS             8102..8296
                     /locus_tag="VW348_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEU9746471.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            8380..9495
                     /gene="ychF"
                     /locus_tag="VW348_001595"
     CDS             8380..9495
                     /gene="ychF"
                     /locus_tag="VW348_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEU9746472.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLIESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYESEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            9566..10135
                     /locus_tag="VW348_001596"
     CDS             9566..10135
                     /locus_tag="VW348_001596"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEU9746473.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     KADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            10136..13645
                     /gene="mfd"
                     /locus_tag="VW348_001597"
     CDS             10136..13645
                     /gene="mfd"
                     /locus_tag="VW348_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEU9746474.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERDLAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKELMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            13703..13969
                     /locus_tag="VW348_001598"
     CDS             13703..13969
                     /locus_tag="VW348_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEU9746475.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            13962..14330
                     /locus_tag="VW348_001599"
     CDS             13962..14330
                     /locus_tag="VW348_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEU9746476.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGVVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            14450..15718
                     /locus_tag="VW348_001600"
     CDS             14450..15718
                     /locus_tag="VW348_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEU9746477.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKISFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            15715..16992
                     /gene="tilS"
                     /locus_tag="VW348_001601"
     CDS             15715..16992
                     /gene="tilS"
                     /locus_tag="VW348_001601"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEU9746478.1"
                     /translation="MREQDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNIDVENLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ELIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            16996..17538
                     /gene="hpt"
                     /locus_tag="VW348_001602"
     CDS             16996..17538
                     /gene="hpt"
                     /locus_tag="VW348_001602"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEU9746479.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKEREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            17554..>19507
                     /gene="ftsH"
                     /locus_tag="VW348_001603"
     CDS             17554..>19507
                     /gene="ftsH"
                     /locus_tag="VW348_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEU9746480.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQNPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
BASE COUNT         6738 a         3129 c         3650 g         5990 t
ORIGIN      
        1 cacttttgag attttttctc taaaatatct tttaattttc taatttttaa tcttgaaata
       61 ggacaacgat ggtcttcata gaaaacaatt tctaagtttt ttcgatcaat ttctctgata
      121 ttgcctatat ttaccaaaaa tgacttgtga ggagaataaa atcgctgagc atgtttgtcc
      181 ttttcctgaa tatctgtcat ggtaccataa aactcttttg caaaattctt accaataatg
      241 cgcaatttat gagagactcc tgtcgtttca atatacaaaa tatcatggta aggaattttt
      301 aaatcatttc ccttgtaatt gtagtcgaaa taatctacaa catcttcatt ttcaagtaac
      361 atactcttcg tgtagaagat attttgctca attcgcttct taaacatctc atcgttgata
      421 tccttatcaa caaaatctag ggctgatatc tggtatttat aggtcagagt cgcaaactct
      481 gatcgactgg tgataaagac gataatagcg taaggattgt aatgacgaat gagttgagca
      541 acttcaaatc cctttttctc aattccatga atatcgatat ctaggaaata aagttgattt
      601 acttcatcat tttcaatgta ttcttcaaat tcacggactt ttcccgttgt cttgtatgat
      661 attggagtat tcgattcttt cgaaatttca tccaatattc tctctagtct cacttgatgt
      721 tcaataacat cttctaaaat taaaactttc attcaaattt cctcttaaat ctaatgattt
      781 gtctaaatgt actgccttcc atctctgttt ctaaaataat gttgttgtac ttatctagta
      841 gttctttcac attatttaat ccgactccgc gatttcttcc cttagtggag aatcctaagg
      901 caaatagatc tcctgaagga gtcatcgtca ttttacatga attctgaatc acaataactg
      961 tttcagtttc catcttaata actgctactt ccatctgctt tttatagcta tcagccgatc
     1021 cttcgacagc attgttcaat aaaacgctca tgatacgcac taaatccaat agttcaattg
     1081 gaagcttggt aatcgtatct tttacttcca gtgtaaactc tacaccatta tttcgagcat
     1141 agacaattga ctgagcaacc aaacttcgta aagctgaatc ttctatgttg ttcaaatcaa
     1201 agtaagtgta cttatctgaa cgtagtttat gatttgcttt gaccaaaact tcattgtaaa
     1261 ctctgtcaat ttcctgtaaa ttaccactgt caattgccat ctgcatgctg acaagcattc
     1321 cagcataatc atgtcgaaaa ccacggattt cattatacag accgacaatt tcatctgtgt
     1381 aattctgtaa atgtttctgt tcaaatttct tctgcttcaa agcaatctct ttctccattt
     1441 gaactttatg agaattcatt gcaaagaagg tcaaaaggag agagataaag acaatagatg
     1501 acaaaatact tccaaaacta ttcaaatgtt taatcgtact taccatatct gaaacgaaag
     1561 atacaatatg tagcaatagt aaagcaaaaa atactttttt caagaaagga taaaggtagt
     1621 ccttgtcaaa ataggctagt tccaaatgga aataataaat gatttttaat gtaacaaaat
     1681 aggtcaacac cgtcacaacg aaaaagaata ggccataata ctgtaaaaca aaattgtctc
     1741 ctgttataga agagaaagtt acggacagaa agttatgagt gctctcatat aaaagagata
     1801 gtagtaaact tagaaatagt cctctatccc tctcatactg tttcatccat cgaaaatagg
     1861 aatataggcc caaaggaaat aaaaatgttg caatccctaa cccatctaaa tatagaagat
     1921 agaagggaaa atcaagtact atttctgtta gtaatgtata agcaccaaaa aagaataatt
     1981 cttttctatt tatttgatct ttacaaatta aacggtaact atgactaata attaaaaaat
     2041 ataatatcaa atctactaat aagaaaaaat ccattctgct actcctttat cttcttctaa
     2101 agaaattaaa gaaattaaag atattaaagg acttttcatt cattttcctc atctccccac
     2161 cttgaatatt ttgcaagtct ttttccttca aagctacaaa ctgttccaat ttaactgtgt
     2221 ttttcataat aaaatctcct aaaatgtttt ttcttgtaag ctaacttaca aaaaccatta
     2281 tacaaaatgg aatttcgttt tagataaaat tctctcaact gtcatttttt tctcccaaag
     2341 tgtacttttt taagaaaaaa gccgggaaaa ttcccagctt tgctattata ttgatcccag
     2401 caggattcga acctgcgacc gttcgcttag aaggcgaatg ctctatccag ctgagctatg
     2461 agacctaaca caattattct accaaaaatt caattaaaag tcaattttct atttatggta
     2521 ggggaatccc tgctgaatcg taaaagcgcg atagatttgt tcaacaagaa ctagtctcat
     2581 taactgatga ggcaaggtta ggcgaccaaa actgacagaa agattggctc tattttttac
     2641 agatgatgat aatcctaaac ttcccccaat aataaaagta agagtagaaa atccttttat
     2701 agaagtttct tctaactgct tactaaattc ttctgagaag aaagttttcc cttcaatggc
     2761 taacacaata acgaaatcac ggtcagcaat ttttgataaa attctctgac cttctatttc
     2821 taaaatcttt tgattttctg attcactggc cttatctggt gttttttcat ctgataactc
     2881 aatcatttca aacttagcaa atctagaaat tcgttttgaa tactctgcga taccatcttt
     2941 taaatacttt tctttcagtt tcccaactgt tacaacttta attttcatga ctctattcta
     3001 acatattctc tattttttca catcttattc acaaaataaa aaatagattt caattaagaa
     3061 aatcacagtt tcaaaagagt tatccacagt ttgtgtaaaa cttttgtgtt taagttataa
     3121 ttaagctagt cagtttatac tttcagtaat tcaaacatat ggaggcaaat atgaaacatc
     3181 taaaaacatt ttacaaaaaa tggtttcaat tattagtcgt tatcgtcatt agctttttta
     3241 gtggagcctt gggtagtttt tcaataactc aactaactca aaaaagtagt gtaaacaact
     3301 ctaacaacaa tagtactatt acacaaactg cctataagaa cgaaaattca acaacacagg
     3361 ctgttaacaa agtaaaagat gctgttgttt ctgttattac ttattcggca aacagacaaa
     3421 atagcgtatt tggcaatgat gatactgaca cagattctca gcgaatctct agtgaaggat
     3481 ctggagttat ttataaaaag aatgataaag aagcttacat cgtcaccaac aatcacgtta
     3541 taaatggcgc cagcaaagta gatattcgat tgtcagatgg gactaaagta cctggagaaa
     3601 ttgtcggagc tgacactttc tctgatattg ctgtcgtcaa aatctcttca gaaaaagtga
     3661 caacagtagc tgagtttggt gattctagta agttaactgt aggagaaact gctattgcca
     3721 tcggtagccc gttaggttct gaatatgcaa atactgtcac tcaaggtatc gtatccagtc
     3781 tcaatagaaa tgtatcctta agatcggaag atggacaagc tatttctaca aaagccatcc
     3841 aaactgatac tgctattaac ccaggtaact ctggcggccc actgatcaat attcaagggc
     3901 aggttatcgg aattacctca agtaaaattg ctacaaatgg aggaacatct gtagaaggtc
     3961 ttggtttcgc aattcctgca aatgatgcta tcaatattat tgaacagtta gaaaaaaacg
     4021 gaaaagtgac gcgtccagct ttgggaatcc agatggttaa tttatctaat gtgagtacaa
     4081 gcgacatcag aagactcaat attccaagta atgttacatc tggtgtagtt gttcgttcgg
     4141 tacaaagtaa tatgcctgcc aatggtcacc ttgaaaaata cgatgtaatt acaaaagtag
     4201 atgacaaaga gattgcttca tcaacagact tacaaagtgc tctttacaac cattctatcg
     4261 gagacaccat taagataacc tactatcgta acgggaaaga agaaactacc tctatcaaac
     4321 ttaacaagag ttcaggtgat ttagaatctt aattgacatc tatgtaaaga aagctttaca
     4381 taagagaaaa gatgtgttag tgtagaatca tggaaaaatt tgaaatgatt tctatcacag
     4441 atatacaaaa aaatccctat caaccccgaa aagaatttga tagagaaaag ctagatgaac
     4501 tagcacagtc tatcaaagaa aatggggtca ttcaaccgat tattgttcgt caatctcctg
     4561 ttattggtta tgaaatcctt gcaggagaga gacgctatcg ggcttcactt ttagctggtc
     4621 tacggtctat cccagctgtt gttaaacaga tttcagacca agagatgatg gtccagtcca
     4681 ttattgaaaa tttacagaga gaaaatttaa acccaataga agaagcacgc gcctatgaat
     4741 ctctcgtaga gaaaggattc acccatgctg aaattgcaga taagatgggc aagtctcgtc
     4801 catatatcag caactccatt cgtttacttt ccttgccaga acagattctc tcagaagtag
     4861 aaaatggcaa actatcacaa gcccatgcgc gttccctagt tgggttaaat aaggaacaac
     4921 aagactattt ctttcaacgg attatagaag aagatatttc tgtaaggaag ttagaagctc
     4981 ttctgacaga gaaaaaacaa aagaaacagc aaaaaactaa ttatttcata caaaatgaag
     5041 aaaaacagtt aagaaaacta ctcggattag atgtagaaat taaactatct aaaaaagaca
     5101 gtggaaaaat cattatttat ttttcaaatc aagaagaata tagtagaatt atcaacagcc
     5161 tgaaataagg ctgttctttt atttttttat ctcacaaggt tatccactat gtttttcgat
     5221 aaaaagctta ataaatcaat aatttcttct tttatcccca acctgtggat aaagtttagt
     5281 aacattgtgg attatttttc acagcttgtg gaaaattctt gctatctatg gtaaaatatc
     5341 tctagtatta aacttttaaa tagtaaagga ggaaaaagga ttgaaagaaa aacaattttg
     5401 gaatcgtata ttagaatttg cacaagaaag actgactcga tccatgtatg atttctatgc
     5461 tattcaagct gaactcatca aggtagagga aaatgttgcc actatatttc tacctcgctc
     5521 tgaaatggaa atggtctggg aaaaacaact aaaagatatt attgtagtag ctggttttga
     5581 aatttatgac gctgaaataa ctccccacta tattttcacc aaacctcaag atacgactag
     5641 ctcacaagtt gaagaagcta caaatttaac tctttatgac tatagtccaa agttagtatc
     5701 tattccttat tcagatacgg gattaaaaga aaagtatacc tttgataact ttattcaagg
     5761 ggatggaaat gtttgggctg tgtcagccgc tttagctgtc tctgaagatt tggctctgac
     5821 ctataaccct ctttttatct atggaggacc aggccttggt aagactcact tattaaacgc
     5881 tattggaaat gaaattctaa aaaatattcc taatgcgcgt gttaaatata tccctgccga
     5941 aagctttatt aatgactttc ttgatcacct aagacttggg gaaatggaaa agtttaaaaa
     6001 gacctatcgt agtcttgatc ttttgttaat cgatgatatc cagtcactca gcggaaaaaa
     6061 agtcgcaact caggaagaat ttttcaatac ctttaacgcc cttcatgaca agcaaaaaca
     6121 gattgtccta acgagtgatc gtagtccaaa acatctagaa gggctcgagg agaggcttgt
     6181 cacgcgtttt agttggggat tgacacaaac tatcacaccc cctgactttg aaacacgtat
     6241 tgccatttta caaagtaaaa cggaacattt aggctacaat ttccaaagtg atactctaga
     6301 atacctagct gggcaatttg attcaaatgt tcgagatctt gagggagcca tcaacgacat
     6361 cactttaatt gccagagtaa aaaaaatcaa ggatatcact attgatattg ctgcagaagc
     6421 cattagagcc cgcaaacaag atgttagcca aatgctcgtc atcccaattg ataaaatcca
     6481 aactgaagtt ggtaactttt atggtgttag tatcaaagaa atgaagggaa gtagacgcct
     6541 tcaaaatatt gttttggccc gtcaagtagc catgtattta tctagagaac taacagataa
     6601 tagtcttcca aaaattggga aggaatttgg gggaaaagat cataccacag tcattcatgc
     6661 ccatgccaaa ataaaatctt tgattgatca agacgataat ttacgtttag aaattgaatc
     6721 aatcaaaaag aaaatcaaat aatttgtgga taacttttag ttttttatct tttttatcca
     6781 cattttttaa acaagctaaa aaacttgata ggacttgttt aaaggctgtt ttccacagat
     6841 ttcacagact ctattattac tattatcttt ctaatactaa aaataaataa aggagaatcc
     6901 atgattcatt tttcaattaa taaaaattta tttctacaag cattaaatac tactaagaga
     6961 gctattagtt ctaaaaatgc cattcctatt ttatcaacaa taaaaattga cgtgaccaat
     7021 gaaggtatta ctttaattgg ttcaaatggt caaatttcaa ttgaaaattt tatttctcaa
     7081 aaaaatgaag atgctggttt gttaattact tctttaggtt cgatccttct tgaagcttct
     7141 ttctttatca atgtagtatc tagtttacct gatgtaactc ttgattttaa agaaattgaa
     7201 caaaatcaaa ttgttttaac cagtggcaaa tcagaaatta ccctaaaagg aaaagatagc
     7261 gaacaatatc cacgaatcca agaaatttca gcaagcactc ctttaatact tgaaacaaaa
     7321 ttactcaaga aaattattaa tgaaacagcc tttgctgcaa gtacacaaga gagtcgtccg
     7381 attttaacag gtgtccactt cgtattgagt caacacaaag agttaaaaac agttgcaaca
     7441 gactctcatc gcctaagcca gaaaaaattg actcttgaaa aaaatagtga tgattttgat
     7501 gtcgtaattc ctagccgttc tctacgcgaa ttttcagcgg tatttacaga tgatatcgaa
     7561 actgtagaga ttttctttgc caataaccaa atcctcttta gaagcgaaaa tattagcttc
     7621 tatactcgtc tcctagaagg aaactatcct gatacagatc gcttgattcc aacagacttt
     7681 aacactacta ttacttttaa tgtggtaaac ttacgccagt caatggagcg tgcccgtctt
     7741 ttatcaagtg cgactcaaaa tggtactgtg aaacttgaaa ttaaggatgg ggttgttagc
     7801 gcccatgttc actctccaga agttggtaaa gtaaacgaag aaatcgatac tgatcaggtt
     7861 actggtgaag atttgaccat tagtttcaac ccaacttact tgattgattc tcttaaagct
     7921 ttaaatagcg aaaaggtgac cattagcttt atctcagctg ttcgtccatt tactcttgtg
     7981 ccagcagata ctgacgaaga cttcatgcag ctcattacac cagttcgtac aaattaagtg
     8041 aaagaggttg agcctggctc gcctctttta tgatataatc gaaaaagaaa aggagagtag
     8101 tatgtatcaa gttggaaatt ttgttgagat gaaaaaatca cacgcttgta caatcaagtc
     8161 gactggtaaa aaggctaatc gttgggaaat tacacgtgta ggagcagata tcaaaataaa
     8221 atgcagtaat tgtgagcatg ttgtcatgat ggggcgatat gattttgagc gaaaaatgaa
     8281 taaaattatt gactgagaac ccttagttag agggttagca ctttatccct ttttgtgtta
     8341 taatattagg gattgaaatg aaaacggaga atgagaaata tggctttgac agcaggtatc
     8401 gttggtttgc caaacgttgg taaatcaaca ctatttaatg caattacaaa agcaggagca
     8461 gaggcagcaa actacccatt tgcgactatt gatccaaatg ttggaatggt ggaagttcca
     8521 gatgaacgcc tacaaaaact aactgaaatg ataactccta aaaagacagt tcccacaaca
     8581 tttgaattta cggatattgc agggattgta aaaggagctt caaaaggaga agggctaggg
     8641 aataaattct tggccaatat tcgtgaagta gatgcgattg ttcacgtagt tcgtgctttt
     8701 gatgatgaaa atgtgatgcg cgagcaagga cgtgaagacg cctttgtgga tccacttgca
     8761 gatattgaca ccattaacct agaattgatt cttgcagact tagaatcagt caataaacga
     8821 tatgcgcgtg tagaaaagat ggcacgtacg caaaaagata aagaatcagt agcagaattc
     8881 aatgttcttc aaaagattaa accagtccta gaagacggga aatcagctcg taccattgaa
     8941 tttacagatg aggaacaaaa ggttgtcaaa ggtcttttcc ttttgacgac taaaccagtt
     9001 ctttatgtag ctaatgtgga cgaggatgtg gtttcagaac ctgactctat cgactatgtc
     9061 aaacaaattc gtgaatttgc agcgacagaa aatgctgaag tagtcgttat ttctgcgcgt
     9121 gctgaggaag aaatttctga attggatgat gaagataaaa aagagtttct tgaagccatt
     9181 ggtttgatag aatcaggtgt agataagttg acgcgtgcag cttaccactt gcttggattg
     9241 ggaacttact tcacagctgg tgaaaaagaa gttcgcgctt ggactttcaa acgtggtatg
     9301 aaggctcctc aagcagctgg tattatccac tcagactttg aaaaaggctt tattcgtgca
     9361 gtaaccatgt catatgagga tctagtgaaa tacgaatctg aaaaggccgt aaaagaagct
     9421 ggacgcttgc gtgaagaagg aaaagaatat atcgttcaag atggcgatat catggaattc
     9481 cgctttaatg tctaaaaatt aataaatggt gtcaattagg ttggaaaaaa attccaaccc
     9541 ttttggcttt tgaaaggaaa aataaatgac caaattactt gtaggcttgg gaaatccagg
     9601 ggataaatat tttgaaacaa aacacaatgt tggttttatg ttgattgatc aactagcgaa
     9661 gaaacagaat gtcactttta cacacgataa gatatttaaa gctgacctag catccttttt
     9721 cctaaatgga gaaaaaattt atctggttaa accaacgacc tttatgaatg aaagtggaaa
     9781 agcagttcat gctttattaa cttactatgg tttggatatt gacgatttac ttatcattta
     9841 cgatgatctt gacatggaag ttgggaaaat tcgtttaaga gcaaaaggct cagcaggtgg
     9901 tcataatggt atcaagtcta ttattcaaca tataggaact caggtcttta accgtgttaa
     9961 gattggaatt ggaagaccta aaaatggtat gtcagttgtt catcatgttt tgagtaagtt
    10021 tgacagggat gattatatcg gtattttaca gtctgttgac aaagttgacg attctgtaaa
    10081 ctactattta caagagaaaa attttgagaa aacaatgcag aggtataacg gataaatggt
    10141 gaccttatta gatttattct cagaaaatga tcagattaaa aaatggcatc aaaatttaac
    10201 tgataagaaa agacaactaa tacttggttt atcaacatct actaaggctc ttgcaattgc
    10261 aagcagttta gaaaaagaag ataggattgt gttattgacg tcaacttatg gagaagcaga
    10321 aggacttgtt agtgatctta tatctatctt gggtgaggaa ctcgtctatc catttttggt
    10381 agatgatgct cctatggtgg agtttttgat gtcttcacag gaaaaaatta tttcacgggt
    10441 tgaagccttg cgttttttga ctgattcatc taagaaaggg attttagttt gtaatatcgc
    10501 agcaagtcga ttgattttac cgtctcccaa tgcattcaaa gatagtattg taaaaatctc
    10561 agttggtgaa gaatatgatc aacacgcgtt tatccatcag ttaaaggaaa atggctatcg
    10621 aaaagttact caagtacaaa ctcagggcga atttagtctt cgaggagata ttttagatat
    10681 ttttgaaata tcccagttag aaccttgtcg aattgagttt tttggtgatg aaattgatgg
    10741 tatcaggtca tttgaagtag aaacacaatt atcgaaagaa aataagacag aactcactat
    10801 ctttccagct agtgatatgc ttttgagaga aaaggattat caacgaggac agtcagcttt
    10861 agaaaaacaa atttcaaaaa ctttatcacc tattttgaaa tcatacctag aagaaattct
    10921 ttcaagtttt caccaaaaac aaagtcatgc agactctcgg aagtttttat ctttgtgcta
    10981 tgataagaca tggactgtct ttgattatat tgaaaaagat actccaatat tctttgatga
    11041 ttatcaaaaa ttgatgaatc agtatgaagt ctttgaaaga gacttagcgc agtactttac
    11101 agaagaatta cagaatagta aagcattttc tgatatgcag tatttttctg atattgaaca
    11161 aatctataaa aaacaaagtc cagtgacctt tttctctaat cttcaaaagg gtttaggaaa
    11221 tctcaaattt gacaaaattt atcaattcaa tcaatatcct atgcaggaat ttttcaatca
    11281 gttttctttt ctaaaagaag aaattgaacg atataaaaaa atggattaca ccattattct
    11341 gcagtctagc aattcaatgg gaagtaaaac attggaggat atgttagagg aatatcagat
    11401 taaattggat tctagagata agacaaatat ctgtaaagaa tctgtaaact taatagaggg
    11461 taatctcaga catggttttc attttgtaga tgaaaagatt ttattgataa ctgaacatga
    11521 gatttttcaa aagaaattaa agcgtcgttt tcgaagacaa catgtttcaa atgcagagag
    11581 attaaaagat tacaatgaac ttgaaaaagg ggactatgtt gtccatcata tccatgggat
    11641 tggtcaatat ctaggaattg aaaccattga aatcaaggga attcatcgcg attatgtcag
    11701 tgtccaatac caaaatggtg atcaaatttc tatccccgtg gaacagattc atctactgtc
    11761 caaatatatt tcaagtgatg gtaaagctcc aaaactcaat aaattaaatg acggtcattt
    11821 taaaaaggcc aagcaaaagg ttaagaacca ggtagaggat atagctgatg atttaatcaa
    11881 actctactct gaacgtagtc agttgaaggg ttttgctttc tcagctgatg atgatgatca
    11941 agatgccttt gatgatgctt tcccttatgt tgaaacggat gatcaacttc gtagtattga
    12001 ggaaatcaaa agggatatgc aggcttctca gccaatggat cgacttttag ttggggatgt
    12061 tggttttgga aagactgaag ttgctatgcg tgcagccttt aaagcagtca atgatcacaa
    12121 acaggttgtc attctagttc cgacgacggt tttagcgcaa cagcactata cgaattttaa
    12181 ggaacgattc caaaattttg cagttaatgt tgatgtgttg agtcgcttta gaagtaaaaa
    12241 agagcagact gcaacacttg aaaaattgaa aaacggtcaa gtcgatattt tgattggaac
    12301 acatcgtgtt ttgtcaaaag atgttgtgtt tgctgatttg ggcttgatga ttattgatga
    12361 ggaacagcga tttggtgtca agcataagga aactttgaaa gaactgaaga aacaagtgga
    12421 tgtcctaacc ttgaccgcta cgccaatccc tcgtaccctc catatgtcta tgctgggaat
    12481 cagagatttg tctgttattg aaactccgcc gactaatcgc tatcctgttc agacctatgt
    12541 tttggaaaag aatgatagtg tcattcgtga tgctgtcttg cgtgaaatgg agcgtggagg
    12601 tcaagtttac tatctttaca acaaagttga cacaattgtt cagaaggttt cagaattaca
    12661 ggagttgatt ccggaggctt cgattggata tgttcatggt cgaatgagtg aagtccagtt
    12721 ggaaaatact ctattagact ttattgaggg acaatacgat atcttggtga cgactactat
    12781 tattgagaca ggggtggaca ttccaaatgc taatacttta tttattgaaa atgcggacca
    12841 tatgggcttg tcaaccttat atcagttaag aggaagagtc ggtcgtagta atcgtattgc
    12901 ttatgcttat ctcatgtatc gtccagaaaa atcaatcagt gaagtctctg aaaagagatt
    12961 agaagcgatt aaaggattta cagaattggg ctctggcttt aagattgcaa tgcgagatct
    13021 ttcgattcgt ggagcaggaa atcttttagg aaaatcccag tctggtttca ttgattctgt
    13081 tggttttgaa ttgtattcgc agttattaga ggaagctatt gctaaacgaa acggtaatgc
    13141 taacgctaac acaagaacca aagggaatgc tgagttgatt ttgcaaattg atgcctatct
    13201 tcctgatact tatatttctg atcaacgaca taagattgaa atttacaaga aaattcgtca
    13261 aattgacaac cgtgtcaatt atgaagagtt acaagaggag ttgatagacc gttttggaga
    13321 atacccagat gtagtagcct atcttttaga gattggtttg gtcaaatcat acttggacaa
    13381 ggtctttgtt caacgtgtgg aaagaaaaga taataaaatt acaattcaat ttgaaaaagt
    13441 cactcaacga ctgtttttag ctcaagatta ttttaaagct ttatccgtaa cgaacttaaa
    13501 agcaggcatc gctgagaata aggaattaat ggagcttgta tttgatgttc aaaataagaa
    13561 agattatgaa attttagaag gtctgctgat ttttggagaa agtttattag agataaaaga
    13621 gtctaaggaa gaaaattcca tttgatattt ttcttctata aaatagataa aaatggtaca
    13681 ataataaatt gaggtaataa ggatgagatt agataaatat ttaaaagtat cgcgaattat
    13741 caagcgtcgt acagtcgcaa aggaagtagc agataaaggt agaatcaagg ttaatggaat
    13801 cttggccaaa agttcaacgg acttgaaagt taatgaccaa gttgaaattc gctttggcaa
    13861 taagttgctg cttgtaaaag tactagagat gaaagatagt acaaaaaaag aagatgcagc
    13921 aggaatgtat gaaattatca gtgaaacacg ggtagaagaa aatgtctaaa aatattgtac
    13981 aattgaataa ttcttttatt caaaatgaat accaacgtcg tcgctacctg atgaaagaac
    14041 gacaaaaacg gaatcgtttt atgggagtgg tattgatttt gattatgcta ttatttatct
    14101 tgccaacttt taatttagcg cagagttatc agcaattact ccaaagacgt cagcaattag
    14161 cagacttgca aactcagtat caaactttga gtgatgaaaa ggataaggag acagcatttg
    14221 ctaccaagtt gaaagatgaa gattatgctg ctaaatatac acgagcgaag tactattatt
    14281 ctaagtcgag ggaaaaagtt tatacgattc ctgacttgct tcaaaggtga taaaatggaa
    14341 aatttattag acgtaataga gcaatttttg agtttgtcag atgaaaagct ggaagaattg
    14401 gctgataaaa atcaattatt gcgtttacaa gaagaaaagg aaaggaagaa tgcgtaaatt
    14461 cttaattatt ttgttgctac caagtttttt gaccatttca aaagtcgtta gcacagaaaa
    14521 agaagtcgtc tatacttcga aagaaattta ttacctttca caatctgact ttggtattta
    14581 ttttagagaa aaattaagtt ctcccatggt ttatggagag gttcctgttt atgcgaatga
    14641 agatttagta gtggaatctg ggaaattgac tcccaaaata agttttcaaa taaccgagtg
    14701 gcgcttaaat aaacaaggaa ttccagtatt taagctatca aatcatcaat ttatagctgc
    14761 ggacaaacga tttttatatg atcaatcaga ggtaactcca acaataaaaa aagtatggtt
    14821 agaatctgac tttaaactgt acaatagtcc ttatgattta aaagaagtga aatcatcctt
    14881 atcagcttat tcgcaagtat caatcgacaa gaccatgttt gtagaaggaa gagaatttct
    14941 acatattgat caggctggat gggtagctaa agaatcaact tctgaagaag ataatcggat
    15001 gagtaaagtt caagaaatgt tatctgaaaa atatcagaaa gattctttct ctatttatgt
    15061 taagcaactg actactggaa aagaagctgg tatcaatcaa gatgaaaaga tgtatgcagc
    15121 cagcgttttg aaactctcct atctctatta tacgcaagaa aaaataaatg agggtcttta
    15181 tcagttagat acgactgtaa aatacgtatc tgcagtcaat gattttccag gttcttataa
    15241 accagaggga agtggtagtc ttcctaaaaa agaagataat aaagaatatt ctttaaagga
    15301 tttaattacg aaagtatcaa aagaatctga taatgtagct cataatctat tgggatatta
    15361 catttcaaac caatctgatg ccacattcaa atccaaaatg tctgccatta tgggagatga
    15421 ttgggatcca aaagaaaaat tgatttcttc taagatggcc gggaagttta tggaagctat
    15481 ttataatcaa aatggatttg tgctagagtc tttgactaaa acagattttg atagtcagcg
    15541 aattgccaaa ggtgtttctg ttaaagtagc tcataaaatt ggagatgcgg atgaatttaa
    15601 gcatgatacg ggtgttgtct atgcagattc tccatttatt ctttctattt tcactaagaa
    15661 ttctgattat gatacgattt ctaagatagc caaggatgtt tatgaggttc taaaatgagg
    15721 gaacaagatt ttttaaatca ttttctcaag aagggatatt tcaaaaagca tgctaaggcg
    15781 gttctagctc tttctggtgg attagattct atgtttctat ttaaggtatt gtctacttat
    15841 caaaaagagt tagagattga attgattctg gctcatgtga atcataagca gagaattgaa
    15901 tcagattggg aagaaaagga attaaggaag ttggctgctg aagcagaact tcctatttat
    15961 atcagcaatt tttcaggaga attttcagaa gcgcgtgcac gaaattttcg ttatgatttt
    16021 tttcaagagg tcatgaaaaa gacaggtgcg acagctttag tcactgccca ccatgctgat
    16081 gatcaggtgg aaacgatttt gatgcgcttg attcgaggaa ctcgcttgcg ctatctatca
    16141 ggaattaagg agaagcaagt agtcggagag atagaaatca ttcgtccctt cttgcatttt
    16201 cagaaaaaag actttccatc aatttttcac tttgaagata catcaaatca ggagaatcat
    16261 tattttcgaa atcgtattcg aaactcttac ttaccagaat tggaaaaaga aaatcctcga
    16321 tttagggatg caatcttagg catcggcaat gaaattttag attatgattt ggcaatagct
    16381 gaattatcta acaatattga tgtggaaaat ttacagcagt tattttctta ctctgagtct
    16441 acacaaagag ttttacttca aacttatctg aatcgttttc cagatttgaa tcttacaaaa
    16501 gctcagtttg ctgaagttca gcagatttta aaatctaaaa gccagtatcg tcatccgatt
    16561 aaaaatggct atgaattgat aaaagagtac caacagtttc agatttgtaa aatcagtccg
    16621 caggctgatg aaaaggaaga tgaacttgtg ttacactatc aaaatcaggt agcttatcaa
    16681 ggatatttat tttcttttgg acttccatta gaaggtgaat taattcaaca aatacctgtt
    16741 tcacgtgaaa catccataca cattcgtcat cgaaaaacag gagatgtttt gattcaaaat
    16801 gggcatagaa aaaaactcag acgtttattt attgatttga aaatccctat ggaaaagaga
    16861 aactctgctc ttattattga gcaatttggt gaaattgtct caattttggg aattgcgacc
    16921 aataatttga gtaaaaaaac gaaaaatgat ataatgaaca ctgtacttta tatagaaaaa
    16981 atagataggt aaaaaatgtt agaaaacgat attaaaaaag tcctcgtttc acacgatgaa
    17041 attacagaag cagctaaaaa actaggtgct caattaacta aagactatgc aggaaaaaat
    17101 ccaatcttag ttgggatttt aaaaggatct attcctttta tggctgaatt ggtcaaacat
    17161 attgatacac atattgaaat ggacttcatg atggtttcta gctaccatgg tggaacagca
    17221 agtagtggtg ttatcaatat taaacaagat gtgactcaag atatcaaagg aagacatgtt
    17281 ctatttgtag aagatatcat tgatacaggt caaactttga agaatttgcg agatatgttt
    17341 aaagaaagag aagcagcttc tgttaaaatt gcaaccttgt tggataaacc agaaggacgt
    17401 gttgtagaaa ttgaggcaga ctatacctgc tttactatcc caaatgagtt tgtagtaggt
    17461 tatggtttag actacaaaga aaattatcgt aatcttcctt atattggagt attgaaagag
    17521 gaagtgtatt caaattagaa agaataatct ttaatgaaaa aacaaaataa tggtttaatt
    17581 aaaaatcctt ttctatggtt attatttatc tttttccttg tgacaggatt ccagtatttc
    17641 tattctggga ataactcagg aggaagtcag caaatcaact atactgagtt ggtacaagaa
    17701 attaccgatg gtaatgtaaa agaattaact taccaaccaa atggtagtgt tatcgaagtt
    17761 tctggtgtct ataaaaatcc taaaacaagt aaagaaggaa caggtattca gtttttcacg
    17821 ccatctgtta ctaaggtaga gaaatttacc agcactattc ttcctgcaga tactaccgta
    17881 tcagaattgc aaaaacttgc tactgaccat aaagcagaag taactgttaa gcatgaaagt
    17941 tcaagtggta tatggattaa tctactcgta tccattgtgc catttggaat tctattcttc
    18001 ttcctattct ctatgatggg aaatatggga ggaggcaatg gccgtaatcc aatgagtttt
    18061 ggacgtagta aggctaaagc agcaaataaa gaagatatta aagtaagatt ttcagatgtt
    18121 gctggagctg aggaagaaaa acaagaacta gttgaagttg ttgagttctt aaaagatcca
    18181 aaacgattca caaaacttgg agcccgtatt ccagcaggtg ttcttttgga gggacctccg
    18241 gggacaggta agactttgct tgctaaggca gtcgctggag aagcaggtgt tccattcttt
    18301 agtatctcag gttctgactt tgtagaaatg tttgtcggag ttggagctag tcgtgttcgc
    18361 tctctttttg aggatgccaa aaaagcagca ccagctatca tctttatcga tgaaattgat
    18421 gctgttggac gtcaacgtgg agttggtctc ggcggaggta atgacgaacg tgaacaaacc
    18481 ttgaaccaac ttttgattga gatggatggt tttgagggaa atgaagggat tatcgtcatc
    18541 gctgcgacaa accgttcaga tgtacttgat cctgcccttt tgcgtccagg acgttttgat
    18601 agaaaagtat tggttggccg tcctgatgtt aaaggtcgtg aagcaatctt gaaagttcac
    18661 gctaagaaca agcctttagc agaagatgtt gatttgaaat tagtggctca acaaactcca
    18721 ggctttgttg gtgctgattt agagaatgtc ttgaatgaag cagctttagt tgctgctcgt
    18781 cgcaataaat cgataattga tgcttcagat attgatgaag cagaagatag agttattgct
    18841 ggaccttcta agaaagataa gacagtttca caaaaagaac gagaattggt tgcttaccat
    18901 gaggcaggac ataccattgt tggtctagtc ttgtcgaatg ctcgcgttgt ccataaggtt
    18961 acaattgtac cacgcggccg tgcaggcgga tacatgattg cacttcctaa agaggatcaa
    19021 atgcttctat ctaaagaaga tatgaaagag caattggctg gcttaatggg tggacgtgta
    19081 gctgaagaaa ttatctttaa tgtccaaact acaggagctt caaacgactt tgaacaagcg
    19141 acacaaatgg cacgtgcaat ggttacagag tacggtatga gtgaaaaact tggcccagta
    19201 caatatgaag gaaaccatgc tatgtttggt gcacagaatc ctcaaaaatc aatttcagaa
    19261 caaacagctt atgaaattga tgaagaggtt cgttcattat taaatgaggc acgaaataaa
    19321 gctgctgaaa ttattcagtc aaatcgtgaa actcacaagt taattgcaga agcattattg
    19381 aaatacgaaa cattggatag tacacaaatt aaagctcttt acgaaacagg aaagatgcct
    19441 gaagcagtag aagaggaatc tcatgcacta tcctatgatg aagtaaagtc aaaaatgaat
    19501 gacgaaa
//
LOCUS       DAVKMJ010000039        18197 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000039 DAVKMJ010000000
VERSION     DAVKMJ010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18197
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.039"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(85..1020)
                     /locus_tag="VW348_001604"
     CDS             complement(85..1020)
                     /locus_tag="VW348_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEU9746481.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1017..1877)
                     /locus_tag="VW348_001605"
     CDS             complement(1017..1877)
                     /locus_tag="VW348_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEU9746482.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            1985..4147
                     /locus_tag="VW348_001606"
     CDS             1985..4147
                     /locus_tag="VW348_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEU9746483.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYFYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4239..5498
                     /locus_tag="VW348_001607"
     CDS             4239..5498
                     /locus_tag="VW348_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9746484.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5512..6378
                     /locus_tag="VW348_001608"
     CDS             5512..6378
                     /locus_tag="VW348_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEU9746485.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTRWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6392..7225
                     /locus_tag="VW348_001609"
     CDS             6392..7225
                     /locus_tag="VW348_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEU9746486.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKLTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7226..7306
                     /locus_tag="VW348_001610"
                     /pseudo
     CDS             7226..7306
                     /locus_tag="VW348_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            7583..9025
                     /gene="gtfA"
                     /locus_tag="VW348_001611"
     CDS             7583..9025
                     /gene="gtfA"
                     /locus_tag="VW348_001611"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEU9746487.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRSVVKALLNLFSFRNRSEAFDLEGTIEIETPTVHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9163..10356
                     /locus_tag="VW348_001612"
     CDS             9163..10356
                     /locus_tag="VW348_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEU9746488.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11043..13022
                     /locus_tag="VW348_001613"
     CDS             11043..13022
                     /locus_tag="VW348_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9746489.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13089..14585
                     /locus_tag="VW348_001614"
     CDS             13089..14585
                     /locus_tag="VW348_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9746490.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14585..15511
                     /locus_tag="VW348_001615"
     CDS             14585..15511
                     /locus_tag="VW348_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9746491.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15520..16587
                     /locus_tag="VW348_001616"
     CDS             15520..16587
                     /locus_tag="VW348_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9746492.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16598..17524
                     /locus_tag="VW348_001617"
     CDS             16598..17524
                     /locus_tag="VW348_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9746493.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQTELARYQKGLN"
     gene            complement(17599..>18197)
                     /locus_tag="VW348_001618"
     CDS             complement(17599..>18197)
                     /locus_tag="VW348_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9746494.1"
                     /translation="TVSLPNAKIVLDRFHIVQHLSRAMSRVRVQIMNQFHRKSHEHKA
                     IKHYWKLIQQDSRKLSDKQFYRPTFRMHLTNKEILNKLLSYSEDLKHHYQLYQLLLFH
                     FQNKEPEKFFELIEDNLKQVHPIFQTVFKTFLKDKEKIINALQLHYSNAKLEATNNLI
                     KLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT         5354 a         3227 c         3829 g         5787 t
ORIGIN      
        1 caataaaact tcagatccgt aaaacttaat tgaattacta atctgaagtt atttttatat
       61 cgtttatatt ataattgtgt tattttactt ccaactattg agagaaattt cgccactatt
      121 tagccagatt tcttttccgt tatcacattg aactaaaagt tttccatttt ctgagatgtc
      181 tttagcaagt cccttgtagt ctttttgctc tagtgtgaaa gtgacttctt ttcctagaat
      241 gaatgactgt tttttgtata ggtataatag ctcttctgct ggtgtttcga agaaagcacg
      301 ccagatttct atgatcaatt cattccttgt tataggagct gtagctttaa ataagctggc
      361 agctttttct tttaattcct gagggaagtc tttaatagtg aaattgatac ctactccaat
      421 aatgatatct gtgactaagc cagtttctac agaggtcatt gcttcagtaa ggattcctcc
      481 aattttatga ttgtttagat agatatcatt gacccatttt atgtcgacat ctattaaagt
      541 taggttctta atggctttgt agacagctcc agctacaagt agtgtgtagg atggtaattt
      601 gtcatagggg agatttggtt taagatggag tgtcatataa ataccacctt gtggtgagta
      661 gaaggaacgt tgaaaacggc ctcggcctgc tgtttgatag gaagctagat agagggtatt
      721 tgcttcatgg cctaaatcaa ttgcttcttt tgcatctagt tgtgttgatt ttgtttcggg
      781 tttaaagctg actttaattg gaagattttc ttctagaatc tctggaagaa taaggtcacc
      841 attcatcagt ttatatcctc tatttttgat actatcaatt tcaatgcctt cttgttctag
      901 tcgcttgatg gctttccaaa ttgctgttcg gcttagggat agtttttctg cgattttttc
      961 tccgctgata tagtcggttt ctttagatag gatttggtag acagcttggt aggatttcat
     1021 aatgttgcct ttcttactag ttggtattga gagtattctt ttcttgtatg acttggagtc
     1081 tgattaaagt attgtttata agctttcgaa aaatggagtg gatctgaaaa acctaccgag
     1141 tatgcaatta ccttgatgga ctcttgggta ttttcgagaa gttgtctagc tcggtgcatt
     1201 cgaacgtaga gtaggtattc tttgggtgat aaggtattaa attctttgaa tacgcttgat
     1261 aagtagcttc tgtgaacgga tagttctttt gctaaatctt gaattgtaag tgattgagga
     1321 tagtggctat caattaatcg tttgcattca agatagagtt ggtgggttga tgaaatattc
     1381 ttttttttct gattgggagc aatagttccc agatgaaaca tcagttcatg aagttgtccc
     1441 atgatatgga gttgagctaa ttcacttgat tttgtaatct gagcgaagcg gacaatgtct
     1501 gagatgagtt ttgcagtagt ctgggtatga caagtttcag attggatgag ataggattga
     1561 tcagaaattt gggaaagagc aaaataatca ggggctttcc ctccagtgat tcctaaccag
     1621 tagtaggccc aaggttcttt actatctgct tgataaaagg ttagttcctc tggttttaat
     1681 agaaagaaat ctccttcttt taaatcaaca attttaccct tgtaatgaaa ttttccttgt
     1741 cctttagtaa tgtaatgtag gacgtatgta tcacgaatgg ctggaccaaa agagtaatta
     1801 ggtgtgcatt cctcatatcc ataaaagctt agggcaaggt cgattgttcc agtctggtat
     1861 tctgaaaaaa ctaacatgtg ctacctccta cctaacattt taccatattc ttgagacatt
     1921 tttctatttt ggaaagcgat ttcaggtgat aaaatagagt caataaagtg atgaggtgaa
     1981 gtaaatggga gttaggatag agaataatct attttatgtt gagagtaaaa atctaagttt
     2041 gattattgaa aatcgaaatg gctacttact tttgaaacat ttaggaaaga ctattaagaa
     2101 ctataaaggt tccaatagtg tttatgaacg agaccatgcc ttttcaggaa atccaacagc
     2161 tactaatcga acctttagtt tagatactca acgtcaaatt tttggacaac atggcttagg
     2221 agattttagg aaaccaacca tacaggttca gcataatgta actgaagtaa cagactttcg
     2281 atttgtagaa gcaaagattt taaaaggtca gaatggtcca cagggcttac cttctccaca
     2341 tagcatggac gatacagaga ctcttgtctt aatgttagaa gattctaagg ctcaacttag
     2401 tctgactttg tattatacta cttttaataa tgatgcgact attgctagct acagtaaatt
     2461 agataataat agtaatcagg aagttgtcat ccataaagat ttttctttta tggctgattt
     2521 tccagctgca gattacgaaa tagtaactct gcagggtgct tatgctcgtg aaaagactgt
     2581 tagacgtcaa caggtagaac aaggaatctt ttcgattagt tcaaaccgag gtgcttctgg
     2641 tcatgctcaa acaccagctc ttctactatg cgaacaagga gtcacagagg atgctgggaa
     2701 tgtgtttgct attcaactaa tgtatagtgg caactttgaa gcttttgttc aaaaaaatca
     2761 attgaatgaa gttcgggtgg ctattggcat taatccagaa aacttttctt ggaagttagc
     2821 ccctgaggaa tactttgaaa caccggtagc tttagtgact cattcagatc agggattaac
     2881 tggtattagt catgaaagtc agaattttgt actgaagcac attatgctaa gtgaattttc
     2941 taaaaaagaa cgtccaattc taatcaataa ctgggaagct acttactttg actttcagag
     3001 agaaaaactg ttagagttag cagatgaagc taagaaagtt ggcattgaac tttttgtatt
     3061 agatgatggt tggtttggca atcgttttga tgataatcgt gctttaggtg attgggttgt
     3121 taatgaggaa aaactgggtg gaagtctaga aagtctgatt tcagctatcc atgaaagagg
     3181 tttgcagttt ggactttggt tagaacccga aatgatttct gtagatagtg atttgtatcg
     3241 tcaacatcct gactgggcta ttcaggttcc tggctatgag catacttatt ctcggaatca
     3301 attagtactt aatcttgcca atcctcaggt agtagaatac ttgaaaagtg tcttagatca
     3361 actcctatct tatcatgaga ttgattacat taaatgggat atgaaccgca atatcactaa
     3421 gctagggaat ggattaactt atctagagac acagatgcaa tctcatcagt acatgctggg
     3481 gctttatgaa ctcgtttctt atctgacaga gaagcacagc catattctct ttgagtcctg
     3541 ctctggtggt ggtggacgaa atgatcttgg tatgatacgc tatttcccac aagtctgggc
     3601 tagtgataat actgatgcca ttgcacgttt accaattcaa tacggttcat cctatttcta
     3661 tccaaccatt tctatggggg ctcatgtgtc agcagtaccg aatcatcaga tgggacgaat
     3721 gacaccatta gaaacacgtg gccatgtagc aatgatggga aatttgggct atgagcttga
     3781 tttgacaaat ttatcagatg aagagaaagc tacgattgct aatcaggtga acttgtataa
     3841 agaattacga ccagtagttc agttaggaca gcagtataga ctaattaatc ctgatactgc
     3901 atccaatgaa gcagctgtac aatttaatta cggaaatcaa acgattgtaa cctacgttcg
     3961 cgttttatct gttgtagaga ccatggaaac aactttaaaa ttaaaagatt tggatgaaga
     4021 gggactatat aaattacagg aaaatggcga agtttactca ggtgcagaac taatgtatgc
     4081 gggcttaact gttatcttat cccaaggaga ttttttgagt agacagtata tttttagaaa
     4141 actatgatat gtactgaccc caaaagttag atttattctg tctaactttt ggggtgcagt
     4201 tcaataaggg tgtataaatt tataaaggag gctttctaat ggaatggtat aaaaaaatcg
     4261 gacttcttgc aactacaggt ttagctttgt ttgggctcgg cgcttgctcc aactatggta
     4321 aatctgcgga tggcacagtg accatcgagt atttcaacca gaaaaaagaa atgaccaaaa
     4381 ccttggaaga aatcactcgt gattttgaga aggaaaaccc taagatcaag gtcaaagtcg
     4441 tcaatgtacc aaatgctggt gaagtattga agacacgcgt tctcgcagga gatgtgcctg
     4501 atgtggtcaa tatttaccca cagtccattg aactgcaaga atgggcaaaa gcaggtgttt
     4561 ttgaagattt gagcaacaaa gactacctga aacgcgtgaa aaatggctac gctgaaaaat
     4621 atgctgtaaa cgaaaaagtt tacaacgttc cttttacagc taatgcttat ggaatttact
     4681 acaacaaaga taaattcgaa gaactgggct tgaaggttcc tgaaacctgg gatgaatttg
     4741 aacagttagt caaagatatc gttgctaaag gacaaacacc atttggaatt gcaggtgcag
     4801 atgcttggac actcaatggt tacaatcaat tagcctttgc gacagcaaca ggtggaggaa
     4861 aagaagcaaa tcaatacctt cgttattctc aaccaaatgc cattaaattg tcggatccga
     4921 ttatgaaaga tgatatcaag gtcatggaca tccttcgcat caatggctct aagcaaaaga
     4981 actgggaagg tgctggctat accgatgtta tcggagcctt cgcacgtggg gatgtcctca
     5041 tgacaccaaa tgggtcttgg gcgatcacag cgattaatga acaaaaaccg aactttaaga
     5101 ttgggacctt catgattcca ggaaaagaaa aaggacaaag cttaaccgtt ggtgcgggag
     5161 acttggcatg gtctatctca gccaccacca aacatccaaa agaagccaat gcctttgtgg
     5221 aatatatgac ccgtccagaa gtcatgcaaa aatactacga tgtggacgga tctccaacag
     5281 cgatcgaagg ggtcaaacaa gcaggagaag attcaccgct tgctggtatg accgaatatg
     5341 cctttacgga tcgtcacttg gtctggttgc aacaatactg gaccagtgaa gcagacttcc
     5401 ataccttgac catgaactat gtcttgaccg gtgataaaca aggcatggtc aatgatttga
     5461 atgccttctt taacccgatg aaagcggatg tggattagga gtagagagac tatgaaaaaa
     5521 gtattacaaa aatattgggc atgggctttt gtggtcatcc ccctcttgtt acaagcaatt
     5581 ttcttctatg tgccgatgtt tcaaggagcc ttttacagtt ttaccaactg gacaggattg
     5641 acttacaact acaaatttgt cggcttaaac aactttaagc tcctcttcat ggatccaaaa
     5701 ttcatgaatg cgattggctt taccgcaatc attacgattg ccatggtggt tggtgagatt
     5761 gcactcggga tcttcattgc gcgtgtcttg aactctaaaa tcaaaggcca aaccttcttc
     5821 cgtgcttggt tcttcttccc agctgtttta tctggtttga cagtggcttt gatcttcaag
     5881 caagtcttca actacggtct tccagcgatt gggaatgccc ttcatattga atttctccaa
     5941 accagtcttt tagggactag gtggggagca atctttgcgg ctgtctttgt ccttctttgg
     6001 caaggggtgg ctatgcccat catcatcttc ctagctggtt tgcaatctat tccaactgag
     6061 attacagagg cagcaaggat tgatggtgcg actagcaagc aagttttctg gaacattgaa
     6121 ttgccttact tgctaccaag tgtctctata gtctttatcc tagccctaaa aggtgggctg
     6181 actgcctttg accaagtctt tgccatgacc ggtggtggtc caaacaatgc cacaacctca
     6241 cttgggctct tggtttataa ctatgccttt aaaaacaacc aattcggtta tgccaatgcc
     6301 attgccgtaa tcttgttctt cttaattgta gtgatttcga tcatccaatt gagagtatct
     6361 aagaaatttg aaatttaaga ggagaagcat gatgaaacaa gatgaaagaa aagccctgat
     6421 tggcaaatac attctattga ttctaggatc ggttctgatt ttagtgccgc tccttgctac
     6481 cctctttagt tccttcaaac tcactaagga tattgtagat aatttctttg gctttccaac
     6541 caacttcaca tgggacaact ttagccgtct cttagctgat gggattggag gctattattg
     6601 gaactctgtc gtcatcactg tcttgtcttt acttgcagta atgatcttta tccctatggc
     6661 agcctactcc atcgctcgca atatgagtaa aagaaaagcc tttaccatca tgtataccct
     6721 cttaatcctc ggaatcttcg tacctttcca agtcatcatg attccgatta cggttatgat
     6781 gagtaaactc ggtttggcta atacctttgg tttgatcttg ctctacttga cctatgcgat
     6841 tccacagacc ctctttctct atgttggcta tatcaaaatc tcgattccag aaagtctgga
     6901 tgaagcagca gagatcgatg gggctaatca atttacaacc tatttccgca tcatcttccc
     6961 aatgatgaaa ccgatgcatg cgacaaccat gatcatcaat gccctttggt tctggaatga
     7021 cttcatgttg ccactccttg tcttgaaccg ggattccaaa atgtggactc tgcctttgtt
     7081 ccaatacaac tacgcaggcc aatatttcaa cgactacgga ccaagctttg cctcttacgt
     7141 ggtcggcatt atcagtatca ccattgtcta tctcttcttc caacgccata tcatttcagg
     7201 aatgagcaac ggggcagtga agtaatactc aatgaaaatc aaagagcaaa ctaggaagct
     7261 agccgcaggt tgctcaaaac actgttttga ggttgtggat gaaactgacg aagtcagtaa
     7321 ccatacctac ggtaaggtga agctgacgtg gtttgaagag attttcgaat agtataagaa
     7381 gagctcatgg aatctatagt ctttgacaca gaggaagagt tcagcttgtt gataattcta
     7441 tgtagaaaac aagaaagtag tactttgttt atcacagtct atattagtac gagtttgatg
     7501 ataaatagag atttaaaatg aattttattt atgaagccag atcatatgag acttggcttc
     7561 aattagaaaa aggagagtaa tgatgccaat tcaaaataaa accatgttga ttacctattc
     7621 tgatagcctt ggaaataatc ttaaagactt atatgataat ttggaagagc attttggaga
     7681 tgctattgga ggagttcacc ttttaccatt tttcccatca acaggtgatc gtggatttgc
     7741 gccagttgac tacgacgaag tggactcagc ttttggtgat tgggaggatg ttaagcgttt
     7801 aggtgagaga tattatctta tgtttgattt tatgattaat catatttctc gtcaatccaa
     7861 gtattataag gactatcaag aaaaacatga agccagtgaa tttaaagatc tctttttaaa
     7921 ctgggataag ttttggccag aaaaccgtcc gacacagtct gatgtagatt taatttacaa
     7981 gcgtaaggat cgtgcaccaa agcaagagat tgtgtttgaa gatggttcag tggaacattt
     8041 gtggaatacc tttggtgagg agcagattga tcttgatgtg accaaagaag taactatgga
     8101 atttatccgt aagaccattc agcacttggc aagtaatggg tgtgatttga ttcgtctaga
     8161 tgcctttgct tatgcagtga agaaattgga tactaatgat ttctttgtgg aaccagatat
     8221 ttgggattta ttggacaaag ttcgagatat cgctgctgag tatgggacag agcttttacc
     8281 tgagattcat gaacactatt cgattcagtt taaaatagca gaccatgatt actatgttta
     8341 tgattttgct cttccaatgg tgacacttta tactctttac agttccagaa cagagcgttt
     8401 ggctaagtgg ttaaagatga gcccgatgaa gcaatttacg acgctagata cccatgatgg
     8461 gattggagta gtagatgtca aggatatcct gaccgatgag gagattgact atgcttcaaa
     8521 tgaactctat aaggttggag ccaatgtcaa acgtaagtac tctagtgccg agtataacaa
     8581 cttagatatc taccaaatca attcaaccta ctattcagcg cttggagatg atgatgtcaa
     8641 gtattttctc gctcgtctaa ttcaagcttt tgccccaggt attcctcagg tttactatgt
     8701 gggtctatta gcaggcaaga atgacttgaa attattagaa gaaactaaag aaggtcgaaa
     8761 tattaatcgt cattactata gcaacgagga aatagcaaaa gaagtgcaac gatctgttgt
     8821 gaaggccctt ctcaatctat tttctttccg taaccgttca gaagcctttg atctagaagg
     8881 gactattgag atagagacac caacagttca cagcattgta atcaaacgtc aaaataaaga
     8941 taagtccgta acagcagtag cagaaattga tttgcaaaat cagacttatc gggtaattga
     9001 gaatggagtt gaagtaacat tttgaagcct tgatatggtg gataaaatag ggtttttatt
     9061 ttggaaaacg tttcctttgt tttcaaattg ctaaaaaagt ggtacaatat aggatagctt
     9121 actattatct gaatcagctg atttggagag aaaggattca ttttgaaatc aataggcttt
     9181 attgaaaagc tgaaggggtt gtctagtaaa gagctgattt tattgggaat tatcctaagt
     9241 atctttttac ccttttatct ttttgtagtt gtactctgtt tatatattat cagtttgatt
     9301 tttacaggag acatgaaaag tattcttcag aaaatggggg agcatccgat gctgcttctt
     9361 tttcttagct atagtactgt tatatccatt cttgcacaaa attggatggg tcttgtggct
     9421 tcagtaggaa tgtttctatt tactattttc tttttgcact atcagtcgat tttatcccat
     9481 aaattctttc gattgatttt gcagttcgtc ttgtttggta gtgtcttgtc agctgctttt
     9541 gccagtttag aacatttcca aattgtgaag aaatttaact atgcttttct ttcacccaat
     9601 atgcaggtgt ggcatcagaa ccgggcagaa gtgactttct ttaatcctaa ttattatgga
     9661 attatttgtt gtttctgtat tatgattgct ttctatctgt ttacaacgac caagttgaat
     9721 tggttgaaag tattctgtgt gattgcaggc tttgttaatc tctttggttt gaactttact
     9781 caaaatcgaa ctgcctttcc tgctattatc gctggagcaa ttatctatct ctttacgact
     9841 attaaaaact ggaaggcctt ttggcttagt attggggtct tcgcgattgg tttgagtttc
     9901 ctcttttcta gtgatttggg agttcgaatg ggtactttag actcttctat ggaagaacgc
     9961 atttctatct gggatgctgg gatggccttg tttaagcaaa atcctttttg gggtgaaggg
    10021 ccattgacct atatgcactc ttatcctcgg atacatgctc cttatcatga acatgcccac
    10081 agtctttata ttgatacgat tctgagttac ggaattgtgg gtaccatttt attagttttg
    10141 tcttctgttg ctcctgttcg cttgatgatg gatatgagtc aggagtcggg gaaacgtccg
    10201 attatcggcc tttatctatc tttccttaca gtggttgctg tgcacggaat ttttgacttg
    10261 gctctcttct ggattcagtc aggctttatt ttcttgctag ttatgtgcag tattccattg
    10321 gagcatcgaa tgttggtatc ggacatgacg gattaagttt tataagtttg aaatcttcta
    10381 ccttgggtag gagatttttt tatacgatgg gcatgtcgtg catctgaggt gtaagtcctc
    10441 tgtagggatc cactaccggt gaatacaata gcgctcccca agcctgacta tcgtgaggta
    10501 gcggattaaa atggtctggg gatagatcgt tttaagtctg acgcaggaaa taagaattgt
    10561 cagagaaagc aatagtgaaa tcgtaggcta tgaatagaaa cgtgatagcg aggagcatat
    10621 agtggataag gtagcgagaa attttaaagt ataaaagata gtcttaatct atatatgtaa
    10681 atcacaaaag taattgaatt cggaataagg ttggtgtgaa aagacatagt aaactgaatc
    10741 ttgaatacta gaatgatact tctacaatat tgttataatt taatttgaat tccaaaatca
    10801 cattgttccg tccgtatttc attttactgt atgtcttcct aaactccaaa gtttctgcgt
    10861 caaatttcct attttcactg tagtctttga cacttcgaac gacaatttga atcatatatt
    10921 caaaaaaaaa tgaaaaattt gtgccaacaa gcctaaatat tctgaaaatt tgtttgattt
    10981 ttaatggata atgtgatata atggttgtca atctataatt cacataaaca gaggagtaga
    11041 aaatgaaaaa aaatcgtgta tttgctacag caggtcttgt tttattagca gcaggtgtac
    11101 ttgcagcatg cagttcttca aaatcatctg attcatcagc ccctaaagct tatggctatg
    11161 tttatacagc agacccagaa accttggact acctgatttc aagtaaaaat agtacaacag
    11221 tagtgacttc aaatgggatt gatggtttat tcactaacga taattacggt aatcttgctc
    11281 ctgcagttgc agaggattgg gaagtctcta aggatggttt gacctacact tataagattc
    11341 gtaaaggggt taaatggttt acctctgatg gagaagaata tgcagaggtg acggctaaag
    11401 atttcgtgaa cggtttaaaa cacgcagcag ataaaaaatc agaagctatg tatttagctg
    11461 aaaattcggt taaaggcttg gcagattatc tatcaggaac ttcaacagat ttttcaacag
    11521 ttggtgtcaa ggcggttgat gattatacgt tacaatacac tttgaaccag cctgaaccgt
    11581 tctggaactc taagttgacc tattctattt tctggcctct gaatgaagaa ttcgaaacat
    11641 caaaaggaag cgattttgct aaaccaacag atccgacatc cttgctttat aatggtccat
    11701 tcttgttgaa agggttgact gcaaaatctt ctgtagagtt tgtaaaaaat gagcaatatt
    11761 gggataaaga aaatgtccac ctagatacta tcaatctagc ttactatgat ggatcagatc
    11821 aggagtcgct agagcgtaac ttcactagtg gagcttatag ttatgcccgt ctttacccta
    11881 ccagctccaa ctattctaag gttgcagaag aatacaagga caatatctat tacacacaat
    11941 caggctctgg gattgctggt ctgggtgtga atattgatcg ccaaagttac aactatactt
    12001 ctaaaactac agattcagag aaagtagcta ctaagaaggc attgcttaac aaagatttcc
    12061 gtcaagcctt gaattttgct cttgatcgct cagcttactc agctcaaatc aatggtaaag
    12121 atggagcagc tttagcagtt cgtaatttat ttgtaaaacc agactttgtt tcagctggtg
    12181 agaagacctt tggtgattta gtcgctgctc aacttcctgc ttatggtgat gagtggaaag
    12241 gtgtgaattt agctgatggg caggatggtt tattcaatgc tgacaaggcc aaggcagagt
    12301 ttgcgaaagc taagaaagct ttagaagcag acggcgttca gtttcctatt catctggacg
    12361 ttccagtaga ccaagcatca aaaaactaca tatctcgtat tcagtccttt aaacaatctg
    12421 tagaaacagt tcttggtgtt gaaaatgtcg ttgttgatat tcaacaaatg acaagtgatg
    12481 aattccttaa tattacttac tatgctgcca atgcttcatc tgaggattgg gatgtatcag
    12541 gaggagtttc atgggggcca gactatcaag acccatctac ttacctggat attttaaaaa
    12601 caactagcag tgaaactaca aaaacatatt taggatttga taatccaaat agcccttcag
    12661 tagttcaagt tggtttgaaa gaatacgata aattagttga tgaagctgcc aaagagacaa
    12721 gcgacttgaa tgtccgttat gaaaaatatg cagcggctca agcatggttg acagatagtt
    12781 cactctttat tcctgctatg gcttcttctg gtgcagcacc agtgctttca cgaattgttc
    12841 catttactgg agcttctgcg caaacaggct ctaaggggtc agatgtttac ttcaaatatt
    12901 tgaaattaca agataaagtg gtgactaagg aagagtatga aaaagctcgt gaaaaatggt
    12961 tgaaagaaaa agctgaatca aatgagaaag ctcaaaaaga attggcaagt catgtgaagt
    13021 aaataatttc taatagaact ttctctccat gaggagaagg ttcttttggg atttttaaag
    13081 gaaataatat gaaaaaatat atttttatgc gtgttttgcg gtcattggtt tcgattttct
    13141 tagtaacgac tttgacctac acgattatct ataccttggt tcctcgaaaa ttgattttca
    13201 agcaggatcc taactataat aaaattgcga caacggctga taaacgtgat aactatgaaa
    13261 atactgtgtt tgagcgtatg ggctacattg agtattacga tactaaagag ttgcaagaaa
    13321 aggcaagtag catggattct tctgtaacag tagaagcaaa tgcgaccaat aaagctattt
    13381 atgaaaagta catcaatcaa ttaggtcatg gttggacttt gggagaattt actgaaagtg
    13441 gtcaattcta tgctactcgt gaaattccaa tttttgaacg tgtttttcac ttctatgcta
    13501 acttgattga cattgaccat acaaataaaa tccaagaccc tgaaaatcca gacttgaaac
    13561 gctaccttcg ttttgaaaat gatccagcta tcggatggtc attggtcggt tcaggaacta
    13621 aacataaata tctcttgtac tttaacagtc agttcccatt tgttcatcaa aactttgtga
    13681 acttgaattt aggtgactct tacccaacct atgctaatac accagttctt caggttatta
    13741 ctcaaggtca aggacaaacc aaaactgccc aagttcagtt cccaacaggt aagaaaacgt
    13801 cttctgtaaa tatttactca agaacctaca agtcacctag tcaggctgac tctcgtgaag
    13861 tagctagcta tgggaaagat gatccttata cagcgactga aagtaattac caatatccat
    13921 ctatgattgt cagctctgct attactggtt tgattggttt ggttcttgcc tatgctcttg
    13981 ccgtgccact tggttcagcc atggctcgtt tcaagaacac ttggattgat agcctctcaa
    14041 cagggacttt gaccttcttg cttgctcttc caacgattgc cttggtttac atcgttcgat
    14101 tgattggatc atctattgcc cttccagatt cattccctat cttgggagct ggagattggc
    14161 gttcttacgt tttaccagca gtcatccttg gtttattggg tgctcctgtt acagccattt
    14221 ggattcgtcg ttacatgatt gacttgcaat ctcaagactt tgttcgtttc gctcgtgcaa
    14281 aaggtttgtc tgaaaaagaa atttcaaaca aacacatctt taaaaatgcc atggttccgc
    14341 tggtttcagg aattcctggt gccattattg gggttatcgg tggtgcaacc cttactgaaa
    14401 cagtcttcgc cttcccaggt atgggtaaaa tgttgattga ctctgtaaaa gcatctaata
    14461 actctatggt cgttggtctt gtcttcatct ttacatgtat ttctatcttc tcacgtcttt
    14521 tgggagatat ttggatgact attattgacc cacgtattaa attgactgag aaaggaggca
    14581 aataatgtct acaatcgata aagaaaaatt tcagtttgta aaacgtgacg attttgcctc
    14641 tgaaactatt gatgcgccag catattctta ctggaaatca gtgtttaaac aatttatgaa
    14701 gaaaaaatca actgtagtca tgttgggaat cttggtagcc atcattttga taagtttcat
    14761 ctacccaatg ttttctaagt ttgatttcaa tgatgtcagc aaggtaaacg actttagtgt
    14821 tcgttatatc aagccaaatg cggagcattg gttcggtact gacagtaacg gtaaatcgct
    14881 ctttgacggt gtctggttcg gagctcgtaa ctccatcctc atttctgtga ttgcgacagt
    14941 gattaacttg gttatcggtg tttttgtcgg tggtatttgg ggtatttcaa aatcagttga
    15001 ccgtgtcatg atggaagttt acaacgtcat ctcaaacatc ccacctcttt tgattgttat
    15061 tgtcttgact tactcaatcg gagctggatt ctggaatctg atttttgcca tgagcgtaac
    15121 aacatggatt ggtattgcct tcatgattcg tgtgcaaatc ttgcgctatc gtgacttgga
    15181 atacaacttg gcgtcacgta ctttgggaac accaaccttg aagattgttg ccaaaaatat
    15241 catgcctcaa ttggtatctg ttattgtgac aaccatgact caaatgcttc caagctttat
    15301 ctcatacgaa gccttcttgt ctttcttcgg tcttggatta ccgattacag tgccaagttt
    15361 gggtcgtttg atttcggatt attcacaaaa cgtaacaacc aatgcttact tgttctggat
    15421 tccattgaca acccttgtct tggtatcctt gtcccttttc gtagttggtc aaaacttagc
    15481 ggatgctagt gatccacgta cacatagata ggagtagaaa tgacaaaaga aaaaaatgta
    15541 attttgactg ctcgcgatat tgtcgtggaa tttgacgttc gtgacaaagt attgacagcc
    15601 attcgcggcg tttcccttga actagtcgaa ggagaagtat tagccttggt aggtgagtca
    15661 ggatcaggta aatctgtttt gacaaagacc ttcacaggta tgctcgaaga aaatggtcgt
    15721 attgcccaag gtagtattga ctaccgtggt caggacttga cagctttatc ttctcacaag
    15781 gattgggaac aaattcgtgg tgctaagatt gcgactatct tccaggaccc aatgactagt
    15841 ttggacccca ttaaaacaat tggtagtcag attacagaag ttattgtaaa acaccaagga
    15901 aaaacagcta aagaagcgaa agaattggcc attgactaca tgaataaggt tggcattcca
    15961 gacgcagata gacgttttaa tgaataccca ttccaatatt ctggaggaat gcgtcaacgt
    16021 atcgttattg cgattgccct tgcctgccga cctgatgtct tgatctgtga tgagccaaca
    16081 actgccttgg atgtaactat tcaagctcag attattgatt tgctaaaatc tttacaaaac
    16141 gagtatcatt tcacaacaat ctttattacc cacgaccttg gtgtggtggc aagtattgcg
    16201 gataaggtag cggttatgta tgcaggagaa atcgttgagt atggaacggt tgaggaagtc
    16261 ttctatgacc ctcgccatcc atatacatgg agtctcttgt ctagcttgcc tcagcttgct
    16321 gatgataaag gggatcttta ctcaatccca ggaacacctc cgtcacttta tactgacctg
    16381 aaaggggatg cttttgcctt gcgttctgac tacgcaatgc agattgactt cgaacaaaaa
    16441 gctcctcaat tctcagtatc agagacacat tgggctaaaa cttggcttct tcatgaggat
    16501 gctccaaaag tagaaaaacc agctgtgatt gcaaatctcc atgataagat tcgtgaaaaa
    16561 atgggatttg cccatctggc tgactaggag gaaggaaatg tctgaaaaat tagtagaaat
    16621 caaagattta gaaatttcct tcggtgaagg aagtaagaag tttgtcgcgg ttaaaaatgc
    16681 taacttcttt atcaacaagg gagaaacttt ctcgcttgta ggtgagtccg gtagtgggaa
    16741 aacaactatt ggtcgtgcta tcatcggtct aaatgataca agtaatggag atatcatttt
    16801 tgatggtcaa aagattaatg gtaagaaatc gcgtgaacaa gctgcggaat tgattcgtcg
    16861 aatccagatg attttccaag accctgccgc aagtttgaat gaacgtgcga ctgttgatta
    16921 tattatttct gaaggtcttt acaatcaccg tttatttaag gatgaagaag aacgtaaaga
    16981 gaaagttcaa aatattatcc gtgaagtagg tcttcttgct gagcacttga ctcgttaccc
    17041 tcatgaattc tcaggcggtc aacgtcaacg tatcggtatt gcccgtgcct tggtcatgca
    17101 accagacttt gttattgcag atgagccaat ttcagccttg gacgtttctg tacgtgccca
    17161 agtcttgaac ttgctcaaaa aattccaaaa agagctcggc ctgacctatc tcttcatcgc
    17221 ccatgacttg tcggttgttc gctttatttc agatcgtatc gcagttattt acaagggtgt
    17281 tattgtagag gttgcagaaa cagaagaatt gtttaacaat ccaattcacc catatactca
    17341 agccttgctt tcagcggtac caatcccaga tccaatcttg gaacgtaaga aggtcttgaa
    17401 ggtttacgac ccaagtcaac acgactatga gactgataag ccgtctatgg tagaaatccg
    17461 tccaggtcac tatgtttggg cgaaccaaac cgaattggca cgttatcaaa aaggactaaa
    17521 ctagtaatgg ttttataatt tccatgtcaa tttttatgga aattaggctc tttgtcaact
    17581 gtagtgggtt gaagtcagct aagctcgaga aaggacaaat ttcgtccttt cttttttgat
    17641 gttcaaagcg ataaaaatcc gttttttgaa gttttcaaag tttcgaaaac caaaagcatt
    17701 gcgcttgata agtttgatga gattattggt cgcttccagt ttggcattag aatagtgtag
    17761 ttgaagggcg ttgataatct tttctttatc tttgaggaag gttttaaaga cagtctgaaa
    17821 aataggatga acctgcttaa gattgtcctc gataagttcg aaaaatttct ctggttcctt
    17881 attctggaag tgaaaaagca agagctgata gagctgatag tggtgtttca agtcttccga
    17941 ataactcaaa agcttgttta aaatctcttt attggttaag tgcatacgaa aagtaggacg
    18001 ataaaattgc ttatcactca gtttacggct atcctgttgt atgagcttcc agtagtgctt
    18061 gatagccttg tgttcatggg attttcgatg aaactgattc atgatttgga cacgcacacg
    18121 actcatagca cggctaagat gttgtacaat gtgaaagcga tcaagaacga ttttagcatt
    18181 cgggagtgaa acagtct
//
LOCUS       DAVKMJ010000040        17598 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000040 DAVKMJ010000000
VERSION     DAVKMJ010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17598
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.040"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(162..365)
                     /locus_tag="VW348_001619"
     CDS             complement(162..365)
                     /locus_tag="VW348_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9746495.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(358..1440)
                     /locus_tag="VW348_001620"
     CDS             complement(358..1440)
                     /locus_tag="VW348_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEU9746496.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTIFETAEFENLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     IIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1566..2348)
                     /locus_tag="VW348_001621"
     CDS             complement(1566..2348)
                     /locus_tag="VW348_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEU9746497.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2348..3691)
                     /locus_tag="VW348_001622"
     CDS             complement(2348..3691)
                     /locus_tag="VW348_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEU9746498.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(3803..5119)
                     /locus_tag="VW348_001623"
     CDS             complement(3803..5119)
                     /locus_tag="VW348_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEU9746499.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5313..6539
                     /locus_tag="VW348_001624"
     CDS             5313..6539
                     /locus_tag="VW348_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEU9746500.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSASGKEKTDSLTQGMTANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGILGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            6738..8312
                     /locus_tag="VW348_001625"
     CDS             6738..8312
                     /locus_tag="VW348_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEU9746501.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8576..9364
                     /gene="codY"
                     /locus_tag="VW348_001626"
     CDS             8576..9364
                     /gene="codY"
                     /locus_tag="VW348_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEU9746502.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9364..9939
                     /locus_tag="VW348_001627"
     CDS             9364..9939
                     /locus_tag="VW348_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEU9746503.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFSPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10021..10106
                     /locus_tag="VW348_001628"
     tRNA            10021..10106
                     /locus_tag="VW348_001628"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10055..10057,aa:Leu,seq:aag)
     gene            10389..11519
                     /gene="ugpC"
                     /locus_tag="VW348_001629"
     CDS             10389..11519
                     /gene="ugpC"
                     /locus_tag="VW348_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEU9746504.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFITVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(11666..11812)
                     /locus_tag="VW348_001630"
     CDS             complement(11666..11812)
                     /locus_tag="VW348_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746505.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            12020..12778
                     /locus_tag="VW348_001631"
     CDS             12020..12778
                     /locus_tag="VW348_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEU9746506.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            12865..13377
                     /locus_tag="VW348_001632"
     CDS             12865..13377
                     /locus_tag="VW348_001632"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEU9746507.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13559..14503
                     /locus_tag="VW348_001633"
     CDS             13559..14503
                     /locus_tag="VW348_001633"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEU9746508.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            14512..15189
                     /locus_tag="VW348_001634"
     CDS             14512..15189
                     /locus_tag="VW348_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEU9746509.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLIKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            15287..16045
                     /locus_tag="VW348_001635"
     CDS             15287..16045
                     /locus_tag="VW348_001635"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEU9746510.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16083..17588
                     /gene="lytC"
                     /locus_tag="VW348_001636"
     CDS             16083..17588
                     /gene="lytC"
                     /locus_tag="VW348_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEU9746511.1"
                     /translation="MSVTFFIGEERLKIKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMIQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
BASE COUNT         5282 a         3172 c         3922 g         5222 t
ORIGIN      
        1 ccctgtgcaa tacagaacta aatccttcgg ataaattaat tgtctaactt tttggggggc
       61 agttcattct acacccacta ttatgcgttt tattgtggga agattttcct cattttctag
      121 tgaaattgaa ctttttctaa catcttttga tagatgactt cttaatcaat tatcatttcc
      181 attgttgttt cttggggttt catcccttgt ctttgataaa agcggagagc accctcgtta
      241 tcattccaga cacttagggt tagattattg cagccaattt ctttagcata atagcagaaa
      301 aatgacaata aaatagcccc tagatatttt gaaaggaaag cataggggct atatagttta
      361 atcaaaataa agcaaatctt tgctggtgct tgtaaagagg tcgaagccat ccttggtaac
      421 aacaccgcag tcttcaatac gaacaccgac tttaccaggg atatagatac ctggttcaac
      481 agagaagcac atgccttctt cgatgaccat gtcgtttcct tccatgatag atgggaattc
      541 atggacatcc ataccgatac catgcccgag acggtggttg aagtactcac cataaccagc
      601 tttttcgatg atctcacggg cagcgcggtc cacttcatga gcagtcacac ctggcttgat
      661 aaagtcaaga gcagcttgtt gggcttcaag agtcaagttg taaatatctt tcttgaattg
      721 gtctggtttg ccgacagcga ctgtacgagt catatctgac gcatagccat tgaccagaac
      781 ccccaggtca aagaggagaa gagcatcatt ttcaacctta ttagctgctg gaatgccgtg
      841 tggattcgca gcattatcac cagtcaagac catggtatca aagctcattt cgtaaccttc
      901 acgtttcatg gcaaagtcaa tttgtgcgat gatatctgtc tcagtcttat caagagaaat
      961 attgtcaaaa ccaacatgaa cagccttgtc agcataaaga cctgcaacca tcattttttg
     1021 tacttcatca gctgatttga tgaggcgcat gcgttggata cgaggagtga ggttttcaaa
     1081 ctcagcagtt tcaaaaattg ttttcaaacc atggtatttg gtcaagatga gattgtcaaa
     1141 ctcaacagcg acacgtttga agtcaagttg tggaagagca tgtttgattt tttgccatgg
     1201 attttcagaa tcgacatagc ccactactgg gaaggaaacg gtgctacttg cacgttctac
     1261 ttcaagagct gggacaaaga ggagaggttc ctgatccgct aggacaaaga ggaacatttg
     1321 gcgttcatgg ggatcactgt aaaaaccagt gaggtaattg attgtgacgg ggtcagatac
     1381 gacagcgacg tctagttttt ctgattcaag atatgttagg atttgttgta atttagacat
     1441 atgctacctt ctttctaccc ctctattttg gcaaaaaatg agagaaaatg caagggagaa
     1501 gggtaaaaga aaagacaaaa aactccgaca agataacgga gttctttgat atcattttcc
     1561 tttgtttaag aaaagtcagc cttgcttttg acgtcactgt actcttcagc gatttcttgg
     1621 ctgaggatat cctcataggc agggagttgg atatcctgac catatttctt cttgagggca
     1681 gtagtaacta ggcgataagc cagattggca ttacgagaga ggataggccc gtggaagtag
     1741 gaaccaaaga cattcttata atgaacccct tcaccgacct tttcttcgtt gtttccattt
     1801 ccatagacaa cctgtcccag cggtttttgg tcatcagaga ggaaggtacg accttggtga
     1861 ttttcaaatc catagtaggt ttcatcgaaa tcttcattgt gaatcttgat gtcaccgata
     1921 aaacggttat tggtctggtt gagcgtgtag tgtcccatga cccctagccc ttcgatacgt
     1981 tttcctgaag cttcaacata atattgaccc aatagttgga aaccaccgca gatagccaga
     2041 actacaccgt cgttttggat gtagttgtca atgctctctt ttttagcagg taggtcgtct
     2101 gcaatgatac tttgttcaaa gtcttgacca ccaccgaaaa aggcgatgtc gtagtgattt
     2161 tcatcaaagt catcatggag agaaacgatg tcaacggtca catgggctcc cagtttttca
     2221 gccacatact tgagcatgag gatgtttcca ttgtccccgt aggtattcat gagatttccg
     2281 tagaggtggg caatgttgag ctgatagggg taattgccat cttttgagga aagtgaagta
     2341 taaaccatta gttcatctcc tttctaacaa tctgacgact agccagcagt tcacgaaatt
     2401 ccagcatggc agtataagtt gccagaatat aggcatgctt gcagtcttga ttctcaatgg
     2461 tcttgagaac ttgctccaga ttactcgttt cagtgatttt ctcagctgga tagccagtca
     2521 ctcggaggcg acgagcgatt tcagaatgac gaacaccgcc agcgttgatt tcaggaatgt
     2581 ccatgtcagt gatttgttca aagtctgcat cccagatcca gctagtgtca attccatctg
     2641 catagttggc attaaggagg acagataggc taaatggata aggtgctagt ttgatcattt
     2701 cgatagcttg ggttgcaccg actggatttt taatcaagac aagggtacat tccttgtcac
     2761 cgatatgaaa ggtttcttgg cgtccaaaga cagcacggct cttgtcaaat ccctgtttga
     2821 tgagttgcga atcggcacct aggaaacggg cgatggccac agcagctagg gcgttataga
     2881 tattatagag cccgccgatt tggataccgt attcttggcc gtctatgaca aagcgagagc
     2941 gattgttggt caactcaacc agttttgtca aacgatagtc gagatcagga cgtttacatc
     3001 cacaaccttc acagatatag gcacccaagt ttgcataggt attatgctca tatttgagga
     3061 tgccttggca gtcaggacag agaatccctt cggtattgta gtgagccagt tgggctggtc
     3121 ccttttccaa gtcaaaacca aaatactcta tagggtttgg aatagttggc ttgtagaaaa
     3181 gtggactgtc tccgttaagg agaacagtag cagttggaac tttccgaatg gcatccaata
     3241 tcatgttata ggtagtatag atttcaccga aacggtccat ctggtcacgg aagatattag
     3301 taatgacaaa aagactaggc tggatatagt cacagatacg agatagactg gcttcgtcaa
     3361 tttcgaggac ggcaatattt ttcccagttt tagaagattt ggctgttagg aaggttgttg
     3421 caatccctgt aatcatgttg gcaccgcttg ggttggttag aacttgacca taaacctctt
     3481 ttaaaatgcc gacagtgagg gcagttgtca gggtttttcc atttgttcca gtgacaacga
     3541 caatctcgta gttcttagct aggttttgta aaatatcttt atcaaattga agggcgactt
     3601 tccctgggag cgtacttcca cgtccaagac ggcttaaaac gaagtgggaa gaacgcccag
     3661 caagaaggcc caaagtagtt tttaagttca tgtttctatt atatcacaaa agtatatcac
     3721 aaaagaggga aaagacagat ttggtgtttc gtagaagtaa aaacagccca aagagggctg
     3781 tcagttaaga tgagatttca acttaaatcg caaacaagtc attcaagttc tcagccaagg
     3841 ttgggtgagt gaagatttgt tttgtgaagt aagtgtaagg aatcttgttg tccatagcaa
     3901 cagtaataat gttgatgatt tcttgagaac cttctgagaa gatgcttgca ccaagaattt
     3961 cttttgtttc agtattaaca acagctttga aagctccgcg aaggtctcca tttacgtgac
     4021 cacgaggcat ggctgcaaca gggatttctt tcactgcgta tggaagtttc aaatcagctg
     4081 cttggctttc agtcaaacca acttgtgaaa gtgcaggtgt gatgaacata gtatttggca
     4141 cattgagacg gtcctcaagt gtgtagctgc catctccagc aaggtagctg taaacaacac
     4201 ggaagtcatc aagtgaaatg taagtaaatt gaagaccacc gttgacatct ccaactgcaa
     4261 agacaccagg aacgtttgtt tgacagtgtt tatctacttt aatagcgcca cgttcagtta
     4321 gttcaatatc tgtattttca agttgaagtg gttctacatt tggtttgcgt ccagttgcgt
     4381 agagaagggc gtcgaaacgg taagtttcgt cttcagttac gacaagcact tggtcaccgt
     4441 cgtttttaat ttcagtagta tggatatttt gaagcaattc aataccgtct tcttccatgt
     4501 attgtttagc aagagctgcg atggaaggtt ctgcacgagg taggaatgta tccaaggcat
     4561 ctaggactgt aaccttgctt cctagtttat tgtaaaggcc agcaaattca agaccgatat
     4621 ttccgccacc aaggactcca agtttttcag gcaatttatc caagctttgg atacctgttg
     4681 agtcaaagac gtttttgctt gtagcaagtc cagggattgg caagacgttt gaaacagcac
     4741 cagtgttgat gacgatagtt tcagcagtca attcttgttt ttcatcacca gcttggattt
     4801 cgatgacttt atttgaaagg aagtgagctt cagcatcaaa gatatcgacg ccagtaccag
     4861 caacagtcgt atagttttta ccgttgaggc gaccagtgat cgtgtttttg gtagcaatga
     4921 cttcttcaaa agacaagtct ttctcagcag caaccagcaa agttttagtt gggatacaac
     4981 cgatgttgat acaagttcca ccgtacatag ctttgctacg ttcaacgagg gcaacttttt
     5041 tgccagctga agccaattta ccagctagtg ttttaccagc tttaccaaat ccgataacga
     5101 ttaaatcata agttaacatt tagaattcct cctattcgaa ttacattcta gcacaagaaa
     5161 aaaacttttg cacaattctg ctacgaaaaa gacagaaaaa tatgaaaacg cttttcaggc
     5221 aaaaaactag taattttttg acaagcttga taaactaaaa tcctatctat ttttatataa
     5281 gatagaataa atgttcgaaa ataggaggtt ttatgaaatc gaatcgttat attattgcct
     5341 ttgctggggt cattttacac ttaatgctgg gttcgactta tgcctggagt gtttatcgta
     5401 accctattat tgaaaaaacg ggatgggatc aggcttctgt tgccttcgcc tttagtctag
     5461 caatcttttg tttgggctta tcggctgcat ttatggggcg tttggtagaa aaatttggtc
     5521 cgagagtcat ggggagtcta tctgcttttc tatacgcagg tggaaatatc ttaacaggat
     5581 ttgcaataga ccgtcaggaa ctgtggttgt tgtatctagc ttatggcatt ttaggtgggc
     5641 ttggtttggg agcaggctat attacccctg tgtcaacgat tataaaatgg tttcctgata
     5701 aacgtggtct cgcaacaggt ttagcgatta tggggtttgg ttttgcttct ttattgacta
     5761 gtcccatagc gcaacatctc atcgcagggg tagggcttgt agaaactttt tatattttag
     5821 gtgcaagtta ctttattatc atgctcctag cttcacaatt cattaagcgt ccaaatgagc
     5881 aagagcttgc aattttatct gcttcaggga aagaaaaaac agactctctg acgcaaggga
     5941 tgactgcaaa tcaggctcta aaaagcaatc ggttttatat gctttggatt attttcttta
     6001 tcaacatagc ttgtggttta ggcttaattt cagcggcatc gccaatggca caggagatgg
     6061 ctggcttgtc tacaagtcat gcagcagtaa tggtgggtat tttggggatt ttcaatggat
     6121 ttggtcgctt gctctgggcg agtttgtctg actatatcgg tcgccctcta acctttagta
     6181 tattactgct tgtcaatctt ttcttttctc tctcactttg gctctttaca gattccgttt
     6241 tatttgtagt tgctatgtct attttgatga cttgctatgg agctggtttt tctttgattc
     6301 cagcttatct cagtgatatt tttggaacca aggaattggc cgctctgcat ggttatattt
     6361 taacagcttg ggcaatggct ggtttagcgg gacctatttt attagcagag acttataaaa
     6421 tggctcattc gtacacacaa accttgttcg tttttctcat tttatacagt atcgccttgg
     6481 ctttgtctta ttatctaggt cgttcaatca aaaaagaaag tcaaaaaccg cttacatgat
     6541 tttctgtaga aatggggcta tcttttgctc tggtcttgtg ttatactaga taggttgcaa
     6601 agaaaacagt acttttcttt tgtggaaaag aagcaacacg attttatatc tagttatatg
     6661 aaaatacgtc ataaaaagaa aagtataaac taagccctat agggtggctt cgcaccacct
     6721 ttagaaagaa gaataacgtg aaatttaatg aattaaactt gtctgctgat ttgctagcag
     6781 aaattgaaaa agctggtttt gtagaagcta gtcctatcca agaacaaact attcctttgg
     6841 cccttgaagg caaggatgtt atcggtcaag ctcagactgg tacaggaaaa actgcagcct
     6901 ttggcttgcc tacccttgaa aaaatccgta cagaagaagc gactatccaa gctttggtca
     6961 tcgctccaac tcgtgaacta gctgtccaaa gtcaagaaga actcttccgc tttggtcgta
     7021 gtaagggagt caaagtccgt tcagtatatg gcggatcaag cattgaaaaa caaattaagg
     7081 ctcttaaatc tggtgcccat atcgtggtgg gaactccagg tcgcctcttg gacttgatta
     7141 aacgcaaggc cttgaaatta caagacattg aaacccttat ccttgacgaa gcggatgaaa
     7201 tgcttaacat gggcttcctt gaagacatcg aagccattat ttcccgtgta cctgagaacc
     7261 gtcaaacttt gcttttctca gcaactatgc cagatgccat caaacgtatc ggtgttcagt
     7321 ttatgaaagc ccctgaacat gtcaagattg cggctaagga attgacaaca gaattggttg
     7381 accagtacta tatccgtgtt aaggaacaag aaaaatttga caccatgact cgtctcatgg
     7441 atgtggcaca accagaactc gctattgtat ttggtcgtac caaacgccgt gtggatgaat
     7501 tgactcgtgg tttgaaaatt cgtggcttcc gtgcagaagg aattcatggc gacctagacc
     7561 aaaacaaacg tcttcgtgtc cttcgtgact ttaaaaatgg caatcttgat gttttggttg
     7621 cgacagacgt tgcagcgcgt ggtttggata tttcaggtgt gacccatgtc tacaactacg
     7681 atattccaca agatcctgag agttatgttc accgtatcgg tcgtacaggt cgtgctggta
     7741 agtcaggtca atctattact tttgttgctc caaacgaaat gggttacctt caaatcattg
     7801 aaaacttgac taagaaacgc atgaaaggtc tcaaacctgc aagtgtagaa gaatccttcc
     7861 aatcaaaaaa acaggtagct ctcaagaaaa tcgaacgtga ttttgcagat gaaaccattc
     7921 gtgccaactt tgagaaattt ggtaaggatg ctcgcaaatt ggctgctgag tttactccag
     7981 aagaattggc aatgtatatc ttgagtctga cagtccaaga cccagatagc cttccagaag
     8041 tggagattgc acgtgaaaaa ccactaccgt ttaaaccatc aggtaatggt ttcggtggta
     8101 aagctaaggg aggtcgtgga ggccgtcgtg gggacgaccg tcgagagcgt gatcgccgtg
     8161 gcaatggtcg ccgtgatgag ttcaaaaaag gaagtcgtgg caacgatcgt tttgataagg
     8221 aaaaacgtta ccgtaaggat aataaaaaac cacgcaatac tttaagcgaa aagcaaacag
     8281 gctttgttat tcgtaacaag ggcgataaat aagaaaaagc ggttcaaaat gaatcgcttt
     8341 tttatataag gagaccgaat gtgaaaagac aaataaaatt attatattat cttttataat
     8401 gttatgatac acaaaaatag gcaacttgtc aatagaaaag gaacaattta attaaaaata
     8461 ttctggtttt taattaaatt gtaagtcaat gcaagtcaat aaggaatttt cagataatta
     8521 ttgaaaaaga gacgttttta tgttataatg atagcgatta aattcgaggt gaaaaatggc
     8581 acatttatta gaaaaaacta gaaaaattac atcaattttg aaacgctcag aggagcagtt
     8641 gcaggatgag cttccttaca acgctattac gcgtcagtta gcggatatta ttcattgcaa
     8701 tgcctgcatt atcaatagta agggacgtct gcttggctat tttatgcgtt ataaaacaaa
     8761 tacagatcgc gtagagcaat tcttccaaac taagattttc ccagatgact acgttcaagg
     8821 ggctaatatg atttacgaaa cagaagcaaa cttgcctgtt gagcatgata tgagtatttt
     8881 ccctgttgag agtagagatg attttccaga tggcttgacg actattgcac cgattcatgt
     8941 atcggggatt cgccttggtt ctttgattat ttggcgtaat gataaaaaat tcgaagatga
     9001 ggacttggtt cttgttgaga ttgccagtac cgttgttggg attcagcttc ttaacttcca
     9061 acgtgaagaa gatgagaaaa atattcgtcg tcgtactgct gtcaccatgg cggtcaatac
     9121 cctttcttac tccgaactcc gtgctgtttc agcaatttta ggggaattaa atggaaatga
     9181 agggaagttg actgcgtcag tgattgcaga tcgtatcgga atcactcgct ctgtgattgt
     9241 caatgctctt cgtaaacttg agtctgcggg gattattgaa agtcgctcac ttggaatgaa
     9301 gggaacctat cttaaggtct tgatttcaga tatttttgaa gaagtgaaga aaagagatta
     9361 ctaatgacaa aggctttaat ttcgattgat tatacagaag attttgttgc tgatagtggg
     9421 aaactaacag caggtgctcc agctcaggcg atttcggatg ccatcagcaa ggtaactcga
     9481 ttagcttttg aacgaggaga ttatatcttc tttactattg atgctcatga agaaaacgat
     9541 tgtttccatc cggaaagtaa gttattttct cctcataatc tgattgggac gagtggacgg
     9601 aatttatatg gagatttggg gatcttttat caagagcatg gttcagacag tcgtgtcttt
     9661 tggatggata aacgccatta ctcagctttt tcagggactg acctagatat tcgtttgaga
     9721 gagcgtagag tgtctaccgt tatcttaaca ggtgtcttga cggatatctg tgtcctacat
     9781 acagctatag atgcctataa tctaggatat gacatcgaga ttgttaaacc agctgttgct
     9841 tccatctggc ctgaaaatca tcaatttgcc ctaggtcatt tcaaaaatac actcggagct
     9901 aagttagtag atgaaaatct aaatgaactt tctgagtaac ctggttggtg aaaatgaaaa
     9961 aatttgaaaa aaagtgttga caagcatccc aaaagttgat atactagtaa agtaatcgat
    10021 gcggggatgg cggaattggc agacgcgcag gactaaggat cctgtgaccg ctttaggtcg
    10081 tgagggttca agtccctctc tccgcatagg aaaagagtta gctaaagcta gctcttttgt
    10141 atttctctaa aaaattagaa tccagtcaaa tgtagtggag aatcagcgaa aatatgggaa
    10201 aactgatcct tgtttctgct tttgtcatag aagaataata aagattatct tcttcaaatt
    10261 ctccgatatt ctctaaagtt ttgtgcaagt tgcacagaac ttttttattt ttttggtcat
    10321 cttgccatag aaatataaag cgttttcatc tataatataa ttatcaaaag acaaaaggag
    10381 ttcacctcat ggtagaattg aatcttaaaa atatttacaa aaaatatcca aacagcgaac
    10441 actattcagt tgaagatttc aacttgaaca tcaaagataa agaatttatc gttttcgtag
    10501 gaccttcagg atgtggtaaa tcaactacac tccgtatgat tgctggtctt gaagacatta
    10561 cagaaggtac tgcatctatc gatggcgtgg ttgtcaacga cgtagctcca aaagaccgtg
    10621 atatcgccat ggtattccaa aactacgctc tttacccaca catgactgtt tatgacaaca
    10681 tggctttcgg tttgaaattg cgtaaataca gcaaagaaga cattaacaaa cgtgttcaag
    10741 aagcagctga aatacttgga ttgaaagaat tcttggaacg taaaccagct gacctttcag
    10801 gtggtcaacg tcaacgtgtt gccatggggc gtgcgattgt ccgtgatgcg aaagtattct
    10861 tgatggacga acctttgtca aacttggatg ccaaacttcg tgtatcaatg cgtgctgaaa
    10921 tcgctaaaat tcaccgtcgt atcggagcta caactatcta tgtaactcac gaccaaacag
    10981 aagcgatgac acttgcagac cgtatcgtta ttatgtcagc tactaagaac cctgctggta
    11041 caggtactat cggacgtgta gaacaaatcg gtactcctca agaagtttac aaaaatccag
    11101 ttaacaaatt cgttgcagga ttcatcggaa gcccagctat gaacttcatc accgtgaaat
    11161 tggttggtag cgaaattgtt tctgacggtt tccgtttgaa agtgccagaa ggagcattga
    11221 aagttcttcg tgaaaaaggc tacgaaggaa aagaattgat ctttggtatc cgtccagaag
    11281 acgtgaatgc agaacctgct ttccttgaaa cattcccaga ctgtgttgta aaagcgacta
    11341 tctctgtatc agaactgctt ggttcagaat ctcaccttta ctgccaagtt ggtaaagacg
    11401 agtttgttgc aaaagttgat gctcgtgact acttgcaaac aggtgcaaca gttgagcttg
    11461 gatttgactt gaacaaagca cacttcttcg atgtagaaac tgaaaaaaca atctactaaa
    11521 ataaataaaa ttcaaagcac tacaagaaaa gatatctctt tatcaattgt agtggagaga
    11581 tatcagttaa tctagggaga gaaacaaaat gcttctctcc tttttgctag ggaagtcata
    11641 ttatgcatct atattgtgat gctctttaat actcttcgaa aatctcttca aaccacgtca
    11701 acgtcgcctt gccgtacgta tgattactga tttcgtcagt tttatctgca acctcaaaga
    11761 tgtactttga gcagcttacg gctagtttcc tagtttgctc tttgatttcc attgagtatt
    11821 atttgtgggt accatctaca agtgaagcta tatgcgtaaa ctacgtgagc aattgaattc
    11881 gaactagaga ggtaataata aatttatgct atagttatgg tgacttgtat gcttttgatt
    11941 ctagtttatc aaataataga ttagaattgt cagataatat cattttgtgt tataatgaag
    12001 aaaaaacaga ggtgttcaaa tgtcagaagc aggtcataag tttttagcaa aattggggaa
    12061 aaaacgctta cgtccaggtg gaaagcgtgc cacagattgg ttaattgcag aaggaggatt
    12121 ttcaaaagaa aagagaatac tagaggttgc gtgtaatagg ggaactacag caattgagtt
    12181 ggcacagcgt tttggttgca agataactgc tgttgatatg gatgctcaag ctttagaagt
    12241 ggctaaaaaa tctgctggaa cggcaggtgt tgctcattta atcagttttg aaagagcaaa
    12301 tgcaatgaaa cttccttatc aagatgctag ttttgatatt gttataaatg aagctatgct
    12361 gactatgcaa gccgatcaag ctaagaaaaa atgtgtaatg gaatatctaa gggtattaaa
    12421 acctggaggt cttctcttga cacatgatgt gcttcttaag gaagctaaag agtctatcag
    12481 acaggaatta tcacaagcaa ttcatgtaaa tgtaggtcct ttaactcaag atggttggga
    12541 acaggtgatg atagaatcag gttattgtga tgtgaaagca ttgactggtg aaatgacatt
    12601 aatgaaatta tcgggtatga tttatgacga aggtttgcta ggaactttga aaatttgtgt
    12661 aaatgcttgt aaaaaggaga atagaaagca gtttttaact atgtataaaa tgtttgctaa
    12721 gaataaacag aaattgggct ttattgcgat ggctagttat aaatcgtcaa aacgttagat
    12781 aattattgaa gttaactttt ccttttttct ttcttaaaaa atatgctata atagagagta
    12841 aaaaactttg aaagaaagaa aaagatgaat ttaaaagatt acattgcaac aattgaaaat
    12901 tatccaaagg aaggcattac cttccgtgat attagtcctt tgatggctga tggaaatgct
    12961 tatagctacg ctgttcgtga aatcgttcag tatgctactg acaagaaagt cgacatgatc
    13021 gtgggacctg aagctcgtgg atttatcgtg ggttgtccag ttgcctttga gttgggaatt
    13081 ggttttgcgc ctgttcgtaa gccaggtaaa ttgccacgcg aagttatttc tgctgactat
    13141 gaaaaagagt acggtgtcga taccttgact atgcacgcgg atgccattaa gccaggtcaa
    13201 cgtgttctta ttgtagatga ccttttggcg acaggtggaa ctgttaaggc aactatcgag
    13261 atgattgaaa aacttggtgg tgttatggca ggttgtgcct tccttgttga attggatgaa
    13321 ttgaacggcc gtgaaaaaat tggtgactac gactacaaag ttcttatgca ttattaatga
    13381 aaacagtccc tagggctgtt ttctctacac taggatataa aaatagacta taactagtta
    13441 gagaaaaact ataattgaaa actatatctt cttgcagtat aataaaagga ctaagtgttt
    13501 gagatttgtc ttcaaacata tgcaattatt cctgaaagag tacagttagg agagggttat
    13561 gccgattcga attgataaaa aattgccagc tgttgagatt ttacggacag agaatatctt
    13621 tgtcatggat gatcaacgtg ctgcccacca agatatccgt cctttgaaga ttttaatttt
    13681 aaatctcatg ccacagaaaa tggtcacaga gacccagttg ttgcgccact tggctaatac
    13741 acccctacaa ctggatattg attttctcta tatggagagc caccgttcta aaacaactcg
    13801 ttcagagcac atggagacct tctataaaac ttttcctgaa gtcaaggatg agtattttga
    13861 tgggatgatc atcacgggtg ctccagttga gcatttacca tttgaggaag tggactattg
    13921 ggaggaattt agacagatgc ttgagtggtc taagactcat gtctattcga cccttcatat
    13981 ctgttggggg gctcaggctg ggctttatct gcgctatggt gtagaaaaat accagatgga
    14041 cagtaagcta tcaggtattt atcctcagga caccctaaaa gagggtcacc ttctatttag
    14101 aggctttgat gatagctatg tatcccctca ttcacggcac acggagattt ctaaggaaga
    14161 ggtcttaaac aagaccaatc tcgagatttt atcagaagga cctcaggttg gggtttctat
    14221 tttggccagt cgtgatttac gagaaattta tagttttggt catttggagt atgaccgtga
    14281 taccttggca aaagagtatt ttcgagatcg tgatgcaggt ttcgacccac atattccaga
    14341 aaattacttt aaagatgatg atgttaatca ggtaccttgt ctttgttggt cttcatctgc
    14401 agccctcttt ttcagtaatt gggtaaacca tgcggtctat caggagacgc cttttgattg
    14461 gagaaagata gaagatgatg catctgcata tgggtattta taagaggaat tatgacatat
    14521 ttagacgctt ttaaatcagg taccttggtt ttaccgagtg ccctgctctt gcattttaag
    14581 gaactctttc cttctagcga cgattttctg gtttggcaat ttttctattt gcaaaatacg
    14641 acaggcttag aagaaatgtc gccaagccag attgctgaaa ggattggcaa ggaaatttcg
    14701 gatgtcaacc agtccatttc taatctgacg gaaaggggac tgctccagta tcgtactatc
    14761 gaattaaatg gcgaaattga attgctcttt gatgctagtt tggccttgga acgtttggat
    14821 gacctgtttg gagcagttcg ttcaagttca gaccagctaa cacctcaaaa ccagctcaag
    14881 gatttggtgg aaaccttcca gcaggagttg ggacgattgt tgacgccttt tgagattgag
    14941 gatttgatca agacactaaa ggaagatgga accagtgctg acttgattaa ggaggctctt
    15001 cgtgaagctg ttttgaatgg aaaaccaaac tggaagtaca ttcaggcgat tttgagaaac
    15061 tggcgccatg aaggaatcaa gagtgtggct caaattgagg ccaagagagc agaaagagaa
    15121 gcaagcaatc ctcagttgac acaggtatct gcagatttca gaaatgccat ggatctctgg
    15181 aaggattaat ccatgcaagt aggcttgaaa tccgagtaag atttgcaagc tgtgtataat
    15241 tgtgatagaa taaatagaaa ataaattgaa aaaagaggta tgtgaaatgt cacgtaaacc
    15301 atttatcgct ggtaactgga aaatgaacaa aaatccagaa gaagctaaag cattcgttga
    15361 agcagttgca tcaaaacttc cttcatcaga tcttgttgaa gcaggtatcg ctgctccagc
    15421 tcttgatttg acaactgttc ttgctgttgc aaaaggctca aaccttaaag ttgctgctca
    15481 aaactgctac tttgaaaatg caggtgcttt cactggtgaa actagcccac aagttttgaa
    15541 agaaatcggt actgactacg ttgttatcgg tcactcagaa cgccgtgact acttccatga
    15601 aactgatgaa gatatcaaca aaaaagcaaa agcaatcttt gcgaacggta tgcttccaat
    15661 catctgttgt ggtgaatcac ttgaaactta cgaagctggt aaagctgctg aattcgtagg
    15721 tgctcaagta tctgctgcat tggctggatt gactgctgaa caagttgctg cctcagttat
    15781 cgcttatgag ccaatctggg ctatcggtac tggtaaatca gcttcacaag atgatgcaca
    15841 aaaaatgtgt aaagttgttc gtgacgttgt agctgctgac tttggtcaag aagtcgcaga
    15901 caaagttcgt gttcaatacg gtggttctgt taaacctgaa aatgttgctt catacatggc
    15961 ttgcccagac gttgacggtg cccttgtagg tggtgcgtca cttgaagctg aaagcttctt
    16021 ggctttgctt gactttgtaa aataatcagt aagtagcaaa agctaggtgg aacagcattc
    16081 agatgtctgt tacatttttt ataggagagg aaagattgaa aataaaaatt ggattagcaa
    16141 gtatctgttt actaggcttg gcaactagtc atgtcgctgc aaatgaaact gaagtagcaa
    16201 aaacttcgca ggatacaacg acagcttcaa gtagttcaga gcaaaatcag tcttctaata
    16261 aaacgcaaac gagcgcagaa gtacagacta atgctgctgc ccactgggat ggggattatt
    16321 atgtaaagga tgatggttct aaagctcaaa gtgaatggat ttttgacaac tactataagg
    16381 cttggtttta tattaattca gatggtcgtt actcgcagaa tgaatggcat ggaaattact
    16441 acctgaaatc aggtggatat atggcccaaa acgagtggat ctatgacagt aattacaaga
    16501 gttggtttta tctcaagtca gatggggctt atgctcatca agaatggcaa ttgattggaa
    16561 ataagtggta ctacttcaag aagtggggtt acatggctaa aagccaatgg caaggaagtt
    16621 atttcttgaa tggtcaagga gctatgatac aaaatgaatg gctctatgat ccagcctatt
    16681 ctgcttattt ttatctaaaa tccgatggaa cttatgctaa ccaagagtgg caaaaagtgg
    16741 gcggcaaatg gtactatttc aagaagtggg gctatatggc tcggaatgag tggcaaggca
    16801 actactattt gactggaagt ggtgccatgg cgactgacga agtgattatg gatggtgctc
    16861 gctatatctt tgcggcctct ggtgagctca aagaaaagaa agatttgaat gtcggctggg
    16921 ttcacagaga tggtaaacgc tatttcttta ataatagaga agaacaagtg ggaaccgaac
    16981 atgctaagaa aatcattgat attagtgagc acaatggtcg tatcaatgat tggaaaaagg
    17041 ttattgatga gaacgaggtg gatggtgtca ttgttcgtct aggttatagc ggtaaagaag
    17101 acaaggaatt ggcgcataac attaaggagt taaaccgtct gggaattcct tatggtgtct
    17161 atctctatac ctatgctgaa aatgagaccg atgctgagaa tgacgctaaa cagaccattg
    17221 aacttataaa gaaatacaat atgaacctgt cttaccctat ctattatgat gttgagaact
    17281 gggaatatgt aaataagagc aagagagctc caagtgatac agacacttgg gttaaaatca
    17341 tcaacaagta catggacacg atgaagcagg cgggttatca aaatgtatat gtctatagct
    17401 atcgtagttt attacagacg cgtttaaaac acccagatat tttaaaacat gtaaactggg
    17461 tagcggccta tacgaatgct ttagaatggg aaaaccctta ttattcagga gaaaaaggtt
    17521 ggcaatatac ctcttctgaa tacatgaaag gaatccaagg gcgcgtagat gtcagcgttt
    17581 ggtattaagc gatgattt
//
LOCUS       DAVKMJ010000041        17123 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000041 DAVKMJ010000000
VERSION     DAVKMJ010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17123
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.041"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            415..1461
                     /gene="pheS"
                     /locus_tag="VW348_001637"
     CDS             415..1461
                     /gene="pheS"
                     /locus_tag="VW348_001637"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEU9746512.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1461..1970
                     /locus_tag="VW348_001638"
     CDS             1461..1970
                     /locus_tag="VW348_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9746513.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            2047..4452
                     /locus_tag="VW348_001639"
     CDS             2047..4452
                     /locus_tag="VW348_001639"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEU9746514.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNESAADALSVSIGTDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLAETDLVITVADKPVALAGVMGGQATEISEKS
                     SRVILEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLEVTYTATAEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEGALQPAVPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNA
                     EVR"
     gene            complement(4520..5521)
                     /locus_tag="VW348_001640"
     CDS             complement(4520..5521)
                     /locus_tag="VW348_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEU9746515.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTDSGIAPVTVIVKKSYDFYTKAETFHTTRFGTIVLHSRKQDIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            5677..6166
                     /locus_tag="VW348_001641"
                     /pseudo
     CDS             5677..6166
                     /locus_tag="VW348_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6250..6516
                     /locus_tag="VW348_001642"
     CDS             6250..6516
                     /locus_tag="VW348_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9746516.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGKTSPQLDTVLKVLASLGKTLAIVPLEQGKS"
     gene            6777..9026
                     /gene="metE"
                     /locus_tag="VW348_001643"
     CDS             6777..9026
                     /gene="metE"
                     /locus_tag="VW348_001643"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEU9746517.1"
                     /translation="MSTTIVGFPRLGEFRELKFTTEKYFRKEISEEELLSAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFTTERVGENAELRARIAG
                     LTDADYTRLPVFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVAPDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            9090..9956
                     /gene="metF"
                     /locus_tag="VW348_001644"
     CDS             9090..9956
                     /gene="metF"
                     /locus_tag="VW348_001644"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEU9746518.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNDNIISALQDMQELVPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKERAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            10641..12854
                     /gene="pnp"
                     /locus_tag="VW348_001645"
     CDS             10641..12854
                     /gene="pnp"
                     /locus_tag="VW348_001645"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEU9746519.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMTGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            12870..13487
                     /gene="cysE"
                     /locus_tag="VW348_001646"
     CDS             12870..13487
                     /gene="cysE"
                     /locus_tag="VW348_001646"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEU9746520.1"
                     /translation="MGWWHETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KYDFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            13499..14383
                     /locus_tag="VW348_001647"
     CDS             13499..14383
                     /locus_tag="VW348_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9746521.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            14470..15813
                     /locus_tag="VW348_001648"
     CDS             14470..15813
                     /locus_tag="VW348_001648"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEU9746522.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            15806..16192
                     /locus_tag="VW348_001649"
     CDS             15806..16192
                     /locus_tag="VW348_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEU9746523.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            16196..17080
                     /locus_tag="VW348_001650"
     CDS             16196..17080
                     /locus_tag="VW348_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEU9746524.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
BASE COUNT         5089 a         3346 c         3905 g         4783 t
ORIGIN      
        1 tatagtagac tgaatctaaa atagtacgaa acaattgcta aaacatttat agaaattaat
       61 tttactttcc caatcgattt gttctcatct tatttcaatc cgctataaag ttagataaga
      121 ataagctaac aagcagaagt aagataggtc ttgcaagaat ggtaaaaatc tgataaacta
      181 agtagtaatt gaataggaat ctgaaagact agtagcccaa gggaagtata tcagggagga
      241 gagccgtgac tgcaagctct ctatatgaaa gctgggtgaa ttcacttgcg catggattta
      301 gaaatgaagg tctgacttgt cagatgaaaa cggatggtac cgcgtgtcaa cgctccgagt
      361 ggagtttttg gcatgtggtt ttctttttat ctacgagaga ctgatggagg aaatatgtca
      421 actattgaag aacaattaaa agcgcttcgc gaagaaacgc tggctagctt gaagcagatt
      481 actgctggaa atgaaaaaga gatgcaagat ttgcgtgtct ctgtccttgg taaaaagggt
      541 tcgctcactg aaatcctcaa agggatgaaa gatgtttctg ctgagatgcg tccaatcatc
      601 gggaaacacg tcaatgaagc tcgtgatgtc ttgactgctg cttttgaaga aacagctaag
      661 ctcttggaag aaaagaaagt cgcggctcaa ctggctagcg agagtatcga tgtgacgctt
      721 ccaggtcgtc cagttgcgac tggtcaccgt cacgttttga cacaaaccag tgaagaaatc
      781 gaagatatct tcatcggtat gggttatcaa gtcgtggatg gttttgaagt ggagcaagac
      841 tactataact ttgaacgtat gaaccttcca aaagaccacc cagctcgtga tatgcaggat
      901 actttctata tcactgaaga aatcttgctc cgtacccaca cgtctccagt tcaggcgcgt
      961 gctatggatg cccatgattt ttctaaaggt cctttgaaga tgatctcgcc agggcgtgtc
     1021 ttccgtcgcg atacggacga tgcgacccac agtcaccaat tccaccaaat cgaaggcttg
     1081 gtagttggga aaaatatctc tatggctgat cttcaaggaa cgcttcagtt gattgtccaa
     1141 aaaatgtttg gtgaagagcg tcaaattcgt ttgcgtccat cttacttccc attcacagag
     1201 ccatctgttg aggtggatgt ttcttgcttc aagtgtggtg gagaaggctg taatgtatgt
     1261 aagaaaacag gttggatcga aattatgggg gccggtatgg ttcacccacg tgtccttgaa
     1321 atgagtggta tcgatgcgac tgtatactct ggctttgcct ttggtcttgg acaagagcgt
     1381 gtagctatgc tccgttatgg aatcaacgat atccgtggat tctaccaagg agatgtccgc
     1441 ttctcagaac agtttaaata atgattagaa aagtagaaat ggcagatgtt gaggtgttgg
     1501 ctaaaattgc caaacaagcc tttcgtgaaa cctttgcgta tgataatacg gaagagcagt
     1561 tacaggaata ctttgaagag gcttatagtc tgaaaacttt gtcaactgag ttgggaaatc
     1621 ctgactctga aacctatttc attatgcatg aggaggagat agctggtttt ctcaaagtca
     1681 actggggaag tgctcaaact gagagagaat tagaggacgc ttttgaaatt caacgcctct
     1741 atgtgctaca aaaattccaa ggatttggac taggtaagca actgtttgaa ttcgcacttg
     1801 aacttgctac aaaaaatagt ttttcttggg cttggttagg tgtttgggag cataatacaa
     1861 aagctcaagc gttttataat cgatatggtt ttgaaaaatt tagccaacat cattttatgg
     1921 ttggtcaaaa agtagatacg gattggttac tgagaaagaa attaaggtaa gaagaggatt
     1981 cttctattga aatgatagga aaggaaaaga actagagtga caactgtcat tctggagaac
     2041 taaattatgc ttgtatctta taaatggtta aaagaattgg tggacattga tgtgccatca
     2101 caagagttgg ctgaaaaaat gtcaactaca ggaatcgagg tagagggtgt cgaatcacca
     2161 gctgctggtc tctcaaaaat tgtcgtcggt gaggtcttgt cttgcgaaga tgtgccagag
     2221 actcacctcc atgtttgtca ggttaacgtt ggcgaagaag aagagcgtca gatcgtttgt
     2281 ggtgccccaa atgtgcgtgc tgggatcaag gtcatggtgg ctcttccagg agctcgtatc
     2341 gctgataact acaaaatcaa aaaaggaaaa atccgtggtt tggagtcact tggaatgatc
     2401 tgttcacttg gtgaattggg aatttctgac tcagttgtgc ctaaggaatt cgcagatggc
     2461 atccaaatct tgccagaaaa tgccgtgcca ggtgaggaag tcttttctta cctagacttg
     2521 gatgatgaaa tcatcgaact ttccatcaca ccaaaccgtg cagatgccct ttctatgtgt
     2581 ggagtggctc acgaagtggc agccatctat gacaaggcag tcaactttaa agaatttact
     2641 ctaacagaaa ctaatgaatc tgcggcagat gccctttctg tcagcattgg gacagacaag
     2701 gcgccttact atgcagctcg tatcttggac aatgtgacta tcgcaccaag tccacaatgg
     2761 ttgcaaaacc ttctcatgaa cgaaggcatc cgtcccatca ataacgttgt agacgtgaca
     2821 aactacatcc tgctctactt tggtcaacct atgcatgctt ttgacttgga cacatttgaa
     2881 gggactgaca tccgtgtgcg tgaagcgcgt gctggtgaaa agttggtgac cttggacggt
     2941 gaagaacgag acttggctga gacagacctc gtgattacag ttgctgacaa accagtagcc
     3001 cttgccggtg ttatgggtgg tcaggctaca gaaatttctg aaaaatctag tcgtgttatc
     3061 cttgaagctg ctgtttttaa tggcaaatct atccgtaaga caagtggtcg cctgaacctt
     3121 cgttctgagt catcttctcg ctttgaaaaa ggaattaatg tggcaacagt taatgaagcc
     3181 cttgatgcgg cagctagcct gattgcggaa cttgcaggtg cgacggtgcg taagggtatc
     3241 gtttcagcgg gtgagcttga tacttcagat gtagaagttt cttcaactct tgctgatgtt
     3301 aaccgtgtcc tcggaactga gctgtcttat gctgatgtcg aagacgtctt ccgtcgtctt
     3361 ggctttggtc tttctggaaa tgcagacagc tttacagtca gcgtaccacg tcgtcgttgg
     3421 gatatcacaa tcgaagctga tctctttgaa gaaatcgctc gtatctatgg atatgaccgt
     3481 ttgccaacca gccttccaaa agacgatggt acagctggtg aattgactgt gacacaaaaa
     3541 ctccgccgtc aagttcgtac cattgctgaa ggagcaggtt tgacagaaat catcacctat
     3601 actctaacaa ctcctgaaaa agcagttgag tttacggctc aaccaagtaa ccttacggaa
     3661 ctcatgtggc caatgactgt ggatcgttca gtcctccgtc aaaatatgat ttcaggtatc
     3721 cttgataccg ttgcctacaa cgtggctcgt aagaataaaa acttggccct ttacgagatt
     3781 ggaaaagtct ttgaacaaac aggtaatcca aaagaagaac ttccaaatga aatcaacagt
     3841 tttgcctttg ccttgacagg cttggttgct gaaaaagatt tccaaacagc agcagttcca
     3901 gttgatttct tctatgctaa gggaatcctt gaagcgctct ttactcgctt gggactagaa
     3961 gtgacctata cagcaacagc tgagattgcc agccttcacc caggacgtac agcagtcatt
     4021 tcactcggtg accaagttct tggttttctt ggccaagtgc atccagtcac tgccaaggct
     4081 tacgatattc cagaaacgta tgtagctgag cttaaccttt cagccatcga aggggcgctc
     4141 caacctgctg ttccatttgt ggaaatcacg aaattcccag cagtcagccg tgacgttgcc
     4201 cttctcctca aggcagaagt aactcaccaa gaagttgtag atgctatcca agctgccggc
     4261 gtgaaacgtt tgacagatat caaactcttt gacgtcttct caggtgagaa attgggactt
     4321 ggtatgaagt ccatggctta tagcttgacc ttccaaaatc cagaagatag cttaacggac
     4381 gaagaagtcg cacgctatat ggaaaaaatc caagcatcgc tcgaagaaaa agtgaatgca
     4441 gaagtgcgtt aaacgatagt aggatataaa ttccccctct agtttatgaa cactagaggg
     4501 gtgattttat ataaaataat taaaatgtga tttctgtaaa aatacatcta tgatcagagt
     4561 tttgaaaact tacaatgtct aaatctttaa catagtagtg gtttttaggc aataaaatat
     4621 gatctatcgt tgcattaaaa agttttggac tttggctatt ccaagttcct ctttcaaaag
     4681 gtggcagtgc atttaatgcg tccctatgag agcttatttt tgcaagtgct ccatgacgca
     4741 tagttgcatt aaaatcacct gcaataatag cctttggata ttttgaagcc aattgattat
     4801 gaatgatgtt taagtcttgc ttccagattt ccattaaacc tggcagagga ggagcagtat
     4861 gcaaagcaat gatatctggt atatcttgtt ttctcgaatg taatacaatt gtcccgaacc
     4921 gtgttgtatg aaaagtttca gcttttgtat agaaatcgta acttttcttg acaatcacag
     4981 tcacaggagc tattccactg tcagtaggtg gagaagtaaa aatatcatag ttggccatag
     5041 aaagtccaac ttgatgaaac aatagtttga ttctctggtt ttcttgctca cctctgatat
     5101 tggtagctag ttcagggaat atagccatat cggcgtcaaa atggctaaaa attcgctcaa
     5161 tatgttgtgc ttctatttga ttagcgacgt tccaagttac taattttaag gttttagtct
     5221 tatttgatgc ggaagaaagg gttttatctg ttccgaataa tagtaatatg agcgataata
     5281 agagcaaaat gccagagtaa aaccgtattt gtttattttt cttgtaaaaa gatagggaaa
     5341 aaaatacgaa acttaaaatg gcagccatag ttgcagtagc taaggggaag gcataaatct
     5401 gtgccaagat aggtctggta gatagccaaa tattaagatt agaagatgga aaaaaagaat
     5461 aagttatgat agggataaca aagagaatga ccgaaagggc agagagaaat gttttaatca
     5521 ttgtgtgagt acctcaattt gcaatggttg ctcggagcta atgtgacttt gtgactttac
     5581 ttgattgata ttctttttct tgtcttcctt atagattaag tacaacccaa gtaaaaaaag
     5641 tccaatttaa gattgaaatg attaaaaggc acagagatgc aagacaatta tactacaaaa
     5701 ggtaaacatt tgacaatcga tagccgtcgc ttaatcgaaa gatggaaaaa agaaggaaaa
     5761 tcaaatagag aagttgcctc tctacttgga aaagctcctc aaactatcca cactgaaatc
     5821 aagcgtggga cagtccgaaa atgtcttgga aaagggcgct tcaaagaggt ttattctgcc
     5881 gactacgctc aacagtctta tgaaaacaat cgcaagcgct cggtcaagaa atcaagcttg
     5941 accaaggaac taaaggaaaa gattctccac tatacataac caaaaatttt tgcctgaaat
     6001 gatggtgatg gctaaagggg ttaacgtggg aatttcaacc atttactatt ggattcatca
     6061 tggaaagttg gggttaagca aacaggattt gctttatcct agaaaaggaa aatctgttaa
     6121 gaaacaagtt agtcccaatt ttaaacccgc tgatcaatct atcgaatcat aattcgctca
     6181 tttttttaaa aatacataga cgtaaaaaaa agagggttaa gtgatgaaga atagtgctat
     6241 tgggagtaat tggaaggatg tccatctgag ctctttagca aggaggaaat ccttgaaagt
     6301 gatatgcgag tggctatcat gagcgagttg attgaggcta ggtatgaaca aggaatcagt
     6361 cagaaaaagc tggaagaagt cagtggaata agccagcctg tcatagctag gatggagaca
     6421 ggaaagacta gtcctcagtt ggatacagtc ttaaaagtcc tagccagttt aggaaagaca
     6481 ctagcaatcg tcccacttga acagggaaaa agttgactag aatcagttat agtcttttct
     6541 aataacaagc catagtcact tataagaatt actaataacg cgtttgagca ttctaactaa
     6601 aatacagcta taaaacaagc tatacaaagg atttgagacg tttgcttcaa gtctttttct
     6661 tttgtccgaa acagatatat agtttcaaac tatatcaaac cctaattttt tacaattata
     6721 cagacgcttt cttttctgtt aagatagttt caacaacaaa ttttggagga cacatcatgt
     6781 caactacaat cgtcggtttc cctcgtttgg gcgaattccg tgaattaaaa tttacaactg
     6841 aaaaatactt tagaaaagaa atctcagagg aagaactttt atcagcagca aaagacttgc
     6901 gtgctaaaca ctggaacatt gtcaaagaaa aaggcatcac tgaaattcca tcaaatgact
     6961 tttctcacta tgataacttc ctagatgcgg ctttcctttt caacgtggtg cctgcatccg
     7021 ttcaaaactt ggacttgtct gaccttgagc gctacttcgc tttgggacgt ggttaccagg
     7081 gagaaaaagg ggacgttcgc gcccttccaa tgaagaaatg gttcaacact aactaccact
     7141 acatcgttcc taaatttgaa aaagacactc aagtaaaatt ggctggtcac aagattttcg
     7201 atgagttcca agaagccaaa gaacttggat tgaacactcg tcctgttctt gtaggtccct
     7261 tcactttcct tcaattgtca gactttgaag aaggcgtgaa agcagacgac ttcgtagata
     7321 gcttagtggc tgcttaccaa gaagtttttg ctaaattggc tgaacttggt gcgactcgca
     7381 tccaattgga tgaagcggct cttgtaaaag acttgacagc tgaagaaaaa gctctcttct
     7441 tgaaccttta caacaaactc ttggctgaca aaaaaggtct tgaagtcttg cttcaaactt
     7501 atttcggtga tgttcgtgac gtatacgctg accttgtaaa cttaccagta gatgctatcg
     7561 gtcttgactt tgttgaaggt aagaaaactc ttgaactcgt taaaggtggc ttcccagctg
     7621 acaagactct ctatgtaggt attgtcaatg gtaaaaacat ctggcgcaac aactacgaaa
     7681 agagcttggc tgttcttgag caaatcccag ctgaaaacat cgttttgaca agctcttgct
     7741 cacttcttca tgtgccattt acaactgcta atgaagaatt tgaaccagca ctcttgaacc
     7801 actttgcctt tgcagttgaa aaattggatg aaatccgtga cttggatgct atccgcaatg
     7861 gtcaaggttc agaagctctt gcagccaaca aagaactctt tacgactgag cgtgttggtg
     7921 aaaatgctga acttcgtgcg cgtatcgctg gcttgacaga cgcagactac actcgtttgc
     7981 cagtctttgc agaacgtgaa gctatccaag aagaagcttt caaacttcca gctcttccaa
     8041 caacaacgat tggttcattc cctcaaacaa aagaagttcg tgccaaacgt ttggcttacc
     8101 gtaaaggtga attgtctcaa aaagagtacg atgctttcct tgctgaaacg attgacgaat
     8161 ggatcaagtg gcaagaagat attgactttg atgtccttgt tcacggtgaa tttgagcgta
     8221 atgacatggt tgagtacttc ggtcaaaact tgtcaggata cctcttctct aaaaatggtt
     8281 gggtacagtc atacggtatg cgtggggtga aaccaccaat catctggggt gatgtcactc
     8341 gtcttaaccc tatcactgtt aaatggtcta gctatgcaca aagccgtaca aacaaacctg
     8401 ttaaaggtat gttgactgga cctgttacca tcctcaactg gtcattccca cgtgaagaca
     8461 tctctatcaa ggattcaact cttcaaatcg cccttgctat caaggatgaa gtgcttgacc
     8521 ttgaagctgc tggtgtgaaa atcatccaaa ttgatgaggc tgctcttcgt gaaaaattgc
     8581 cactccgccg tagcgactgg tacgaagact accttgactg ggctattcct gccttccgct
     8641 tggtacactc aacagtagcg ccagacacac aaatccacac tcacatgtgt tactcagaat
     8701 ttacagatat catcccagct atcgataaca tggatgcaga cgttatttcc tttgaagcta
     8761 gccgttcaaa ccttgaaatc ttggacgaac tcaaagcgaa aaacttccaa acagaagtgg
     8821 gacctggggt ttacgatatc cactcacctc gtgtaccaaa tgaaggcgaa atcgacaaca
     8881 caatcgaagc catccttgct aaagtgccaa gcaagaaagt ttggatcaac cctgactgtg
     8941 gtttgaaaac acgtggtatc ccagaaacaa aagaaagctt gatccgcctt gttgaagcag
     9001 ctaaagctgc gcgtgagaaa ttgtaagatt ggatttctct ccatacagtg gttgttcaaa
     9061 aagaaatcaa ctagaaaagg ttattacata tgtcacgcca aacaccgtca ctctcatttg
     9121 aagtgttccc tccaaaccca gccgtgggta atgataacat tatttcagcc ttgcaggata
     9181 tgcaggagtt ggttccccat tttatcagtg taactgccag caataataaa tttaatatca
     9241 aggaaacgac ggttcgtttg gctgacttta tccaaaatga tttggcgatt ccgaccattg
     9301 cccacttgcc agctatttat ctaactaagg acaaggttgc tgaaactatt gctgacttgg
     9361 acaaagttgg ggtgcagaaa atcttggctc ttcgtgggga tattattcca gacgtggaac
     9421 cacaaaagga tttccgctat gcaaccgact tgattgagtt tatcaaggaa cgagcccctc
     9481 actttgatat tattggagct tgctatccag aagggcatcc agattcgcca aatcagattt
     9541 cagatattca aaatcttaag aagaaagtgg atgcaggctg ttcgagcctc gtaactcagc
     9601 tcttctttga caatgagcgc ttctatgatt ttcaggacaa gtgtatcttg gctgggattg
     9661 atgttcccat tcatgcagga attatgccaa ttctgaatcg aaatcaggct ctccgactct
     9721 tgaagacttg tgagaatatc catcttccac gcaaatttaa agccatctta gacaagtatg
     9781 agcatgaccc tgagtcgctc agagcagcag gacttgccta tgcagtggac caaatcgtgg
     9841 acttggtaac tcaggatgtt gccggtgtgc atctctatac gatgaataat gctgatacag
     9901 caaaatacat ccatcaagca acccatgcct tgtttaatca ccagtctcta ggataataaa
     9961 agcaaaccat tcttctcagg tgaggggaat ggttcctttt taatggtaaa gacctcactt
    10021 tttaagaaaa atatgataaa ataaattctg tacgtacttg atacaaagat gaaggtatta
    10081 aataatacaa tgcatttaaa ctgtaagatt taacgacacg agtgagtcaa atcgatgtta
    10141 tttgacgaga gagttagtaa agcatttagc taatcgcccg atagcgatta gcgtgaaagc
    10201 tttagatact ttagtattaa acctttctaa tgatgtatct tgaaaactga acttgcctac
    10261 aactctgtgg aaaaagataa atctccctag gagtagtcgc tccgtcgttc gatttcctat
    10321 cttcctttga gttgcttgac ggcttggtat cttgatgact tgaattttgg tctcatttct
    10381 taggaaaaaa gataagcttc ctagcactcg tcgagtgtga cgtcaccttc ctatttttct
    10441 acagaaatgt tcggcaagcc gaaccgtcca aaatatcttg tgtaattgaa cacggccgaa
    10501 aagctgtgta aaaaagataa actgtcttgt cttcatcgaa gacttcgtca gtttcctatt
    10561 tttactttgc ttttgacgtc cttggtatct tgatctttgt aggcaaggcg tataatttca
    10621 tcaatccaaa ggggattaaa atggcaaaac aagtgtttca aacgactttt gcgggtcgtg
    10681 agttaattgt agaaactggt caggttgcta agcaagcaaa tggctctgtt gtcgtacgtt
    10741 acggtgagtc aactgtcttg actgctgccg ttatgtctaa gaaaatggca actggggatt
    10801 tcttcccact ccaagtcaac tacgaagaaa aaatgtatgc ggctgggaag tttcctggtg
    10861 gctttatgaa acgtgaagga cgtccttcaa cagatgcgac cttgacagcg cgtttgattg
    10921 accgtccgat tcgtcctatg tttgcggaag gtttccgtaa tgaagtccaa gtcatcaata
    10981 cagtgctttc ttatgatgaa aatgcatctg caccaatggc tgctatgttt ggttcatctt
    11041 tggcactgtc tatttcagat attccatttg acggaccaat tgctggggta caagtgggat
    11101 atgtagatgg ccaaatcatc atcaacccaa gtcaagaaca agcagagcaa tctcttcttg
    11161 aattgacagt agctggaacc aagcacgcta tcaacatggt agagtctggt gccaaagaat
    11221 tgtcagaaga aatcatgttg gaagcgcttc ttaaagggca cgaagctgtc aaagaattga
    11281 ttgccttcca agaagaaatc gttgctgctg tcggtaaaga aaaagcagaa gtggaattgc
    11341 ttcacgtgga tgctgaattg caagctgaaa tcattgcagc ctacaacagt gacctccaaa
    11401 aggcagttca agtagaagag aaattggccc gtgaagctgc aactcaagca gtgaaagacc
    11461 aagtgactgc cgtttacgaa gaaaaatatg cgaaccacga agaatttgac cgtattatgc
    11521 gtgatgtggc tgaaatcttg gaacaaatgg aacacgcaga agtgcgacgt ttaattacag
    11581 aagacaaggt gcgtcctgat ggtcgtaagg tcgatgaaat ccgtcctttg gatgcggttg
    11641 ttgacttcct tcctcgtgta catggttcag gtctctttac tcgtgggcaa actcaagctc
    11701 tttcagtctt gaccttggct ccgatgggag aaactcaaat cattgatggt ttggatccag
    11761 agtacaagaa acgctttatg caccactata acttccctca atattctgta ggggaaacag
    11821 gtcgttacgg tgcgccaggt cgtcgtgaaa tcggtcacgg tgcccttggt gagcgtgctc
    11881 ttgctcaagt cttgccaagc ttggaagaat tcccatacgc tatccgtcta gtagcagaag
    11941 ttttggaatc aaacggttct tcatctcaag cttctatctg tgcgggaact cttgccctta
    12001 tgactggtgg tgtgccaatc aaggcgccag tagctggtat tgctatggga cttatctcag
    12061 atggaaataa ctacacagta ttgacagata tccaaggttt ggaagatcac tttggagata
    12121 tggacttcaa ggttgcaggt actcgtgatg ggattacagc ccttcaaatg gatatcaaga
    12181 ttcaagggat tactgcagaa atcttgacgg aggctcttgc tcaagccaag aaagcgcgtt
    12241 ttgaaatcct tgatgtcatt gaagcaacca ttccagaagt tcgtccagaa ttggctccaa
    12301 ctgctccgaa aattgatacg atcaagattg atgtggacaa gattaagatt gtcatcggta
    12361 agggtggaga aaccatcgac aagattatcg ctgaaacagg tgttaagatt gatatagacg
    12421 aagaaggaaa tgtgtctatc tactctagtg accaagatgc tattaaccgt gccaaagaaa
    12481 ttattgctgg tttggttcgt gaagccaaag tggatgaagt ttaccgtgct aaagtcgttc
    12541 gtatcgagaa atttggtgcc tttgttaacc tctttgataa gacagatgcc cttgttcata
    12601 tctctgagat ggcttggact cgtaccaatc gtgtagagga tttggtagaa atcggggatg
    12661 aagttgatgt taaggttatc aagattgatg aaaaaggccg tatcgatgcc tctatgaagg
    12721 ctcttctacc tcgtccgcca aaacctgagc atgatgaaaa aggtgaaaag tctgagcgcc
    12781 ctcaccgccc acgtcatcac aaggatcaca aacctaagaa agaatttaca gaaacaccaa
    12841 aagattcaga gtaagaaaag gagaaatgta tggggtggtg gcacgaaacc attgatatcg
    12901 taaaagaaaa tgatccagcg gcccgcacca ctttggaggt tttgctgact tatccaggtg
    12961 tcaaggcctt ggcggcccac cgtctctcgc attttctctg gaagtacgac ttcaaactct
    13021 tagctcgtat gcacagtcag ttttggcgct tttggactca gattgagatt catccaggag
    13081 cccagattga ttcaggtgtc tttattgacc atggttctgg tctggtgatt ggagagacag
    13141 cgattgttga aaaaggcgtt cttctctatc acggagtgac tctcggggga acagggaaag
    13201 actgtggcaa acgccatccg actgtacgaa agggagccct catatcagcc catgcccaag
    13261 ttatcgggcc tgtggaaatt ggtgaaaatg ccaaggtcgg tgctgcagca gttgtcgtag
    13321 cagatgtacc tagtgatgtg acggttgtcg gtattccggc caagattgtc cgtcttcatg
    13381 gtaagaaaga tgagcctgtt attcacgaag tcgaagaaaa acgggagtat tatgtcaata
    13441 aactcgagca ggctaaagat gccagtcaca gatcgtctgg tttgtagagg atacctatat
    13501 gattcaagca agaaacaagt taagccaaga ggagctatct gaggcgaaaa aagtaattaa
    13561 ctgttgccaa aactatgacg gtacctatcg cgatccctat ctctctaaca tgcttaattt
    13621 tgacccaaac atgcccgcct ttttccttta ttatgaaaaa ggcaaacttg ttggtttatt
    13681 aactgtctat gcagatgacc aagatgtaga agtgacgata ttggttcatc caggtcatcg
    13741 ccgtcagggg attgcgcgtg cattgtttac tagttttgag agagaaacag cttctttccc
    13801 cattcggtca gtcacttttc agacagaacg tattttttta gagaatcatc ctgactttgc
    13861 cagtaactgg ggactaatcg aggatgaaga gacagaaact tggttaggta aggatagaag
    13921 accttatccg ttagcaaatg tttcccatct tgaagttttg ttagcagata gttcgtatca
    13981 ggatcaaatt agtcaattaa aatttcaggc attttcagag gaacatgaat cgagagaagt
    14041 tgtggataga tatgtcgctg aagctctgaa ggatccagaa agtcgcttat atattttgtt
    14101 aaaagacggt caggttattg ggacttgcac ggtagattta tcgactaata cgaattactt
    14161 ctacggttta gcaatatcgg aacctgaacg tgggaaaggc tatggaagct acttagcaaa
    14221 atccctcgtc aaccaactaa ttgagcaaaa tgacaaggaa tttcagattg cagtggaaga
    14281 tagcaatgta ggtgccaaac gtttgtatga aaaaattggc tttgtcaaac agacacaggt
    14341 ggtttatctg aatgagaaag gagcaaggga ttccgaagtg tagagacatt cggactgaaa
    14401 tttacttgag ctcttagttt agtgatgaaa ctaacagttc ttggatttta gctttcctga
    14461 ttatgattta tgattaaaat ctatgacacc atgtctcgtg atttgcgaga atttgtcccg
    14521 attgaggacg gcaagatcaa gatgtatgtt tgtgggccaa ccgtgtacaa ctatattcac
    14581 gtgggaaacg cccgttcgac ggtagctttt gatacgattc gtcgctattt tgagtaccgt
    14641 gggtataagg ttgcctatat ttccaatttt acagatgtgg atgataagat tatcaaccgt
    14701 gccagggaag aaggcatcac acctcaggag gttgcggata agtacatcgc tgcctttcgt
    14761 gaggatgtga cggccttagg cgtgaaacct gcgactcgcc atccgcgtgt agtggagttt
    14821 atggcagaca tcatccgttt tgtggaagac ttgatcgaga aaggctttgc ctatgagagt
    14881 caaggggatg tctatttccg tgtagaaaaa tcccacaact atgctaaatt ggctaataaa
    14941 accttggaag atttggagct aggtgcttca ggtcgtaccg atgaagaaac ggctcgtaag
    15001 gaaaatcctg tagattttgc tctatggaaa tcttccaaac caggtgagat ttcttgggat
    15061 agtccttggg gacctggacg tccgggttgg catattgagt gttcagtcat gtcgacagag
    15121 attttaggtg ataccattga tatccacggt ggtggagctg acctagagtt tccacaccac
    15181 accaatgaaa ttgcccaatc tgaagctaaa acaggcaagg cttttgctaa ctactggatg
    15241 cacaatggct ttgtcaatat cgacaatgtc aaaatgtcta agtccttggg taacttcatt
    15301 acggtacacg atgcccttaa aactcttgat gggcaagtac ttcgtttctt ctttgcgacc
    15361 cagcactacc gtaagcctat caacttcacg gaaaaggcag ttcgcgatgc cgagaccaat
    15421 ctcaagtatc tgaagaatac ttacgaacaa ccatttacag gaaacgtgga tgcccaagag
    15481 ttacaaaact ttaaagataa gtttgtagca gctatggatg aagattttaa tgctgccaac
    15541 ggtatcacag ttgtctttga aatggccaaa tggatcaact cagggaacta tgatgcaagt
    15601 gtcaagcaag ctcttgcaga tatgttagaa atttttggaa ttgtctttgt tgaggaagtt
    15661 ttggatgcag agattgaaga cttgattcaa aaacgccaag aggcgcgtgc caatcgagac
    15721 tttgagacag cagaccaaat ccgtgaccaa ttggttactc aaggaattaa gctccttgat
    15781 accaaggatg gagtgaggtg gacacgtgat tgatgtcaat ctcattaacg ggattgcgct
    15841 agcctttgag ggggatgcgg tgtattctat gtatattcgc cgtcacctca tcctcaaagg
    15901 tatgaccaaa cccaataaac tccatcaaga agcaaccaag tatgtgtcag ccaaggctca
    15961 ggctcgcctg attgctctca tgttggagga gcaggtccta acggaaaaag aagaagaaat
    16021 ctacaaacgt ggccgcaata ccaatagcca cacaaaggct aaaaatgcag atgtcgtgac
    16081 ttatcgtatg tccacgggat ttgaagcggt tatgggctat ctccatatga ctgagaatct
    16141 ggaacgtctt gagagtttgg tttcatggtg catccaaaaa gtggagggct agaacatgag
    16201 ggaaaaagaa ctacaagact ggtttcctga ggctcggatt tcagaccaac cagtagagaa
    16261 agagggctat ctcacgctcc ctttagcttc tcagcagtgg attttgctgg aggaagctgg
    16321 gctcagcgag cgtgaaaagc agttggttgc ccttttgacc cagcaggagc aggctcgttc
    16381 gctaaaccct tggtattcct atctggttga aggcaaggga caggcaccgc aagtttttaa
    16441 aaagattcag ttggtttatt gccatctttc ttattttcag caggaaaatc tggcttcttg
    16501 gctagatatg atgcggactc tttttccgaa ttgtcagaca gtgctacagg tcggagctca
    16561 ggattatgtt ttcgtgcttc aacaagacaa atacacttct gtaagagata ttttaagtga
    16621 tacgattgaa gcggttgagt atgactttgg acttcgtctt tctatcatgt tgggtcaggt
    16681 ttggtctcag acaggacatc aagccctatc agacttaatc aaagctgagc gggatttgtt
    16741 caagacatgg tggcgtcagg gtcaccaagg tgttcatact ttttctcagc tctatctttg
    16801 gagtatggga gaaagactcg tggacttgaa gccaattaaa gaatgtctac accagatgat
    16861 tttggatcaa gatcagattc aggaaatcat tctctctctt tgggaaaata gtgctgttct
    16921 cactaaaaca gcccagcaac tctatctgca ccgcaattct ctccaataca agattgataa
    16981 atgggaagag ttgacagggc ttcagttgaa agagttgacc gacctgacct tgtgttatca
    17041 attgatttta ggttctttgt caactatagt tggtttgtaa agaagttaat atttggagaa
    17101 gaggattgcc atcttctcca ttt
//
LOCUS       DAVKMJ010000042        16803 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000042 DAVKMJ010000000
VERSION     DAVKMJ010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16803
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.042"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..1133
                     /locus_tag="VW348_001651"
                     /pseudo
     CDS             1..1133
                     /locus_tag="VW348_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1321..2883)
                     /gene="guaA"
                     /locus_tag="VW348_001652"
     CDS             complement(1321..2883)
                     /gene="guaA"
                     /locus_tag="VW348_001652"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEU9746525.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            3025..3723
                     /locus_tag="VW348_001653"
     CDS             3025..3723
                     /locus_tag="VW348_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEU9746526.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERHVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(3766..4662)
                     /locus_tag="VW348_001654"
     CDS             complement(3766..4662)
                     /locus_tag="VW348_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEU9746527.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQTDIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(4671..5606)
                     /locus_tag="VW348_001655"
     CDS             complement(4671..5606)
                     /locus_tag="VW348_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEU9746528.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLSQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(5603..6328)
                     /locus_tag="VW348_001656"
     CDS             complement(5603..6328)
                     /locus_tag="VW348_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEU9746529.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(6412..7047)
                     /locus_tag="VW348_001657"
     CDS             complement(6412..7047)
                     /locus_tag="VW348_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEU9746530.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(7049..7876)
                     /locus_tag="VW348_001658"
     CDS             complement(7049..7876)
                     /locus_tag="VW348_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEU9746531.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKVRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDIIQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(7898..8233)
                     /locus_tag="VW348_001659"
     CDS             complement(7898..8233)
                     /locus_tag="VW348_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HEU9746532.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(8234..8950)
                     /locus_tag="VW348_001660"
     CDS             complement(8234..8950)
                     /locus_tag="VW348_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEU9746533.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWFKQADLAIG
                     DFEETINKDHYLAGYPLFNAPAEVMDAIKEAGYHVLDLAHNHILDSQIEGVISTADII
                     EKAGITPIGVYTHEPRDQAPLVIKEVNGIKVALLAYSYGFNGIEQYISQEDYNRYLSD
                     LNEDKMKAEIERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHL
                     YVVEPSETIEKDGDKKLIVY"
     gene            complement(9093..9284)
                     /locus_tag="VW348_001661"
     CDS             complement(9093..9284)
                     /locus_tag="VW348_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746534.1"
                     /translation="MKEILICDIIKRKGLHKKVGRMKMQRRQNRNQGGLAFRFMKGLV
                     NFLGVIASGAIRDLWRYSC"
     gene            9473..10084
                     /locus_tag="VW348_001662"
     CDS             9473..10084
                     /locus_tag="VW348_001662"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEU9746535.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEGIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            10129..10857
                     /gene="rlmB"
                     /locus_tag="VW348_001663"
     CDS             10129..10857
                     /gene="rlmB"
                     /locus_tag="VW348_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEU9746536.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKNLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENSLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(10896..11807)
                     /gene="trxB"
                     /locus_tag="VW348_001664"
     CDS             complement(10896..11807)
                     /gene="trxB"
                     /locus_tag="VW348_001664"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEU9746537.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVRKIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(11873..12097)
                     /locus_tag="VW348_001665"
     CDS             complement(11873..12097)
                     /locus_tag="VW348_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEU9746538.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTAKARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(12175..12918)
                     /locus_tag="VW348_001666"
     CDS             complement(12175..12918)
                     /locus_tag="VW348_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9746539.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(12918..13718)
                     /locus_tag="VW348_001667"
     CDS             complement(12918..13718)
                     /locus_tag="VW348_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9746540.1"
                     /translation="MNVTTILASDWYQNLMQLIPNGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(13876..14232)
                     /locus_tag="VW348_001668"
     CDS             complement(13876..14232)
                     /locus_tag="VW348_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEU9746541.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(14226..14756)
                     /locus_tag="VW348_001669"
     CDS             complement(14226..14756)
                     /locus_tag="VW348_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEU9746542.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRSNRRRSTC"
     gene            complement(14756..15250)
                     /locus_tag="VW348_001670"
     CDS             complement(14756..15250)
                     /locus_tag="VW348_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9746543.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            15385..15831
                     /locus_tag="VW348_001671"
     CDS             15385..15831
                     /locus_tag="VW348_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEU9746544.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            15828..16475
                     /locus_tag="VW348_001672"
     CDS             15828..16475
                     /locus_tag="VW348_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEU9746545.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILTASVLQYIAIVYYM"
BASE COUNT         5058 a         3790 c         2972 g         4983 t
ORIGIN      
        1 tctaaaattc cttatcttga aacgactggt atgccttcta gaattctcct tagaaaacgc
       61 cgtttcaagt gctatcactg ttcaaaaatg atggttgctg agactcccct ggtaaagaag
      121 aatcaccaaa tccctcgtat catcaaccaa aaaattgctc aaaagttaat tgaaaagatt
      181 tctatgactg atattgccca tcagctttcc atctcaactt caactgttat tcgtaagctc
      241 aatgattttc actttaaaca tgatttttcg cgtcttcctg agattatgtc ttgggatgag
      301 tatgctttta caaagggaaa gatgagcttc attgcgcaag attttgaaaa gctcgatatc
      361 atcactgttc ttgagggtag aacacaagct atcattcgaa atcactttct tcgctacgat
      421 agagttgtcc gatgtcgcgt caaaattatt actatggata tgtttagccc ttactatgac
      481 ttagctagac agcttcgctt tcaaatttct aggctcaggc tgaaacagtc tcccagactg
      541 tttcactccc gaatgctaaa atcgttcttg atcgctttca cattgtgcaa catcttagcc
      601 gtgctatgag tcgtgtgcat gttcaaatca tgaatcagtt tcatcgaaaa tcccatgaat
      661 acaaggctat caagcgctac tggaagctca tacaacagga tagccgtaaa ctgagtgata
      721 agcgttttta tcgtcctact tttcgtatgc atttaaccaa taaagagatt ttagacaagc
      781 ttttgagcta ttcggaagac ttgaaacacc actatcagct ctatcagctc ttgctttttc
      841 acttccagaa taaggaacca gagaaatttt tcggacttat tgaggacaat ctgaagcagg
      901 ttcatcctat ttttcagact gtctttaaaa ccttcctcaa agataaagaa aagattatca
      961 acgcccttca actaccctat tcaaacgcca aattggaagc gaccaataat ctcatcaaac
     1021 ttatcaagca caatgccttt ggttttcgga actttgaaaa cttcaaaaaa cggattttta
     1081 tcgctctgaa tatcaaaaaa gaaaggacga aatttgtcct ttctcgatct tagcttttct
     1141 tcaacccact acagttgaca aagagcctga aaactacggt ctaatttttt gtccaaatgt
     1201 aaaccacttg gaactattat tcaatttatt ctttttagca aatgttcccg ttttaatccc
     1261 agttacagtt tttaatcctt tgtaaccgtt gattttacaa agcttttaat ttttttgcga
     1321 ttactcccac tcaactgttg caggtggttt acttgtaata tcgtagacga tacggttaac
     1381 atgatccact tcatttacga tacgtactga gattttttga agtacttccc atggaatttt
     1441 ggcaaaatca gcagtcatac catcgataga agtgatagca cggattgcaa tcgtgtagtc
     1501 atacgtacga ccgtcaccca taacaccgac tgaacgaacg cctgtgttaa cagtgaagta
     1561 ttgccaaata tcgcggtcaa gtccagcttt agcgatttct tcacgaagaa tagcgtctga
     1621 ttcacgaacg gtttcaagtt tctcttcagt gatttcaccc atgacacgga tagcaagtcc
     1681 tggtcctggg aatggttggc gccatacgat atggtctggc ataccaagct ctgtaccaag
     1741 agcacgaact tcatccttgt aaagagtatt gagtggttca atcaattcaa actgcatatc
     1801 ttctggaaga ccacccacgt tgtggtgtga cttgatagtt tgagctgtat ccgtaccaga
     1861 ctcgataaca tctgtatata aagtaccttg agcaaggaat ttcacatctt tgagcttgct
     1921 tgcttcgtca tcgaatacat agacaaactc gttaccgatg attttacgtt tttgttcagg
     1981 gtcagaaacg ccagcaagtt tgtcaaggaa acgtttagca gcgtctgctt tgacgatatt
     2041 caaaccaaac ttaccaccga gcatgtccat aacttgatca gcttcgcctt tacgaagaag
     2101 accgtggtcc acgaagatac agatcaattg atcgccaatc gctttttgga gaagaacccc
     2161 aacgacagat gagtcaacac cacctgatag accaagaagg acacgtttat caccgacggt
     2221 ttcacgaatt tttttgatct gcatgtcaat gaaattatcc attgaccagt cacctttagc
     2281 cttacaaatg ttaagggcaa agttacgaag gatatcattt ccgtatacag aatgacgaac
     2341 ttctgggtgg aattggatac cgtaaatgtg tttatctggg ttttcgatgg ctgcgtatgg
     2401 gcagtcagct gatgtacctg tacgaacaaa gtcagcagga atctcagtaa ccgcatcacc
     2461 atggctcatc aaaacagtct gttcatcagg tgttgattca aaaagcgctg atggtgtgtg
     2521 agttagggtt gattgaccgt attcacgatt tccagcatca cctgcaggaa caacttttcc
     2581 tccaagttta tgggtcaata actgcatacc ataacagatt cccaaaattg gaattccgag
     2641 ttcgaagatt tctgggtcaa tatcaaatga accatcttca tatacagaat ttggaccacc
     2701 tgatagaata attcctacag gattgacttc acgaacttca gcagctgaaa ttttatggct
     2761 ttttagttct gaaaaaacac caatctcacg gatacggcgt gaaatcagct ggttgtactg
     2821 gctaccatag tccaatacga tgattttttc tacatcttgc aaatcagttg aaatgttgct
     2881 catctttttc ctttctcaaa agaaatatct tttctcaata ttctatcaca aataagggcg
     2941 aattaccaac taaacaaggc gaagtttgac tttttctagt ttattggggt acaatagaga
     3001 aaagatagaa atgaagtgaa aaatatgcta cctgcttata tgaaaatcca tgatcagata
     3061 aaaaaggata ttgacgagca ccgttgggct attggtgaga ggcttcccag tgaaagagat
     3121 ttagctgagc agtttgcggt cagtcgcatg accctccgcc aagccgtatc tctattagtc
     3181 gaagaaggcg tcttagagcg ccatgtagga agcggcacct ttgtttccag tactcgagta
     3241 caagaaaaga tgcgagggac aaccagtttt actgaaattg tcaaatccca aggtaaagtt
     3301 ccctctagcc agctcatttc ctacaaaaaa accattccca atgagcaaga agttgccaag
     3361 ctaggaattt ttccaacgga caatattatc cgaatggagc gggtccgcta tgccgaccaa
     3421 gttcccctag tttatgaagt tgcttctatt cctgaaaaat tcattaagga ctttaaaaaa
     3481 gaagaaatca ccagtcattt cttccaaacc ttgcaaaaac atggctatcg tatcggcaaa
     3541 tctcaacaga ccatctatgc tcgccttgct aaagaaaaga ttgcccacta tttggaagtt
     3601 gaaaaaggac atgctattct tggattgacc caggtttcct acctagaaga tggtactgct
     3661 tttgaatacg taaaaagtca atatgtaggc gaacgctttg aattttatct tgaaaataat
     3721 tagattacca cgcaaaaact ctctgtcacg gacaaagagt cttttttatt tttctaagaa
     3781 taaatctttc aaagaaatca aagttacagc aaacaatatc attgccatac caagaaaatc
     3841 aatgggataa aattgttcat tcattattaa gaaggcaaag aaaatcgccg atattggctc
     3901 aattgaagcc aacaagcttg acttgaccgg tcctatcaga ctggctcctt taaggaaagc
     3961 tgtataggca aagacagtcc cgataaggat aatgcctgca aacgcaagga gaaaatcaag
     4021 actagtcggg atatcggtct gtagaacccc tgtaaaagga agggcgacca aacctgctat
     4081 gaccattccc acaccaatga ccaagctgct cccccacttt ttaatcaagg ctatgggtaa
     4141 aatgatatac agagcataag tcaaggcaga aaagagaccc cagaacagac cagcaggtgt
     4201 catggataac tggtccaact gcccatgtgt tgcgatcagg aaggttcctc cgatggcgaa
     4261 tatgatggaa actatctctc ccagtgtcgg tgccacccta tccttgatac agctataaat
     4321 taaaattccg acaggacaaa catactgaag caccgtcgct gttcccgcat tggtctcctg
     4381 aatagcagac agataggcga attggttgag aaaaagacca atcagagcaa aaataagaag
     4441 agacagcaaa ctctttctat cctttaaaaa gaccagtatt ttatcctttg cagtagcata
     4501 agccaagagc atgagaattc caccagcgat taaaagacgc aagttggtca agaccagagc
     4561 cgaaattccg tgtgccatta ggtattggcc actcgttcct gacaaccccc aagcaatacc
     4621 agccacaact gttagtaaag tcccttttaa actatttgac atgtctctcc ttactcttct
     4681 ttgcgaatca agttcatcac ttgattgcgg tctaatatcc attgagctct ctcgtccttt
     4741 tcataggtac gattcgatag gaaaatagtg gcttcttgct tctgacgatt ccacatgata
     4801 aaggtacctg tatagcccgt atggtctagc caatctcctt ccaaattcca tgctaaagaa
     4861 cgttccttgt catccaaagg agaaaaattt tgacttaagt ctcttgcaaa atcatctgct
     4921 aaatagtgtt ctaaaaagat ttgtaaatcc tttatagtcg aaaataaacc agcgctccca
     4981 gcatgtctac ccaggagacg agccttggga tcatgcacta tgcctgcctc tacacctcta
     5041 actgttggaa cagcaagctc aactggccca aacttggttt ccgtcattcc ccaaggtttc
     5101 cagacttgat cctttaaaat cacatccaaa tcttgattaa aaattctttc caaaataaag
     5161 cccaacagca aaaaatggac atccgaataa agaaaggctg gctgacttcg tctgttgaga
     5221 tgaaacatcg cttcctttaa ttcaggggct gttaaaagat cacgattagg aataaaagga
     5281 tcaaggtctg ttgcatgagt caagagctgg cgaatagtga tgtctggata atcactctca
     5341 ggtaaaaaat ctattaccag tctatcaata tctaattgac ctatttccca caagaaggta
     5401 caaactgtgc caaccccaac aaccttgctg acactagcta ggtcataaac tagtcctgcc
     5461 tcagtctgca agccatgctc tgggtcactc tggcctaaat agaactctgt ccattgattg
     5521 tccttaaaat acgcaaaaga ggctccggga taaattcctg cctcgatttg ttcttctatt
     5581 tttttaataa tcttggtcca cttcatactt cttcaaacca caattcaaca ttatttctat
     5641 ctttacaaag gaagaatttt tcagacttag gaataaaata ttcagtagac tcaaacttct
     5701 ggcgaagact tgctatgtct aattcattga ccaagaactt gagcatagat aagtcccagg
     5761 taaccgtatt gtccacagtc aaatcctgcc cctgagctgg aataaaatca agggatgccc
     5821 caatttcaga tgattccaag aaactttcga tatcagttgg gagatgtaat tccatagaaa
     5881 tctcaaattt acttaaagaa attgatgcca aatctgtttg aaattcaggc ttttctccta
     5941 cttctactag acttgctctg tcatcttccg catgaatcaa aatcaaatca tcttctggtg
     6001 agaaaatttc aaaagcgtag ccattttgac ctttatataa tcgatgaatc gaatctgttt
     6061 tagataagat tccttcaatt tctaagggat tttccacctt gacaatcaat ctagctagtt
     6121 tttttcttcc ctctacctta cgagtacgca tactgggagc ttcttctaaa accagctttt
     6181 caagacccgt ttggtcacct agtgacagaa aggccgattc ttctaacaag gccttcattc
     6241 caagggtttc aatataaaat gtttcattta attttctatt attagctttt aaagtaggaa
     6301 taatccgtac aatctgattt acattcataa attcctccgt cactttttat tttaaaggat
     6361 tttagaattt tttacaagat attatgctca aatttaacat tatttagcta tttagtaaag
     6421 atagtctttc aaggattttg acaaagcctg ataaccagca atactgaggt gcagtccatc
     6481 agttgtatat tcttttttga gttggcctgc ttggtctgtc aaacaatcaa atactggcac
     6541 aaattccacc tgcatatagg cagatgcaag ctcttgatag gcttgattcc agttctgaat
     6601 tttttcattc gagcggatat agactgcctg ctggtactcc tctccctcat tgacaggcaa
     6661 aatggaaagc aatttaatct ctgtcaatgg ataatcgcga gcaacggatt gaatgatagc
     6721 ttcgagatta ttgagagcct cattcacagg aacatccttt ccgatatcat ttgtcccaat
     6781 cagaagaaaa attttatcta ctgctccacc atatagatga gcatcaagat tctctagtaa
     6841 cagtcctgtc tgatagccac gaattcctcg attgacaatc gtctttgaag tcccaaatag
     6901 ctcctgtaga ggataatact cgacaatgga atccccaata aaaagaatgt ttggttctac
     6961 aacagaaatg tgatttaggt gacgatactt agtttgaatt ttttcttgtt cctttaggag
     7021 ccaattttct aataactgta ctgccacttc attctccttt ttctaaccag ttttccaaga
     7081 cttgataaac tcctccttgg ctgttggctg gtgctagagc agtcgccaca gctttggctt
     7141 tctcatcagc attttccatc gcataggcaa ttccagccat ttcaagcatt tcaacatcat
     7201 tttcactatc accaaaagcc atgatttctt gggatttcaa gtcccagcgc ttgagtaatt
     7261 cctccaagcc ccatgcttta tgaatcccag cttggatgat atcaatgcaa ccatagccac
     7321 tggatacagc tcggacacgg ccatcaaaga gagcattgat ttcttccaaa accgaactca
     7381 aacgttcctc accaacaacc atgctcatct tgagcacacc accaaagagg tcagatgtta
     7441 attcatccac aaattgcatc cgttggtaga atttttcaat catttctgga gtcataaaac
     7501 tttcaagatc tgtaaaaatc gtaccttcct tgacaaaatc acccttcatc cccgttacaa
     7561 caaactggtc ctgacacgct cgaaccttga aatgagtcaa agccttgttg acaatggcgt
     7621 catcccatgt ctgagcctga atcaattcat tgttttcaaa aatacgagcg ccattagcaa
     7681 caaccagaac cactcgatcc accaagggac tcagtagttg tctcatgcgg tgaatttcat
     7741 tgcccgtcgc aatgacaaaa cgaatgcccc tttgatccaa ctgatctaaa atcttttcca
     7801 atcgtgggag atcaagctga cctctagcat ccagcaaggt cccatccata tctgtcgcaa
     7861 ttaccttaat catcatttac tttcctctgg attcaagcta ataccacttc aatcccacat
     7921 gttcattcat ttctttatag gctgtatcaa ttcgttcctt agtcgcttca tctaactggt
     7981 cacgatgact gccatcctct ataaaatctt ccaaaatata agtttggtaa tgatacaagg
     8041 gatatccttc tggtgaaaag gttccctttg gtgttcgatt gacccaagta ggatgagctt
     8101 tagctgttcc gatagttgtt tttccatcct tcttcttgat ggtgacatcc atgagaacac
     8161 cacgttcagt ccacttagca ttctcttcat ctcccataga ttcaattcgt tgattggaaa
     8221 tgaagttccc catttaatag acaatgagct tcttatctcc atctttttca atcgtttcag
     8281 atggttcaac aacgtaaaga tgccctccaa agataatatc cgctccccaa tcgatcatct
     8341 tgtgataaag agctttttgt tcttcagttg gttccaatcg atactcaaca cccatctgag
     8401 gcatgataat ggtgatatct gcttccttct ctgcccgttc aatttcagcc ttcatcttat
     8461 cttcgtttaa atctgaaaga taacgattat agtcttcctg agaaatatac tgctcaattc
     8521 cattgaaacc ataggaatag gctaacaatg caaccttgat accattcact tccttaatga
     8581 ccagcggagc ctgatcacgt ggttcgtgcg tataaactcc gattggagtg attccagctt
     8641 tctcaataat atcggccgtt gaaataactc cctcaatttg cgaatccaaa atatgattat
     8701 gagctaaatc cagcacatga taacctgcct ccttaatagc atccataact tcagcaggag
     8761 cattaaagag aggataaccc gctaaataat gatccttatt aatggtttct tcaaaatcac
     8821 caatagctaa atctgcttgc ttgaaccaag gagtcacata ctcaaaattt tcatgaaagt
     8881 cataggtacc gtcttctttt ttagctgaaa agaaaagtcc atcgtggtag agcaaatccc
     8941 cgtgggccat aattctggca gttttttcct cttcctactc ctgagacttt tgcttagttc
     9001 cctcttgaga aatagtatct cgtttttgac tagtcaagag attccttgga agctttcaaa
     9061 caataagacc aagcccattg ataaaccaac tgctagcaag agtatcgcca caaatccctt
     9121 attgctccac ttgcgataac tcctaaaaag tttaccaagc ccttcataaa acgaaaagct
     9181 aaaccaccct gatttcgatt ttgtcttctt tgcatcttca ttctccctac tttcttatgc
     9241 aagccttttc tttttattat atcacagata agtatttctt tcacaattga attgaacttc
     9301 ccatctattt tctataaatc ctaaatgcca taatgctttc aattcttgtc attttgtgat
     9361 atcatgtaga ggtaatgaaa ggaaatgaac taatccacag tggcttattc caagtatacc
     9421 acttgggctt tggcagtagt taactgcact aaacataata taaggagaga aaatgtctgc
     9481 aatagaacgt attacaaaag ctgctcactt aattgatatg aacgatatta tccgtgaagg
     9541 gaatcctact ctacgcgcga ttgctgagga agtcactttc cccctatctg accaggaaat
     9601 catcctaggc gaaaagatga tgcaattcct taaacattcc caagatcctg tcatggctga
     9661 aaaaatggga ctccgcggtg gtgttggact ggctgctccc cagttagata tctcaaaacg
     9721 cattatcgct gttttggtac ctaatattgt tgaagaaggc gaaactccac aggaagccta
     9781 cgatttggaa ggcattatgt acaatccaaa aatcgtctct cactctgttc aagatgctgc
     9841 tcttggcgaa ggagaaggtt gcctgtctgt tgaccgtaac gtgcctggct atgttgttcg
     9901 ccatgcccgc gttactgttg actactttga caaagatgga gaaaaacacc gtatcaaact
     9961 caaaggctac aactccattg ttgttcagca tgaaattgac cacattaacg gtatcatgtt
    10021 ttacgatcgc atcaatgaaa aagacccatt tgcagttaaa gatggtttac tgattcttga
    10081 ataaagaaaa tcccgttgca agacggggtt ttgtgttata atagaggcat gaaaacaaat
    10141 gatattgtct atggtgtcca cgccgttacc gaagccctcc ttgcaaatac aggaaacaaa
    10201 ctctacctcc aagaagatct ccgaggtaag aatgttgaga aagtcaagga actagctaca
    10261 gaaaagaagg tgtccatttc ttggacatca aaaaaaaatc tctctgagat gactgaaggt
    10321 gctgttcatc aaggttttgt tctacgagtg tctgaatttg cctatagcga gctagattac
    10381 atccttgcaa aaacacgcca agaagaaaat tcacttctat tgattctaga tggtctaacc
    10441 gatccccata atctgggttc tatcttgcga acagccgatg cgaccaatgt ttcaggtgtc
    10501 atcattccca agcaccgtgc tgtcggagta actcctgtcg ttgccaaaac agccacaggt
    10561 gctattgaac acgttccaat tgcccgagta accaacctca gtcaaacctt agataaactc
    10621 aaggatgaag gtttctggac ctttggaacg gatatgaacg gtactccttg ccacaagtgg
    10681 aatacaaaag ggaaaatcgc cctcatcatt ggaaatgaag gaaaaggtat ctctagcaac
    10741 ataaaaaaac aggtcgatga aatgattacc attccgatga atggacatgt tcaaagcctt
    10801 aatgccagtg ttgctgcggc cattctcatg tacgaagttt tccgaaatag actataaaaa
    10861 agtttccagt catctgattg gaaacttttt tatgattaac tatgttctgt aatgaattta
    10921 taggcttctt gaccagcgat agctccatct ccaactgctg ttgttacttg gcgaaggtct
    10981 ttcaagcgaa catctccaac tgcaaagata ccgtcgactg cagtcttcat gtggctatct
    11041 gtcacaatcc agcctgcctg atcttggata ttcaattctt taacaaaatc gctaagaggg
    11101 tccaaaccaa catagataaa gacaccaccg aaggcttgct ctgtcacttg acctgttttc
    11161 acattttcaa aaacgacaga ttctactctg ttttcaccct tgattttcct tactacagaa
    11221 tcccatataa agctgatttt ctcattggca aaggcgcgat cttgtaaaac cttttgggca
    11281 cgaagttggt cacgacggtg aacaatggta acagtcttag caaaacgagt caagaagagg
    11341 gcttcttcaa cagctgaatc tccaccacca actaccaata aatcttggtc acggaagaaa
    11401 gcaccatcac acacagcaca gtaagaaaca ccacgactgt tcagttcttc ttctccaggc
    11461 actcccaaag gacggtgttt agaaccagtt gctacgataa ctgtacgtgt ttcatatgtt
    11521 tggtcatcag tcatcacttt cttaaaatca ccatggtctt cgacattttc aacataacca
    11581 taaatgtgct caacaccaag attttcaagt ggttcaaaca tcttttcagc caattcaggt
    11641 ccactaatat tagcgtatcc tgggtaattt tcgatatcag atgtattatt catctgacca
    11701 cctggcagac caccttcaat caaagctact tttagattgc ttcgagcagc atacaaggcc
    11761 gcagtcatcc ctgcaggtcc agcaccgata ataatagtat cgtacatata gattccttct
    11821 ttcttgttgt aactatcttt attctaactc tttcttgtca atcacgcaag gattatgcct
    11881 tgaaaacaag aattaaactc ataaccgcaa aggataatac tgggacaacc aagactccaa
    11941 tcataatcat atcatagaga tgggcttggc gagccttggc tgtcttatca actcccgaca
    12001 tggctctcag accaatccaa atccctaaaa aaatcagaac aaggatggtg gtcaagatca
    12061 aactctcgaa atataaagaa aatagttgca gtagcatgat ttctctcatt tctatctttt
    12121 ttaaagagta aactcagcta gtccaactaa ctgagttttc ctttatctat tatatcaaat
    12181 ataagtccgt ttgtaactag cgaagaattc ttttgtccgc tcttctttag gggtgtggat
    12241 aatctcatcc ggagttccag actcgatgat tttcccctta tctaagaaga gaatcttatc
    12301 cgcaacttgg gctacaaagg acatgtcatg actgaccaaa atcatggtct gacctgactt
    12361 agcagcatct gcaatagact tttctacttc accgaccaat tctgggtcaa gggctgaagt
    12421 tggttcgtct aagagcaaaa catctggttt catagcaagc gcacgcgcta gggcaacccg
    12481 ttgcttctgt ccacctgata aatggcgagg ataatggttt tcacggtccg aaagcccaac
    12541 cttagccaac tcttccttgg caatcttagt cgcttcttgg tcagataatt tcttgacaac
    12601 aaccaagcct tctttcacat tatcaagtgc tgttcggcgt tcaaacaaat taaactgttg
    12661 gaaaaccata gacaacttac ggcgtagggc aaggatttct tcttgagtga ttttagaaaa
    12721 atcaactgaa aaaccatcaa tctgaataga gccactgtca ggtgtttcaa gataattgag
    12781 actgcgaaga aaggttgatt ttccagctcc tgaagaacca atcaaggcta caacttcccc
    12841 tttttgaata tccaagtcca gatgatccaa gacagtctgt cctgaaaagg atttgcttaa
    12901 attcgaaatc ttaatcatta acgaaggtct cctttcacat ctgtttgcac tgtatcaggt
    12961 gcagaaatag ccatttttct ctcgatgaaa cgaccgagac tttcaattcc gatattgact
    13021 acccaataaa caagggcaac ggagatgaag cgttcaaaat agcgataatc agctccacct
    13081 agaatctgag cttgggcaaa gacttccaca acacccgcac taaaagctag agatgttccc
    13141 ttggtcaaac cgatgaggga attaatcaag gttggagtag ctaccaccgc tgcattagga
    13201 ataatcactc gtcgataaac ttgcgctcgg gtcataccca gactgcgtgc cgcctcaatc
    13261 tcaccaggat taactgagag aatggctgca cgaatggttt cactagcata agctgcctca
    13321 ttaaaggcaa aggcgacaat cgcaaaagct gcagctggaa tcgcattgat attgagacca
    13381 gttccccatt gctgattgag ggctttcaaa gccaaaggga ttccgtagta ggtcaacatg
    13441 agttgcacca aaatcggtgt cccttttaag aaactaacaa agaaggcctg caagggatat
    13501 aaaatcttga cacgattgat cttcacaatg gcaaaaagaa gcgccaaaac caagccaaaa
    13561 agggcaccac caattgtcaa cataattgtt gttggaagtt gttggacaat tctagggatt
    13621 ccatcaaaga ccgaacgtag gctaaacagc ttgccattcg gaatcaattg catcaagttt
    13681 tggtaccaat ctgatgctaa aatcgttgta acattcataa aaacatcctc ttctgataat
    13741 gattcattct accatgcttc tgccgtcaat gaaattattt gctacggtca gatacagact
    13801 ttgtctacct actagtttat catactttga aacagggaag ttatatattt tatctatcaa
    13861 agagatagat aaaaactatt tcagtcccag ttcttcataa gattttcgat aaccgatttg
    13921 cttaacggtt ccattttcta ctaaaatggg ccgttttaac aacataccgt cacttgctag
    13981 caactcagcc gcttcttggt ttgacaaact tcctacctta tcttttagcc ctaattcacg
    14041 gtatttgata ccactggtgt tgaaaaattg cttcaattca aatcctgagg tttctagcca
    14101 attcaaaatg acttcttggc taggtgtttc ttccacgata tggacggctt tatagtccac
    14161 acctaattga tttaattctt gttttgcttt tttacaagtt gaacatttgg ggtattcgat
    14221 aaattctaac atgtgcttct ccttctattg cttctatctt taaaatctac tccttcatgc
    14281 tccaagagcc aagctttctt ttccactcct gcagcataac ctgtcagacg cttgcctgct
    14341 cccaacacac gatgacaagg tactaggata gaccaaggat tgcgtcccac tgctccacca
    14401 attgcttgag cagaagccac ttgcaggtct tgagcaattt gtccataggt cactgtctga
    14461 ccataaggaa tgccctgtaa atagtcccaa actctctttt caaaattcgt tccgattggc
    14521 gccaagagca agttggataa atcctgaggc ttgcctttaa agtaatcatc taagcaagca
    14581 ataactgggt ctaaaatagg atgactaaca acttcttcta tcgtttcatc tcctagtccc
    14641 ctctcaaaat gcttctgctc ctgaacccaa attccataca aataatggtc atcagctaca
    14701 agtgatagaa taccaattgg tgaggagtag agtattttta catacttctt ttgcattatt
    14761 tctttaattt ttgataggcc aagcgttcgc catctactgg caccttacca acttgtttaa
    14821 aaccaagttt ttcaaaaata tgttgcataa ccttgttttc agcatgcgta tctgagcgaa
    14881 aatcaagata atcaaaacct tcaatcaagc cctctaagaa ggtttgagca actccttttc
    14941 cctgcacatc tgctgccaca gcaatacggt gaaagactag atactctgac tctccagctt
    15001 gccagtttcc ctcataaata gcttcatagg cctcctctgg actcttggtc acagcagcat
    15061 aggctagcag ttctccctct tccaaggcta cgtaggcttg ccctgagatg atatcatcga
    15121 taataacatc tgcatttgga tagccatttt gccactggtc actaccagca tctgctaaac
    15181 attttttggc atcctccatc acctgcatga tggcatctac ttcatttgga aaagctaaac
    15241 gaatttccat cttttttcct catttctgac tagtttctcc catcatagca taatttaagt
    15301 atttctacaa gcagttaaaa cttgactttg tgtttttgtt attttataat ctagttatca
    15361 aaactatata aaaaggagtt gaaaatgaaa actacctttt cctacccaaa atgggcagaa
    15421 attccaaaca ttgacctcta tctggaccag gttttgctct atgtcaatca ggtctgcgcc
    15481 cctatctctc ctaataaaga caagggccta acagcatcta tggtcaacaa ttatgtgaaa
    15541 aatggttacc tgacaaagcc tgacaaaaaa aaataccaac gccaacagat tgcccgtttg
    15601 attgctatca caaccctcaa gtctgtattt tctattcaag aaatagccca gacacttaat
    15661 actctacaaa ctcaagcaag ttcagaccaa ctctacgatg cttttgtgga ctacatgaac
    15721 caaggaattg acccagctaa ccctattatc caaaccagct gccaaaccgt taaactctat
    15781 catcaaactc tagacttaat cgatcatact caagaggagg taatccaatg aacactagtc
    15841 ttaaactcag caaacaactc agttttggag aggagattgc taatagcgtg acccatgctg
    15901 tgggtgcagt catcatgctt atcttgctgc ctatttcatc catctatagt tatgaagcac
    15961 acggattttt atcctctatc ggcgtttcca ttttcgtcat cagtctcttt ctcatgttcc
    16021 tatcatccac catttatcac tctatggcct atggttcgac ccacaaatat gttttgcgaa
    16081 tcattgacca ttctatgatt tacgttgcca ttgccggctc atacacgccc gttgtcttga
    16141 ccttgatgaa taactggttt ggctatctga ttattgtcat ccaatgggga acgaccatct
    16201 ttggtattct ctataaaatc tttgctaaaa aggtcaatga gaaatttagc cttgctcttt
    16261 acctgattat gggctggttg gttctggcta tcattcctgc cattatcagt caaacgacac
    16321 ccgttttctg gagtctcatg gtaactggcg gactctgtta tacagttgga gctggatttt
    16381 atgccaagaa aaaaccttat ttccacatga tttggcatct ctttatccta actgcgtccg
    16441 tacttcaata catcgctatt gtttattaca tgtaaaactc tcagtaggca gagcctgctt
    16501 agagttttac aaacgaattt cccaaagagg aagcaatatg aaagcagtca ttgcttgtgt
    16561 tcataaaatt ctcagaatca tttacaaact actctccacc aagtagactt atcaaaaaga
    16621 aaaggcgcta ggactgaaga aacagttcta acgcccaaat taaaaaaatt tcaactacag
    16681 tatagcacag gaaatgattt tttgcgcttt tttactgttt tttcaaataa aaaaagacaa
    16741 agttttatcc ttgtctttta gttttagtat tgctttggtt tcaatgtcaa taagtgtgtt
    16801 ctt
//
LOCUS       DAVKMJ010000043        14400 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000043 DAVKMJ010000000
VERSION     DAVKMJ010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14400
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.043"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            83..880
                     /locus_tag="VW348_001673"
     CDS             83..880
                     /locus_tag="VW348_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEU9746546.1"
                     /translation="MISSEFISKIEFACNKKESLYSQSKFKYAIRSIFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGSLIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1028..1150
                     /locus_tag="VW348_001674"
     CDS             1028..1150
                     /locus_tag="VW348_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HEU9746547.1"
                     /translation="MTRDFKFETLQLHAGQVVTPATESRAVPIYQTTSFVFDDT"
     gene            1172..2287
                     /locus_tag="VW348_001675"
     CDS             1172..2287
                     /locus_tag="VW348_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEU9746548.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDIDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFATPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGSSCHNLSYIRDVGAATFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETLSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKGVGSIFTFHVKGDEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPNQIRLSIGLENVEDLIEDLRLALEKI"
     gene            2383..3657
                     /locus_tag="VW348_001676"
     CDS             2383..3657
                     /locus_tag="VW348_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEU9746549.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="VW348_001677"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="VW348_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEU9746550.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTKTEDASGEVVAETPVLSLLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4786..5088
                     /locus_tag="VW348_001678"
     CDS             4786..5088
                     /locus_tag="VW348_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEU9746551.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5196..5834
                     /gene="udk"
                     /locus_tag="VW348_001679"
     CDS             5196..5834
                     /gene="udk"
                     /locus_tag="VW348_001679"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEU9746552.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5962..7302
                     /locus_tag="VW348_001680"
     CDS             5962..7302
                     /locus_tag="VW348_001680"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEU9746553.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7280..7492
                     /locus_tag="VW348_001681"
     CDS             7280..7492
                     /locus_tag="VW348_001681"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEU9746554.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7489..8364
                     /locus_tag="VW348_001682"
     CDS             7489..8364
                     /locus_tag="VW348_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEU9746555.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8357..9172
                     /locus_tag="VW348_001683"
     CDS             8357..9172
                     /locus_tag="VW348_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEU9746556.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDVKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9165..9596
                     /locus_tag="VW348_001684"
     CDS             9165..9596
                     /locus_tag="VW348_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEU9746557.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9603..11270
                     /gene="recN"
                     /locus_tag="VW348_001685"
     CDS             9603..11270
                     /gene="recN"
                     /locus_tag="VW348_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEU9746558.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGVPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLHLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVHFSKGKFSRGGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11272..12000
                     /locus_tag="VW348_001686"
     CDS             11272..12000
                     /locus_tag="VW348_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEU9746559.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12079..13902
                     /gene="lepA"
                     /locus_tag="VW348_001687"
     CDS             12079..13902
                     /gene="lepA"
                     /locus_tag="VW348_001687"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEU9746560.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPESVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14151..14231)
                     /locus_tag="VW348_001688"
                     /pseudo
     CDS             complement(14151..14231)
                     /locus_tag="VW348_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
BASE COUNT         4281 a         2615 c         3404 g         4100 t
ORIGIN      
        1 acttttatga aatacagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatgatttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 attcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggat ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg acacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ctcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat aatatggagg
     1021 tcaccttatg actcgtgatt ttaaatttga aactctacaa ctacatgctg gtcaagttgt
     1081 gactccagct actgagtctc gtgcagtgcc gatttatcaa acaacatctt ttgtttttga
     1141 tgacacgtag gaaggtgctg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatattga taatttggag gaagtagaag cagctatcaa
     1441 agacaatacc aagcttgtct tgattgaaac cttgggtaac tccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaaca ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggacggctt cagggaaatt ccctcaattt gttgacgagg gttcaagctg
     1741 ccacaatttg agctatattc gtgatgtggg tgcagcaacc tttattatag ctgttcgagt
     1801 tcaattgctt cgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa actctttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttatcat gccttggctg agaaatactt gccaaaaggt gtcggttcaa tctttacctt
     2041 ccacgtcaaa ggtgacgagg aagaagcacg caaggtcatt gataatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgctaaatc gcttgttgtc catccagcaa caaccactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaacc aaattcgtct
     2221 gtcaatcggt cttgaaaatg tagaagattt gattgaagac ttacgcttgg ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg ttttgactca ctgtttttga ttttccctca
     2341 ggcatgatat aatggttaca gaagtctaga aagaggaatg taatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gaaagccagt atgctgaact tttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaggcagga actggccttg
     2521 gctgagcaaa aggctatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattac agagtcagat ccaaaacttt gatacagaaa aagaattggc caagaaagag
     2641 gttgaacaga caagccatga ggctctcttg gctaaggaca aggaagtaca gctcttagaa
     2701 aatcagttgg ctaccttgcg tttggagcat gaaaatcaac tacaaaagac cctttctgac
     2761 ctagaaaaag aacgggatca ggttaaaaac caactacttt tgcaggaaaa ggaaaatgaa
     2821 ttatctttgg cttctgttaa gcaaaactac gaagcccagc tcaaggcagc tagtgaacaa
     2881 gtcgagtttt ataagaattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa cgaagcggac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggctgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc aattgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagatttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgacc
     3541 acatctgaaa accaactccg tttagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat taacttaaaa aaggaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggtcgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaatcactc tgggctattc cacgaagact
     3901 gaggatgcta gtggggaagt ggtcgcagaa acccctgttt tgtctctctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta ctcagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gaccatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgcccgatt cacttttcgt gtaaaatgca gtaaagggac gtacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctcttg ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcttgat aaaaccccat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct atatagaaat
     4681 ttagaggtgt gaaatgaagc aatttaaaat tctttcagat aaatatttag agtccattac
     4741 aggttctgat gggaacttag gcccaggatt tggtgtgata attccatgat gcgaaatgag
     4801 tttcgagaaa gggtggagca acttcttcaa caaaaagaaa taaatgaaaa tagtgagttg
     4861 agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa atgaaaaata ccaatcggtc
     4921 atggccaatt tgagtcaagg gttgtcactt tacctcatga cgcatcatta ccaggcacct
     4981 aagtctgtca ttgattttgg tttatggatt gccaaagctc ctagccagga aagagggaga
     5041 ctggctttct tgcagatgct tgctcaaacc ctacagggct ttcgttaaaa ctgtcgaaca
     5101 tcagagggaa gactctggtg ttttttgctg atgagactat aaattttgta aaaaatgtga
     5161 tagaatagac gacggataaa ataacggagg atagcatgca aaatagacca atcattattg
     5221 gagtgacagg tggttctggt ggtggtaaaa ccagtgtttc aagagccatt ttatcgcatt
     5281 ttcctgatga aaagatttcc atgattgagc atgattcata ctacaaggat cagtctcatt
     5341 tgacctttga agagcgtgtc aaaaccaact atgaccatcc ttttgccttt gatacagact
     5401 tgatgatcga gcagattaag gaattgttgg cagggcgtcc ggtggacatc ccgacctacg
     5461 actatacaga gcatacacgg agtagcaaga cctatcgtca ggaacctcaa gatgtcttta
     5521 tcgttgaggg tattttggtc ttggaggaca agcgtctgcg cgatttgatg gatatcaaga
     5581 tttttgtgga tacggatgac gatgtgcgca ttattcgtcg tatcaagcgt gatatggagg
     5641 agcgtggccg tagccttgat agcgttatta accagtactt aggtgtggtc aaaccaatgt
     5701 accaccagtt tatcgagtca actaagcgtt atgctgatat cgtcattcct gaaggggtta
     5761 gcaataccgt ggctatcgac ctgttgacga ccaagattgc aaagattttg gaagaagctc
     5821 gaaacagcaa ataatcacat gtggaggcct tgcctccttt ttctattttt ccctcataat
     5881 ggtacataaa tggagatttt taggcatatt tttggtataa taatacccat gaaagagcaa
     5941 gtaaatgaat agtaggtgga gatggaaaag tatttatcgg taacaacttt gaccaagtat
     6001 ctgaaaatga aattcgataa agacccatac ttggaacggg tctatttaac tggtcaagtt
     6061 tccaactttc gtaaacgacc tactcaccaa tatttctccc taaaggatga ccatgcagtt
     6121 attcaagcga ccatctggtc tgggatttat cagaaattag ggtttgacct ggaagaagga
     6181 atgaagatca atgtgattgg gcgtgtacag gtctatgaac caagtggtag ctactccatc
     6241 atcattgaaa aagctgagcc tgatggggtt ggggcgcttg cgattcagtt tgaacaactt
     6301 aagaaaaaat tgacagaaga aggcctgttt caagaacgct tcaagcaagc tctgccccaa
     6361 ttttctaaga gaattggtgt agtaaccagc cgtagtggag ccgttattcg agatattatc
     6421 acgaccgtca gcaggcgatt cccaggtgtt gacatccttc tttatccgac caaggttcaa
     6481 ggtgaagggg ctgcggagga aattgctaga aatattgcgc gtgctaatca acgggacgat
     6541 ttggatttgc tcattattgg tcgtggaggt ggttctattg aggatctctg ggcctttaac
     6601 gaagaaattg tggtacgagc tatttttgaa tctcgtttgc cagttatctc tagtgtgggg
     6661 catgagacgg atgtgacctt ggcagatttt gtggcagatc gacgcgctgc aacgccaaca
     6721 gcggcggctg aactggcaac acctgtgacc aagttggatg tattagctca tttgcaaaat
     6781 caggaaaaac ggatggtaac ggcagtccga aatgttctat ctaagaaaca agaggctttg
     6841 aaaaaatgca gtcagtctgt tatctttaga caacctgagc gcttgtatga cggttatttg
     6901 caacgcttgg accaactgca actgcgtttg aaacaaagtt tgcgaactcg gatttctgat
     6961 aacaaacaat tagttcaagc aagaactcat caattagtac aattatcacc tgttaccaaa
     7021 atccaacgct atcaagaccg tttaggacag ttggacaagc tcttaggtag ccaaatggcg
     7081 ttagtttatg acgccaaggt tgctgaggcc aagcgacttt cggaagcttt gctcatgttg
     7141 gatactagcc gaatcgtggc gcgtggttat gctattgtca aaaaagaaga gtccgttgta
     7201 gattcggttg agagtttgaa gaaaaaagac caagtaacgc ttttgatgcg agatggtcaa
     7261 gtagaattag aggttaaaga tgtcaaaaca aaagaaattt gaggaaaatc tagcagaact
     7321 ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct ctggaagatg cgattactgc
     7381 ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct acgctggaca aggctgaaaa
     7441 gaccttggtc aaggtcatgc aagaagacgg aacagaaagt gattttgaat gaaaaagcaa
     7501 gaaaaattag ctcttgtcga gtcggctttg gaagattttt atggagacca gcagtttgcc
     7561 tctagtttac gggagtctgt tctctattct attcatgctg gtggcaagcg tattcggcct
     7621 tttctcttgt tagaagttct ggaagccttg caggttacca tcaaacctgc tcacgcgcag
     7681 gtagctactg ccttagagat gattcataca gggagcttga ttcacgatga tcttcctgct
     7741 atggatgatg acgattatcg aagagggcgg ttaaccaatc acaagaaatt cggtgaagct
     7801 atggccattt tggctggaga tgctttattc ttagacccat atgccttgat tgcgcaggca
     7861 gatttgccaa gtcagatcaa ggtggacttg attgccaact tatcccttgc ttcaggtagt
     7921 ctgggtatgg tggcagggca agttttggat atggagggcg aacaccagca cttgtctctg
     7981 gaagaacttc agactattca tgccaataag actgggaagt tactagccta tcccttccaa
     8041 gcggcagcta ttatagctga attgtcacct gaaatgcagg tgaagctgaa aactgtgggt
     8101 gaattgattg gacttgcttt tcaagtcaga gatgatgtac tggatgtgac agctagtttt
     8161 gaggaaatcg gcaagacacc tcaaaaggat ctgcaggcag aaaaatcaac ctatcctgcc
     8221 ttgttgggct tggaagagtc cattgccttt tgtaaccaaa ccctggatca agctaatgaa
     8281 aaattagaag aaattgccca gcagcttccc tttgaaacag aatcgattgt aagtgtagta
     8341 gaaagtttga gaatcaatgg ctaaggaaag agtggatgta ctagcttata aacaggggtt
     8401 gtttgaaacg agagagcagg ccaagcgagg tgtgatggct ggcctagtcg tagcagtcct
     8461 taatggagaa cggtttgaca agccaggaga gaaaattcca gatgacaccg aattaaaact
     8521 caagggggag aaactcaagt atgtcagccg tggtggtttg aaactggaaa aggccttgca
     8581 ggtctttgat ttgtcggtgg atggcgcgac tacgattgat atcggggcct ctactggagg
     8641 ttttaccgat gtcatgctac agaatagtgc caagttggtc tttgcagtcg atgttgggac
     8701 caatcagttg gcttggaaat tacgccaaga cccacgagtt gtcagcatgg agcagttcaa
     8761 tttccgctat gctgaaaaga ctgatttcga gcaggagccg agctttgcca gtattgatgt
     8821 gagtttcatt tcccttagtc tgattttgcc agccttgcac cgtgtcttgg ctgatcaagg
     8881 tcaggtggta gcacttgtca aacctcagtt tgaggcagga cgtgagcaga ttgggaaaaa
     8941 tggaattatt cgagatgtta agattcatca gaatgtcctt gaatctgtaa cagctatggc
     9001 agtagaggca ggtttttcag tccttggctt ggacttttct cccatccaag gtggacatgg
     9061 aaatattgaa tttttagcgt atttgaaaaa agaaaagtca gcaagcaatc agattcttgc
     9121 tgagattaaa gaagcagtag agagggcgca tagtcaattt aaaaatgaat aaaaaagaaa
     9181 gacttgaaaa aattagaaga ttggtgacag attatcaaat cggcacgcaa gaagaaattg
     9241 tagaacattt gaaagaagca ggtatcactg ccactcaggc gacggtatcc cgagatatca
     9301 aagagttagg tattgtcaaa attcctttga gagacaacac ctatgtctac gaattaccaa
     9361 aatcaatcgt aaaaagtctg caactggctg aagacaatat cgaatcggct gaattgatgg
     9421 ataagatgat caatctccaa gttattccag gaaatacggc ttttgtaaaa gctcagttaa
     9481 tcgagacttt tgcagacaag atttttagct gtttgactga tgatagctcg attttagtca
     9541 ttgccagaag tggaagtcta gcagaggaaa tctttgaaca agtaaaaaat tggtaggtct
     9601 atatgttact tgaaatttcg ataaaaaact ttgccattat tgaggctatt tccctcaatt
     9661 ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc agggaagtcg attatcattg
     9721 atgccatgaa tatgatgttg ggagctcgtg cgacgacaga tgttattcgt catggtgtac
     9781 caaaggcaga gattgagggg cttttctcag ttgagaatag tcgtctttta caggaaattt
     9841 ttgatgagca aggtttagaa ttaggtgatg aaattatcat ccgtcgggaa atcttgcaaa
     9901 atggtcgtag tatcagccgt gtaaatggtc agatggttaa tctgtctgtt ttgcgagcta
     9961 ttgggcaaca tcttgtagat attcatggtc agcatgacca tgaggagtta atgcgtcccc
    10021 aactgcatat ccagatgttg gatgaatttg gtgatgccgc tttttgggac ttgaaagaaa
    10081 cctatcaaac gagttttgat gcctatcgga aaatgcgcaa gcaggttctg gaagtcaaga
    10141 aaaaccaaca ggaacacaag gcacgtatcg aaatgttgga atttcaaatg gcagagattg
    10201 aggcagcaaa cttgcaggct ggagaagact tggctctcaa tcaagagcga gataaactcc
    10261 tcaaccacaa aaatattgcg gatacactga ccaatgccta cagtatgttg gacaatgaag
    10321 atttttcaag tctggccaat gttcgttcag ccatgaatga catggaaagt gtcgaagagt
    10381 atgaccctga ataccgtgaa atttcaagct ctctgtctga gacctactat gttttagaag
    10441 acattagcaa acgtttggaa gctatcattg aggaccttga ttttgatggc aatcgcctca
    10501 tgcaggttga gaatcgtttg cacctccttc atactattac tcgtaagtat ggtgggactg
    10561 ttgatgatgt tttgctttat tttgccaaga ttacggaaga atacaatctc ttgacaggca
    10621 ataatctttc gtctgaggac atggaagcag agcttaagaa gttggaagtc aatcttgtca
    10681 atttggcagg tcaacttgct tctgctcgtc ataatttggc tcagcaactc gaagctgaga
    10741 ttaaacaaga actgcaagat ctttatatgg aaaaagccca gtttcaggtt cattttagta
    10801 agggaaaatt cagtcgtggg ggaaatgaaa tggttgagtt ttatatttca accaaccctg
    10861 gagaagactt taaacccttg gttaaggttg cttctggagg ggaattatct cgtctcatgt
    10921 tagccattaa gtctgccttt tcacgtaaag aaggcaagac tagcattgtc tttgatgagg
    10981 tggatacggg agtttcaggt cgtgttgctc aagctattgc tcagaaaatt cataaaattg
    11041 gtcagcatgg tcaggttttg gctatctccc atttgccaca agtaattgcg attgcagatt
    11101 atcaattctt tattgagaag attagtaatg accattcaac ggtttcgact gttcgtctct
    11161 tgacagtcga agagcgagtg gaggaagttg ccaagatgtt ggcaggtgat gatgtgacag
    11221 aagcagccct gacgcaagcc agagaattgt tgagaaacag ggagaaataa gatgacagat
    11281 tattatgtaa ttggagatgt tcacggaaaa gctgggatgc tggaagacct tcttaaaacc
    11341 tgggatggtc agacccagtt gctctttcta ggtgatttga ttgacagagg tgaggatagt
    11401 caccgtgttc ttgaaatggt caaggacttg gtggacaatc aaggggctat ctgtttgtct
    11461 ggaaaccacg agtatatgtt tttgacttgg ctagatgacc cagaagaaag ttatgaccat
    11521 tatcgtcgca atggtggaga tacaaccatt aactctatcc taggtcgtcc cttggatgca
    11581 ccagttgatg gagtagaaga tgccaagcgg gttgccgctg aagcgtcaga cttggtcgaa
    11641 ttcattcgtc aaatgccatt tgtagtagag acagacaagt atatatttgt tcacgcaggt
    11701 attgatttga ctttggacga ctggcatgaa acaacagatt ataaaaaagt atggcttaga
    11761 aaaccattcc acggagctga aaatcatact ggaaaaacca ttgtcttcgg tcatacaccg
    11821 gtctatggtt tgttacagca agaacgcggt acatctgagc tttggactac agaagatggc
    11881 aagattggaa tggatggagg agctgtttat ggtggtgtcc ttcacgggat tgtctttaca
    11941 gaccaaggaa tgacagaaca ccactttatc gaaaatgacg gctttgtcgc tgaagattag
    12001 tactcctagc agggtatggt cttgtcaaaa tatcaaaaac aatttataat aaatagatac
    12061 cctgaaagga agagaatcat gaacttagaa gaattgaaaa aacgacaggg gaagatccgt
    12121 aacttctcta ttatcgccca tattgaccac gggaaatcaa ctctagcaga ccgcattttg
    12181 gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc agcttttgga tagcatggat
    12241 ctagagcggg aacgtggaat tactattaag ttgaatgcca tcgagttgaa ttacactgca
    12301 aaagatgggg aaacttatat tttccacttg attgacacac cagggcacgt tgactttacc
    12361 tatgaagttt cacgttcgct agctgcctgt gagggtgcta ttttggtggt cgatgcggct
    12421 caaggaattg aggctcaaac tcttgccaac gtttatctgg ctttggataa tgatttggaa
    12481 atcatgccta tcattaataa aattgacctg ccggctgcag atccggagag cgtgcgtaca
    12541 gagattgaag atgtgattgg tttggatgcc agtgaagcag ttttggcttc tgccaaggct
    12601 ggtattggga ttgaagaaat cctcgagcaa attgtagaaa aagtaccagc accaacgggt
    12661 gatgtgacgg cgccacttaa ggccttgatt ttcgactctg tttacgatgc ttaccgtggg
    12721 gttatcctcc aagtgcgtgt catggacgga gtggtcaaac ctggtgataa gattcagctc
    12781 atgagcaata gtaagacctt tgatgtggcc gaagtcggta tttttacacc aaaagcggtt
    12841 ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg cggcgtctat caagacggtt
    12901 caggatactc gtgtgggtga taccgttacc ttggcaacca atcctgcggc agaaccatta
    12961 catggttata agcagatgaa tcctatggtc tttgcgggtc tctacccaat cgaatcaaac
    13021 aagtacaatg acctgcgtga agcgcttgaa aaattgcaac tgaatgatgc tagtcttcag
    13081 tttgaaccag aaacatctca ggcacttgga tttggtttcc gttgtggatt tcttggactt
    13141 ctccatatgg atgttatcca ggaacgttta gagcgtgagt tcaatattga tctcatcatg
    13201 acagctccgt ctgttattta caaagttaat ttgaccgacg gtgagtctat ggatgtgtct
    13261 aacccatctg agtttccaga cccaactaag attgcgacca ttgaagagcc ttatgtcaag
    13321 gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa tggagctagc tcagcgtaag
    13381 cgtggggact ttgtgactat ggactatatt gatgataacc gtgtcaatgt tatctatcaa
    13441 attcctcttg ctgaaatcgt ctttgacttc tttgataaac ttaagtcttc gacacgtggt
    13501 tatgcaagtt ttgactacga attgtcagaa tatcgcccat ctaagctagt gaaaatggat
    13561 atccttctca acggagacaa ggtggatgcc ctcagcttta tcgttcataa ggactttgct
    13621 tatgaacgtg ggaaactcat cgttgataag ctcaagaaaa tcatccctcg ccaacaattt
    13681 gaggttccaa tccaagcggc tattggacac aagattgtcg ctcgtactga tatcaaggcc
    13741 cttcgtaaga acgtacttgc taaatgttat ggtggtgacg tttctcgtaa gcgtaaactc
    13801 cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca tcggatcagt tgaagttccg
    13861 caagaagcct tcctcagcgt cttgagtatg gatgaagaat aagttatcag aaatgccttt
    13921 ccttgttcac aggaaattta tataagaatc aatagtaaag caggcttaga tggtctgctt
    13981 ttttagtttt tatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat
    14041 gtatggttac tgacttcgtc agtttcatct acaatctcaa aaccatgttt tgagctgact
    14101 tcgtcagttt catctacaac ctcaaaacca tgttttgagc tgacttcgtc agtttcatct
    14161 acaacctcaa aactgtgttt tgagtaacct gcggctagct tcctagtttg ctctttgatt
    14221 ttcattgagt attagaacag aaaaatgctt ggagtatttg tttgtgtgtt tatttttata
    14281 taacaaacta taaacacaac aaaaatataa aaaaagagac aaaaaagaac agaaagtaat
    14341 taacaacgat ttcatatagt gttatactta tagcataaag ttaatggaaa gaagggaaaa
//
LOCUS       DAVKMJ010000044        13900 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000044 DAVKMJ010000000
VERSION     DAVKMJ010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13900
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.044"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..513
                     /locus_tag="VW348_001689"
     CDS             1..513
                     /locus_tag="VW348_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEU9746561.1"
                     /translation="MIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSDHEWM
                     LTDIKNFLTKHKAWVIDGNYSWCCYQERMQEADQIIFLNFSPLTCLFRTFKRYLKYRG
                     KVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRELDQF
                     LDKKRKSYNS"
     gene            complement(536..1246)
                     /gene="deoD"
                     /locus_tag="VW348_001690"
     CDS             complement(536..1246)
                     /gene="deoD"
                     /locus_tag="VW348_001690"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU9746562.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(1904..2416)
                     /locus_tag="VW348_001691"
     CDS             complement(1904..2416)
                     /locus_tag="VW348_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEU9746563.1"
                     /translation="MSAQITINHKKARYVRIGLEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            complement(2441..3421)
                     /locus_tag="VW348_001692"
                     /pseudo
     CDS             complement(2441..3421)
                     /locus_tag="VW348_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            complement(3897..4706)
                     /locus_tag="VW348_001693"
     CDS             complement(3897..4706)
                     /locus_tag="VW348_001693"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEU9746564.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            complement(4706..5263)
                     /locus_tag="VW348_001694"
                     /pseudo
     CDS             complement(4706..5263)
                     /locus_tag="VW348_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199123.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            complement(5265..6476)
                     /locus_tag="VW348_001695"
     CDS             complement(5265..6476)
                     /locus_tag="VW348_001695"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEU9746565.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAEINPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            complement(6490..7173)
                     /gene="rpiA"
                     /locus_tag="VW348_001696"
     CDS             complement(6490..7173)
                     /gene="rpiA"
                     /locus_tag="VW348_001696"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEU9746566.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            complement(7455..8327)
                     /locus_tag="VW348_001697"
     CDS             complement(7455..8327)
                     /locus_tag="VW348_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEU9746567.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            complement(8469..9326)
                     /locus_tag="VW348_001698"
     CDS             complement(8469..9326)
                     /locus_tag="VW348_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEU9746568.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASYITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            complement(9480..10214)
                     /locus_tag="VW348_001699"
     CDS             complement(9480..10214)
                     /locus_tag="VW348_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9746569.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESRKVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            complement(10214..10897)
                     /locus_tag="VW348_001700"
     CDS             complement(10214..10897)
                     /locus_tag="VW348_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEU9746570.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            11087..11317
                     /locus_tag="VW348_001701"
     CDS             11087..11317
                     /locus_tag="VW348_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEU9746571.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            11546..13804
                     /locus_tag="VW348_001702"
     CDS             11546..13804
                     /locus_tag="VW348_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEU9746572.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKTEVKSSEKEK"
BASE COUNT         4123 a         3137 c         2541 g         4099 t
ORIGIN      
        1 attatcggat attctggttc tggtaagtca actctagcag aaaagttatc taactactac
       61 tccattccaa aactgcacat ggacacactc caatttcaac ctggttggca agacagtgac
      121 cacgaatgga tgttaaccga tataaaaaac tttctcacca agcataaagc ttgggtcatc
      181 gatggtaatt attcttggtg ctgctaccaa gaacgaatgc aagaagctga ccaaatcatc
      241 tttctcaatt tttcgccatt gacctgtctc tttagaacct ttaagcgtta tcttaaatac
      301 cgtggaaaag tcagagaaag tatggcggca gattgccctg aacgctttga ctgggagttt
      361 atcagatgga ttctttggga tgggcgtagc aaaactcaaa aagaaaatta ccaaaaactt
      421 tgccaagaat attcacataa agtcactatt cttcgaaatc agagagagct agatcaattt
      481 ctggataaga aaaggaagtc ctacaattca taaagggctt cctttttggc tataattatt
      541 ctgcaatcaa ggtttccaaa ccaaccttca tcatatcagt gaaggtattt tgacgttctt
      601 ctgcagttgt gtcttcgtct ggattgacca agctatcaga gatggtcatg atagctagcg
      661 catcaacatg gtattgggca gcaagatagt aaagagctgc tgcttccatt tccacagcct
      721 tgactcccca tttaccaagc tcgatattct tttcaaagta atttgagtaa aagacatcag
      781 atgacaaaac gttcccaacg tgagtagtca taccaagttt tttggcgata tggtaggctt
      841 tatcaagcaa atcaaagcta gcaatttgtg gaaaatcgta ctgtggccag tcattacgaa
      901 cgatgtttga gttggttgca gccgcctgcg ccaaaactaa ttcacgaaca tgaacctctt
      961 cattcaaaga acctgcagtt cccacacgaa tcaatttctt cacaccgtag tctacgatta
     1021 actcacgcgc ataaatcgaa atagatggca ttcccatccc agttcccatg acagatacac
     1081 agtgaccctt gtaagtacca gtgtaaccaa acatgttacg cacttcgtta aaacaaacag
     1141 catcatcaag gaaattctcc gcaataaact tagcacgaag aggatcccca ggaagaagaa
     1201 ttttatcagc aatttcaccc tgctgagcag caatatggat agacataatt tatgatacaa
     1261 agagcgagaa gaaaacgact gaaaattagg aacctgacga gaaatcctga tttttcagtc
     1321 agattatcta ttttccgagt tttccgctcg tgttcaaatc aaaacacacg ctctaccttt
     1381 ctttatttta tattttatat tgagaaagat accaaaccca tcaaaaagcg aagggaaaat
     1441 aggagttggg cgcagtgagc gatgctcgct agaccaacta tctttttccc actgctttta
     1501 gggtggggtc aattcctttc tttcttaatt ttgatttaga ggagagtcgc ccgtattcag
     1561 ttcagcgaat acagtttacc catcctttcg tttttatttt tagaaaagtt ttctactcgt
     1621 gttcaaatta gaacacgcgc tctacctttc tgtttatact cttcgaaaat ctcttcaaac
     1681 cacgtcaacg tcgccttgga ttatatatgt gactgacttc gtcagtctta tctacaacct
     1741 caaagcagtg ctttgagcaa cctgcggcta gtttcttagt ttgctctttg attttcattg
     1801 agtattaatt ttgttctttc acagagagct acctgagttc tattcaagct caggtagtac
     1861 tttcttataa actagacaaa ctaactgtca ttgtaccatc agattacaag acatcatcgt
     1921 cactcacctt ggaattcaat gtcgtacccc aatgggtaat tttacggtgg ggttgagcta
     1981 aaattggtct gttttcatag attgtttgcc atctattcca tagtaggccc gtctttttct
     2041 caatcttaac tcgcagattt ctcatatttt ctttgattgg gaggttgagg acaaaacctg
     2101 cagtctggtt gcgaccgttt ccttcccaag aatgactacg aacaacttgg tttccatctt
     2161 tatctactgt aacttcttcc caagttatgg agtagcgggc aatgtaagct ccactgtgtt
     2221 gaattgtcaa tgttttatct ttcacaggag tctgactgat tggttgaact ggcttagaaa
     2281 cttgtgtcgc cgtttcagca ttcgtagcta taaagcggaa aacttcaact tctgcaagac
     2341 tgagggcatt atagccttct agcccaatcc gaacatagcg cgctttttta tggttaatcg
     2401 taatttgtgc tgacacatct ttaggagata ttatacgttt tcactcaatt tctttaccag
     2461 aactgtctaa aagaatgaca tcaaagtttg ccaatctatc ctgggcagtg tctgttcggt
     2521 tgtaaatatt gatttggcga atggtttctt ctttagccaa atctacttgc caccaaggct
     2581 tagattggaa gtttgtatga gtgacagaat tgtgaccata gttaccatcg actttgccat
     2641 ccacagctct tctagcatct cctccgaaag ctgtcgaact ttgagtaacc tgttttccta
     2701 aggcaatatt ttccattggt tcagcgcttg gttgactaga agattgaggt agagcctgtt
     2761 tcttaaagaa tcgcacttta tccaatttcg gatcacgata accatgttta tccaaggtag
     2821 cttgtttacc aatattaaag ttaggaatat cattcattgg actttcaaaa tagccacgag
     2881 aacggtgttt aaagcgtgaa ttacctgtaa atgtaacaat atcacgatta ttatgaatca
     2941 agggagtcac aacattgtca ttatcaacca cataatgctt aatttttcca ctaacagcta
     3001 atttacgact ttccaaacca acatctcaga aaccattctt agcatcccaa acagttctgg
     3061 aagtaatcac tttaggagca ctgaaagttg tcactttcct caatacatgg ttataaaaat
     3121 caggatattt ttggtaagct tcaaccgctg caatctgagc taggtaacat ccaagagaat
     3181 gacctgtcat atacaactta gtaatactta tatccttggc taattcccca acaaccttgc
     3241 ggatatcatc cgcttgagct ggctctatta tctctacttt tgactcttcc cttttgtttt
     3301 caagaacttc acttgcttcc ggaagcgttt gaggagctag tcttggctcc tctctaagag
     3361 gagtttctag ttttggagca tcattttctg actctttcaa ttcctcctta gaatctagca
     3421 cacctattac cacttcagat gttacatctt gctttacttc attggctgaa attccagctg
     3481 gagctagaaa tcaaagccga ctacaacaga tacaactccg atacttaatt ttttatgcca
     3541 aagcgcataa ttcgttgacc aattttcatt atttcttatc tttcttttcg tttatttaca
     3601 agcagactca agcgaaatct cattgtgcta tatatgataa gactgagaaa ttcagaaagt
     3661 caattcattc tcatctctcc ttatcatact agtctacttg gctaggaagc taatgctagt
     3721 atcctagaat cttgtctttc acaatgctgg ctatcagatc agacacacct attcttccgc
     3781 ttctttcagt tataagagca ggaagaagct catagtattc ctctgtttct tctttaatcc
     3841 ggataggcag tcaatcctga aaaaacagag gcactccccc ttttaaatct tttttcttac
     3901 aattcagcaa gaatcgcttt aagcaagcct ttgaaatcac ctttaacacg ttcagtcact
     3961 tctacaactt cttcgtgatt gagttcttct tggaaaccgg ccgcaaagtt agtgatacat
     4021 gaaattccca gaactttcaa gccagagtgg gccgccacga taacttcagg aaccgtagac
     4081 ataccaactg catctgctcc cagtgtctta taggaacgaa tttctgctgg tgtttcataa
     4141 gtcggaccag taactccgat atagacacct tcatcaagct tgatattaag ttttttagcc
     4201 acttcatggg cagtggcacg gtattctggt gtgtaggccc tagacatatc tgggaaacgt
     4261 gggccaaagt catccaagtt ttcacccatc aatggatttt gccccgtcat gttgatatgg
     4321 tctgagatag ccatcaaggt accaggacca aatccgatac cgccagctgc attggttaca
     4381 ataacacctt cacatccaag aactttcatc acacgaactg ggaaagtcac cacttccaga
     4441 ggattccctt catagaaatg gaaacgccct tgaagagcca agaccttgcg acctgccagt
     4501 tcaccatata ccaatttacc agcatgaccg actactgttg aacggcccca gtttggaatc
     4561 tcagcatagt ctactacaac tggattttcg atttcttctg ccaattctcc aagtcctgac
     4621 ccaaggatta gaccgaactc aggggctgca attccctttt ctttcaggaa agtagcagtt
     4681 tcatggattt tgtttaaaaa tgtcattatg tgtctccttt attatttttt agcatttgac
     4741 caattttgtc aaaggtttta gcattacgaa tagtaatgtg gcggtagaaa ggcaccttca
     4801 gcaagtactt atgataggca gtcttagaat aggattcttc agaaaatttc ccccagaaaa
     4861 tcccaagttt tctaaaataa agcacttcat ctttcagctc taaactttca actgtcgcga
     4921 tgacttggtc cacatccaaa ccctcagtgt aaaagagaaa atcttttcgt gccaagtctc
     4981 tgctccacca agctggtaga ttttcaagtt ccgcctcaaa gtcctctaga ctcagtaaag
     5041 aaaagctctg aataaatgga taatggactg caaagaaagt ctctagcttt taaaccaatt
     5101 gggctttgga atctatcgaa gtaaagaaaa tattgccact gttgatgtag ctctcaacct
     5161 tttccagtcc caagtttgtc aattcttgac gaagctccgc cataacgacc ttattcttac
     5221 taccaacatt gatacctctc accagcaaag catagcgcgt catcttatac caatttatct
     5281 aagaaacttt ccccaatcat agcagtttcc acaccaaagt tatcggcaac agtcgctgaa
     5341 atatctgcaa aatgtcctac tggaatgaga ccatttcctt taaaggcagg gctatatgcc
     5401 aacaatggaa tatattcccg agtgtgatcc gtccctgcat acgttgggtc atttccatgg
     5461 tccgcagtaa tcaagagaag gtcattctct ctcatagctg cgataatttc aggtaagcgt
     5521 tcatcaaact catgcaaaca atcacggtaa ccgtgagcat tacgacgatg gccgtaaagg
     5581 gcatcaaagt caactaggtt tgtgaatgag aatccttttt caaactcagc aagtcccata
     5641 gtcttcaata gtgtatcaat tccatgacta tttgacttgt tgtgacccat gtcatggttg
     5701 ataccagcac cgttaaagat atcgttgatt ttacccacag cataagtatc gataccagcc
     5761 tcattcaatt tatccaaaac agttggggaa aatggagata cagccaagtc acgacggttt
     5821 gccgtacgag tgaagttacc tggttcacct acataagggc gagcaatgat gcgaccaaga
     5881 agggcaggac gctcaagggt aatcgaacga gcgtattcac agatacggta caattcatcc
     5941 aaaggaataa tgtcttcgtg ggcagcaatc tgcaaaacag ggtcagctga agtatagata
     6001 atcaactctc cagtttccat ctgacgtggt ccaaaatcat cgataacagc cgttcctgaa
     6061 taaggtttgt tggcttcacg aataaccttg cgtcctgaga attcttcgat ttttgtcagg
     6121 atttcttctg ggaatccgtt ccagaaagta tcgaaaggct cagtaatgtt gagtcccatg
     6181 atttcccagt gtccagtcat agtatcctta ccaagagata cttcctctaa ttttgttgca
     6241 tatccagttg gattgatttc agctgctaca gtcttaagag gagtttcacg aggaatattt
     6301 ccaagaccta ttttagccat gtttgggaca ttcaaaccaa ctgtttttga aatgtgtccc
     6361 agtgtgtcag aagctccatc tggaacccct gcattgacaa agttattagc atctggtgct
     6421 gcaccgattc ctacagaatc cagtaccacc aaatgaatac gattaaattt agacatctta
     6481 tgcccccttc tattttcctt tttttgaagt tgaaatctga actccatctc gtccagcaac
     6541 gattacctta tccaccattt ggttgaataa accatgctcc acaacaccaa cgacatggtc
     6601 caattcttgt ccaaaagcaa ttggattttc aatgacatcc aaggcgaggt caatgataaa
     6661 attctgcata tccgtcacaa aacgttggcc gtctttttca cggaaacttg gtttgtagcc
     6721 agctcgttca aaatgacgaa agacctgctc tgcaccatac tgaaccactt ctactggcaa
     6781 tttaaaagca cctagttttt cgaccagctt gctttcatcc accacccaaa tgtattcttt
     6841 tgatggtgtt gcgaccacct tttccatgag aagggcacca ccaccgcctt tgattccatt
     6901 aaactgacta tccacttcat ccgcgccatc aaccgtcaca tcgacaaagt ctacttggtc
     6961 aatagacttg agcgggatat taaggccttc tgcctgttta gtggtcacac tagaagttgt
     7021 tacagctgta atctgcaatc cttcttcctt gatacgacga ccgatttctt cgacaaaata
     7081 ataggcagtc gagcctgttc caagtccaac gaccattcca tcgctcacga actcagcagc
     7141 cttgatacct gccattttct tcagattttc caccgattta cctccatcat tctcagttct
     7201 tattttacta tgaaaccgct ttttattcaa gtaaaaacat caaatctaca tttttcatca
     7261 atctttcttt aaaaatatgc attttatttt taccaaacga ataaaaatga gtttatcttt
     7321 tatgtatttg atttgttcat ctctttccag ttacaaaaac aaactcttaa ctttgatacg
     7381 tctagtttag ccttaaagca ggcgcatttc aagaatcata aattaagaga aggaagtaga
     7441 tttatctgtc tattttaaac aagtttatct ttgcttaccc tctcttgttg acaaataatt
     7501 ttcattattt tgggaagata cctgctgatt tccgtcggta agaccacata attttcctga
     7561 gatagttctt gggctatggc tgaatgaaga tgggtcgcta ctgccacacg ctcgtagaga
     7621 ctggcctgtc ggaattggcc tacaaatcct gcgatcatcc cagccagagt atctcccatt
     7681 cccccagtcg cctgataagg accaccaacc tgtaactggt aataatcaga ttggccaact
     7741 tcccaaatac gagtagctgg gcctttctcc accaaaattg ttccttgagg gaaggaagtc
     7801 agaacactag ccgttgcatc ttccttttgc ttttcaatcg taattccaga taatttttcc
     7861 cattcttttt ggtgaggagt taggataagc tggcttgagg gaaatgacaa acttgtccta
     7921 gcaagaatgg tcaaggcacc tccgtctaca atcaaaatct gattttggct taaattaaca
     7981 aagacctgtt ttactagatt ttctccagaa gcatcgtctc gtaaaccagg ccccaacaag
     8041 acaacttctg ccttctccaa ttgctctttt aacaattgct ggtcttgaag agaaaaggcc
     8101 ataggctcag gtaaatggct gtgcagagcc gggatatttt ccctgtccgt tccaacggtc
     8161 accaatcctg caccgctttt tacagctgct aaagcagcca tgatgatggc acctccataa
     8221 ggataagtac caccaagcag cagcagacga ccataatctc ctttatgact tgaacgagaa
     8281 cgttcaataa taactttttc taataaggtt tgattaatca ctttcatcct tttttcctct
     8341 cacttttatt atacaataaa aaggagacgc agacctcctt ttgtaatctt atatctaaaa
     8401 tttaatattc atttctgcca ttttagatat agctatagaa aatacactct attaatcgaa
     8461 tgtttctctt attttctatc caatgtccga agtgctgctt gataagtttg ctccatcagc
     8521 atggtaatgg tcataggacc gacacctcca gggactggcg tgatatagct agcaagtggt
     8581 gcaactgcct cataatcaac atctccacag agcttcccat tttcatctcg gttcatccca
     8641 acgtcaatga caaccgcacc tggtttgaca aagtcagcag tcacaaactt ggcgcggccg
     8701 attgcgacta caagaatatc tgctttagca gccaccttgg caagattatg agttcgtgag
     8761 tgggtcaagg ttactgtcgc atttttagcc aaaagaagct gagccatagg ttttccaacg
     8821 atatttgaac gaccgatgac gaccgcattt ttaccttcca agtcaatccc atattcatga
     8881 aacatttcca taattcctgc aggtgtcgag ggaatcatga ctggatgtcc agaccaaaga
     8941 cgtcccatgt ttaagggatg gaaaccatcc acatcctttt ctgggtcaat ggctaataaa
     9001 accgcctctt catcgatatg ttttggtaat ggcaactgga ccaaaatccc atgccaagct
     9061 ggatcctgat tatatttagc aatcaggtct aacaattcct cttgagtaat ggtctctgga
     9121 actcgcacta cttcgctacg ggaaccagcc gcaagagctg acctctcctt gttgcgaacg
     9181 tagacttggc tggctggatt atccccaacc aaaatcacta ccaaaccagg cactagagct
     9241 gtttcttcct ttaattttgc agtcttttca gccaactgcc cctgcaattt ggccgctaaa
     9301 gctttcccat caataatctg tgtcatatca cttctctttt ctttcaaata tcttccatta
     9361 taccaaaaac tgctagtgcc ctctaacact tctttcctag gttatcctat agtttcaaac
     9421 tataagaaaa agctctggtt gaacttttca ctaatcttgt cttgaaattt taaaatagat
     9481 tataaaacct tactcaagaa atctttagtc cgttgttctt gggtttgttc aaaaatctgc
     9541 tcaggtgtcc catcttcaac aaccacaccg tctgccataa agataacacg atctgccacc
     9601 tcacgggcaa atcccatctc atgtgttacg ataaccatag tcatccctga cttggcaagg
     9661 tcttgcataa cagccaatac ctcacctacc atttcaggat ccaaggctga agttggttcg
     9721 tcaaagagca aaacatctgg ttccatagcc aacccacgcg cgatggcaat ccgttgttgt
     9781 tgcccacccg acagactctg tggataagcg tctgccttat ctggcaaacc aactttttcc
     9841 aaaagctctt gggctctctt ctcagcaact ttcctgcttt cacctttagt cttgataggt
     9901 gacaaggtaa tattttccat cacagtcata ttaggaaaga ggttaaattg ttggaaaacc
     9961 atgcccatct tctcacgcat ggcaaacagg tcattcttct tgtccgtaat atcgactccc
    10021 tcaaagataa ccttcccctt ggttgcttcc tccaacaaat tcatagagcg aagcaaggta
    10081 gatttcccac tccctgaagg accgatgata acgacaactt ctcctctttt aatctcgagg
    10141 ttgatgccct tcaatacttc attctttcca aaagatttat gtaaattttc aatttttatc
    10201 aaggtttctg tcattatttc ttatctcctt gtcccatatg tttttcaaaa gctttcaagg
    10261 ctactgtcag aatagaggtc ataatcaagt agtaaaatgc tgcaaataaa agtggtgtta
    10321 aaggtagata ggttgttgta gaaactgttg tagccccatt ccacaactcc atgaccccaa
    10381 tagctgataa gagggagctg tccttgataa tggtgataaa ttcgttcccc aatgctggca
    10441 agatattttt gactgcttgt ggcaaaatca cataacgcat cgcattttta ggacgaatcc
    10501 ctagcgaata agccgcctct agctgacctt ttggaaccgc attgattccg gcacgaacag
    10561 tctccgaaac ataagcacca ctattcatag agataatcaa aatccctgga atcagacgcg
    10621 aaaaatcaac acctaaaatt ccaatctgaa tagtcggagc attgatatgc ataagagcaa
    10681 aggcaatcat aatttgaacc atcatcggtg tcccacggaa aatccaaacg tacaagttgg
    10741 ccaaccaaac aagcggttta aactttgaac gttgcccaaa agccaagaca acacccaaaa
    10801 tagttcccaa aaagataaca cagatagaaa taagaatcgt cacaacagcc ccatagttaa
    10861 aataaggtaa atacttaggt aaaaaagaaa aattcatagt cacactgctt tctaaaatag
    10921 aatactgtat gattataaca tgttttgaat taaaatttaa attttttatc caatttattt
    10981 aaaaatcttt aaactagcag aattaacgag aaatcttagt tttttctagt caagttggcc
    11041 tcctttatgg taaaatagta acgataagaa atgaaggaga atcaaaatgg aatcacattt
    11101 ggttagaatc atcaaccgcc ttgaagcaat ggcaaacgat ggcggaaatt taaaacgtaa
    11161 ttttgaacgc gaaggagttg ttgttgcaga agttgcgtac agccacgacg aagaaaacgg
    11221 cccaatcttt acccttcgtg acgtagaaga tcgcgaaacg tatacgtttg atagcattga
    11281 cttaatcgca atggaaattt acgaacttct ctactaatct aaaacaagct gggattgtcc
    11341 ctgcatgtct aagtaaaatc ctttttgtct cacaaatagg atttttttat agtccaaatt
    11401 cacaaaaatt ttcattgtaa caacttctca aagcttcaat ctttttactt gctttacacc
    11461 ccaatcctgt tataatgaga gtatagaatt tgactatttt tgacctttaa acaagtcagg
    11521 ctaaagaaag aaatgaggta gatgtatgct ttgtcaaaac tgtaaaatta acgactcaac
    11581 aattcatctt tacaccaatc tcaatggaaa acaaaaacaa attgacctct gtcaaaactg
    11641 ctataagatt atcaaaacag atcctaacaa tagcctcttc aaaggtatga cggatctgaa
    11701 caatcgtgac ttcgatccct ttggtgattt cttcaatgat ctaaacaatt tcagaccttc
    11761 tagcaatact cctcctattc ccccaaccca atcaggtgga ggttacggtg gaaacggcgg
    11821 ttatggttcc caaaatcgtg gatctgctca aactccgcca cctagccaag aaaaaggcct
    11881 gctggaagaa tttggtatta atgtaactga aattgcccgt cgtggagaca ttgaccccgt
    11941 tattgggcgc gacgatgaga ttatccgtgt catcgagatt ctcaatcgta gaaccaagaa
    12001 taatcctgtc cttatcggtg aacctggtgt cggaaaaacg gccgttgtcg aaggtctagc
    12061 tcagaaaatt gtcgatggcg atgtgccaca taaactccaa ggtaaacaag tcatccgtct
    12121 ggatgtggtt agcttagttc aaggaacggg gattcgagga caatttgaag aacgcatgca
    12181 aaaactcatg gaagaaattc gcaaacgtga agacatcatc ctctttatcg atgaaatcca
    12241 tgaaattgtt ggtgctggtt ctgcgagtga tggtaatatg gacgcaggaa atatcctcaa
    12301 gccagccctt gctcgtggag aactgcaact agtcggtgct actaccctca atgaataccg
    12361 tatcattgaa aaggatgctg ccctcgagcg tcgtatgcag cctgttaaag tcgatgaacc
    12421 aacggtggat gaaacaatca ctattctcaa agggattcaa aagaaatacg aagattacca
    12481 ccacgttcaa tataccgatg ctgcgattga agcagctgca actctttcca atcgctacat
    12541 ccaagatcgc ttcttgcctg acaaggccat tgacctccta gatgaagctg gttctaagat
    12601 gaacttgacc ttgaattttg tggatcctaa agtaattgat cagcgcttga ttgaggctga
    12661 aaatctcaag tctcaagcta cacgagaaga agattttgag aaggcggcct acttccgcga
    12721 ccagattgcc aagtataagg aaatgcaaaa gaaaaagatc acagaccagg atactcctat
    12781 catcagcgag aaaactattg agcacattat cgagcagaaa accaatatcc ctgttggtga
    12841 tttgaaagag aaagaacaat ctcaactcat ccatctagcc gaagatctca agtctcatgt
    12901 tattggccaa gatgatgcag tcgataagat tgccaaggct attcgccgta atcgtgtcgg
    12961 acttggtacc cctaaccgcc caatcggaag cttcctcttc gttgggccaa ctggtgtcgg
    13021 caagacagaa ctttccaaac aactggctat cgaacttttt ggttctgctg atagtatgat
    13081 tcgctttgat atgagtgaat acatggaaaa acatagtgtg gctaagttgg tcggcgctcc
    13141 tccaggttat gttggctatg atgaggctgg tcaattaact gaaaaagttc gccacaatcc
    13201 atattctctc atccttctcg atgaagtgga aaaagctcac ccagatgtta tgcacatgtt
    13261 tcttcaagtc ttggacgatg gtcgtttgac agacgggcaa ggacgcaccg ttagcttcaa
    13321 ggatgctatc attatcatga cctcaaatgc aggtacagga aagaccgaag ctagcgttgg
    13381 atttggtgct gctagagaag gacgtaccaa ttctgtcctc ggtgaactcg gtaacttctt
    13441 tagcccagag tttatgaacc gttttgatgg cattatcgaa tttaaggctc tcagcaagga
    13501 taacctcctt cagattgtcg agctcatgct agcagatgtt aacaagcgcc tctctagcaa
    13561 caacattcgt ttggatgtaa ctgataaggt caaggaaaag ttggttgacc taggttatga
    13621 tccaaaaatg ggagcacgcc cacttcgtcg gactattcaa gactatattg aggacacaat
    13681 cactgactac taccttgaaa atccaagcga aaaagatctc aaagcagtta tgactagcaa
    13741 gggaaacatt cagattaaat ctgccaaaaa aactgaagtt aaaagttctg aaaaagaaaa
    13801 ataaatccta taaaaaaaga gtagaaaatg aaatttttct gcttcttttt ttactaaaat
    13861 aactgtaatt tcttgacagc ttgccctttg tccattatga
//
LOCUS       DAVKMJ010000045        13152 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000045 DAVKMJ010000000
VERSION     DAVKMJ010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13152
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.045"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            98..1276
                     /locus_tag="VW348_001703"
     CDS             98..1276
                     /locus_tag="VW348_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEU9746573.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDNYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(1504..1950)
                     /locus_tag="VW348_001704"
     CDS             complement(1504..1950)
                     /locus_tag="VW348_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9746574.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVQKYSRLKLE"
     gene            2020..2679
                     /locus_tag="VW348_001705"
     CDS             2020..2679
                     /locus_tag="VW348_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEU9746575.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACGIIFGKLLL
                     V"
     gene            complement(2731..3882)
                     /locus_tag="VW348_001706"
     CDS             complement(2731..3882)
                     /locus_tag="VW348_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEU9746576.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGNRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(3897..4628)
                     /locus_tag="VW348_001707"
     CDS             complement(3897..4628)
                     /locus_tag="VW348_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746577.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            4857..4958
                     /locus_tag="VW348_001708"
                     /pseudo
     CDS             4857..4958
                     /locus_tag="VW348_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(4930..5706)
                     /locus_tag="VW348_001709"
     CDS             complement(4930..5706)
                     /locus_tag="VW348_001709"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEU9746578.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLGETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(5699..6922)
                     /gene="trpB"
                     /locus_tag="VW348_001710"
     CDS             complement(5699..6922)
                     /gene="trpB"
                     /locus_tag="VW348_001710"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEU9746579.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGLGVDTEHHAATL
                     TKGCPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(6900..7499)
                     /locus_tag="VW348_001711"
     CDS             complement(6900..7499)
                     /locus_tag="VW348_001711"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEU9746580.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     YFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(7486..8253)
                     /gene="trpC"
                     /locus_tag="VW348_001712"
     CDS             complement(7486..8253)
                     /gene="trpC"
                     /locus_tag="VW348_001712"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEU9746581.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDC
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(8250..9254)
                     /gene="trpD"
                     /locus_tag="VW348_001713"
     CDS             complement(8250..9254)
                     /gene="trpD"
                     /locus_tag="VW348_001713"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEU9746582.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIITGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(9265..9831)
                     /locus_tag="VW348_001714"
     CDS             complement(9265..9831)
                     /locus_tag="VW348_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEU9746583.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGCAVMRYHSILIEEMPEDFEVTARSTDDQTIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEEVVK"
     gene            complement(9828..11189)
                     /gene="trpE"
                     /locus_tag="VW348_001715"
     CDS             complement(9828..11189)
                     /gene="trpE"
                     /locus_tag="VW348_001715"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEU9746584.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEELEKALNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPQKFEEMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(12110..13111)
                     /locus_tag="VW348_001716"
     CDS             complement(12110..13111)
                     /locus_tag="VW348_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEU9746585.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
BASE COUNT         3803 a         2958 c         2259 g         4132 t
ORIGIN      
        1 gtaagtaatg aaaagcttaa aaaaattaac atctacattt atccatagca aaaaatcata
       61 ggattttaag aatctgacaa ctaggaagaa aactaatatg accttatcta agaaacaatt
      121 acaactaaga gctaaaatac tggaaacagt ttacacatta ggtcccattt cacgaattga
      181 aatcgctact aaaacaggaa taacacctgc aacaactagc agtatcacaa atgatctgat
      241 taaagaaaat attctcttag aacttggtga agacgaacac gatacaagcg tagggagaaa
      301 aaaaatcctg ctagacattc aagctaaacg attttactac attggttgtg aactatctga
      361 aaaacatttc acttttgctt taggagataa tctaggaaat atcttaaagg aagagaaaga
      421 aattgttact aaacagttaa tccaagaaaa gggaaatcaa ctcattaacc agacactaaa
      481 gcaattctta aataactgct ctgattatga aatagaagca attggaatcg cgctacctgg
      541 tcgctattta gataattata aaataacaac aaacaatcct ttatggcaac atatcgactt
      601 agaaatgatt caatcccact ttgataagcc tttgtttttc tctaacaatg ttaactgtat
      661 ggctataggt aaacgcctat ttagtcgcca acagaatgac cctaattttg cttattttca
      721 ttttgctaga ggtatgcact gttcttatat ctacgacgga aacatttatg ggaaaggaaa
      781 tctaatgatt ggagaaatag ggcatacagt tgtttcatct gagggagaag aatgtagctg
      841 cgggcgcaag ggatgcttac aaacttttgc tggagaatct tggttaatca aaaaatcaaa
      901 aattctatat catcaatctc cctattctct acttcctagt ttagtcaaaa atgccgatga
      961 tattgatatc caagttattt taactgctta tcaattaggt gacactggaa taatcacact
     1021 tatccatcaa gccttactct atcttagtca aaccatttta aatatcagta tgatgattga
     1081 ctctcaaaaa atctacctac atagtccttt actaacaaat caacacatca tccaaaaact
     1141 atatagtgaa atgaactaca aacccaaact gctctataat cgcctacctg aagtcattat
     1201 tgaaccttac aatgatttta cagccgcaca ctcagctatt gcactttgtt tgtatcatac
     1261 aattctacat tcttaatttt ctattacatt taataaatag gctaaaaaga gggagtatat
     1321 cataaaaagc gaataaacct gttttctgaa aatcagaatt ctgttttgtt cgctttcttt
     1381 atatttggaa ttatactcct atctcccctt tttcataatg tatagtaaaa tgaaataata
     1441 acaggacgaa tcgatcggga cagtcaaatc gatttctaac aatgttttag aagtagaggt
     1501 gtactattct agtttcaatc tactatattt ttgtacaggt gcttcaacca tttgaacgat
     1561 ttcaaatcct tctttttggt aaagattctg agctctttga tttgcctcga agacatttag
     1621 agaaatacta tctatatctt cattttcaaa ggccaaacta acaaatttcc ttaaagcctg
     1681 gctacctaag tcttgctcct gtttctgggg gttgataaaa aatctcccga tatgaagatt
     1741 gctgtcttct agcctgattt tctggataag tcccacaaac tcttgttcat caaagattga
     1801 aaagactcct tccaaggctt gaagggtcag tagaaaagga atccttggtc ccatccattg
     1861 ttcttgaaag gatttgccta gggagttgga ccactggcat acaaattgag cgttttctat
     1921 actcaccttt tcttcaaaac gaattgtcat cttttcctca ccatcttatc tatgtttctc
     1981 cattatacta tttctcccat tttttacgaa tagataagta tgattgattt ttattttttt
     2041 ctcgtcggga gcattctcgc ttcctttctt ggtttggtca ttgaccgttt tccagagcaa
     2101 tccattatca gttcagccag tcactgcgat tcctgtcaga ctcgcttgcg tcccttagat
     2161 ttgattccga ttctctcaca ggtcttcaat cgctttcgct gtcgctactg caaagttcgc
     2221 tatcctgtct ggtatgccct ctttgaatta gtcttaggac tcctctttct gctttactct
     2281 tgggaattgc tttccttggg gcaagtcgtc ctaatcaccg ctggtttgac cttgggtatc
     2341 tacgactttc accatcagga atatccctta ctggtctgga tgactttcca cctaatccta
     2401 atagcttcct ctggctggaa tctggtcatg gtctccttcc ttgctcttgg aattttggct
     2461 cattttatcg atatccgcat gggcgcaggg gatttcctct ttttagcttc ttgtgctctc
     2521 gtctttagcg taacggagtt actgatcttg attcagtttg cttctgcgac gggtatcctg
     2581 gcctttctcc tgcaaaagaa aaaggagaga cttcctttcg tgcctttcct cttacttgct
     2641 gcttgtggga ttatttttgg taagctactg cttgtctgat aaaatccaat ttctgccata
     2701 tgtccttcat gaaattattt cacagttaaa ttataaatta tttcttttgt acaaagggat
     2761 gatgttatca aatcgatctg ttcttctatc ttcttgatac tgatcaaaaa atttcatttc
     2821 gactgaaaat atttcgctta taaactgtaa acgaatactt tgtttagaca ttatagtcgc
     2881 tagactgact agatgattac tcaaaacgac gtccagaata ctctttactt tgcttggttt
     2941 tttaacaaaa atttgatcat ccaaaggttc aatcattttg taaccttttt gcgcaatttg
     3001 acgataaaag taagaatgtt gctttggagt caataatcct aacttaaaag ctcgatactc
     3061 taaagcctgt atcgaaacat tcaaatccga cttcaataaa atataactat caggattgct
     3121 gacacgcttg ccaaccctct cttcaaattt gactaaaaac tcttcttttg gcaataaaaa
     3181 acatgatgca aaataatttg cttcttgctc caaacgattg ccatcttcat tcatatcttt
     3241 atatttatgt aaaagaatat gtcctagctc atgagctaag tcaaaatttc gacgtacaga
     3301 tgatttattc gttcccaaca caatataagg tcttcccaat tttgaccatg cgctataagc
     3361 atcagcttgg ccattaatta atcgttccac gatatagata cctgaacgtt ctaatttata
     3421 aagcaaatca tgattatctt ttgaaatacc taatttttcc ctggcataaa gagccaattc
     3481 ctcaatggat tctcccttat gataagattc actcactaca ttacttaggt catgaattat
     3541 aatattaggt ataattacaa aactttcaaa ataatcaatc aaactatcta ccttatgtaa
     3601 atacatagtt tgaatatcta ttgttttccg tgttgctagg tctgcatttc taaaggcaat
     3661 tacagaagaa tcaaatcgaa tgctctcttc ttcctgttca aaataagtta aatcaacatg
     3721 aaattggttg gccaaatgca ttttggttga taatttaggt ttcgtttcgt tggactcaaa
     3781 ctgccaaatg gcttgttccg ttaaattaat tctctgagct aattctgctc tacttaaacc
     3841 atttaacagc cgtaattctt tcaatacccg accattaaac atttatatac tccttactac
     3901 ttttgacctt cttgtttttc tattcttgga ataatttcaa aatcttctgt ttccgataat
     3961 tctgaaaaat taggaatatc ttgatattta gcttcttcga aatggtacga acttgattga
     4021 atatactcag acaaatcttg aatcaagtgt agctgaccag ttcgtgcatc aggcataaca
     4081 acatctacag atataatatt gttttctgag tccgcctcat aagttaaaat cataaatttt
     4141 tcgatattcg aatttttagt agcttgttca atttcttgaa tcatttcatc agaaactaac
     4201 tccatctgaa ttggaaagga atgactatct tcatcatttt tgtaggaaga atgttgatta
     4261 agataaagtg tattcatctg agcgtattca aataagtagc cactcttatt tttttgtacc
     4321 aaaggaaatt ggttcgtaag tcgcttctta ccctttataa ttaacaatac tttcccatat
     4381 ttttctgtat ttgtttcaaa ttctaaatat ccccaagtct gtcctgctaa ttgtaattta
     4441 tactcaaaca aatctgctga tgcaaatgca gtatcaatat gattaggtcg cgtccatgca
     4501 taaccattcg acactatcat tgtctctctt ttttctagac gttcatctac ataatctttt
     4561 tgccctttca tcaaagtatc tacaattttt tgtgcctcaa gcgaatcaaa gagatcctga
     4621 ttcaacataa ttcttcctcc tccaaatact ttttaatgaa ttatatcatt ttcttaaaga
     4681 aattactaca ataattatct ttttcttaaa gttctgtgtc agagtaattt agaaaattat
     4741 atcttctata gtaaaatcaa ttaaaaactg aacaaattta ttgggaaatt caaatcgctt
     4801 tctgaaaata ttttaggaac cgtagtgtaa tattccagat tcaattcact ataaaactga
     4861 cctttctcct gcaaaagaaa aaggaaagac ttcctttcgt gcctttcctc ttacttgcta
     4921 cttgtttgat tatttttggt aagctactgc ttgtctgata aaatcctgaa tcggctctcc
     4981 ttggtggaga gcttttacta tttttgaacc gacgataaca ccatctgaca ccgcattgaa
     5041 gcgttccaga tcggcttgac tagatacacc aaaacctgtc aagactggga tgtcggccac
     5101 ttgatgaagt tgcgccaagt gcttgtccaa atctgcacgg taattgcctg atttccctgt
     5161 caccccattg atggcaacgg catagacgaa tccctccgcg ccttcaatca actctttctg
     5221 gcgctcaatt cctgtggtca agcttactaa aggaatcaag gcgatatctg tatctgccaa
     5281 aaatggttct acaaagttgg catgttcatg aggcaagtct gggataatca agcccttcac
     5341 agctgtatca gccagatctt tgacaaagtt ctccacaccg tactgaaaga gggggttgaa
     5401 gtaggtcatg atgaccagtg gaatctctgt ttcaatggtt ttcaaggttt caactaaagc
     5461 ctgggtagag gtcccgtggg ctaaactgcg caagccagct tcttcgataa caggtccatc
     5521 tgcaacaggg tctgaaaagg gaatacccac ttcaattgca gagacaccca aatcttctag
     5581 aaagtggatt gtttctccta gtccatccaa acctttctcg tggtctccag ccatgatata
     5641 gggaacaaaa attccttttc cagctgcttt aatagcattt aatttttttg ttagtgtctt
     5701 aggcatgagc ttctcccttc tttgctgcat ctgcttccaa gcggtctttg acttgaacca
     5761 catccttgtc cccacgacct gataggcaga caatcataga cttttctggt ccaagttctt
     5821 tggccaattt caccgcaaag gcgatagcat ggctagattc caaagctggg ataatccctt
     5881 ccacacgaga caagagttgg aatccttcca aagcttcttc gtctgtcaca gggacatagc
     5941 tggcacgttt aatatcgtgg tagtgagaat gctctggacc gataccagga tagtccaaac
     6001 ctgctgagat agagaaggct tcaagaattt gaccatgggc atcttggagc acatccatga
     6061 gggaaccgtg aaggacacct ggacaaccct tggtcaaggt agctgcgtgg tgctccgtat
     6121 ccacaccaag tccagccgct tcagctccat acatggctac tgactcatct tctacaaagg
     6181 gatggaagag accgatggca ttcgacccac caccaacaca ggctactagg gcatctggca
     6241 gattttgtcc tgtcaagtca cggtactgtt gtttagcctc tcgaccaatg acactttgga
     6301 agtcacgaac aatttctgga aatggatgag gccccaaggc agaaccaaga atatagtggg
     6361 tatcatcgat attagccacc catgaacgaa gggctgcatt aaccgcatcc ttgagcacgc
     6421 gcgaaccatc tgtcacggcc tcgaccttag ctcccaaaag ctccattcgg aagacattga
     6481 gggcttggcg tttgacatct tcctcaccca tgtagatggt acattccatg ttaaagaggg
     6541 ccgcagcagt tgcagttgcc acaccgtgct gaccagcacc cgtttctgcg ataattttct
     6601 ttttacccat gcgtttggca agccaaactt gtcctaaggc attgttaatc ttgtgggctc
     6661 ctgtatggtt aaggtcttcc cgtttgagat aaatcttggc tccgccgata tgctgggtca
     6721 agttttttgc gtaataaaga ggagtttcac gtcctacgta ctggcgcaaa agctggttta
     6781 attcctcttg gaaacttggg tctgcctgac tttcacggta ggccttctcc aactccaaaa
     6841 ctgctgtcat caatgtttct gggacaaaac gtccgccgaa ttttccgtaa aatccatctt
     6901 tatttggttc ctgatatgcc atgctttacc ctctctataa atcttctaat cttttcatga
     6961 tctttttgtc catctgtctc cactccgctc gatacatcta ctgcataggg agtaaaatat
     7021 tgaattgctt ttactacatt atcttcatta aggccacctg cgataaagaa gggctgtgct
     7081 agtccagtcg tatccagttg accccaatca aagggctggc cacttcctgc cacaggggca
     7141 tcaaagagta gataatctgc ctgagaatta gggacatgcc catttccatc tacctgcaca
     7201 gcctgaatac tggcacaagg caaattctca aataaatcat ctgccacctg accgtgaact
     7261 tgaaccaagt ccaagccaac tttgtcaatc gcttccagca gttctacccg acttggtgaa
     7321 acaaatactc caaccttttt cacatctgca ggaataagct ttgccaactc agctgcctct
     7381 tctaaagtca cctgtctttt actaggtgca aagacaaaac cgatatagtc ggctcctgct
     7441 gaaacggctg tttccaccgc ttctttggtc gatagtccac aaattttaac ctttgtcaat
     7501 ctgcaactcc ttgattctct gggccacatt ttctgcctgc ataagagctg tccctaccaa
     7561 aattccgtta aagtatgggg ctagtcgttc cgcatcctgc cctgtgaaaa tggcagattc
     7621 agaaatgtaa tagcgacctt cctcaaagta aggggctaaa tctacactgg tctgcaagtc
     7681 gacctcaaag gtagtcaagt tgcggttgtt gaccccgata atctcagcac caagtctgtg
     7741 ggctacctct agttcagcta gattgtgagt ctccactaag acttccagac caagctctgt
     7801 cgcgtagtca tacagttcct tgaggcgttc ttcggacaag gctgccacaa taagcaagat
     7861 aactgtcgca cctgcattgc gagcgcggat gatttgcttt tcatctatga taaagtcttt
     7921 gttgagcgtc ggaatctcta cctgactgga aatttcccgt agataatcca aatgcccttt
     7981 aaagaaaacc tcatctgtca acaccgaaat catcactgct ccgttttctt cataagtctg
     8041 ggcctgttgc acaatatcca catcgagatt gatatctccc aaactagggc tagctttctt
     8101 gacctcagcg attacctgca agcagtcctg atgattcttc aaaaattctg ccaagcgata
     8161 ggtctggcgc agaggctgga tttgctccag cttcatctgc tccacctcac gcgccttctg
     8221 ctctaagatt cgtgctaaaa attcctgact catttttggt actcctgtaa cagtctgagt
     8281 ttttcaaggg ccttgcctct agcaatcact tgacgggcca aggcaactcc ttccttgatg
     8341 ctatcaatct taccattagc atagaaacca agaccagcat tcaagactgt cgtttccaag
     8401 aatggacttg cttcgttttt cagaacgcta agcaaaattt ctgcattttc ctgagcattc
     8461 cctccacgaa tatcttccat agcatagcct tccattccca aatcctctgg agtaaagctt
     8521 gacaagctga tttcgccatt ttcaagaagt gcaatcttgg ttgttccgtt caagccagct
     8581 tcatccaacc cttctggtcc agcaaccacg atggcacgtt tgcgacccat atttttcaaa
     8641 acctgagctg tactttctag gagttctgga cgactaattc caagaagctg tgtttctaaa
     8701 gccattggat gaatcagtgg accagtcaag ttcataatcg ttggaattcc caattccaaa
     8761 cgagctggca tgatgtattt catagctggg tgcatatttt tagcgaagag aaagacgatg
     8821 ccagttttat caaagacctt acctagttca gctggtttga ggtcaagatt gattcccaag
     8881 gcttcgagga catctgcgga accagattta gaagaaatcg agcggttacc atgcttggcc
     8941 atgtgaatac cgccaccagc caagacaaag gctgcagttg tggaaatatt aaaactgaaa
     9001 gacttgtccc cacctgtacc acaattgtcc atggcatcat gaatctcagt tggaatatgc
     9061 tgggcatgtc ctctcatgac ttgggcaatg gctgtgcgtt cttcaggtgt ttcccccttc
     9121 atcttaagag ctaagaggag agaagcaatc tgcgcttcag ttacacgccc agttatgata
     9181 cgctcaatga catccgtcat ttccacacct gataaatttt caaattttgc tagtttttca
     9241 ataatctctt tcatcctagt ttcctcactt tacaacctcc tcgataaaat tccgaataga
     9301 agacaagccg tctggcgttc caatgctctc tggatggtac tggaagccat aaatcggtag
     9361 gtttttatgt tgaatcccca tgatggtttg gtcatcagtc gaacgagctg tcacttcaaa
     9421 gtcttctggc atttcctcaa tcaaaatact gtgataacgc atgaccgcac atccatcctc
     9481 aataccttga tacaaaacag atggcgcttc aaagttgata ttgctctgtt tcccatgcat
     9541 gacttttgga gccaaaccta gcttaccacc aaagacttct gcaatggctt ggtggcccaa
     9601 acaaatccct agaatcggct tcttgcctgc aaaatcacga atcatgtctt ccatctttcc
     9661 agcatcaact ggccaaccag gaccaggaga aaagaccaga ccatctgctt tttcagcttc
     9721 ttcatacagc ttggaatcat catttctcag aacctgaact tctgcaaaat tcccaatgta
     9781 ttgggccaag ttataggtaa aagaatcata gttgtcaatc aataaaatca tggtcttagt
     9841 tctccaattc tagtcataga ttttgctttg ttaatggttt cttggtattc gttttgggcg
     9901 atagagtcgt agacaatccc tgccccagcc tgcacatagg ctctttgatt tttgagaatc
     9961 atggttcgga tggcgatggc caaatccata tcacccgtcg cagacaagta gccgattgcc
    10021 ccagcgtata ctccccgttt ttccgtttcc agttcataga tacgtctcat cgctcgaatc
    10081 tttggcgctc cagaaacggt tccagcagga agcgttgctt tcaaggcatc catggcagtg
    10141 agttctgcaa gcaaacgtcc cttgaccaca ctggtcaaat gcatgacgta gcggaagagc
    10201 tccacctcca tatacttagt aacttggaca ctggccgttt cagagatgcg gccaatatcg
    10261 ttacgcccca agtctaccaa cattcgatgt tctgctgttt ccttctcatc agagaggagg
    10321 tcagtcgcca aggccttgtc ttcttcatcc gtagcccctc ttggtcgcgt ccctgcaatc
    10381 ggattggttg tcacgatgcc atttttgaca gaaaccaaac tttctggact agctccgatg
    10441 atttgataat ccccaaaatc atagaaataa aggtaattag aaggattagt tacgcggaga
    10501 tttctgtaga agtcaaatgg atttccagta acttctgctg agaaacgctg gctgagtaca
    10561 cattggaaca tatcaccatt acgaatcaag tcacgagctg tttccaccat ttcctcaaac
    10621 ttctgaggag cgatatgcgg tttgaagtct aacggagata gatccaagtc ttcaaactca
    10681 tttggagcag gaatgcgtaa ttcctcaagc acttggttca aggctttttc caattcttct
    10741 tgactacgct cactatagag agcatcctcg atgacatgta tcttctcctt cttgtggtca
    10801 aagaccatat agctctcata gacaaagaaa tgcatgtctg gcgtcccaat tgtatcctca
    10861 gggatttgac caatttcttc ataaagcgaa atcatatcgt aacccacaaa accaatggct
    10921 ccaccaccaa aagggagctc tgagtggtgc tgactcttat gaatcacttc ataaaggaaa
    10981 tccaagggat cccgatcaat cacttgacca ttttgataga gaactccatt ttcaaactta
    11041 atctcaaaaa ctggattata ggctaggata gaaaaacgag ccgtttcctt gtctctcgga
    11101 atactctcta aaataacctt atgttgcccc tttaagcgca tataagccaa gattggtgat
    11161 aagacatctc catgaatgat tcgttccatt gtaatttccc tttcagttct aattctagtt
    11221 cgtggcgact gtatgaaaaa tccccacgca aaataacttg cgtgaggacg aaattcgcgg
    11281 tgccacctca attataggat ttctcctatc tctcattcct gtctcagata cctcctgtaa
    11341 caggctgtgc gataaagggc actcccttga gaatgatgtt ttcttctctc gtttcagatg
    11401 aacccaactt tacagctttc tctgcttgtt ttcagcaacc acaagctctc tgtgagagaa
    11461 aagactgtaa tttttccatc tattattttt tagcttctag taatctgcaa tcgcagctag
    11521 gtccttgcct ccacgaccag agacattgat gaagagatgt tcatctcggt acacctttat
    11581 actcttcgaa aatctcttca aaccgcgtca acgtcgcctt atcgtaggta acgacggata
    11641 gaaaaaagcc cacacacaga atatacttcc gtgtgagggc gttggtaacg cggtgccacc
    11701 tcaattataa agggactatc cctttacatc tctgccttgt ttaacaacaa gctgcactgt
    11761 aaggtgtgcg caccgaattt tcattgtttc aaattcattt tcaaaatcag cccactttca
    11821 ctacttccaa ccacctattc acaatcacca caggctccct gaagatcaaa aatagttact
    11881 tttctgattt gttgaactta ttttaatact ttgttttttc tttgtcaaga cttttttacg
    11941 atttttttga tatcattcga atgtgaccat atcttcctta gatcgaacat gaacatgtcc
    12001 cacttgttag aaattggatc caactcaata gaaactgaat ggaggctaaa cagaacttat
    12061 tttagaacac tccatctttt ccactaggat tttcaagaat taaacaatac tagaaactct
    12121 gtctcctaac aaatttagga gaaacttcaa cagatgtgac actttcccct ttaataattg
    12181 ctaaaacacc ttctatcatt tctttagcca atttaacata attgggagca attgtagaca
    12241 aagctggagt ataatactga gaaataggaa tattatcaaa tccaatgata gaaatatcat
    12301 ctggaataag aattcctttc tcatagcacg cacgaatcaa gccctgaacc ttttcatctc
    12361 ctgaaacaaa aataatgtcc ggataatttt gggtagtcaa gtgctgcatt gcataagaat
    12421 aaactgaatc aattgtagat aagccataaa tgacttttaa atccataaag taatttttat
    12481 cattcagaaa agaacgcaca cctctttcac gatccttatt aacatgagat tctcctccca
    12541 taagcaacca catattttta aatttttctt cagttacagc tttcatcata tcataagtag
    12601 cttgaaaatt attattagat acatagacta ctccagacgt ttgagattca ccgaaaacaa
    12661 gaaaaggcat atggttcttc tttaaatact gaattctgat atcatctaca ctttcataaa
    12721 aaacaataac accatctact aggctacctg tgcttgatat aattgaatta ctaattgtat
    12781 cctcctctcc aaagtactca actatagcat taacaccaaa ttctttacac gtccgtaaca
    12841 ctttatctaa cagcgtatga aaccaaatta aaggaaaaga gtcgattttt tttacagaaa
    12901 tcaatatatt tatagcttct tttttagtta aattttttgc atacgcattt ggaatatacg
    12961 acaattcctc tataactttt tgaatcgctt gataagtttc ttctttaaca tttactccac
    13021 cattaataac tcgtgaaact gtttttggag aaaaacctga taaacgtgca atatcataaa
    13081 tagttacctt tttcccattt atatttttca tttcagtcct ccattacgaa cattctaata
    13141 ttactataca at
//
LOCUS       DAVKMJ010000046        13092 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000046 DAVKMJ010000000
VERSION     DAVKMJ010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13092
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.046"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..1101
                     /locus_tag="VW348_001717"
                     /pseudo
     CDS             1..1101
                     /locus_tag="VW348_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(1187..2389)
                     /gene="rpsA"
                     /locus_tag="VW348_001718"
     CDS             complement(1187..2389)
                     /gene="rpsA"
                     /locus_tag="VW348_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEU9746586.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFVDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRVARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            complement(2551..2622)
                     /locus_tag="VW348_001719"
     tRNA            complement(2551..2622)
                     /locus_tag="VW348_001719"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2588..2590),aa:Gln,seq:ttg)
     gene            complement(2632..2712)
                     /locus_tag="VW348_001720"
     tRNA            complement(2632..2712)
                     /locus_tag="VW348_001720"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2676..2678),aa:Tyr,seq:gta)
     gene            complement(2762..2992)
                     /locus_tag="VW348_001721"
     CDS             complement(2762..2992)
                     /locus_tag="VW348_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEU9746587.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            complement(3160..3804)
                     /gene="pcp"
                     /locus_tag="VW348_001722"
     CDS             complement(3160..3804)
                     /gene="pcp"
                     /locus_tag="VW348_001722"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEU9746588.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            complement(3819..4742)
                     /locus_tag="VW348_001723"
     CDS             complement(3819..4742)
                     /locus_tag="VW348_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEU9746589.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            complement(4739..5428)
                     /locus_tag="VW348_001724"
     CDS             complement(4739..5428)
                     /locus_tag="VW348_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEU9746590.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            complement(5493..6197)
                     /locus_tag="VW348_001725"
     CDS             complement(5493..6197)
                     /locus_tag="VW348_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEU9746591.1"
                     /translation="MVLSTLAILVACGKTDKEADAPTTFSYVYAVDPASLGYSITTRT
                     STTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPIVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKHIK"
     gene            complement(6253..7275)
                     /locus_tag="VW348_001726"
     CDS             complement(6253..7275)
                     /locus_tag="VW348_001726"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEU9746592.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            complement(7405..9876)
                     /gene="parC"
                     /locus_tag="VW348_001727"
     CDS             complement(7405..9876)
                     /gene="parC"
                     /locus_tag="VW348_001727"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEU9746593.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLRIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKNFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEAILYVEVLDQFDDATTYFAATRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            complement(10296..12239)
                     /gene="parE"
                     /locus_tag="VW348_001728"
     CDS             complement(10296..12239)
                     /gene="parE"
                     /locus_tag="VW348_001728"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEU9746594.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTALKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            12375..13016
                     /gene="plsY"
                     /locus_tag="VW348_001729"
     CDS             12375..13016
                     /gene="plsY"
                     /locus_tag="VW348_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEU9746595.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
BASE COUNT         3796 a         2962 c         2306 g         4028 t
ORIGIN      
        1 gaaagcgtcg tttcaagtgc tatcactgtt caaaaatgat ggttgctgag actcccctgg
       61 taaagaaaaa tcaccaaatc cctcgtatca tcaaccaaaa gattgctcaa aagttaattg
      121 aaaagatttc tatgaccgat attgcccatc agctttccat ctcaacttca actgtcattc
      181 gaaagctcaa tgacttccac tttgagtgta attttagaaa tctgcctaag attatgtctt
      241 gggacgttga aacagtccgg ggagtgactg tttcaatcgg gagatggaga tgagctttat
      301 tgcgcaagat tttgaaaagc tcgatatcat cactgttctt gaaggtagaa cacaagctgc
      361 catccgagat cactttctta aatatgatag agccgtccga tgtcgcgtca aaatcattac
      421 tatggatatg tttagccctt actatgactt ggctaaacag cttcgctttc aaatttctag
      481 gctcaggctg aaacagtctc ccagactgtt tcactcccga atgctgaaat cgttcttgat
      541 cgctttcaca ttgtacaaca tcttagccgt gctatgagtc gtgtgcgtgt tcaaatcatg
      601 aatcagtttg aacgaaaatc ccatgaatac aaggctatca agcgctactg gaagctcata
      661 caacaggata gccgtaaact gagtgataag cgattttatc gtcctacttt tcgtatgcac
      721 ttaaccaata aagagatttt agacaagctt ttgagctatt cagaagactt gaaacaccac
      781 tatcagctct atcaactctt gctgtttcac tttcagaata agaaaccgga gaaatttttc
      841 ggactcattg aggacaatct aaagcaggtt catcctattt ttcagactgt ctttaaaacc
      901 ttcctcaaag ataaagaaaa gattgtcaac gcccttcaac tacactattc taatgccaaa
      961 ctggaagcga ccaataatct catcaaactt atcaagcgca atgcctttgg ttttcggaac
     1021 tttgaaaact tcaaaaaacg gattttcatc gctctgaata tcaaaaaaga aaggacgaaa
     1081 tttgtccttt ctcgagctta gctttttttc aacccactac agttgacaaa gagccagaaa
     1141 aatcctttgt ttagtaaaca aaggattttg tgaattttca atttgattaa agttcgatat
     1201 caccaaacaa atcagccatt gaaaatcctg tttgtgtttc tggaagttcg aaatcacgct
     1261 tttcttgacg tcttggacga cgtggacgag caacacgttt ttcttctttt tgtccttctt
     1321 cttgggctgg acgttcttca agagctttaa tagaaagtga cacgcgttct gcatctgcgt
     1381 taacttcaag aactttaact tgaacttctt gaccaacttt aagagcttct tttggatttt
     1441 caatccgttt gtgtgaaatt tgtgatacgt gaacaagtcc atcgatacct ggcaatactt
     1501 caacaaatgc accgaagtca gtcaaacgtt taactgttcc ttctactaca tcacctttag
     1561 ccaatttttg ctcaacgcca tcccatggtc ctggtactgt tgctttaagt gaaagtgata
     1621 cacgtccttc ttcttcgtta agatcaagga ttttcacttc aatttcttca ccaacagtta
     1681 caactgattt tggtgataca ttacgttcat gtgacaattc agtcaagtga accaatccgt
     1741 caacaccacc aagatcgacg aaagcgccga agcttgtgat acgagcaact ttaccagtta
     1801 caacatcacc aacagccaat ttaccgaata cttcagcgcg agctgctgca gtagctgctt
     1861 caacaacttc acgacgtgaa aggatgaagc ggttttcttt agcgttaact tctttgattt
     1921 tagtatcaaa ttcttgacct acaaaacgct cagcgttacg tacgaaacga gtatccaaca
     1981 ttgaagctgg gataaatcca cgaacacctt caaattctac tgaaagtcca cctttaacgg
     2041 cacgcgttcc tttaacagta acaacttctt cttcgcgacc aacaagtttg tcccatgctt
     2101 tgcgagcttc aaggcgtttt ttagatacaa ggtatgtaac tgtatcagta tctttaccaa
     2161 ctacttgacg aagtacaaga acatccaata cttctcctac tttaacaaag tcattgatat
     2221 ctgcatcacg atcgtttgtc aattcgcgaa gagtcaagac accttcaaca ccagttccag
     2281 agattgcaac gttagcttga gtcgcatcaa ctgtcaatac ttcagcacta acaacatcac
     2341 cagtctcaac ttgactaacg ctatttagca aatcttcaaa ttcattcatc taaaaaatcc
     2401 tccaacaatc aagtttttct taaacttgac atacttataa tttttttcct aagcacccgc
     2461 aaggacatgt tcatatcatt cacgtctttc aattataaaa ataaaatacc ctaagatatt
     2521 ttgcttttta tcttgattat tacctaagaa ctggggtagc tggattcgaa ccaacgcatg
     2581 agggagtcaa agtcccttgc cttaccgctt ggctataccc cattaatgaa atggagagag
     2641 agggattcga acccccgaac ccgaaggagc ggatttacag tccgccgcgt ttagcctctt
     2701 cgctatctct cctacaatca acatggacta ttatatcatg aaaatttcaa aaaaacaaga
     2761 cttattttgc taaattataa ttttcaatca aaatttccac agctttttcc aattttttat
     2821 aaaaactatc gacattccca ttctttataa tggcaaattg tccgtctaat tcggcaattt
     2881 ctccgataac ttttttaccg atagtcaatg tataaccttc aaaactgtct ttaccaacat
     2941 taactttggc atccgctact tgaatttcga tttttttatc tttcttgctc atttcatacc
     3001 tctcttcact ttttctattt tacaagaaaa tcctaaaact agcaagaaaa aactctatat
     3061 caggcttctc tgatatagag ttttatgtaa acaacctcaa tcgatttagc atagttaata
     3121 gttagtaaac aagcataatt gactatcctt tttaggttat cagtgagtct caccgcctac
     3181 taactgcaaa tccttatctt tgtagtctac aatagcttca atagctacct ctatgcctct
     3241 tacaatatca catagactca ttcctgcagt attcggctta tttactactt gttccatcat
     3301 atatggaata tgcatgaaac ctgctctcat attagggaat tttttatcca ctaaataaag
     3361 agcttggtac atcaaatgat tgcaaacaaa ggttcctgca ctattggata caactgccgg
     3421 aagtccctgt tttttgatag cttgtaccat cgctttgata ggtaaactac taaaataggc
     3481 cgatgctcca tcaatacgaa tcggtgtatc aattggttga ttgccttcgt tatcaggtat
     3541 gcgagcatca tcttgattaa tagccactcg ttcaggtgtt aagccggtcc tgccgcctgc
     3601 ttgtccaata caaagtacag catctggttg atatcgtaat atttctgcct ctaaaacttc
     3661 tgacgactta taaaaaaccg ttggaatttc tacccagcga acttcagccc cattaatctc
     3721 agatggtaat aattttacag cctccaaagc tggattaatc ttttcacctc caaaaggatt
     3781 aaaacctgta accaatattt tcattttatt ttcctttact aaaatgcgag aaagtacatt
     3841 aagaatatgt gaataacaat cattactaga gcaacacctg cttgagcctt tataacgcca
     3901 ttctgatctt tcatatccat caatgctgct ggtagagcgt taaaattagc agccattggg
     3961 gtcaataagg tcccacaata acctgctgtc atggcaagag caccagccac aattggatta
     4021 gctcccagag caaatacgaa gggaactcca acacctgctg taataacggt gaatgctgca
     4081 aaagcatttc ccataatcat tgtgaataga accattccaa gaacataggc caaaactcct
     4141 ataaagcgac tatctgaagg aacaataccg ctaatcagat gagagataac atcaccaaca
     4201 cctgctacag taaaaatagc ccccaaagcc cctaataatt gaggaacaat cccacttgtt
     4261 gaaacttgct gagtcattcg attattttct gataacagac tcttagggtg actattggta
     4321 atcacaagaa cagaaattgt agcaaacaag gcggcaaggc taatcgaaat cttgctaaat
     4381 tctggaatca tttgcgctaa gaccaacgca agtattgcca tcagcataac tggaataaaa
     4441 attttatttt tcaacctgtt agattcaata ttggctttca tttcatctaa ggatggcaag
     4501 gttccgatac ggacttgctt aaacaatgtt aacagcgata ataggattac aataatacca
     4561 atactcatat ttggcatata ggaaccacct ataaacgtaa tagacaatag agtccaaaat
     4621 gcagatgtcc caagtcgaac tgggtttgtt ttatctttat aactacaata ggctgtatgg
     4681 agaaattgac aaccaatcac aatataggtc aactctaata gttgctttgc caactctgtc
     4741 atttttgttc tcctccccta gtcttttttg atatcaattt tttatcaaat aaataattgt
     4801 aaatccccac tacaataagt gttataacag caacaataat agatgtagaa gcaatccctg
     4861 cataattgct ttcatagcct aactgatcta atgttccccc tatcaagagg actcccccag
     4921 cacctacaaa cgtattttga gcaaagaaat ttccaaaatt ttcattcgca gccgcacgcg
     4981 cttttattgt ctcatcttca acctctgtta actttctacc taattgagac tctgcagctg
     5041 cttctcccat aggttgaacc aaaggtctga caaactgagg gtgtcctcct agacgaattg
     5101 aaaagaaacc agctaactct cgaataaaga aataaactgt atagaagttt ccaactgtca
     5161 gacctttaat ctttcgaatc aaatcgattg atcgttgctt gagtccaaag gtttctgaca
     5221 gccccacaag aggcaaggta accataaaaa tcgtgagcac tcgctgattg ctaaattctt
     5281 ttcccaaaat ctccaaaaat tcaacgagag aaacacctga aactaaagct gtaaccaaac
     5341 cagctaagac tactgttgca attgtatcaa attttaaaat aaaacccaca acaatgattg
     5401 ctattcctat taatctaatc cactccatat caaactcctt tatattcaaa atgacagtat
     5461 tttaaaaatt ttatcaagat caataccatt ccttatttaa tgtgtttttc tagttctttt
     5521 tggtatttgc tattggattc caatttttct ttttgccatt ttttaaaaac ctcgttatat
     5581 tcttttgttg taacaatatc tttttgcaat ttcattcctt taaagatata tggttccccc
     5641 ttaataccaa cttgtgagta tggttttgag aatggtacta cgttacttac aattggagaa
     5701 ccaccagatg aagctgttgg catcaataat gaactatctg tcgaccaagc ttgagctttg
     5761 gcatattttt catatctctt ctctaggtca gtggtctcag aaacagcatc ttctaacaat
     5821 ttcttatatt tatccaaacc aggtttagct acaacatcct tatcttttcc tttcgtaata
     5881 ccaaggtgtt tcatggcaga accagatttt ggatccataa tattcaagta agacgctgga
     5941 tcttgatagc ttggagccca tcctgtacta ttcaaatcat agtctttttg agaaggagca
     6001 acattgccgt atttatcatt ttccatcaaa ccatcaataa catttccaat aacgtctgtc
     6061 gtcgatgttc gagtcgttat actgtagccc aatgatgctg gatctactgc atagacataa
     6121 gaaaatgttg tcggtgcatc tgcttcttta tcagtttttc cacaagccac taaaatagct
     6181 aacgtgctca ggaccactcc tgctgttaag agccactttt tctatttcat aaaaaatctc
     6241 ctttggttta ttttaatcta cttttacaat ccaaccttct ggcgcttcaa tatcgccaaa
     6301 ctgaataccc gtcaattcat tatataattt acgcgtcaca ggacctactt ctgtttcact
     6361 atagaataca tggaaatcat caccatgttg aatacctcca attggagaaa taaccgctgc
     6421 tgtaccacag gcacctgcct ctacaaaacg gtcaagatta tcaattggaa catcaccctc
     6481 aataggagtt aatcccaagc gatgttctgc caaataaagc aaggaatact tggtaataga
     6541 tggcaagata gatggactca atggtgttac aaattcatta tcagctgtaa ttccaaagaa
     6601 attagctgat ccgacttctt caatctttgt atgagttgat gggtccagat agataacatc
     6661 tgagaaatgg cgtgacttgg ccatttttcc tggtaagaga cttgcagcat agtttccacc
     6721 aaccttagcc gcacctgtac catttggtgc tgcacggtcg tactcatcct gaatcaagaa
     6781 gttggttggg accaaaccac ctttaaagta atttccaact ggcatagcaa agatggtgaa
     6841 aatgtactct tctgccggtt ttaccccgat aatatctccg acaccaatca aaagagggcg
     6901 aagatataag gttccaccta ttccgtatgg tggtacgtat tcttcattcg cacggacaac
     6961 tgctttacaa gcttctacaa acatgtctgt cggaacttgt ggcatcaaga gacggtcaca
     7021 tgtacgttgc aggcgtttag cattttcatc aggacggaac agttgaacac tgccatcctt
     7081 agtacgataa gctttcaaac cttcaaatgc ttgttgtcca tagtgaagac ttggagaaga
     7141 ctctgaaata tgcaaagttg catcctctgt aagctctcct tgatcccatt gtccattttt
     7201 gaaatgagca agatagcgat aaggtaattt catataggaa aaaccgaggt tttcccaatc
     7261 aatcgttact gtcatattcc actccttatt ctaaaaacct atttcttata ttctacacta
     7321 tttttctaaa atagcaagta tattttgtaa ttttcagaaa attcctccaa taaaaaccat
     7381 cttagaactg attcttcatt tcacttattt atcttcagta actacttcct gaagataagc
     7441 gtcaaaaact tcttcatctg aaatcgtgtc agaaatgaag cttccattgc tagtgcgttc
     7501 tgacaagttc aagtcttgca atcggctttc atagattgtt cctttattgg attggacaag
     7561 cagagtttgg tcgttcacat ccacttccgt actgaagaaa tcgccaacaa atccttgctc
     7621 tgcaactgct cctgccaaga agacacgatg cggtttgttt ttcaactcac gcaagacttg
     7681 taatcctcgt ttggcacggc tggttgctag aatttcctca atggaaacac gtttcaagct
     7741 tccacgctgg gtcaagaggt agaaggacga agtattacag ataaagccag attggaggac
     7801 atcatcttct ttcaaattca tagccttgac acctgctgcc ttagcaccga caaccggaac
     7861 ctcttcgata ttgaaacgca gggcataacc attttgacta accaagacaa catcatctag
     7921 tttaatcgga gccactgcta caatctgatc tgtatcgtct ttgagcttag catacttgac
     7981 agacttagat ctataggtcc gccatggagt gaattctttt cgctctaccc gtttgatttg
     8041 accaaggcga gtcgctgcaa agtaggttgt cgcatcgtca aactgatcca gtacttccac
     8101 ataaaggatt gcttcattcg tttcaaagtt tgtgatggtt tggctcagat gctctccgat
     8161 gtccttccaa cgaatatctg ccaactcatg gattggtctg tagatgacat ttccaagact
     8221 tgtgaacatc aagaggtgct gggttgtctt ggcagattga acaaaaatca aacggtcatc
     8281 atcacgcttg ccaatttctt ccaaggtgga agccgcaaag gaacgtggac tggtacgctt
     8341 gatgtaacct gccttggtca cgctgacgta ggtatcttcc tcagcgataa gactagctgt
     8401 atcaatctca attgctttcg cagtgtcttc taaagaactc aaacgaggag ttgcaaagtt
     8461 cttcttgacc tcacgaagtt ctttcttcat gagattgtac atagtccttt catcaccgat
     8521 aatagccgcc agcatagcaa tcttctcacg aagctctgct tcttcttcct gcaagacaac
     8581 cacatcggta ttggtcaaac ggtacagttg caaagttacg atagcctcag cctgttcttc
     8641 cgtaaaatca tagctaactt tgaggttttc cttggcgtcc gccttattct cagaagcacg
     8701 gataagagca atgacttcat ccaaaatcga aatcacacga atcaaacctt cgacgatacg
     8761 gagacgtttc tcagcctttt ctttgtcaaa gcgtgaacgc gccaaaatca cttctcgacg
     8821 gtgagcgatg tagctagaca ggattggaac aatcccaacc tgacgaggtg tgaaattgtc
     8881 aatcgccacc atattaaagt tgtagttgat ttgtaggtcg gtgtacttaa ataagtagtt
     8941 gagaacaagc tcagtattag cgtctttctt aagttcaata gcgatacgaa gaccatcacg
     9001 gtcagactca tcacgaacct cagcaatccc agctaccttg ttattaacac gaacatcatc
     9061 gattttcttg actagattgg ccttattgat ttcataagga atctcagtaa taacgatttg
     9121 ttccttacca ccttttagct tttcaatttc agtcttggaa cgaacaacca cgcgcccttt
     9181 cccagtctca taggctttct tgatttcatc acgaccctga ataatagccc ctgtagggaa
     9241 gtctggtcca ggtaagaatt ccatgagttt atcaatcttt gcagttgggt ggtcaatcat
     9301 gtaaactgca gcatctatga cctcagctaa attatgggga ggaatgtctg tggcataacc
     9361 agccgaaatc ccagtcgaac cattgaccaa gaggtttgga aaggctgctg gcaagaccgt
     9421 tggttctttc tccgtatcgt caaagttcca tgcaaaagga actgtctttt tctcgatatc
     9481 ctgaagaagg tagcctgcaa tttcagacaa acgtgcctca gtataacgca tagccgcagg
     9541 aggatctccg tccatagaac cgttattacc gtgcatttca actagaatct cacgattttt
     9601 ccagttctgt gacatacgaa ccatggcatc atagatagaa gaatccccgt gtgggtggaa
     9661 attccccatg atgttcccga ctgacttggc cgacttacgg tagctcttgt caaaagtatt
     9721 gctatcctta ttcatagaat aaagaatacg gcgttgaacc ggcttcaacc catcacgaat
     9781 atctggcaaa gcccggtctt gaataatgta cttggagtag cgaccaaagc gctctcccat
     9841 gatgtcctcc agggacatgt tttgaatgtt agacataaga tacaaagccc ataaaatacc
     9901 aagtgaaaat agaaaattct tgaagtaagc aaactcacaa gagaatttat ctttttcaca
     9961 cagtatctag ggcgtgttca actcctttca aagaatgtag agtaggtttt tatgcagtaa
    10021 aagatatttt acgggaattc gtcccgtgtt cagttacgat aagtaaccaa actatcctgt
    10081 ttgtattttt caatatgaaa atctggtttt ccaaaattag tcttagtttg tgtcttaacc
    10141 gctcccttaa gcgcctcttt aagataagca ctcatagcag attcttcatt aataatcctg
    10201 caattttttc aaaccaagat tttcaaactg ctttttcaca tagtcattca catccgactc
    10261 taatttccag tttactaaca tattattttc tttcattaaa acactgtcgc ttcttctagc
    10321 gtaaacttga cattatcttc aatccattta cggcgtggtt ctaccttatc tcccatgaga
    10381 acattgacgc ggcgttcggc gcgcgctaaa tcttcaattg tgacacggat gagggtacgt
    10441 gtttctgggt tcatggttgt ttcccagagc tggtccgcat tcatctcacc aagtcctttg
    10501 tatcgttgga gggtagcgcc tttaccgaac tgtttacgga gttcttctag ttctccgtcc
    10561 gtccaagcgt aggccacttc ttctttcttg cctttacctt tggacatctt gtaaagaggt
    10621 gggagggcaa tatagacatg acctgcctcg actagcggac gcatgtaacg gtagaaaaat
    10681 gtcaagagca aggtctggat atgggcaccg tcggtatccg catcggtcat gataatgatc
    10741 ttatcatagt tggcatcttc aatagagaag tctgctccaa cacccgcacc aatggtataa
    10801 atcatggtat tgatctcttc atttttgagg atatccgcca tcttggcctt ggctgtattg
    10861 ataaccttac cacgaagagg tagaatagcc tggaacttgc ggtcacgacc ttgtttggca
    10921 gaaccaccgg cagagtcccc ctcaactaga tagagttcat tcttagcagg attcttagat
    10981 tgggctgggg tcaatttccc agacaacaag cccttatctt tcttgttttt cttcccattt
    11041 cggctctcat cacgcgcctt acgtgctgct tcacgagcat cacgggcctt gatagccttg
    11101 cggatgaggt tagaagctaa ttccccattt tccataagga aaaaggtcaa cttatcagcc
    11161 actattccat ccacaactgg gcgagctagg gggcttccta gtttatcctt ggtctgtcct
    11221 tcaaactgca agtgttcttc aggaactaag atagaaagaa cggccgctag tccctcacga
    11281 tagtctgaac cttcaaggtt tttatctttt tccttgagaa gacctgtttt acgtgcatag
    11341 tcattcatga ccttggtaat ggcagacttg agtcctgtct cgtgcgttcc accgtccttg
    11401 gtgcgaacgt tattgacaaa ggatagaatg ttatctgaga atccgtcatt gtactggagg
    11461 gctacttcca cttgaaaacc attgtcttcc ccttcaaagt aaagaactgg cgtcaagatt
    11521 tccttatctt cgttgagata agaaacaaaa tcttgtactc cattctcata gtggaactca
    11581 atcgcttcat ctgttcgctt gtccgttaaa gacaaggtca catttttcaa gagaaaggct
    11641 gattcattaa ggcgctctga aatggtattg tacttgaaat ctgtcgtaga aaagatagtc
    11701 gcgtcaggca taaaagtaac tttggtgcct gttttagact tgagtgctgt accgattttc
    11761 ttcaaagtcg tgacaggttt tccaccattt tcaaaacgtt gcttgtaaac tgcgccatca
    11821 cgggtaattt caacttctaa ccagctagaa agggcgttaa caacggaaga acccactccg
    11881 tgaagtccac ctgatgtctt atagccacct tgaccgaatt tccctccggc atgaagaatg
    11941 gtaaagataa cctcaacagt tggaattccc atagcgtgca tacctgtcgg catcccacgt
    12001 ccatggtctt gaaccgttag actaccgtct ttattgatag ttacatcaat acgatcacca
    12061 aacccagaca aggcttcatc gactgcatta tcaacgattt cccaaactag gtgatgaaga
    12121 ccagcgccat cggtcgatcc aatatacatc cctggacgtt ttcggaccgc atccaaccct
    12181 tctagcacct gaatagcatc atcattataa ttgttaatat tgatttcctt ttttgacaca
    12241 aggaacctcc tattcgttca tctttactat tctacaggtt ttccaaggat tttgcaaaat
    12301 ttttctttct ccgatgtgac aatttcagca gagattctct gcttttcttt cccaattcat
    12361 gatataatag gagtatgatt acaatagttt tattaatcct agcctatctg ctgggttcga
    12421 ttccatctgg tctctggatt ggacaagtat tctttcaaat caatctacgc gagcatggtt
    12481 ctggtaacac tggaacgacc aacaccttcc gcattttagg taagaaagct ggtatggcaa
    12541 cctttgtgat tgactttttc aaaggaaccc tagcaacgct gcttccgatt atttttcatc
    12601 tacaaggcgt ttctcctctc atctttggac ttttggctgt tatcggccat accttcccta
    12661 tctttgcagg atttaaaggt ggtaaggctg tcgcaaccag tgctggagtg attttcggat
    12721 ttgcgcctat cttctgtctc taccttgcga ttatcttctt tggagctctc tatcttggca
    12781 gtatgatttc actgtctagt gtcacagcat cgatcgcggc tgttatcggg gttctgctct
    12841 ttccactttt tggttttatc ctgagtaact atgactctct cttcatcgct attatcttag
    12901 cacttgctag tttgattatc attcgtcata aggacaatat agctcgtatc aaaaataaaa
    12961 ctgaaaattt ggtcccttgg ggattgaacc taacccatca agatcctaaa aaataaaacg
    13021 ccagttctgt actgccccca aacagttaga caaataattt atccaaagga tttagttctg
    13081 tattgcacag gg
//
LOCUS       DAVKMJ010000047        12544 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000047 DAVKMJ010000000
VERSION     DAVKMJ010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12544
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.047"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            131..295
                     /locus_tag="VW348_001730"
     CDS             131..295
                     /locus_tag="VW348_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEU9746596.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            379..945
                     /gene="amaP"
                     /locus_tag="VW348_001731"
     CDS             379..945
                     /gene="amaP"
                     /locus_tag="VW348_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEU9746597.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            957..1127
                     /locus_tag="VW348_001732"
     CDS             957..1127
                     /locus_tag="VW348_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEU9746598.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1166..1774
                     /locus_tag="VW348_001733"
     CDS             1166..1774
                     /locus_tag="VW348_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU9746599.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1805..2008
                     /locus_tag="VW348_001734"
     CDS             1805..2008
                     /locus_tag="VW348_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEU9746600.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2103..2381)
                     /locus_tag="VW348_001735"
                     /pseudo
     CDS             complement(2103..2381)
                     /locus_tag="VW348_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2579..2866
                     /locus_tag="VW348_001736"
     CDS             2579..2866
                     /locus_tag="VW348_001736"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEU9746601.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCPRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(3144..3914)
                     /locus_tag="VW348_001737"
     CDS             complement(3144..3914)
                     /locus_tag="VW348_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEU9746602.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3929..4777)
                     /locus_tag="VW348_001738"
     CDS             complement(3929..4777)
                     /locus_tag="VW348_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HEU9746603.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDGFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(4774..6249)
                     /locus_tag="VW348_001739"
     CDS             complement(4774..6249)
                     /locus_tag="VW348_001739"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEU9746604.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6572..7927)
                     /locus_tag="VW348_001740"
     CDS             complement(6572..7927)
                     /locus_tag="VW348_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9746605.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(7937..8254)
                     /locus_tag="VW348_001741"
     CDS             complement(7937..8254)
                     /locus_tag="VW348_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9746606.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEKTSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8271..8588)
                     /locus_tag="VW348_001742"
     CDS             complement(8271..8588)
                     /locus_tag="VW348_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9746607.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8601..10286)
                     /locus_tag="VW348_001743"
     CDS             complement(8601..10286)
                     /locus_tag="VW348_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HEU9746608.1"
                     /translation="MKNKKLILSLFILFLLIFIHAKVFANENLIKNSNFEQGELFWNS
                     RNRGIINSNESYSNGHYSGMIPSTAINDNRADGYIGQVIDIEPNEDYLVSAFAKVDIS
                     GAEGYFTARWFDNNKQGEIVQNNIGEAVDQTVNTTEWKKYMFSFNSGKHDKVLIQLVK
                     WSEDDTTKKSNIFIDNVEMYQLSKGNSYKKIWRDDFDGEQLNKKYWGYELGSIRGWEQ
                     QHYVRSDENVFLRSGNLVLRATNRSKEDQYFNPRNNHRKVVYNSGSVRTHGKVEFLYG
                     KLEMRAKLPKGQGVFPAFWTLGSDFTLDGKINPVQGRGWPSTGEIDIMELVGERNSNG
                     SGNKTVYQTLHYGQSDNDDGKFAGRGTAFKLSSGNFNDSYHTFSIDWYKDYIVWMVDN
                     HIVRKVYYGSDNIAKKIFNRPQYVQLNLAMGGSWPGVVDNNLSGTEFVVDYVSYSRND
                     LQQHQAEEYYSQSPKINGAKDIVINRGDVPDLLKGITTNSGYELDYSIENEPMFNNFG
                     GNTSVDLLIRNKTEKEKISQMPPGVYNLHYTSRPKHLDYESKVDRKTVTLTIK"
     gene            complement(10291..11187)
                     /locus_tag="VW348_001744"
     CDS             complement(10291..11187)
                     /locus_tag="VW348_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEU9746609.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNQEIIKAVQSAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(11190..12452)
                     /locus_tag="VW348_001745"
     CDS             complement(11190..12452)
                     /locus_tag="VW348_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEU9746610.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
BASE COUNT         4267 a         2531 c         1860 g         3886 t
ORIGIN      
        1 aatagtatta atcaaagaaa ttgatttttt gatattaaaa taaaaaagga gggtaggcag
       61 tgttgtgatc aattattgct ggaggtctta ttggtctctt ggcaggtaaa atcactaaaa
      121 aagtagttct atgggaatca tcgcaaatgt attcgctggt ttagtcgggg catatgcagg
      181 acaatctctt ttaggtagtt ggggtccatc aatcgctgga atggctttgc tcccatctat
      241 tgtaggtgca gcgattgtga ttactgtagt gtcattcttt acaggtagaa agtaaacttt
      301 tcgccagtaa agttagcaaa ctatttttaa atcaatgacg ggaaaaatag tttaaatgtt
      361 aaatcgaaag gattgtatat gtcaaaagca aagaaaatat gtttcattat tttctgtatt
      421 ttaatcttga caattttcct tcctgttttg atagattatc atcaagttag tgatctaggt
      481 attcatctac ttagctggag acagaactcc gtagttgaat tctatcttgc tagatatgtc
      541 ttttggggga cagtggttct atcaacttta gttttattat ccattttagt tgtgatgttt
      601 tatcctaaac gttacttgga aatccaactt gaaactaaaa acgatacatt aaaattaaag
      661 aattcggcaa tcgaaggttt tgttagaagt ttggtgagtg atcatagatt gatcaagaac
      721 ccaactgttc atgtaaattt acgaaaaaat aaatgtttcg ttcatgtaga aggtaaaatt
      781 cttccttcag acaacatcgc tgacagatgc caaataattc aaaatgaaat aactaatgga
      841 ttgaagcagt tttttggtat tgagcgtcaa gtaaaacttg aagttgcagt aaaaaattac
      901 caaccaaaac ctcaaaacaa aaagactgtt agtcgtgtga agtaaggaag taaaaaatgg
      961 aatggcttaa acaatatcga tatccaatta tcgctggtct cataggcgta tttctggctt
     1021 gtttgattgt ctcctttggc ttcttcaaaa caatatttgt attgatttta ggagcactgg
     1081 gagttgcagc tggattatat atcgaaaaaa actatataga taaataaaaa aataaaaatt
     1141 actaatttaa ttaaaggagt ttcatatgtc aaacgaaaaa aacacaaaca ctaacgtaga
     1201 aaagaaagat gctactgttg tagctcacga aatcaaaggg gaacttactt acgaagataa
     1261 agttatccaa aaaatcattg gtctttcact agaaaacgtt tcaggtcttt tgggaatcga
     1321 tggtggtttc ttctcaaatc ttaaagaaaa aatcgttaac agcgatgacg taacaagtgg
     1381 tgttaacgta gaagttggta aaacacaagt tgcagttgac ttaaacgtta ttgttgagta
     1441 ccaaaaaaat gttccagctt tatattcaga aatcagagaa atcgtatctt cagaagttgc
     1501 taaaatgact gacttggaaa ttgttgaaat caacgtaaac gttgtcgaca tcaaaactaa
     1561 agaacagcat gaagcagact cagtaagcct tcaagatcgc gtatctgacg ttgctgaatc
     1621 aacaggagaa ttcacttcag aacaattcga aaaagctaaa tctggtcttg gatctggttt
     1681 ctcaactgtt caagaaaaag ttagcgaagg tgtagaagct gttaaaggtg cagcaaatgg
     1741 tgtagtatct cacgaaaaca ctcgtgtaaa ctaagataaa ataaatataa caggagaaat
     1801 tatcatgtca gtagaagaaa aattaaatca agctaaaggt tctattaaag aaggtgttgg
     1861 gaaagccatc ggtgatgaaa aaatggaaaa agaaggagca gctgaaaaag ttgtttctaa
     1921 agtaaaagaa gttgccgaag acgctaaaga cgctgtagaa ggtgctgtag aaggtgttaa
     1981 aaacatgttg agtggcgacg ataaataagg ttaaaagtta ctttatcttt ttggtaacat
     2041 tagtcaagat gattctcaga aaacaaaaag ctagagattc ccaattgcgg aaccctagct
     2101 ttttaatttt gcctctttct cttattatat ttcagcaggt tgttggccat gagtacgaat
     2161 cccatgtcaa ttctcacttg acgcttccct ctcagatgac atctcttata acccaaacaa
     2221 acctttatct gcccaaagac agatttcata tcaatcttac gtttagcgaa aatttgtcta
     2281 cccttggaag ataaaagtgc ctgatattct ttagttttta aacactggta acgttcattc
     2341 atatacagtc ccttttgagg ggctgattca ggttcataat cgcagtcaac attgatttca
     2401 aggctgtttg ctttctatct cccctttttc atgatatatt ttcgtacagg tgcttcaata
     2461 gtttctatag taaaatgaac caaaaatagt acacgttgcg gtataatgtt cttgtggcat
     2521 attcattaga ttttcgtaaa aagttctctc ctatttgtga gcgaacaggt atagtcaatt
     2581 gattgtcagt ttgaagacca agagtcgtaa ggcaaaggat atggcagaat ccatccaagg
     2641 gtggctggca caatttctag tgaacctctt taaatctatt acgtttgact gtggaaaaga
     2701 gttttcaaaa tggaaagata tttccaatca tcacgatagt gagagctttt ttgcgaatct
     2761 aggatgtcca agacagcggt gtctcaacga acattcaaat agacttttaa ggtgtcatga
     2821 cttgccaaag cagacagatt tcaacgaagt cagtcaagaa ttttaggctg ggtaaaaact
     2881 caatttcagg agaaaatgaa ataaatattc ccacaataaa atgcatagta tcaaagtttt
     2941 tccaacacct gatattatgc attttttaat tttaaagact ttttcccagc ctcaagaaat
     3001 cacatcccac ctaaatcctt tggataccaa atacctcatc aggtattttc tgagttggta
     3061 agactgtcta gcttaatttg acaaatggag ggcgttaaat ccagttttta caggaagtct
     3121 atttaaatat tttcacactg accttacaaa atatgaaaca aattatataa agtcattccc
     3181 atgacaaaga ataacatccc tttaaaacag tatcttaccc aattttcagg taagactttt
     3241 gatacaaccg tccccaatac ccctccgcat atagaagcaa gaaaaataac tggaacaggt
     3301 gctaaatgat actgatttaa acctgtaacc acaacaattg tagccaaatg agacagctgg
     3361 gaaaagaaaa taattgcaag agaatacatc gttgcttctt ttatcgaaat agaaaaaaac
     3421 accatcaata aagatacatt gagcggacca ccaccaatcc ctaaaaaact agaaattaag
     3481 cccaatagaa gaccacaaat catatagaat cctatcttat caaattgata agttttttta
     3541 aaatctgtta aaacaaatga tacaagtagc atcacaaata gtaaaatcat ttgaacaatg
     3601 gatactagcc gtactgataa ttgagataac aaaacttgaa aaataagatg acctagaaat
     3661 cctcctaaaa cagaagaaaa ggataccgta aaaatcaatc tccattttat ctctttactt
     3721 tgtgaaaatc ttttgattgt tgaaataatc gccattataa aaacagagaa actagaataa
     3781 aaagcaatat cactgaccga atggtatcca aaactatcca taagtggctt aattataatt
     3841 ccaccaccca tgcctgatat agaacccaat ccactagcta ttataatgat tagaaaataa
     3901 ataatctcaa ccacttttta agtccatcct attctttcaa acatctaaaa cctagatggc
     3961 tactagtgga agtagaaata catccatttc tagcagctac tcggtatcga ttacaataag
     4021 aacaatgaca taaaaaggaa cctcctctga tagcatactc ctcatcttgt atcccatatt
     4081 ttggcaactc atagtcatct tcattaaaac tagctaataa ggtatatctc ggattgcgac
     4141 accattccca aacattccca atcatttgat atagaccaaa atcattaggt aaaaattcat
     4201 agacaggagc cgttcctata aatccatcta aggcagtatt ttcataagga aatcttcctt
     4261 gccaagtatt ggcatgataa tatccacctt ctaaaagagt atctccccaa ggatattcag
     4321 attgtcttcc tcctctagca gcatattccc actgtgcttc agtcggtaaa gacattccgc
     4381 tccaattaca gaaagccaat gcatcttcta aagcaacatg aactactgga tggtcttcta
     4441 aacccactag attactattc tcaccgtagg gatgtttcca gcaagcgttc ggaacttgta
     4501 accaccacgg agccccagca ggatgaggat atccctccct ttctgcctct ggaacgaaca
     4561 atataaaaac aaaagaccac tcttgtcgct cagctagtgt tttatagcct gtttctttca
     4621 caaattgagc aaattcttga ttcgtaactg gagtatccgc aatggaaaaa tcctttacac
     4681 taacagcgac ttgaggacct tcaaaatcat ctaaaaagcc ctcttcagaa tttgttccca
     4741 tcataaatgt cccacccttg atttttttca ttttcatgat tgactatccc ccgttttcgt
     4801 tagagttggc gttattttag aaagttcaac aggaactaac tcttcatcca caacaaaacc
     4861 ttcttctcta tatctaagaa agtctactaa ttttttcttc atctgacgaa caataggttg
     4921 atatttttca cttggataca aatcattcat ttcatgcgga tcttttttca tatcaaataa
     4981 ctgataatga tttaaaacag gaaaccagat aaatttccac tggtctgtca aaatatattg
     5041 actagaatct tttcctaaag catgttcacc atgaaattct gttcgccacc cctcgtactg
     5101 tccaaataat aaattcttaa cactccgtcc atctagttca tctgtagtag ttcctcctgc
     5161 caaatccacg agtgaaggaa aaatatcttg aattttcact aattgcttga ttgttcccct
     5221 attaccagct atcaatccag ccggatcgta aataaacgaa ggaatgtgga tacttccctg
     5281 ataaggatat ccctttctaa acagataatg ttcaccaagc tgatctccat gatccgaaac
     5341 aaaccagata atcgtatctt tatcatgacg aaattctttt agggcagtca aaaagcgact
     5401 aatttgatgg tctatatgag taatcaatcc aaaataagca gcaaccattc ttctttgatc
     5461 atcttccttt aatttccctc ttaaagcata aatagacgga atttgctttt ctaatacttc
     5521 ccaattcccg atatgcaaat cgagaaattg aggcaagcgt tccatataca tatcaaaata
     5581 gtattttggg ggatttaatg gagcatgtgg tttttcaaaa gacattttga gaaaaaaagg
     5641 aaccgttgga tctcttcttt gtaaaaatga aatggactca ctcacaaccc agtttgttgg
     5701 atgtaacttc tcatctttat cccaaggtct agcttcccaa gaattacaat ccattccgtc
     5761 atcaatcaaa tcaacatcat aaccaacttt accctttaaa aaggctagat agtcactagc
     5821 ataatcaaat tgacttccat aagccttatc atactttcta tcaacatgta gatacccatc
     5881 gtgaagtaag acatgatcaa acccaagtct ctgtctggaa ggaaaaacat gcatcttacc
     5941 aatacactct gtttgataac ccatatcttt aaagactttt ggaagagtat tagtaaaatt
     6001 ccaaggcacc tcatcttgat aaccaactcg tccactttta tcttggtcta agccagtcaa
     6061 taaagctgcc ctagcaggaa cgcaagaagg aactggagaa taggcatttt caaaattata
     6121 acctacacta gccatcatat ctaatgttgg agtgctaact agcttatcct tactattcaa
     6181 ggataaggcg tctgctctca tttgatctac aacaatcaaa ataatatttg gctgttttgt
     6241 ctgaaccata aaatctcctt tctaatatgg caaaagaggc acaagaagat atctaccttt
     6301 actgcacccc tttctatatc aatctctcta tataaaacaa taacattctt gttatgtttt
     6361 atagaaaaat gaactaaaat atgactaaat cgattaggaa attcaaatca ttttctagta
     6421 ctgttttaga agttacagtg tactattcca acttcaataa actataaacc tttgtctaat
     6481 aacaatttta gtggagataa gaaatcctac acctaactca tcttacacgt aatctatttc
     6541 tattttatca caaaaaacgc aagtaagacc attaactcaa ttcagtttta tctgccattt
     6601 tcacaaatgg gaaataagtc aagacactaa taatcaaaca aacaactgat aagatgatgg
     6661 cacgccaatc aaatgctgta gagaagaaac catataaaat tggaggcatt acccaagtaa
     6721 cgttttgtgt aacaggtgaa acaagacccc agcttgttgc ccagtaagct accgttgcca
     6781 tgaaaaccgg gctaagtaca aatggtataa atagcaaagg attcaagaca actggtaaac
     6841 cataattgac cggctcacca atattaaaca gaactggtgc tagaccaagt ttagcaactt
     6901 ttcgataatg actgtttctt gaaaaaatta aaatagcaag tactaatcct aatcctccaa
     6961 accagacaaa cgccccaaaa gacccacttg tccatatata aggaatcggt tcaccttttt
     7021 ggaaagcatc cagattcgct aacatagcaa ctccaaacag cccttccatg atgggagcca
     7081 atacatttcc tccatggaga ccaaaaaacc agaataactt attcaaaaag atcatcagaa
     7141 taactgcaaa gaaactttga gacaaaccta gtaatggcgt ttgtaacacc ttgtaaaccc
     7201 aatcaatcaa taagtcattg ctaagtaaat ggaaaacata agtcaagatg gctactatat
     7261 acatcgccat aaatcctgga atgatagaag tgaacggctt agcaatcgca gggggaactg
     7321 aatctggtaa cttgattacc cagttctttt tcattacttt acagaaaata atagaggcta
     7381 aaaatccaat catcatggct gtaaagtagc ctctggcatt aatatggttt cctggaatca
     7441 cattcccaat agttaccatc agatttttac catcaaatgc tagattatca attccttgta
     7501 agatttgatc taatttcaca tctcctacat ttgccaaagg gaaactcttt gtaactgtac
     7561 ttccaatcga aatgacaaac gaagcaagtg ataccaaacc agcagaaact gtatcaacct
     7621 tgtaaatctt agcgatattc actcccaagc aatagatgaa caacaaggaa acaattggta
     7681 tacttccctt gaataccaaa ttattgatgt caacaagcca ctgaaaggtt ttcgtaatac
     7741 tttctaggtg aaattgttgt ggtaaatcca ctagaaaagc atttaataac aaagcaatgg
     7801 aacctgtcat aataacaggc atagtcccca caaatgaatc acgtaaagca actaaaaact
     7861 tctgattccc aactttcatt gcaattggag aaagtttttc ttgcatttta tccaacattg
     7921 tattcatacc aaactcctaa tttttttcaa atcgttcgta tacttctacc acttctttcg
     7981 ccaagtcaac aaaagtcaga ctcgtcatta aatgatcttg cgcgtgtacc atcaagaggc
     8041 taattgatgt tttttccccc tgtgcctctc ttgtcaacat ttctgtttga gccttatgcg
     8101 cctgtaataa ggcagcattc gcatcagcta atcttcgatt ggctttagag aaatcccctt
     8161 tttttgctgc ctgaatagcc tccatagcat tacttttggc ttccccacca tacataatta
     8221 gccccattac agattctaaa ttactttcat ccataacatt ctcctcaatc ttagtctaat
     8281 aaactttcag ctaaatctaa aactttagaa ccattcatca ttccgtaatc tgtcatcgga
     8341 ataaccgcca caggaatctg tctatctttt agtttttctt gaaagtcccc tagtaaatag
     8401 cgaacttgag gacctaaaag caacacattt acttcttttg ttgctacaat ttcttctgct
     8461 tcaggagctg gaactgcaaa aatttctgca tccaacccct tatcttctgc tgccttttgc
     8521 atctttgtca ctagcagact tgtactcata cctgctgcac atgctaacat aattgttact
     8581 ttagccatag cttactcctt ttattttatt gtcaatgtta ctgtttttcg atcaacttta
     8641 gactcataat ctaaatgttt gggacgacta gtataatgca aattataaac tcctggaggc
     8701 atttgtgaaa tcttttcttt ttcagtttta ttgcgaatta ataaatctac cgaagtattc
     8761 cctccaaagt tattaaacat aggttcattt tcaatagaat aatctaactc atatccacta
     8821 ttagttgtaa ttccttttaa taaatcagga acatctcctc tgtttattac tatatcctta
     8881 gcgccattta ttttgggaga ttgactataa tactcttcag cttgatgttg ttgtaaatca
     8941 tttctagagt aagaaacata atcaactaca aattcagtcc ctgataaatt attgtccact
     9001 accccaggcc aacttcctcc catcgctaaa tttaactgaa catactgagg tctattaaaa
     9061 atctttttcg ctatattatc tgatccataa tatacttttc taacaatatg attgtcaacc
     9121 atccatacaa tataatcttt ataccaatca attgaaaaag tatgatacga atcattaaag
     9181 tttccactcg ataatttaaa ggctgtacca cgtcctgcaa attttccatc atcattatcc
     9241 gactgtccat aatgaagcgt ttgataaact gtcttattcc cacttccatt tgaatttcgt
     9301 tcaccaacta attccattat atctatctca cctgttgacg gccatcctcg tccctgaaca
     9361 ggattaatct tcccatcaag tgtaaaatcc gatccaagag tccagaaagc aggaaaaact
     9421 ccttgacctt tcggtaattt tgcacgcatc tctaatttac cataaagaaa ttctactttc
     9481 ccatgtgttc taacacttcc tgaattatat acaacctttc tgtgattgtt tcttgggtta
     9541 aaatactgat cttccttaga gcgattcgta gctctaagaa ctaaatttcc cgaacgtaga
     9601 aaaacattct catcacttct tacataatgt tgctgttccc aaccacgaat tgatcctaat
     9661 tcatatcccc aatatttttt atttaattgt tcgccatcaa aatcatctct ccaaattttc
     9721 ttatatgaat ttcctttaga cagttgatac atctctacat tatcaataaa aatattagat
     9781 ttttttgtag tatcgtcttc tgaccatttc actaattgaa tcaaaacttt atcgtgttta
     9841 ccggaattga aagaaaacat gtattttttc cattcggttg tattaactgt ttgatcaaca
     9901 gcttctccaa tgttattttg aacaatctct ccttgcttat tattatcaaa ccatcttgcg
     9961 gtaaaatatc cctctgctcc actaatatct actttggcaa aagcagatac taaataatct
    10021 tcattaggtt ctatatcaat aacttgtcca atatatccat ctgctctatt atcattaatt
    10081 gcagtagaag gaatcatacc tgagtaatgt ccgttactat aactctcatt tgaattaatt
    10141 attcccctat ttctagagtt ccaaaacagc tctccttgct caaaatttga attttttatt
    10201 aaattttcat tagcaaaaac tttcgcatga ataaatatta ataaaaataa tataaataaa
    10261 cttaaaatta atttcttatt cttcatttta tcacctattt actgacctag ccaagcgaga
    10321 tactgtatgt ctcactcctc taattgcctt gctcaatgca taaatattat cgactgttgc
    10381 cagtccccca tatcctgcgt cacctatatg ttgaatatca actccacaaa ttttatttct
    10441 aagtgcaatt tccttgatag tatctgtatc agatgtttct tggctagtac caatagcact
    10501 caatacaaga ccacccttac tatgaacgag atcaacgact tcacgcaact cttggtcatg
    10561 aaaggctgga acggttccaa ctgctggaac aagtatcaca tccgcacctg cttccaacaa
    10621 ttgctctgcg acagaaagct ctgccacagg ctcattcact cctgccccgt gcattttacc
    10681 agctataatc aaacctgaga aattctcttt agcagattga actgctttga taatctcttg
    10741 attgctaact cctgttccag gatttccagt caaacagaca aagtcaaaac ctaactcctc
    10801 tattcgattc aatgtttcaa cactagcaac acgacctgca acaatttcct gtgtttcctc
    10861 tagcatcttt gcagatgggt caatcggttc caaatttaca ccaattggac aagcaacaag
    10921 ctggtgtaag cgatgaataa catcatcacc tgaactatcc aaagcataaa ttttaggctc
    10981 aaaaacatca acacaattca ataaaatcat atcagctcca aaagctctag caatttcaga
    11041 attagttata tccccaacaa atgtctcacg agtaactaca ttttcagata gaacaactct
    11101 accttcactt gctaaaatac tttgttttaa ttcttcagca ttcatctgta atatctcaga
    11161 tggatttgca ctaattaaac gtttcattct caatcctcca ataacttaaa ccgtttttca
    11221 atagctatta caaatggtaa ataaagtaag acatccaaaa caatcaatac aatttgtaat
    11281 aatgaaccag aaatacttcc tgtagcaagt aaaccactta taacaggtgg catagtccaa
    11341 cctggatctg tataagttag cggaaccaaa cctgatgcca ttgctcccca cgctactagt
    11401 aagttaaaca ttggagctaa gataaatgga actagtaaca aaatgttcaa aacaatagga
    11461 acgccaaaca ttgctggttc atttatatta aataatccag gtataacagt tataggtgcc
    11521 aaagttttta gttgtttact agctttcttc ttatgtgcta aatatcctaa cgcaagaact
    11581 aaacctatgg ttgcaccacc gccacctatg aatacaaaat tatccataaa tacgctagta
    11641 aaaatatttg gaagagtttc tccagtttga taagctactt tatttgcatc tagattagct
    11701 aaccataacg gtttcataac tgcattaaca acatttcctc cgtgtaatcc tacaaaccaa
    11761 aaactactat taaggaaaat taagataaga agaccaataa cattatttcc taaaagtcca
    11821 agtggacctc ccaaagctac ttgagcaatt tcatgaagat taggtaaact taatttatct
    11881 aaagttgcat aaacaatcaa ccaaccaaca atagtcactg caccaggaat aatggcacta
    11941 aagcttttag atactgctgg tggaacacca tccggcattt ttatctgtat attatgattt
    12001 ataaaccatt ggtagatata gccattaatc aatcctaaaa tcatagcaac aaataaacct
    12061 tttgatgcca tgaaagcggt aggcattcct gctccagcct ctcctctaat gaaaggcgta
    12121 actgtaataa aagatgataa tgacacaata ccagcaggaa taccatcaac tttgtattgt
    12181 ctagccataa agtaagcgat accaaaacta gctacaagac caagtaatcc aaaactacta
    12241 tcaacaccct tccataaata gtcagcaaca ccaatatcac ccagatattt ttcccatcct
    12301 ggaataggaa aacttgcaat aaccattagt aatgaaccta tcaacaataa aggtatagtt
    12361 agagtaatac cgtctcgaat agaaaccaac gctttattat tacccaatct agccgctact
    12421 ggaagtaact tttcttgtaa taatttttcc ataacctttt cctcttaaat atattttatt
    12481 atcaaaagtt atcaattatc tttatttttt gacgtcaagt tgttatttga ttatcttttg
    12541 ttat
//
LOCUS       DAVKMJ010000048        12387 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000048 DAVKMJ010000000
VERSION     DAVKMJ010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12387
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.048"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(344..544)
                     /locus_tag="VW348_001746"
     CDS             complement(344..544)
                     /locus_tag="VW348_001746"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746611.1"
                     /translation="MESVLESLKQEKDHLEKIIKVVTSGGKFLRLPYQKKSRSISENL
                     KLISQNLDKLSEQVQQTTNQHS"
     gene            complement(576..791)
                     /locus_tag="VW348_001747"
     CDS             complement(576..791)
                     /locus_tag="VW348_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001198773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9746612.1"
                     /translation="MQWTLEAMRINKGLTQAELAEKFEVSSQTIARLEKDSSDIGYQL
                     LKKYMFFFNVKFDDIFLGKKYENFVNN"
     gene            complement(810..974)
                     /locus_tag="VW348_001748"
     CDS             complement(810..974)
                     /locus_tag="VW348_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746613.1"
                     /translation="MKENIEHLHERIKHFQSLIAYMSEHEKKYYLEKDWFDNPTLISI
                     EDAKKEVELL"
     gene            1181..1870
                     /locus_tag="VW348_001749"
     CDS             1181..1870
                     /locus_tag="VW348_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HEU9746614.1"
                     /translation="MIFRVKVNSSVSRPVTVEDICPNCKKPTNPDLVNSSYFSLGENK
                     TSLVLTCRCLGCKHFWTEEFIATRFLINDYTEKYEIEHIKVIPNLPSDIPISDDVEIV
                     SPIGKQIYVQALKAEHEQLDHIAGIGYRKALEFFVKDFSIVTNPDDEDKIIKMSLKQV
                     IEKYIKDEDLKTFALASAYIGNDEGHYYRNNPDKGFTDLKNYLHGVIHYMEMKLNFLD
                     AQELVNRSKKS"
     gene            2114..2905
                     /locus_tag="VW348_001750"
     CDS             2114..2905
                     /locus_tag="VW348_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9746615.1"
                     /translation="MDEKKRMQIIAENITHFRKQRGITQKELAKEVGITASTMTDYMK
                     LRSAPSFGVIQKLADYFGVKKSDIDTTFKEESTNSLPDAPDSLTQQIMDKVVQLTPPN
                     QKIVLRTSEELLESQNEEETKINEVSEVISLYQVEVVSETAAASGFNYGFGYDDTDRE
                     TIEVDERPPRHDIATKVSGDSMQPDYQDGDILYLVDKGLTTYNGDLAIIAYGDRSYFK
                     KIYTENGRLRLVSLNDKYEDIILDFPPAEDTHIKIYAVVGVYRGE"
     gene            3054..4004
                     /locus_tag="VW348_001751"
     CDS             3054..4004
                     /locus_tag="VW348_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HEU9746616.1"
                     /translation="MKPFKTIEEQIATLKIRGLSITDESKAAKYLLSNNYYNIINGYS
                     KFFQHPGTDTYIDGVTFDEVSSLYTFDKDVKRAILQAILEAEHHIKSITAHRFAEAYP
                     SQKYAYLNTNSYADNKILDVGFIVSKLSKIINTNKRYRGNSIHHYAHTHSDVPIWVLT
                     DYLEFGDLRTIIENLPNSLQNEIARDLVSFISTNIPDFNDVFPPETLISFLKNINEVR
                     NKCAHNNRLLNFRCRSNSTFWETIHNKEILMGDDSRKTVYSTIISLQCFISKAAFNIL
                     WNTLRKKVIKLEKKLPSIDINVINQSLGFPNDWHRNEPKV"
     gene            4283..5410
                     /locus_tag="VW348_001752"
     CDS             4283..5410
                     /locus_tag="VW348_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEU9746617.1"
                     /translation="MWMEELPNGKFKYFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKINKKLSTKQVESITFEEIYNLFYKSWAQTVKESTKHNCKSVDKKMKEVIPSD
                     TILANLDRRFLQEAIEKIIESNGYITAKKVRHRLRGIFNYAVQYSYIENNEVDYTTIP
                     QKPKTLEELEKKRNNFLTMQEIKALVDVLNRREYHQKYADMVLVLTLTGMRYGELTAL
                     QLKNIDFENNKIEITGNFDSVNKIKTLPKTTNSIRTIKVSESVIEAIQRQIVRLSERF
                     QPLSSDDYIFCFEKWNQPTTIACFIQILKKYGKQAKIEKNLSSHIFRHSHISFLAESD
                     LPIKSIMDRVGHSNAKMTLEIYSHTTEDMEDKLVNKLDTIF"
     gene            complement(5498..6409)
                     /gene="whiA"
                     /locus_tag="VW348_001753"
     CDS             complement(5498..6409)
                     /gene="whiA"
                     /locus_tag="VW348_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEU9746618.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(6406..7383)
                     /locus_tag="VW348_001754"
     CDS             complement(6406..7383)
                     /locus_tag="VW348_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEU9746619.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            complement(7380..8270)
                     /gene="rapZ"
                     /locus_tag="VW348_001755"
     CDS             complement(7380..8270)
                     /gene="rapZ"
                     /locus_tag="VW348_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEU9746620.1"
                     /translation="MTKKQFHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            complement(8322..8702)
                     /locus_tag="VW348_001756"
     CDS             complement(8322..8702)
                     /locus_tag="VW348_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEU9746621.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            complement(8713..9300)
                     /locus_tag="VW348_001757"
     CDS             complement(8713..9300)
                     /locus_tag="VW348_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEU9746622.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            complement(9309..10541)
                     /gene="clpX"
                     /locus_tag="VW348_001758"
     CDS             complement(9309..10541)
                     /gene="clpX"
                     /locus_tag="VW348_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEU9746623.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            complement(10573..10743)
                     /locus_tag="VW348_001759"
     CDS             complement(10573..10743)
                     /locus_tag="VW348_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746624.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            complement(10743..11249)
                     /locus_tag="VW348_001760"
     CDS             complement(10743..11249)
                     /locus_tag="VW348_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEU9746625.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQDQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            complement(11379..11897)
                     /locus_tag="VW348_001761"
     CDS             complement(11379..11897)
                     /locus_tag="VW348_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEU9746626.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
BASE COUNT         3865 a         2627 c         2214 g         3681 t
ORIGIN      
        1 ctcaagaaaa ctagtgtttc ttaaaagttt ttcaactaac tcagggtctg cctttacaaa
       61 ggtggactct tttttcccac tatacggata tcgtcttggt ctcatttcct cacctccttt
      121 gtatttattt tttctaccct ctcttttatt tagagaagta ggactggttg tcttttaata
      181 cttgttgtta gttaatattt attagtgtaa aaaatttgac atgaaaaagt ttgacatgaa
      241 aaaaacttac atctcaaaaa tttaatcact aatcgcttta tcgagtcgct gtaacatgat
      301 atcaaactgg aaatcaaaac aggtttcttt cgtcatcttg aaatcatgaa tgctgattcg
      361 tggtttgttg aacttgctcg ctcaatttat caagattttg agaaatcaat ttcagattct
      421 cactaatcga gcgtgacttt ttttgatacg gcaatctcag aaatttacca ccagaggtaa
      481 ctaccttaat gattttttcg aggtggtctt tttcttgttt caagctttca agaacgcttt
      541 ccatctatgt gttcctcctt cttatttttt tgtttctagt tatttacgaa attttcgtat
      601 tttttcccta aaaaaatatc atcgaatttc acattgaaaa aaaacatgta ttttttcaat
      661 agctgataac cgatatcaga gctatctttt tctaatctag caattgtttg acttgaaact
      721 tcaaattttt ctgccaactc tgcttgagta agtcctttgt tgattctcat agcttctaaa
      781 gtccactgca cgttcctacc tcctttctgt taaagtagtt ctacttcttt ttttgcgtct
      841 tctatagaaa ttagggttgg gttatcgaac caatcttttt ctaaataata ctttttctca
      901 tgctcagaca tataagcaat caatgactga aaatgcttta tgcgttcatg aagatgttct
      961 atattttctt tcatccatcc tcctactcct taaatttttc caaatatatt tttcgcttgt
     1021 atatttccaa catcaatctt attgatattc aacattaact cagggtctgc ctttacgaag
     1081 gtggactctt ttttcccact atacggatat cgtcttggtc tcatttcctc accccctttc
     1141 aaatatggta taatcaaaat aaaacgattg gagaaatctt atgatatttc gagtgaaagt
     1201 aaattcttct gtttctaggc ctgtaaccgt tgaagacatt tgcccaaatt gtaaaaaacc
     1261 aaccaatcca gatcttgtga actcttctta tttttctctt ggagaaaata aaacaagctt
     1321 agtattaaca tgtagatgct taggttgtaa gcacttttgg acagaggagt ttatagctac
     1381 aagattttta atcaatgact ataccgaaaa atacgaaatt gaacatatca aagtaatccc
     1441 taatcttccg agcgatatac ctatatctga cgatgtagag atagtttctc caattggtaa
     1501 gcaaatctat gtccaagcac tgaaagctga acacgaacaa ctagaccaca ttgcaggtat
     1561 tggataccgt aaggcgcttg agttctttgt taaagatttc tccattgtta caaatcctga
     1621 tgatgaagat aaaatcatta aaatgtcatt aaaacaagtt attgaaaaat atatcaagga
     1681 tgaagacctt aaaacatttg cgcttgcatc tgcttatatc ggtaacgacg aaggtcatta
     1741 ctatagaaat aatcctgata aaggttttac agacctaaag aactacctac acggagttat
     1801 tcactacatg gaaatgaaac tcaatttcct tgatgctcaa gagcttgtga atcgttcaaa
     1861 gaaatcttag aatctacttc atccaacttc tcagctatat atgtcacagt cctcaatatc
     1921 tcattgaggg ctgttctttc tagttcgttc atttgcctta cctccttttc cttaagcttg
     1981 atttaattat aatacgattt tttcgtattg tcaatagttt ttatcaaaaa aataggattt
     2041 tttcgtattt ttgattgttt atcattcaaa aatgatatat aatgtaatta taaaaaatac
     2101 gaggtaatcg taaatggacg aaaaaaaacg aatgcaaatt attgctgaaa atattacaca
     2161 ctttagaaag caacgtggca tcacccaaaa agagttggct aaagaagttg gaattacagc
     2221 aagtactatg acagactata tgaagttaag aagcgctcct tcttttggtg ttatccaaaa
     2281 actggctgat tatttcggtg ttaaaaaatc agatatagat actactttta aagaagaatc
     2341 caccaactca ctgccagacg ctccagattc gctcacacag cagataatgg ataaggtagt
     2401 gcaattaacc ccacccaatc aaaaaatcgt gctacggacc tctgaggagc ttctggagag
     2461 ccaaaacgaa gaagaaacga agataaacga agtatcggaa gttatcagct tgtaccaagt
     2521 tgaggttgta tctgagacgg cagcagcttc tggatttaac tatggatttg ggtacgacga
     2581 tacagacaga gagactatag aggttgacga gcgaccacca cgccacgata ttgcgaccaa
     2641 ggtcagtgga gactccatgc aacccgacta ccaagacgga gacattctct atttagtaga
     2701 caaaggactg actacctaca acggagattt agcaattatc gcatatggag accgttctta
     2761 cttcaagaag atatataccg aaaacggacg cttacgccta gtgtcactca atgacaagta
     2821 cgaagacatc atcctagact tcccaccagc cgaagacaca cacatcaaga tttatgcagt
     2881 agtcggggtg tatagagggg aataaaaaaa ttatttttta aaaatattaa aaaacagttg
     2941 acttttttaa aaaaatcatt tagaatgaat tcattagaga aaaagcgtcg ggatctctac
     3001 ggggaccgat acggggaaac tccttcattc taaattagaa tgggggagtt tttttgaagc
     3061 catttaaaac aatcgaggaa caaatcgcaa cactaaaaat cagagggtta tccattacag
     3121 atgaatctaa agcagctaag tacctgctaa gtaacaatta ctacaatatt atcaatggat
     3181 acagtaagtt ttttcaacac cctggtactg acacttatat tgacggcgtc acatttgacg
     3241 aagtttcaag tctctataca tttgacaaag atgtaaaacg agccattttg caagctattc
     3301 ttgaagctga acaccatatc aagtcaatca ctgctcacag attcgccgaa gcttacccca
     3361 gtcaaaaata cgcttattta aacaccaatt cttatgcaga taataaaata ttagacgtgg
     3421 gatttattgt atcaaaacta tccaaaatca taaacacaaa caagcgatac agaggaaatt
     3481 caattcacca ctacgcacat actcattcag atgtcccaat ctgggtacta actgattatc
     3541 tagagtttgg agatttacgc acgattattg aaaacctgcc taattcactc caaaatgaaa
     3601 tcgcacggga tttagtaagt tttataagca caaacatacc tgactttaac gatgttttcc
     3661 caccagaaac cttgatatct tttctaaaaa atattaacga ggtacgaaac aaatgcgctc
     3721 acaataatcg cttattaaac ttcagatgcc gttctaatag tacgttttgg gaaacgattc
     3781 ataacaaaga gatcttgatg ggagatgaca gtagaaaaac tgtatattca acaattatta
     3841 gccttcaatg ctttattagt aaagcagcat tcaacatttt gtggaatact cttagaaaaa
     3901 aagttatcaa actagagaaa aagctgcctt ctatagacat caatgtaatc aaccagtctt
     3961 taggttttcc taatgattgg caccgtaatg aaccaaaagt ataaattaaa accaactatt
     4021 tccatttagg aaataactgc ttgacagaaa ttaaaaaaag aaatacacta agaatgtaaa
     4081 aaagccttgt tcgtcaagga taaaatcgtc tggtgtactt ctaagaggta caccttattt
     4141 tattatctga cgagatagca accaaaaaat ccccacactc aaattttggc caaggagagt
     4201 gtgaggaaat catgtatagg aaacaaccat taaaaaggta gttttcttgt acccatttta
     4261 acaaaaaagt gaggtaaacg caatgtggat ggaagaattg ccaaatggca aatttaaata
     4321 ttttgagcga tataaagatc catatactga gaaattaaaa aaagtttcag taaccatgga
     4381 gaagaaaact ccccaggcaa gaaatcaagc tgctatcttg ttacaagaga agataaataa
     4441 aaaactcagc acaaaacaag tagaaagcat tacatttgaa gaaatctata accttttcta
     4501 taaatcatgg gcgcaaacag taaaggaatc aacaaaacat aattgtaaat cagttgataa
     4561 gaagatgaag gaagtcatac catccgatac catacttgct aatcttgaca ggcgttttct
     4621 tcaagaggct attgaaaaaa ttattgaaag caacggatat attacagcta aaaaagtacg
     4681 gcataggctc agaggtatct ttaattacgc tgttcaatac tcttacattg aaaacaacga
     4741 ggtcgattat actacgattc ctcaaaaacc aaagacttta gaagaactgg aaaaaaagcg
     4801 taacaacttt ctcaccatgc aagaaataaa agcacttgtc gatgtcctta atcgtcgaga
     4861 atatcaccaa aagtacgctg atatggttct tgtgctgaca ttaactggta tgagatatgg
     4921 tgagttaact gccttacaac tgaagaatat agacttcgaa aacaacaaaa ttgagatcac
     4981 aggtaatttt gattcagtaa acaaaatcaa gacgctacca aagactacaa attcaatacg
     5041 gacaatcaaa gtatcagaga gtgtcataga agctattcaa agacaaatag tacgacttag
     5101 cgaacgtttc cagccattgt caagcgatga ttatattttc tgttttgaaa aatggaatca
     5161 acctacaaca atagcttgct tcatacagat attaaaaaaa tatggaaaac aggccaaaat
     5221 agaaaaaaac ttatctagcc atatttttag gcattctcat atttcgtttt tagcagagtc
     5281 tgacctccca ataaaatcaa taatggatcg agttgggcac tcaaatgcaa aaatgacttt
     5341 ggaaatctat tctcatacta ctgaggatat ggaggataaa ctggtcaata aattagatac
     5401 tattttttaa ttctgcccct tgattgcccc tttttgattt cataacacaa caaaacccct
     5461 tgaagatatt gataattcaa ggggttgctt tatatcgtta taattcatcc gctatcttat
     5521 tgatttttct gagtctgtga ttgacaccac ttttggtcag aggggtgctg agactatctg
     5581 ctaactgctg gatagagtag tctgggtgct gaatcctcag ttgcgccact tcctgcaaat
     5641 ctactggcaa attttctaag cccatgatat ctttgatttt actgatattg ttaatggtct
     5701 tcatgctggc agaaactgtc cgagcgatat tagctgtctc ggcattatta gcccgattga
     5761 ggtcgttacg ggtttctcgc aaaatcttaa cccgctcaaa atcatcacgt gcctgcatgg
     5821 ctcctattac tatcaagaag tccataatgt cttctgctcg ctggagatag gtcacagccc
     5881 ccttcttgcg ctcaagcacc ttggcatcca gtaaaaactg ttggagaagg gaggcaattc
     5941 cttgcgcgtg gtccagataa acagaactga tttccaactg gtacttgcct gactcagggt
     6001 cacgaatgct cccatttgcc aagaaagcgc cacagagata ggcacgacct gcttcctcat
     6061 ccgataaaat cgcctcatca atacctgttt ccaggccaaa gaaagagtct gccaagtgca
     6121 aatcacttaa caaatcctgc accttttcat ctgtaaaaac ggtatagacg cgattcttgc
     6181 gaagattgct ccgttggtgg tgacgaattt cagatttgat ttcatagaaa tggagaaagg
     6241 actcatagag gtgacgggcc agtttggcat tttctgtcac aactgacaaa gtcaagcccg
     6301 aagtcgagag accgatgcta ccagacattt tgataatggc agataattca tgccagctca
     6361 gatggtgttg gcccaggatt tcttctttta ctgctactgt gaaactcatt ttttcacctg
     6421 tataatgcgc atcaactcgt ccacaatcaa atctccatcg tggaaggcac cgccattttc
     6481 cagacgaagg aagttagatg aaatcacgcg cgaaacttgc ttacaaagac ctacaaaatc
     6541 gtgttccact tgcaccaagt attcatcaaa acggttggaa ttcatgtatt cctgaggcac
     6601 tttttcaata ttcaccaaga cagtgtcgat aaaagggcga ccaaggtgac gatgcaagac
     6661 ttccacgtgg tcgctatctg taaagtgttc cgtctcccca cgttgggtca tgatattgca
     6721 gacataggca atttctgcct tagtttccaa aagagcccgc ccaatttcct taatcacgat
     6781 attgggcaaa atagaggtaa agagggaacc tggccctagg acaatcatgt cactttcaag
     6841 gatggtctgc actactcgac ggctggccag aggcgtatca tcgtttaggg cattggtcac
     6901 atagacattg tcaattatgc ctcgatggtc tacaatatga ctctctccag ccacttctgt
     6961 cccatcctga aagactgcat gaagggtcaa aggatggtca ctggaaggat aaattttccc
     7021 tgttgtatgg aaaaatttgc tcaataactg catggcatta taggttgaac cctgcatttc
     7081 tgacaagcca gcaatgatga gatttcccaa tggatggcca gcaaaggctc cggcatcctc
     7141 agagaaccga tactgaaaga ccttctcata aaacttaggc atatccgaca tggccacaag
     7201 gacattacga agatcacctg gcggtgtcaa ctgttgcata ttttttcgga gttcacctga
     7261 agaaccacca tcatctgcca ccgtcacgat agctgcgatt tccacatctt tttcccgcag
     7321 actttttaga atgacgggaa ttccagtccc tccaccaatc accgttatct ttggttttct
     7381 catgaacggt ttaccgtttc ctttctgcgg tctttgtcgc gatgcccttc attaacagac
     7441 caattcttgg ataagtcctg cgccaagcgt ttagcaaatg ccacactacg gtgttgtcca
     7501 cccgtacatc ccatggcaat ggtcaaaacg gacttacctt ccttttggta acttggcaga
     7561 atcggctcaa tcaaggccaa taaatgttga taaaagtctt ctgactcagg atggttcatg
     7621 acataatcat aaacaggttc atccacaccc gtttggtttc tcagttctgg tagataatag
     7681 ggatttggca agaaacggac atcaaagacc aagtccgcat caatcgggat tccatactta
     7741 aatccgaaag acatgacttc gatacggaaa gactgggctt gttcttggtc tgaaaactgc
     7801 tctgcaaggg ttttgcgcag ctcacgtgga gtgagttcag tcgtatccac cacattttgg
     7861 ctcatatttt tcaaaggtgc caagagttca cgttccaact tgattccatc taaaatacga
     7921 ccgtctgctg ctagtgggtg actccgtctg gtttccttgt aacgagcgac caattcctta
     7981 tcagccgcat ccaaaaagag gattttgaaa tccaaaccat cttgattttc caactcatcc
     8041 aaaacagctt gaatctctga aaagaaagaa cggctacgca tatccactac caaggccaac
     8101 ttaggattgt cttccttaat ttcaaccagc tgcaaaaact taggcaagag agctggcggc
     8161 atattatcaa tggtgaaata acctagatcc tcgaaggact gaatggctac agttttccct
     8221 gcgccactca tccctgtcac aatcaccaag tgaaattgtt tctttgtcat ctttttctcc
     8281 ttatatcaaa agaagtttgg caacaccaaa cttcaactag cttatccaat ctctgcgatg
     8341 acttcaattt cgacttttac atcacgagga agacgagcta cctccacagc tgaacgagct
     8401 gggaattcct ctttgaaggc cgtttggtaa acctcattaa aaggaacaaa gtcgttcata
     8461 tcgctcaaga agcaagttgt tttgacaaca tggtcaaagt ctgttcctgc ttctgccaaa
     8521 atagcaccga tgtttttcaa gacttgctct gtctgttctt ggatattctc tcctacaatt
     8581 tccccagttt caggggatag gggaacttga ccgctagcaa acaaaaggtt gccaacgatt
     8641 tttccttgaa catagggtcc gatagccttt ggggccttat ctgtatgaat tgtttttgcc
     8701 attttctttt cctcacaatt tttctaagat tgcatcccaa gcctcatcca tccctgcctt
     8761 gctgacagat gaaaagagga tgaaatcgtc actcgggtca aagtttaatt tctttttgat
     8821 tgctgattca tgcttgttcc atttaccacg aggaatcttg tccgccttgg tcgccacaat
     8881 gatgactgga atctcataat acttgagaaa ttcgtacatc tgcacatcat ctgctgacgg
     8941 gtcatgacga aggtcaacta gactgacaac cgcacggaga ttttcccgag tcgttaagta
     9001 ctcctcaatc atgcaccccc acttttcacg ttccttttta gaaacacgag catagccata
     9061 accaggcaca tccacaaagc gcatcttgtc atcaatgtta aaaaagttca ggagctgggt
     9121 tttaccaggt tttcctgatg tacgggcgag attcttacgg ttcaacatag tgttgataaa
     9181 gctggattta ccaacatttg aacgccctgc tagggcaatc tctggcagtt catcctgcgg
     9241 atagtgggac ttattagctg cactgagcaa gatttcagca ttgtgtgtat taagttccat
     9301 agtcacctct aggctgtttc taggatcggt ttatccgttc catcgacagt ttctttagtg
     9361 atgcgaacca atttcacatt ttcctgactc ggcacctcaa acataacatc tagcatggtt
     9421 tcttcgataa tggagcgaag tccacgcgcc cctgtcttcc gttcgattgc tttattagca
     9481 atctcttgaa gggcttcgtc gtcaaattcc aactcaacat catcataaga aagcaaagtt
     9541 tggtattgtt tcaccaaggc atttcttggc tctttcaaga tgcgaaccaa gtcatcaacg
     9601 gtcaattgct caagagccgc aaaaacaggc aagcgtccaa tcaactcagg gataatacca
     9661 aatttttgaa tgtcttcagc gatgatttct tgcatatatg agctgttttc gtcaatcgcc
     9721 ttattatttt gaccaaatcc gatgactttt tcacccagac gttgtttgac aatttcttca
     9781 ataccatcaa aagcaccacc cacgatgaag aggatatttt ttgtatccac ttgaatcatc
     9841 tcttgttgtg gatgtttgcg tccaccttga ggcggcacgc tagcaacagt tccctcgata
     9901 atcttgagaa gggcttgttg caccccttca ccagaaacat cacgtgtgat agacacattc
     9961 tcactcttct tggcaatctt gtcaatttca tccacataga taatgccacg ctctgcacgt
    10021 tcgatgttaa agtcagcaac ctgcaagagt ttgaggagga tattttccac gtcctcaccc
    10081 acataaccag cctccgtcag agctgtcgca tccgcaatag caaaaggcac attcaagctc
    10141 ttagccaagg tctgggcaag gaaagttttc cctgaaccag ttgggccaat catcaaaatg
    10201 tttgacttct gcaaatccac atcttctgac tcttcgcgtg tatcgtggaa attgatgcgt
    10261 ttgtagtggt tataaaccgc cactgccaag gcacgcttgg cacgatcttg accaattaca
    10321 tagtggttca agatatggag gagttcaatt ggttttggca cctcagacaa gtctgccaag
    10381 acttcctcaa ccaattcttc tcgaatgatt tcctgagcta actccacgca ttcattacaa
    10441 ataaaagcat tgttgccagc aattattttt tgtacttctt cttggttttt gccacaaaat
    10501 gagcaataaa ccatcatatc attttttcta tttgtagaca tgatttcctt ccattctata
    10561 ctgtcattct atctaaaata aggtcatgta aaaagcatga atactattga ccagattggt
    10621 aaaggcattt aaccaaagga ggatagaaag cccgtaacgc tttttacgaa aagcctgtgc
    10681 tcctgccaga aagcagatga aacacagaaa agccgtgaat agaccaaata aactccgttc
    10741 cattagactt cctttctctt gcggtattgg atggtaaaat cataaggatt cttctcatct
    10801 ttggcgtaaa atttgcttga aactgtctca aaaagagaca agtcaagctc ttcagggaaa
    10861 taggtatctc cttccacccg agcatgaatg tgagtgacaa tcacttcatc aaggtaaggt
    10921 tcaaaagcct gaaaaatttg cttcccaccg ataatgtaga gattcttttc ttgatcctga
    10981 taccagtcaa gaacagactg gacgtcctga aaagtagcaa ccccatctat cttttcttcc
    11041 ggattacgcg tcaaaatcag ggtttcccgt tttggaagca agcgacgccc catcccatca
    11101 aaggtcacac gccccatcaa gatagcatga ttcagagttg tttctttaaa gtgctgcaat
    11161 tctgctggca aatgccaagg cagacgattt tccttaccaa tcacaccctc ttcatcctgg
    11221 gcccaaatag ctacgatttt cttagtcatg cttccatcct tttcactgat agtactattt
    11281 tatcaaaaaa ctcaaaaaaa gactggtttg gaatagctta caaaatagaa aaaatctgta
    11341 agaaatttcc tacagattta tctatgtttc cttatttctt acaaaccagg tgcttgtcca
    11401 agttcggctg caagcatcca aattgtttta tctgtttcag ttttagcgcc tgcaaagata
    11461 ccgtttgtta catcgtcacc ttcttcatca gtgacatcca aacctttttg gaaaagttct
    11521 gacaagtaac ggtagataac aagaacacgt tccaagcttt cttcaacatt acggtattca
    11581 ccagcttctt cttcgatttc actattttga aggaactctg tcaatgtaga gaatgggctt
    11641 ccaccgagtg taatcaagcg ttcgctgatt tcatccaatt gaccgtcaag agcttccatg
    11701 tactcatcca tttttggatg ccatacaagg aaaccacgac catgcatata ccagtgcact
    11761 tggtgcaaag caacgtgagc tacatacaaa tcagcaacag cttggttcaa gacttccttt
    11821 gtttttgcca atgctactgg cgctgctttt gtcaatgatg ttacgtcttt tactgcttct
    11881 tttttcaatt ctaccatttt ctttacctca ttcattattt tttgtaacca cttcttaatg
    11941 attactacct tagtatacta ctaaggaaaa ccaatagcaa gacaaagaac ttatatgaga
    12001 aaagttgcaa tagactgata atttaagaat tctttagaag acaaaaaaga gggttggatg
    12061 cttatagtca atggaaatcc atcagcaaac taggaaacta aacccagctt gaccaaagca
    12121 caagttttga ggtcgcaggt agaactgacc aagctgatgt ggtttgaaga aattccccaa
    12181 tactataata gattgaaata agatgaaacc aagtcgatta ggaaaggtaa atgaatttct
    12241 aaaatgtttt accaatcaca aggtctttgt ctatattcaa tctactatat aagcttcatt
    12301 tccgagcaag atcttgaatt tactcgagga tgaactatca taaaacaaag aaaaagaggg
    12361 tgctactatc acatccctct ttcaaat
//
LOCUS       DAVKMJ010000049        12081 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000049 DAVKMJ010000000
VERSION     DAVKMJ010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12081
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.049"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(195..1826)
                     /locus_tag="VW348_001762"
     CDS             complement(195..1826)
                     /locus_tag="VW348_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEU9746627.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGIGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNIIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2119..7098
                     /locus_tag="VW348_001763"
     CDS             2119..7098
                     /locus_tag="VW348_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEU9746628.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLHYQGHEVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFTEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELTTAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELTFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNKVLPKPTYQPTSDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            7188..8384
                     /locus_tag="VW348_001764"
     CDS             7188..8384
                     /locus_tag="VW348_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEU9746629.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8520..9047
                     /locus_tag="VW348_001765"
     CDS             8520..9047
                     /locus_tag="VW348_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEU9746630.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRVRLFLEKKEK"
     gene            9124..9480
                     /gene="glnR"
                     /locus_tag="VW348_001766"
     CDS             9124..9480
                     /gene="glnR"
                     /locus_tag="VW348_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEU9746631.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9517..10863
                     /gene="glnA"
                     /locus_tag="VW348_001767"
     CDS             9517..10863
                     /gene="glnA"
                     /locus_tag="VW348_001767"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEU9746632.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10959..11078)
                     /locus_tag="VW348_001768"
     CDS             complement(10959..11078)
                     /locus_tag="VW348_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEU9746633.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            11336..11473
                     /locus_tag="VW348_001769"
     CDS             11336..11473
                     /locus_tag="VW348_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746634.1"
                     /translation="MNPDRAEEYFCRGCQGENPEDIEFYDEQLQAEKVEVLNIRLEVK
                     N"
     gene            11566..12081
                     /locus_tag="VW348_001770"
                     /pseudo
     CDS             11566..12081
                     /locus_tag="VW348_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187262.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         3893 a         2207 c         2583 g         3398 t
ORIGIN      
        1 aatttaatcc attatagtaa aatgaaataa taacaggaca aatcgatttc taacaatgtt
       61 ttagaaatag aggtgtacta ttctagtttc aatatactat atatctgcag aatactcttt
      121 cagtttcatt cagcctagtc ttgcttagga aaaagtaaga agccatccaa ttatgatgga
      181 tagcttcttg gttattagat ttgttctgca aaaacctttt cagcaaggtt catagcgtgg
      241 tctgatacac gagtgtagtg tgagatgatg tcgataaagt tgaccccagc ttgtgttgaa
      301 cattcgcctt tgttgaggcg tttgatgtgg gtttttctga gaacacgttc tatcttattg
      361 attgcttcat gacgttctac aagactgcgt gctttttcaa tatcattgtt ttccacacta
      421 tccagagcat ctttgataaa gtcactagtt tggcggtaaa cttcctctaa ttctttcaag
      481 gcggcatcag aaaattcaac atttttccgt tgaagatagt cagtcagatt gagtagagcc
      541 tccgtgtggt ctccaatccg ttccaaatca cgggaggaat caaggatatt ggtaagcact
      601 tcactttctt tttggctgag agcttcgctt gaaagggcaa tgagataacg tgttaattgc
      661 tcatcgatgg tgttaattgc ttcttcggtt ttatgccctt tttcagcaac tttttcatcc
      721 aagtcaatga tgtacttata ggaaaggtca aaggctttag cagcgtagtt tcctaagtgc
      781 aagagctctt tcttagcatt tcctagagcg atagatgggg cctgtttgat gaaatgttca
      841 tcaagatata agggttcgta tttgacaacc tcgtcctctc caggaataat cttggttaca
      901 aagtaagcca gagctccgat aaatggaaat tggacaatgg tgttggtaat attaaaggtt
      961 ccgtgagcaa aggcgatggt catttccggt gctagattta gcgtagcttc aaaccaatga
     1021 atcaggacag taaaaggaac tagaaaaata acgcagacga ctgttccgat aatgttgaag
     1081 gcaacatgag ctcctgctac ccgtttagct gcaatattag cccctaaaga ggcaatgatg
     1141 gctgtaatgg ttgtcccgat attgtcacca aatagaactg gcaaagctcc ctgtaggtca
     1201 attagattgc cggcgtagag gttttgtaaa atcccaatgg tagccgaaga agcttgaatt
     1261 agcaaggtca agccagtacc gacaaagaca cccaaaacag gattcttact tagctcaatc
     1321 atatagtcct taaagacctg taaatccttg agtggagcca ttgcgccgct catgagattg
     1381 agggcaaaaa agataccacc gataccaaag aggatgcgtc cgatattatt gactgtccga
     1441 tttttcgtaa aaaagagaca gacggcaccg ataaagagca taggtagggc atagttacct
     1501 aatttaaaac cgatgagaaa ggatgtgaca gttgtcccaa tattagcacc catgacaatc
     1561 ccgatagcct gacgtaaggt taagagaccg gcactgacca ggccgactgt aataactgtt
     1621 acaccagaac tagactgaat tagagcagtc atcccaatac caaccagaac tccaaagaaa
     1681 ggattactag tatatttgtc aatgtaaaaa cgaaggcgat ctccagcagc ttgttgcaaa
     1741 ccgtctccca tggtcttgat gctatataag aatagcccca gaccacctaa aaagtgaaat
     1801 aaaatttcct gccaattaat ggacatttct ttttcctccg aaaaataatc gcggaatatc
     1861 tcctattcta ttttaaagga taaaagtaaa tctaacaagt gttaacgtca agtttgtaaa
     1921 agaaaattat aattgataag tgtattattt ttaagagttt ttaaccttat tttagattta
     1981 tgaaagcagc tattgttttt tgtctaaaaa tgttttagga taaaaatgtg attatcatgg
     2041 ttctagagtt tgataaaaaa ctacagaata taaagcgctt tcttgaaaac aacaaaatca
     2101 atcttttagg aggagaaaat gaagaatcca ttttttgaaa gacgttgtcg ttacagtatt
     2161 cgtaagttat cagtaggagc ctgctcgctg atgattggtg ctgttttatt tgctggtcca
     2221 gccttggctg aagaaactgc agttcctgaa aatagcggag ctaatacaga gcttgtttca
     2281 ggagagagtg agcattcgac caatgaagct gataagcaga atgaagggga acatgctaga
     2341 gaaaacaagc tagaaaaggc agaaggagta gcgatagcat ctgaaactgc ttcgccagca
     2401 agcaatgaag ctgcaactac tgaaactgca gaagcagcta gcgcagctaa accagaggaa
     2461 aaagcaagtg aggtggttgc agaaacacca tctgcagaag caaaacctaa gtctgacaag
     2521 gaaacagaag caaagcccga agcaactaac caaggggatg agtctaaacc agcagcagaa
     2581 gctaataaga ctgaaaaaga agtccagcca gatgtcccta aaaatacaga aaaaacatta
     2641 aaaccaaagg aaatcaaatt taattcttgg gaagaattgt taaaatggga accaggtgct
     2701 cgtgaagacg atgctattaa ccgcggatct gttgtcctcg cttcacgtcg gacaggtcat
     2761 ttagtcaatg aaaaagctag caaggaagca aaagttcaag ccttatcaaa caccaattct
     2821 aaagcaaaag accatgcttc tgttggtgga gaagagttca aggcctatgc ttttgactat
     2881 tggcaatatc tagattcaat ggtcttctgg gaaggtctcg taccaactcc tgacgttatt
     2941 gatgcaggtc accgtaacgg ggttcctgta tacggtacac tcttcttcaa ctggtctaat
     3001 agtattgcag atcaagaaag atttgctgaa gctttgaagc aagacgcaga tggtagcttc
     3061 ccaattgccc gtaaattggt agacatggca aagtattatg gctatgatgg ctatttcatc
     3121 aaccaagaaa caactggaga tttggttaaa cctcttggag aaaagatgcg ccagtttatg
     3181 ctctatagca aggaatatgc tgctaaggta aaccatccaa tcaagtattc ttggtatgat
     3241 gccatgacct ataactatgg acgttaccat caagatggtt tgggagaata caactaccaa
     3301 ttcatgcaac cagaaggaga taaggttccg gcagataact tctttgctaa ctttaactgg
     3361 gataaggcta aaaatgatta cactattgca actgccaact ggattggtcg taatccttat
     3421 gatgtatttg caggtttgga attgcaacag ggtggttcct acaagacaaa ggttaagtgg
     3481 aatgacattt tagacgaaaa tgggaaattg cgcctttctc ttggtttatt tgccccagat
     3541 accattacaa gtttaggaaa aactggtgaa gattatcata aaaatgaaga tatcttcttt
     3601 acaggttatc aaggagaccc cactggccaa aaaccaggtg acaaagattg gtatggtatt
     3661 gctaacctag ttgcggaccg tacgccagcg gtaggtaata cttttactac ttcttttaat
     3721 acaggtcatg gtaaaaaatg gttcgtagat ggtaaggttt ctaaggattc tgagtggaat
     3781 tatcgttcag tatcaggtgt tcttccaaca tggcgctggt ggcagacttc aacaggggaa
     3841 aaacttcgtg cagaatatga ttttacagat gcctataatg gcggaaattc ccttaaattc
     3901 tctggtgatg tagctggtaa gacagatcag gatgtgagac tttattctac taagttagaa
     3961 gtaactgaga agaccaaact tcgtgttgcc cacaagggag gaaaaggttc taaagtttat
     4021 atggcattct ctacaactcc agactacaaa ttcgatgatg cagatgcatg gaaagagcta
     4081 accctttctg acaactggac aaatgaagaa tttgatctta gctcactagc gggtaaaacc
     4141 atctatgcag tcaaactatt tttcgagcat gaaggtgctg taaaagatta tcagtttaac
     4201 ctaggacaat taactatctc ggacaatcac caagagccac aatcgccgac aagcttttct
     4261 gtagtgaaac aatctcttaa aaatgcccaa gaagcggaag cagttgtgca atttaaaggc
     4321 aacaaggatg cagatttcta tgaagtttat gaaaaagatg gagacagctg gaaattacta
     4381 actggctcat cttctacaac tatttatcta ccaaaagtta gccgctcagc aagtgctcag
     4441 ggtacaactc aagaactgaa ggttgtagca gtcggtaaaa atggagttcg ttcagaagct
     4501 gcaaccacaa cctttgattg gggtatgact gtaaaagata ccagcctacc aaaaccacta
     4561 gctgaaaata tcgttccagg tgcaacagtt attgatagta ctttccctaa gactgaaggt
     4621 ggagaaggta ttgaaggtat gttgaacggt accattacta gcttgtcaga taaatggtct
     4681 tcagctcagt tgagtggtag tgtggatatt cgtttgacca agccacgtac cgttgttaga
     4741 tgggtcatgg atcatgcagg agctggtggt gagtctgtta acgatggctt gatgaacact
     4801 aaagactttg acctttatta taaagatgca gatggtgagt ggaagctagc taaggaagtc
     4861 cgtggtaaca aagcacacgt gacagatatc actcttgata aaccaatcac tgctcaagac
     4921 tggcgcttga atgttgtcac ttctgacaat ggaactccat ggaaggctat tcgtatctat
     4981 aactggaaaa tgtatgaaaa gcttgatact gagagtgtca atattccgat ggccaaggct
     5041 gcagcccgtt ctctaggcaa taacaaggta caagttggct ttgcagatgt accggctgga
     5101 gcaactatta ccgtttatga taatccaaat tctcaaactc cgctcgcaac cttgaagagc
     5161 gaagttggag gagacctagc aagtgcacca ttggatttga caaatcaatc tggtcttctt
     5221 tattatcgta cccagttgcc aggcaaggaa attagtaatg tcctagcagt ttccgttcca
     5281 aaagatgaca gaagaatcaa gtcagtcagc ctagaaacag gacctaagaa aacaagctac
     5341 gccgaagggg aggatttgga ccttagaggt ggtgttcttc gagttcagta tgaaggagga
     5401 actgaggacg aactcattcg cctaactcac gcaggtgtat cagtatcagg ttttgatacg
     5461 catcataagg gagaacagaa tcttactctc caatatttgg gacaaccggt aaatgctaat
     5521 ttgtcagtga ctgtcactgg ccaagacgaa gcaagtccga aaactatttt gggaattgaa
     5581 gtaagtcagg aaccgaaaaa agattaccta gttggtgata gcttagactt gtctgaagga
     5641 cgctttgcag tggcttatag caatgacacc atggaagaac attcctttac tgatgaggga
     5701 gttgaaattt ctggttacga tgctcaaaag actggtcgtc aaaccttgac gcttcattac
     5761 caaggccatg aagttagctt tgatgttttg gtatctccaa aagcagcatt gaacgatgag
     5821 tacctcaaac aaaaattagc agaagttgaa gctgctaaga acaaggtggt ctataacttt
     5881 gcttcatcag aagtaaaaga agccttcttg aaagcaattg aagcggccga acaagtgttg
     5941 aaagaccatg aaactagcac ccaagatcaa gtcaatgacc gacttaataa attgacagaa
     6001 gctcataaag ctctgaatgg tcaagagaaa tttacggaag aaaagacaga gcttgatcgc
     6061 ttaacaggtg aggttcaaga actcttggct gccaaaccaa accatccttc aggttctgcc
     6121 ctagctccgc ttcttgagaa aaacaaggcc ttggttgaaa aagtagattt gagtccagaa
     6181 gagcttacaa cagcgaaaca gagtctaaaa gatctggttg ctttattgaa agaagacaag
     6241 ccagcagtct tttctgatag taaaacaggt gttgaagtac acttctcaaa taaagagaag
     6301 actgtcatca agggtttgaa agtagagcgt gttcaagcaa gtgctgaaga gaagaaatac
     6361 tttgctggag aagatgctca tgtctttgaa atagaaggtt tggatgaaaa aggtcaagat
     6421 gttgatctct cttacgcttc tattgtgaaa atcccaattg aaaaagataa gaaagttaag
     6481 aaagtatttt tcttacctga aggcaaagag gcagtagaat tgacttttga acaaacggat
     6541 agtcatgtta tctttacagc accacacttt actcattatg cctttgttta tgaatctgct
     6601 gaaaaaccac aacctgctaa accagcacca caaaacaaag tccttccaaa acctacttat
     6661 caaccgactt ctgatcaaca aaaggctcct aaattggaag ttcaagagga aaaggttgcc
     6721 tttcatcgtc aagagcatga aaatgctgag atgctagttg gggaacaacg agtcatcata
     6781 cagggacgag atggactgtt aagacatgtc tttgaagttg atgaaaacgg tcagcgtcgt
     6841 cttcgttcaa cagaagtcat ccaagaagcg attccagaaa ttgttgaaat tggaacaaaa
     6901 gtaaaaacag taccagcagt agtagctaca caggaaaaac cagctcaaaa tacagcagtt
     6961 aaatcagaag aagcaagcaa acaattgcca aatacaggaa cagctgatgc taatgaagcc
     7021 ctaatagcag gcttagccag cctcggtctt gctagtttag ccttgacctt gagacggaaa
     7081 agagaagata aagattaaat atcgaaaaat cttgtgaaat ctttccttat atttccaaag
     7141 tgtgatataa tagtttcgaa taaaataaat aaaggagttt ttgtaacatg gcaaaactta
     7201 ctgttaaaga cgttgacttg aaaggtaaaa aagtcctcgt tcgtgttgac ttcaacgtac
     7261 cattgaaaga tggcgtaatc actaacgata accgtatcac agcagctctt ccaactatta
     7321 agtacatcat cgaacaaggt ggacgtgcaa ttcttttctc tcaccttgga cgtgtgaaag
     7381 aagaagctga taaagctggt aaatcacttg ctcctgtagc agctgacttg gcagcaaaac
     7441 ttggtcaaga tgttgttttc ccaggtgtca ctcgtggtgc tgaattggaa gcggcaatca
     7501 acgctcttga agatggacaa gttctcttgg ttgaaaacac tcgttacgaa gatgttgacg
     7561 gcaagaaaga atctaaaaac gatcctgaac ttggtaaata ctgggcatca cttggagatg
     7621 gtatcttcgt aaacgatgca ttcggtacag ctcaccgtgc acacgcatct aacgttggta
     7681 tctcagcaaa cgttgaaaaa gcagttgctg gtttccttct tgaaaacgaa attgcctaca
     7741 tccaagaagc agttgaaact ccagaacgtc cattcgtggc tatccttggt ggttcaaaag
     7801 tttcagacaa gatcggtgtt atcgaaaact tgcttgaaaa agctgataaa gtccttatcg
     7861 gtggtgggat gacttacaca ttctacaaag cacaaggtat cgaaatcggt aactcacttg
     7921 tagaagaaga caaattggat gttgcgaaag ctcttcttga aaaagcaaat ggtaaattga
     7981 tcttgccagt tgactcaaaa gaagctaacg catttgctgg ttacactgaa gtgcgtgaca
     8041 ctgaaggtga agcagtttct gaaggcttcc ttggtcttga catcggtcca aaatctatcg
     8101 ccaaatttga cgaagctttg actggtgcca aaacagttgt atggaacgga cctatgggtg
     8161 tatttgaaaa cccagatttc caagctggta caatcggtgt gatggacgct atcgtgaaac
     8221 aaccaggagt taaatcaatc atcggtggtg gtgactcagc tgccgcagcg attaaccttg
     8281 gccgtgcaga caagttctca tggattagta cgggtggtgg agcatcaatg gaacttcttg
     8341 aaggtaaggt tcttccagga cttgcagccc tgacagaaaa ataagatttt ataaacaaat
     8401 caaagaagag agggatgaaa gttcctcttt tcttttgctt aaaataaaaa cgcttcctct
     8461 caactattac tcataaaaat caccgattta tgataaaatg gaaatagaaa gttgagatta
     8521 tgagttattt taaaaaatat aaattcgata aatcccagtt caaacttggt atgcgaacct
     8581 ttaaaacagg tattgctgtt tttctagttc tcttgatttt tggctttttt ggctggaaag
     8641 gtcttcaaat tggtgctttg acagccgttt ttagcctgag ggagagtttt gatgagagtg
     8701 ttcattttgg gacttcgcgt attctaggaa atagtatcgg tggactctat gccttggtct
     8761 tcttcttatt aaataccttt ttccacgaag ccttttgggt gaccttggta gttgttccaa
     8821 tctgcaccat gttaaccatt atgacaaatg tagccatgaa taacaaagca ggggttattg
     8881 gtggtgtagc agctatgtta atcattaccc tatcaattcc aagtggtgag acaatttcgt
     8941 acgtgtttgt gcgtgtatca gaaacgttta tgggagtttt tgtcgcaatt atcgtaaatt
     9001 acgatattga tcgtgttcgt ctctttttag agaaaaaaga aaaataatgt tacattttat
     9061 aacattatca attgacgttt gtcttttttt agactataat agacagaaag aaggaaattg
     9121 taaatgaagg aaaaagaatt tcgccgaaat atggctgttt ttcctatcgg cagtgttatg
     9181 aagttgaccg atctatcggc gcgtcagatt cgttattatg aagatcaaga gttgatcaag
     9241 cccgatcgaa acgaaggaaa tcgtcgcatg tattccttga atgacatgga tcgtctgctt
     9301 gaaatcaaag attatatctc tgaaggttat aatatcgctg ccattaagaa aaaatatgct
     9361 gaacgtgaag cgaaatccaa gaaagcggtt agtcagactg aagtacgtcg tgcacttcac
     9421 aatgaactcc tccaacaggg gcgttttgct tcagtacagt caccttttgg tcgcggttag
     9481 gcaaccgcaa gtagtcatag attaaggaga aaacttatgc caatcacagc tgcagatatt
     9541 cgtcgtgaag tcaaggaaaa aaatgttacc tttattcgtc ttatgttctc agatattttg
     9601 ggaaccatga aaaacgtcga aattcctgct acagatgaac agttagataa ggttttgtcg
     9661 aacaaggtta tgtttgatgg atcttctatt gaaggttttg tacgtatcaa tgagtcggat
     9721 atgtacttgt acccggactt ggatacatgg acagtcttcc cttggggaga tgaaaatgga
     9781 agtgttgcag gtctgatctg tgatgtctat acaacagaag gtgaaccatt tgcgggtgac
     9841 cctcgtggta atttgaaacg agctcttcgt cacatggaag aagttggatt caaatccttc
     9901 aaccttggtc cagagccaga attcttccta tttaagttgg atgaaaatgg ggacccaaca
     9961 cttgaagtga atgacaaggg tggctacttt gatttggcac ctactgacct tgcggacaac
    10021 acacgtcgtg agattgtgaa tgtcttgacc aaaatgggat ttgaagtaga agcgagtcac
    10081 cacgaggttg cggttggaca gcatgagatt gactttaagt acgatgaagt tctccgtgct
    10141 tgtgataaga ttcaaatctt taaacttgtt gttaaaacca ttgctcgcaa acacggactt
    10201 tacgcaacat ttatggcgaa gccaaaattt ggtattgctg gctcaggtat gcactgtaat
    10261 atgtccttgt ttgatgcaga aggaaataac gccttctttg atccaaatga tccaaaagga
    10321 atgcagttgt cagaaacagc ttaccatttc ctaggcggtt tgatcaagca tgcttacaac
    10381 tatactgcca tcatgaaccc aacagttaac tcatacaaac gtttggttcc aggttatgaa
    10441 gcgcctgttt acattgcttg ggctggtcgt aaccgttcgc cacttgtgcg cgtacctgct
    10501 tcacgtggta tgggaactcg tcttgagttg cgttcagtgg atccaatggc gaacccttac
    10561 attgctatgg ctgttctttt ggaagttggt ttgtatggta ttgaaaataa aatcgaagca
    10621 ccagctccta tcgaagaaaa tatctacatc atgacagcag aagagcgcaa ggaagctggt
    10681 attacagacc ttccatcaac tcttcacaac gctttgaaag ctttgacaga agatgaagtg
    10741 gttaaagctg ctctcggaga tcacatctac actagcttcc ttgaagccaa acgaatcgaa
    10801 tgggcaagtt atgcaacctt cgtttcacaa tgggaaattg ataattattt agacctttac
    10861 taatactaat atagaagaaa gattgcctgt gggtaaacag tcacacagca gtctaagcca
    10921 tcaaatacct ataaccctta aaatagcgat ttcggtcgct atttattttt cgaaaaatcc
    10981 tcttgactct tttgcgaatt agatttatca tcagacgtgt agaagaaaat taaggagtca
    11041 ctatggaaaa attcaatttc aaaaacaata tcgggcaaga aaacaagtta cttcaaatcg
    11101 aaatctacaa gtttactaac ttttgcaagc ttcaaaatta cacatctgta aatatttttt
    11161 cgaaagatat atttgaagcc atagtaaatt gagactagaa tggtacacta catctgctaa
    11221 aaatttctag aaactaattt aactttccta atcgatttgt ttacatctta tttcaatcta
    11281 ctatattatc tcaataaatg atgatggcga ctgttttgtt tgtgcttgtc gatttttgaa
    11341 tcctgatcga gcggaagaat atttctgccg aggttgccaa ggggaaaatc ctgaagatat
    11401 tgaattttat gatgaacaat tacaggcaga aaaggtggag gttttgaata ttcgattgga
    11461 agtaaaaaat tgaattatct acaatctcat caacaataaa cctatttcaa ccccattatc
    11521 tataggcgta tttttacgcc tttttatata cttgaagcac ataagaaaca ttatgggaag
    11581 tttgctgatg gaagtactca agaaattgat gttccttatg atattcctga tacttgggag
    11641 tgggtgagga taaaatcaat ttattggaat tttgggcaaa ataagccaga gaaatccttt
    11701 aggtatatag atacgtctag tattgataga aaaaagaaca taatcaacta caaaaatcta
    11761 caatatcttt cacctgaaca agcgccttcc cgtgctagaa aattagtttc gcagaatagt
    11821 gtcttatttt caacagttag accatatcta aaaaatattg ctgtagttag agaacttaaa
    11881 gagtatttga tagctagtac agcatttatt gttttggata ctttacttaa cgaaacatat
    11941 ttgaaatatt atttattatc agataatttt atcaatcgtg ttaataataa atctactgga
    12001 acaagttatc ctgcaatcaa tgattataat tttaatctat tattaattgc tctcccccca
    12061 ctatccgaac aacaacgaat a
//
LOCUS       DAVKMJ010000050        11872 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000050 DAVKMJ010000000
VERSION     DAVKMJ010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11872)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11872)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11872
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.050"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..674
                     /locus_tag="VW348_001771"
     CDS             <1..674
                     /locus_tag="VW348_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEU9746635.1"
                     /translation="KRIKRLRRISGGDTYTIIYLKLLLLSLKDEGKLYYDGVESDFIK
                     ELALTIDETDDDVMVTVNYLINQGLLEVVTENDEYYLTEIPNLIGSETAWAEKKRRYR
                     QNKQRTLSLMSPTHVRQEIEIEKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYK
                     NLKEKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYD
                     VGESL"
     gene            1358..1519
                     /locus_tag="VW348_001772"
     CDS             1358..1519
                     /locus_tag="VW348_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746636.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            1611..3290
                     /locus_tag="VW348_001773"
     CDS             1611..3290
                     /locus_tag="VW348_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU9746637.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGCIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIDLDNDEQVECVSLLEKRS"
     gene            3558..4124
                     /locus_tag="VW348_001774"
     CDS             3558..4124
                     /locus_tag="VW348_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746638.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            4446..4634
                     /locus_tag="VW348_001775"
     CDS             4446..4634
                     /locus_tag="VW348_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEU9746639.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            4696..5454
                     /locus_tag="VW348_001776"
     CDS             4696..5454
                     /locus_tag="VW348_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEU9746640.1"
                     /translation="MVVYIRQSKLPSEVSINKYHAQVGAYLQGEEAVLYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            5512..6366
                     /locus_tag="VW348_001777"
     CDS             5512..6366
                     /locus_tag="VW348_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEU9746641.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCNIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            6478..7362
                     /locus_tag="VW348_001778"
     CDS             6478..7362
                     /locus_tag="VW348_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEU9746642.1"
                     /translation="MKKVMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            7501..7602
                     /locus_tag="VW348_001779"
     CDS             7501..7602
                     /locus_tag="VW348_001779"
                     /inference="COORDINATES: protein motif:HMM:NF014902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
                     /protein_id="HEU9746643.1"
                     /translation="MNTLGDKLMELSAIYHRPESEYAYLYKDKKLHI"
     gene            7666..9264
                     /locus_tag="VW348_001780"
     CDS             7666..9264
                     /locus_tag="VW348_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
                     /protein_id="HEU9746644.1"
                     /translation="MEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTE
                     GQNILYGDKGCVENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFAN
                     GNALLNPEGTLDWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSN
                     HKYNTTDYFEIDRYFGDKETFRELVDQAHHRGMKVMMDAVFNHIGSQSLQWKNVVKNG
                     EQSAYKDWFHIQQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATY
                     WIEEFNIDAWRLDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHA
                     VMNYPLSDSIKDYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWT
                     ANEDVQLVKSALAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNF
                     MKRLIKIRKYASVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEA
                     VALASNCQELENQLVISPDGFVIF"
     gene            9539..9994
                     /locus_tag="VW348_001781"
     CDS             9539..9994
                     /locus_tag="VW348_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746645.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            10439..10915
                     /locus_tag="VW348_001782"
     CDS             10439..10915
                     /locus_tag="VW348_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9746646.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKERGANLLSRLYRYQDSQGI
                     SIDDESNPWILMSDDLSDLIQTNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            10915..11676
                     /locus_tag="VW348_001783"
     CDS             10915..11676
                     /locus_tag="VW348_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HEU9746647.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TKLSSLRYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPELSYLSTLIRYEE
                     LYIINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSSVYDSGENTT
                     SAADVLQELLFGEWSQVEKEMLQVGEKRLNELLEK"
BASE COUNT         4296 a         1637 c         2453 g         3486 t
ORIGIN      
        1 acaaaaggat aaaaaggtta aggagaatat ctggaggaga tacctatacg ataatctacc
       61 taaaacttct actactaagc ctaaaagatg agggcaaact ctattatgac ggagtagaaa
      121 gtgattttat aaaagagtta gcactaacca tagatgaaac agacgatgat gtaatggtaa
      181 cagtaaatta tttaatcaat caaggcttat tagaagttgt aacagaaaat gatgaatact
      241 acctaactga aataccaaac ttaatcggat cagaaacagc ctgggcagag aaaaaaagaa
      301 gatacagaca aaataaacag aggacattgt ccttaatgag tccaacccat gtccgacaag
      361 agatagagat agagaaagat atagagatag ataaagagag agagggagag atagataaaa
      421 agtccacccc cattttttat ggagaattca aaaatgtaag gttaagcaaa gaagaatata
      481 aaaatctaaa agaaaaatta aactcacaca cagatataat gataaataaa ctatccagat
      541 acatggaaag cagtggtaag acctatcaaa accactatgt gacaatctta aaatggtatg
      601 aagaagataa agacaaacta agacagaaag gtttaaataa aaaaatgaat tatgatgtag
      661 gagaatcttt atagataaaa agaggtggaa aggcactatt aaagacttta agtttaaaaa
      721 ggtatcaaag tatgccagag ataaaaaaat ataaatatga cactttaaag gcgattagaa
      781 aattaaagaa atgctagaag acttttagat gacagttacc aagagggtct aattttcact
      841 gctacttatg cagtaggaat tggacctttt tatataagca aattctattt caaaattggt
      901 taccaagaaa gacttctttt cactgttaag tataagaggg taatttatag aattttgtta
      961 catcaagata aatattttct gatggtcaaa ttttaaaaag attaataact ctcgataaat
     1021 tttgaacctt aacaattgaa tagaccaaga caagacgtta attatttttg gagcgtaata
     1081 acctatccgt caagatcttt cggctgaata attcggcaaa aaaagttctg ctaagcaaaa
     1141 agaaagtgag cgataagtaa gagtttgaat atagggaggg ataccctatc cgctatgaag
     1201 aaaatgagga taatgatact tctaaggttg aagccggctc atccggaata gaggcggagg
     1261 tgagattcct atgttgctaa tccaaagcac ttgtcaatgt caaaaaactt aattaaacaa
     1321 ataattatta gatataaaac tttagaggag gtatatattg gacaatgact ggaatggatt
     1381 ggctgattta atagcaaatc tgattgcaaa atatgctggt gctttagatt tagataatct
     1441 acccgatcca acgccagcaa aaaatcaaga gatgaaaaat agttttgaca tggcaaaaac
     1501 acaaattgag acggactaat aaaagtgtta taatatactt gaaatgatag tccaaactta
     1561 aattaaaaaa attatatatg atatagaaaa attatattga ggttaatact atgtcaaaag
     1621 aaaaaataaa agtatacctc tatacacgag tatctacgtc aatacagata gaggggtatt
     1681 cgttagaggc acaaaaatca cgaatgaaag cttttgctat ttacaacgat tatgaaattg
     1741 ttggagagta tgaagatgcc gggaagtctg gcaagtctat tgaaggtaga atacagttca
     1801 atcgaatgat ggaagatata aaatctggaa aagatggagt atcttttgtt cttgtgttta
     1861 agttatcaag atttgcaaga aatgccgctg atgttctttc tacacttcag ataatgcagg
     1921 attatggagt taatcttatc tgcgttgaag atggcattga ttcatctaaa gatgctggga
     1981 aactaatgat ttctgtttta tcagctgtgg ctgaaataga aagagaaaac atccgtattc
     2041 aaacaatgga aggttgcatt caaaaagcaa gggaaggaaa atggaatggt ggctttgctc
     2101 cgtatggata taaacttgaa gacggcaagc tgtttataaa tgaggaagag gcagttgcaa
     2161 taagaacgat tttcgaccag tatgtaaata ctacgatagg agccaatggg atatctaaat
     2221 acttagagaa tcatggaatt agaaaaatcc caagacagaa tggtaagaat cctttgtttg
     2281 atgcaggtct tataagaaag atattaaaga atcctgtata taatgggaaa atagcatttg
     2341 gaagaagaac tttagaaaaa gttcatggta caagaaatga atataagcag gttgaacaag
     2401 atgaatatct aatatctgaa gggatacatg aagctatagt ttccgatgaa gtttggcaag
     2461 ctgctcaggt taagctaaaa tctcaagcaa agaaatatga gcatgtgaat aaaggaaaag
     2521 atacacgcac acacttgctt tctggaattg taaaatgccc gatatgtgga gtgggaatgt
     2581 ttgggaacaa gtgtatcaag aaaaagaaag atggcacaaa gtataaagat ttttattact
     2641 atggttgtaa acataggcag atgataagag gtcataagtg tacattcagt aagcaaatta
     2701 gagaagaatt gttagatgat gctgttgcag aggtgattgt caagatagta agtaatccga
     2761 aatttgcttc tatgatgcaa gaaaaaatca acatgaaggt ggatacctct gaaatagaaa
     2821 aagaaataga taattaccaa aaggaattga gaaagagtca ttctacaaag tttaagctaa
     2881 ttgaggaaat agataattta gatgttgaag ataagcacta taagagaagg aaacaggatt
     2941 tagatgatag actatatcgt atgtatgaca aaatagatga attagaatca tcactaattg
     3001 atgcgaaagc aaagaaacag actattgaag ctgaaaaact tacaggagat aacatatata
     3061 aggttctgat ctattttgat aagctctata aagtcatgaa tgatgtagag cgtaggcagt
     3121 taatttcagc tttgatttct gaaattcaag tttatgaaga aaaacaatct aacggacaat
     3181 ggctaaaatc cattactttt aagctaccaa ttatagaaga aaatctcaac atagatttgg
     3241 acaatgatga acaagttgaa tgtgtaagtt tattagagaa acgtagttaa tcctcaaaag
     3301 gttccccaaa ctttttgagt cccactgacg catcacgctg aggcggtatc actgcttgta
     3361 cgagttgaag catcagcgaa gtaaaagtag atgttcagcc aatgcgacga ggtgagaccg
     3421 aaggtcgata aggtgtgttc tgggtatagg actcgtaaag taagtaggaa atatgatgag
     3481 atgatacaga gagcctgaat tggtcaggtg acgtgcttat ttacattagc ctgataatga
     3541 aaatggagag attatcgatg gttatattgg aattgtacca aaatgattat tctaaagatt
     3601 tagtagcatt tgattccata gaagatggga aagcctttgt ggctcaaatc ccgggataca
     3661 ctctggaaac agaagatggt tttgaagtgg agtattttaa tcctaaaaac ataccggatt
     3721 atatggaaat tatttttaac ggaaatattg ttcctttatc taaatttatg ttcgatcctg
     3781 aggaaaatgt aaacattatt tggaaagaga tttcaaattt atccctcaaa aatgatagag
     3841 tgatcgaagg atattcaaaa attgatgcat atgtcgttaa caaccatgaa gttaaagcct
     3901 atgtcgaaac aagagaaacg aactatcgta aagcaaaaga cttcttagaa agccgcggat
     3961 atgaaatcga cagaagcttt ttcggaagtg aagacggtga agcgattctt tacagaaaaa
     4021 aagggatcga agtttggcat ttcttgtgtc acttagaccc aatgtttgta gagattgaag
     4081 atgtagaagg atatgttaaa gaagaagttg gagagattca atagtcaacc aaagttcctt
     4141 gtgagtatat acctttgcta gtaaaagagt caaaacgtta taacgaaggg ggggaagaaa
     4201 acccttgagt gtaagtcttt ttcttgttta gagggaaagt attagagtag ccgctcataa
     4261 tttatactag atttgataac tgatttgaga cagattttat ttctataaat attgtgaaaa
     4321 ttttttaata ccaaagattt aaagttactg tgttaaaaat cctctccact tttaaactaa
     4381 tgtattataa aagccagttg acacaagtgt tacacctgtg atagaattaa cttgaggtga
     4441 tgaaaatggc aaccgataaa aatagaataa tgattagctt ggatgataaa aatctagaga
     4501 aacttgaaaa tttagtagaa gatgctagag atagaagggg aatgcgacta acaaagtccc
     4561 aggttattga attactccta aataccgttg attatttcga tgatattatg ggggctattt
     4621 actcaaaaaa ataagagcaa aattgctatt attttttaca aattggtgta acactagtga
     4681 tataggagtg atgaaatggt tgtttatatt agacaaagta aattaccaag tgaggtttca
     4741 attaataaat accatgctca agtaggtgcc tacttacaag gagaagaagc tgttttatat
     4801 caatcttttt ctgaaataaa agagttaaca agtgaagata tagttgtaga ttatataatg
     4861 gagactagag cattactaaa aatgatgggc ttaaacgttc cggttcatga ctatcctatt
     4921 gagcttaaag agttttatgg tcgaaagatt tatgctggta ttttaggaga gattgtgaat
     4981 atacctgata attggggaaa atttattaag cctaaagctg gttcaaaagt ctttactgga
     5041 agagttgtta atggaaccca tgatttaata ggtattggtc tacctttcga ctatcctata
     5101 tggattagtg aggttgtaga attcatagct gaatggcgtt gttttgtgtt agatggtcgc
     5161 gtattagatg ttcgacccta tacaggtgat tatcatgcac aatttgatgc aagtgtaatt
     5221 gatgaagcga tatcatgttg gaaagatgcg ccaatagctt atggactaga tatcggtgtt
     5281 actcgcgatg gcagaacact tgttgttgaa gtaaatgatg gttatgcatt gggaaattat
     5341 ggcctatctc ctttaaaatc aatcaatttt catagagcta ggtggaaaga aatggtaaaa
     5401 ccctattttg aaaaaaatga aatttttaaa atccaacagg atgttgtttt ctaaaataaa
     5461 tatggtatat aaccaatata aaaagcatca aaatgaacaa ggaggaatct gatgcttgga
     5521 gcaattattg gagatattgt cggttctgtt tacgaatgga acaatatcaa aacaaaggac
     5581 tttcctttat ttcggaagga ctgctttttt acagatgaca cggttatgac ctgtgctgtt
     5641 gcagaagcaa ttatgaatgg tggacaaaaa gacgatttca ttgacgcgat gaagaaatat
     5701 ggcagaatgt atccgaatgc tgattacggt gctcggttta atgcatggct aaacagcgat
     5761 aaccgtgagc cttataatag ctttgggaat ggatcagcta tgcgtatttc tccatgtgct
     5821 tggatcatgg actgtggttt ttatgcgaaa actggtatgt ggccatcatc tagaggactt
     5881 acgagtcttt ctgcagaggt aactcataat catccagaag gtgtcaaagg cgctatggct
     5941 acagctgatg ctatctttct atgtcgtttt tactttggtg gttattgtag agagtacgag
     6001 caatcaatta acgacaatcc tacagagtgt aaaagacgaa ttaaggatta tatagaaaaa
     6061 gaatacgatt acaatctatc tcaaacttta gatgaaatcc gtcctaacta tcgttttaac
     6121 gaaacatgtc aggaaactgt ccctcaagcc attatcgcct ttcttgaaag tagagacttc
     6181 gaagatgcga taagaaatgc catctcactt ggtggcgaca gtgatactct cgcagcaatc
     6241 acttgtaaca tagcagaggc agcttacggt attcctgatt ggatcaagga taaggcctat
     6301 tcttacttgg atgaaccctt aaaggatgta gttaggcgat gggaaaatag aataaaagcg
     6361 tattaatctc cagtacgtca gatttctctt ttctgtattt tcattgtata ataggattac
     6421 atttacttgc atacgacgaa atgtaaacat ttctgtttaa aattaaggat aaaatcaatg
     6481 aaaaaagtaa tggtaattat caaccctact tctggtggcg agaaggcttt ggattacaaa
     6541 gaaaagctgg agaataaagc aaaagaatac tttgaatatg ttgaaaccaa aattaccgaa
     6601 aaagcgctgg atgcaacaca ttttgctgaa gaagcttctc gtgagcagta tgatgcagtg
     6661 gttgtgtttg gtggagatgg aactgtcaat gaagtcattt caggtattga tgagagagac
     6721 tacattccta agttagggat tatcccaggc ggtacgggta acctcattac aaaacttttg
     6781 gaaatcaatc aagacatcga tggcgcaatt gacgaactgg attttgattt aaccaataag
     6841 attgatatcg gtaaagcaaa tgacaactat tttggttata tctttagtat cggttctctg
     6901 cctgaggcga ttcacaatgt tgaaatagag gacaaaacaa aattcggtat tttaacctat
     6961 gctgtaaata ccatgaagtc tgtcatgaca gatcaggtct ttaacattaa ggttgagaca
     7021 gaaaatggaa attatgttgg tgaagctagc catgttttgg tccttttgac aaattacttc
     7081 gctgataaga aaatctttga agaaaacaag gacggctatg ccaacatttt gattctgaaa
     7141 gatgcctcta tattctccaa attatccgtc attcctgatt tattaaaagg ggatgttgtc
     7201 gcaaatgata atatcgagta tatcaaagcg cgtaatatta aaatctcttc agatagtgaa
     7261 ttggagtcag atgttgacgg agataaatca gataacctac ctgtagaaat caaagtccta
     7321 gctcagcgag tagaagtatt ttcaaaaccg aaagaggatt agtatataga gaaagccttt
     7381 tttaaggctt tttgtatact ttaaaagata gttcctttaa caacggacat tccttgcaaa
     7441 tagtttacaa aaatagtata ctggatttat tgagtttgaa aacgtttgcg taaaatttga
     7501 atgaatactt taggagacaa attgatggaa ttgagtgcta tttaccatag gcctgagtcg
     7561 gagtatgcct atctttataa ggataagaaa ctccatattt gaattcgaac taagaaaggg
     7621 gacattgaaa gcatcaactt gcactatggg gaccctttta tctttatgga ggagttttat
     7681 caggatacaa aagaaatggt caagataact tctggtacct tatttgacca ttggcaggtt
     7741 gaagtgtcag ttgactttgc acgtatccag tatctctttg agctcagaga tacagaaggt
     7801 caaaatattt tgtatggcga taaagggtgt gtggaaaatt ctctagaaaa tcttcatgca
     7861 attgggaatg gatttaagtt gccttatctt catgagattg atgcctgcaa ggttcctgac
     7921 tgggtttcaa atacggtatg gtatcagata tttcctgaaa gatttgccaa tggcaatgct
     7981 ctattaaacc cagaagggac tttagactgg gattcatctg tcacacctaa gagcgatgat
     8041 ttctttggtg gtgatttaca ggggattatt gatcatatgg attacttgca agacttgggt
     8101 attactggac tatatctttg tcccatcttt gaatctacaa gcaatcacaa gtacaatacg
     8161 acagattact ttgaaattga ccgttatttt ggagacaagg agacctttcg ggaactggtg
     8221 gatcaagcgc atcatcgtgg catgaaagtc atgatggatg cggtatttaa tcatattggt
     8281 tcgcaatctc ttcaatggaa aaatgtcgtc aaaaatggcg aacagtctgc ttataaggat
     8341 tggttccata ttcaacaatt cccagtgaca actgaaaagc tagttaataa gagagactta
     8401 ccctatcatg tttttggttt cgaggactat atgcctaagc taaatacagc caatccagag
     8461 gtcaagaatt atcttttaaa ggttgcgact tattggattg aagagtttaa tatcgatgct
     8521 tggcgtttgg atgtggctaa tgagattgac catcagttct ggaaggattt tcgtaaggca
     8581 gttttagcta aaaatcctga tctttatatc ctaggagaag tctggcatac atctcagcct
     8641 tggctaaatg gagatgagtt ccatgccgtc atgaattatc ctttatctga tagtatcaag
     8701 gactatttct tacgaggaat taagaagaca gaccagttca tcgatgaaat caatggagag
     8761 tctatgtatt acaagcagca gatttcagag gtcatgttta atctcttgga ttcacatgat
     8821 acagagcgaa tcctgtggac ggccaatgaa gatgttcaac tggttaaatc agccttagcc
     8881 tttctctttt tacaaaaagg aacaccgtgc atttattacg gaaccgagct agccttgact
     8941 ggaggaccag atccagattg tcgtcgttgt atgccttggg aacgtgtatc aagtgacaat
     9001 gatatgctga actttatgaa gaggctgatt aagattcgga aatacgcgtc agtaatcatt
     9061 tcgcatggca agtatagcct tcaagaaatc aaatctgatc tagtagctct ggaatggaaa
     9121 tacgaaggac ggatcctcaa agcaatattc aaccaatcaa cagaagatta tcttttagag
     9181 aaagaagcag tagcactagc aagcaattgc caagaattgg agaatcagct tgtcatctct
     9241 ccagatggat ttgtgatttt ctaaaaacta gttgatgaag attatggtac atttcatatc
     9301 ttatatagta taataaggct agttactaaa cttgtaaagg agaacttaaa tgaattgtag
     9361 aggacatgaa acaagacaaa gaattgttag agattttgaa gtttagccta aagcacatat
     9421 taagctgtta gcaaatcaac aaaaacatag tgatgcagga gcaactattg aagatgaata
     9481 ttatgtattt atcgctgaga gtaaaattga tggcaagaag gaagttattc agtgttgcat
     9541 gggtgcggca agggattttt tagaactaat taatcacaaa gggctacctc tttttaatcc
     9601 gcttgtaggt gattctcatg taaataatag acaagaatat gacaatacag ggagtggaaa
     9661 tttacaacct gaaaagtgga atgaaactgc aaagcagctt tataatgcta taatgtggtt
     9721 gattatttta tggaatgcta agccggatac acctttattt aattttaaag acgaagtaat
     9781 taagtataaa acatatgagc cttttgaaag cagtataaaa agagtaaata ctactataaa
     9841 gaatggtagt aaagggaaaa ctctgactga gatgattaat ggctacagag cggataacga
     9901 tattagagat gaaatttgta actttaatat tctgaaaaat aaaattcgtg atatgaaaga
     9961 ccaacaagga aatacaatgg aatcttactt ttagttattg ttgaattttg ggtattctat
    10021 aaaatatcct aattgagatt taaatagtag actatacaat atagttaaaa tatcagtaaa
    10081 aacaacactt tattgaggta ttggatacgc tttgctaata gcctaataat cacatgtgga
    10141 gtgttgctac aacgaaaaag gtgataatcc ttaatttcaa gctattttat aagcattttg
    10201 tctttgtaga taaaggcaat tttgacaata aaaatcctaa aaggtgaatc gttatagatg
    10261 tatttgtaga tattgtttgc gcatcgaaaa aattaataca agaataaata tttatagctc
    10321 tttaggtgac ttttatagaa gtaaagttta ggatagaaaa acaagaaata acgcaccatt
    10381 tttggtgcgt tatgcttttt tatgctataa tggatttata aaaataaagg agtttgctat
    10441 gattggaaag aacataaaat ccttacgtaa aacacatgac ttaacacaac ccgaatttgc
    10501 acgaattata ggaatttctc gaaatagtct gagtcgttat gaaaatggaa cgagttcagt
    10561 ctctaccgaa ttaatagaca tcatttgtca gaagtttaat gtatcttatg tcgatatcgt
    10621 aggagaagat aaaatgctca atcctgttga agattatgaa ttgactttga aaattgaaat
    10681 tgtgaaagaa agaggtgcta atctattatc tcgactctat cgttatcaag atagtcaggg
    10741 aattagcatt gatgatgaat ctaatccttg gattttaatg agtgatgatc tatctgactt
    10801 gattcagaca aatatctatt tagtagaaaa ttttgatgaa atagagagat atagcggcta
    10861 tttggatgga attgaacgta tgttagagat atctgaaaag cggatggtag cttaatggaa
    10921 atccaagatt atactgatag tgaattcaaa catgctttag caaggaatct tcgttcactg
    10981 acaagaggaa aaaagtccag taaacaacct atagcgattt tgcttggagg tcaaagtggt
    11041 gccggtaaga ctacaattca tcgtattaaa cagaaagaat ttcaaggaaa tattgttatc
    11101 atagatggtg atagttttcg ttctcagcat ccacactatt tagaactgca gcaagaatat
    11161 ggcaaagaca gtgtagaata taccaaagat tttgcaggaa aaatggtaga gtctttagta
    11221 acaaaattga gtagtttgag atacaatctt ttgatcgagg gaactttacg aacagttgat
    11281 gttccaaaga aaacagcaca actcttgaaa aataagggat atgaagtaca attggcctta
    11341 attgcgacaa agcctgaatt gtcgtatcta agtactctta tccgttatga agaactgtac
    11401 attatcaatc caaatcaagc acgcgcaact ccaaaagaac atcatgattt cattgtaaat
    11461 catctagttg ataatacacg acaattggaa gaactggcta tctttgaaag aattcaaatt
    11521 tatcaacgag atagaagttc tgtatatgat tcaggagaaa atacaacttc agcagcagat
    11581 gttcttcaag agttactgtt tggggagtgg agtcaggtag agaaggagat gttgcaggtg
    11641 ggggaaaaga gacttaatga attacttgaa aaataaacaa ttgatatttt taggagagta
    11701 gaaatgagag ggtttaataa caagataaag tctgtttatc aagaactaac aaattccaaa
    11761 gagaaattcg gtagctttca caagacttta attcatttgc atacacctgt ttcttatgat
    11821 tacaagctat tttctaattg gactgcaacg aaatatagaa aaattactga ag
//
LOCUS       DAVKMJ010000051        11799 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000051 DAVKMJ010000000
VERSION     DAVKMJ010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11799
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.051"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            96..656
                     /locus_tag="VW348_001784"
     CDS             96..656
                     /locus_tag="VW348_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEU9746648.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            657..2042
                     /locus_tag="VW348_001785"
     CDS             657..2042
                     /locus_tag="VW348_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9746649.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQVI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILFQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            2044..2694
                     /locus_tag="VW348_001786"
     CDS             2044..2694
                     /locus_tag="VW348_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEU9746650.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            2705..3397
                     /gene="tenA"
                     /locus_tag="VW348_001787"
     CDS             2705..3397
                     /gene="tenA"
                     /locus_tag="VW348_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEU9746651.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKEMEISDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            3402..3926
                     /gene="thiW"
                     /locus_tag="VW348_001788"
     CDS             3402..3926
                     /gene="thiW"
                     /locus_tag="VW348_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEU9746652.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            3926..4729
                     /locus_tag="VW348_001789"
     CDS             3926..4729
                     /locus_tag="VW348_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEU9746653.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLNYRPTVIKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSKNQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEAYE"
     gene            4722..5354
                     /locus_tag="VW348_001790"
     CDS             4722..5354
                     /locus_tag="VW348_001790"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEU9746654.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(5563..6354)
                     /gene="thiD"
                     /locus_tag="VW348_001791"
     CDS             complement(5563..6354)
                     /gene="thiD"
                     /locus_tag="VW348_001791"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEU9746655.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQAKDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSNARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEDMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(6438..6536)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6720..7115
                     /locus_tag="VW348_001792"
     CDS             6720..7115
                     /locus_tag="VW348_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEU9746656.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTVQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            7126..7497
                     /locus_tag="VW348_001793"
     CDS             7126..7497
                     /locus_tag="VW348_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEU9746657.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHTNLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            7507..9750
                     /locus_tag="VW348_001794"
     CDS             7507..9750
                     /locus_tag="VW348_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEU9746658.1"
                     /translation="MTEIVKASLENGIQKIRIRSEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYTVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDVIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQTLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            9957..11732
                     /gene="spxB"
                     /locus_tag="VW348_001795"
     CDS             9957..11732
                     /gene="spxB"
                     /locus_tag="VW348_001795"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEU9746659.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
BASE COUNT         3343 a         2302 c         2636 g         3518 t
ORIGIN      
        1 attcctgtgt actgttctaa attcaatctg ctatacaaag tatttaggtc ggtcttcttg
       61 agtgccccac ttttctttta aaaaaggagt tttttatgtt gaaaaaatgg cagttaaaag
      121 atgttatctt gcttgctttc ttgtctatct tttttggtgg ggttttcgtt ggttcaggat
      181 atgtgtataa tattctcagt ctactcttaa cacctcttgg tttgcaggcc tttgccaatg
      241 aaatcctctt cggtctctgg tgtatggctg cgcccattgc tgccatcttt gttccgagag
      301 tcggaagtgc aacgattgga gaagtgctag ctgcgcttgc tgaagtcctt tatggtagcc
      361 aatttggtct aggagctctt ttgtctggct tggttcaagg tttgggaagt gaatttggtt
      421 ttatcgtaac taagaatcgc tatgaaagtt ggctctctct aactgctaat agtattggga
      481 ttacgcttgt tagctttgtc tatgaataca ttaagttagg ttactacgcc ttttcccttc
      541 cgtttgtcct ttccttactt gtggtacgtt ttatttctgt ttatttcttc tgtaccatct
      601 tggttcgtgc cattgtcaaa ctctatcatc agtttgcaac tggaggaaaa gcatagatgg
      661 gtctggaact acgagcgatt cagtccccaa tcttctctga gccgtttgat tttacttttc
      721 atgcgcaagc ctttaccttg ttagttggga gcagtggttc aggaaaatcc agcctttttc
      781 aagtcattgc ccaagtcagt tctcttccct atagtggtca agtcctgata gatgggagcg
      841 aggtcagtca gctttctatc atcgcacgtg tccagaaggt tggcattctc tttcaaaatc
      901 ccaatcatca atttaccatg gagaacttgt ttgaggagct gattttcacc ttggagaata
      961 tcggctatca ccttcaggaa attgattcta aaatagcaga ggttgtccag caatgtcgtt
     1021 gcgaggcaat cttacaccgt cccattcatc acctatcagg tggggaaaag caaaaagcag
     1081 cgctggctgt cctctttgcc atgaatccta gggtctatct cttggatgag cccttcgctt
     1141 ctattgaccg caagagcaga atcgagatat tggagattct aaaagagttg gctcttgatg
     1201 ggaagacagt tattttgtgc gaccatgatt tatctgacta taaagcctat atcgaccata
     1261 tggttgagct aagagacgga aaactaaggg aagtgtttca aatcccttcc tatgagatga
     1321 cacaggttgc ttcaaaggaa gttgcttcta gcccggaact attccatatg aaccgtgtga
     1381 ctggtgagct tggtaatcgc cccctctttt caattgctga tttcacattc tatcaaggga
     1441 tttcctgtat cctgggtgac aatggtgtcg ggaaatcaac cctctttcgc tctattcttc
     1501 aatttcaaaa gtataagggg cgcattgcat ggaaggggac agtcctgaaa aagaaaaaga
     1561 gtttgtatcg tgatctgact ggtgttgttc aggaagctga gaagcagttt atccgagtca
     1621 gtctgcgaga ggagcttcaa ttagatggac ctgattctga aagaaatcag cggatttttc
     1681 aagctttacg atattttgat ttggagcagg cagtcgataa gagtccctat caattaagtg
     1741 gtggtcagca aaaaattctt cagctcttga ccatcttgac cagtaaggct tccgtgatct
     1801 tgctagatga accttttgca ggtttggatg atagagcctg ccattatttt tgcaagtgga
     1861 ttgtggagga gaggaatcaa ggaagaagtt ttctgctcat tagtcatcgt ttagaccctt
     1921 tgatttctgt ggttgattat tggattgaga tgactagtca gggtcttcgg catgtgaaag
     1981 aagtgaccat taccaaacca cttacatctc agagtagcaa tacccaaggg gaggtgagat
     2041 agtatggtca aagtagcaac ccagacaccg attatcagtc tcttcttgct gattttatcc
     2101 ttggaaacat ctttcattcc ttcgattgct ctgaatcttt cggtagtcgc attttgtatt
     2161 ctctttatgc tctattaccg tcgatttaaa atgttagctt ggatgatcat acttgccatt
     2221 ttaccatctt ttgccaacta ctgggcagtt cagttacacg gagatgcttc acaggcagtc
     2281 atgcttggaa cgagggcctt tgtgacagtt tgtatcggcc ttgtctttgt ttcctctatt
     2341 tcactaaaag agcttctctt gtacttggct caaaaggggc tatcacgctc ttggtcctat
     2401 gccttgattg tggtattcaa ttcctttcct ctcattcagc aagaaatcaa gtccctcaaa
     2461 gaagcttgcc tattacgtgg tcaagaactg catttttggt cgcccttgat ttacagtaag
     2521 gttctgatga cagtctttag gtggcgccat ctttacctga gagctctgtc tgctcatgga
     2581 tatgacgaac atgcacagtt gaagaatagc tatcggactt tttatattcc taaaaaaaca
     2641 aaattaatct acctgctttt ctttttattg cttcaaacca gtctattttt ataaaggagt
     2701 tattatggaa tttacagata ttgcgatgga attatccaag aaagcttggc aggcttcctt
     2761 tcatcatccc tttattttac aattacaaga ggggaattta gaacctgcca ttttccgcta
     2821 ttacctgatt caggatgcct actatctgaa ggccttctca gaaatctatc atcttttggc
     2881 tgataagact tcaaaccaag agatgaaaag actcttgaaa caaaatgctc agggtttagt
     2941 ggagggtgag ttatttattc gccaacaatt tttcaaggaa atggaaatca gcgaccagga
     3001 aatggagcaa catccaattg ctccaacctg ttatcattac atttctcata tttataggca
     3061 atttgcagaa ccgaacttag ccatagcttt tgcaagcttg cttccttgtc cttggttata
     3121 ccatgatata ggcaaatcac ttaatcttaa accatcacca aatcctctct atcaacaatg
     3181 gattgaaact tatattacgg atgagttaga gcaacagatc agagaggagg gagcactggt
     3241 caatcagctc tatcgagaaa gtgatgagac agataagcaa aaaatgctag atgccttcca
     3301 catcagtgtt catatggaag ccaagttttg ggagatggct taccaacacc agacatggaa
     3361 gagcgattta cagtctttag aaaaaggaga agaatagaaa catgagaaag caccaactac
     3421 aagttcacaa attgaccatt ttatctatga tgattgccct tgatgtagtc cttacaccta
     3481 tctttcgaat tgagggaatg gcaccgatgt ccagtgtagt caatattcta gcgggaatca
     3541 tgatgggacc tgtttatgcc ttggccatgg ctacagtcac agcctttatc cgtatgacga
     3601 ctcaagggat tccgccttta gctctcacag gagcgacttt tggagccctt ctggcaggtc
     3661 tcttttataa gtacggtcga aaattttatt tttctgcctt gggagaaatt gtgggaacag
     3721 gtattattgg ttccattgtt tcctatcctg ttatggtact ctttacagga tcagctgcta
     3781 agcttagctg gtttatctac acgcctcgat ttttcggagc aaccttgatt ggtacagcga
     3841 tttcctttat tgcctttcga tttttaatca agcaggaatt ctttaaaaaa gtgcagggat
     3901 atttctttag tgaaaggata gactgatgca ggaatttaca aatccctttc ctataggctc
     3961 tagttcccta attcactgta tgaccaatga gatttcttgt gagatgctgg caaatgggat
     4021 tttggctctg ggatgcaaac ctgtcatggc agatgatccc cgtgaggttc ttgattttac
     4081 taagcaaagt caggctcttt tcatcaattt ggggcatttg tcagctgaga aggaaaaagc
     4141 aatccgcatg gcagcttcgt atgcaaacca atcttctctc ccgatggtag tagatgcggt
     4201 tggcgtaacg acttcatcca ttcgtaagag cttagttaaa gaccttttaa actatagacc
     4261 tacggtcatt aaaggaaaca tgtcagaaat tcgaagtctt gttggcttaa agcaccacgg
     4321 cgttggggtc gatgcgagtg ctaaagatca agaaacggag gatttgcttc aagtcttgaa
     4381 agactggtgt cagacctatc ctggtatgtc attcttagtt actggcccca aggacctcat
     4441 cgtttcgaaa aatcaggtcg ctgtactgga gaatggctgt actgaattag actggataac
     4501 agggacagga gatttggttg gagccttaac agccgttttt ctcagccaag gaaagactgg
     4561 ttttgaagct tcttgcttag cagtctctta tctcaatatc gctgctgaga aaatagttgt
     4621 tcaaggaatg ggattggaag aatttcgtta ccaagtactc aatcagcttt cgctcctaag
     4681 aagagatgaa aattggctag ataccatcaa aggagaggct tatgaataga gaagcactta
     4741 gactatatct ggtaaccaat cgctatcaag attccgtgga aagctttctt gcaaaagttg
     4801 agacggcctg ccgttcaggg gttaccatag tccaattgcg agaaaaaaat ctcacaacca
     4861 atcaatatta tcaactggca aaacaagtca aggaaataac agatgcctat caggtaccct
     4921 tgataatcga tgatcggttg gatgtttgtc ttgcggttga tgctgctggt ctgcatattg
     4981 gagatgacga actcccagtt tcggttgccc gacaagtctt gggtcctgaa aaaatcctcg
     5041 gtgtcaccgc taaaacggtt aaaagagctc tggaagcgga gaaatcaggt gcagattact
     5101 tggggacagg agccattttt ccgacaacca ccaaggaaaa tgcacccatc accctgattt
     5161 caaccttgaa aacaatttgc caaacggttg ccattccaat agttgctatt ggcggcttga
     5221 cttcggagaa tattgatcag cttatgggca ctggcatagc tggtgtagct gttgtacgtg
     5281 atttgatgca agcagaagat attgaggcaa aaacgcaagc ctttttaaca aagttgcatg
     5341 acattctttc ctaattaata ctcaatgaaa atcaaagagt aaactagaaa gctagtcgca
     5401 ggttgctcaa agtactgcct tgaggtttta gataagactg acgaagtcag ctcaaaacag
     5461 tgttttgagg ttgcagatgg aagctgacgt agtttgaaga gattttcgaa gggtataaaa
     5521 actctctaat tcccttaaag tgggaactag agagtttttt tcttaatctt taaaagttgt
     5581 atggttgact ggaccagaac catgaccgag ttgaggggca tcttgaatag cttttgtgat
     5641 aaaggccttg gccttatcaa ctgcctggta aagactcttg cccttggcta gttcagcagt
     5701 aatcactgca gcaaaggtac atccagtacc atgggtgtga caggtttgaa ttcgtgggct
     5761 ttcccagaca aattgttcat tcttggtaaa gaggaaatct ttagcaccac ctttgagatg
     5821 tccgcctttg ataaccacag actgaggacc aaattctttt aaaatcaggc gaccagcacg
     5881 ctgcatgtct tcggggtcat ggattgaaaa accaacaatc tcttctgctt caggaagatt
     5941 tggcgtaata atagttgcta gaggtagtaa gtttgttttg agatagtctc tagcatttga
     6001 gtcaatcaag gcatctccac ttgtagcaac cataacagga tcaaggacat agggacaatc
     6061 cagtttttta agatagggtt ggatgatttc catgatttca gtagtagcca acattccagt
     6121 ttttacagcc tgaggtggaa tatcagaaaa gacactctcc aattgggctt tcaacatttg
     6181 aggagaaacg tgctcgatta gctgaacacc tctggtattt tgagcgacaa gactggttac
     6241 aacagccatt ccatagacat ctttcgcttg gaatgacttt aaatctgcca taatgccagc
     6301 accaccacta gggtcagtcc ctgcaatggt caaagcaacg ggtaaataag tcatctaaaa
     6361 cctcccaacc aactgaagtt tgtattctta agaacaagct agtctgtttt agaaaggcaa
     6421 tagaagactg ctagtcccca ttatcatttc cacttccatc agctagcatt acctagattg
     6481 agtcagaggg atctaacagt cgttaatctc agctttacgc acccctagtg gttgttttct
     6541 tttttcttta gtatagcata tttttattgt ttatatagta atatttgact gcaaatcgtt
     6601 tttcaaatga ttaaaattct atttttcgaa gaaaatatta tttctataat tgacaaatgt
     6661 agattttaag agtatactga tgagtgtaat tgacaaatgt agattttgga ggtatggtaa
     6721 tgcagatttc agatgcagaa tggcaggtca tgaagattat ttggatgcag ggggagcaga
     6781 ccagtacaga tttgattagg gttttggcag agcggtttga ctggtccaag tccacggttc
     6841 agacactttt ggctcgtctg gttgagaaag agtgtttgac tcggaaaaaa gaaggcaagt
     6901 cctttgttta ttcagccctt ttaactctag accaaagtcg ggatttactt gtccaagata
     6961 tcaaagacaa ggtttgttcc cgtaggatta ggaatttgtt ggctgacttg attgtagaat
     7021 gtgaatttac tcagactgac ttggaagact tggaagctgt gatttcagag aagaaatcaa
     7081 gtgctgtaac agaagtaaga tgtaattgta tgtaaaggag acgtcatgtt aaatagtatt
     7141 gtaaccatta tttgtattgc ccttatcgcg tttatcttgt tttggttttt caaaaagcct
     7201 gaaaaatctg gacaaaaagc ccagcaaaaa aacggatacc aagagattcg agtggaagtc
     7261 atgggaggct atactcctga gttgattgtc ctcaagaaat cagtgccagc ccgcattgtc
     7321 tttgaccgca aggatccttc accatgtctg gatcaaattg tttttccaga ttttggtgta
     7381 catacgaacc tgccaatggg ggaagagtat gtagtggaaa tcacgcctga acaggctgga
     7441 gaatttggct ttgcttgtgg tatgaacatg atgcacggca agatgattgt agagtaggtg
     7501 gagactatga cagaaattgt gaaagcaagc ttagaaaatg gcattcaaaa aatccgtatc
     7561 cgatctgaaa aaggctatca tccagcccat atccagcttc aaaagggaat tccagctgag
     7621 attacctttc atcgtgctac tccttcaaac tgttataagg aaattctgtt tgaagaagaa
     7681 ggtatcttgg aaccaatcgg cgtagatgag gagaaagtca ttcgttttac acctcaagaa
     7741 ttagggcgac atgaattttc ttgtggcatg aagatgcaaa agggaagcta tacagtcgtt
     7801 gagaagactc gaaaatctct atctctcctg caacgttttt ggattactag tatctttact
     7861 gtgcctcttg tgattctcat gattgggatg ttgacaggta gcattagtca tcaagtcatg
     7921 cattggggaa cctttctagc aacaacgcct attatgttag ttgcaggtaa gccatatatc
     7981 cagagtgctt gggccagttt taaaaagcac aatgccaaca tggatacctt ggttgcgctg
     8041 ggaactctag tggcttattt ctatagccta gttgctctct ttgctggtct ccctgtttac
     8101 ttcgaaagtg ctggatttat cctctttttc gttcttttgg gagcagtttt tgaggaaaaa
     8161 atgagaaaaa atacgtccca agctgtggag aaattactgg acttgcaagc taaaaccgca
     8221 gaagtcttga gtgatgatag ttatgtccaa gttcctttgg aacaagtcaa ggtaggcgac
     8281 ctgattcgag tgcgtcccgg tgaaaagatt gctgttgatg gtgtcgtagt agaaggtgtc
     8341 tctagtattg acgaatccat ggtgacaggt gagagtctgc ctgtggacaa gacagttgga
     8401 gatactgtca ttggctcaac catcaatcat agtggaacgc ttgtctttag agcagaaaaa
     8461 gttggctcag agactgtttt ggctcagatt gtggattttg tgaagaaagc tcagacaagt
     8521 cgtgcgccga ttcaggactt gacggataag atttcaggga tttttgtccc agtagttgtc
     8581 attttaggaa tcatgacctt ttgggtttgg ttcgtcttgc tcagggatag tgtggttgtg
     8641 cttggagcta gctttgtgtc ctctcttctc tacggagtgg cggttttgat tatcgcctgt
     8701 ccttgtgcct tgggacttgc aacaccgaca gcccttatgg tggggacagg acgtagtgcc
     8761 aagatggggg ttctcctcaa aaatggaact gtcttacagg aaatccagaa agttcaaacc
     8821 cttgtctttg ataagaccgg gactttgacg gaagggaaac ctgtggtaac agatgtcatc
     8881 ggcgacgaag tagaagtgtt tgggttggca gcctccttgg aagatgcttc tcaacaccca
     8941 ctggctgagg ctatcgttaa gcgagcgagt gaagctggac ttgagtttca aactgttgaa
     9001 aattttcaga ccttgcacgg gaaaggtgtt tcagggcgaa tcaatggaaa acaagtttta
     9061 cttggaaatg ctaaaatgct ggatggcatg gatatttcta atacttatca agataaacta
     9121 gaagaactag aaaaagaagc taagacagtt gtgttcttag ctgttgacaa tgaaatcaaa
     9181 ggcttgcttg ctttgcaaga tattcctaag gaaaatgcta agctagccat cagtcagcta
     9241 aaaaaacgtg gtctccgaac agtcatgctg acaggagaca atgctggtgt ggcgcgtgct
     9301 attgcagatc aaatcggaat tgaagaggtc attgcaggcg tcttgccaga agaaaaagcc
     9361 catgaaatcc ataaactgca acagtcaggg aaagtagcct ttgttgggga cggtatcaat
     9421 gacgctcctg cccttagtgt agcagatgtg ggaattgcta tgggtgctgg aacagatatc
     9481 gccatcgagt cagcagattt ggtgttgaca accaataatc ttttaggagt ggttcgtgcc
     9541 tttgatatga gtaagaaaac ctttcatcga attctactca atcttttctg ggcttttatc
     9601 tacaatgttg tcggaattcc gattgcagca ggagtctttt caggtgttgg actggctctc
     9661 aacccagaat tggcaggtct agccatggcc tttagttctg tatctgttct gaccagttcc
     9721 cttctgttaa attttagtaa aatagactaa aagtaatgac tagatttctt tgttataaaa
     9781 cagaaacgac aacactttca aaactgtatt agaatagaga atagagagtt ttgagcagat
     9841 ttttagaaaa gtcagcataa atatgataca gtggaatagt aaaaatttgg agaacgtttc
     9901 caattctatg taatcgtatt ctccaagttt aaaaaaattg aaggagagtt atcattatga
     9961 ctcaagggaa aattactgca tctgcagcaa tgcttaacgt attgaaaaca tggggcgtag
    10021 atacaatcta cggtatccca tcaggaacac tcagctcatt gatggatgct ttggctgaag
    10081 acaaagatat ccgtttctta caagttcgcc acgaagagac aggtgctctt gcagcggtta
    10141 tgcaagctaa attcggcggc tcaatcgggg ttgcagttgg ttcaggtggt ccaggtgcga
    10201 ctcacttgat taacggtgtt tacgatgcag ctatggataa cactccattc ctagcgatcc
    10261 ttggatcacg tccagttaac gaattgaaca tggatgcttt ccaagagctt aatcaaaacc
    10321 caatgtacaa cggtatcgct gtttacaaca aacgtgtagc ttacgctgag caattgccaa
    10381 aagtaattga cgaagcctgc cgtgctgcag tttctaaaaa aggtccagct gttgttgaaa
    10441 ttccagtaaa cttcggtttc caagaaatcg atgaaaactc atactacggt tcaggttcat
    10501 acgaacgctc attcatcgct cctgctttga acgaagttga aatcgacaaa gctgttgaaa
    10561 tcttgaacaa tgctgaacgc ccagttatct atgctggatt tggtggtgtt aaagctggtg
    10621 aagtgattac tgaattgtca cgtaaaatca aagcaccaat catcacaact ggtaaaaact
    10681 ttgaagcttt cgaatggaac tatgaaggtt tgacaggttc tgcttaccgt gttggttgga
    10741 aaccagccaa cgaagtggtc tttgaagcag acacagttct tttccttggt tcaaacttcc
    10801 cattcgctga agtttacgaa gcattcaaga acactgaaaa atttatccaa gtcgatatcg
    10861 acccttacaa acttggtaaa cgtcatgctc ttgacgcttc aatccttggt gatgctggtc
    10921 aagcagctaa agctatcctt gacaaagtaa acccagttga atcaactcca tggtggcgtg
    10981 caaacgttaa gaacaaccaa aactggcgtg attacatgaa caaactcgaa ggtaaaactg
    11041 agggtgaatt gcaattgtat caagtttaca atgcaatcaa caaacatgct gatcaagacg
    11101 ctatctactc aatcgacgta ggtaacacta ctcaaacatc tactcgtcac cttcacatga
    11161 cacctaagaa catgtggcgt acatctccac tctttgcgac aatgggtatt gcccttcctg
    11221 gtggtatcgc tgctaagaaa gacaatccag atcgccaagt atggaacatc atgggtgacg
    11281 gagcattcaa catgtgctac ccagacgtta tcacaaacgt tcaatacgac cttccagtta
    11341 tcaaccttgt cttctcaaat gctgagtacg gcttcatcaa gaacaaatac gaagatacaa
    11401 acaaacactt gtttggtgta gacttcacaa acgctgacta cgctaaaatt gcggaagctc
    11461 aaggagctgt tggattcaca gttgaccgta tcgaagacat cgatgcagtt gttgcagaag
    11521 ctgttaaatt gaacaaagaa ggtaaaactg ttgtcatcga tgctcgcatc actcaacacc
    11581 gtccacttcc agtagaagta cttgaattgg atccaaaact tcactcagaa gaagctatca
    11641 aagccttcaa ggaaaaatac gaagcagaag aactcgtacc attccgtctc ttcttggaag
    11701 aagaaggatt gcaatcacgc gcaattaaat aattcctctc gccgaaaatc aaatatgaaa
    11761 cttgtagact ttattctttg attttcatag agcagaact
//
LOCUS       DAVKMJ010000052        11291 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000052 DAVKMJ010000000
VERSION     DAVKMJ010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11291
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.052"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            713..1705
                     /locus_tag="VW348_001796"
     CDS             713..1705
                     /locus_tag="VW348_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEU9746660.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1707..2525
                     /locus_tag="VW348_001797"
     CDS             1707..2525
                     /locus_tag="VW348_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEU9746661.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2527..3312
                     /locus_tag="VW348_001798"
     CDS             2527..3312
                     /locus_tag="VW348_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9746662.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLTQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3351..3629
                     /locus_tag="VW348_001799"
     CDS             3351..3629
                     /locus_tag="VW348_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEU9746663.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3614..3811
                     /locus_tag="VW348_001800"
     CDS             3614..3811
                     /locus_tag="VW348_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEU9746664.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
     gene            complement(4237..4329)
                     /locus_tag="VW348_001801"
                     /pseudo
     CDS             complement(4237..4329)
                     /locus_tag="VW348_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            4543..10962
                     /locus_tag="VW348_001802"
     CDS             4543..10962
                     /locus_tag="VW348_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU9746665.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     AENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEAKIKEENSNK
                     SQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGSKAIKELSSLKNTKVLYTYDRIF
                     NGGAIETTQDNLNKIKQIEGITSVERAQKVQPMMNHARKEIGVEEAIDYLKSINAPFG
                     KNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAF
                     NYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQIFSY
                     KMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRALRKAG
                     IPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQTVEFD
                     KVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKI
                     AVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGTKSQV
                     FSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKE
                     IDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVINGKST
                     YGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQNTAR
                     PMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGSISLK
                     EIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGKQIVP
                     EIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESVEEME
                     ALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGKPKIP
                     GTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSGSKIA
                     NIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVISREHF
                     IRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATKIRGQ
                     FEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLITKDTY
                     HKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYAGEGQ
                     GRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKGMISY
                     YLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKEKSSF
                     TIDRNISTIRDFENKDLKKLIKKKYKEEDDFVTGGKRTVELDYKYDDKGNITAYEDES
                     ALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEIKATK
                     YDSHSKTMTFDLYANINDIVDGLAFAGDMRFFVKDDDRIKAETKIRMPEKNKETKAEY
                     PYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGYALKV
                     TTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQAVLM
                     SALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKSNVEA
                     IKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWELRVN
                     ESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDGNVYL
                     QTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRNNGFD
                     GEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTGEVSE
                     LKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKDAGYV
                     INLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQREDH
                     SQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVGIFLG
                     LKKKNQD"
BASE COUNT         3959 a         1683 c         2259 g         3390 t
ORIGIN      
        1 attatggtat cgaatcttca tcagaatgat aaaattaatc aattgatatc tgattacaaa
       61 cagaatatga aagcttttta tatcactatt gaaaaattta tacgagatga tgaaagcctt
      121 aagtgttatt ttataaaggt tatttcaagt cgttccaagg taacaagtct agatcagatt
      181 gaagctgata aaacgataca aagaaaatat tcaagtgagc taaaaaaatt tattggattt
      241 tataatgaga ttatttgtga ggaaaatagt ttcctacatg tacgaaagag gtggtcgagt
      301 tggtttaggt agtcgatgcg tgagttgata attctcaggg tatggacttc tttttcatga
      361 atgaggtaaa agagcaggta ttgtttagag acaatcattc tgagcatatt ttctggatag
      421 agggagtatc cgattttatg atcaaagtta ataccgccct ctggtgagaa gatgagtagg
      481 ttggtaattt aaactattaa acagaatttt tgattaaaag tattatttta tgagagaaat
      541 cctaatttca caatccatag gcaaacgctt gcatttcgtt ttttattgga ctataatagg
      601 ttggtataaa gccttttgta gtaataaaat gtagaaggtg tagaaagcaa ggatttagaa
      661 tatttgtagt taaaaacaca atgttgctat tccttacgat agggagatag atatggcaat
      721 gatagaagtg gaacatcttc agaaaaattt tgtgaagact gttaaggaac cgggcttgaa
      781 gggggctttg cgctccttta ttcatcctga aaagcagacc tttgaagcgg tcaaggattt
      841 gacctttgag gttccaaaag ggcagatttt aggatttatc ggggcaaatg gtgctgggaa
      901 gtcgacaacc attaaaatgc tgacaggaat tttgaaacca acatctggtt tttgtcggat
      961 taacggcaag attccccagg acaatcggca agattatgtc aaagatattg gcgtagtctt
     1021 tggacaacgc acccagctat ggtgggattt ggctctgcaa gagacctaca ctgtcttaaa
     1081 agagatttat gatgtgccaa actcgctctt tcataagcgc atggactttt tgaatgaagt
     1141 cttggatttg aaggacttta tcaaggatcc cgtgcggact ctttcactgg gacaacggat
     1201 gcgggcggat attgcggcct ccttgctcca caatcccaag gttctttttt tagatgagcc
     1261 gaccattggt ttggacgttt cggttaagga taatattcgt cgggcaatta ctcagatcaa
     1321 tcaagaggaa gaaactacca ttcttttgac cactcacgat ttgagtgata ttgagcaact
     1381 ttgtgatcgg attttcatga ttgacaaggg gcaagagatt tttgatggaa cggtgagcca
     1441 actcaaggag acctttggta agatgaagac tctctctttt gaactgctac caggtcaaag
     1501 tcatctcgtc tctcactatg aaggtctgtc tgatatgacc attgatagac aaggaaacag
     1561 cctcaacatt gaatttgata gttctcgcta ccagtcagct gacattatca agcaaaccct
     1621 gtctgatttt gaaatccgcg atttgaagat ggtggatacg gatattgagg atattatccg
     1681 tcgcttctac cgaaaggagc tctaggatga tcaaattatg gagacgttat aaacccttta
     1741 tcaatgcagg ggttcaggag ttgattactt accgagtcaa ctttattctc tatcggattg
     1801 gcgatgtcat gggggctttt gtggcctttt atctctggaa ggctgtcttt gattcttcgc
     1861 aagagtcttt gattcagggc ttcagtatgg cggatatcac cctctacatc atcatgagtt
     1921 ttgtgaccaa tcttctgact agatccgatt cgtcctttat gattggggag gaggtcaagg
     1981 atggctccat tatcatgcgt ttgttgcgac cagtgcattt tgcggcctcc tatcttttca
     2041 ccgagcttgg ttccaagtgg ttgattttta tcagcgttgg ccttccattt ttaagtgtca
     2101 ttgtcttgat gaaaatcata tcgggtcaag gtattgtaga ggtgctagga ttaactgtca
     2161 tttatctttt tagcttaacg ctcgcctatc tgattaactt tttctttaat atttgctttg
     2221 gattttcagc ctttgtgttt aaaaatcttt ggggttccaa cctacttaag acttccatag
     2281 tggcttttat gtcggggagt ttgattccct tggcattttt tccaaaggtt gtttcagata
     2341 ttctctcctt tttgcctttt tcatccttga tttatactcc agttatgatc attgttggaa
     2401 aatacgatgc cagtcagatt cttcaggcac tccttttgca gttcttctgg ctcttagtga
     2461 tggtgggatt gtctcagtta atttggaaac gggtccagtc ctttatcacc attcaaggag
     2521 gttagtatga aaaaatatca acgaatgcat ctgattttta tcagacaata catcaaacaa
     2581 atcatggaat ataaggtaga ttttgtggtt ggtgtcttgg gagtctttct gactcaaggc
     2641 ttgaatctct tgtttctcaa tgtcatcttt caacatattc cattcctaga aggctggacc
     2701 tttcaagaga tagctttcat ttatggattt tccttgattc ccaagggaat ggaccatctc
     2761 ttttttgaca atctctgggc actagggcaa cgcctagtcc gaaaagggga gtttgacaag
     2821 tatctgactc gtcccatcaa tcctctcttt cacatcctag ttgaaacctt tcagattgat
     2881 gccttgggtg aactcttagt cggtggtatt ttattgggaa caacagtgac cagcattgtt
     2941 tggactcttc caaaattcct gcttttccta gtttgtattc cttttgcgac cttgatttat
     3001 acttctctta aaatcgcaac agccagtatc gccttttgga ctaagcagtc aggcgccatg
     3061 atttacatct tctatatgtt caatgacttt gctaagtatc cgatttctat ttacaattct
     3121 cttcttcgtt ggttgattag ctttatcgtg cctttcgcct ttacagccta ctatccagct
     3181 agctatttct tacaggaaaa ggatgtgttc tttaacgtag gaggtttgat gttgatttct
     3241 ctggttttct ttgttatttc ccttaaactt tgggataagg gcttagattc ctacgaaagt
     3301 gcgggttcgt aaaagctaaa gtaagactaa aatcaagaaa gaaacttatg atgtttgtaa
     3361 ttgaagaagt caaggatgaa aatcaaaaaa aggcagttgt cgctgaggtt ttgaaggatt
     3421 tgccagaatg gtttggaatc ccagaaagca cacaagccta tatagaagga accacgacac
     3481 tgcaagtttg gaccgcctat caggagagtg atttgactag atttgtaagc ttatcctatt
     3541 cgagtgaaga ttgtgcagag attgattgtc tcggcgtaaa aaagcttatc aaggtagaaa
     3601 aattgggagc caattgcttg ctactttaga gagtgaagct cgtaaaaaag ttggttatct
     3661 gcaggtcaaa acagtggcag aaggttctaa taaagattat gatcgaacaa atgactttta
     3721 tcgaggtctt ggctttaaaa agttagagat ttttcctcaa ctatggaatc cgcaaaatcc
     3781 ttgtcagatt ttgattaaaa agcttgaata atattacttg acatctattc tcagagtgct
     3841 atactgtaag tgtaatcgcc gatttagctt agttggtaga gcaaggcact cgtaaagcct
     3901 aggttatagg tagataaacg actgaggatt tgaaaaaata gataggtaga agataaccgt
     3961 taagccttac tcttagcggt tatttatatt gtttaatagc gctaatattt tatcaattat
     4021 gcctgttttc gtgtttctgg tagttgttca agtttattgc tactattttt gatggtatga
     4081 atgtgcttat aatgtatccc ggttaacgaa agttttggac ttatactctt cgaaaatctc
     4141 ttcaaaccac gtcaacgtcg ccttgccgtg cgtatggtta ctgacttcgt cagttctatc
     4201 cacaacctca aaacagtgtt ttgagctgac tacgtcagtt ccatctacaa cctcaaaaca
     4261 ctgttttgag caatctgcgg ctagtttcct agtttgctct ttgattttca ttgagtacta
     4321 atcttatttt ttaatgtgtg ctaaaaaata aattaactaa tgttaatttt tttgacttaa
     4381 atttttttaa atgatatact gtttttatag agagataaca attatatata aatgtactac
     4441 tctatttcct agataatact tagtaaaact ttttataaca aaggctagca aagttaaagt
     4501 ttattatcta ttggaagtta tataaatatg taaggaatta aaatgaaaaa aagtacagta
     4561 ttgtcattaa ccacagctgc agttatttta gcagcctatg cccctaatga ggtagtctta
     4621 gcagacacat ctagctctga agatgcttta agcatctctg ataaagaaaa agtagcagaa
     4681 aataaagaga aacataaaga tattcataat gctatagaaa cttcaaagga tactgaagaa
     4741 aagaaaacaa caattattga ggaaaaagaa gttgttagta aaaatcctgt gatagacact
     4801 aaaactagca atgaagaagc aaaaatcaaa gaagaaaatt ccaataaatc ccaaggagat
     4861 catacggact catttgtgaa taaaaacaca gaaaatccca aaaaagaaga taaagttgtc
     4921 tatattgctg aatttaaaga taaggaatct ggatcaaaag caatcaagga actatccagt
     4981 cttaagaata caaaagtttt atatacttat gatagaattt ttaacggtgg tgctattgaa
     5041 acaactcaag ataatctgaa taaaattaaa caaatagaag gtattacatc ggttgaaagg
     5101 gcacaaaaag tccaacccat gatgaatcat gccagaaagg aaattggagt tgaggaagct
     5161 attgattacc taaagtctat caatgctccg tttgggaaaa attttgatgg tagaggtatg
     5221 gtcatttcaa atatcgatac tggaacagat tataggcata aggctatgag aatcgatgat
     5281 gatgccaaag cctcaatgag atttaaaaaa gaagacttaa aaggaactga taaaaattat
     5341 tggttgagtg ataaaatccc tcatgcgttc aattattata atggtggcaa aatcactgta
     5401 gaaaaatatg atgatggaag ggattatttt gacccacatg ggatgcatat tgcagggatt
     5461 cttgctggaa atgatactga acaagatatc aaaaacttta acggcataga tggaattgca
     5521 cctaatgcac aaattttctc ttacaaaatg tattctgacg caggatctgg gtttgcgggt
     5581 gatgaaacaa tgtttcatgc tattgaagat tctatcaaac acaacgttga tgttgtttcg
     5641 gtatcatctg gttttacagg aacaggtctt gtaggtgaga aatattggca agctattagg
     5701 gcattaagaa aagcaggcat tccaatggtt gtcgctacgg gtaactatgc gacttctgct
     5761 tcaagttctt catgggattt agtagcaaat aatcatctga aaatgaccga cactggaaat
     5821 gtaacacgaa ctgcagcaca tgaagatgcg atagcggtcg cttctgctaa aaatcaaaca
     5881 gttgagtttg ataaagttaa cataggtgga gaaagtttta aatacagaaa tataggggcc
     5941 tttttcgata agaataaaat cacaacaaat gaagatggaa caaaagctcc tagtaaatta
     6001 aaatttgtat atataggcaa ggggcaagac caagatttga taggtttgga tcttaggggc
     6061 aaaattgcag taatggatag aatttataca aaggatttaa aaaatgcttt taaaaaagct
     6121 atggataagg gtgcacgcgc cattatggtt gtaaatactg taaattacta caatagagat
     6181 aattggacag agcttccagc tatgggatat gaagcggatg aaggtactaa aagtcaagtg
     6241 ttttcaattt caggagatga tggtgtaaag ctatggaaca tgattaatcc taataaaaaa
     6301 actgaagtca aaagaaataa taaagaagat tttaaagata aattggagca atactatcca
     6361 attgatatgg aaagttttaa ttccaacaaa ccgaatgtag gtgacgaaaa agagattgac
     6421 tttaagtttg cacctgacac agacaaagaa ctttataaag aagatatcat cgttccagca
     6481 ggatctacat cttgggggcc aagaatagat ttacttttaa aacccgatgt ttcagcacct
     6541 ggtaaaaata ttaaatccac gcttaatgtt attaatggca aatcaactta tggctatatg
     6601 tcaggaacta gtatggcgac tccaatcgtg gcagcttcta ctgttttgat tagacctaaa
     6661 ttaaaggaaa tgcttgaaag acctgtattg aaaaatctta agggagatga caaaatagat
     6721 cttacaagtc ttacaaaaat tgccctacaa aatactgcgc gacctatgat ggatgcaact
     6781 tcttggaaag aaaaaagtca atactttgca tcacctagac aacagggagc aggcctaatt
     6841 aatgtggcca atgctttgag aaatgaagtt gtagcaactt tcaaaaacac tgattctaaa
     6901 ggtttggtaa actcatatgg ttccatttct cttaaagaaa taaaaggtga taaaaaatac
     6961 tttacaatca agcttcacaa tacatcaaac agacctttga cttttaaagt ttcagcatca
     7021 gcgataacta cagattctct aactgacaga ttaaaacttg atgaaacata taaagatgaa
     7081 aaatctccag atggtaagca aattgttcca gaaattcacc cagaaaaagt caaaggagca
     7141 aatatcacat ttgagcatga tactttcact ataggcgcaa attctagctt tgatttgaat
     7201 gcggttataa atgttggaga ggccaaaaac aaaaataaat ttgtagaatc atttattcat
     7261 tttgagtcag tggaagaaat ggaagctcta aactccaacg ggaagaaaat aaacttccaa
     7321 ccttctttgt cgatgcctct aatgggattt gctgggaatt ggaaccacga accaatcctt
     7381 gataaatggg cttgggaaga agggtcaaga tcaaaaacac tgggaggtta tgatgatgat
     7441 ggtaaaccga aaattccagg aaccttaaat aagggaattg gtggagaaca tggtatagat
     7501 aaatttaatc cagcaggagt tatacaaaat agaaaagata aaaatacaac atccctggat
     7561 caaaatccag aattatttgc tttcaataac caagggatca acgctccatc atcaagtggt
     7621 tctaagattg ctaacattta tcctttagat tcaaatggaa atcctcaaga tgctcaactt
     7681 gaaagaggat taacaccttc tccacttgta ttaagaagtg cagaagaagg attgatttca
     7741 atagtaaata caaataaaga gggagaaaat caaagagact taaaagtcat ttcgagagaa
     7801 cactttatta gaggaatttt aaattctaaa agcaatgatg caaagggaat caaatcatct
     7861 aaactaaaag tttggggtga cttgaagtgg gatggactca tctataatcc tagaggtaga
     7921 gaagaaaatg caccagaaag taaggataat caagatcctg ctactaagat aagaggtcaa
     7981 tttgaaccga ttgcagaagg tcaatatttc tataaattta aatatagatt aactaaagat
     8041 tacccatggc aggtttccta tattcctgta aaaattgata acaccgcccc taagattgtt
     8101 tcggttgatt tttcaaatcc tgaaaaaatt aagttgatta caaaggatac ttatcataag
     8161 gtaaaagatc agtataagaa tgaaacgcta tttgcgagag atcaaaaaga acatcctgaa
     8221 aaatttgacg agattgcgaa cgaagtttgg tatgctggcg ccgctcttgt taatgaagat
     8281 ggagaggttg aaaaaaatct tgaagtaact tacgcaggtg agggtcaagg aagaaataga
     8341 aaacttgaca aagacggaaa taccatttat gaaattaaag gtgcgggaga tttaagggga
     8401 aaaatcattg aagtcattgc attagatggt tctagcaatt tcacaaagat tcatagaatt
     8461 aaatttgcta atcaggctga tgaaaagggg atgatttcct attatctagt agatcctgat
     8521 caagattcat ctaaatatca aaagcttggc gagattgcag aatctaaatt taaaaattta
     8581 ggaaatggaa aagagggtag tctaaaaaaa gatacaactg gggtagaaca tcatcatcaa
     8641 gaaaatgaag agtctattaa agaaaaatct agttttacta ttgatagaaa tatttcaaca
     8701 attagagact ttgaaaataa agacctaaag aaactcatta aaaagaaata taaggaagaa
     8761 gacgactttg taactggtgg aaaaagaaca gtagaacttg attataaata tgacgataaa
     8821 ggaaatataa ctgcctatga agatgaaagt gctctagaat atgaaactga aaaatttgac
     8881 gaaataaaat caaaaattta tggtgttcta agcccatcta aagatggaca ctttgaaatt
     8941 cttggaaaga taagcaatgt ttctaaaaat gccaaggtat attatggaaa taactataaa
     9001 tttatagaaa tcaaagcgac taagtatgac tcacattcaa aaacgatgac atttgattta
     9061 tacgctaata ttaatgatat tgtggatgga ttagcttttg ctggagatat gcggtttttt
     9121 gttaaagatg atgatcgaat aaaagctgaa actaaaatta gaatgcctga aaaaaataag
     9181 gaaactaaag cagaatatcc ctatgtatca agttatggga atgtaatcga attaggagaa
     9241 ggagatcttt caaagaacaa accagacaat ttaactaaaa tggaatctgg taaaatctat
     9301 tctgattcag aaaaacaaca atatctgtta aaggataaca tcattctaag aaaaggctat
     9361 gcactaaaag tgactaccta taatcctgga aaaacggata tgttagaagg gaatggagtc
     9421 tatagcaagg aagatatagc aaaaatacaa aaggccaatc ctaatctaag agtcctttca
     9481 gaaacaacaa tttatgctga tagtagaaat gttgaagatg gaagaagtac ccaagctgta
     9541 ttaatgtcgg ctttggacgg ctttaacatt ataaggtatc aagtgtttac atttaaaatg
     9601 aacgataaag gggaagctat cgataaagac ggaaatcttg tgacagattc ttctaaactt
     9661 gtattatttg gtaaggatga taaagaatac actggagagg ataagtccaa tgtagaagct
     9721 ataaaagaag atggctccat gttatttatt gataccaaac cagtaaacct ttcaatggat
     9781 aagaactact ttaatccatc taaatctaat aaaatttatg tacgaaatcc agaattttat
     9841 ttaagaggta agatttctga taagggtggt tttaactggg aattgagagt taatgaatcg
     9901 gttgtagata attatttaat ctacggagat ttacacattg ataacactag agattttaat
     9961 attaagttga atgttaaaga cggtgacatc atggactggg gaatgaaaga ctataaagca
    10021 aacggatttc cagataaggt aacagatatg gatggaaatg tttatcttca aactggctat
    10081 agcgatttga atgctaaagc agttggagtc cactatcagt ttttatatga taatgttaaa
    10141 cccgaagtaa acattgatcc taagggaaat actagtatcg aatatgctga tggaaaatct
    10201 gtagtcttta acatcaatga taaaagaaat aatggattcg atggtgagat tcaagaacaa
    10261 catatttatg taaatggaaa agaatataca tcatttgatg atattaaaca aataacagac
    10321 aagacactaa acattaagat tgttgtaaaa gattttgcaa gaaatacaac cgtaaaagaa
    10381 ttcattttaa ataaagatac gggagaggta agtgaattaa aacctcatag ggtaactgtg
    10441 accattcaaa atggaaaaga aatgagttca acgatagtgt cggaagaaga ttttatttta
    10501 cctgtttata agggtgaatt agaaaaagga taccaatttg atggttggga aatttctggt
    10561 ttcgaaggta aaaaagacgc tggctatgtt attaatctat caaaagatac ctttataaaa
    10621 cctgtattca agaaaataga ggagaaaaag gaggaagaaa ataaacctac ttttgatgta
    10681 tcgaaaaaga aagataaccc acaagtaaac catagtcaat taaatgaaag tcacagaaaa
    10741 gaggatttac aaagagaaga tcattcacaa aaatctgatt caactaagga tgttacagct
    10801 acagttcttg ataaaaacaa tatcagtagt aaatcaacta ctaacaatcc taataagttg
    10861 ccaaaaactg gaacagcaag cggagcccag acactattag ctgccggaat aatgtttata
    10921 gtaggaattt ttcttggatt gaagaaaaaa aatcaagatt aagataaaag ctatagaaaa
    10981 aaatggttta tgtactgaga ttagatagtg aggtgatgac atagttttgt gaaaacagcc
    11041 atttataact caattattta gtttacttca ctattgatac tatttggagt tattaatgga
    11101 cttagtttag ataactaatg aattgattga aagggttagt attgacaata ttggtcatat
    11161 tgattagaaa atagagtcta tcaaaattta aaggctaata gaggtgatga gacaatttcg
    11221 gctctttgtc aactgtagtg ggttgaagtc agctaagctc gagaaaggac aaattttgtc
    11281 ctttcttttt t
//
LOCUS       DAVKMJ010000053        11278 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000053 DAVKMJ010000000
VERSION     DAVKMJ010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11278
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.053"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            111..281
                     /locus_tag="VW348_001803"
     CDS             111..281
                     /locus_tag="VW348_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746666.1"
                     /translation="MKEAVKEFLKFRSRFTKIEWFEINQAVEARLNQKADQLKLDDVD
                     LEIISSRLEKVI"
     gene            complement(274..513)
                     /locus_tag="VW348_001804"
     CDS             complement(274..513)
                     /locus_tag="VW348_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746667.1"
                     /translation="MTEIHACLCGNWVNLSADDDCVMGPNMASPYIWWEENAELYSPI
                     SKPEANSMYHQDYIYIHYRGADYRIHPMFIQIVSR"
     gene            631..903
                     /locus_tag="VW348_001805"
     CDS             631..903
                     /locus_tag="VW348_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746668.1"
                     /translation="MEAVEIVRIKDVIIEKVSANDEELKRIFGCSKRQAGERRREMQK
                     LPSQQKHLLDSGQLVTIKGFYEYLQYRGTKAWKKEMETSKKMRSAG"
     gene            900..1115
                     /locus_tag="VW348_001806"
     CDS             900..1115
                     /locus_tag="VW348_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746669.1"
                     /translation="MNLLSRIKNYFSEEVKETNLDWKEVALDLNQSLIETQEKLQEAN
                     QEIADLKKIVAIYKEKEKEKRWNIFTW"
     gene            1094..1282
                     /locus_tag="VW348_001807"
     CDS             1094..1282
                     /locus_tag="VW348_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746670.1"
                     /translation="MEYIYLVTIVGIGLWSLVNKLDDHAEMKQKERQLMANNVARMNL
                     RNSDKQFTYDVEPPEGLK"
     gene            1294..1635
                     /locus_tag="VW348_001808"
     CDS             1294..1635
                     /locus_tag="VW348_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746671.1"
                     /translation="MTQAERIREYYREHPAASYDEVAEVVGTTNSNVRANLAKDIKAG
                     RCVRLEDKSYDYSPYYNHTQALTELVDWKNDNRREWVDMLTRAAEKETDSNVMRLLIK
                     EANKLMKEVTK"
     gene            1636..1866
                     /locus_tag="VW348_001809"
     CDS             1636..1866
                     /locus_tag="VW348_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746672.1"
                     /translation="MVRNKIGDLTNTLFAQLETLDDRDLTADELKVELHRSKQMVAIS
                     GQILQAGQLALDAEKFKDKVGEVNAPIALLEG"
     gene            1880..2602
                     /locus_tag="VW348_001810"
     CDS             1880..2602
                     /locus_tag="VW348_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEU9746673.1"
                     /translation="MHEICPGRLTPEVTRLLNEKFGTNYNKSQIGGVRKRLGLAVGKV
                     YQGRLLTKEQHDYLVLIQKNKISRNVANEMNQKFGLSLTEKQIKSYRRNNNLHSGLTG
                     RFEKGQTPHNKGKKYPNMPKNGGQFKKGNRPPNYVPVGTINYTTNGYPKEKIGEPNQW
                     VLKHRKVWEDHHGLIPKGYSIVFLDGDKTNYDISNLACLSKNEIARMNQNHLFTSNAD
                     LTKSGIGLTKLTNKIREVEKNG"
     gene            2595..3077
                     /locus_tag="VW348_001811"
     CDS             2595..3077
                     /locus_tag="VW348_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HEU9746674.1"
                     /translation="MASLYELTGQFLTIYQLDIDDETKADTLEAIDWQEQFEQKAEGY
                     AHVIKNLEADVAMYKAEEESFKAKKQVAQKKLDYVKDNIMAAMNVTGQTEVKSGALII
                     KIAKNPESVKVNEDDLPKKYFTKKVTLAPDKKTLKELLKSGKKVKGAELVRTEKLVIK
                     "
     gene            3077..3436
                     /locus_tag="VW348_001812"
     CDS             3077..3436
                     /locus_tag="VW348_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746675.1"
                     /translation="MELMNKTRVTDSLAVVIGPESIEVLVTEGFLFDVAIRFVKVDET
                     NLDQGNEKPVFTPEYKLVTVAKYKEKPIFESEEDIRKFEKQAKEVKSLFAFAKVNKQN
                     WFNTALYPGVLTEKVGV"
     gene            3436..3921
                     /locus_tag="VW348_001813"
     CDS             3436..3921
                     /locus_tag="VW348_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000696057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746676.1"
                     /translation="MKILAIDPSSNKIETSTTGVVLLDNARLVDSWVVSYGMRGFADW
                     FHEIGTNLEFDVVIVEEFKARDNDKSKDNSVAETIAYIQLCYPGAILQFNAGYKSDIP
                     NDLLKILDLWKFEKSHHQDIRAAARLGLFWAMRNDIEEVVHDIGKVVSEYHNNAKKVA
                     S"
     gene            3884..5077
                     /locus_tag="VW348_001814"
     CDS             3884..5077
                     /locus_tag="VW348_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III restriction endonuclease subunit R"
                     /protein_id="HEU9746677.1"
                     /translation="MSITITLRKWQAEAIKRSEHLSNGIFLEALGGRGKTICALAIAK
                     HKKAKKIIITNNRLAILNGWIDAVKFMNFDKGVEIIIQTDRYLQNQVKKGHKLDCDVL
                     IVDEWQNMSSDKQVALYRKIKRKYTIGLSATPIRKKGQNFYPLEKTVFGWATPNNKFD
                     WQKTHGKMVYDPFSYSKEKWEDFQNYESYISSLPNFFRWEEIEGIENAVENNGFEIKF
                     YQKRVASGNPEKLAEFRKLNLVTVDGKTAMAKQSFGRKTFERYLNQTGVAVDFPKLKP
                     VNADTPLMLQLDGLIERAPHDMLIVSKSKQIVNVISERHPEIGIWTGDIQEGLYKKFV
                     VATSQVLGVGVDGLQHKYQTIVVLDPVEEGSGEYDDYRQLLWRITGSRQQHDVNVIEF
                     YYKES"
     gene            5095..5412
                     /locus_tag="VW348_001815"
     CDS             5095..5412
                     /locus_tag="VW348_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746678.1"
                     /translation="MNKTTEMIVFRSRKTGEFLNSYKDRSSLAFAADFCSLEYCLKLP
                     RKKYEDNKKTYKALAAAFDCEIVAVEAEYKLTYPNGSEVEPIKRDRSSIEDMIKDIIG
                     GVL"
     gene            5412..6239
                     /locus_tag="VW348_001816"
     CDS             5412..6239
                     /locus_tag="VW348_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEU9746679.1"
                     /translation="MAFTLPANKPQVPKDTPRNFFIYGETMSGKSYLANEFPNPIVLN
                     TDGNAEANTVPSIQLINEKDDKGRITNSVIKQLGDILLALQTQKHSYETVVIDVIDDV
                     IEMIKIAVCDELTPVGKPRLKSLSEIPYGKGYDFFNQAITELVIDLKALPMNVIYISR
                     QVSEYDDNGNATKDKPSLKDKYVNLINGNSDLMIHTEKLGNNYNREVDRKRKTYYADQ
                     VDDKAILKILATIRGAVEPAKGKLAPKKEAAKTTKPAKTEKTKEAPKKEVDSDDELF"
     gene            6259..6765
                     /locus_tag="VW348_001817"
     CDS             6259..6765
                     /locus_tag="VW348_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746680.1"
                     /translation="MSLLDIAKSIKKEGFDPRKDSANGPAPIPAGTYPVVLKKATFNV
                     SDKGWESLGYQFEIRGGDYSGRSEFATFGTLTEWNGKNLDWAVERTMKFFIKALVLAG
                     DSMQGNEEDGKALEEALQRKAVGSYYNLVISVTKGKDGREFRNYDLEEEEAQPLTEAD
                     IDEDDLPF"
     gene            6938..7759
                     /locus_tag="VW348_001818"
     CDS             6938..7759
                     /locus_tag="VW348_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HEU9746681.1"
                     /translation="MPSMKEYALQYQKLGFSVIPINPKNKMPLIEFADKPAMTPSEIE
                     NFWDGYPNANIALKTTNFFVIDIDKHGKSNGFESLKKWKHLNLIEPTLQAKTASGGKH
                     LFYFKREDEPITQMIGFLPGVDIKAHENNYVLVAPSATDKGQYEWDLEKSKEGGTMVT
                     PSKYLIQSIKKQYGETHGYKYDGKDGLRDLVRRSHTRDRTQTTDLFETIALGFGDEGG
                     RNDKLAKFVGGLLYRAVDDGVVVQLARLANANSPTPLPEKEMMRTIESMIKKDRR"
     gene            7762..9105
                     /locus_tag="VW348_001819"
     CDS             7762..9105
                     /locus_tag="VW348_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEU9746682.1"
                     /translation="MIGNVVSIDSQPKMITTAKGDIKANSPSNVLMSFKADDQLSIYL
                     KHNDFSQEHELLKDIKIGNTLFKKGELPSNFDSVVKVYFESVLGVAFSSQAMLDGMET
                     FFSERSYNPVIEYMEKAAEKWDGRKRIDRMLQVYLGAEDIPLVSKIAQMWLVGAVAKV
                     YDPYVKFDYVLDLVGGQGVGKTSLLQKLGGEWYTDAVTDFSNKDNYDIMLKSLIVNDD
                     EMVASNRMSFAETKAFISKTSLRYRKPYMKRTEEFAKNFILARTTNQTEYLKDKTGER
                     RFLPVMADSKRQKKHPMEIEPETIEQIWGEAVTIYRAGADLMFDENTEDELNIYREQF
                     MYRDEVELQVLEYLDMPVPENWQNWSIQQQHQYTSKYFDNSSDFDPGSKKLDKVSTRE
                     MMYNLFMRNSNDRKLSTKINMIMDNHPDWKKSVFRAGGKSTKGFVRVKDSEKTNR"
     gene            9398..9553
                     /locus_tag="VW348_001820"
     CDS             9398..9553
                     /locus_tag="VW348_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746683.1"
                     /translation="MSYTVTLFFDNMVDETHFFKKESDAAKCKAQLESKYRGNRMYKV
                     KQEKLEE"
     gene            9550..10245
                     /locus_tag="VW348_001821"
     CDS             9550..10245
                     /locus_tag="VW348_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEU9746684.1"
                     /translation="MNKQELIKRIEDLPYTEGPIADTIEINRNWILKSIEQLAESEIG
                     HADEAPRYVKNILARLRELPLHDREFWLKAIMSEFEQDFSHAKWREGYEQGKIEGMVE
                     REKVIVPQCVAEYIEFKKKNNFHVYGAMRVIEDHYDKKVPDWFYENNIEKFCLAWLDG
                     YEVEKEKRYFVKIKGNIKENMLVYGELLKRYFFTKSFSLDDVIYSHTRKELENAKIGW
                     VFDCEGFEIEEVE"
     gene            10403..10663
                     /locus_tag="VW348_001822"
     CDS             10403..10663
                     /locus_tag="VW348_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1372 family protein"
                     /protein_id="HEU9746685.1"
                     /translation="MKRFIAIWILLSAGLNIWQSIYIKKLEEKRPIVVYKADNAGAEI
                     FGKVVEKGRHGKLYTLTIRDYGVFVVTKDVYEKVKVGDEVLL"
     gene            10663..11121
                     /locus_tag="VW348_001823"
     CDS             10663..11121
                     /locus_tag="VW348_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000340952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746686.1"
                     /translation="MDDILQALAKMLNMTVDEVSSLLTTFKGNAPQIYEMFVKEKMFY
                     DLFSLFQIMSIVIFSISAVVLAVLTLIYFTYDGGFVYSYDIRTGKTEEEIKLERIERK
                     RKDLKIPLKISCISSSASLITLVIAIVLKATLAPNYIFIVNEILPKLTKR"
     gene            11169..11237
                     /locus_tag="VW348_001824"
                     /pseudo
     CDS             11169..11237
                     /locus_tag="VW348_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022916.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
BASE COUNT         4002 a         1874 c         2472 g         2930 t
ORIGIN      
        1 tacttcatca gcgaatctac aacgtacaga gaagcaaaaa tagcgtgtga gaagctattg
       61 aaacaagtca gccacgagat tgaactcagg gcgatggaaa gtaggacagt atgaaagaag
      121 cagtaaagga atttctaaaa ttcaggagcc gatttacaaa aatagaatgg tttgaaatca
      181 accaagctgt cgaagctcgt ttaaatcaaa aagccgacca gttgaaactg gacgacgtag
      241 atttagaaat catttctagc agactagaaa aagttatcta gaaacgattt gaatgaacat
      301 tggatggata cgatagtcag cgccacgata gtgaatgtag atataatcct gatggtacat
      361 cgagtttgct tcaggtttag aaattggtga gtagagttct gcattttctt cccaccaaat
      421 gtaaggacta gccatatttg gtcccattac acaatcgtcg tcggctgata ggttcaccca
      481 atttccgcaa agacatgcgt gaatttcagt cataatatta cctcctttct ggtttcatta
      541 tagcagaaaa ggagatagca aaaaagcacc tgacggaaat caggcgcata cttaaatatt
      601 caacatgatt ataacacgaa aggagcaaaa atggaagcag ttgaaattgt aagaattaaa
      661 gatgtgatta ttgaaaaagt ctctgctaat gatgaagagt taaaacgtat ctttggatgt
      721 tcaaaacgac aagcaggaga gcgaagaaga gaaatgcaaa aactccctag tcagcaaaaa
      781 catcttttgg atagtggaca acttgtaacg attaaaggtt tctatgaata cttgcaatat
      841 cgtggaacta aagcttggaa aaaagaaatg gaaacaagca agaaaatgag gtcagcagga
      901 tgaacctact atcaagaatc aaaaactatt tttcggaaga ggtcaaagaa actaatctcg
      961 actggaaaga ggtcgcttta gacctcaatc aatcactaat tgaaacacag gaaaaacttc
     1021 aagaagcgaa tcaagaaatc gcagacttga agaaaatcgt agcaatctat aaagaaaagg
     1081 agaaagaaaa acgatggaat atatttacct ggtaacaatc gtaggaattg gactatggtc
     1141 gctagtaaat aaactagatg accacgctga aatgaaacaa aaagagcgcc agctgatggc
     1201 aaacaatgtc gcacggatga atctgagaaa ttcagataag caatttactt atgatgtaga
     1261 accgcctgaa gggttgaaat aaggaggaga aacatgactc aagctgaacg aattagggaa
     1321 tattatagag agcaccctgc tgcctcatat gatgaagtgg ctgaggtcgt tggtacaaca
     1381 aatagtaatg tgagagcgaa cctggccaaa gacatcaagg caggcagatg cgttcgcttg
     1441 gaagataagt catacgatta ctcgccttac tataaccata cacaggcact cactgagttg
     1501 gttgactgga agaatgacaa cagacgtgag tgggtggata tgctgacaag agcagcagag
     1561 aaagaaacgg atagcaacgt tatgcgtttg ttaatcaaag aagcaaataa attgatgaaa
     1621 gaggtgacta agtagatggt acgaaataaa ataggtgatt taactaacac gctcttcgct
     1681 caattagaga ctctggatga tagggatctt acagcagatg aattaaaagt agaattacac
     1741 cgctcgaaac aaatggtcgc aatctcaggt caaatcttac aagcaggtca attggcgcta
     1801 gatgctgaaa aattcaaaga caaggtaggt gaagtcaatg ccccgatcgc tttgctggaa
     1861 ggatgagtac acggagtaca tgcatgaaat atgccctggt cgtttaactc ctgaagtaac
     1921 caggttgctg aatgaaaaat ttggtacgaa ttataacaag agtcaaatcg gtggcgtacg
     1981 caaacgtcta gggttagcag ttggaaaagt ctatcaaggt cgattgctga caaaggagca
     2041 acatgattat cttgtattga tccaaaaaaa taagatttct cgtaatgtcg caaatgaaat
     2101 gaaccaaaaa tttggcttat cgctaactga gaaacagatt aagagttatc ggagaaataa
     2161 taatctacat agtggtttga caggaagatt cgagaaaggt cagactcctc acaataaggg
     2221 gaagaagtac cccaatatgc caaaaaacgg cgggcagttc aaaaaaggta atcgacctcc
     2281 gaattatgta cctgtcggta ctatcaacta cacaacaaac ggttatccaa aagaaaagat
     2341 tggagaacct aatcaatggg ttttgaaaca ccgcaaggtt tgggaggacc atcacgggct
     2401 gataccaaaa gggtactcaa tcgtttttct ggacggtgat aaaacaaact atgatatttc
     2461 aaatctggca tgtttatcta agaacgaaat tgctagaatg aatcaaaatc atttattcac
     2521 gtccaacgct gatttgacta aatcaggtat tggactaaca aaacttacaa ataaaatcag
     2581 agaggtagaa aaaaatggct agtttatacg aactaacagg tcagttcctg acaatttacc
     2641 aattggatat cgatgacgaa acaaaagcag acacgcttga ggccatcgat tggcaagaac
     2701 aatttgaaca gaaagcagaa ggatatgccc atgttatcaa gaatctagaa gccgacgtgg
     2761 caatgtacaa ggctgaggaa gagagcttca aagccaagaa acaggtggca cagaaaaagc
     2821 tggattatgt caaggataac attatggcag ctatgaatgt cacggggcaa accgaagtta
     2881 agagtggtgc cctgattata aaaattgcta agaatccaga atcagtcaag gtcaacgaag
     2941 acgaccttcc gaaaaaatat tttacaaaaa aagtgacgct tgcgccggac aaaaaaacac
     3001 tcaaagagtt gcttaaatct ggcaagaaag tcaaaggtgc ggagcttgtc cggacagaaa
     3061 agttggtgat taagtaatgg aattgatgaa taaaacacga gtaacagatt cactagcagt
     3121 tgtgattgga ccagaatcga ttgaagtact tgttactgaa ggttttctat ttgatgttgc
     3181 gattcgtttt gtaaaagtag acgaaacaaa tcttgatcaa ggaaatgaaa agccagtatt
     3241 cactccggaa tacaagctgg tcacagttgc taaatacaag gaaaaaccta tctttgaatc
     3301 ggaggaagat attcgaaaat ttgagaagca agcaaaagaa gttaaatcgc tatttgcctt
     3361 tgcaaaggta aataaacaaa attggtttaa cactgccctt tatccaggag tgctgactga
     3421 gaaagttggt gtttgatgaa aattttagct attgatccaa gtagtaataa aattgaaacc
     3481 agcacaacag gagttgtctt gttggataat gcaagattag ttgatagctg ggttgtctct
     3541 tatggtatga gaggtttcgc tgattggttt cacgaaatcg gaacaaatct tgaattcgat
     3601 gtagttattg ttgaagaatt taaggcgagg gataacgaca agtcgaaaga taatagcgtg
     3661 gcagaaacca tcgcctatat ccaactttgc tatccaggtg ccattcttca attcaatgca
     3721 ggttacaagt cggatattcc aaacgatctt ttgaaaatct tagacctttg gaaatttgaa
     3781 aaaagtcatc atcaagatat tcgagcagca gcaagacttg gattattttg ggcaatgaga
     3841 aatgatattg aagaagtggt tcatgatatc ggaaaggtgg tgagtgagta tcacaataac
     3901 gctaagaaag tggcaagctg aagcgattaa aagaagtgaa catttatcta atggaatctt
     3961 tttagaggct cttgggggca gaggcaaaac tatctgtgca cttgctattg caaaacataa
     4021 aaaagctaaa aaaatcatca tcacaaacaa tcgactagct attctgaatg gttggataga
     4081 tgcagtcaag tttatgaatt ttgataaagg tgttgagatt atcattcaga cagatagata
     4141 tcttcaaaat caagtcaaaa aggggcataa attagattgt gatgtgctga tagtagacga
     4201 atggcagaat atgtcttctg acaaacaagt ggccttatat cgcaaaataa agcgaaaata
     4261 cacgataggt ctttcagcga caccaattcg gaaaaaagga caaaatttct atccgcttga
     4321 aaaaacggta tttggttggg caaccccaaa taataaattt gactggcaaa agactcatgg
     4381 aaaaatggtc tatgatccat ttagctattc aaaagagaag tgggaagatt ttcaaaatta
     4441 tgaaagttat atctcgagct tgcctaattt cttccgctgg gaagagattg aaggaattga
     4501 gaatgcagtt gagaataacg gttttgagat taagttttac caaaagagag tcgcctctgg
     4561 caatccagaa aaacttgcag aatttagaaa actaaatctt gtaacagtgg acggcaaaac
     4621 tgcaatggcc aagcaatcgt ttggaagaaa gacctttgaa cgctacctta atcaaacagg
     4681 cgtagcagtc gattttccaa aattaaagcc agtaaatgcg gatacgccat tgatgttaca
     4741 acttgacggt ttaatcgaac gagcaccaca cgatatgttg attgtcagta aatctaagca
     4801 gattgtcaac gtcattagcg agcgccatcc tgaaattgga atctggacgg gcgatattca
     4861 agaaggactt tataagaaat tcgtggttgc tactagtcaa gtgttaggtg tcggagtaga
     4921 cggcttgcaa cacaaatacc aaactattgt cgtattggat ccagtagaag aaggttctgg
     4981 agaatatgat gattatcgac aattgctctg gcgcataaca ggaagtcgtc agcagcatga
     5041 tgtaaatgta attgaatttt attataaaga aagttaaaaa aagaggaaaa caaaatgaat
     5101 aaaacaactg aaatgatcgt atttcgtagc cgtaaaactg gagaatttct taattcttac
     5161 aaggacagaa gttctttagc atttgcagct gacttttgca gcttggaata ttgtttgaag
     5221 cttcctcgta aaaaatacga agacaacaaa aagacttaca aggctcttgc tgcagctttt
     5281 gactgtgaaa ttgtcgcagt tgaagcggaa tacaaattga cctatccgaa tggatcagaa
     5341 gttgaaccta tcaagcgtga ccgttcatca attgaggaca tgattaagga tattattgga
     5401 ggggttctct aatggcattt acacttccag caaataaacc acaagttcct aaagataccc
     5461 cacgaaattt tttcatctac ggcgaaacca tgagcggaaa gtcttatctt gcaaatgaat
     5521 tcccaaatcc aatcgttttg aacacagacg ggaatgcaga agctaacact gttccaagca
     5581 ttcagctgat caatgaaaaa gatgacaagg gacgaattac caattcagta attaagcagc
     5641 ttggagatat cttgcttgct ctccagacac agaagcactc ttatgaaaca gtcgttattg
     5701 atgtaattga cgatgttatt gaaatgatta agattgcagt ttgtgatgaa ttaaccccag
     5761 ttggtaaacc tcgcttgaaa tccttgtcgg aaattccata cggcaaagga tacgacttct
     5821 ttaaccaagc tatcacagaa ttagtcattg acctcaaagc attgccaatg aatgttattt
     5881 acatcagccg tcaggtatct gaatatgatg acaatggcaa tgccaccaaa gacaagccaa
     5941 gcttgaaaga taagtatgtc aatcttatca atggaaactc tgatttgatg atccacactg
     6001 aaaaactcgg caacaactac aaccgtgagg ttgaccgcaa gcgtaagacc tattatgcgg
     6061 accaggttga tgacaaggcc atcttgaaaa tcttggcaac tatccgtggg gctgttgagc
     6121 ctgcaaaggg caagctagcc cctaaaaaag aagcagctaa gacaactaaa ccagctaaga
     6181 ccgaaaaaac aaaagaggca cctaagaaag aagttgactc tgatgatgaa ctattttaag
     6241 aaataaagga gaatacacat gagcttacta gatatcgcaa aatcaatcaa aaaagagggc
     6301 tttgacccac gcaaagacag cgccaacggt cctgcaccaa tcccagctgg tacttatcca
     6361 gtagtcctga agaaagcaac cttcaacgta tcggacaaag gctgggaaag ccttggttat
     6421 caatttgaaa tccgtggcgg tgattacagt ggacgctctg aatttgcaac atttggcaca
     6481 ctgactgaat ggaacggtaa gaaccttgac tgggcagttg aacgcactat gaaattcttt
     6541 atcaaagcct tggtccttgc tggcgacagt atgcaaggaa atgaagaaga cggtaaagcc
     6601 ttggaagagg ctctacaacg taaggcagtt ggctcttact acaaccttgt tatctctgtg
     6661 actaagggga aagatggccg tgagttccga aactatgacc ttgaagaaga agaagcacaa
     6721 ccgctgactg aagctgatat cgatgaagat gacctccctt tctaaaaaat agcaagtttt
     6781 gggtcattga tgaaactgat gaaagattag gaccattcaa tacatttgaa gaggcttatc
     6841 aatcgttgtt attttattta aaaatgactg aagatgaata tcagtcaaac tatacggccc
     6901 aggaacttgt ttatatttac aaagaggaga aaaaaccatg ccgtcgatga aagaatacgc
     6961 attacagtac caaaagttag ggttctcagt cattccaatc aatcctaaaa acaagatgcc
     7021 tttaatcgaa tttgctgata aaccagccat gactccatct gagattgaaa acttttggga
     7081 cggctaccct aatgcaaaca ttgccctaaa gactaccaac ttctttgtca ttgatattga
     7141 caaacacggc aaatcgaacg gttttgaatc gctaaaaaaa tggaaacatc taaatttaat
     7201 cgaaccgaca ctgcaagcta agacggctag tggcggtaaa catctattct acttcaaacg
     7261 agaagatgag ccgatcactc agatgattgg attcttgcct ggtgttgata ttaaggctca
     7321 cgaaaataat tatgtgttag tcgcaccctc tgccacagat aaagggcagt atgagtggga
     7381 tctggaaaag tctaaggaag gtggcacgat ggtcactcct tcaaaatatt taatccagtc
     7441 tataaaaaaa cagtatggcg aaactcacgg ttataagtat gatggtaagg acggtcttag
     7501 ggatttagtt agacgttcac atactagaga ccgaacacag actacagatc tctttgaaac
     7561 catcgccctt ggttttggtg atgaaggtgg acgaaatgac aaactagcaa aattcgtagg
     7621 tggtctctta tatcgtgcgg tcgacgatgg tgtagttgtt caacttgcaa gattagcaaa
     7681 tgcaaatagt ccaacccctt tgcctgaaaa ggaaatgatg cgtactattg aaagtatgat
     7741 taaaaaagat aggaggtgat tgtgattggt aatgtagtaa gtattgactc acaacctaag
     7801 atgataacga ctgccaaggg agacatcaag gccaacagtc caagtaatgt gttgatgtct
     7861 ttcaaagctg atgatcagtt gagtatttac ctaaagcaca acgatttttc ccaagagcat
     7921 gaactcctta aagatatcaa gatcggcaac actcttttta aaaaaggtga gctcccttct
     7981 aactttgatt cagtcgtaaa agtttacttt gaaagtgtgt taggtgttgc tttctctagc
     8041 caggcgatgc tggacggcat ggaaactttt ttctcagaac gttcttacaa tccagtcatt
     8101 gagtatatgg aaaaggctgc tgaaaaatgg gatggtcgta aacgaattga ccgaatgctt
     8161 caggtttacc tgggggctga agatatccct ttagtttcta aaatcgctca aatgtggcta
     8221 gttggtgcag ttgctaaagt ttatgatcca tacgttaagt ttgactatgt tctggatcta
     8281 gtcggtggac aaggagttgg gaaaacatcc ctccttcaaa aattgggtgg cgaatggtat
     8341 acggatgccg taacagattt ctctaataaa gataattacg acattatgtt aaagagtcta
     8401 atcgtcaacg acgacgaaat ggtggccagt aatcggatga gctttgcaga aactaaggcc
     8461 tttatttcta aaactagcct acgttatcgt aaaccataca tgaaacgcac agaagagttt
     8521 gccaaaaact tcattttagc tagaactact aaccaaacag aatacctcaa ggacaaaacc
     8581 ggtgaacgtc gttttctacc agttatggca gatagtaaac ggcaaaaaaa acatccaatg
     8641 gaaatcgagc cagagacaat tgaacaaatc tggggcgaag ccgttacaat ctatcgtgct
     8701 ggtgctgatt tgatgtttga tgaaaataca gaggatgaac tgaatatcta ccgtgaacag
     8761 ttcatgtatc gtgatgaagt tgaattacaa gtgcttgaat atcttgatat gcccgtccct
     8821 gaaaattggc aaaactggtc tattcagcaa caacatcaat acacaagtaa atatttcgat
     8881 aatagtagcg actttgatcc tggaagcaaa aaactagata aggtctcaac tcgtgaaatg
     8941 atgtacaact tatttatgag aaattcgaat gacaggaagc tgtcaacgaa gattaacatg
     9001 atcatggata atcatcctga ttggaaaaaa agtgttttcc gggcaggagg taaaagtaca
     9061 aaagggttcg taagagtgaa agattcggaa aaaactaatc ggtagcaatt aaaaaattat
     9121 cggtagtcat cggtagcagt tgagggggag atcggtagca ttctaccgat aaaataggac
     9181 atcggtagca catcggtagc agtctaaccc cttgatatta ctgactttta tttaatattt
     9241 atatataatg ctactcttct acctatattt ttaaaaaaag tatataaaat aatagtaata
     9301 ataaagaaag cctatagaat agggattctt gaaaaaaact ttttactttt tagaatttat
     9361 cggtagcacg gtagcagttt agaaaaaaga ggtaaaaatg tcatacacag taacattatt
     9421 ttttgacaac atggtagacg aaactcactt ttttaagaaa gagagtgatg ctgccaaatg
     9481 caaggctcag ttagaaagca agtatcgagg gaatcgaatg tataaagtta agcaggagaa
     9541 attggaagaa tgaataagca ggaactgatt aaacgtatcg aggatttgcc ttatacagag
     9601 gggcctatcg cagatacaat cgaaattaat agaaattgga tattgaaatc aattgaacag
     9661 ctagccgaat ccgaaatagg tcacgcagat gaagctccac gctacgtaaa gaacatacta
     9721 gcacgattgc gagaattgcc attgcatgat agagagtttt ggttaaaggc tatcatgagc
     9781 gaatttgaac aggattttag ccatgcaaaa tggcgagagg gctacgagca aggtaaaatt
     9841 gagggtatgg ttgaacgtga aaaagtcata gttccgcagt gtgtggcgga atatatagaa
     9901 tttaaaaaga aaaacaattt tcatgtttac ggtgcaatga gagtaattga agatcattat
     9961 gataagaaag ttcctgattg gttttacgaa aataacatcg aaaaattctg tcttgcttgg
    10021 cttgacggct acgaggttga aaaagagaag cggtattttg ttaagattaa agggaatatt
    10081 aaagaaaata tgttggttta tggagaactt ttgaaaaggt atttctttac aaaaagcttt
    10141 agtttagacg atgttatata ttcccacacc cgtaaagaac tagaaaatgc aaaaatcggc
    10201 tgggtgtttg attgtgaagg gtttgagatt gaggaggtgg agtgatgagc cttacgctaa
    10261 atagcacaat tggagactta gttttggcaa tcggagaaat tatcgttggt tctgatggta
    10321 aaaccactac agcgatactg gagatacctg atcaaagctt ttacttagag attgagctta
    10381 aattgaagga ggaggtcata aattgaaacg attcatagct atctggattc tgctatctgc
    10441 tggattgaat atctggcaga gtatctacat taaaaagtta gaagaaaagc gccctattgt
    10501 cgtctataaa gctgataacg caggcgctga gatattcggt aaagtcgtcg agaaaggacg
    10561 gcatggcaag ctatacacgc ttaccattcg tgactacggg gtgttcgtgg ttacgaagga
    10621 cgtgtatgag aaagtgaaag taggggatga ggtgttactc taatggatga tattttacaa
    10681 gctttagcaa aaatgctaaa tatgactgtt gatgaagtaa gttctttgct tacaacattt
    10741 aaagggaatg caccacagat ttatgaaatg ttcgttaaag aaaagatgtt ttatgatctc
    10801 ttcagtcttt ttcaaatcat gtcaattgta atatttagta tttctgcagt agttttagca
    10861 gttttaactc tcatatattt tacatacgat ggtggttttg tttattccta tgatatacgt
    10921 acaggaaaaa ccgaggaaga aattaaatta gaacgcattg aacggaaaag aaaggactta
    10981 aaaataccac taaaaattag ttgcatttca tcaagcgcaa gtttgataac attagttatt
    11041 gcaattgttt taaaagcaac tcttgcacct aattatatat tcatcgtgaa tgagatttta
    11101 ccaaaattaa cgaagagata ggagttatca tgaacgcact agaaaaagtc gaacaatggt
    11161 ttatcgaccg tgaaatcaaa gaccgaaaag gtcgctggat tgatggctcg tttgtcaaag
    11221 aggaggattt ggcatgatac cgaaatttag agtgtgggta aaaataggaa aacgtatg
//
LOCUS       DAVKMJ010000054        11124 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000054 DAVKMJ010000000
VERSION     DAVKMJ010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11124
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.054"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            101..463
                     /locus_tag="VW348_001825"
     CDS             101..463
                     /locus_tag="VW348_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746687.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNALKIANLVLGIIAIVYYKGDKRVGAAPSVLMIVSGEVSLIPFLGWVGGILA
                     IIGGSLFLATLKKFKSEE"
     gene            759..947
                     /locus_tag="VW348_001826"
     CDS             759..947
                     /locus_tag="VW348_001826"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746688.1"
                     /translation="MENNDSFTKLKESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQ
                     TVLSFLVLTSFFVKNCVK"
     gene            998..1690
                     /locus_tag="VW348_001827"
     CDS             998..1690
                     /locus_tag="VW348_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEU9746689.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            1743..4153
                     /locus_tag="VW348_001828"
                     /pseudo
     CDS             1743..4153
                     /locus_tag="VW348_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
     gene            4403..5104
                     /locus_tag="VW348_001829"
     CDS             4403..5104
                     /locus_tag="VW348_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9746690.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDVLNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            5106..7814
                     /locus_tag="VW348_001830"
     CDS             5106..7814
                     /locus_tag="VW348_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEU9746691.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQCSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATDQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMSQSAVSSVVQNASAIRLFDSVASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTTKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(7910..8401)
                     /gene="tpx"
                     /locus_tag="VW348_001831"
     CDS             complement(7910..8401)
                     /gene="tpx"
                     /locus_tag="VW348_001831"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEU9746692.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(8524..9453)
                     /gene="psaA"
                     /locus_tag="VW348_001832"
     CDS             complement(8524..9453)
                     /gene="psaA"
                     /locus_tag="VW348_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEU9746693.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(9485..10333)
                     /locus_tag="VW348_001833"
     CDS             complement(9485..10333)
                     /locus_tag="VW348_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEU9746694.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(10330..11052)
                     /locus_tag="VW348_001834"
     CDS             complement(10330..11052)
                     /locus_tag="VW348_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEU9746695.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT         3264 a         2072 c         2534 g         3254 t
ORIGIN      
        1 tatacaaatt tttattttat aatatcagaa aatacttttt ttttaaaaag caaatatgat
       61 acaattttat ttgaaaaaaa ataaaaaagg agattttatt atgaaatcaa gtggtatcgt
      121 cggtcttgtg ggaggaattt tacttcttat ttgtcctttt gtcttgttgg gaacagcggt
      181 aaacacagct gctacaactc ttaatggagg agctactgca ggggcttttt caggtgttgc
      241 cttactcttg aatgccttga agattgcaaa tcttgttctt ggtatcattg ctattgttta
      301 ctataaagga gataagcgtg taggtgcagc tccgtctgta ctaatgattg tttctggtga
      361 agttagtctc attccattct taggatgggt tggggggatt cttgctatta tcggaggatc
      421 tctattcctt gcaacattga agaaattcaa atcagaagaa taaaaggtat tttagcatga
      481 aaagaacaaa aaagtttatc ggtataggag tagctctatt atctctttct cttctagttg
      541 catgtggaac ataaagttca aagaatactt caacaagtaa tgatgagaag acagtagcaa
      601 catccaatag ttcaaaagaa acaatcactt tcgatacacc ggttgtaaca gacgatgcga
      661 ttgaatcaat acgcacttat gcagattata tagatcttta taaaaatatt tttgatgatt
      721 attttactaa aactgaggaa ggtttcaaag gcacagctat ggaaaataat gactcgttta
      781 ctaaactaaa agagtcaact caaaaattat tcgatgcgca gaaaaaaagg ttaaataatg
      841 aagatagaat agaaacaacc aaaaacaatg tgattgccaa acattgtcaa acagtccttt
      901 cctttttggt tttgactagc ttttttgtga aaaattgtgt aaaatagaat agataaacga
      961 ggggaaacct cggaaaattt aaaggagaat ccatctaatg gtaaaattgg tttttgctcg
     1021 ccacggtgag tctgaatgga acaaagctaa ccttttcact ggttgggctg atgttgattt
     1081 gtctgaaaaa ggtacacaac aagcgattga cgctggtaaa ttgatcaaag aagctggtat
     1141 caaatttgac caagcttaca cttcagtatt gaaacgtgct atcaaaacaa ctaacttggc
     1201 tcttgaagct tctgaccaat tgtgggttcc agttgaaaaa tcatggcgct tgaacgaacg
     1261 tcactacggt ggtttgactg gtaaaaataa agctgaagct gctgaacaat ttggtgatga
     1321 gcaagttcac atctggcgtc gttcatacga tgtattgcct ccaaacatgg accgtgatga
     1381 tgagcactca gctcacacag accgtcgtta cgcttcactt gacgactcag ttatcccaga
     1441 tgctgaaaac ttgaaagtga ctttggaacg tgctcttcca ttctgggaag ataaaatcgc
     1501 tccagctctt aaagatggta aaaacgtatt cgtaggagct cacggtaact caatccgtgc
     1561 ccttgtaaaa cacatcaaag gtttgtcaga tgacgagatc atggacgtgg aaatccctaa
     1621 cttcccacca ttggtattcg aattcgacga aaaattgaac gtcgtttctg aatactacct
     1681 tggaaaataa aaaattgtaa gtctagaatt gatttctagg ctttttatgt tagtatggaa
     1741 gtatgataag gaataaaaaa caagattatg tactggccta caagcaacca gcttcaacca
     1801 cttacatggg ttgggaagaa gaagctttac cgataggcaa tggttcttta ggagcaaaag
     1861 tatttggcct tataggggct gaacggattc aatttaatga aaaaagtctc tggtctggag
     1921 gtccacttcc tgatagttca gattatcagg gtggaaatct tcaggatcag tatgtttttt
     1981 agctgagatt cggcaggctt tggagaagag agattacaat ctggctaagg aactggctga
     2041 gcagcaccta attgggccaa aaacgagtca atatgggacc tatctgtctt ttggggatat
     2101 tcacattgag ttcagccagc aaggtacgac tttgtctcag gtgacggact atcagagaca
     2161 gctgaatatt agtaaggcac ttgcgacgac ttcttatgtc tataagggaa cgcgatttga
     2221 acgtgaagct tttgcgagtt ttccagatga tctcttggtt caatgtttta ctaaggaagg
     2281 gttggaaact ctagatttta ctatagaact atccttgacc tgtgatttgg cttctaatgg
     2341 aaagtatgaa caggaaaagt ctgattacaa ggagtgtaag ttggatatta ctgattctca
     2401 tatcttgatg aagggaagag ttaaggataa tgatctgcgg tttgctagtt atctagcttg
     2461 ggaaacggat ggagatatta gagtttggtc atatagggtt cagatatcag gagccagtta
     2521 tgccaatctc ttcttggccg ctaagacgga ttttgcccaa aatcctgcta gcaattatcg
     2581 caagaaacta gatttagagc aacaggtgag agacttggtg gacacagcta aagaaaaggg
     2641 ctatacccaa ttgaaatcaa ggcatatcga ggactaccaa gccttattcc agcgtgttca
     2701 attggatttg gaagctgatg ttgacgcatc cactacagat gatttgttaa aaaattataa
     2761 gccacaagaa gggcaggctt tggaggagct gttcttccag tatggacggt atttattgat
     2821 tagttcgtcc agagactgcc cagatgctct accagctaac ctacagggag tctggaatgc
     2881 ggtcgacaat cctccttgga attcggacta tcacttaaat gtcaatctgc agatgaatta
     2941 ttggccagcc tatgttacca atctcctaga ggcggtcttt ccggtcatca actatgtaga
     3001 tgatttgcgt gtctatggtc gtctagcggc tgtaaagtat gcaggaatcg tctctcaaaa
     3061 aggtgaggaa aatggttggt tggttcatac tcaagcgact ccctttggtt ggacggcacc
     3121 tggttgggat tactattggg gttggtcacc agctgccaat gcgtggatga tgcaaaccgt
     3181 ttatgaagcc tattcatttt atagggacca agactatctc agagagaaaa tttatcccat
     3241 gttgagggaa acggttcgtt tttggaatgc ctttttacat aaggatcagc aggcgcagcg
     3301 ttgggtgtct tctccgtctt attccccaga acatgggccg atttcgattg gcaatactta
     3361 tgaccaatct ctaatttggc agttatttca tgattttatt caggctgctc aggaattggg
     3421 actggatgag gacttgttga ctgaggttaa ggagaagtct gatttactaa atcctttgca
     3481 aatcactcaa tctggtcgaa tcagggagtg gtatgaggag gaagagcagt attttcaaaa
     3541 tgagaaagtg gaggcccagc atcggcacgc ttcccatcta gtgggactct atcctggcaa
     3601 tctctttagc tacaagggac aagagtatat tgaagcggcg cgtgctagcc tcaatgatcg
     3661 tggagatggc ggcacaggct ggtccaaggc taataagatc aatctctggg cgcgtttggg
     3721 agatggcaat cgagcccata aattattggc agagcagtta aagacatcca ccttgccaaa
     3781 tctttggtgt agccatcctc cttttcagat agatggtaat tttggtgcta ctagtggcat
     3841 ggcagaaatg ttactccagt ctcatgcagc ttatctggta cctctagctg ccctacctga
     3901 tgcttggtca acaggttctg tttcaggctt aatggcacgt ggacattttg aagtgagcat
     3961 gagctgggaa gataaaaaac tcttacagtt gaccatttta tcaaggagtg gaggagattt
     4021 gcgagtttct tatccagata ttgagaagag tgtgattaaa atgaatcaag aaaaaataaa
     4081 agcgaaatgc atggggaaag attgtatttc ggtggcaaca gcagaaggtg atcttgttca
     4141 attttatttt taagaagatg ttataaggca gtaatttgaa actgcctttt aataaggatt
     4201 taagaatata agcagttttc aactagttga aaaagcgtta taatgataat aggaagtaat
     4261 actcaatgaa aatcaaagag cacaaacaag gaagctagcc gcaggttgct caaaacagtg
     4321 ttttgaggtt gcagatggaa gctgacgtgg tttgaagaga gattttcgag gagtataatt
     4381 tgtttgatag agggtgggtc tgatggctta tattgagatg aaacactgtt acaagcgtta
     4441 tcaggttggg gacacggaga ttgtggccaa tcgtgatgtg aattttgaga ttgaaaaggg
     4501 ggagctggtt attatccttg gtgcttcagg tgcaggcaag tcaacagtgc ttaaccttct
     4561 tgggggaatg gataccaatg atgaagggga aatctggatt gatggtgtta atattgcgga
     4621 ttatagttcc caccagcgca ccaattaccg tagaaatgat gtggggtttg tttttcagtt
     4681 ttataatcta gtttctaatc tgacagctaa ggaaaatgtg gaactggctt ctgaaattgt
     4741 gacagatgtc ttgaatcctg atcaggtctt gacagatgta ggtctggctc atcgtctaaa
     4801 taactttcca gcccagcttt ctggagggga gcaacagcga gtctccattg cacgcgcggt
     4861 agccaaaaat cctaaaattc ttctttgtga tgaacctact ggagccttgg attatcagac
     4921 gggcaagcag gttttgaaaa ttctccaaga tatgtctcgt caaaagggag cgacggtgat
     4981 catcgtgact cataatggag ctttggcgcc cattgctgat cgcgtgattc atatgcacga
     5041 tgccagtgtc aaggatgtgg tgctcaacca gcatcctcag gatattgaca gtttggagta
     5101 ctagtatgat caagcgaaaa acttattgga aggacttaat tcagtccttc acaggctcca
     5161 aggggcgttt tttatccatc ttgatcctga tgatgttggg atctctagcc ttagtaggcc
     5221 tcaaagtaac cagtcccaac atggaggcga cagctaatgc ttatttaaca actgctcaaa
     5281 ccttggattt ggcagtcatg tctaactatg gcttggatca agcagaccaa gaagaactaa
     5341 aacagacgga gggcgcagag gtcgagtttg gctatttgac agatgtgact atggataatg
     5401 ggcaggatgc cattcggctg tactccaaac cagagcgaat ttcaaccttt cagctaagaa
     5461 agggacgact tcctcagtca gacaaggaaa tcgctttggc cactcatttg caaggccaat
     5521 gcagcgtggg acaggagatt agttttaaag aaaaagaaga gggtcattcc tctttaaaag
     5581 accatactta taccattact ggttttgtgg attcggctga aatcctctcc cagcgagata
     5641 tgggctacgc aggaagtgga agtgggactc tgacagccta tggggtgatt ttacctagtc
     5701 agtttgatca gaaagtctac aatatagctc gtttgaaata tcaagattta gcaggtttaa
     5761 atgccttttc atcagcttat gaagaaaaat ccaagcaaca tcaggaagac cttgaacaaa
     5821 ctttatcaga taatggcaag gtacgtctgc aacttttgaa aaaagaagga caagagtctc
     5881 tagacaaggg gcaagagacc cttgacaagg ctcagactaa tttgcaggaa ggcaagcgtc
     5941 gtttagcagc tgctcaagct cgtatacagg ctcaagaaag tcaactagcc ttgtttcctc
     6001 aagttcagag agagcaggct agtgctcaac ttacccaagc caagcaggaa ttgggcaagg
     6061 aagaagacaa actaaagcaa gctgaacaaa atctagccca agaaaaggaa aaattagaaa
     6121 aacatcagca agtcttggac gatttggcgg agccaaggta tcaggtctat aatcgtcaga
     6181 ccatgccagg tggtcagggc tatcttatgt atagcaatgc ttcatccagt attcgagcag
     6241 tgggcaatat ctttcctgtg gtactttatg ccgtagcagc catggtgacc tttacgacca
     6301 tgactcgctt tgtagacgaa gagcgaactc atgcagggat ttttaaggcc ttgggttacc
     6361 gtagtaagga tattatcgcc aagtttctcc tttatggact agtagctggg actgtcggaa
     6421 cggctctagg tagtatactt ggtcattatt tgctagccag tgtaatttca agtgtcatta
     6481 caaaaggcat ggtggtggga gaaacccaga ttcagttcta ttggacctat agcttactag
     6541 ctcttgtctt gagctggttg gcgagtgtgt taccagccta tctggtggct tggagggaac
     6601 ttcatgccga agcagcccag cttctacttc ctaaacctcc tgtcaaagga gctaaaatct
     6661 tattggagcg tatcggtttt atctggcgtc gtctcagttt tactcataag gtaacagccc
     6721 gcaacatctt tcgttataag cagagaatgt tgatgacaat ctttggtgtg gcaggttctg
     6781 tagctctgct ctttgcaggt ttgggaatcc aatcttctgt agcaggagtt ccgtctaaac
     6841 agtttcaaca aatccaacag tatcagatgc ttgtctctga aaatcctagt gcgaccgatc
     6901 aggacaaggt agagctagca gaagtgttga aagggcagga gatactagcc taccagaaaa
     6961 tctattctaa aacgctagac aaggatttca aaggcaaggc tggtcttcaa aacattactc
     7021 ttatgatgat agagaaggaa gatttgactc cctttatcca tcttcaacat catcagcagg
     7081 agctgacatt aaaagatggc atcgttatta cagctaaact cgcccagctg gcaggtgtca
     7141 aggttgggca gactttagaa attgaaggta aggaactaaa ggtcgctgct attactgaga
     7201 actacgttgg tcactttatt tatatgagtc aggctagcta tgagcaactt tacggacagc
     7261 taccccaagc caacacttat ctggtctcat taagggatac cagtgcaact agtatcgaaa
     7321 gtcaggcggg cttgcttatg agtcaatctg cggtgtccag cgttgtccaa aatgcttcag
     7381 ccattcgact cttcgactct gtcgctagct cactcaatca gaccatgacc atcttggtca
     7441 tcgtatcggt tctattagct attgtcatcc tttacaatct gaccaatatc aacgtagctg
     7501 agagaatccg tgaactctcc actaccaagg ttcttggttt tcataataat gaagtcaccc
     7561 tctacattta ccgtgagacg attgtgctat cccttgtggg aatcgtactt ggtctggtag
     7621 ctggtttcta tttacaccaa tttttgattc aaatgatttc gcctgcgact attctctttt
     7681 atccgcaggt aggctgggaa gtctatgtaa tcccagtggc agcagtaagc atcattttga
     7741 ccttgcttgg tttcttcgtc aattattatc tgagaaaggt tgatatgtta gaagccctga
     7801 aatctgtaga gtaaggtagt tatttttagc tgattgaact tctatttact aatattcaaa
     7861 aatcctccgt ttcaaagagc agggaactct ttgtgacaga ggattttttc tatagggctt
     7921 tagcagctgc aattgcggct tcgaagtttg gctcagaatt gatattatcc acgtattcaa
     7981 cgtagcgaat cgtattgtca gtatcgagga caaagactgc gcgtgctaat aggtgccatt
     8041 cgttgatcaa gagggcataa tcgcgcccga aagaatggtc aaagtagtct gaaagcataa
     8101 tggcattgtc aaggccttca gcaccgcacc aacgtttttg agcaaaaggt aggtccattg
     8161 aaacagtcaa tacgaccgtg ttgtccagtc cagccaattc ttcattaaaa cgacgtgttt
     8221 gagttgagca gatgcctgta tcgatagaag gaacgacact caagactttt ttcttgccat
     8281 caaaatcagc cagagatttt ttagaaagat ctgttgtagt aagagaaaaa tcaagcgcct
     8341 tgtcgccgac ttgtagttgt ttacctgtaa agctcacagg atttccgaga aaagttacca
     8401 taggatactc caatcttttt tcttccattg tatctgaaac agtcagaatt ttccaatgat
     8461 ttgaccggaa atgtgggcat agaaaaaacg ccagctcaca tgagaatgac gtttttcaga
     8521 ggcttatttt gccaatcctt cagcaatctt gtcaaggttg tatttcatca tgctgtagta
     8581 gctgtcgcct tctttacctt gttctgcgat agagtcagta aagatttgtg cgtagattgg
     8641 gatgtttgtg tcttgagaaa cagttttcat tggacggtca tccacacttg attctacaaa
     8701 gagtgatgga acttttgttt ggcgaagttt ttcaaccaag gtcttgattt gttcaggagt
     8761 tccttcttct tcagtattga tttcccagat gtaggcactt gggacaccat aggctttaga
     8821 gaagtatttg aatgctcctt cgctggttac aatgagtttc ttttcagcag ggatcttatt
     8881 aaatttatcc ttactttctt tatcaagttt gtctaactta tcagtatatt ctttgagatt
     8941 tttttcatag aattctttat tgttagggtc tttggcgctc aattgtttgg cgatattttt
     9001 agcaaaaata ataccgtttt caaggttaag ccaagcgtgt gggtcttctt ttcctttttc
     9061 attttgacct tcaaggtaga taacatcaac gccgtcgctg actgcgaagt agtctttgtt
     9121 ttcagttttc ttggcatttt ctaccaattt tgtaaaccaa gcattgccac ctgtttcaag
     9181 gttgataccg ttatagaaaa tcaaatcagc ctcagaagtt ttcttaacgt cttcaggaag
     9241 tggttcgtat tcgtgtgggt cttgcccaat cggaacgata ctatgaaggt caattttgtc
     9301 accagcaata tttttagtaa tatcagcgat gattgagttt gtagcaacaa cttttagttt
     9361 ttgaccagaa gttgtatctt tttttccgct agcacatgct acaagaatga ttgcagaaag
     9421 aaagagaacg agtaatgtac ctaatttttt cattagatcc tccaatttat tagggctttg
     9481 ccccttattt taacaaatgt ttatttttca gtttcaaata tcgttgtttg ggagcgataa
     9541 agaagctaat gagaaagaaa ctagcagctg taagcacgat actagaacct gccgcaacat
     9601 taaaactata gccaataaag agtcccaaaa ctgaagcagt agctccgaag gttgaggaaa
     9661 ggaaaatcat gcttttcaga ctattagcat acagataagc agttgcagct ggggtaatca
     9721 gcatggctac aatcaggata gttccgacac tttgcatggc tgtcacagac acgagagtca
     9781 ggagtaccat gagaaggtag tgatagaaat tgacaggcat tcccatggct ttagccaaga
     9841 gttcatcaaa ggaagttatc aagagttgct tgaagaaaat ccagattaac aagaggatgg
     9901 ctgcccccac acccatagta ataaacatat ccgtatcttg gacggccagg atattaccaa
     9961 aaaggatatg gaaaaggtca gttgaacttt tagcgacacc aatcaagatg ataccgaggg
    10021 ctaagaaaga agaaaaggta atgccgatgg cggtatcgct tttgataatc gagtttcctt
    10081 tgatgtaggt aatgatgatg gcagctagca atccaaagac aatggctccg ataaagaagt
    10141 caaggcccaa gatgaaggag agggctacac ctggtaagac agcatgtgaa atggcatctc
    10201 ccatgagtga catcccgcgt agaataatga aacatcccac ggctccagct acaatcccga
    10261 cgacaatagc tgttatcaag gcattttgta ggaaatggaa tttttgcaat ccatcgataa
    10321 attctgcaat cataggtcac ctccattgaa aaagagttga ttaccgtaag cttcttttag
    10381 attggtttcg gtaaaagttt cttttgttgg accaaaggca atcacttctc gattgacaag
    10441 taagacttga tcgaagtagt ggggaatctt gctgaggtcg tggtgaacga tgagaaccgt
    10501 cttcccagct tttttcaaat ctctcagcgt attcatgatg atttcctcac tgacagagtc
    10561 aatcccagca aagggttcat ccaagaggat atagtcggct tcctgcacca aacatctggc
    10621 aatcaagacc cgctggaatt gacctccaga cagttgacta atttgacgtt cagcgtagtc
    10681 agctaggccg acgatttcaa gggcctcttg cactttcttc caatgtttag cctttaaact
    10741 tcgaaagaga ggaatagagg gaaatagtcc taacgagacg cattccttga ccttgatggg
    10801 aaagttgtag tcgatattga ttttttgttc gacataggca attcggtgta aggatttttt
    10861 aacttccttg tcatcgagaa atgcctgacc ttgatgtggg ataattccca acataccttt
    10921 taatagtgtt gatttcccag cgccgtttgg accaatgatg ccggtaattg ttggtccatg
    10981 gagcactagt gaaatatcct taagtgccaa cgtttctttg taggagacac tgaggttttc
    11041 gatacgtatc ataaacttgt attcctcctg tctcttaata tacattaaaa aaaaaattaa
    11101 gtcaagttaa tttttgaaaa aatt
//
LOCUS       DAVKMJ010000055        11121 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000055 DAVKMJ010000000
VERSION     DAVKMJ010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11121
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.055"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            123..523
                     /locus_tag="VW348_001835"
                     /pseudo
     CDS             123..523
                     /locus_tag="VW348_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            582..1256
                     /locus_tag="VW348_001836"
     CDS             582..1256
                     /locus_tag="VW348_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloramphenicol acetyltransferase"
                     /protein_id="HEU9746696.1"
                     /translation="MLHPIFIIRRSWDGIFHLSEWKRNEEFDFFNKMDVPYLSMSSRI
                     EVTQAINFHKKHSISLYAIISWCVMSAINSIPELLMDTDGKIVWQYNQRGCSFTTLTS
                     EDKLNFSSFTMGDNLIEFVSAFNINKQKAEEGQKPNIDKNNIAYLSCVPWIDFLHVST
                     PMNLSKIDTVPRITWGKVIQENQRYFCTVNLQINHGMGDGLHVSNFFVLLQRFVNKIN
                     EYFQKK"
     gene            1324..2961
                     /locus_tag="VW348_001837"
     CDS             1324..2961
                     /locus_tag="VW348_001837"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEU9746697.1"
                     /translation="MSIFIGGAWPYANGSLHIGHAAALLPGDILARYYRQKGEEVLYV
                     SGSDCNGTPISIRAKKENKSVKEIADFYHKEFKETFEKLGFTYDLYSRTDSPLHHEIV
                     QELFLQLYEKKFLYTKKIKQLYCTFDNQFLPDRFVEGKCPNCGTHSRGDQCDNCSAIL
                     DPIDLVDKRCSICSNEPEVRETEHFYYVFSEFQNLLETYLNDAEETVRWRKNAINLTK
                     RYLREGLPDRAVTRDLPNGIPVPIDGFRDKKIYVWFEAVAGYYTASVDWAQKLQNNIT
                     DFWNNRTKSYYVHGKDNIPFHTIIWPAILSGLEIEPLPEYIISSEYLTLENKKISTSN
                     NWAIWLNDIIKKYDADSIRYFLTINAPEMKDANFSWREFIYSHNSELLGSYGNFINRT
                     LKFIEKYFESEIPTKYLEGEILYNLKELYTTVGNLVESGHMKQALEEIFEYIRSANKF
                     YDDMKPWALRESDIEKCKEVLATCVIIILNLGQMLNPFIPFSGKKIEDMFKTKLNTWN
                     YISNLPNKLSDVSMLFDRIDLKKIDEEVLELQQTSSR"
     gene            3062..3829
                     /locus_tag="VW348_001838"
     CDS             3062..3829
                     /locus_tag="VW348_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HEU9746698.1"
                     /translation="MNNLTLLKEYNFRDLGNHLTQTGQKIKPKTLFRSSKLFGISKID
                     VDLLQSYGITKVIDFRSANEIKKAPDPDIKNIKNIVIPIFYNDDSELTEFPIEFFNKS
                     DAGFQHMIKTYDQMINQKQSKLGYKKFFKLLLSHPKDESLLFHCSMGKDRTGIASLFL
                     LYILGVDMNDIFHDYLLSNKYLINVRKENIEYVNNHSGNVILMHNLLSLSSAKEEYIN
                     RVLNVLDKEYGGILRYINTELGISSQEIEELKDRYLF"
     gene            4846..5505
                     /locus_tag="VW348_001839"
                     /pseudo
     CDS             4846..5505
                     /locus_tag="VW348_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(5544..6971)
                     /locus_tag="VW348_001840"
     CDS             complement(5544..6971)
                     /locus_tag="VW348_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEU9746699.1"
                     /translation="MKTTNKVAIYVRVSTTSQVEEGYSIDEQKDKLEAYCKIKDWKIY
                     DVYVDGGFSGANTQRPELERLISDVKRKKVDIVLVYKLDRLSRSQKDTLFLIEDVFAK
                     NDVAFISLQENFDTSTPFGKASIGMLSVFAQLEREQIKERMMLGKEGRAKNGKSMSWT
                     TIPFGYDYSKETGVLSVNPTQALIVNRIFTEYLNGKPVVKIIRDLNAEGHVGRKRPWG
                     ETITKYLLKNETYLGKVKYKDKVYEGQHEPIITQELFDLVQLEVERRQISAYEKYNNP
                     RPFRAKYMLSGLMKCGYCGASLGLRYTRKDKNGISHHKYQCRNRHSKDLEKRCESGWY
                     SKEELERIVIKELERIKFDPKYKNETLAKKEETIKVEEIKKQLERINNQVSKLTELYL
                     DEIITRKELDEKNDKIKTERQFLEEQLENQKSNVLSIRKRKLTRLLKDFDVEKLSYED
                     ASKIVKNIIKEIIVTKDGMSITLDF"
     gene            complement(7139..7339)
                     /locus_tag="VW348_001841"
     CDS             complement(7139..7339)
                     /locus_tag="VW348_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746700.1"
                     /translation="MSNESRPMEVIKHNLDCKCHRRREWIRVNDKWHAIEFSVDDPNE
                     PPMTEEEKANVALILQQHLSKE"
     gene            complement(7341..8132)
                     /locus_tag="VW348_001842"
     CDS             complement(7341..8132)
                     /locus_tag="VW348_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HEU9746701.1"
                     /translation="MARGRGKLTPQDKEDMKVFSANLNSILSDRNCKQAELSRATGIP
                     PSTLTGYVKGTSLPIPGNVQKIADFFGVPKSVLDPRFITNNFMVNDSSSNTPQIQTIY
                     DELEPPRQGKVLNYAKRQLKEQKNEEETKINEVSEAIRLYSYDYYDHPASAGTGQYLN
                     DVRVERIELPVDVDADFVIPIKGDSMEPDYHDGDLVFIQTSVDLNDGVIGVFNYNGDA
                     YIKQLVIDEDQAYLHSLNPEYKDMPITPDTDFRIIGEVVDLYREK"
     gene            8305..8580
                     /locus_tag="VW348_001843"
     CDS             8305..8580
                     /locus_tag="VW348_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015973618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746702.1"
                     /translation="MNTLNEKAINIFKAVAKETLIQGTYEENFLYSQLEAFCTNCRQF
                     AFGWTELAEEIERQERYLLDSGFTQEEIDDIRFDAAFAGMLDKLNVA"
     gene            8655..8822
                     /locus_tag="VW348_001844"
     CDS             8655..8822
                     /locus_tag="VW348_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001005822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746703.1"
                     /translation="MNESFLTILGISMIASFITNLIAYLAGKHHLKKKIKNHKMWFDS
                     EIERIKKKYHL"
     gene            complement(8813..9262)
                     /locus_tag="VW348_001845"
     CDS             complement(8813..9262)
                     /locus_tag="VW348_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746704.1"
                     /translation="MNNFSFIETLAIAAIPAFVSGMWSYIAAKGNSKHEIDKINIAHS
                     QELENVENQFKQDMEKMQKQHSQELYSLQQTHELRLLELEKVSQLDTQTDQGLKINDL
                     IFKAISGEISADVAIKNMSTLSHFANKQQPSDLQKQFVKKLSKKNHK"
     gene            9461..9631
                     /locus_tag="VW348_001846"
     CDS             9461..9631
                     /locus_tag="VW348_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746705.1"
                     /translation="MKEKLNEFLKFRSQFTKREWFEINQTVEARLNQKADHLKLDDVD
                     LEIISKRLGRSI"
     gene            complement(9856..10062)
                     /locus_tag="VW348_001847"
     CDS             complement(9856..10062)
                     /locus_tag="VW348_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746706.1"
                     /translation="MTDYQLEASLIVLGKEFDRTKKNGKESFSVHVSFFDGLDANQHL
                     QEFARQYPVKIDRSNSDQITFLIK"
     gene            10135..10362
                     /locus_tag="VW348_001848"
     CDS             10135..10362
                     /locus_tag="VW348_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9746707.1"
                     /translation="MPKMTLRAIRTNYNLSAKEVADKLNIHQQTLLKYEHDSSKIPMD
                     LLDKLARLYNVEKDFIFLGKKYELNHNLGEV"
     gene            10405..10767
                     /locus_tag="VW348_001849"
     CDS             10405..10767
                     /locus_tag="VW348_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9746708.1"
                     /translation="MQYIIRNTHGNYTSLNNAYAQDKRLKATTIGILTVILMNKSDWV
                     VYPDEIARRLGISRRTVDEHFKLLEKAGYLRVYRLGLGRGKGVTVYRFFSDMPISDDY
                     FEYLKTNLEKELSTDNGV"
BASE COUNT         3650 a         1756 c         2051 g         3664 t
ORIGIN      
        1 tatgacaata ttttaaataa aatgattgac aacgctttct tttattgata taatgaaaat
       61 gtaatatgta tcaaattgat caatcaacta tcttgtttat cacttcttag gaggacgata
      121 tcatgaaaag aagaaaaata tattcctttt ttgcgtagtt acaattgcat ctagtttgtt
      181 tctccctaca gttttagcta gacagattgg aaattatgat ttaacgttgc cgcgttgggg
      241 ttcggataca actagtgagc ttgagaaaga aaacgcctct gctggaatta ataatgacag
      301 cactggtggc ggtaaaaggt taaatacctc tattcgtagc gcctatagtg ggtcagatat
      361 taccccggta tattcattgg ggtctggctc taggattgtc atgtactata atggaggtgg
      421 tgacaattat attggttctg gtactagatt agctatggcg ccacaatttg gaaatcatgt
      481 aagaattcat acttcaggtt cttggagtcc agattcttat taacttactt gtcagagtaa
      541 gccttaaaga tggttgattg tgggtgtagc atgaaaaaag aatgctacac cctattttta
      601 ttataaggag gagttgggat ggaatttttc atttatcaga gtggaaaagg aatgaagaat
      661 ttgacttttt caataaaatg gatgttcctt atttatctat gagttcacga atagaagtaa
      721 cgcaggctat caattttcat aaaaaacatt cgatatcact ttatgccata atatcgtggt
      781 gtgttatgag tgcaataaat tctattccag aattactaat ggataccgac ggaaagattg
      841 tctggcaata caatcaaaga ggttgttctt tcactaccct tacatcggaa gataagctta
      901 atttttcttc atttacgatg ggagataatt taattgaatt tgtttctgcg ttcaacataa
      961 ataaacagaa ggcagaagaa gggcaaaaac caaatattga caagaataac attgcttatc
     1021 tttcttgtgt tccatggatt gattttttac atgtaagcac tcctatgaat ctttcaaaaa
     1081 ttgatacagt tcctcgaata acgtggggaa aagttattca agagaaccaa agatattttt
     1141 gtacagtgaa tttacaaatt aatcatggaa tgggagatgg attacacgta tctaattttt
     1201 ttgtgttatt gcaaaggttt gtaaataaaa taaatgaata ttttcaaaaa aagtaatgat
     1261 tgaaaagata ttgcatttaa ataatgttat aataaaaata aagaatttaa ggagaaatac
     1321 aatatgtcaa tttttattgg aggagcatgg ccatatgcaa acggttcgtt acatattggt
     1381 cacgcggcag cgcttttacc gggggatatt cttgcaagat actatcgtca gaagggagag
     1441 gaagttttat atgtttctgg aagtgattgt aatggaaccc ctatttctat cagagctaaa
     1501 aaagaaaata agtctgtgaa agaaattgct gatttttatc ataaggaatt taaagaaact
     1561 tttgaaaaat taggttttac atatgacttg tactcgcgaa cagattctcc actacatcat
     1621 gagatagtac aagaattatt tttgcaatta tacgagaaga aatttttgta tacaaaaaaa
     1681 attaaacaac tctattgtac atttgataat caattcttac ctgataggtt cgttgaagga
     1741 aaatgcccga attgtggaac ccattcaaga ggagatcaat gtgataattg ctcagcaatt
     1801 ttagatccta tagatttagt tgataaaaga tgttctattt gttccaatga accagaagtt
     1861 cgtgagacag aacactttta ttatgttttt agtgagtttc aaaatttgtt agagacttac
     1921 ttaaatgatg ctgaagaaac agtgagatgg cgaaaaaatg caataaatct aactaaaagg
     1981 tatttacggg aaggtttacc tgatcgagct gttactcgtg atctaccaaa tgggattcca
     2041 gttcccattg atggttttag agataaaaaa atatatgtct ggtttgaagc ggtagcaggt
     2101 tactacacag caagtgttga ttgggcgcaa aaacttcaaa ataatattac tgatttttgg
     2161 aacaatcgga caaagtcata ttatgttcat ggaaaagata acatcccatt tcatactatt
     2221 atttggccgg caatactctc aggtttagaa atagagcctc ttccagagta tattatttct
     2281 agtgaatatt taacgttaga aaacaaaaaa atatcaacaa gtaataattg ggctatatgg
     2341 cttaacgata tcataaaaaa atatgatgct gattcaatcc gatacttcct aacaataaat
     2401 gctcctgaga tgaaagatgc aaatttttct tggagagaat ttatttatag tcataactca
     2461 gaattattag gatcgtacgg taattttatc aataggactc taaagtttat tgaaaagtat
     2521 tttgaatctg aaatacccac taaatatctc gaaggagaaa ttttatataa tttgaaagaa
     2581 ttatatacaa cagtaggtaa tttagttgag agcgggcata tgaaacaggc attagaagaa
     2641 atttttgaat atattagatc ggctaataaa ttctatgatg atatgaaacc gtgggcattg
     2701 cgagagtccg atattgaaaa atgtaaagaa gtcttagcta cttgtgtaat cattatactt
     2761 aatttaggac aaatgttaaa tccattcatt cctttttctg gtaaaaagat tgaggatatg
     2821 tttaaaacaa agctaaatac ttggaattat atttcaaacc ttcctaacaa gctatcagat
     2881 gtatcaatgt tgtttgatag gattgatttg aaaaaaattg acgaggaagt tttagaattg
     2941 caacaaacat ccagtagata attcaaaaat actcgaaagt agcctttttt aatttaaatt
     3001 aacaaccgga gatgttgaat aaaataaaga tggttttttg agcatattat ggagaaaagc
     3061 attgaataat ctaactttac taaaagaata taattttaga gatcttggaa accacctcac
     3121 tcaaacagga caaaaaataa aacctaaaac attattccgt tcaagtaaac tatttggaat
     3181 ctctaaaatt gatgtcgatt tgttacagag ctatggaata acaaaagtca ttgactttcg
     3241 atcagcgaat gaaataaaaa aagctccaga tccagatata aaaaatataa aaaatatagt
     3301 aattccaata ttctataatg atgattcaga gttgacagaa ttcccaatag aattttttaa
     3361 caaatcagat gcaggttttc aacatatgat aaaaacttat gatcaaatga tcaatcaaaa
     3421 acagagtaaa cttggttaca agaaattctt taaattatta ctaagtcatc caaaagatga
     3481 atctcttttg tttcattgtt caatggggaa ggatcgaaca ggaatagcta gcttgttctt
     3541 gctttatata ttgggagtag atatgaacga tatttttcat gattacttac tatctaacaa
     3601 gtatttaata aatgtgagaa aagaaaatat tgaatatgta aataaccata gtgggaatgt
     3661 aatattgatg cataatttac tttcactcag ttcagcaaaa gaagaatata ttaatcgagt
     3721 attgaatgtc cttgataaag aatatggagg aatacttaga tatattaata cagaactagg
     3781 aataagtagt caagaaattg aggaattgaa agatagatat cttttttaga atagtaagta
     3841 ctaaaaatga atatataaca gtgcgaacgg cggttttgtt tttgtctaat tctactaatt
     3901 taacataagc aaaaacggat tgttttctat gtaagtcctt aactaaattg atggaaagca
     3961 cgttaaatta tgtgcaaaat gcgtacaaaa tagtgtttat caaatgtaaa atttcctact
     4021 tgtcatcaaa gttcaacaaa tgtaggttgt ttggttattt gggtagattt ctggacttat
     4081 cgttggttgt agagacataa tgttgcagtt aaagcttaga gaataatctc cgtatttttg
     4141 ttaggcaatt taaaagttaa gacaaagtga gtttgtctct taattcaact caccacaaac
     4201 acatcacctt tttattataa cttccgacca atttttttga agagaaaaat gaaaaaacac
     4261 caactgtgca gggtagctga caaggcttct agcttccatt tattgaaacc aaatcaatct
     4321 gttatgagat aatagcagtt gcagaagctg actactttga gaagttaaat gaggtttatt
     4381 atcaagaata cttcatgaat atagttataa gggagggggt agttgaaaga attgactcat
     4441 ctgttaaaat aaaaatggaa ataataacat cataatagtg tgacttagta tttttcagca
     4501 tcttggaagt aggtaaatga tattaaaatt atactgcata gtaaaggata gtaatgagga
     4561 atttaatatc ttcctgtcaa tatcttcagt tattaaagta tttttatatt gggataactt
     4621 cgtttgctga aatctatagt ttatccaatt ataaatttat atgttcttcg tcataattct
     4681 ttgtacttga gtaatttagc ttacttacag ataaaataca agatggcata gttttagtag
     4741 cttttttcat atggtttgta atgatggtaa attttcttaa ctttactgta gtatgctaca
     4801 atttttgttg atattataac ttgagtgaaa cgaaaggagt gatttataaa aatgataaca
     4861 gtagagcatc ttcagaaaaa ttttgtgaaa acaataaagg aacctggctt aaagggagct
     4921 tttcgctctt tttttcatcc caagagacaa gtctttgaag ctgttaaaga tttatcattt
     4981 gaggtgccca aaggacaaat tttaggcttt attggcgcaa atggagcggg gaaatcaaca
     5041 actatcaaga tgttgacggg gattttgaaa ccaacatcag gtttttgtcg tatcaatgga
     5101 aagattcctc aagagaaccg tcaaggctat gttaaagata ttggtgtagt ttttgggcag
     5161 cgaactcaac tttggtggga tttggctttg taggagactt actcggtttt aaaggaaatt
     5221 tatgatgttc ctgatgcggt ctttcaaaaa cgcatggatt ttctaaatga agttttagat
     5281 ttgaaggaat ttattcaaga tcctgtcaga actctatctc taggtcaacg tatgagggcg
     5341 gatattgcgg cctccttatt gcataatccg aaagttcttt tcctagatga gcctactatt
     5401 ggtttagatg tttcggtcaa ggataatatt cgacgtgcca ttacacagat taatcaagaa
     5461 gaagagacga ccatactttt aacgacccac gatttaggtg atattaatta ctttgactaa
     5521 aatacagaaa tacgctagac cctttaaaaa tctagcgtta tcgacatgcc gtcttttgta
     5581 acaataattt cttttatgat atttttgaca atttttgaag catcttcgta gcttaatttt
     5641 tcaacatcga agtcctttag tagccgtgtt agctttctct ttcggatgct cagaacattc
     5701 gatttttgat tttcgagctg ttcttccagg aattgccttt ctgttttgat tttatcattt
     5761 ttctcgtcca actctttccg agtgatgatt tcgtccaagt acaattctgt taattttgag
     5821 acttgattat ttatccgttc gagttgtttc tttatctcct cgaccttgat agtctcttct
     5881 ttcttagcga gtgtctcatt tttatatttt ggatcaaatt taattctttc aagttccttg
     5941 attacaatcc tttcaagttc ctctttagag taccaccctg attcgcatct tttttctaaa
     6001 tctttgctgt gtcggttcct gcattggtat ttatgatgag agattccatt cttgtctttt
     6061 cttgtatatc tcagaccaag tgaagcacca caatatccgc atttcattaa tccagaaagc
     6121 atatactttg ccctgaacgg ccttggattg ttatattttt cataggctga aatctgcctt
     6181 ctttcgactt caagctggac taagtcaaac aattcttgag tgataattgg ttcatgctgc
     6241 ccctcgtata ccttatcttt gtactttact tttcccaaat aggtttcatt tttcagcaag
     6301 tatttcgtga ttgtttcgcc ccaaggtctt tttcttccaa cgtgaccttc agcatttaag
     6361 tctctgatga tcttgactac tggcttaccg ttcaagtatt ccgtgaaaat acggttgaca
     6421 atgagcgctt gggtcggatt cactgataag acgccagttt cttttgagta atcatagccg
     6481 aatggtattg tcgtccatga catggatttt ccattctttg cccgtccttc ttttcctaac
     6541 atcatacgct ctttaatctg ctcacgctcc agctgagcga atactgatag cataccgatt
     6601 gaagccttgc cgaaaggcgt agaagtgtca aagttttctt gcaagctgat aaatgccaca
     6661 tcgtttttag caaacacatc ttcaatcaga aacagagtat ctttctggct acgactgagg
     6721 cggtctagct tgtagactag cactatatcg actttcttgc gcttcacgtc tgagattaaa
     6781 cgctccaatt caggtctttg agtgttagca cctgagaaac caccatcaac gtagacatcg
     6841 tagattttcc agtctttgat tttacagtag gcttcaagct tgtctttctg ctcatcgata
     6901 gagtaaccct cttccacctg cgaagtagtg gacaccctga cgtagattgc gactttattc
     6961 gttgttttca ttgaatttgt accccttttt tgataaaata ggtacaagaa aacgtctcaa
     7021 aaggtaatat cttttgaaaa gtttttcttg ccactagcct cacgctcgga gtcgccaaac
     7081 tttgagagcg tggggctttt tttgtttgca attatttcca ttttggaaac agttggtttt
     7141 attctttcga taagtgttgt tgaagaatta aggccacgtt ggctttctct tcctctgtca
     7201 taggaggttc gtttggatcg tctaccgaaa actcgatagc atgccattta tcatttactc
     7261 taatccactc tcttcgtctg tggcatttgc aatctaggtt gtgtttaatc acttccatcg
     7321 gtctactttc gttactcatg ttatttctcc ctatacaaat ccacgacttc gccgataatt
     7381 cggaagtcgg tgtctggtgt aattggcata tctttatatt cagggtttag gctatgtagg
     7441 taagcctggt cttcatcaat aacaagctgc ttgatataag catcgccgtt gtagttgaat
     7501 actccgataa ctccgtcatt caaatctaca cttgtctgaa tgaataccag gtcaccatcg
     7561 tggtagtcag gctccatgga gtcacctttg atggggatga caaagtcagc atcaacatct
     7621 actggtaact caatccgttc cactcgtaca tcattcaaat actggcctgt acctgcggaa
     7681 gctgggtggt cgtagtagtc gtaactgtag agccgaatag cttctgatac ttcgtttatc
     7741 ttcgtttctt cttcgttttt ttgctctttc agttgcctct ttgcataatt caggactttg
     7801 ccctgtctag gtggttctag ttcgtcgtag atggtttgaa tttggggagt attagaagaa
     7861 gagtcattga ccatgaaatt attagttata aatctaggat ctaatacaga tttaggaact
     7921 ccaaaaaaat ctgcaatttt ttgaacatta ccagggattg gcaaagaagt tccttttaca
     7981 taccctgtca atgtactagg cggtattcct gttgctcgag acagctcagc ttgtttacaa
     8041 tttctatcag ataaaattga gttaagattt gcagaaaaga ctttcatatc ctctttatct
     8101 tgaggagtta atttccctcg tcctcttgcc atatttttac ctcctatctt ctttactata
     8161 taataccgtt tattttcgat tttgtaaata aaaaattcga aaaaattacg aaaaaattcg
     8221 aaaaatcatt gacatacgat ttaaatcgta gtataatata atcaagctta aggaaataac
     8281 aaaaacaaac cggagggaaa caccatgaac acattaaacg agaaagcaat caacatcttt
     8341 aaagcagtag ctaaggaaac tttaatccaa ggcacttacg aggaaaactt cctttacagc
     8401 cagcttgaag cattctgtac taactgccgt caattcgctt ttggatggac agagttagca
     8461 gaggagattg aacgccaaga gcgttacctt ctcgattctg gtttcactca agaggaaatc
     8521 gatgacattc gttttgatgc agcatttgca ggaatgcttg ataaattaaa tgtagcctga
     8581 ttggtatcac caaggttcga atccttggca ggttgttgct catagagcga aaaaagagag
     8641 aaaggagtag aacgatgaat gaatcttttc ttacgatact aggcatatca atgattgcta
     8701 gttttatcac gaatttaatt gcttacttag ctggtaagca tcatctgaaa aagaaaatta
     8761 aaaaccacaa aatgtggttt gattctgaga tagagcgtat caagaaaaag tatcatttgt
     8821 gatttttctt ggataatttt ttcacaaatt gtttttgaag atcggaaggt tgttgcttgt
     8881 tcgcgaaatg actaagagtg ctcatatttt ttattgctac atctgcagat atttctcctg
     8941 aaatagcttt aaaaattagg tcatttatct ttaagccttg gtcggtttga gtgtctagtt
     9001 gagatacttt ttcaagttca agtaatctta attcgtgagt ttgttgcagc gaataaagtt
     9061 cttgtgagtg ttgcttttgc attttttcca tatcttgttt aaattgattt tcgacatttt
     9121 caagctcttg tgagtgtgca atgttaattt tatcaatttc atgcttgctg tttcctttag
     9181 cagcgatgta agaccacatg ccagaaacaa aggcaggtat ggcagcgatc gcaagtgttt
     9241 ctataaaact aaaattattc ataagatttc tccaatcatt ttattttgat tataccacat
     9301 ttgaaaggta gttagaattg gaagataaaa tcatcgaact tgctgattat ttcatcagcg
     9361 aaaacacaac gtacagagaa gctaaaatag cgtgtgagaa gctatttctt caagtcagtc
     9421 atgagataga actcagggca atggaaagta ggacgagggt atgaaagaaa aactaaacga
     9481 atttctaaaa ttcagaagcc agtttacaaa acgtgaatgg tttgaaatca accaaactgt
     9541 cgaagctcgt ttaaatcaaa aagccgacca cttgaaactg gacgacgtag atttagaaat
     9601 catctctaaa agactaggac gatctatcta aagaaagggt gaaacaaatg gcaactaaca
     9661 gaactatatc agtaaataca tcagagcatg atgtattgtt gacggcaaga aaaaaccacc
     9721 ctgctgtatt cgtcgatgga atgtttctcg acggagttga gcgagtggaa tttaccaatc
     9781 attatctgga gaagtgtgaa gttgttttaa cgtttaacga tagagttgaa accaatccct
     9841 tccctctaaa cgatattact ttattagaaa agttatttgg tcagagttcg aacggtcaat
     9901 ctttacggga tattgtcgtg caaactcttg aagatgctga ttagcatcta aaccatcaaa
     9961 aaaagaaaca tgaacactaa aactttcttt tccgtttttc ttggttctat caaattcttt
    10021 gccaaggaca attagagaag cttctaattg ataatcagtc ataacatcac ctcctttcta
    10081 gctttattat agcagaattg cgaggaacaa atagaaaaat aaggaggtag gaacgtgccg
    10141 aaaatgacat tgagagcaat aagaacaaat tataacttat ctgcaaaaga agttgccgat
    10201 aaacttaaca ttcatcaaca aacactgttg aagtatgagc atgatagttc aaaaattcca
    10261 atggatcttt tagataaact tgctcgacta tacaatgttg aaaaggattt tattttttta
    10321 ggcaaaaaat acgaattaaa tcataatcta ggagaggtgt gaatgaacga gcgagagtta
    10381 tagaaagggg attaaatatg aggtatgcag tatataatca ggaatactca tgggaattac
    10441 acatctttga ataatgctta tgctcaagac aaacgtttaa aggcaacaac gataggtatc
    10501 cttacagtaa tcttgatgaa taagtctgat tgggttgtgt atcctgacga gattgcacga
    10561 cgtctaggaa taagcaggcg caccgtagat gagcacttta agcttttaga gaaagcaggc
    10621 tatctcagag tatatcgctt agggttaggc agaggtaaag gcgtaacggt atatagattt
    10681 ttttcagata tgcctatttc agatgattac tttgagtatc taaaaactaa tcttgagaaa
    10741 gagttatcca cagataacgg agtttaaaaa tacagttgga aaatattgcc atgtgtaaaa
    10801 ttgccatgtg taaaattgcc atgtgtaaaa ttgccatgtg taaaattgcc ctctaataag
    10861 tactaactat acaacaagta ctaactatac aataatctaa gcctaacggc actaacttag
    10921 taataactac taacttacaa caaactaata cttctctaaa aaataaaaga gagaaatttc
    10981 aattttagga ctttgaaaaa taggaaagga gaaaaaatga gaccaagacg atatccgtat
    11041 agtgggaaaa aagagtccac ctttgtaaag gccgaccctg agttagttga aaaactttta
    11101 agaaacacta gttttcttga g
//
LOCUS       DAVKMJ010000056        10761 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000056 DAVKMJ010000000
VERSION     DAVKMJ010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10761
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.056"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(120..1544)
                     /locus_tag="VW348_001850"
     CDS             complement(120..1544)
                     /locus_tag="VW348_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEU9746709.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVAEKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2089..4368)
                     /gene="pulA"
                     /locus_tag="VW348_001851"
     CDS             complement(2089..4368)
                     /gene="pulA"
                     /locus_tag="VW348_001851"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEU9746710.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPYGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4480..6438)
                     /gene="ligA"
                     /locus_tag="VW348_001852"
     CDS             complement(4480..6438)
                     /gene="ligA"
                     /locus_tag="VW348_001852"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEU9746711.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERGNLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6531..7709)
                     /locus_tag="VW348_001853"
     CDS             complement(6531..7709)
                     /locus_tag="VW348_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEU9746712.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGFIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSIHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7789..8652)
                     /locus_tag="VW348_001854"
     CDS             complement(7789..8652)
                     /locus_tag="VW348_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEU9746713.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYFFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAIHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8655..10556)
                     /locus_tag="VW348_001855"
     CDS             complement(8655..10556)
                     /locus_tag="VW348_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEU9746714.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFDDLRRTDKQLR
                     QMELEMGEKSGDELDKLMSDYDHLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSKKTSGNVVLTVENTAI
                     GYDGEVLSQPINVDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYIEKRATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
BASE COUNT         3232 a         2369 c         1911 g         3249 t
ORIGIN      
        1 agctgtacta ttctagtttc aatatactat aataccaaaa agttcgtatt ttttctataa
       61 ttattattat tttatagcaa aaaaataaaa ccaggaaaac aatttcctga ttttacacgt
      121 tatttcacat caaaaacaat ggatttgaca tttgtcatcg cttcaatgct atatttaatt
      181 ccttgcactc cagctccaga acctttgaca ccaaggaatg ggaaattatc tggaccacgc
      241 tgggttttat tattaatgtg gactgtacct acttcaagtt tttcagcaat ttcaaaggct
      301 tttttgaaat catttgtaaa gactgatgat tgaaggccga attcagattc gttggcaaag
      361 gcaatagctt cctctacact agccacacga atgattggta aaacaggacc aaatggctct
      421 tcccatgcca ctttcatatc ttttgtaact tggtcaaaaa gcactggcca gaggagattg
      481 ccctcacgtt tgattggtgt aagagcctga gcctcttttt cttgtgcatc ctcaatcaag
      541 ccccaaatga agtcggctga agcattgtca ataacaggtg taatatcagc attgtcaaat
      601 ggatcaccaa ctgttaattt agaaacttct tcctgaagca aagtagctaa tttctctgct
      661 acactttcga gaacaatgac acgtttaatg gccgtgcaac gttgtcctga gtagctaaag
      721 gctcccgcaa caatttgctt ggcagcatgt tccaaatctg catcttctag tacaagagct
      781 gcatctttcc caccaagttc caacatgata ggacgcatac cagctaaacg accaatacgt
      841 tctccaatag gagttgaacc tgtaaagttg atgaagttga cttctttgtg ctcaatgata
      901 taatccccaa tttctgaacc acgacctgta atggtgttga aaacacctgc cggaatccct
      961 gcttcttcaa atgctttagc caacaagagt ccagaaatgg aaccttgtgt tggtggctta
     1021 aacatgacca cattccctgc aatcaaggca ggtgcaattt tagaagcaga taaattaact
     1081 ggataattaa agggagcaat cgctagcacg ataccaactg gttcacgacg gacaacagcc
     1141 agtttgtttt tacttgctgc ctcaaaacca ccaccttcca ttgcttgtcc agtgatacgg
     1201 agaccttcct cagcagcata acgaatcaag tctgctgtac gcactacttc tccaattgct
     1261 gctttaatcc cttttgctac ttctttggca aggatagtac caatttcttc cttatcgcgt
     1321 tctaaaatag ctgctgtttt atgtaaataa gccgcacgtt caactgctga taaagctcgc
     1381 catgctggca gggctgcacg cgcagcttgc atagcctcat cagcttcagt ctgagtcatg
     1441 gctggaactg tacccaattc ttcttgattg attggtgaat aaatcgtaat ttcttgttca
     1501 gatgatttcc attttccatt tactaaattc tgatatcttg tcaaattctt gtcctcctga
     1561 aaatgattaa gatatatttt accaaatttt cagaaaatca caaccctttt tgcaaaattt
     1621 ttgagattat tttcacaaac ttgatttttc aaagtatact caataaaaat aaaaaaaatc
     1681 cactacgtca aggcgaggct aatgtggttt gaagaaattt tcgaagagcg tgaatgagta
     1741 tcatctatag taaaataaaa aaactgaaca atttggttgg ggacagccaa accaatttct
     1801 cacaatgttt cagaaacaag ggtgtgctac tccaatttca gcctactata actgtcatag
     1861 attgctgaaa caaagtctag gtaaaagtct tcataataaa aagacctcct atcaagtgtt
     1921 caaaaacttt gataggaggt cttgttttgt gaaaatattt atcaaatttt ctatacaagt
     1981 gagctgttag ccaggttctt tctattcttt caatttcaat gaatggattt tttactaata
     2041 ctcataactg ggaatttgtc tgtgtaaaaa tagcgagata gatggtattt ataaaacact
     2101 caagacagct agactaatat catttaaaac attatcttct tttgagcgac tgttggttac
     2161 caacatagct aaatttcctg cattttcaaa ttgatagggt tctgatttag cattcacaac
     2221 caccaagagg tgttctttgc cgtgaacttc atagataagg tagccgctat gttcaatcgc
     2281 agaatgcaca aagacatgat ggtaaatttc atcatagcta gagtaagaaa aggcaccagt
     2341 ttttgtcttc aatcggatga cttgacggat aaactcaata ctgtcttgac gctcattaat
     2401 caagttccag ttcacttggt tcacactgtc aggagcatta tagctattca tcgcacgctc
     2461 tctatcatca tgggtcaact caccattttc accagtcgca accagtttgg tacgaccaaa
     2521 ttcttgaccg atttccataa aggccatccc ctgcatgagc agattcatgg ctgtggcagt
     2581 ttcgaccttg cgcatgattt gctctgaact ttggtctgga tgaagggttg ccaataaatc
     2641 gtgaagattg taattgtcat gggcttctac atagttaagc acctgatttg gatgtgtata
     2701 gcttcctaat tcacgacttc ctaggattgc tttagctaga attggctctg tcgcagcacc
     2761 actgacaaaa cctgacttga tagcaccata aacttctccc cctttgacag catcgcgctg
     2821 attgtcatta aagaaaccaa tatttggcat ctggtaggca ttgtccttct tggccttatc
     2881 ataaggggca agacctgttc ccatatccca tccttctcca tagaggataa tgttggagtc
     2941 gatttcatcc aagctttgac gaatcatctg catggtcttg acatcatgaa tccccatcaa
     3001 gtcaaaacgg aagccgtcaa tattatattc ctgcacccag tatagaagag aatcaatcat
     3061 atacttgcga aacatttcgt gttcactggc tgtttcattt ccaacacccg ttccattctg
     3121 gaaggtacca tatggattca tacgataata gtaatcaggg actgttgttt ggaatggtgc
     3181 atcaacaact gagaaggtat ggttatagac tacatccata atgactccaa tacccgcatc
     3241 gtgataagct tgaaccatca ccttcaaatc acgaatgacc tgagctggat catctggatt
     3301 agttgaaaaa ctagtttctg gcgcgttata gttttgtgga tcataacccc agttgtaggt
     3361 tacatttcca tcctcatcgt attctttatg acggtctgca attggttgca attgaacata
     3421 attgtagccc agcttcttga tgtaatcaaa agcagttgac tggccgtatt ggttaactgt
     3481 tccagcctga gcagcaccca agaaagttcc tcgaagatgt tcatctacac ccgatgtagg
     3541 tgatttagtc aaatcacgaa tatgcatttc acagataact gccttacatg gattttccaa
     3601 gcgccaagta gcctccgaac cgtgcttaac ctcgaagttt tcaacttgct tttctacatg
     3661 gctcagaata gctgaacgtt tgccatcagg gctggtcgcg attgtataag gatcacgtgt
     3721 cagtgtttgg tgatgaggga attggacttg atactgataa gccttaccta ccaaatcttc
     3781 ctcaacatcc aaactccaga caccgattgt attgtcctta tgattataag agtagctatt
     3841 gcctcttttc atctcaaaag tcttccaaac gggtgcatca ttagcagctg attcataaac
     3901 gacaacttgc acttctgtcg ctgtaggtga ccagagggaa aaatgagcct gattgtcctc
     3961 tacacggcaa cccaattctc cttggtaacc ccaatgatgg tcaaaactag cactgttaat
     4021 ggccttatca aaggcaaaag gattttgatt tttatagaaa ggactggcaa tagcaggatt
     4081 ttcagagtaa taaatcctat catcgccttc caaaatccag acctctgtta ataggggata
     4141 gtgattaaaa cggatagaat attctttact agtttgacct gtatgaacca caaaattcaa
     4201 gctttctata acatgtgaac ttgggtgttc aaagctaaat aaagctccaa aataatcttc
     4261 tttgtaggtt agcaaatcaa ttcgttgatc ctgacttttt acaaaggagc aagtgtcata
     4321 ttctccattc ttacgatggt aatgaatgcg catagggtag ttatacattt tttatttttc
     4381 ctttttactt tgtttctatt tcactaataa atttttgtca atctcgtctc aattaacaga
     4441 catagtcata ttctctaaac tctgttttta aacgatccat tacaaacttt ctagccatgc
     4501 ctcatctctg acctggatac caagttcttg tgctttttgc agtttacttc cagcgtctgc
     4561 acctaccacg acgaggtcgg tctttttaga aacactacct gtcactttgg cacccagact
     4621 ttcgagttta cttttagctt ctgagcgctt gagtcgttcc aattttcctg tcaataccac
     4681 ggtcaaacct gacaaggccg catccgctac taccgtctgt cctttatagt ccagattgac
     4741 cccagtttct ttcaattctc tgagcagaat ttcagagcct tctgtcgcaa aataagtctg
     4801 aagacttttg gcaatcacgc cacctagact ttcaatacta gccacttcct ctgaatctgc
     4861 ctgatacaga ttttcaattg aatggaaata ttgaagtaaa agctgactag ccttgcttcc
     4921 gacatgacga attcccaaac caaataagag cttctcggca gaattttcct ttgatgcttg
     4981 gatagcctga tacagtttag cagcggactt ttccttaacc ccctctaaaa ggaggaaatc
     5041 ctcttcttgc aaacgataaa tatccgccac atccttgact aaattagcag caaaaagctt
     5101 ctcaacaata gatggaccaa ggcctgtaat attcatagca tcacgagaag caaagtgaat
     5161 caagccttcc atgatttgag cagggcaacg cggattgata caacgtaggg ccacttcatc
     5221 ttcaaagtgc aacaagtcag agttacaact tggacagttt gtagggatat ctagtttttc
     5281 ttcagaaacc cgtttggact ctaccacacg taaaacggca gggatgatgt caccagcctt
     5341 atatacaatg accgtatcgt cttttcggat atctttttca gcaatataat ctacattgtg
     5401 cagggtcgca cggctaacag tcgtaccggc aagttgtact ggtgttagat tagcagttgg
     5461 agttacaaca ccggtacggc caactgtcca gtcaactgat aagagttgag cttctttttc
     5521 ttcagcaggg aacttgtagg ctactgccca ctttggagcc ttaacggtaa aaccaagttc
     5581 ttcttgactt gctaggtcgt tgaccttgat taccactcca tcaatatcgt aaggcagatt
     5641 tccccgttcc tgtcctactt cttggataaa attccagatt tcatctatgt tttcagccaa
     5701 gattcgctta ggattgacca caaaacctag ttgttctagg tacttcaaac ccttttcttg
     5761 gctatcacga gttgaagggc tggcttcttg atagagaaac gttgcaagat tacgcttggc
     5821 aactactgct gtatccaact gacgcagagt tcctgctgcc gcattacgag gattagcaaa
     5881 ttcaggctct ccattttctt ggcgcacttg gttaacttgg tcaaaggaag cgcgtggcat
     5941 gtaacattcc ccacgaactg tgatatctag ttcttctggc aaagtcaaag ggatgtcctt
     6001 aacacgcttg aggttttctg tgatattttc accaattgaa ccatctccac gtgttacccc
     6061 agcaaccaaa atcccctttt cataagtcag cgagatagat aagccatcga ttttcagctc
     6121 acaaatatag gtcggatgag ccacttcctt acgaacacgc gcatcaaaag catctagctc
     6181 ctcacgtgaa aaagcatcct gcaaactata aagaggatac tgatgactgt atttttcaaa
     6241 accatctaaa accttgccac caacacgatg agtcggactg tctgctagca cttgctctgg
     6301 ataagcagtt tctaactcga ccaactcacg gtaaaggcgg tcatactcac tgtctgaaac
     6361 cgagggatta tcgctggtat agtactcagt cgcatagcga ttgagcaaag cgactaactc
     6421 attcattctt ttattcataa gaccatttta ccataaaaca agccctcctc acaaacgaga
     6481 agggcggaaa aaacacttag tttgaaatta tttttgaaac tcaagcaacc ttatatcaat
     6541 ttttcaaaat gagttcgaac ataaataaac gatatacaag acaagatgat aacaccactt
     6601 ccaattatca ggaaagaaga gagatgtata cttggcaaga ctgtcataaa tccttttgca
     6661 ataggcataa atagaatagc taaggtaaaa attgtactca gtactcttcc aagaaattcg
     6721 ctctcaacct tggtttgtac ttgagtaaaa aagtgaatat taaaaatcgt cataaacaat
     6781 tcacaaacta aatttccaga aaaggaaaga aaagttggaa gtggtaatcc catcataaaa
     6841 actccgacac ctgtcaaagc cagtaaaatc aaaagattat aaatattagc tttaatttta
     6901 ctagctagaa gagccccaat gatgaaacca atagccccca tagttaaaat acttgcatag
     6961 gctccttctg acccgtaaag ctgattcgaa aagggaagta gaaattcaaa agctgcaaaa
     7021 aagaaattaa cgctggaagc taccagcaaa aggaagaaaa tttcttgctg atgccagata
     7081 tagtgtaacc catccttgat atctacaaaa atatctctcc cagtaaaagc ctttttctct
     7141 tgaacttttg cttcctcttt tggaaggaaa gccactagaa caaaagcaat gaaaaaagtc
     7201 agcgagtcta gcagtagcgt catatggaga cttgcaaact gtaaaacaag gaaggaaaga
     7261 acaggagagc taacacctac aacctgcaaa accagctcta agcgagaatt atagatcaca
     7321 atctcatctt tctccaccac ttcagttatg atagctttat tggctgtgcg agaaaaggca
     7381 aaagcaatag cctgcacaat gttagcaaca atcaaagcgc caatcatcca gctatcattc
     7441 cttatgaaag aaatagccag acaaagaatc ccacaaacaa gatctgccgt cattaaaatc
     7501 ttacgacgag aaaaacggtc tgaaataact ccgccaaagg gattgacgag aatagatgtg
     7561 acgagctcag aaatctgata cattcctaaa actgtctgtc ctatagtccc catagaagcc
     7621 aaccagacac tatttccata atcatagagc atatttccca ttttattgat agccccacgg
     7681 ctaatcaact gcactgcata gcgattcata ttaaagctcc tctcaaattt tgaaactatt
     7741 gtatcaaaac cgaaaggagc tttttatttt ttcccttatt tgggaaaatt aacttttgac
     7801 aaatttttcg tagtgttcct gataataggc tacttgctct ggaagaccta acacatcaaa
     7861 aatatgtatg gcctcttgca tctgcttaca gccttcttta cactgtcctt tttgatataa
     7921 ggcaaaacct tttaaataat ggaaaacatt acgctcataa agcttaatac ctttgtcaat
     7981 aatcttctct gtataagcct caaaatagtt ggcattataa aaagaagaat gctctaaaca
     8041 atgctggtaa caattgaggg ccaaaatcaa aactaatctc ttatggcgac taatctcttg
     8101 gtaaaattcc tccctctcca taacttctct accaatccga gtgacatagt ctacatcgta
     8161 gaaactatag aggttaccga aaagaatcaa ctcatacatg gtccattctt ctgttttgaa
     8221 gaaataatct gctaccttat ccaaatcatc ctgcttcata tcataactcg catctctttg
     8281 acaaatcaga ccttgtagca aaatccagtt cagctcaaaa taaaggggag tcgtcgaact
     8341 cttagacttt tcaagttgtt ctctttgaag cttttgaaaa cctgcaatat cgtttgaata
     8401 gtaaagtggg ataatctgtg ccatcataga cacatgttca tgattatgaa aattccttgc
     8461 cttatccatg aaattttcga ttgttacatg aatgttatcc aaaatctcaa agaaacggga
     8521 gactgccagg tcagactccc caagctcaaa gcgagataac tgagaggtag agcaggattc
     8581 gcctgctgct tcctttaaag aataatttcc acttgttcga aattcacgaa atacttttcc
     8641 aagatgttcc atctttacac ctgatctgat aattcttccc actcaagcat agcttcttcc
     8701 tgacgatggc tgattttgtc cagctcagcc tgtaattcca tgagtttgtc ggcatcgttt
     8761 gtttccaaca tttgttcaga aatggcttgg ctttgacttt ctagctcttc aatttcagct
     8821 tctagacttt cgatttgtcg catgagtttg cgaacttctt tttgactttc tttctgggcc
     8881 tgatagtcat tgactggact tgcttccttt gcttgattgc tagttgaagc ttcctcagtc
     8941 tgactcattt ctgctgttgc tctcttctca atatagtagt cgtaatctcc aaggtagaga
     9001 gttgaaccat tctcagacaa ttccaaaaca tgagttgcca cacgattgat aaagtaacga
     9061 tcatgactga caaaaagcaa ggtaccatca aagtcaatca aggcattttc tagcacttcc
     9121 ttactatcaa tatccaagtg gttggtcggc tcatccagaa tcaaaaagtt attgttttcc
     9181 atagacaatt tagctaaaag caaacgagct ttttcgccac cagatagcat gccgactgat
     9241 tttttaacat catctcctga gaaaaggaag gctccaagac ggttgcggat ttcaacttct
     9301 ggtgtcagtt tgaaatcatt ccagagttca tccagcaccg tattacttgg tgtcagcttg
     9361 ctttgggttt ggtcatagta accaacctca acattagcgc caaagcgctt ttctcccttg
     9421 ataaaaggaa tctggtccac aatagacttg ataaaggttg acttgccgat accatttgga
     9481 ccaacgatag cgacagcatt catcttacga agatctacgt taatcggttg tgacaggact
     9541 tccccgtcat aaccaatagc agtattttca acagtcaaaa caacattgcc cgacgttttt
     9601 ttagactgga aggtcatgtt ggctgctttc ttgccagctt caggcttgtc caaacgctcc
     9661 attttttcta gttgtttacg gcgagattga gcacgtttag tcgttgaagc acgaactaga
     9721 ttgcgattga caaagtcttc cagagcagcg atttccttct gttgcttttc atagtttttt
     9781 gcctcagtag ctagcttttg ctccttcaat tcgacaaaac gagagtaatt ccccacatag
     9841 cgatccaagg aatgcttggt caaatctagc gtaattgtcg caaccttgtc caagaaataa
     9901 cggtcgtggc tgacgataat gagggcaccg ctatagttta ccaagtaatt ctctagccag
     9961 gcgatggttt caatatccaa gtggttagtt ggctcgtcca agaccaagag attgggcttt
    10021 tcaaggagca ttttagctag agccaaacga gtattttgac cacctgaaag ttcagctatt
    10081 ttcatctgcc acatagactc gtcaaacttg aatccattca aaatcgctcg aatatcagct
    10141 tcataggtaa agccgcctgc ttggcgaaaa ttctcagata agtggtcgta atctgacatc
    10201 agtttatcca attcatcgcc agacttttca cccatctcca actccatctg acgaagttgt
    10261 ttatctgtcc gacgtaagtc atcaaagaca tgaagcatct catcatagat ggtattttca
    10321 gactcaaaac ggctatcttg agctaggtaa gacagagaaa tatctttttt cttattgatt
    10381 tctccactag ttggctcctc ttctccaact aaaatcttca aaagagtaga cttacctgca
    10441 ccatttttcc caacaagggc aatccgatct cgttcatcaa cctgcaggtt gatattatcg
    10501 aaaagaacct ctcctgcaaa agaacgttca attttattag cttgtaaaat aatcatacaa
    10561 gtagtatagc atgtttccct aagtcattca agataatcgt aagtctttta gtacaacttt
    10621 tataacataa aataaactaa attatgtata ttttatatta gattccttca ctatcttgtt
    10681 ggattttcta accagctaat cttgtttcaa atagttatcg cacaagccta ttatttaatt
    10741 cttttcatta tttacgtacg c
//
LOCUS       DAVKMJ010000057        10576 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000057 DAVKMJ010000000
VERSION     DAVKMJ010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10576
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.057"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            3..478
                     /locus_tag="VW348_001856"
                     /pseudo
     CDS             3..478
                     /locus_tag="VW348_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            516..818
                     /locus_tag="VW348_001857"
     CDS             516..818
                     /locus_tag="VW348_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEU9746715.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSVPVFDNIRLPAKQNMV"
     gene            826..1627
                     /locus_tag="VW348_001858"
                     /pseudo
     CDS             826..1627
                     /locus_tag="VW348_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            1676..2140
                     /locus_tag="VW348_001859"
     CDS             1676..2140
                     /locus_tag="VW348_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEU9746716.1"
                     /translation="MGGHPGFNCPLLDDEVYEDYYLEFEKEETCSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSKDAVTLDELQSRTIALRSLKHDRGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            2297..2722
                     /gene="lacA"
                     /locus_tag="VW348_001860"
     CDS             2297..2722
                     /gene="lacA"
                     /locus_tag="VW348_001860"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEU9746717.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            2753..3268
                     /gene="lacB"
                     /locus_tag="VW348_001861"
     CDS             2753..3268
                     /gene="lacB"
                     /locus_tag="VW348_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEU9746718.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPTEENKKLIAKIEHVESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            3279..4208
                     /locus_tag="VW348_001862"
     CDS             3279..4208
                     /locus_tag="VW348_001862"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEU9746719.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQVLYDQLIVKEV"
     gene            4210..5190
                     /gene="lacD"
                     /locus_tag="VW348_001863"
     CDS             4210..5190
                     /gene="lacD"
                     /locus_tag="VW348_001863"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEU9746720.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGETAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            5424..6260
                     /locus_tag="VW348_001864"
     CDS             5424..6260
                     /locus_tag="VW348_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEU9746721.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENH
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYCQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            6296..6613
                     /locus_tag="VW348_001865"
     CDS             6296..6613
                     /locus_tag="VW348_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEU9746722.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            6615..8309
                     /locus_tag="VW348_001866"
     CDS             6615..8309
                     /locus_tag="VW348_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEU9746723.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTAKADAILEKA
                     GVEAAQNTITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            8518..9924
                     /gene="lacG"
                     /locus_tag="VW348_001867"
     CDS             8518..9924
                     /gene="lacG"
                     /locus_tag="VW348_001867"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEU9746724.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTDYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            10014..10226
                     /locus_tag="VW348_001868"
     CDS             10014..10226
                     /locus_tag="VW348_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEU9746725.1"
                     /translation="MNFEKCSQILCLTSEELKSLGKWYVSTGKEWICHSDDELEEFKN
                     LFLNFINPEEWDTISFDSDFMPFQQS"
BASE COUNT         3419 a         1793 c         2166 g         3198 t
ORIGIN      
        1 ttatggtatt agattatttc tttgacaaaa accttgtgtt ttgcttagaa gcggataatc
       61 aagaataact ctttgatcag gtagcaagct tgttggagga acgagaaatt gtaactccaa
      121 cttatcgtga agctttgatc acgcgtgaaa agtcatttcc aactggttta gatatggaat
      181 ttctaggaaa ggacttgcaa atgtaatgat tcctcacaca gatattgttc ataatctagc
      241 tgagaaagtg gtggttgttc gattagagaa accggtgact ttccataata tgattgcgcc
      301 aggtaaggaa gtagaagtat ccttgctctt ctttatcatc aataattcaa gttcaagtca
      361 aacgaacatt cttgctcagt tgatggactt tttcacagga aatggacatc ttgaagacct
      421 atcaaaaatt tccgaaccag aaaaacttta tgcttatata gatgaagcaa tcgcttaatc
      481 ttgtctatta aaaaataaaa tcggaggaag tctatatgat taaaattctt gctgcctgcg
      541 gtgcaggtgt taactcaagt caccaaatta aaagtgctct agaagaagaa ctttcaaacc
      601 gtggttacga tgttcactgt gatgcagtta tggtgaaaga tgtaaacgaa gaccttatga
      661 aaggttacga tatctttaca ccaatcgctg caacagacct tggttttgaa ccaggtatcc
      721 cagttatcga agctgggcca atcttattcc gtatcccagc aatgagcgtt ccagtatttg
      781 acaatattag acttcctgcg aaacaaaata tggtatagta gttctatgaa tgatgaagca
      841 agtaaacaac taactgatgc acgatttaag cgtcttgttg gtgttcagcg taccactttt
      901 gaagagatgt tagctgtatt aaaaacagct tatcaactta aacacgcaaa aggtggacga
      961 aaacctaaat taagcctaga agaccttctt atggccactc ttcaatagtg cgagaatatc
     1021 gaacttatga acaaattgcg gctgattttg gtattcacga aagcaacttt atccgtcgga
     1081 gccaatgggt tgaagtaact cttgttcaaa gtggtgttac ggtttcaaga actcctctca
     1141 gctctgagga cacggtaatg attgatgcga cggaagtaca aatcaatcgc cctaaaaaag
     1201 aattagcgaa tgattctggt aaaaagaaat gccacgctat gaaggctcaa gcgattgtca
     1261 caagtcaagg gagattgttt ctttggatat cactgtgaac tattgtcatg atatgaagtt
     1321 gttcaaaatg agtcgcagaa atatcggaca agctggtaaa atcttggctg acagtggtta
     1381 tcaagggctc atgaagatat atcctcaagt acaaactcca cgtaaatcca gcaaactcaa
     1441 gccgctaaca gttgaagata aaacctataa ccatgcgcta tctaaggaga gaagcaaggt
     1501 tgagaacatc tttgccaaag taaaaacgtt taaaatgatt tcaacaacct atcgaaatca
     1561 tcgtaaacgc ttcggattac gaatgaattt gattgctggc attatcaatc atgaactagg
     1621 attctagttt tgcaggaagt ctaataaaga aactagcaag gtcaggcctt actttattgg
     1681 tggacatcca ggatttaatt gtcctctact tgatgatgaa gtctatgaag attattatct
     1741 agagtttgag aaagaagaga cttgctctgt tccacgtcct ttcccagaaa caggtatgtt
     1801 ggatttccaa gatagaagtc catggctaga gggacaaaaa gaaatagatc ttagttatga
     1861 tcttttcagc aaagatgcag tgactttgga tgaattgcaa tctcgaacaa ttgcccttcg
     1921 ttctcttaaa catgataggg gattgaaagt gcattttgca gaatttccaa acctcatcat
     1981 ctggtcaact ttgaacaagg gacctttcat tacctttgaa ccatggtctg gcttgtcaac
     2041 attccttgaa gaaggagatc atttagaaga taagaagaat gtttgtctct tagaagccaa
     2101 tcaggttgaa gaattagggt ttgagataga agttttataa aaaagtaaaa aataaataac
     2161 aaaaacaaac acaaactgtt gacttcttca aacaatagta gtatattatg tttgtgagga
     2221 ctaattgact gttttttaaa gacagccaat acactgctgg aatccagcat agaaaaaata
     2281 aaaaggagta tacaatatgt ctattgttat cggtgcagat gctgcaggtt tgagattgaa
     2341 agaagttgtg aaagacttct tagaaaaaga aaacttccac cttgtggatg ttacagctga
     2401 aggtcaagac tttgttgatg tgactctcgc tgttgctgca gaagtaaaca aagaagaaca
     2461 aaaccttggt atcgtgattg atgcttatgg agctggtcca tttatggttg caactaagat
     2521 caaaggaatg gttgctgcag aagtttctga tgaacgttca gcttatatga ctcgtggcca
     2581 caacaactca cgtatgatca ctatgggtgc acaacttgtt ggtgatgaat tggctaaaaa
     2641 catcgctaaa ggatttgtta atggtaaata cgacggtggt cgtcaccaaa tccgggttga
     2701 catgttgaac aaaatgggct aattagatta tagtaagaaa ggtaagttaa aaatgagaat
     2761 tgcaattgga tgtgaccaca tcgtaacaga tgaaaaaatg gcggtttcag aatttttgaa
     2821 atcaaaagga tatgaagtca ttgactttgg tacatatgac catacacgta ctcactaccc
     2881 aatctttggt aaaaaagtag gggaagctgt aactagcggt caagctgatc ttggagtatg
     2941 tatctgtggt actggtgttg gtatcaacaa cgctgtaaat aaagttccag gtgttcgttc
     3001 tgccttggtt cgtgatatga caacagccct ttatgctaaa gaacaattga acgctaacgt
     3061 tattggtttt ggtggtaaaa ttactggtga attgcttatg tgtgatatca tcgaagcttt
     3121 catccatgct gaatacaaac caactgaaga aaacaaaaaa ttgattgcga aaattgaaca
     3181 tgttgaaagt cacaatgctc aacaaacaga cgcaaacttc ttcactgaat tccttgaaaa
     3241 atgggatcgc ggagaatacc acgactaaga ggtaacctat gattttaaca gttacaatga
     3301 acccatccat tgatatttcc tatcccttgg atgagttgaa gattgatact gtcaatcgtg
     3361 tggtggatgt aaccaaaacg gctggtggta agggactcaa tgttacccga gtactttcag
     3421 aatttggcga ttctgttctt gctactggtt tagtgggtgg caaacttggt gagtttttgg
     3481 ttgaacatat cgataatcaa gtaaagaaag atttcttctc aattcaggga gaaactcgta
     3541 actgtatcgc tattctccac ggagacaacc aaacagaagt tcttgaaaaa ggtcctgaag
     3601 tattggaaca ggaaggtcaa gactttttgg aacatttcaa aaaactcttg gagtcagttg
     3661 aagtagtggc catctcaggt agtctgccag ctggccttcc agttgattac tatgcgagct
     3721 tggtagaact tgctaatcaa gctggcaagc ctgtagtctt ggactgctca ggtgcagcac
     3781 ttcaggctgt tcttgaatca ccccataaac caacagtcat caaaccaaat aatgaagaat
     3841 tgtctcagct tcttggaaga gaagtttctg aggatttgga tgaattaaaa gaagtacttc
     3901 aagaaccttt gtttgcaggg attgaatgga ttatcgtttc acttggtgcc aacggtactt
     3961 ttgccaaaca tggtgacact ttctacaagg tagatattcc tagaattcag gtggtaaatc
     4021 ctgttggatc tggagactct actgtggcag gaatttcttc aggacttctt cacaaagaat
     4081 cggatgcaga attactcatc aaggcaaatg tccttggtat gctcaatgct caagaaaaaa
     4141 tgactggtca tgtcaacatg gccaactatc aagttctata tgatcaatta atagtaaaag
     4201 aggtataaaa tggctttaac agaacaaaaa cgtgtacgct tagaaaaact ttctgatgaa
     4261 aatggtatca tctcagctct tgcatttgac caacgtggtg ctttgaaacg cctcatggct
     4321 caacaccaaa cagaagaacc aactgtggcc caaatggaag aacttaaagt cttggtagca
     4381 gatgaattga ctaaatacgc ttcatctatg cttcttgacc ctgagtatgg acttccagca
     4441 actaaagctc ttgatgaaaa agctggtctt ctccttgctt atgaaaaaac aggttatgac
     4501 acaacaagca caaaacgctt gccagactgc ttggatgtct ggtctgcaaa acgtattaaa
     4561 gaagaaggtg cagatgcagt taaattcttg ctttactatg atgtagatag ctcagacgaa
     4621 ctcaatcaag aaaaacaagc ctacatcgaa cgcatcggtt ctgagtgtgt ggctgaagat
     4681 atcccattct tccttgaaat tcttgcttac gatgaaaaaa ttgcggatgc aggttctgta
     4741 gaatacgcga aagtaaaacc acacaaagtt atcggcgcta tgaaagtctt ttcagaccca
     4801 cgctttaaca ttgatgtctt gaaagttgaa gttcctgtta acattaaata tgttgaaggc
     4861 ttcgctgaag gtgaagtagt ttatacacgt gaagaagcag cagccttctt caaagcgcaa
     4921 gatgaagcaa cgaacttgcc atacatctac ttgagtgctg gtgtatcagc taaactcttc
     4981 caagatactc ttgtatttgc tcatgaatca ggtgcaaact ttaacggagt tctttgtggc
     5041 cgtgcaacat gggctggatc agttgaagca tacatcaaag atggtgaaac agcagctcgc
     5101 gaatggcttc gcacaactgg atttgaaaac attgatgagc tcaacaaagt tcttcaaaca
     5161 acagcaactt catggaaaga acgtgtgtaa gaaagtcctc ctagtttagg aacatgaatc
     5221 taaaaaaatt taaaaaaagt tgtatgtaaa ggtttacaaa ataacttact tgtgctatac
     5281 ttaaatcaca agttaataca aggtgagtgt tactaagtaa tattaggcat gatcacaggt
     5341 gaattagaaa tcagctgatt ttctagttca tttgtggtca ttttttgtac tcatatacct
     5401 ttaagatata aaaggaggtt gacatgtatc gaattctaaa tccaatgaat cacaatgtct
     5461 cgcttgtcag aaatgataag ggagaagagg tgattgtaat tggtaagggg attgcattcg
     5521 gaaagaagaa gggggatttg attgctgaaa atcatgttga gaaaatcttt cggatgaaga
     5581 ccgaagagtc cagagaaaac tttatggctc ttctcaaaga tgttccgctt gattttatca
     5641 cagtgaccta tgaaatcatt gataagctat caaagaaata tcattatccg attcaagagt
     5701 atctctatgt aaccttgaca gatcatattt actgttctta tcaagctcta actcaaggaa
     5761 ggtacaagga tagtaatctg ccagatattt ctgctaagta tcctgtcgct tttcaaatcg
     5821 caaatgaagc ttttgaaatt tactgtcaga agctagcaga tcattttcct gaggacgaaa
     5881 ttattcggat tgcttatcat ttcattaatg ctgaaggtga aaatgaagtg gaacttgtgg
     5941 agtcgattga taagaggaaa gaaattctca ggaatgttga agaagtttta acggactatg
     6001 caattcaacg aactaaaaag aataaccatt tctatgatcg ctttatgatc catttgaatt
     6061 atttcttgga ttatttagac agatctagag atgataacca atcacttctg gatatggaag
     6121 atcatattaa acaatcctat ccaaaagcct tcgagattgg ttccaagatc tatgatgtga
     6181 ttacgcaaca tacgggtctt gatttgtata aaagtgaacg agtttatcta gttctacata
     6241 tccaacgttt attgtcataa aaatttattt aaaactatat aaggagaatt ctatcatgaa
     6301 tagagaagaa gtaacattgt taggttttga aatcgtagcc tatgctggcg atgctcgttc
     6361 aaaactattg gaagccttga aggctgctga agctggtgat tttgaaaaag cggacgctct
     6421 ggtagaggaa gctggtagct gtattgcaga ggctcaccac gcgcaaacaa gtctattgac
     6481 taaggaagct tctggtgagg acttagcgta tagtgtgacc atgatgcatg gtcaagatca
     6541 cttgatgaca actatcttgt taaaagacct aatgcaccat ttaattgaac tttacaagag
     6601 aggagttaaa taaaatggat aagttaataa tttttattga gaaaggaaag cctttctttg
     6661 agaaattatc gagaaatata tacttaagag cgataaaaga tggttttatt tccagtatgc
     6721 cagcagtatt attctcaagt atttttatac taatagctgc tgtgcccaat atttttgggt
     6781 ttaaatggtc tgatgaacag ttagctttta ttttgaaacc ttacaactac tcaatgggga
     6841 ttttagctct cttagtagct gggacaactg caaaatcgtt aacagattca gttaatacac
     6901 gtagtatgga gaaaaccaac caaatcaact acatgtcaac ttttttagca gctgttgttg
     6961 gattgttaat actggcagct gatccaattg aaggtggatt tgctaatggt cttttaggta
     7021 ctagaggatt acttactgca tttttggcag cttttattac agtaaatatc tataaagtat
     7081 gtattaaaaa taatgtaacc attagacttc ctgaagaggt tccaccaaat attgcacaag
     7141 tttttaaaga tgttattccg tttgccttat ctgttctttc aatatatgga ttggatttaa
     7201 ttgttagaaa tatttttggt acaaatgtag cagaatctgt tggtaaaata ttagcccctc
     7261 tattttcagc tactgatggt tatatcggtt tagctattgt atttggtgct tatgctttct
     7321 tttggtttgt tggaattcat gggccatctg ttgtagaacc tttaattgta gctatcagtt
     7381 atgcaaatat agaagctaat gttcagcttg tgcaagctgg tatgcacgca gataaaattt
     7441 taaatccagt tactcaaact tttgttgtaa caatgggtgg tactggtgca acactagtag
     7501 ttccatttat gtttatgtgg ttatgtaaat caaaaagaaa tagaattgtc ggacgtgcgt
     7561 ctgtagttcc tactttcttt ggcgtaaatg aaccaatcct atttggtgct ccaattgttt
     7621 taaatcctat cttctttatt ccgtttgtta ctgctcctat tatcaatgtt tggattatga
     7681 aattttttgt agatgttcta caaatgaata gtttcagtat tattttacct tggacaacac
     7741 ctgctccaat tggtattgtt atgggaacgg cgctggctcc attgtcattc gtcttggcta
     7801 taactttaat cattatcgac actttaatct attatccatt tgttaaagtt tatgaccatc
     7861 aaattttaga agaagaacgg aaaggaaact cttcatctga attgaaagaa aaagttgctg
     7921 caaacttcaa cactgcaaaa gcggatgcta ttcttgaaaa agcgggtgta gaagcagcac
     7981 aaaatacaat cactaaagaa acaaatgtcc tcgttctctg tgcaggtgga ggaacaagtg
     8041 gtctccttgc aaatgctttg aataaggcag cagcagaata caatgtccct gtgaaagcag
     8101 cagcaggcgg ctatggtgct caccgtgaaa tgttaccaga gtttgatctt gttatccttg
     8161 cccctcaagt tgcttcaaac tttgaagata tgaaagcaga aacagataag ctcggtatta
     8221 aactagcgaa aacagaaggc gctcaataca tcaaattaac tcgtgatgga aaaggtgctc
     8281 ttgcattcgt acaagcgcaa ttcgattaag gctagagact ctgaaatagt ctcctatcgt
     8341 tacggaaatc gctatggcga atttcctatt attaattcgt cggtaaaaag atatcgtttt
     8401 tacctcctca tgtcacaatt cggtgacttg gtacaagaag tgagatggag aaggatggct
     8461 cattgactcc tctcctctca cttttacttt atttaaatca agaaataggt gaaaaaaatg
     8521 acaaaaacac ttccaaaaga ctttattttt ggtggcgcaa cagctgccta tcaagcagaa
     8581 ggtgctacac atactgatgg taaaggacca gtagcgtggg ataaatatct tgaagataac
     8641 tactggtaca ctgcagaacc agccagtgat ttttacaatc gatatccagt tgacctcaag
     8701 ctagcagaag agtatggtgt caatggtatt cgaatttcta ttgcttggtc acgtattttc
     8761 ccgactgatt acggccaagt aaatgctaaa ggtgttgagt tttatcataa tttatttgca
     8821 gagtgtcaca aacgtcatgt tgagcctttt gtaactcttc atcactttga cacgccagaa
     8881 gctctccact caaatggaga cttcttaaac cgtgaaaata tcgaacattt tgtagactac
     8941 gctgccttct gttttgaaga atttccagaa gtaaactatt ggacaacctt taatgaaatt
     9001 ggaccaatcg gtgatggtca atatttggtt gggaaattcc ctccaggtat ccagtacgac
     9061 cttgccaaag tctttcaatc acaccacaat atgatggtgt ctcatgcacg cgcggtaaaa
     9121 ttgtacaaag agaaaggcta taaaggggaa attggtgttg ttcacgccct gccaactaaa
     9181 tatcctctag atcctgaaaa tccagcagat gttcgtgcag ctgagttgga agatatcatc
     9241 cacaataaat tcatcttaga cgcaacttat ctaggtcgct attcagctga aaccatggaa
     9301 ggtgtcaacc atatcttatc agtcaatggt ggtagcttgg atcttcgtga agaagatttt
     9361 acagcattag aagctgcaaa agacttgaat gatttcctag gaatcaacta ctatatgagt
     9421 gactggatgg aagcctttga tggagaaact gaaattatcc ataatggtaa aggtgaaaaa
     9481 ggaagctcta agtatcaaat caaaggtgtt ggtcgtcgtg tagctcctga ctatgtacca
     9541 cgcacggatt gggattggat tatctaccct caaggtttgt atgaccaaat catgcgtgtg
     9601 aagaaagatt atcctaacta caagaagatt tacatcactg aaaatggtct cggctataaa
     9661 gatgagttcg ttgataacac tgtttacgat gatggtcgta ttgattacgt gaaacaacac
     9721 ttggagatct tgtctgatgc gattgcagat ggagctaatg taaaaggtta cttcatttgg
     9781 tcattaatgg atgtcttctc atggtcaaac ggttatgaga aacgttatgg tctcttctac
     9841 gtagattttg aaactcaaga acgttatcct aagaaatcag ctcactggta caagaaagta
     9901 gcggaaactc agattataga ctagtagaat tagtcattag atatagaatt ttagtgagtc
     9961 aaaaagatgt tcaaagattt tatccaatct atttatgaaa aaaagtttat attataaatt
    10021 tcgaaaaatg ctctcaaata ctgtgtttga cgagtgaaga attgaaaagt cttggaaaat
    10081 ggtatgtctc gactggtaaa gaatggattt gtcattcaga tgatgagctg gaagaattta
    10141 aaaatctatt tttaaatttt atcaatcctg aagaatggga tactatctcc tttgattcag
    10201 attttatgcc gtttcaacaa tcgtaaccaa tttctcaaaa aagttaaatc ttatatttag
    10261 tactctgtaa aactcttatc taatcacgtt gcttatactc aatgaaaatc aaagagcaac
    10321 tttaaactag gaagcgagtc gcagatttct caatgcatag ctttgaggaa ttgggcaaaa
    10381 agtctttgat atagaaaaaa gcatagtatc aggtgttgaa acacctgata ctatgctttt
    10441 tattgtggga agatttactt tttttcttct gaaattgagt tgttacccag gctctttcag
    10501 tttattaagg cttgatgact ttaatgtgtt tagatagctt aaaaaggatt gaatcactta
    10561 gtttagaatc tgaaac
//
LOCUS       DAVKMJ010000058        10361 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000058 DAVKMJ010000000
VERSION     DAVKMJ010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10361
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.058"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            165..3266
                     /locus_tag="VW348_001869"
     CDS             165..3266
                     /locus_tag="VW348_001869"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEU9746726.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     EIEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQKSEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQVDD
                     SKKKLDVTLFSDLYRQVGQEVREGAFYYIKGKVQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHDSDQEMSRILDQYKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNGIVMKT
                     IYR"
     gene            3348..4355
                     /gene="pfkA"
                     /locus_tag="VW348_001870"
     CDS             3348..4355
                     /gene="pfkA"
                     /locus_tag="VW348_001870"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEU9746727.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     L"
     gene            4414..5919
                     /gene="pyk"
                     /locus_tag="VW348_001871"
     CDS             4414..5919
                     /gene="pyk"
                     /locus_tag="VW348_001871"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEU9746728.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(6653..6878)
                     /locus_tag="VW348_001872"
                     /pseudo
     CDS             complement(6653..6878)
                     /locus_tag="VW348_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7726..8598
                     /locus_tag="VW348_001873"
     CDS             7726..8598
                     /locus_tag="VW348_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEU9746729.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            8611..8775
                     /locus_tag="VW348_001874"
     CDS             8611..8775
                     /locus_tag="VW348_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746730.1"
                     /translation="MTVILGFLFLFLMTWWVISIVNSQKPLKNETFIGYVQRYDIDGN
                     GYQSLPCPQN"
     gene            complement(8744..9088)
                     /locus_tag="VW348_001875"
                     /pseudo
     CDS             complement(8744..9088)
                     /locus_tag="VW348_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            9231..9542
                     /locus_tag="VW348_001876"
     CDS             9231..9542
                     /locus_tag="VW348_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746731.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            9546..10262
                     /locus_tag="VW348_001877"
     CDS             9546..10262
                     /locus_tag="VW348_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEU9746732.1"
                     /translation="MKKYFISGLGSNAYHSKDFFQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLALLISKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNGATWREEALKELPDYFNTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
BASE COUNT         3216 a         1785 c         2193 g         3167 t
ORIGIN      
        1 atgctttcta tttttatata caatatagta taaatataaa aatgatgaca aaaatacaaa
       61 tgaatagaaa ataaattagt aagctgatga aatttttctc aagagaagcc atttataggt
      121 gaaaatggta taatatagtg agaaggatag aggagaagtg taaattgatc gcacaactag
      181 atacaaaaac agtctatagt tttatggaaa gcgtcatttc gatcgaaaag tatgtgagag
      241 cagctaaaga atacggctac actcatttgg ctatgatgga tattgacaat ctttatggcg
      301 ctttcgactt tctagagatt acaaaaaaat acggcattca tcctttgcta gggcttgaaa
      361 tgacagtgtt tgtagatgat caggaagtga atttgcgctt tttagctcta tctagtgtgg
      421 gctatcagca gttgatgaag ctttcgacag ccaagatgca gggggagaaa acttggtcag
      481 tcctgtccca gtacctggag gatatcgcgg tcattgtgcc ttattttgat agagttgagt
      541 cgttagaact aggctgtgat tactatatag gggtttatcc agaaacacta gcaagcgaat
      601 ttcatcatcc tatcttacct ctttatcggg tcaacgcttt tgaaagcagg gatagagaag
      661 ttcttcaagt tttaacagcg attaaagaaa atctaccgct cagagaagtt cccttgcgtt
      721 cgagacaaga tgtctttata tcagcaagtt ctttagagaa actattccaa gagtgttttc
      781 cgcaagcttt ggacaattta gaaaagctta tttcaggcat ttcttacgac ttggatacta
      841 gtctgaaact gcctcgtttt aatccagcta gaccagcagt agaggagttg agagagcgtg
      901 ctgaactggg gcttgttcag aaggggttga ctagtaaaga atatcaagat agactagacc
      961 aagaattgtc tgttattcat gatatgggct ttgatgatta tttcttggtt gtttgggatt
     1021 tgttgcgttt tggacgatcg aatggctatt atatgggaat gggaaggggt tctgcagtag
     1081 gcagtttggt ttcttatgcc ttagacatca cggggattga cccagtagag aaaaatctga
     1141 tttttgaacg ctttcttaat cgtgaacgct ataccatgcc tgatattgat attgatatcc
     1201 cagatattta tcgtccagat tttatcagat atgttggtaa taaatatggt agtaaacatg
     1261 cggcacaaat cgttactttt tcaacctttg gagccaagca agctcttcga gatgtcttga
     1321 aacgctttgg tgtgccagag tatgaattat ctgcaattac taagaaaatc agttttcgtg
     1381 acaatcttaa gtcggcctat gagggcaatc tccagtttcg tcagcaaatc aatagtaagt
     1441 tagaatacca aaaagctttt gagattgctt gcaagataga gggctatcca agacaaacct
     1501 ctgtccatgc ggctggtgtt gtaattagtg accaagattt aaccaactat attcctctaa
     1561 agtatggtga tgaaattcca ctgactcagt atgatgctca tggagttgag gctagcggac
     1621 ttttgaagat ggactttctg ggactacgaa atttgacctt tgtccagaag atgcaagagt
     1681 tgcttgctga aatagaaggt attcacctta aaattgaaga aatagatttg gaagacaaag
     1741 aaacgttagc tttatttgcc tctggaaata caaaaggtat ctttcaattt gagcaaccag
     1801 gtgccattcg tctgcttaag cgtgtgcaac cagtctgttt tgaagatgtc gtcgcgacta
     1861 cttctctaaa tcgaccgggt gctagtgact atatcaataa ttttgtggca agaaagcatg
     1921 ggcaggaaga agtgactgtt ctggatccag tactggagga tattttggct ccaacctacg
     1981 gcataatgct ctatcaggag caggttatgc aggttgccca gcgatttgcc ggatttagtc
     2041 ttgggaaagc cgatattttg cgtcgggcta tggggaaaaa ggatgcctct gccatgcatg
     2101 agatgagggc ttcctttatt caaggttcat tagaagctgg tcatactgtg gaaaaagcag
     2161 agcaggtctt tgatgttatg gagaagtttg caggttatgg ttttaacagg tcacacgcct
     2221 atgcctactc agccttggcc ttccagttgg cttattttaa aacacattat ccagccattt
     2281 tttatcaggt catgttaaat tcttccaaca gtgattactt aatagatgca cttgaagcag
     2341 gttttgaagt agcctctcta tccatcaaca ccattcccta tcacgataaa attgccaaca
     2401 aggccatcta tctaggtttg aaatccatta aaggagtcag taatgattta gctctctgga
     2461 ttattgaaaa tagaccttat tctaacattg aagattttat agctaaatta cctgagaatt
     2521 atctgaaact tcctctgcta gaacctttgg taaaagttgg tcttttcgat tcatttgaaa
     2581 aaaatcgtca aaaagtattt aataatttag ctaatctatt tgaatttgtg aaagagttgg
     2641 gaagtttgtt tggagatgct atttatagtt ggcagaaatc ggaagattgg acggaacaag
     2701 aaaaatttta tatggaacaa gagcttttag ggataggtgt cagcaaacat ccactacaag
     2761 ctattgcaag taaggctatt tacccgatta ccccaatcgg aaatttgtca gaaaatagct
     2821 atgctattat tttggttgaa gttcagaaaa taaaagtgat tcgtaccaaa aagggtgaaa
     2881 atatggcttt cttacaggtg gatgacagta agaaaaaatt ggatgttaca ctcttctcag
     2941 atttatatcg acaggttggt caggaagtaa gagaaggagc attctactat atcaaaggga
     3001 aagtccaatc acgtgacggt cgtctgcaaa tgattgcaca agaaataaga gaagcagttg
     3061 ctgaacgctt ttggattcag gttaaaaatc atgactcgga tcaagagatg tcacgtattt
     3121 tagaccagta taaaggccca atcccagtca tcatccggta tgaagaggaa cagaaaacca
     3181 tcgtttctcc ccatcatttt gtagctaaat ctgatgaatt agaggcgaaa ttgaatggaa
     3241 tagttatgaa aacgatttat cgctaaaatt acggaaaata gaagaatttt caacgtaaat
     3301 gtggtataat cagtaagaat gttaaaagaa aaaggagcat aaccaatatg aaacgtattg
     3361 ctgttttgac tagtggtgga gacgcccctg gtatgaacgc tgccatccgt gcagttgttc
     3421 gtcaagcaat ttcagaagga atggaagtgt ttggtatcta tgacggatat gctggtatgg
     3481 ttgccggtga aattcatccc ctagatgcag cttcagtagg ggacatcatt tctcgtggtg
     3541 gtactttcct tcactcagct cgttacccag agttcgctca acttgaaggg caacttaaag
     3601 ggattgagca attgaaaaaa cacggaattg aaggtgtagt tgttatcggt ggtgacggat
     3661 cttaccacgg cgctatgcgt ttgactgaac atggcttccc agctattggt cttccaggta
     3721 caatcgataa cgatatcgtt ggtactgact ttacaatcgg ttttgacaca gcggttacta
     3781 ctgccatgga cgctatcgat aagattcgtg atacatcatc aagtcaccgt cgtacttttg
     3841 taatcgaagt tatgggacgt aacgctggtg atatcgctct ttgggctggt attgcaactg
     3901 gtgctgatga aatcatcatc cctgaagcag gcttcaagat ggaagatatc gtagcaagca
     3961 tcaaagctgg ttatgaatgt ggtaaaaaac acaatatcat cgtcttagct gaaggtgtga
     4021 tgtcagcggc tgaatttggt caaaaactta aagaagctgg agatacaagc gaccttcgtg
     4081 taacagaact tggacatatt caacgtggtg gttctccaac tgcgcgtgac cgtgttttgg
     4141 cgtcacgtat gggtgcacat gctgttaaac ttcttaaaga aggtatcggt ggtgttgcgg
     4201 ttggtattcg taacgaaaaa atggttgaaa atccaattct tggtactgca gaagaagggg
     4261 cattgtttag ccttactgca gaaggtaaga ttgtggttaa caacccacac aaagccgata
     4321 ttgagctatc tagcttgaat aagagcttgt tataatttac aatttagtta ataagaccaa
     4381 aaaggtcata tatataaagg agtcacaaaa atcatgaaca aacgtgtaaa aatcgttgca
     4441 actttgggtc ctgcggtaga aatccgtggt ggtaaaaaat tcggtgagga cggatactgg
     4501 ggtgaaaaac ttgatgttga agcttcagct aaaaacattg ctaaattgat tgaagctggt
     4561 gctaacacat tccgattcaa cttctcacac ggcgaccacc aagaacaagg tgagcgtatg
     4621 gcaactgtta aacttgcgga aaaaattgca ggtaaaaaag ttggtttcct tcttgataca
     4681 aaaggacctg aaatccgtac agaattgttc gaaggtgaag ctaaagaata ttcatacaaa
     4741 actggtgaaa aaattcgtgt tgcaactaaa caaggaatca aatcaactcg tgaagtgatt
     4801 gcgttgaacg ttgctggtgc tcttgatatc tatgatgatg ttgaagttgg tcgtcaagtt
     4861 ttggttgacg atggtaaact tggtcttcgt gtggttgcta aagatgatgc aactcgtgaa
     4921 tttgaagttg aagttgaaaa cgatggtatc atcgctaaac aaaaaggtgt gaacatccct
     4981 aacactaaaa ttcctttccc agctcttgct gaacgcgata acgacgatat ccgtttcggt
     5041 cttgaacaag gtatcaactt catcgcaatt tcattcgtac gtactgcaaa agatgtgaac
     5101 gaagttcgtg caatctgtga agaaactgga aacggacatg ttcaattgtt cgctaaaatc
     5161 gaaaaccaac aaggtatcga taacttagac gaaatcatcg aagcagctga tggtattatg
     5221 attgctcgtg gtgatatggg tatcgaagta ccgttcgaaa tggttccagt ttatcaaaaa
     5281 atgattatca agaaagtcaa tgctgcaggt aaagttgtta tcactgcaac aaacatgctt
     5341 gaaacaatga ctgaaaaacc acgtgcaact cgttcagaag tatcagacgt attcaacgct
     5401 gttatcgacg gaactgacgc tacaatgctg tcaggcgagt ctgcaaacgg taaataccca
     5461 ctcgagtcag taactacaat ggctacaatc gacaagaacg ctcaagctct tcttaatgaa
     5521 tacggacgtc ttgattcaga ttcatttgag cgtaactcta agacagaagt aatggcttct
     5581 gctgttaaag atgctactag ctcaatggat atcaaattgg ttgtaactct tactaagaca
     5641 ggtcatactg cacgtttgat ttctaaatac cgtccaaatg ctgacatctt agcattgaca
     5701 tttgacgaat tgacagaacg tggcttgatg ttgaactggg gtgttatccc aatgttgaca
     5761 gatgctccat cttcaactga cgatatgttc gaaatcgctg aacgtaaagc ggtagaagca
     5821 ggtctcgttg agtcaggcga tgatatcgtt atcgttgctg gtgtgccagt aggagaagct
     5881 gttcgcacaa acacaatgcg tatccgcaca gtacgttaag aaaaatataa aaacctatca
     5941 tatccagctt tctagcctgt atgatgggct ctttttttgt ccagggggca aaaagggggc
     6001 aaaactttca taatggattg atactcttcg aaaatctctt caaaccacgt cagcgtcgcc
     6061 ttaccgtata tatgttactg acttcgtcag ttctatctac aacctcaaag cagtgctttg
     6121 agcaacctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat gaaataagat
     6181 atgcacaaat tgattaggaa attcaaatga atttctacaa atgttttagc aatcgcaatc
     6241 tacttgtcta gattcgatct gatatatttt cgatttaatg atatggtatt taaaacctcc
     6301 aaagtagctt gctccattct tttacttacg tgagtgtaga tgttatttac tgttttagcg
     6361 tttttgtgtt ctactctaac cattatagca ttcttctcag ctagtgtact aaggagtgtg
     6421 tgcctgaaaa tatgggaact aagggctggt ttatcggttt ctctagttta gtatttgcct
     6481 tttgcaaagt gatcttaaat gcctttctct aaatttacat atcactattg tttaacaaaa
     6541 tctaatctac tttaggtcac ttattctttt tttgaaatgt agaatgaact ttttcaaagt
     6601 ttttcgaatc ttttaaaatc tgtttgtttt atatcgccat tctccccctt ttttaattct
     6661 ccctatatag cctgacaact ttcccgatgg tacgaatatg gttgctttcg tctaggtgga
     6721 tgtcggagta ttcgggattg agtttttttg aggtagcctt ggcggagttt cttgacatag
     6781 ttagtgccgt ctacttggaa gatgccgatg gtattatagt caatctgtgg ggtattcttg
     6841 ataaataggt agtcgctgtt tcttatcttt ggctccatgg acttgctgac gacataagcg
     6901 attgggtcgt agtcgtctgg gataatggaa actccataac taaatcgtcg tcctgcatca
     6961 agcggctacc tgcagagata aactacctaa cacgagagta agtagtctgt ctgtagtcgt
     7021 ccagtctgat gatttttacg atacttcgtt tttctgatca tacagttgcc tctcggcata
     7081 ggtcagaact ttaccttgtc tgggtggtgc ccgttggtcg tagatagatt ggatatcgct
     7141 aggagaatcc ttttgaactg gaggaaagag ggcatcaatc aagctactga atactttaac
     7201 taagtcaaat atagtatttt tcttagtaga cctaaccctt ttttcataat ttctaatggt
     7261 gtttttactt atacctatct tagtacccaa ttcttattga gtccaaccat tactagtcta
     7321 tattgtttta tagttgattg agtttggaat agtacgctgt agctgctaaa acatttctag
     7381 gaattaattt gcctttccta atagagttgt tcatatctta tttcaatcta ctatattttt
     7441 cacctctaac aatcgcaatc tcttctttat ccatgaacga aaacgctttc tatctttgta
     7501 agtaaagcat cacacgaaat ccacgaaaat gaaaaccttt gttgtgtttt cgtaaaaaat
     7561 ttgttgacag agcacgaaac gcctactata attaaatcaa gtttaaggaa ataacaaaaa
     7621 aacaaatcgg agggaaagac gatgaacaca ttaaatgaga aagtaatcaa tatctgtaaa
     7681 gcagtagtta aagaaacttt aatccaagac atttaggaga aagaaatgaa gaaatcaaga
     7741 aaattagcca cattaggaat ctgttcagcc ttgtttttag gcttggctgc ttgtcaacaa
     7801 caacatgcta cttctgaggg gacgaatcaa aggcaaagca gttcagcgaa agttccatgg
     7861 aaagcttcat acaccaacct aaacaaccag gtaagtacag aagaggtcaa atctctctta
     7921 tcagctcact tggatccaaa tagtgttgat gcatttttta atctcgttaa tgactataat
     7981 accattgtcg gctcaactgg cttatcagga gatttcactt cctttactca caccgaatac
     8041 gatgttgaga aaatcagtca tctctggaat caaaagaagg gcgatttcgt tgggaccaac
     8101 tgccgtatca atagttattg tcttttgaaa aattcagtca ccattccaaa gcttgaaaag
     8161 aatgaccagt tgcttttcct agataatgat gcgattgata aaggaaaggt ctttgattca
     8221 caagataagg aagagtttga tattctattt tcgagagttc caactgaggc aactacagat
     8281 gtcaaggttc acgctgaaaa gatggaaaca ttcttctcac aatttcaatt caatgaaaaa
     8341 gctcgaatgc tgtctgtagt cttgcacgac aatctggatg gcgagtatct gtttgtaggt
     8401 cacgttgggg tcttagtacc tgctgatgac ggtttcttat ttgtagagaa attgactttc
     8461 gaagaaccct accaagcgat taaatttgct agtaaggaag attgctacaa gtatttgggc
     8521 accaagtatg cggattatac aggcgaggga ctggctaagc cttttatcat ggataatgat
     8581 aagtgggtta aactttaata gtgttatgat atgacagtaa tcttaggatt tttatttcta
     8641 tttttgatga cttggtgggt tatttcaatc gttaatagcc agaaaccact caaaaatgaa
     8701 acatttattg gctatgtcca aagatacgat attgatggga atggctatca atcattaccg
     8761 tgtcctcaga actgagagga gttcttgaaa tcgtaacacc actttgaaca agagttactt
     8821 caacccattg gctccgccgg agtaagttgc tttcgtgaac accaaaatca gccgcaattt
     8881 cttcataagt gcggtattct cacacatatt gaagagtggc cataagaagg tcttctaggc
     8941 ttaatttagg ttttcgtcca ccttttgcgt gtttaagttg ataagctgtt tttaatacag
     9001 ctaacatctc ttcaaaagtg gtacgctgaa caccaacaag acgcttaaat cgtgcatcag
     9061 ttagttgttt acttgcttca tcattcatag aactactata ccatattttg tttcgcagga
     9121 agtctaatgc taaaatctta tcagtgagaa gatttcttaa agtttattct ttgtagtttc
     9181 atctgtatta gtacataatt taacttagag aaaataggag gactaatcga atggaattaa
     9241 aagattttac agaaaaagaa caggaaatga ttaagaaaag gcttacaatg tctaatatta
     9301 gtgacaaaga aactactgag aagattctgg cgctagtacc acaagacttg attaagcgaa
     9361 tcccgttttt tgtcagaaaa catgctacaa cacgtacgat taaacgcatt tcaattgaat
     9421 accctgaact ctacgctgta gctcaaacaa gtggtgagat tccagaaaaa gaacgcgaag
     9481 aattgcgtca gattatcaca actatctttg aacaaaagat gaataagcat agtattaagt
     9541 agagaatgaa aaaatatttt attagcggtt tgggaagcaa tgcctatcat agcaaggatt
     9601 tttttcaaga actagattcg caggtctatt ttctaaatcc atatgaaaag catcttcgag
     9661 atgaaacaga attgaaatca tggtttaaaa atgagattgt agaggaagaa tctatctgtc
     9721 tgataggcca ttctcttgga ggagatttag ctcgttattt cgcatcggaa tttgaagaag
     9781 taaagaaact gattcttttg gatggtggct atctagattt agataagatt ttacctttgg
     9841 atacagagtt agaggaaact aaaaattata tcaaatctca aattgtttcg gacttagctc
     9901 ttcttatttc taaagagaag tccgaagcaa agcattggtc agaaaatatg gagaaagctg
     9961 taagacagtc ctatcactgg aatgttgagt ataatagata tgagttggct ataaattatg
    10021 aaaatataga agcgatactc cgcctacgga gaaaaataca agcttttaag agagaagtgg
    10081 gagatacctt gtttattagt cctcgctatc ctaatggagc tacatggaga gaggaagccc
    10141 taaaagaatt gccagactat tttaatacta tttttttaga aaactttggc catgagcttt
    10201 atactcaagc acctaaagaa atcgctagtc taatgaatga gtggctcgct tattttctat
    10261 gagctacttg tattgctgga aatggtataa gatgaaaatc tacaggctct ataatatttg
    10321 tagtgggtaa atccactata gatattatgg agcctatttt t
//
LOCUS       DAVKMJ010000059         9944 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000059 DAVKMJ010000000
VERSION     DAVKMJ010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9944
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.059"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(71..307)
                     /locus_tag="VW348_001878"
     CDS             complement(71..307)
                     /locus_tag="VW348_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEU9746733.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(375..1295)
                     /locus_tag="VW348_001879"
     CDS             complement(375..1295)
                     /locus_tag="VW348_001879"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEU9746734.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            1493..1897
                     /locus_tag="VW348_001880"
     CDS             1493..1897
                     /locus_tag="VW348_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746735.1"
                     /translation="MKILKRYILELCFILSFALPFIKGANADNGRCFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            2113..2694
                     /locus_tag="VW348_001881"
     CDS             2113..2694
                     /locus_tag="VW348_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEU9746736.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETSGDLTIVIQKKQ
                     GAPSAKSKMEGVFGNCEILKKDKGYYILRSVKE"
     gene            2691..3968
                     /locus_tag="VW348_001882"
     CDS             2691..3968
                     /locus_tag="VW348_001882"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEU9746737.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILVPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            3986..4648
                     /gene="deoC"
                     /locus_tag="VW348_001883"
     CDS             3986..4648
                     /gene="deoC"
                     /locus_tag="VW348_001883"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEU9746738.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            4635..5024
                     /locus_tag="VW348_001884"
     CDS             4635..5024
                     /locus_tag="VW348_001884"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEU9746739.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            5114..6166
                     /locus_tag="VW348_001885"
     CDS             5114..6166
                     /locus_tag="VW348_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEU9746740.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVKDAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            6310..7845
                     /locus_tag="VW348_001886"
     CDS             6310..7845
                     /locus_tag="VW348_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9746741.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            7838..8896
                     /locus_tag="VW348_001887"
     CDS             7838..8896
                     /locus_tag="VW348_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9746742.1"
                     /translation="MFKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            8899..9855
                     /locus_tag="VW348_001888"
     CDS             8899..9855
                     /locus_tag="VW348_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEU9746743.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         2825 a         1757 c         2295 g         3067 t
ORIGIN      
        1 gataattgcg attttcattt tctacctttt cctatttgga gacaaaaaaa cagcctctat
       61 ggactgtttc ttatttagca agtttagctg aaagacgagc tttatcgcgg cttgctttgt
      121 ttttgtgaat caaaccttta gtttctgctt tatcgatagc tgagctagca gcacggaaaa
      181 gttcttcaga tgggtttgct tcgaaagctt ttatagcagt acgcatagct gatttttgag
      241 ctgagttctt ttcgttttgt ttaacgttca attcagcgcg tttgatagct gatttaatgt
      301 ttgccaatgt tcttacctcc atatttacta actataccat tatatatgaa aacttacgtt
      361 ttgacaaggg aaaattattt ttttaagtaa atttcatcga tttcatggtt cttgctttta
      421 tgaagaatca cttctgcacg atttctggtt ggttcaatat aattttgtag atttgtgaga
      481 ttgatactgg tccagacctg atgggcaaag gcttccactt ccccaatcgg catctgagta
      541 aaacgataat agtagctatc agggtcgttt tgggctagac tcagcatttt caagaaacgg
      601 tccagatacc aactttcaat atcatccact ccagcatcta catagatgga aaagtcaaag
      661 aagtcagtga tatagagacg atcgttttgt ggattttgaa agacattgat tccctcaaca
      721 attacaaaat cagcagcttt gacactttgt ttctcttcgg gtacgatgtc gtaaacttca
      781 tgagaataga caggaatatc tacatcttgt ccatttttga tgcggtccaa gaagttgaga
      841 agagcttcca tatcatagct ttcaggaaat cctttacgat ttaaaatccc ctgctcaatc
      901 aaggtttgat tgggatagag aaaaccatca gttgtaacca actcaaccgt agcatctgta
      961 aacgtacggg acagtaggat ttgaagtagg cgactggttg tggattttcc aacggcaaca
     1021 ctcccagaaa ccccaataat aaaaggttga gatttacttt cacgttggag gaaaattcct
     1081 tttgaaaagg ctaaatcttc cttagttcgc ttgtaaatct gaatcagatg agccaagggg
     1141 agatagatat ctgtaacgtc ttggagactg atttggtcat taaaactctt gatagattcc
     1201 aattcttctt ctgtcaaagg aggtgttgtc tttcgatgta aagattgcca agtctggcgg
     1261 ctgatttttt caaaatgtaa aaattcgttg gtcatttgtt ttcccctaga tattttgtct
     1321 atcataccat aaaaatctaa aaaaataaag cggtttcttg aatgtggtaa gtcaatggta
     1381 tatagtataa gtgatcaatt tattgatgaa ataggagata gattctactg atttataagt
     1441 ttataagctt ataaaggggg ctttttagtt cacaacttat aggaggtgta ctatgaaaat
     1501 cttaaaacgt tacatattgg aactctgttt tattttaagt tttgctttac cttttataaa
     1561 aggagccaat gcagataatg gtagatgctt tgtggaaacc tattacggtt ttactttttt
     1621 gatggaacat gctattgtaa cagctgtctt tatctattcg tttttaattg ctttcttact
     1681 aaaaaaacga tgggcgaaat ggattgctgc tggtagttat tgctttttag tcctatggat
     1741 tgcgacagag ggttatttct tccgcatgtc actagaagat ttgatacgac tttggacaag
     1801 tttggaaatc ctgacacaaa cgtatcagtt gggcttttat ctaaacattt tgttgggaat
     1861 tttgttgata ataaagtatt ttaaggttaa gcaatagaaa taataatctg cctgattata
     1921 gatgataaac tttttgtttt tatctggact gtgatattta tagttctaaa tggtttatta
     1981 tttataagtg ttgaaagaga ttgaagaaaa tggcttcgtg actcgctttc ttcggtcttt
     2041 ttcgttttat tatcaatttg taaacgattt acaatttgag tcaaattatg gtaaaatagt
     2101 gtcatgagta aaatgtatta tgcagaaaat cctgacgctg ctcacgacat tcatgagttg
     2161 agagtagagt tgttgggaca aaaaatgacc tttttaacgg atgcgggtgt ttttagcaag
     2221 aaaatagttg actttggaag tcaactattg ctcaagtgtc ttgaggtcaa ccaaggagaa
     2281 actgtccttg atgtaggctg tggttacgga cctttgggtt tgtccttagc taaggcttat
     2341 ggagttcagg ctactatggt tgatatcaac actcgtgcct tagatttagc tcggagaaat
     2401 gctgaaaaaa ataatgcaaa agcgacgatt ttccagtcca acatctatga acaagttgaa
     2461 ggacattttg atcatgtcat ttccaatcct cctatccgtg cgggcaagca agtcgttcat
     2521 gaaatcattg agaaaagtaa agatttcttg gaaactagtg gggatttgac aatcgtcatc
     2581 cagaaaaaac aaggggctcc aagtgctaag tccaagatgg agggtgtgtt tggtaattgt
     2641 gaaatcctta aaaaagacaa gggatactat atccttagaa gtgtgaaaga atgagagcag
     2701 ttgatttaat acaaaaaaaa cgagacggtc aagaactgac ttcaagtgaa attgaatggc
     2761 tggtagaagg ctatgtgtca ggaactgttc ctgattatca gatgtctgcc tttgctatgg
     2821 ctgtttattt taaaggaatg acgactcgag aaatctctga tttaacgatg aatatggtta
     2881 agactgggca agagtttgac ctgtcagcca ttgatggtgt gaaagttgac aagcattcta
     2941 ctggtggtgt cggcgataag gtaaccttga ttttagttcc tcttgttgct agcttcggtg
     3001 tgcctgtagc aaaaatgagt ggtcgtggtc ttggccatac aggcggaaca attgataaat
     3061 tggagtccat taagggctat caagtagaac gtagtcaaga ggattttatt cgtcaggttc
     3121 aggatattgg agtatctgtc attgggcaat cagaccagct ggtcaaagca gataagcttc
     3181 tctatgccct tcgtgatgtg accgcaactg tcgacacgat tcctttgatt gcgagttcgg
     3241 tgatgagcaa gaaaattgcg gcaggggcgg atgctatttt gctagacgtg actgtcggtg
     3301 agggtgcctt catgaagacg gttgatgagg cgcgtgagtt ggctcaaact atggtagatc
     3361 ttggtaaggt tgttggacgg aagacagtag cagtgattac ggatatgagc cagcctttgg
     3421 gacgagcgat tggaaatcgt ctggaaatcc ttgaagcatt ggagattttg caaggtcaag
     3481 gacgtcagga tattacccac tttatttgtg aattggctca aattatgctt ggtttggcaa
     3541 atgttaacaa aactgttgaa gaagttcgcc aacatcttga gaatggtcaa gcactggcta
     3601 agtttgagga aatggtgcaa gcccaaggtg gagacttgga agacctctat cgtcctgtaa
     3661 atgtagctca tgtggtggaa atccctgctc aggaaacggg tgtcatttca gctcttccag
     3721 ctatggactt tggtctttat gccatgaggc tgggtgctgg tcgtgcagtt aagtctgatg
     3781 ccttggacta tgaaacagga attgtttttg aaaagaagat tggagactcc gttcaaaagg
     3841 gtgaaattgt tgcaaaagta tacacaaatg aaaaaattcc acctcaacta gttacagatt
     3901 tccaaaaatg tgttaaaata agtgatgaag tgaaaaaaat ccgtgaaatt gtagaaatca
     3961 tctcctaaat ggagggaaaa ccgaaatgaa attaaataaa tatatagatc atacgctttt
     4021 aaaacaagat gcaaagaaaa aacaaattga tagtttgttg tctgaggcta gagagtatga
     4081 ctttgccagt gtttgcgtta atccgacctg ggttgaacat gctaaaaaag gacttgaagg
     4141 cacagatgtt aaggtttgca cagtagtagg tttccctttg ggagcaacaa cttcagccgt
     4201 gaaagcattt gagacaaaag aagctatcca aaatggtgca gatgagattg atatggtgat
     4261 caatgttgga gctctcaaat caggtaattt agccttggtt gagtcagata ttcgcgcagt
     4321 agtggaagca agtggtgata agttagtgaa agtcattatt gaagcttgcc ttctgacaga
     4381 ccaagaaaaa attgttgttt gccaattggc ccaaaaagct ggggctgact ttgttaaaac
     4441 atctactggt ttttcaactg gtggtgctac gatagcagat gttacattaa tgcgtgaaac
     4501 agttggatct gatatgggag tcaaggctgc tggtggagct cgttcttatg cagatgctct
     4561 tgcctttgtc gaagcaggtg cgacccgtat cggaacgtca gctggggtag ctattttaaa
     4621 aggagaattg gcagatggcg actactgagt tgattgaact ggcaattgaa accagcaaac
     4681 atgcatatgt cccctattct cactttccta tcggagcagt tttagtagcc aaagacggaa
     4741 gtgtttacac gggagtgaat atcgaaaatg ctagctatcc tttgaccaat tgcggtgaga
     4801 gaacagctat ttttaaggct atatctgaag gccaaagaga attttcagaa ttgattgtct
     4861 atggtcaaac tgaaaaaccg atctcgccat gtggtgcttg tcgccaagtg atggctgaat
     4921 tttttgaaca agatctaaaa gtgaccttag tcgcaaaaga taaatcgacg gtcgagatga
     4981 cggtcgggga attacttcca tactctttta cagacttaaa ctagtctgag tcgctctctg
     5041 agtggcacgg tccttgtggc caaccaatcc atacttgcaa catcgttgca catcttattt
     5101 aggaggttca gtaatgaaca agaaacaatg gctaggtctt ggcctagttg cagtggcagc
     5161 agttggactt gctgcatgtg gtaaccgctc ttctcgtaac gcagcttcat cttctgatgt
     5221 gaagacaaaa gcagcaatcg tcactgatac tggtggtgtt gatgacaaat cattcaacca
     5281 atcagcttgg gaaggtttgc aggcttgggg taaagaacac aatctttcaa aagataacgg
     5341 tttcacttac ttccaatcaa caagtgaagc tgactacgct aacaacttgc aacaagcggc
     5401 tggaagttac aacctaatct tcggtgttgg ttttgccctt cataatgcag ttaaagatgc
     5461 agcaaaagaa cacactgact tgaactatgt cttgattgat gatgtgatta aagaccaaaa
     5521 gaatgttgcg agcgtaactt tcgctgataa tgagtcaggt taccttgcag gtgtggctgc
     5581 agcaaaaaca actaagacaa aacaagttgg ttttgtaggt ggtatcgaat ctgaagttat
     5641 ctctcgtttt gaagcaggat tcaaggctgg tgttgcgtca gtagacccat ctatcaaagt
     5701 ccaagttgac tacgctggtt catttggtga tgcggctaaa ggtaaaacaa ttgcagccgc
     5761 acaatacgca gccggtgcag atattgttta ccaagtagct ggtggtacag gtgcaggtgt
     5821 ctttgcagag gcaaaatctc tcaacgaaag ccgtcctgaa aatgaaaaag tttgggttat
     5881 cggtgttgat cgtgaccaag aagcagaagg taaatacact tctaaagatg gcaaagaatc
     5941 aaactttgtt cttgtatcta ctttgaaaca agttggtaca actgtaaaag atatttctaa
     6001 caaggcagaa aaaggagaat tccctggcgg tcaagtgatc gtttactcat tgaaggataa
     6061 aggggttgac ttggcagtaa caaacctttc agaagaaggt aaaaaagctg tcgaagatgc
     6121 aaaagctaaa atccttgatg gaagcgtaaa agttcctgaa aaataatgga tggaagtcat
     6181 ttcttaggaa gcggccaagg gccgcttttt taagagttga gacaaagtca ttttgtctca
     6241 gtaaagcttg ctactagaca aactagcaag ttttattgaa ataaaataag actctgaaag
     6301 gaagagcaca tggcacacga aaatgtcatt gagatgcgtg atattaccaa ggtgtttggt
     6361 ggatttgttg ccaacgacaa aatcaacttg cacctacgaa aaggtgaaat tcatgcactt
     6421 ttaggagaaa atggggctgg taagtccacg ctaatgaaca tgttagcagg ccttcttgaa
     6481 ccaactagtg gtgaaatcgc ggtcaacggt caagttgtca atctcgactc cccatctaaa
     6541 gcagctagct tgggaatcgg gatggttcac cagcacttta tgttggttga agccttcaca
     6601 gtggctgaaa acatcatttt aggtagtgaa ttgactaaaa atggtgtgct agatatcgct
     6661 ggagctagca aagaaatcaa ggctctttct gaacgttatg gcttagctgt tgacccttct
     6721 gccaaggtag cagatatctc agttggagcc caacaacgtg tagaaatttt aaaaacactt
     6781 tatcgggggg ctgatatcct tatctttgac gaaccaacgg ctgttttgac tccatcagaa
     6841 attgatgagt tgatggctat tatgaaaaat cttgtcaaag aaggaaaatc aattatcttg
     6901 attacccaca aattggatga aattcgcgca gtttctgacc gtgttacagt tatccgtcgt
     6961 gggaaatcaa ttgaaaccgt tgaaattgca ggggctacca atgctgattt ggcggaaatg
     7021 atggtaggac gttctgtttc ctttaaaaca gagaagcaag cctctaaacc aaaagaagtg
     7081 gttttgtcta tcaaagattt ggtggtcaat gaaaaccgtg gtgttccagc tgttaaaaat
     7141 ctgtccttgg atgttcgtgc tggagagatt gttggtattg cggggattga tggaaatggt
     7201 cagtctgaac tgattcaagc cattacaggt cttcgtaagg ttgaatctgg tagcattgag
     7261 ctaaaagggg attcaattgt aggcttgcac ccacgtcaga ttacagaact aagtgttggg
     7321 cacgttccag aagaccgtca ccgtgatggc ttgattttgg aaatgatgat atctgaaaat
     7381 attgcccttc aaacctacta taaagaacca catagtaaaa atggaatttt gaattattca
     7441 aatattactt cttatgctaa aaagctgatg gaagagtttg atgttcgcgc tgccagtgaa
     7501 ttagttcctg cagctgcact ctcaggagga aatcaacaaa aagcaattat tgctcgtgaa
     7561 attgatcgag atcctgatct ccttatcgtt agccagccaa ctcgtgggtt ggatgtcggt
     7621 gccattgagt atatccacaa acgcttgatt gaagagcgtg ataatggcaa ggctgtcctt
     7681 gttgtcagct ttgaattgga tgagatttta aacgtctcag accgtattgc cgttatccac
     7741 gatggtaaga ttcaaggtat tgtatcacca gaaacaacca ataaacaaga acttggtgtc
     7801 ttgatggctg gtggaaactt gggaaaggag aagagtgatg tttaaaaaat tacaacaaat
     7861 ttcggttccc ttgatttctg tatttctagg aattttactc ggagccattg tcatgtggat
     7921 cttcggttat gatgctattt ggggctacga agaattgttc tatacagcct ttggcagtct
     7981 gcgtgggatt ggagaaatct tccgtgctat gggtcctctg gtcttgattg gtcttggttt
     8041 tgcggttgcc agtcgagctg gtttctttaa cgtcggactt cctggtcagg ctttggcagg
     8101 ttggattctc agtggttggt ttgccctgtc gcatccagat atgccccgtc ccttgatgat
     8161 tctagcaacc atcgtgattg ccttgattgc tggtgggatt gtcggagcga ttccaggtat
     8221 tcttagggcc tatctaggga cgtcagaggt tattgtaacc atcatgatga actacattgt
     8281 cttgtatgta gggaatgcct ttatccatgc tttccctaaa gacttcatgc aaagtacaga
     8341 ttcgaccatt cgtgttgggg ctaatgcaac ctatcagaca ccttggttgg ctgagttgac
     8401 tggtaactca cggatgaata ttggtatttt ctttgccatc attgccgttg cagttatttg
     8461 gttcatgctc aagaaaacaa ctcttggttt tgaaatccgt gcagttggtc ttaatccaca
     8521 tgcttcagaa tatgctggta tttctgccaa gcggactatt atcctatcta tgattatttc
     8581 aggtgccttg gcaggtcttg gtggagctgt tgaaggtttg ggaaccttcc agaacgtcta
     8641 tgttcaaggt tcgtcattag ctatcggatt taacggaatg gcggttagtt tgcttgcggc
     8701 caactcacca attggtatac tctttgcagc cttcctattt ggcgttctcc aagttggggc
     8761 tcctggtatg aatgctgcgc aggtaccatc tgagcttgtc agcattgtaa cagcgtctat
     8821 tatcttcttt gtcagtgttc attaccttat cgaacgcttt gttaaaccga aaaaacaagt
     8881 taaaggaggt aagtaaagat gtctattata accttgctcc ccctcttggt gtcttctatg
     8941 ctgatttact cagcacctct catctttaca agtatcggtg gtgttttctc tgaacgtggt
     9001 ggtgtggtaa acgttggcct tgaaggaatt atggttatgg gtgccttttc tggagttgtc
     9061 tttaaccttg aatttgcaga acaatttgga gcagcaactc catggctatc cttgcttgta
     9121 gcaggattgg ttggtagtgt tttctctatc atccacgcag cagcgacggt tcatttccgt
     9181 gcagaccatg ttgtcagcgg tacggtattg aacttgatgg cgcctgcctt ggctgttttc
     9241 ttagttaaag ttctttataa caaaggacaa accgacaacc taagtcaaac ttttggacgc
     9301 tttgatttcc cagtcttggc aaatatccca gtgattggtg atatcttctt caagtcaact
     9361 agtctacttg gttatctggc gattgccttc tcattccttg cttggtttat tctctttaag
     9421 actcaatttg gtcttcgtct ccgctctgtc ggtgaacatc ctcaagcagc ggataccttg
     9481 ggaatcaacg tctacaagat gagatattta gggattatta tttcaggttt tctaggtgga
     9541 attggcggag cgatttatgc gcaatcaatc tcagttaact tctcagtgac aactattgtt
     9601 ggacctggat ttatcgccct tgctgcgatg atctttggga aatggaatcc aatcggtgct
     9661 atgctttcta gtctcttctt tggactttca caaagtttgg ctgttatcgg ttctcaattg
     9721 ccgttcctac aaggagtgcc agcggtttat cttcaaattg caccttatgt tttgacaatt
     9781 cttgtcttag cagccttctt tggaaaagca gtcgcaccaa aagcagatgg tatcaactac
     9841 atcaaatcaa aataagcata caaaaaaacg tcagttcaat gactgaactg ccccccaaaa
     9901 gttagacaga aaaaatctaa cttttggggt gtttttatta tgaa
//
LOCUS       DAVKMJ010000060         9846 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000060 DAVKMJ010000000
VERSION     DAVKMJ010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9846
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.060"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            211..2139
                     /gene="glgB"
                     /locus_tag="VW348_001889"
     CDS             211..2139
                     /gene="glgB"
                     /locus_tag="VW348_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEU9746744.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEYGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRKDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFAERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATNITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
     gene            2129..3271
                     /locus_tag="VW348_001890"
     CDS             2129..3271
                     /locus_tag="VW348_001890"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEU9746745.1"
                     /translation="MKNEMLALILAGGQGTRLAKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGIDSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLELGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            3261..4400
                     /gene="glgD"
                     /locus_tag="VW348_001891"
     CDS             3261..4400
                     /gene="glgD"
                     /locus_tag="VW348_001891"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEU9746746.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            4397..5830
                     /gene="glgA"
                     /locus_tag="VW348_001892"
     CDS             4397..5830
                     /gene="glgA"
                     /locus_tag="VW348_001892"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEU9746747.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            5889..6260
                     /locus_tag="VW348_001893"
     CDS             5889..6260
                     /locus_tag="VW348_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HEU9746748.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVPGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            6300..6533
                     /locus_tag="VW348_001894"
     CDS             6300..6533
                     /locus_tag="VW348_001894"
                     /inference="COORDINATES: protein motif:HMM:NF019887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HEU9746749.1"
                     /translation="MISPQVKKETLEKWRKKLKLSKERTVAIGDGVNNLLMLKSAELG
                     IAFCSKEMLKKEIPHHVDKRDFLEVLPLIDCLE"
     gene            6542..7658
                     /locus_tag="VW348_001895"
                     /pseudo
     CDS             6542..7658
                     /locus_tag="VW348_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            complement(7655..8101)
                     /locus_tag="VW348_001896"
     CDS             complement(7655..8101)
                     /locus_tag="VW348_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEU9746750.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            8265..9569
                     /gene="eno"
                     /locus_tag="VW348_001897"
     CDS             8265..9569
                     /gene="eno"
                     /locus_tag="VW348_001897"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEU9746751.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFLGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
BASE COUNT         2953 a         1753 c         2173 g         2967 t
ORIGIN      
        1 tttgtcctgt tattatttca ttttactata gtagaaaaag aaaggtgttt tcgcaatttt
       61 ttgaaaaaat attgatttac aattgaacga gtaagtgaac ttgttgtaga ttttcaaaat
      121 aattaaagaa gtatagtaat ttacttgaat cttctctaaa aaggtagtat aataaaaaca
      181 tagaaaacgc ttacaggaga aagggagtat atggataata gagaagcatt aaaaaccttt
      241 atgacgggtg aaaattttta tctccaacat tatctaggag cacataggga agaactaaat
      301 ggagagtatg gctatacctt ccgtgtttgg gcacctaatg ctcaggctgt tcacttggtt
      361 ggtgatttta ccaattggat tgaaaatcag attccaatgg taagaaagga ctttggggtc
      421 tgggaagtct ttaccaatat ggctcaagaa gggcatattt acaaatatca tgtcacacgt
      481 caaaatggtc atcaactgat gaagattgac ccttttgctg tcaggtatga ggctcgtcca
      541 ggaacagggg caatcgtaac agagcttcct gataagaaat ggagggatgg actttggctg
      601 gcacgaagaa aacgttgggg ctttgctgaa cgtcctgtca atatttacga ggttcatgct
      661 ggctcttgga agagaaatcc tgatggcagt ccttatagtt ttgcccaatt gaaagatgaa
      721 ctcattcctt acctagttga gatgaactat actcatattg agtttatgcc cttgatgtcc
      781 cacccactag gtttgagttg ggggtaccag cttatgggtt acttcgcttt agagcatgcc
      841 tatggtagac cagaggagtt tcaagatttt gtcgaggagt gtcataccca taatattggg
      901 gttattgtgg actgggtacc aggtcacttt accatcaatg atgatgcctt agcctattat
      961 gatgggacac cgacttttga ataccaagac cataataagg ctcataacca tggttggggt
     1021 gcccttaatt ttgaccttgg aaaaaatgaa gtccagtcct tcttaatttc ttgcattaag
     1081 cattggattg atgtctatca tttggatggt attcgtgtgg atgctgttag caacatgctc
     1141 tatttggact atgatgatgc tccatggaca cctaataaag atggcggaaa tctcaactat
     1201 gaaggttatt atttccttca gcgcttgaat gaggttatta agttagaata tccagatgtg
     1261 atgatgattg cagaagaaag ttcgtctgcg accaatatta cgggaatgaa agagattggt
     1321 ggtctaggat ttgactacaa atggaacatg ggctggatga atgatatcct ccgtttctac
     1381 gaagaagatc cgatctatcg taagtatgac tttaacctgg tgactttcag ctttatgtat
     1441 gttttcaagg agaattatct cttgccattc tcgcacgatg aagtggttca tggcaagaag
     1501 agtatgatgc ataagatgtg gggagatcgt tacaatcaat tcgcaggctt gcgcaatctc
     1561 tatacgtacc aaatttgtca ccctggtaag aaattgctct tcatgggtag cgaatacggt
     1621 caattcctag aatggaaatc tgaagaacag ttggaatggt ctaacctaga agacccaatg
     1681 aatgctaaga tgaagtattt cacttctcag ctaaaccagt tttacaaaga tcatcgctgt
     1741 ctgtgggaaa ttgataccag ctatgatggt attgaaatca ttgatgcgga taatcgagac
     1801 cagagtgttc tttcctttat tcgtaagggt aaaaagggag aaatgttagt ctgtatcttt
     1861 aatatggtac ctgttgagcg gaaagatttt acaatcggac tacccgttgc aggaatttac
     1921 gaagaagtat ggaatactga gttggaagag tggggaggcg tttggaaaga acataatcaa
     1981 actgttcaaa cgcaagaagg actatggaaa gattatgagc agaccttaac ctttacccta
     2041 ccggctatgg gagcaagtgt atggaaaatc aaacgtcgct tgaaatctac taaaaccgtc
     2101 acaaataaaa accaaaaagg agtagaaaat gaaaaatgaa atgttagctt tgattcttgc
     2161 tggtgggcaa ggaactcgtc tcgctaaact cactcaaagc atcgcaaaac cagctgtgca
     2221 atttggtggg cgctaccgta tcattgactt tgccctatca aactgtgcca actcagggat
     2281 tcacaatgtt ggggtcgtta cacagtatca accacttgct ctcaacaacc atattgggaa
     2341 tggttcaagc tggggactag acggtattga ttcaggtgtc tctattcttc aaccttattc
     2401 tgcaagtgaa ggaaatcgtt ggtttgaggg gactagtcac gctatttacc aaaatatcga
     2461 ctatatcgac agtgtcaatc ctgagtatgt cttgattttg tctggggatc acatctacaa
     2521 aatggactat gatgatatgc tccagtctca taaggataat aatgccagct tgacagtagc
     2581 agttttagac gtccctctta aagaagcaag ccgttttggt atcatgaaca cagatgctaa
     2641 caatcgtatt gttgaatttg aagaaaaacc agctcaacct aaatctacaa aagcttctat
     2701 gggaatctac atttttgatt ggcaacgcct tcgtaatatg ttagtcgctg ctgaaaagag
     2761 caaggttggc atgtcagact ttggtaaaaa tgtcattcca aattaccttg agttaggtga
     2821 aagtgtttat gcttacgaat ttagtggtta ttggaaagat gttggtacta ttgagtcact
     2881 ttgggaagcg aacatggagt atatttctcc agaaaatgcc ttggatagtc gtaaccgtca
     2941 atggaagatt tactcaagaa acttgatttc accaccaaac ttcctcgggg caaatgctca
     3001 tgtggaagac tcattagttg tagacggatg tttcgttgat ggaactgtta aacattctat
     3061 cctttcaaca ggcgcgcaag ttcgcgaagg agcggaagtc cttgattcag ttatcatgag
     3121 tggagctatc attggtcaag gagctaagat taaacgtgcc attattggtg aaggtgcgat
     3181 tatttctgac ggtgtcgaaa ttgatggaac agatgaagta caagttgtag gatataatga
     3241 agtagtgggg gtagcaacag atgaagattg ataaatattc tgccatttta ggaaatacag
     3301 ttggttttca caatatgtcg acattgacgg accaccgtcc agtagcaagt ttgccatttg
     3361 gtgggaaata tcgtttgatt gatttcccac tttcaagcct tgctaatgca ggtgttcgta
     3421 gtgtctttgg tattttccag caggataata tcagctcagt atttgaccat attcgttcag
     3481 gacgcgagtg gggcttatca acccttctta gccattacta tctaggaatt tacaataccc
     3541 gtgtagaaag tagtacagtt ggaaaagaat actaccaaca gcttcttact tatttgaaac
     3601 gttctggctc aaaccaaacg gttgccctca actgcgatgt tcttattaac attgatttga
     3661 accaagtttt ccacctacat agtacaacaa aagagcctat cactgtagtt tataaaaaac
     3721 tagctaagaa agatatttca gaagtaaatg caatcttgga tgtagatgaa acagaccatg
     3781 ttctttctca taaactcttt gatagcaagt caacagctga aacgttcaat atgtctacag
     3841 atatctttgt cgttgataca ccttggttga ttgaacactt ggaagaagaa gctaaaaaag
     3901 aacatccaga gaaattgcgc tatgttttac gggatttggc tgtaaaagag ggagctttcg
     3961 cctacgagta cacgggctat ctagccaata ttcactctgt taaatcttat tatcaagcga
     4021 atatcgatat gcttgaatca caaaaattct attctctttt ctcaccaaac caaaagattt
     4081 atacaaaggt caaaaacgaa gagccaactt actatgctaa tacatctaag gtaagcactt
     4141 ctcagtttgc ctctggtagt attattgaag gtcaagtagc taattctgtt ctatcacgta
     4201 atattcatgt ccataaggat agcttggtta aagatagcct gctcttccct cgtgttgtta
     4261 ttggagaagg ggctcaggtc gaatatgcta tcttggacaa aggggttgaa gttgagcctg
     4321 gtgttgtgat tcgaggaact gcagaacatc cagttgtggt taagaaaggt gctaaagtaa
     4381 cagaggatat tcattcatga aaattttatt tgtagcagca gagggtgcac ccttttcaaa
     4441 aacaggtggt ttgggagacg tcattggcgc tcttccaaaa tcactggtaa aagctgggca
     4501 cgaagttgca gtgattttac cctactatga tatggtagag gctaaatttg gaaatcagat
     4561 tgaagatgtg cttcattttg aggtgagcgt tggttggcgc agacagtatt gtggaattaa
     4621 gaaaacagta ttaaatggtg taaccttcta ctttattgac aatcaatatt atttcttccg
     4681 tggtcatgtt tacggtgatt ttgatgacgg agaacgcttt gcctttttcc aactggctgc
     4741 cattgaggct atggaaagga ttgactttat tcctgatctt ctccatgttc atgactacca
     4801 tacagctatg attcctttct tgttgaagga aaaataccgt tggattcaag cctatgagga
     4861 cattgaaaca gttttaacca ttcataattt agaattccaa ggacaatttt cagaaggaat
     4921 gttgggtgat ttgtttggag ttggctttga acgttacgct gatggcaccc ttcgatggaa
     4981 caactgtctg aactggatga aggcaggtat tctctatgcg aaccgtgttt caaccgtttc
     5041 acctagctat gctcatgaaa ttatgactag tcagtttgga tgtaatttgg atcagattct
     5101 taaaatggag tctggtaaag tatctggtat cgtgaatggg attgatgctg atctttataa
     5161 tcctcagacg gatgctcttt tagactatca tttcaatcag gaagatttgt ctgggaaagc
     5221 caaaaataag gcaaaattgc aagaaagagt tggcttgcct gttagagcag acgttccact
     5281 ggtgggaatt gtttctcgtt tgacacgtca aaaaggtttt gatgtggtgg tcgaaagtct
     5341 tcaccatatc ttgcaagaag atgttcagat tgttcttttg ggaactggcg atccagcctt
     5401 tgaaggagct ttctcatggt ttgctcagat ttacccagac aagctatcaa caaatatcac
     5461 ttttgatgtc aaacttgctc aggaaatcta cgctgcttgt gacctcttcc tcatgccaag
     5521 tcgttttgaa ccgtgtggct tgtctcaaat gatggctatg cgttatggaa ccttgccatt
     5581 ggtccatgaa gttggaggct tgcgagatac agttcgcgct ttcaatccaa tcgaaggaag
     5641 cggtactggc tttagctttg acaatctatc tccttattgg ttaaattgga ctttccaaac
     5701 agcattggac ttgtatagaa accatccaga catttggaga aacctacaaa aacaagctat
     5761 ggagagtgac ttctcatggg atacagcctg caagtcatac cttgacttgt accatagttt
     5821 agttaattaa tagataaaat cgtatgatga cttcatacga tttttaggct gtttagagag
     5881 gagaactgat gtctcaagta aaaggcttgt gtgttttgga tgtagatgga accttaatcc
     5941 tagaagaagt gattgatctt ttagggagag aggcaggtca tgaggcggaa atttcgcaga
     6001 ttacaagtcg agcaatgcga ggagagttgg tctttgaaag cagtttaaga aaaagagtgt
     6061 ccttgttgga aggtcttcct attttggtct ttgataacgt cttcaactca attcatctat
     6121 cgctaaatgt cccagagttc atctctattc tccaaaagaa tggcatccta gttggtctgg
     6181 tgcctggtgg atttacacca atagttggag agattagcaa aatcccttgg tattgcctat
     6241 ttcactgcca accagcttga agtcaaagaa ggtttttaac aggaaaatta gttggacaaa
     6301 ttataagtcc ccaggtcaaa aaagaaactc tggaaaaatg gagaaagaaa ctaaaacttt
     6361 ctaaagaaag aacggtggca atcggtgatg gggtcaataa tctattaatg ttgaagtcgg
     6421 cggagttagg aatcgccttt tgttccaaag aaatgctcaa aaaagaaata ccacatcatg
     6481 ttgacaagag ggatttttta gaagttcttc ctttgattga ctgtttagaa tgagggaaaa
     6541 tatgaagatt gtaattgcac cggattcgtt taaggaaagc ttgacagctc aacaggtagc
     6601 tgaagcaata aaaagaggct tccaacaatc gatagcagat gtagaatatc tcctctgccc
     6661 tgttggtgat gggggagaag gtactgtaga tgctatccga cattctcttg acctaaaaga
     6721 aaaatggatc caagtgacag acccttttgg acaaaaagaa gccatgcgct attttcaaaa
     6781 aggggaactg gcactatttg aagtagctga cttggttggt cttggaaaaa ttccgctaga
     6841 gaaacgaaat ccacttcaaa tccaaacttg tggtattgga gagttgattc tccatctcat
     6901 ttctaaaggg attaaagata tttatatcgg tgttggtagc acggccagta atgatggagg
     6961 actggggatt gctgctggtt taggttatca attttatgat agggatggaa atgtcttgcc
     7021 tgcttccagt caatccttat taaacttagc ttctgtttca acagaaaatt gctataaaat
     7081 tcctgaaggt gttcaaattc atattctagc agatgtcgtg agtcccttat gtggtcatca
     7141 aggtgcgact tacacttttg gcaatcaaaa aggtctacat ccgactatgt ttgcagtcgt
     7201 agatcaggcg atccaagatt tttatgaaaa attctcacct gcaacattag aaattaaagg
     7261 agcaggagca ggtggaggcc ttgctggtgg tttgtgtgcc tttgctcagg caagtatcgt
     7321 gtctggaatt gataccttgc ttggacttaa tcaactttga taagaaagtt tcagatgctg
     7381 acttgcttgt tgttggagaa ggaagacttg acagtcaaag ctttgctggg aaagcgccta
     7441 taggtgttgc aaaaagaacc cctgttggag ttcctgttat tgctatttgc ggtagtcttg
     7501 ctgaagattt acctccccta ccatttgaaa atatccaagc tgtcttttct attttggaga
     7561 aaagtgaacc tttagaagat agtttgaaaa atgccagtct ctatctggag cgcacggctg
     7621 ccaatattgg gcacttatta aatatgtgca agatttagct aaaccatttc ttccataagg
     7681 atgttttggc tggttcttcc tttttaactt cccaaagttt tggaaaagca agtcgaaggt
     7741 ctttttcttc tacttgaact ggtgcattgc tatgaataac caggccaaaa ggagaagtaa
     7801 tatgctcttc agatactatg gtggcttgac tatcagtttc ttttgcttct tttaagtaga
     7861 aaacttgctt atcaaattcg atagttggtg aaatcttcac aaatagtggc tctgcttttt
     7921 cctgaaggtt ttctaaaata aataaaaagc ctttttctaa ctgagggcta tttgctgtgt
     7981 caatatctac atatccaaga actctttcct caaaagtacc aagatagcgt ctttgctcat
     8041 ccggatttat ttttaaccca ccatgagctt tttcaagtaa ttgttttgat aaatctgtca
     8101 tgaaaacagt atatcataaa agttagaata aaacagacaa aagaaagcga ttactttata
     8161 aagttaagga aaagttgcac aaagataacg ttttttcttg aaaaaggagg ggttttaagg
     8221 tattatagag gtgtaaaaaa tttaactcat aaggagagta aaaaatgtca attattactg
     8281 atgtttacgc tcgcgaagtc ctagactcac gcggtaaccc aacacttgaa gtagaagttt
     8341 acactgaatc aggtgctttc ggacgtggta tggttccatc aggagcttct actggtgaac
     8401 acgaagcagt tgaacttcgc gacggtgaca aatctcgtta cggtggtctt ggtacacaaa
     8461 aagctgttga caacgtaaac aacatcattg ctgaagctat cattggctac gatgtacgtg
     8521 atcaacaagc tattgaccgt gctatgatcg cacttgacgg tactcctaac aaaggtaaat
     8581 tgggtgcgaa tgcaatcctc ggtgtgtcta tcgctgtagc tcgtgctgct gctgactacc
     8641 ttgaaatccc actttacagc taccttggtg gattcaacac taaagttctt ccaactccaa
     8701 tgatgaacat catcaacggt ggttctcact ctgacgctcc aatcgctttc caagagttca
     8761 tgatcttgcc agttggtgcg ccaacattta aagaagccct tcgttacggt gctgaaatct
     8821 tccacgctct taagaaaatc cttaaatcac gtggtttgga aactgccgta ggtgacgaag
     8881 gtggattcgc tcctcgtttc gaaggaactg aagatggtgt tgaaactatc cttgctgcga
     8941 ttgaagctgc tggatatgta ccaggtaaag acgtatttct cggatttgac tgtgcttcat
     9001 cagaattcta cgataaagaa cgtaaagttt acgactacac taaatttgaa ggcgaaggtg
     9061 ctgctgttcg tacatctgca gaacaaatcg actaccttga agaattggtt aacaaatacc
     9121 caatcatcac tattgaagat ggtatggatg aaaacgactg ggatggttgg aaagctctta
     9181 ctgaacgtct tggtaagaaa gtacaacttg ttggtgacga cttcttcgta acaaacactg
     9241 actaccttgc acgtggtatc caagaaggtg ctgctaactc aatccttatc aaagttaacc
     9301 aaatcggtac tcttactgaa acttttgaag ctatcgaaat ggctaaagaa gctggttaca
     9361 ctgctgttgt atcacaccgt tcaggtgaaa ctgaagattc aacaatcgct gatatcgcag
     9421 ttgcaactaa cgcaggacaa atcaagactg gttcactttc acgtacagac cgtatcgcta
     9481 aatacaacca attgcttcgt atcgaagacc aacttggtga agtagctgaa tatcgtggat
     9541 tgaaatcatt ctacaacctt aaaaaataaa atagttcagt gaactatttt atcccgaacc
     9601 atgaaattca aaagttcggc cgttgattta acaacgtttc tagcccctcg gattttatcc
     9661 gaagggctat ttttgtattt agagggcaaa aaagggacaa aactttttgg ctctttgtca
     9721 actgtagtgg gttgaagtca gctaagctcg agaaaggaca aaattcgtcc tttctttttt
     9781 gatgttcaga gcgataaaaa tccgtttttt gaagttttca aagttccgaa aaccaaaggc
     9841 attgcg
//
LOCUS       DAVKMJ010000061         9032 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000061 DAVKMJ010000000
VERSION     DAVKMJ010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9032
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.061"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(299..1147)
                     /gene="dprA"
                     /locus_tag="VW348_001898"
     CDS             complement(299..1147)
                     /gene="dprA"
                     /locus_tag="VW348_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEU9746752.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLLTSGQDV
                     LAEFEF"
     gene            complement(1243..1932)
                     /locus_tag="VW348_001899"
     CDS             complement(1243..1932)
                     /locus_tag="VW348_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEU9746753.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            complement(1944..2822)
                     /locus_tag="VW348_001900"
     CDS             complement(1944..2822)
                     /locus_tag="VW348_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEU9746754.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2812..3681)
                     /gene="licA"
                     /locus_tag="VW348_001901"
     CDS             complement(2812..3681)
                     /gene="licA"
                     /locus_tag="VW348_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEU9746755.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            complement(3698..4720)
                     /locus_tag="VW348_001902"
     CDS             complement(3698..4720)
                     /locus_tag="VW348_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEU9746756.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4725..5432)
                     /locus_tag="VW348_001903"
     CDS             complement(4725..5432)
                     /locus_tag="VW348_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEU9746757.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGNRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5768..7255
                     /gene="tacF"
                     /locus_tag="VW348_001904"
     CDS             5768..7255
                     /gene="tacF"
                     /locus_tag="VW348_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEU9746758.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVVPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7265..8068
                     /locus_tag="VW348_001905"
     CDS             7265..8068
                     /locus_tag="VW348_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU9746759.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8070..8879
                     /locus_tag="VW348_001906"
     CDS             8070..8879
                     /locus_tag="VW348_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEU9746760.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
BASE COUNT         2838 a         1815 c         1527 g         2852 t
ORIGIN      
        1 caaagcgcaa actaggaagc tagccacagg ttgctcaaag cactgctttg aggttgtaga
       61 taagactgac gaactcagct caaaatactg ttttgaggtt gcagatggaa gctgacgtag
      121 tttgaagaga ttttcgaaga gtattatatg agaaaaatcc tctactctac taatccactt
      181 agaaaaaacg catattagca agtgttaaaa acttgctaat atgcgtttta ttatggaaat
      241 gttgggttca ttttctctta aaattgattt tttcttagaa ttctagctta ggtcattttt
      301 aaaattcaaa ttccgcaaga acatcttgcc cactggtgag caattttgct ccttcttgaa
      361 tcaaatgatg gcaaccgtct gatagtccat ctaaaatgct accaggaata gcaaagacat
      421 cgcgtccttc ttccattgct cgctcacacg taatgagact acctgaacgc atcttagcct
      481 ctgctacaat cacaccacga caaagtccag caatgatgcg attacgggca ggaaaatgaa
      541 atttcagagg ttgttcgcca ggtccatatt cacttagaac cagatggtca ttgccgatgt
      601 agtcttgcaa gcgtttattg gctttaggat aaaacacatc cagtcctgtt ccaatcactg
      661 caatggtttt tccgccattc tgaagagctg ccatatgagc tgctgtgtca atgcccttgg
      721 ccagaccact gacaataacc agttcatttt ccaagccttg aatgactttt tcaactgact
      781 tagctccctg tttgctacaa gcacgactgc ccacgaccgc taccttcggg aatttcagga
      841 ggtcaagatt tcccttgtaa aataaaagta caggcgcatc atatatttca ctcaaatccc
      901 aaggataaca gtcatctaaa atagagaaag atggaaattt ttgaaactct ttcgacaaat
      961 gcgcatcgtc tatctgaaaa taacgttcca taaaaacggc tggattacgg caacctgata
     1021 tatctgcaat atcacccaac aaaagctcct gatcaacatt ttcaccgtat tctagcactt
     1081 tcaaaatctg ttgattggtc aaacctgatt tttttaactt atagatttca tagtttgtga
     1141 ttttcataaa taactccatt tctttttcta ctcatctatc tattcgtaaa agttcgtaaa
     1201 aaatcaaaaa acatccgact attttgtcag atgttggaat ctttaatttt cgtttttaag
     1261 aatttcttct aatttacgat agtcttggac actatcgatc tcataaatgc tattgccttc
     1321 taattcttca acatagacat ctagctcttt gatattatcc ttaaccatat tgtcccaata
     1381 gagatcaaca aattcaccac ttgcataagc cttgtcgata aagctgacaa tcttttctgc
     1441 agttggagca tcccagaagg atacaccact aaggatgcga cctgccttgc tatcaacaat
     1501 aatgtcttga accttgtagt catctccata gaccaagaac cattcgttgg tacaatcttc
     1561 acgataaaca ctaaaataag tcgaacgtgt caaatcattg cggaacatat ttttaaagag
     1621 ataattgtca gcatcaataa catagctgtt ggccaattct tcttttacaa gatagagaga
     1681 gtaaaagtta ttgtagtcag cgtatttatc attgaaaacg aggcgaacac cgtatttttc
     1741 ttttaagtaa tcgaattgtt ctttaagata accaacaatg atgatgatgt cattgattcc
     1801 tttttctttg agaaactcaa tttggtattc aatcaaaggt ttttgattaa cctgaaccaa
     1861 ggctttaggg gtattttcag tcataggacg caagcgagtt cccaatcccg ctgctaagat
     1921 aatggctttc acacgaatct cctttattct ttaataataa tataaactcc agcaatgacg
     1981 acaagtgacg tcataatggt cagcatatct agcggtgcac ccaaaaaaac aactgcaaac
     2041 aagaccgtcc atactacata gctcacgttc aagcctgtag ccttggctgg ttgcaagcga
     2101 ttgatagcga tataataagc caagtaggaa atcatatcaa aggctgcaaa aacaatcatg
     2161 agacctagca attgtccatt ggctactgca gtaaatgact gatgagagaa gagcacaatc
     2221 acaagatagg acaagaacga agtcacttga cggattaaga gggcttcgat ttcactcagt
     2281 tcactttcca tagcaaagga gctaagaaca ctctcacttc cccatgcaat agcacaaacc
     2341 aaagcacaga gaatcccaat gtagaaggaa ttaacctgtt caaccttata ggtctgggca
     2401 ataatccctc caataatcaa gacaatccca aatacagtat ttttcgaaat cttgtgcttc
     2461 aaaaagaaga aagccaatag aactgaaatc gcagggtaaa tagccgatac agatgaagct
     2521 aaagaacttc cgatatactt aactgcataa agattggcct gcataccgat agggcctgct
     2581 agcaaggctc cgatgataac actgacattg cgaatattta agaaaattga gaggcgaact
     2641 ttcccttctt ttaccaagag aaaagctagt aagataaaga tgctcaaaaa atcatgagct
     2701 gcagccacca caaagggtga caaatctgta aaaatcgaaa agatataagc actaaccgtt
     2761 agacccaagc cccagaaaat acctgagaga aggccaaaag gaactccgtt tttacttttc
     2821 atctgaacct ccataagaag ccaaaccttt aacagctctt tggtaacgat tcacaccata
     2881 gtcaccaaaa tcttcacctt gctcttcctt atagacagtc catagactcc aaatagtatc
     2941 ttgtaaaatt ttataaatag caatcttttc atgagaaacc ggtgtttggt cactctcata
     3001 gtgagataag aaagtttctt cctcttggga agtgaattca gactctaaaa agagggcagc
     3061 caaatcccac attggatcat tcattgatga atattcccag tcaatcaaat aaagtcgtcc
     3121 ttgaggtgat tcgataaagt tttcaggcac caaatcgata tgacaagatt ttctgtcaac
     3181 acctaagtca gccagtcttt tctctaagga gaagactgca tttctaacag attcatagtt
     3241 ggcataagga atttgttctt caatcaagga ttcgtatttt ttgatttctt caaaaggagc
     3301 aaattctcct cttaattcct tagcagacgt atgaatagtt tgtaatattg gagcaatttt
     3361 gtcgaacttg gtcttgattg acgttgaatc aagcgtaatc gcagattcga tatactcatt
     3421 tactttgata ccagcttcaa tatcaaaaag ataatttttt acatctaagc ctaaatcctt
     3481 tagtagttca agattgtact tttcatcttg tcgattgata agcttttctg tccctttacc
     3541 aaagaattta acaatgtatt gcttatttgt tgttttggcc aaatagtttt gattggtcat
     3601 tccacccagt tgttcaacac tgaggacttc ctcttcttga ctaagtaagg aagaaatttt
     3661 ttctttaatg attttctcca caattaacct ccagtactta tacttcccac ttaaacactg
     3721 ttttaaaggc tgtgtttaaa tcggttgcaa agacacgatg aatatcttta atttctctta
     3781 caggttcttc tagataaagg atatttttaa gacgattggc aaatttcttg acttccatca
     3841 tttggatagc atttttaaaa tcaatgcgac cagaacgaga tgacccaacc aaaatcaagc
     3901 ccttttctaa ggcatcgcga gtattgagat tgactttata ttcgctaact cccatcatga
     3961 gaatcgttcc ctgaggacga atgtagcgaa tcaagtcatt aatagctggt ccagtaccat
     4021 caccaccaca acattcaaaa gcatggtcaa aggccaactc ttcaggaata ttatccgtaa
     4081 tatagcattc tttggcaaat gagaagagtt ccaacttttc ccaatgacga ccaataacca
     4141 caatctctga ttctggcaaa gtatagttga taatattggc aaccacaaaa gctaaacttc
     4201 catctccaat aacggcgatc cgctcccgct tgctatgagc aagagtcaat agacgattca
     4261 tagcgtgcat gcccacactg acaaactctg taatggctgc aaccgtatct tcaatagcat
     4321 cataagccac cacacgatct ttagggagag aaacaaactc tctcataaag ccatcaaatc
     4381 cactagacaa gaaatgggtc cctgtcatgt agttttcata gaattcttca tcactctgca
     4441 taggagactg attgggaatc atgacaactt tttgaccaac ctcgtaggtt ccggtcgggt
     4501 cagaaatgac ggttccacat gactcgtgaa tcattgccat tggaagcttt ttattcaaaa
     4561 tcttgggatc acgttttccc tgatagtaac gctgatccgc atgacagaca gccatgtagt
     4621 tgggacggat aaggatatga ttctcttggt caatagcctc ttcctgatat ttgacattga
     4681 taaacttagg cttagttagt tgataaattt gattaatcat tttactagtc tttctcaatc
     4741 atactttttg caatcttcaa atctgttacg gttgtaatct tcagatttga gtattcacct
     4801 ttggccaagg ccacatcttt tcctttgatc acaaagattt tacatgcatc tgtcaagatt
     4861 tccttctctt catcagaaag agatccataa aggtccatga agtccttgca acggaatgtt
     4921 tgaggtgttt gtccttgata aaggtgagca cgatttggaa tatctgtaat aaattgacca
     4981 ttggtacttt caacgatagt atcaaccgct tctaccactg tgtccactgc gtcatgattt
     5041 tgggcaagtt ggatattgtc ctgaatcatg cgaagtgtaa taaatggacg aacagaatcg
     5101 tgggtaacaa cgatatcctc tggagtaagc ggacgataag catcaatggc ttcaatgatt
     5161 ttcttaatac ttgtattgcg gtcagcacca ccctttgtaa tgatgatacg ttccttataa
     5221 agaggaagat atttatctac aagatcttct gcatgagaaa cccagtctcc atgaacacca
     5281 actacaattt tttcaatact tggctccaag acaaattttt caattgtatg aatcaaaata
     5341 ggtcgattac ctagctctaa aaattgtttt ggcaagttac tgatccccat gcgtgtgcca
     5401 gttccaccgg caagaattcc tgcataaatc atctattttc tcctttgtct tactaaaaaa
     5461 acttattctc tctattatac cacaatctag tcctatcata aaagaaatac tggtcctccc
     5521 cttctagaat aggagaatta tgcagttcta ttattcaaag aaactagtcc atttctagta
     5581 atgactagga attctgtagc aattactaat aaatggctgc gaaattttag agtccttcag
     5641 aataatatac tttccttaaa gaaaacttaa aacttaagat ttgaaacttc aaagtgatta
     5701 cttgacttac tgcccttcat ttcttattag ctaactttat gatataatga aaaacgaggt
     5761 aaattgaatg aaaagtataa aattaaatgc tctatcttac atgggaattc gtgtcttgaa
     5821 tattattttt cccatcctaa ctggaaccta tgtcgcgcgt gtcttggacc gaactgacta
     5881 tggttacttc aactcagtcg acactatttt gtcatttttc ttgccctttg caacttatgg
     5941 tgtctataac tacggtttaa gggctatcag taatgtcaag gataacaaaa aagatcttaa
     6001 cagaaccttt tctagtcttt tttatttgtg catcgcttgt acgattttga ccactgctgt
     6061 ctatatccta gcctatcctc tcttctttat tgataatcca atcgtcaaaa aggtctacct
     6121 tgttatgggg attcaactca ttgcccagat tttttcaatc gaatgggtca atgaagctct
     6181 ggaaaattac agttttctct tttacaaaac tgccttcatc cgtatcctga tgctggtctc
     6241 tattttctta tttgttaaaa atgaacacga tattgttgtc tatacacttg tgatgagttt
     6301 atcgacgctg attaactacc tgattagtta tttttggatt aaaagagaca tcaaacttgt
     6361 taagattcac ctaagtgatt ttaaaccact ctttctccct ctgacagcca tgttagtctt
     6421 tgccaatgcc aatatgctct tcactttttt agatcgcctc ttcctcgtta aaacagggat
     6481 tgatgtcaac gttagttact ataccatagc tcagcgaatt gtgaccgtta tagctggggt
     6541 tgtaacaggt gcaattggag tgagtgtgcc tcgtctcagt tactatctgg ggaaaggaga
     6601 caaagaagcc tatgtttctc tggttaatag aggtagtcga atctttaact tctttatcat
     6661 tccactgagt tttggactca tggttttagg accaaatgcc atcctacttt acggtagtga
     6721 aaaatatatc ggaggcggca tcttgacctc tctcttcgct tttcgtacga ttatcctggc
     6781 cttagatacc attcttggtt cccaaattct ctttaccaat ggctatgaaa aacgtatcac
     6841 agtctataca gtctttgctg ggctactcaa tttgggcttg aatagtctcc tctttttcaa
     6901 ccatatcgtg gttcctgaat actacttact gacaactatg ttatcagaga cttctctact
     6961 tgttttctat attattttca tccatagaaa acaactcatc cacttgggac atatctttag
     7021 ctatactgtt cgatactctc tcttttcact ttcctttgta gcaatttatt tcctgattaa
     7081 tttcgtgtat cctgtggata tggtcattaa tttgccattt ttaattaata ctggtttgat
     7141 tgtcttgcta tcagctatct cttatattag tctacttgtc ttcacaaaag atagcatttt
     7201 ctatgaattt ttaaaccatg tcctagcctt aaaaaataaa ttcaaaaaat cataggagtt
     7261 taaaatgaaa caactaacca ttgaagatgc caaacaaatt gaattagaaa ttttggatta
     7321 tattgatact ctctgtaaaa agcacaatat caactatatt attaactacg gtactctgat
     7381 tggggcggtt cgacatgagg gctttatccc ttgggacgac gatattgatt tatccatgcc
     7441 tagagaagac taccaacgat ttattaacat ttttcaaaag gaaaaaagca agtataagct
     7501 cctatcctta gaaactgata agaactactt taacaacttt atcaagataa ccgacagtac
     7561 gactaaaatt attgatactc gaaatacaaa aacctatgag tctggtatct ttatcgatat
     7621 tttccctata gatcgctttg atgatcctaa ggtcattgat acttgttata aactggaaag
     7681 cttcaaactg ctgtctttca gtaaacataa aaatattgtc tataaggata gccttttaaa
     7741 agattggata cgaacagcct tttggttgct ccttcgaccg gtttctcctc gttattttgc
     7801 aaataaaatc gagaaagaaa ttcaaaaata tagtcgtgaa aatgggcagt atatggcttt
     7861 tattccttca aaatttaagg aaaaggaagt cttcccaagt ggtacctttg ataaaacaat
     7921 cgatttaccc tttgagaatt taagccttcc tgcacctgaa aaatttgata ctattttgac
     7981 acaattttat ggagattata tgaccctacc accagaagaa aaacgcttct acagtcatga
     8041 atttcacgct tataaattgg aggattagga tgcaatattt agaaaaaaaa gaaattaaag
     8101 aaattcaact agccctgctg gactatattg atgagacttg taagaaacat gatattcctt
     8161 attttctcag ttatggaacc atgcttggag ccatccgcca caaaggtatg attccttggg
     8221 atgatgatat tgatatttcc ctttatcgtg aggattatga gcgtttactg aagattattg
     8281 aagaagaaaa tcaccctcgc tacaaggttc tttcctacga tacatcttct tggtacttcc
     8341 ataatttcgc atcgattttg gacacttcta ctgttataga agaccatgtt aagtacaagc
     8401 gtcatgatac cagccttttc atcgatgtct tcccaattga tcgatttaca gacttgagca
     8461 ttgtcgacaa gagctataag tatgtggccc ttcgtcaact agcttatatc aaaaaatcac
     8521 gagcagttca cggtgatagc aaactaaaag attttcttag attatgtagc tggtacgctc
     8581 tccgatttgt caatcctcgc tacttttaca agaaaattga tcaactagtc aaaaatgctg
     8641 taaccaacac tcctcaatat gaaggaggag ttgggatcgg taaggaaggg atgaaagaaa
     8701 tcttcccagt tgataccttt aaagaactga ttttaactga gtttgagggc cgtatgttgc
     8761 ctgttcccaa aaaatatgac caatttttaa cccagatgta tggcgattat atgacaccac
     8821 catcaaaaga aatgcaagag tggtatagtc atagcattaa agcttatcgc aaaaactgat
     8881 tgagggggat tatacaaact actaagatag aggttattca aaaacataat tttagtagaa
     8941 aatgaaatat atattcccac aataaaacgc atcatatcaa ggtttttgaa aaaccttgat
     9001 atgatgcgtt ttataatttt aaagactttt tt
//
LOCUS       DAVKMJ010000062         8821 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000062 DAVKMJ010000000
VERSION     DAVKMJ010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8821
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.062"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            181..978
                     /locus_tag="VW348_001907"
     CDS             181..978
                     /locus_tag="VW348_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001056933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEU9746761.1"
                     /translation="MNMNLNTNEILTTTEYDMFRKISNRKITENPKLEEELLSEGQRQ
                     PILVNEKMEVIDGQHRLYYLRKHRKPVRYIIDPTANFKTVISMNTSAVNWALQDYVYS
                     FALEGDPEFVKLAKFLDENELLSDKMVIVAGSGRRDGTAAHVVKKLKKGDYVFSNEKQ
                     LREFCKFYERVLNETKLPNKPFLQSVLWTLYTTSVFDENRMLTQLKKSDLTSEDIEGF
                     AKKKLLLTFLELYNGRWSDDHPSLIQYFINRKGSLTIPSLPKQDEDN"
     gene            996..1133
                     /locus_tag="VW348_001908"
     CDS             996..1133
                     /locus_tag="VW348_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746762.1"
                     /translation="MKVTVYVYGRKLEPDEPIIIPENHRFYDIWNGIVNEMLDNEEDV
                     A"
     gene            1133..1354
                     /locus_tag="VW348_001909"
     CDS             1133..1354
                     /locus_tag="VW348_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746763.1"
                     /translation="MKLLTKLKLRLEGVLKSVNLDWREVAVELMNDLFEERKRRFAFE
                     QENYDLKQELAAYKYKENFDIKARLQGEM"
     gene            1355..1609
                     /locus_tag="VW348_001910"
     CDS             1355..1609
                     /locus_tag="VW348_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746764.1"
                     /translation="MYIISIYVKNTETGNEDFSLIGRDFLPTGHQDYIARVFGTKEEA
                     IDYLKSISYIASGVHGNDWVYQNEKLPEIESRCRIWKVGE"
     gene            1622..1882
                     /locus_tag="VW348_001911"
     CDS             1622..1882
                     /locus_tag="VW348_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746765.1"
                     /translation="MFKALKTIKKIKQLQKEMHAFSLAFLALQDMGLMPETERSKAKA
                     QTMHDVSRVLKDVLDGKSVDEAIKRLNSEVKAEEVGQKDDQN"
     gene            2152..2970
                     /gene="bet"
                     /locus_tag="VW348_001912"
     CDS             2152..2970
                     /gene="bet"
                     /locus_tag="VW348_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage recombination protein Bet"
                     /protein_id="HEU9746766.1"
                     /translation="MTNNQIVEAKGDFLTNPQLLNSGIIRKYLDPQGKASDEELAYFI
                     AQAKAQNLNPFTKEIYFIKYGTQPAQIVTAKSAFEKKADSHPQFDGKEAGVIYLMDGE
                     IKYSKGAFIPKGAEILGGWAKVYRKDRTYPTETEVSFEEYDNSKIRARVKELTQQGKD
                     VTYPVMNSYGKPIGENNWDTMPCVMIRKVALVSAYREAFPAELGASYEADEIQLDNTP
                     KDVTPQESREDVVARKMAQIEQFNKEQEANHADPEPAKTEEPIQGELLDGELEY"
     gene            2980..4068
                     /locus_tag="VW348_001913"
     CDS             2980..4068
                     /locus_tag="VW348_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001157034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEU9746767.1"
                     /translation="MQELQVIDDKKINKIYEMITTDELTRESFEKDLIEATEKYKDYI
                     PTAGTLKDDKAKRAEFNKLIESKNRIRIDTKNLLSETANTWDSYAKSIIDPFATVVSE
                     FDKGIKEIEEHQRQLKIDTVKSYLANKSAEYMLDPRLFDEKALEYVKAGDFMADGVTL
                     KKATMKSLDDMVTFEFQKQQEFEKAKSAISGLCAEYGMTDSPYIRQLKDLTLAEAFEQ
                     IKADYEFEKQKEEIRQAQERAERESQELLAAQQTKQQERAPKSTGTPNFDPEAGEILD
                     GEQIPQNEQNSLRGAENDLKRYTQKMTLEVYFVDTAEKDRFKAGLSQLGFDFKKNYQV
                     SGYQRIEPLTQAELNEQWGGNHGHQKNI"
     gene            4046..4369
                     /locus_tag="VW348_001914"
     CDS             4046..4369
                     /locus_tag="VW348_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746768.1"
                     /translation="MDIRKISDSVAIYSDGKKLHVIHNLGDEFILDFKVGEDSVWNLN
                     GQVVEIIDMIEPVFKVFSFCSKSGEGMQRLKHAIVHFEIFEQYIRDNQEDLMIWWHNP
                     GGEYD"
     gene            4362..4697
                     /locus_tag="VW348_001915"
     CDS             4362..4697
                     /locus_tag="VW348_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein Cse60"
                     /protein_id="HEU9746769.1"
                     /translation="MIKTVFFSCDYPHHEAIDDQINSWLAENPGIKLIDIKFQSNVSA
                     VADSGVSAEYWHTSALIIYKVPSENNISSINSNGLGFIISCEKCGSLSIIKGKDVGQN
                     VCYECKGEK"
     gene            4792..5208
                     /gene="ssb"
                     /locus_tag="VW348_001916"
     CDS             4792..5208
                     /gene="ssb"
                     /locus_tag="VW348_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEU9746770.1"
                     /translation="MINNVTLVGRLVAPPDLRKTPNNVSSLQGTLAVNRNFKNENGER
                     EADFINFKAWRGTADIIAQYCSKGSLIGIIGRLQVRSYEKDGQRRYVTEVIAESVALL
                     ESRNSQHGQGNSFQNGNSSPFTDPNPFDLPNDGLPF"
     gene            5221..5916
                     /locus_tag="VW348_001917"
     CDS             5221..5916
                     /locus_tag="VW348_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEU9746771.1"
                     /translation="MEIDKIIKKDVLEFMETIPDNKIDLIVTDPPYLINYKTNWRKEK
                     HKFSNVIKNDNNPELIKEYIKECYRILKDDTAIYIFCSFDKVDFFKKEIEKYFSVKNI
                     IIWRKNNHTAGDLEAQFGKQYEMIILANKGRKKFNGERLTDVWDFKRVSSDKLLHQNQ
                     KPIELIKRCIVKHPDVGDTVFDGFMGSGTTALAALETDRHFIGTEIDEYYFGIAEERI
                     KNHNAQLSLFDEV"
     gene            5918..6127
                     /locus_tag="VW348_001918"
     CDS             5918..6127
                     /locus_tag="VW348_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746772.1"
                     /translation="MEWTDWVDWKPETKTDIKTKIENDGYTFPHYDKKNNGVKYVIST
                     LDIKRDCLRLGVPFEDVYPLQTTLF"
     gene            6141..6470
                     /locus_tag="VW348_001919"
     CDS             6141..6470
                     /locus_tag="VW348_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746773.1"
                     /translation="MASKINATERIAIIIDKQKIEVVTTLNYDMSISFDNKDTAPTLD
                     DNGDLFEPVYKCKVKAIPKNDVFFTSLTRVKSNIKTLQEVKKFFEFVNENRENLFEMA
                     GFKGALE"
     gene            6467..6898
                     /locus_tag="VW348_001920"
     CDS             6467..6898
                     /locus_tag="VW348_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HEU9746774.1"
                     /translation="MKLTLNIEPKPQSRPRFARRGSFTTTYEDKDMKTWRNHCQLLIA
                     NQYMGQPILEGALRARLRFYIKPPQYISKVKKNQQALLDEIIPVGKKPDIDNYEKALY
                     DSMSGIVFQDDGQIALHDVGKFYSLNPRIEVEIEVMKSLSI"
     gene            6914..7096
                     /locus_tag="VW348_001921"
     CDS             6914..7096
                     /locus_tag="VW348_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000796349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746775.1"
                     /translation="MADYALYQGDVFVTLGTLAQISSETGITERMLKYYTYTSHQRRH
                     PNGRAVIKIEEEDNEN"
     gene            7121..7438
                     /locus_tag="VW348_001922"
     CDS             7121..7438
                     /locus_tag="VW348_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746776.1"
                     /translation="MMEELKQKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKGWLPKSKEFDDWIGYSPSMAQVVIAVYLIY
                     GGN"
     gene            7440..7928
                     /locus_tag="VW348_001923"
     CDS             7440..7928
                     /locus_tag="VW348_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEU9746777.1"
                     /translation="MNKQELIEKYKKLEGVWNAEGAELARQIFLQDLEQLDKPKPVKV
                     PQCVAEYIEFKKKNNFHVYGAMRVIEDHYDKKVPEWFYENNIEKFCLAWLDGYEVEKE
                     KRYLVTLKNRQPLVKSQSGSTLYFSQDITARNYKGTQKELEDANFGWVFDCPGIEIEE
                     VE"
     gene            8086..8346
                     /locus_tag="VW348_001924"
     CDS             8086..8346
                     /locus_tag="VW348_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1372 family protein"
                     /protein_id="HEU9746778.1"
                     /translation="MKRFIAIWILLSAGLNIWQSIYIKKLEEKRPIVVYKADNAGAEI
                     FGKVVEKGRHGKLYTLTIRDYGVFVVTKDVYDKVKVGDEVLL"
     gene            8343..8765
                     /locus_tag="VW348_001925"
     CDS             8343..8765
                     /locus_tag="VW348_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746779.1"
                     /translation="MTETIKLPDYYEPDWKNARYGSLEELKELLLFKRIVKWDKDFLL
                     LEDGTKVTIEMSESDCCASAGGEFQDVSLDAVITNIEIGEPEEIPDHWGTGYKNKVTI
                     FHNQNPVAIANCEAEHNGYYYSVCSLVIGDIHFPVVNA"
BASE COUNT         3107 a         1472 c         2002 g         2240 t
ORIGIN      
        1 tacttcatca gcgaatctac aacgtacaga gaagctaaaa tagcgtgtga gaagctattg
       61 aaacaagtca gccatgagat agaactcagg gcaatggaaa gtaagacagt ctagaagaca
      121 acaaaaagca cctgacggca atcaggcgca tactaaaaaa ctttacaaga ggattataac
      181 atgaatatga acttaaatac aaatgaaatt ttaacaacta ctgaatatga tatgtttcgc
      241 aaaattagta atagaaaaat aactgaaaat cctaaattgg aagaggagct actttctgag
      301 ggacaacgtc agccgatttt ggtaaatgaa aaaatggaag ttatcgacgg gcaacatcgt
      361 ctttattact tgagaaaaca tagaaaacca gtgcgctaca taattgatcc gaccgctaat
      421 ttcaagacag taatttcgat gaatacatca gctgtcaact gggcattaca agattatgtg
      481 tattcgttcg ctttagaggg agatcctgaa tttgttaaat tagctaaatt tttagacgag
      541 aacgaattgc ttagtgacaa gatggtaatc gtagctggtt caggaagacg tgatggtacg
      601 gcagcacacg tagtcaaaaa attaaaaaaa ggcgattatg tattttcaaa cgaaaaacag
      661 ttaagagaat tttgtaagtt ctacgaacgc gttttaaacg aaacaaaact gcctaacaaa
      721 ccatttttac aatctgtttt atggactttg tatacaacat cagtttttga tgaaaacaga
      781 atgttgacac aattgaagaa atcagatttg acatcagaag atatcgaagg atttgcaaag
      841 aaaaaattgc tattaacttt tttagagcta tacaacggaa gatggagtga cgatcatcct
      901 tctttaattc aatactttat caacagaaaa gggtcgttaa caattcctag tttgcctaaa
      961 caagatgaag ataattaaaa aagtaggaag ataaaatgaa agtcacagta tatgtttacg
     1021 gccgaaaatt agaaccagat gaaccaatta tcatcccaga aaatcatcgt ttttatgaca
     1081 tttggaacgg aattgtaaat gaaatgctcg acaacgagga ggatgtagct taatgaaact
     1141 acttactaaa ttaaaactca gactcgaagg agttcttaaa tcagtcaacc ttgactggag
     1201 agaggtagca gtcgaactta tgaacgacct atttgaggag cgcaagcgtc gctttgcttt
     1261 cgagcaagaa aactatgact tgaagcagga gcttgctgcc tacaagtaca aagaaaactt
     1321 tgatatcaag gctagactgc aaggagaaat gtagatgtac attatatcga tttatgtcaa
     1381 gaatactgaa actggaaacg aggatttcag tttgattgga cgtgatttct taccgacggg
     1441 gcaccaagac tatattgcaa gagtttttgg aacaaaagaa gaagcgattg attacttaaa
     1501 atctatatct tacatcgcat caggtgttca tggtaacgat tgggtttatc aaaatgaaaa
     1561 actaccagaa attgagtcac gttgccgaat ttggaaagta ggagaataaa aggagaacaa
     1621 tatgtttaaa gcactaaaaa caatcaaaaa aatcaaacaa cttcagaaag aaatgcacgc
     1681 tttcagcctt gcgtttctag ctctacaaga tatgggcttg atgccagaaa ctgaaagaag
     1741 taaggcaaag gctcaaacaa tgcacgatgt aagccgcgta ctcaaggacg tcttggacgg
     1801 caagtcggta gatgaagcga taaagcgtct aaatagcgaa gtgaaagctg aagaggtggg
     1861 gcagaaagat gaccagaatt gaacttgaaa accgtgtatg gcttttggct aatcatgaag
     1921 aaaaaaacga attgctggat cttgggctaa cgtcaaagac cagatatgtg aagcgagttc
     1981 tggaactagg aaaggtgtat gctcatgttt gattatgaca gagatataat gcaaccgcct
     2041 gaagaacgag aagaacgtga cccagctgat tggattttca gcgctggtca atggatctat
     2101 gtaggagatt gttagcctat gaatagagaa cacaacgaaa ggtagaagga aatgacgaat
     2161 aatcaaattg tagaagcaaa aggcgacttt ttaaccaacc cacagctact taatagcggt
     2221 attatcagaa agtatcttga cccacaagga aaagctagtg atgaggagct tgcctatttt
     2281 atagctcaag ccaaagccca aaacctcaat ccatttacaa aagaaattta ttttatcaag
     2341 tatggaactc agccagccca gatagtcact gccaaatcag cttttgaaaa gaaagcagat
     2401 agtcacccgc aatttgatgg caaagaggca ggcgtaatct atctgatgga tggtgaaatt
     2461 aaatactcaa aaggagcatt tattcctaaa ggtgctgaaa ttcttggcgg ttgggctaag
     2521 gtgtaccgca aagaccgtac ttacccaacg gaaacagaag tatcttttga ggagtacgac
     2581 aattctaaaa tacgtgcaag agttaaggaa ctgacacaac aaggtaaaga tgttacttat
     2641 ccagtgatga actcatacgg taagccaata ggtgagaata actgggatac tatgccttgt
     2701 gtcatgatac gaaaagtagc tctagtgtca gcttaccgtg aggcgtttcc tgccgagctt
     2761 ggagcaagct atgaggctga cgaaattcag ctggataaca cacctaaaga cgtcactcct
     2821 caagaaagcc gtgaggatgt cgtagcacgc aagatggctc agattgagca attcaacaaa
     2881 gagcaagagg caaatcatgc agatcctgaa cctgctaaaa ctgaggagcc aatccagggc
     2941 gagttgctag acggtgaact tgaatattag gaggacaaca tgcaagaatt acaggttatt
     3001 gatgataaga aaatcaataa aatctatgag atgatcacaa cggatgaact tactagagag
     3061 tcttttgaaa aagacctcat agaggctact gagaagtaca aggactatat tcctacagct
     3121 ggaactctca aagacgacaa ggcaaagcgg gctgaattta acaagttaat tgagtctaaa
     3181 aatcgtatcc gcattgacac taaaaactta ctatcagaga cagctaacac atgggatagt
     3241 tatgctaagt caattattga cccatttgca accgtagtta gtgaatttga caaaggtatc
     3301 aaggaaatcg aagaacatca aagacaacta aaaatagata cggttaagag ttacctagcc
     3361 aacaaatcgg ctgagtacat gctggaccct cgtctctttg atgaaaaggc ccttgagtat
     3421 gtcaaggctg gcgatttcat ggcagacggc gtgacgctta aaaaagccac tatgaagtca
     3481 cttgatgaca tggtcacatt tgagtttcag aaacaacaag aatttgaaaa agccaagtca
     3541 gctatttcag ggttatgtgc tgagtacggc atgactgact caccttacat tagacagctg
     3601 aaagacttga ctcttgctga agcctttgaa caaatcaaag ctgattatga gtttgaaaaa
     3661 caaaaggaag aaatcagaca ggctcaagaa cgagcagagc gagaaagtca ggaactttta
     3721 gcagcccaac aaaccaaaca gcaagaacgg gctccaaaat caacgggaac cccaaatttt
     3781 gacccagagg caggcgaaat cttggacggt gagcaaatcc ctcaaaatga gcagaactct
     3841 cttagagggg ctgaaaatga cctaaaacga tatacccaaa aaatgacttt agaggtgtat
     3901 tttgtagaca cagccgaaaa agaccgtttc aaggctggtc taagtcaact cggatttgat
     3961 tttaaaaaga actatcaagt cagcggttat caacgtattg agccattgac tcaggctgaa
     4021 ctcaatgagc aatggggagg taaccatgga catcagaaaa atatctgaca gcgtagccat
     4081 ctactcggac ggcaagaaat tgcatgttat ccacaaccta ggggatgagt ttatcctaga
     4141 ttttaaggtg ggagaggata gcgtctggaa cctcaatggc caagtcgtag aaattattga
     4201 catgattgag cctgtcttta aagttttcag cttttgctca aaatctggag agggtatgca
     4261 acgcttaaaa catgctatcg tccactttga aatatttgag cagtacatca gagataatca
     4321 ggaagacctg atgatctggt ggcacaatcc aggaggggaa tatgattaaa accgtatttt
     4381 tttcatgtga ttatccacat catgaggcga ttgacgacca aataaatagc tggcttgccg
     4441 aaaatccagg cattaagttg attgacatca aatttcaatc aaatgtgtct gctgtcgctg
     4501 acagtggagt cagtgctgaa tattggcata catccgcatt gattatttac aaagttccct
     4561 cagagaacaa tataagcagt attaattcaa atggtttagg tttcataatc agctgtgaga
     4621 aatgtggtag cttatcaata atcaagggaa aagatgtagg tcaaaatgta tgttatgaat
     4681 gcaaaggaga gaaataatga atgattttat caaagagatt gggatggcta tcctatggat
     4741 gtttttaggg tatctcttgg gagagcgtag cactagaggg ggacaaatca gatgatcaat
     4801 aacgtcacac tggttgggag gcttgtagcg cctcctgatc tacgaaaaac gcctaacaat
     4861 gtatctagct tgcagggcac gcttgcagtc aatcgcaatt tcaaaaacga aaatggagag
     4921 cgtgaggctg attttatcaa ttttaaagct tggagaggta cagctgacat cattgctcag
     4981 tattgcagca agggctcact tattgggatc attgggcgct tacaagttag gtcttacgag
     5041 aaagacggtc agcgtcgata tgtgactgaa gtaatcgctg agagtgtagc tctgctagag
     5101 agtcgcaaca gtcagcacgg acaaggcaac agtttccaaa atgggaatag ctcacctttt
     5161 accgatccta acccctttga cctcccaaat gacggtttgc cgttttagga gggacagtta
     5221 gtggaaatag ataagattat aaaaaaagat gtcttggaat ttatggaaac aattcctgat
     5281 aataaaattg atttaatcgt aacagacccg ccttatttga taaattataa aacaaattgg
     5341 cggaaagaaa agcataaatt ttcaaatgtt atcaaaaatg ataacaatcc tgaattgata
     5401 aaagagtata taaaagagtg ttatcgaatt ttaaaagatg atacggctat ttatatattc
     5461 tgttcatttg acaaggttga tttttttaaa aaagaaattg aaaagtattt ttcagtaaaa
     5521 aatattatta tatggcgaaa aaataatcat accgctggcg atttagaggc gcagtttgga
     5581 aaacagtacg agatgattat attggcaaac aaaggacgga agaaattcaa cggtgagcga
     5641 ctgacagatg tttgggattt caagagagta agttcagata aactactcca tcaaaatcaa
     5701 aaacctattg aattgataaa acgatgtatt gttaaacatc ctgatgttgg ggatactgtt
     5761 tttgatggtt tcatgggaag cggtacgaca gcattagcag cgttagaaac ggataggcat
     5821 tttataggaa ctgaaataga tgaatattat tttggtatag cagaggagcg gataaaaaac
     5881 cacaacgctc aattaagttt atttgatgag gtatgagatg gagtggacgg attgggtgga
     5941 ttggaaacct gaaaccaaaa cggacattaa aaccaaaatt gaaaatgacg ggtacacttt
     6001 tccacactat gacaagaaaa acaacggcgt caagtacgtc atctctacac tggacatcaa
     6061 acgagactgt ctaagacttg gagtaccgtt tgaagatgtg taccctttgc aaacgacact
     6121 tttttaacag gagaaagaac atggcaagta aaatcaatgc gacagaacgt attgctatca
     6181 tcattgataa acaaaaaata gaggtcgtta cgactctaaa ctatgatatg agcattagct
     6241 ttgataacaa agacacggct cctacactag atgacaatgg tgaccttttt gaaccggtct
     6301 acaagtgcaa agttaaggca attcccaaaa atgatgtatt tttcacctca ttaacacgag
     6361 tcaagagcaa catcaagacg ctacaagagg ttaaaaaatt ctttgagttc gtaaacgaaa
     6421 acagagaaaa tctctttgag atggcaggat ttaagggggc tcttgaatga aattgaccct
     6481 gaacattgag cctaaacctc aatcacggcc aaggtttgca agacgtggga gttttaccac
     6541 aacttacgaa gacaaggata tgaaaacatg gcgcaatcat tgccagctgc tcattgctaa
     6601 tcagtacatg ggtcagccta tccttgaggg agctttgagg gcacggctta gattttatat
     6661 caaacctcct cagtacattt ctaaagtcaa gaagaaccaa caggccctcc tggatgaaat
     6721 tataccagta ggcaaaaagc ctgacataga taactacgaa aaagcgctat atgacagcat
     6781 gtcagggatc gtcttccagg acgacggtca gatagcgcta catgatgtag gcaagttcta
     6841 cagtctaaat ccacggatag aggttgagat tgaggtcatg aaatccctga gtatttgaag
     6901 aaatgaggag cagatggctg actacgcatt atatcaaggt gatgtgtttg ttacgcttgg
     6961 aacattagcg cagatcagta gcgagacagg aattactgaa aggatgttaa agtattacac
     7021 ttacacatca caccaaagac gacacccaaa cggtagggcc gttattaaaa ttgaggagga
     7081 agataatgag aattaagacg gaaagtgaag aagttggaag atgatggaag agttaaagca
     7141 aaaagttaat gaagtatata actggacggt agaagacggg aagccgcaac ctcccaagca
     7201 agatttacca caagcggtga aagaccgggc ggactatttt tgggaaatgg cagaagatgg
     7261 tatgacgttt atgggagcga tggaatgcat ctttgctgat gaaaagccta cagactatga
     7321 tttgggagct actaagggtt ggttgccaaa atctaaggag tttgatgatt ggattggcta
     7381 ttcgccaagc atggctcagg tagttattgc agtttatttg atttatggag gaaactaaga
     7441 tgaataagca ggaattgatt gagaaatata aaaaacttga gggtgtatgg aatgctgaag
     7501 gagcagaact agctcgtcaa atttttctgc aagacttgga acaactagat aaaccaaaac
     7561 cagtcaaagt tccgcagtgt gtggcggaat atatagaatt taaaaagaaa aacaattttc
     7621 atgtttacgg tgcaatgaga gtaattgaag atcattatga taagaaagtt cctgagtggt
     7681 tttacgaaaa taacatcgaa aaattctgtc ttgcttggct tgacggctac gaggttgaaa
     7741 aagagaagcg gtatttggtg actttaaaaa ataggcagcc tttggtcaaa tcgcaatcag
     7801 ggagtactct ttattttagt caagatataa cagctaggaa ttataaaggt actcaaaaag
     7861 aactagaaga cgcaaacttc ggctgggtgt ttgattgtcc agggattgag attgaggagg
     7921 tggagtgatg agccttacgc taaatagcac aattggagac ttagttttgg caatcggaga
     7981 aattatcgtt ggttctgatg gtaaaaccac tacagcgata ctggagatac ctgatcaaag
     8041 cttttactta gagattgagc ttaaattgaa ggaggaggtc ataaattgaa acgattcata
     8101 gctatctgga ttctgctatc tgctggattg aatatctggc agagtatcta cattaaaaag
     8161 ttagaagaaa agcgcccgat tgtcgtctat aaagctgata acgcaggcgc tgagatattc
     8221 ggtaaagtcg tcgagaaagg acggcatggc aagctatata cgcttaccat tcgtgactac
     8281 ggggtgttcg tggttacgaa ggacgtgtac gataaagtga aagttgggga tgaggtgtta
     8341 ctatgacaga aactattaaa ctaccagact attatgagcc tgattggaaa aatgcaaggt
     8401 acgggtcgtt ggaagagctt aaagaattgt tgctctttaa gcgtattgtg aaatgggata
     8461 aggacttttt gctgcttgaa gacggcacaa aggtcactat tgaaatgtct gaaagtgatt
     8521 gctgtgcctc agcaggtggg gagttccaag atgtatcact tgacgctgtg attactaata
     8581 ttgaaattgg agaaccggaa gaaatccccg accattgggg aactggttat aaaaacaaag
     8641 taactatctt ccataatcag aaccctgtag ctattgccaa ttgtgaagca gagcataacg
     8701 gctattatta cagcgtatgc tctttagtga ttggtgatat tcattttcca gttgttaatg
     8761 cttaggagga tttaacatga caccaagata tagagcgtgg ataaaaacag aaaaacgtat
     8821 g
//
LOCUS       DAVKMJ010000063         8704 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000063 DAVKMJ010000000
VERSION     DAVKMJ010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8704
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.063"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..624)
                     /locus_tag="VW348_001926"
     CDS             complement(<1..624)
                     /locus_tag="VW348_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEU9746780.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLA"
     gene            complement(912..1874)
                     /gene="nrdF"
                     /locus_tag="VW348_001927"
     CDS             complement(912..1874)
                     /gene="nrdF"
                     /locus_tag="VW348_001927"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEU9746781.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(2062..4221)
                     /gene="nrdE"
                     /locus_tag="VW348_001928"
     CDS             complement(2062..4221)
                     /gene="nrdE"
                     /locus_tag="VW348_001928"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEU9746782.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWTELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(4302..4520)
                     /gene="nrdH"
                     /locus_tag="VW348_001929"
     CDS             complement(4302..4520)
                     /gene="nrdH"
                     /locus_tag="VW348_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEU9746783.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPEKLKQLA"
     gene            4871..5134
                     /locus_tag="VW348_001930"
     CDS             4871..5134
                     /locus_tag="VW348_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEU9746784.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            5140..6873
                     /gene="ptsP"
                     /locus_tag="VW348_001931"
     CDS             5140..6873
                     /gene="ptsP"
                     /locus_tag="VW348_001931"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEU9746785.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            7128..>8704
                     /locus_tag="VW348_001932"
     CDS             7128..>8704
                     /locus_tag="VW348_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU9746786.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWLPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGNHYHF
                     IPYEQMSELEKRIARIIPLRYRSNHWVPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPS
                     NPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLG
                     AKKTDLPSSDREFYNKTYDLLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKL
                     VDDILAFLAPIRHPERLG"
BASE COUNT         2688 a         1642 c         1819 g         2555 t
ORIGIN      
        1 tgcgagtaaa tattttttat tagaattatt taaagcgatg cgttgagcct ctccctcttc
       61 ctcgctaaaa gtagctagag ctccgttttg aataccatta cagctaacga aagctttaga
      121 aaattggaga ttagagagat tttgtagggt caatgtgcca acaaaagcac ctgtaatatc
      181 gcgataattt ccacctatca aaatcaaatc tgttaatttt cgttcgctta aaatcagaaa
      241 aacaggtaga ctgttggtta cgacgcggat attgtcaata ggcaactcac gcgcaaaaaa
      301 ctctaatgtt gttcctggtc caatgaaaat agtttctctt tcttctacta gactgcctgc
      361 aaaatgggct atttcttgtt tttctgccgt ttggagggct tgtttttcaa tatttgatcg
      421 ctcattagtc aaaagggagt tggttcgaag tttttcagct ccaccatgca cacgaatcag
      481 caaatcttta tcagctaatt cctgtaaata gcgccttgca gtcatatctg aaacggctat
      541 ttcgtccata atctgtttaa ctgttatggt tcctttacta tttactatct ctaaaatttt
      601 ggttaatttt tcttgtttga gcatattatc acctcgtttc ctactactat cttaccataa
      661 acaaactcat cattcaaata caaaaacaac aaaatgaaac aaaaacaaaa atatcgaagt
      721 ttgttttcaa aactttcgat atttttgttg ggttattatt ttgttgtttc tagtttactt
      781 tttgatggtt aagagtggtg gagaattata ctcaatgaaa atcaaagagc aaactaggaa
      841 gctagccgca ggctgtactt gagtacggca aggcgaagct gacgtggttt gaatttgatt
      901 ttcgaagagt attagtccaa accgtagttg tagtcatcat cttgcatggc ttcaacttcg
      961 ccaagaaggt aaccatttcc gacttgagag aagaagtcat ggttggaagt tcctgttgaa
     1021 ataccgttca taacgattgg gttgacatct tcagctgaat ctgggaaaag tggatcttgt
     1081 cccatgttca tgagagcttt attggcattg tagcgaagga aggttttaac ctcttcagtc
     1141 caaccaacac cgtcataaag actctctgtg tagccttctt cattttcata aagagtatag
     1201 agtaggtcgt acatccattc tttgagtttt tcttgctctt cttcaggtaa ttcattgaaa
     1261 ccaagttgga atttgtaacc aatgtaggtt ccgtgaacag actcgtcacg aataatcaat
     1321 ttaatgattt ctgcaacgtt ggcaagtttg ttgttaccga gatagtagag gggagtgaag
     1381 aaaccagagt agaagaggaa ggtttcgagg aagacgctgg caactttctt ttcaagtggg
     1441 ctgccgttta ggtagatttc gttgacaatc tcagccttct tttgtaggta aggattggta
     1501 ttggtccatt cgaaaatttc ttcaatctca gccttagtat tcaaggtaga aaagattgat
     1561 gagtaagatt tagcgtggac agattccata aattggatgt tattgaaaac agcttcctca
     1621 tgtggtgtac ggatgtctgc gcgaagggct tgaaccccag tttcagattg catagtgtca
     1681 agaagggtta aaccaccaaa aacttttccg accaagtctt tctctttgtt agatagcttt
     1741 ctccagtcat ccaagtcgtt tgataaggga atacgtgtat cgagccaaaa ttgctccgtc
     1801 agtttttccc aagttgattt gtcgatgaca tcttcgatgg cattccagtt aatggctttg
     1861 tagtaagttt ccatttaaaa tctctttctg tgtttagtat tgcgaactca caattatttc
     1921 tactttacca taattctata ggagtatcgc acaaaaagtc ggaagcccga cttttaaaat
     1981 gttacataaa ttatgttatg acatagtaga tttgatttta tcagtgctgc ttagggaaaa
     2041 atagtgtttc tatgctagaa actaaatcac acagctttca cattggttgg cgccgacttc
     2101 tccaccgtca tctgtaaagg tacggacgta gtagatagac ttgattccct tgttaaaggc
     2161 atagttacga aggatggaca agtcacgtgt cgtttgttta ttttccctct tccattcgta
     2221 aaggcctttt ggaatgtcac tacgcatgaa gagggtgagt gaaagtcctt gatccacgtg
     2281 ttcagtcgca gcagcgtaaa catcgatgac tttacgcata tccatatcgt aggcagaagt
     2341 gtagtaagga atggtttctg tagacaagcc agcagcaggg tagtagattt taccaatttt
     2401 cttttcctga cgttcttcaa tacgttgcgt aatcgggtgg atagaagcag aaacatcgtt
     2461 gatgtagctg atagaaccat ttggcgctac agcaaggcga ttttggtggt aaagaccatc
     2521 ctcttgaacc ttgtcgcgaa gttcagtcca atcagcaaca ccagggataa aaacattttt
     2581 gaagagttct ttaacacggt ctgatgttgg aacaaattca ccagttacat acttgtcaaa
     2641 gtaacttccg ttagcatagt ctgatttttc aaagttgtgg aaggtaatac cacgttcacg
     2701 cgcaatattg tttgactcta ccaaggtcca gtagttcata agcataaagt agatgcttgt
     2761 aaattcaaca gactcaggtg aaccatattc aatgagttgt tgggcaaggt agctgtgcag
     2821 tcccatggca ccgagaccaa aggtgtgggc ttggctattt ccatggtcaa tcgttggtac
     2881 agctacgata tgtgaactat ctgtaacgaa agtaagggca cgaaccatag cacggataga
     2941 acgaccaaaa tcaggtgaag tcatcatgtt aaccacgttg gttgaaccca ggttacatga
     3001 aacatctgtt cccatttgaa ggaattcttg agcatcgttg atcaagcttg gttcttgaac
     3061 ttgaagaatc tcagaacaca agttactcat gataatcttt ccatcgacag gatttgcacg
     3121 gttagccgta tctatgttga ctacataagg atagccagac tcttgttgca atttagagat
     3181 ttcagtttcc aaatcccgcg ccttgatttt tgtcttgcga atatttggat ttgcgaccaa
     3241 ttcatcgtat ttttcagtaa tgtcgatgta attgaatggc acaccgtatt ctttttctac
     3301 agagtaaggg ctgaagaggt acatttcttc atttttacga gccaattcgt agaatttatc
     3361 aggtactaca acaccaagtg atagagtctt gacacgtact ttttcatcag cgttttcttt
     3421 cttagttgaa aggaaagcga tgatatctgg gtgaaagacg ttgaggtaga caacaccggc
     3481 accttgacgt tgccccaatt ggttggagta agagaagctg tcttcaaaaa gcttcataac
     3541 aggaacgaca cctgaagcag ctccttcata gcctttgata ggtgcaccag cttcacgaag
     3601 gttgctgagg gtaattccca caccaccacc aatacgtgaa agttgaagag ctgagttgat
     3661 agaacgtccg atagagttca tatcatccgt cacttggatt aggaaacaag ataccaactc
     3721 cccacgacga gcacgtccag cattcaagaa ggaaggagta gcaggttggt agcgttggtg
     3781 gatgatttca ttggcaatat cgattgcaac agcttcattc ccatcagcga aataaagggc
     3841 gttgaagaag acacggtctt ccatattttc aagatagtat tcaccgtcat tagtctttaa
     3901 ggcatattga ttgtaaaatt tataagctgc catgaatgac ttgaattgga agttttggtc
     3961 tttgataaat tgagccaatt cttccaagaa ctctggacgg tatttcttga taaaggctgt
     4021 ttcgatgtag ttgtgttcaa tgaggtaatt gattttgtct ttgattgaat caaaaaccat
     4081 agtgtttgga actacatttt ctttaaagaa agcatccaag gcttccttat ctttatgaag
     4141 catgatttgt ccattaacag gacggttaat ttcgttatta agacggaagt aagtcacgtc
     4201 ttcaagatgt tttaatccca taaaatttcc cttatctaat tacaaaagaa aggcttctaa
     4261 gttagcccta aaagcagttt cttctggatg atgtactaag attatgctaa ttgtttcagt
     4321 ttttctggtt ggaaacctga aaagacttca gttggtgttt ggataacagg agctgcgcta
     4381 aaaccgagct ctttaacttg atcgacgtac tcaggttgct catcaagatt gatttcacga
     4441 taagagacat tattactgtc caagaaacgc ttggtcattt tacattggac acaattgttt
     4501 ttagaataaa cggttaccat tgtgtaactc ctcttcaaaa tttaatacta tcttagtata
     4561 tcagaaaata aaattttgtc aatgatttaa actaaatata gtggtgttct tttgttgttt
     4621 ttatatataa acacaatata tagtgtttgt attgtgaaat agcaatgatt atcctataaa
     4681 ttgtttttga agaaactata tcctgtgttt tgttatctag gatagaagat tttcagcaag
     4741 ttatctgaaa ggaaattgaa ggaaaatcca gaaaatgctt gaaaaaaatc ctagaagatg
     4801 gtataatact aaattgtaag ggttatcaca tataactcaa aaaaagaaag aacaaaagga
     4861 gagtcaaact atggcttcta aagatttcca cgtagtggca gaaacaggta ttcacgcacg
     4921 tccagcaaca ttgttggtac aaactgctag caaatttgct tcagatatca ctcttgagta
     4981 caaaggtaaa tcagttaacc ttaaatcaat tatgggtgtt atgagtcttg gtgttggtca
     5041 aggtgctgac gtaactatct cagctgaagg tgcagatgca gatgacgcta tcgctgcaat
     5101 ctcagaaaca atggaaaaag aaggattggc ataagggaaa tgacagaaat gcttaaagga
     5161 atcgcagcat ctgacggtgt tgcagttgca aaagcatatc tactcgttca gccggatttg
     5221 tcatttgaga ctattacagt cgaagataca aacgcagaag aagctcgcct tgatgccgct
     5281 ctacaggcat cacaagacga gctttctgtt attcgcgaga aagcagtagg tacgctcggt
     5341 gaagaagcag ctcaagtttt tgatgctcac ttaatggttc ttgctgaccc agaaatgatc
     5401 agccaaatca aggaaactat ccgtgcgaag aaagtgaatg cagaagcagg tctgaaagaa
     5461 gttacagata tgtttatcac tatctttgaa ggcatggaag acaacccata catgcaagaa
     5521 cgcgcagcgg atatccgcga cgtgacaaaa cgtgtattgg caaaccttct tggtaaaaaa
     5581 ttgccaaacc cagcttctat caatgaagaa gtgattgtga ttgcgcatga cttgactcct
     5641 tcagatacag ctcaattgga caaaaacttt gtaaaagctt ttgtaaccaa cattggtgga
     5701 cgtacaagcc actcagctat catggcacgt acacttgaaa ttgctgctgt attaggtaca
     5761 aacaacatca ctgaaatcgt taaagacggt gacatccttg ctgttaacgg gatcactgga
     5821 gaagtgatta tcaacccgac agatgaacaa gcggcagaat ttaaagcagc tggtgaagcc
     5881 tatgcgaaac aaaaagctga atgggcactt ttgaaagatg ctcaaacagt gactgctgac
     5941 ggtaaacact tcgagttggc tgccaatatt ggtactccaa aagacgttga aggtgttaac
     6001 aacaacggtg cagaagctgt tggactttac cgtacagagt tcttgtacat ggattctcaa
     6061 gacttcccaa ctgaagatga gcagtatgaa gcatacaagg ctgttcttga aggaatgaac
     6121 ggtaaacctg ttgtcgttcg tacaatggat atcggtggag ataaggaact tccttacttc
     6181 gatatgcctc acgaaatgaa cccattcctt ggattccgtg ctcttcgtat ctctatctct
     6241 gagactggag atgctatgtt ccgcacacaa atccgtgctc ttcttcgtgc gtctgttcac
     6301 ggtcaattgc gtatcatgtt cccaatggtt gcgctcttga aagaattccg tgcagcgaaa
     6361 gcagtctttg atgaagaaaa agcaaacctt cttgctgaag gtgttgcagt tgcggataac
     6421 atccaagttg gtatcatgat cgagattcct gcagcggcta tgcttgcaga ccaatttgct
     6481 aaagaagttg acttcttttc aattggtaca aacgacttga tccaatatac aatggcagca
     6541 gaccgtatga acgaacaagt ttcatacctt taccaaccat acaacccatc aatcctacgc
     6601 ttgattaaca atgtgatcaa agcagctcac gctgaaggta aatgggctgg tatgtgtggt
     6661 gagatggctg gtgaccaaca agctgttcca cttcttgtcg gaatgggctt ggatgagttc
     6721 tctatgtcag caacatctgt acttcgtaca cgcagcttga tgaagaaact cgacacagct
     6781 aagatggaag agtacgcaaa ccgtgccctt acagaatgct caacaatgga agaagttctt
     6841 gaacttcaaa aagaatacgt taattttgat taatcgaaaa gtccctgcaa ctcagttaca
     6901 gggacttttt ttgatatttt aaaaagaatt ttcaagaaaa tctttcttat aaaaagtcca
     6961 accttgaaaa agtagtggtc agaacaaaaa atacttaaat ggttcataaa attcttgaca
     7021 agttggagat ttaggagtaa actattaacc agttaagtaa tagagaggag tttctgcaat
     7081 ttagaaatga attgcaacta gaaatatcaa atagaaagag agtttcgatg aaaattaata
     7141 agaaatacct tgttggttct gcggcagctt tgattttaag tgtttgttct tacgagttgg
     7201 gactgtatca agctagaacg gttaaggaaa ataatcgtgt ttcctatata gatggaaaac
     7261 aagcgacgca aaaaacggag aatttgactc ctgatgaggt tagcaagcgt gaaggaatca
     7321 atgctgagca aatcgtcatc aagataacag accaaggcta tgtcacttca catggcgacc
     7381 actatcatta ttacaatggt aaggttcctt atgatgcgat tttcagtgaa gaattactca
     7441 tgaaagatcc aaactataag ctaaaagatg aggatattgt taatgaggtc aagggtggat
     7501 atgttatcaa ggtagatgga aaatactatg tttaccttaa ggatgctgcc cacgcggata
     7561 acgtccgtac aaaagaggaa atcaatcgac aaaaacaaga acatagtcaa catcgtgaag
     7621 gtgggactcc aagaaacgat ggtgctgttg ccttggcacg ttcgcaagga cgctatacta
     7681 cagatgatgg ttatatcttt aatgcttctg atatcataga ggatactggt gatgcttata
     7741 tcgttcctca tggagatcat taccattaca ttcctaagaa tgagttatca gctagcgagt
     7801 tagctgctgc agaagccttc ctatctggtc ggggaaatct gtcaaattca agaacctatc
     7861 gccgacaaaa tagcgataac acttcaagaa caaactggct accttctgta agcaatccag
     7921 gaactacaaa tactaacaca agcaacaaca gcaacactaa cagtcaagca agtcaaagta
     7981 atgacattga tagtctcttg aaacagctct acaaactgcc tttgagtcaa cgccatgtag
     8041 aatctgatgg ccttgttttc gacccagcgc aaatcacaag tcgaaccgcc agaggtgtag
     8101 ctgtccctca tggtaaccat taccacttta tcccttatga acaaatgtct gaattggaaa
     8161 aacgaattgc tcgtattatt ccccttcgtt atcgttcaaa ccattgggta ccagattcaa
     8221 gaccagaaca accaagtcca caatcgactc cggaacctag tccaagtctg caacctgcac
     8281 caaatcctca accagctcca agcaatccaa ttgatgagaa attggtcaaa gaagctgttc
     8341 gaaaagtagg cgatggttat gtctttgagg agaatggagt ttctcgttat atcccagcca
     8401 aggatctttc agcagaaaca gcagcaggca ttgatagcaa actggccaag caggaaagtt
     8461 tatcgcataa gctaggagct aagaaaactg acctcccatc tagtgataga gaattttaca
     8521 ataagactta tgacttacta gcaagaattc accaagattt acttgataat aaaggtcgac
     8581 aagttgattt tgaggctttg gataacctgt tggaacgact caaggatgtc tcaagtgata
     8641 aagtcaagtt agtggatgat attcttgcct tcttagctcc gattcgtcat ccagaacgtt
     8701 tagg
//
LOCUS       DAVKMJ010000064         8427 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000064 DAVKMJ010000000
VERSION     DAVKMJ010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8427
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.064"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..241
                     /locus_tag="VW348_001933"
     CDS             <1..241
                     /locus_tag="VW348_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phosphate uptake regulator PhoU"
                     /protein_id="HEU9746787.1"
                     /translation="CYREEQSGCLDMVVIQKQNEIEELSINMEKKIMNYIFEDDGNVS
                     EVISALDIIHHLDKIAHTTQAIYKWIMYRKYGNIN"
     gene            254..1729
                     /gene="galT"
                     /locus_tag="VW348_001934"
     CDS             254..1729
                     /gene="galT"
                     /locus_tag="VW348_001934"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEU9746788.1"
                     /translation="MKTIIDNFVDRVIEYGMYNEIDKIYVKNRVLALIGEEGIDRISD
                     ENDLKQIKDYLVEIALKNGKIKDLIEEKECLGAELMNFIVPLPSRLNDIFWSSYDISP
                     QEAVEEFYKLSKDSDYIKTSAIAKNIEFRASTKYGELEITINLSKPEKDPKTIAAEKL
                     VKATNYPKCLLCMENEGYQGRINYPARSNHRIIRLKLGDEVWGFQYSPYSYFNEHAIF
                     LNSQHVPMAITSKTFEQLLEIVDILPGYFAGSNSDLPISGGSILSHNHYQGGKHIFPM
                     EKAKFESEFCFKDFEDVNAGIVKWPMSVIRLQSENKNRLLDLATKILNKWREYSDLEV
                     DIIAMTEDVPHHTVTPIARKVDGRYELDIVLRDNHTTEQYPDGVFHPHQDVQHIKKEN
                     IGLIEVMGLAILPPRLKPELEEVGKYLLGEDNAIADYHLEWADQLKEKYPRINKEEVN
                     SVVQHEAGQVFARVLEDAGVYKNTPSGHEAFMRFVKSVGIN"
     gene            1742..2752
                     /gene="galE"
                     /locus_tag="VW348_001935"
     CDS             1742..2752
                     /gene="galE"
                     /locus_tag="VW348_001935"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEU9746789.1"
                     /translation="MAILVTGGAGYIGSHTVVELLNLGKEVIIVDNLSNSSKLVLDRI
                     EAITGIRPVFYELDVCDKQALRKVFEQESIDAAIHFAGYKAVGESVQKPVMYYKNNIM
                     STLALVEVMSEFNVKKIVFSSSATVYGINNQSPLIETMQTSATNPYGYTKVMLEQILK
                     DVHVADSEWSIALLRYFNPIGAHESGLIGEDPSGIPNNLMPYIAQVAVGKLSELSVFG
                     NDYDTLDGTGVRDYIHVVDLAIGHIKALEKVSEKTDVYIYNLGSGEGTSVLQLVNIFE
                     SVNKIPIPYKIVPRRSGDVATYYANADKAYKELNWRTTKSIEDMCRDTWNWQSKNPNG
                     YN"
     gene            2916..3575
                     /locus_tag="VW348_001936"
     CDS             2916..3575
                     /locus_tag="VW348_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEU9746790.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            3600..4667
                     /locus_tag="VW348_001937"
     CDS             3600..4667
                     /locus_tag="VW348_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEU9746791.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            4771..5781
                     /locus_tag="VW348_001938"
     CDS             4771..5781
                     /locus_tag="VW348_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9746792.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            5793..7484
                     /locus_tag="VW348_001939"
     CDS             5793..7484
                     /locus_tag="VW348_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU9746793.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            7487..8197
                     /locus_tag="VW348_001940"
     CDS             7487..8197
                     /locus_tag="VW348_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEU9746794.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT         2855 a         1155 c         1657 g         2760 t
ORIGIN      
        1 ttgttataga gaggaacaat ctggatgttt agatatggtt gttatacaaa aacagaatga
       61 gatagaagag cttagtataa atatggaaaa gaaaataatg aattacatat ttgaagatga
      121 tgggaacgtt tctgaagtaa ttagtgcttt agatattatt catcaccttg ataaaattgc
      181 tcatactacg caagcaattt ataaatggat aatgtataga aaatatggga acataaatta
      241 gaaagaaaaa tatatgaaaa caattattga taattttgtt gatagagtaa ttgaatacgg
      301 aatgtataat gaaattgaca aaatatatgt gaaaaataga gtactagcgt taataggtga
      361 ggagggaatt gatcgcattt ccgatgaaaa tgacctgaaa caaataaaag attacttagt
      421 ggaaatcgcc ttaaaaaacg gtaaaattaa agatttaatc gaggaaaagg aatgtttagg
      481 agcagagtta atgaatttca tagttccttt acctagtcga ttaaatgata ttttttggag
      541 ttcatatgat atatcacctc aagaagcagt tgaagagttt tataagttaa gtaaagatag
      601 tgattatatt aaaacttctg ctattgctaa gaatattgag tttcgagcat caactaaata
      661 cggagagcta gagattacga taaatttgtc aaaacccgaa aaagatccaa aaacaattgc
      721 tgctgaaaaa ttagtaaaag caactaatta tcccaaatgt ttactatgta tggaaaatga
      781 aggatatcag gggcgaataa attatccagc acgttcgaat catagaatta ttcggttgaa
      841 acttggtgac gaagtatggg gattccagta ttctccctac tcatacttta atgagcatgc
      901 gatatttttg aatagtcaac atgtaccaat ggctattacc tctaaaacat ttgaacaatt
      961 attggagatt gttgatattt tgccaggata ttttgctggt tcaaattctg atcttcctat
     1021 ctcaggaggc tccattctta gtcataacca ctaccaggga gggaaacata ttttcccaat
     1081 ggaaaaagca aaatttgaga gtgaattttg ttttaaagac tttgaggatg ttaatgctgg
     1141 tattgtaaaa tggccaatgt cagtaattag gttacaaagt gaaaataaaa atcgcttgtt
     1201 agatttagct actaaaattc taaataagtg gagagaatat tcagatttag aagtagacat
     1261 cattgctatg actgaagatg tcccacacca tacggtgact cctattgctc gtaaagtgga
     1321 cgggagatac gaattagata ttgttctaag agataatcat actactgaac aatacccaga
     1381 tggtgttttc catcctcatc aagatgtaca acatattaaa aaggaaaata tcgggttaat
     1441 cgaagtgatg ggacttgcga tattaccacc tcgtttgaaa ccagagttag aagaagttgg
     1501 aaaatatctt ttaggagagg ataatgcaat tgcggattat catttagaat gggccgacca
     1561 attgaaagaa aaatatcctc gcattaataa agaagaggtt aatagcgtag ttcaacacga
     1621 agcaggacaa gtgtttgcga gagttctgga agatgcagga gtttataaga atacaccgtc
     1681 tgggcatgaa gcgtttatga gatttgttaa gtcggttgga attaattagg aggaaaccca
     1741 gatggcaata ttggtaacag gcggagctgg ttatattggt agccataccg tagtagaatt
     1801 actaaattta ggaaaggaag ttatcattgt cgacaacctt tcgaactcta gcaaattggt
     1861 gctagaccgt attgaagcaa ttacaggaat acgtcccgtg ttttacgaat tagatgtttg
     1921 tgataaacaa gcattgagaa aggtatttga acaagaatcg attgatgctg caattcattt
     1981 tgcaggttat aaagctgtcg gagaatccgt gcaaaagcct gtgatgtact acaaaaataa
     2041 tattatgagt acattggcac ttgttgaagt gatgtcagaa tttaatgtta aaaagattgt
     2101 cttttcttca agtgcgactg tatatggaat taacaatcag tcacctctaa ttgagacgat
     2161 gcaaacaagt gcgacaaatc cttatgggta tacgaaagtg atgcttgagc aaattttaaa
     2221 agatgttcat gtggcagatt cagaatggag tattgcgttg cttcgttatt tcaatccaat
     2281 tggtgctcat gagtctggtt tgattgggga agatccctca ggaattccta acaacttgat
     2341 gccttatatt gcacaagtag cggtaggtaa gctatcagag ctaagtgtgt tcggaaatga
     2401 ttatgatacg cttgatggta ctggtgtgcg tgattatatc catgtagtag atttagcaat
     2461 aggacatata aaagctttag aaaaagtatc tgaaaaaaca gatgtttata tctataacct
     2521 aggctcggga gaaggcacta gtgtattaca acttgtaaat atatttgaaa gtgttaataa
     2581 gatccctatt ccttataaaa tagttccaag acgttcagga gacgttgcaa cttattatgc
     2641 aaatgcagac aaagcatata aggaattaaa ttggaggaca acaaaatcga ttgaagacat
     2701 gtgtagagat acatggaatt ggcaatcaaa aaatcccaat ggctataatt gatgatactg
     2761 tctatatgag tgctgtattt tggaaaaatt acttaacctt ttaatgaaag ataaattaaa
     2821 aaaaatgttt gacagcgctt gacaaaggaa acggtttcat tgtataatgt aaacacaatg
     2881 acaccgatgt caaatataaa aaagaaggtc tttatatgaa aaacttaaca aaaattaagt
     2941 tcaaagaaaa tggggaattt aatcatttcc ctgggaatac agttgtagca aatctttata
     3001 ctaaacaaga tttgatggaa gttgttgata ttattcaatc acgttataga gaattaccat
     3061 ttatcgataa gtttacttta actccaagga attctattca catgactgta attgaattgt
     3121 tgtgccatga aaatcgtgaa acggagtttt ggagcagtaa tcttcctcta gatacacctt
     3181 tacaggaaat acatgattac tttgctaaac aacttgaaat ttttccattg ttggatgaag
     3241 aaattcatat gcgtataact gaaatgggaa aacaaaacat actagttgaa cctgcagatg
     3301 aagcttctgc aaagagatta gaagaaattc gtacttatgt ctcagaaaaa gcaggtgttt
     3361 gtttccctaa tcatgataga tatcaattcc atatttcaat tgggtatctt cggattcctc
     3421 taaccgaaga ggaggaagaa gagtttacta aagtcagagc agaattaact gaaattttat
     3481 tagagaagat tccaactatt actgtaaacc gtattgacta tactgtattt gaagatatga
     3541 gacaatttgt tccatatcac gaaaaattta aataaaataa taaaaaagga gaacttatca
     3601 tgaaaaaaat gaaagtttgg tctactgtac ttgcaacggg agttgctctt actacacttg
     3661 ctgcttgctc tggaggttca aattctacga ctgcttcttc atctgaagaa aaagctgata
     3721 aaagtcaaga attagttatc tattcgaact cagtctcaaa tggtcgtggt gattggttaa
     3781 ctgctaaagc aaaagaagct ggttttaata taaaaatggt tgatatcgct ggcgctcaat
     3841 tagcagaccg tgttattgct gagaagaata atgcagttgc agatatggta tttggaattg
     3901 gtgctgttga ctcaaataaa attagagatc aaaaattact agtacagtac aagcctaaat
     3961 ggttagataa aattgatcaa tctttatcag ataaagataa ttattataat cctgtgattg
     4021 ttcaaccatt agttttaatt ggggcgcctg atgtaaaaga aatgcctaaa gattggactg
     4081 aattaggtag taagtataaa ggtaaatatt caatttatgg tcttcaaggt ggtacaggac
     4141 gggcaattct agcaagtatc ttagttcgtt acctggatga aaaaggagat ttaggcgtat
     4201 cagaaaaagg atgggaagtt gcaaaagaat actttgcaaa tgcctatact cttcaaaaag
     4261 gtgaaagctc agttgttaaa gcgttagata aagaaagccc aattcaatac ggtatgatct
     4321 ggggttctgg agcgttaatc ggacaaaaag aacaaaatgt tgaattcaaa gttatgactc
     4381 ctgagattgg tgtaccattt gtaactgaac aaactatggt tttaagcact agtaaaaaac
     4441 aagcgttagc taaagaattt attgattggt ttggtcaatc agaaattcaa gtagaatata
     4501 gtaaaaaatt tggatctatt cctgcaaata aagatgccct aaaagagtta cctgaagata
     4561 cgaaaaaatt tgttgatcaa gtgaaaccac aaaatattga ctgggaagct gttggaaagc
     4621 atttggatga atgggtagaa aaagctgaat tagaatacgt aaaataagaa ataagagtta
     4681 ttttttatgt ccaagtctct ctattatttc taaatttaag gaagaaataa agagaggctt
     4741 ttggttttag taatagaggg agttagtgag atgattaaat ttgataatat tcaaattaaa
     4801 tatggtgatt ttgttgcaat tgataatctg aatttagata tacatgaagg ggaattcttt
     4861 acatttcttg ggccttcagg atgtggtaaa tcaactactt tgagagcatt ggtaggtttt
     4921 ttagatccat catcaggaag tattgaagtt aatggaacag atgtcactca tttggaacct
     4981 gaaaagcgtg ggattggtat tgtatttcaa tcttatgcgc tatttccaac tatgactgtt
     5041 tttgataata ttgcatttgg tttaaaagtt aagaaggtag ctccagatgt tattaaagct
     5101 aaagtatcag cagtggcagc aaaaattaag atctctgatc aacagttaca gcgtaatgta
     5161 tcagaattat ctgggggtca acaacaaagg gtagcattgg ctcgtgctct ggttcttgaa
     5221 cctaaaattc tttgtctaga tgaaccattg tcaaaccttg acgcaaaatt acgtgtagat
     5281 ttgagaaaag agttgaaaag acttcaaaaa gagttaggta ttactacttt atatgttact
     5341 catgatcaag aggaagcctt gactttatct gatagaattg cagtctttaa caatggatac
     5401 atcgaacagg tcggtacacc agtagagatt tatcataatt ctcaaactga atttgtatgt
     5461 gattttattg gagatattaa tgttttgacc gatgaaacag tccacgaagt attattgaaa
     5521 aatacaagcg ttttcttaga ggataaaaaa ggatacattc gattagagaa agttcgattc
     5581 aatcgtgaaa ctgaacaaga ttttattcta aaagggacaa ttattgatgt tgagttttct
     5641 ggagttacaa ttcactatac aataaaagtt tctgaaagtc agattcttaa tgtaacaagt
     5701 attgatagtc aggctgctat tagatctgtc ggagaaagtg tggaattatt tatcacacca
     5761 tcagacgttc tgcaatttta aggaggtgca gtatgcgtca taaattaaat ttaaaagatt
     5821 ggcttattcg tttagggtta atctggttct tagtaacatt tattatttat ccaaactttg
     5881 atctagtagt gaatgtattt gtaaaaggag gagaattttc ccttgatgct gtacatcgtg
     5941 ttctaaaatc tcagagggca cttcagagta ttatgaacag ttttaagtta gcattttcac
     6001 tcattattac agttaatgtc gtaggtattc tttgtgttct atttacagag tactttgata
     6061 ttaaaggtgc taaaatttta aaattaggtt atatgacctc tttaatttat ggaggagtgg
     6121 ttttagcgac tggatataaa tttgtctatg gtccttatgg attgattaca aaatttttac
     6181 aaaatgttat cccttcttta gactctaact ggtttattgg gtatggtgca gtcttattca
     6241 ttatgacatt ttcaggaact gctaatcata cattgttttt aacaaataca attcgaagcg
     6301 ttgactatca cactattgag gctgctcgaa atatgggagc aaaaccattt actgttttcc
     6361 gaaaagtagt gttaccaacc ttaattccaa ctctatttgc acttactatt atggtttttc
     6421 ttagtggttt atctgcagta gcagcaccca tgattgttgg tggtaaagaa tttcaaacta
     6481 taaatccaat gattattaca tttgcaggga tggggaattc tcgtgattta gctgccttac
     6541 ttgcaattat tttaggtatt gcaactacaa ttttgcttac tatcatgaat aagatagaaa
     6601 aaggtggaaa ttatatttct atctctaaga ctaaagcgcc tcttaaaaaa caaaaaattg
     6661 cgtctaagcc ttggaatatc attgctcaca ttgtagcata tggattgttc acagttttca
     6721 tgcttccact aatttttata gtattatact catttacaga tccagttgca attcaaacag
     6781 gtaacttaac attatcaaac tttactttag aaaattatcg cttattcttt agtaatagtg
     6841 cggcattctc tccattcttg gtcagcttta tttattctat tattgctgcg acaacagcaa
     6901 caattctcgc agttgtattt gctcgtgttg tcagaaaaca taaatctcgt tttgatttct
     6961 tatttgaata tggtgctcta cttccttggt tactaccaag tacactttta gcagtaagtt
     7021 tattatttac ttttaatcag ccacaatttc ttgttttgaa tcagattttg gtaggtagtt
     7081 tggtaattct acttattgca tatatagttg taaaaatccc attttcttat agaatggtac
     7141 gtgctatttt atttagtgtt gatgatgaga tggaagatgc agcaagaagt atgggtgctt
     7201 caccttttta tactatgatg aaggttatca ttccatttat tttaccggtt gttctctctg
     7261 ttattgcttt aaactttaac tctttattaa ctgacttcga cttatctgta ttcctttacc
     7321 atcccctagc tcaaccatta ggtattacga ttcgatctgc aggtgatgaa acagcaacat
     7381 ctaatgcaca agctctggta tttgtttata caattgttct gatgattatt tctggaacgg
     7441 tattatactt cacacaaaga ccggggcgta aagtaaggaa ataatcatga cagccactag
     7501 tcttgggtta tcaaatattg aaatagttgt caggattgtt ttatcagtag tcattggtag
     7561 tataattggt ttagagagag ggagcaaatc ccagcctgca ggcatccgaa cttatagtat
     7621 tgtttgtcta gctgcatgtt tgattatgat gacgaatgaa tacgtatctt ataaatttgg
     7681 gacaggagat cctacacgat taggagctca agttatatca ggtgtgggtt ttctaggcgc
     7741 tggaacgatt cttattacag ataagaagaa aattacaggt ctgacaactg cagcaggcat
     7801 ttgggcttcg gcaggaattg gattagctat tggagtaggt ttttatgagg gagctctttt
     7861 agtagccatt tctgtttggg gtgtgatatc catgttccaa ccactaaaaa aatatctgca
     7921 aaatcgttct aaaatgattg aattgtatat agtagttaaa tctacagaag cctataatcg
     7981 tgtattggtt tattgtgcag aaaatggtat cagaatgacc gattcaagaa cagcgtttgg
     8041 agatgttaat tctgacagaa ttgaatactt tgatgttccg gacaaaaaaa tagcgtcatt
     8101 tattactctg gaattatcag gtagatttga acatcttcga ctgatggaag aaattgctaa
     8161 tattgtaggt gttatttatg tcgaagaaat tagctgaaat ttagtaaaca aagggacaga
     8221 tgtttttgtc cttttgtttt ttagatgttt taatcatcta atttttgagt agatttttgc
     8281 tcagaggttt ttatgaaaga ttataaaatc aattttgatt taggtaaaat agaatatttt
     8341 gataataatt gtttgataca agtatacaaa tttatttctt tttatgatat ttgtgaaatg
     8401 gtgtttgcct ttcatttacc tcctgat
//
LOCUS       DAVKMJ010000065         8322 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000065 DAVKMJ010000000
VERSION     DAVKMJ010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8322
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.065"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(262..429)
                     /locus_tag="VW348_001941"
     CDS             complement(262..429)
                     /locus_tag="VW348_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746795.1"
                     /translation="MSLIYSSAKKDFLYWNVLIFIMELPNDVKVQFYELRKKVQSFNQ
                     LSKRFGMDVSG"
     gene            complement(596..667)
                     /locus_tag="VW348_001942"
     tRNA            complement(596..667)
                     /locus_tag="VW348_001942"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(632..634),aa:Arg,seq:cct)
     gene            complement(709..1056)
                     /gene="rplS"
                     /locus_tag="VW348_001943"
     CDS             complement(709..1056)
                     /gene="rplS"
                     /locus_tag="VW348_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEU9746796.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(1175..1504)
                     /gene="crcB"
                     /locus_tag="VW348_001944"
     CDS             complement(1175..1504)
                     /gene="crcB"
                     /locus_tag="VW348_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU9746797.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(1498..1872)
                     /gene="crcB"
                     /locus_tag="VW348_001945"
     CDS             complement(1498..1872)
                     /gene="crcB"
                     /locus_tag="VW348_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEU9746798.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLV
                     LYLLLSIGGGLLLAYFLGRKKW"
     gene            complement(1869..2135)
                     /locus_tag="VW348_001946"
     CDS             complement(1869..2135)
                     /locus_tag="VW348_001946"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEU9746799.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(2251..2694)
                     /locus_tag="VW348_001947"
     CDS             complement(2251..2694)
                     /locus_tag="VW348_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEU9746800.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSIGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVV"
     gene            2798..3733
                     /locus_tag="VW348_001948"
     CDS             2798..3733
                     /locus_tag="VW348_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEU9746801.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            3787..4071
                     /locus_tag="VW348_001949"
     CDS             3787..4071
                     /locus_tag="VW348_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEU9746802.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(4128..4346)
                     /locus_tag="VW348_001950"
     CDS             complement(4128..4346)
                     /locus_tag="VW348_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746803.1"
                     /translation="MSISPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETKPTDESGT"
     gene            complement(4343..5373)
                     /locus_tag="VW348_001951"
                     /pseudo
     CDS             complement(4343..5373)
                     /locus_tag="VW348_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            5715..7061
                     /gene="gdhA"
                     /locus_tag="VW348_001952"
     CDS             5715..7061
                     /gene="gdhA"
                     /locus_tag="VW348_001952"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEU9746804.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVISFRVPWVDRDGKVQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGSVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSNLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGVV"
     gene            complement(7350..>8322)
                     /locus_tag="VW348_001953"
     CDS             complement(7350..>8322)
                     /locus_tag="VW348_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746805.1"
                     /translation="VNMNPISFLENIEESSMQSVIVSSPESEKYEWQLAYLTQLENVK
                     NEDLQTLKSILEANSLPCYFTILNFERLILKDPSLKELLIQKAGNTNFVISDFIREEE
                     VPKLINLIGVKELKFWYLINLENCQNHSYNLFQKLGEKDVDFSVEVLKKIDELRIGHS
                     NLGYMVLHSISEFRDKKEIYKKFIRFAINRPYYYYNNMIDDIIKNDSQIILEILEETN
                     NEQSAIRLVNLGVEFLENNNQKLILFNLLRAKGFGKKSFQEIHFTPYSHFYTDSHVPV
                     LELEKELLERIKKIFETGIDYINLLLYLNKLIDCKRKAIERELEKEF"
BASE COUNT         2615 a         1664 c         1417 g         2626 t
ORIGIN      
        1 cagaaattta agctagatct aacaatttaa ttgttaaatg atattgttta gagatataat
       61 tcctaaaaaa ttagacaaat aatttatcca taagatttgg ttctgcatta cactgaacta
      121 aatcttttta tttttaatac atttgttatt atataggctt ttgttgattt atttcttgtt
      181 ttaattcagt ggaatagtaa cgattcttcc cttttttaac gctctctgtt caataacgat
      241 caattcacct tgtcacatac cttagccaga aacatccata ccaaatcttt ttgaaagctg
      301 attaaagctt tgtactttct ttctaagttc atagaactga accttaacgt catttggcaa
      361 ttccataata aaaataagga cattccaata aaggaagtcc tttttagcac tactataaat
      421 caaagacatt tttatgatcc attttattct ataatcattg accaaaatat aatttttggt
      481 caaaatttgg tcaaaaaaat taaaaatgct aaattatttt taaaaatgaa cttgagaaaa
      541 ttgccttcaa ataaacattt tgaattttct ttgtctttct ttacattact aaaaatgccc
      601 cctgcaggaa tcgaacctgc aactactcct taggagggag ttgttatatc cattgaacta
      661 agggagctag ataaaaactc tgctgaaaag cagagttttt tagtcgaatt aacgacggat
      721 ttctttgata cgagctgctt taccttgaag agcacgcaag tagtacaatt tcgcacgacg
      781 tactttaccg taacgaacaa cttcgatttt ttcaacacgt ggagtgtgga ttgggaagat
      841 acgctcaaca cctacaccgt tagagatttt acgaactgtg tagttttctg agattccagc
      901 acctttacgt gcgataacaa caccttcaaa aatctggata cgttcacggt taccttcgac
      961 aactttcgcg tgtacacgaa cagtgtcacc aggacggaat gatgggatat ctgtacgaag
     1021 ttgaccttca gtcaagcttt ggattaatgg attcatttta ttctcctatc tttgtcaatc
     1081 ttgaggaaat ttcctcagcg gataaactgt atttttgtgc gtccatcaca cacaagatac
     1141 agtctaccaa attttcacaa aaaagtaaag aaatttatag caaaattcct aaaaaaatcg
     1201 caaccaaacc acctatgtaa gtcaaagtca ggtaagaata aaagaccttc ttatcactta
     1261 acagtctttg aagttcgtca ttcaaggtcg aaaaagttgt taaaccgcca caaaatcctg
     1321 ttgctagaat agcatatact tccttagact ctacatgatt gtagaatact ccaattaaaa
     1381 aacaacctaa aagattagct atgagcgttc cgagtggcaa tttagaagct tgattgtagc
     1441 gggaaaagaa ataccgtacg agtgctccca agccacaggc gattgcaaga tagacgatta
     1501 ccatttcttc ctccctagaa aataagctaa gagtaggcct ccaccgatgc tcaaaagcaa
     1561 atacaggact aaactaagat aacgccctgt atcaagcagc ttcacagtat caagcattag
     1621 gctggaaaaa gttgttaaac ctccgcaaaa acccgtcccc agtgctaaaa tcaagccctt
     1681 actagtcccc ttatagacca gatagccctt gacaagaaaa atcaagcaga aaattcccag
     1741 atagttgaca aagagagtgc cccaaggaaa gtctggactg gctggtaacc aggtggaaac
     1801 tagatatcgg acaagtccgc ccaacatagc agctagaaaa attcctagcg gataaaattg
     1861 ttcttttttc atttgatatt ttgatcctga taatcacgcg aacgtttgag tatgtccgaa
     1921 aaagtcgcta caatagtctc ctgatagcgc ttgtcctcta cacgactcct aaccttttca
     1981 aaaataactt cttctctctt agtatctaaa atcggtttac ctgaagcttt cttataagca
     2041 accaccccct caactaaatg cattcgttct tctaacagtt tgacaatttg gtcatcgatt
     2101 tgatcgattt cttgacgaat aatatctaaa tccatacagt ctcctccttt atttgaatta
     2161 ttgtatcaaa aagccatcaa ttaggctagt aaaatcccaa ctctcgataa gaaaaatgca
     2221 ctgattgatt acatcagcgc acttttatgc ttatactact ttagcaacca attcttctgc
     2281 gaattgttcc aagcgttcaa tatcttcttc ctcggcagaa agatcaactt taacacactc
     2341 tgaacctttt tctgctccta ttgacacaaa gacacggtca aagtcatcaa cagccttaca
     2401 gaattcatcg tagaaggtat ctcctgagcc gaccactccg tagattttgc cattcaagtt
     2461 gagatctgct aggtcttcgt agaagtccat catctcatct ggcaattcac catcaccata
     2521 agtataggtc gcaacgatag cgatgtctgc ttccaagaag tctgaagcgt caacagttgt
     2581 acattcatca acatcaacat ccaagcccaa gtcacgtaat ttgtctgcta caatatctgc
     2641 aatttcttcg gtattaccgg tcatactggc aaatacaatt tttgctaatg ccatatcgtc
     2701 ctcctcaatt tatctttctc cattatatca catctttttc attttaaaaa taaaaattct
     2761 tgtgctacaa tgaaatgaga aagaattgag gttatttatg gagatttgcc aacaaatttt
     2821 agaaaaaatt aaagaatacg acaccattat cattcatcgt catatgaaac cagaccctga
     2881 tgccttggga agtcaggtgg gattgaaagc cttgctggaa catcatttcc cagaaaaaac
     2941 catcaaagcc gtcggttttg atgaaccaac tcttacttgg atggctgaga tggatcttgt
     3001 tgaagataga gcctaccaag gcgcacttgt catcgtctgt gatacagcta atactgctcg
     3061 tatcgatgat aagcgctata gtcaaggtga ttttctcatt aagattgacc accatccaaa
     3121 tgatgatgta tacggtgacc tgtcttgggt cgatactagt tcaagtagcg ctagcgagat
     3181 gattacccta tttgcccaaa caacccaact agccttggca gatcgcgatg ctgagttgct
     3241 ctttgcagga attgtcggtg atacaggtcg cttcctctac ccttctacca ctgcacggac
     3301 tcttcgcctg gctgcttatt tgagagaaca taactttgac tttgcggctc tcactcgcaa
     3361 aatggacact atgagctaca aaattgctaa actgcaaggc tacatctacg accatctgga
     3421 agtggatgaa aatggtgctg ctcgcgttat cctgagtcaa gaagtcttga aacaatacaa
     3481 tgtaaccgat gctgaaactg cagccattgt cggtgcacct ggacgcattg acagagtgag
     3541 tctctgggga atttttgtcg aacaggctga tggccactac cgagttcgct tacgcagtaa
     3601 aatccatcct atcaatgaaa tcgccaagga gcatgatggt ggaggccacc ctctagcaag
     3661 tggtgctaat tcctatagcc tagaagaaaa cgaaatcatc taccaaaagt taaaaaactt
     3721 gcttaaaaac tgataaaata cttgccaaac ttttcagaat ctgatagact agtatggtaa
     3781 caatctatgg ctcgcaaaga gaccatggca gaaaggaaat attgcaaaat gaaaaaagat
     3841 atccatccag aatatcgccc agttgtcttc atggacacaa ctactggtta ccaattcctt
     3901 agcggttcaa caaaacgctc taacgaaaca gttgagttcg aaggcgaaac ttacccattg
     3961 atccgtgtgg aaatttcatc agactcacac ccattctaca ctggacgtca aaagttcact
     4021 caagcagatg gacgcgtgga tcgtttcaac aaaaaatacg gtctcaaata atgataagag
     4081 aacagtttcg gctgttcttt tttgtttctt gaaatcaact gctgttttca tgttccagac
     4141 tcatctgtag gtttggtttc catgctacta ggcaggaagg aaatagctgt ttcaacacgt
     4201 ccataatgag ctgtactatt gtcacgaacc acactttcat tgatggtcca agtggaattc
     4261 attttcttaa aagcttctcg gactttttcc aaatctttgg aggcaatggc ctgctctaag
     4321 gtttcaaaac gaggacttat actcatctgc tttcacaaag cattctagtc catctccgat
     4381 taacgatggg ctttatcacc tccttctcca gtccttgtat gatatcttaa agttgattca
     4441 tgacatcttc caaagtttga aaggctttat ttttaaatcc acgtttacga atctctttcc
     4501 acacttgttc aatggggttc atctctggtg tgtacggagg aataaatgca aagccaatat
     4561 tagtcggaat ctttaaggta cttgatttat gccatatagc attgtccata acgagtaaaa
     4621 gataatcatc tggataagct tgtgaaagct cttctaaaaa ggcgttcatc cactcagtat
     4681 tacatccacc agctcttaag aaaaatgatt cgcctgtatg ggcatcaaca gctccataac
     4741 aatagcgaaa ttctcgtata tagtgactat ggacatgtgg acctactcct attggagacc
     4801 aacaagatcc cagtttactg attctaccga aaccagcctc atcttggtac atcgagcgag
     4861 ccttatgaaa aggtctactg gttttaaagc gctttctttt cttcttgaat tgagatttta
     4921 tttttagacg cgacaatggt ttgagcgtct gctttcttag gatgttctgg acgtggcata
     4981 atatttcgcc aaccatggcg cttcaacagt tgatagaagg catcacgtgt gtaggaacga
     5041 tataagcctg aaataaggta ttgtaacaaa ttctcctgcc tctgtagcct tcaaatggcg
     5101 ggcaagaaag gctttctctt cctcaactgt catatatgca tggttacgac caccacgtgt
     5161 ttcttgaagg agagagtcga gtccgaactc ctcatatttt tttacatttc gccaaatcgt
     5221 tgtttgatta cagtctaaaa gctctataat ctctttataa gatttgccca tcagacgaaa
     5281 tagaacgatt tgaaggcgtt tatgatattt agctgtacga gagtctttta aaagtgtttt
     5341 gatggcttgg atttcttctt tagttgattt catatcacta ttatataatg ctttttgatt
     5401 ttagtctggt ataaatattg ctttcctcca aaatggtcat aattttacta gcaaatctaa
     5461 catatcacgg ataaattaac aagtgatttc tgaattgcta aacattttct tttcttatag
     5521 cataccatac tttaagattt tgtctttgag aaagatattt ccaagaaaaa cgttcgtttt
     5581 tttatctatt ttcaaaaaaa accaaaaact gaattgaaag aatttttaga aaatttctgt
     5641 tttttcttta cagtgaaaaa aaattctgct ataatgtctt atgtaataaa atatgacaat
     5701 aaaaggagaa cgatatgaca tctgctaaag aatatatcca aagcgtgttt gaaactgtaa
     5761 aagctcgtaa cgggcacgag gctgaattcc tccaagctgt tgaagaattt ttcaacactt
     5821 tggaacctgt atttgaaaaa caccctgagt atatcgaaga aaatatcttg gcacgtatta
     5881 ctgagcctga gcgcgtgatt tctttccgtg ttccttgggt tgaccgtgat ggaaaagttc
     5941 aagtaaaccg cggctaccgt gttcaattca actcagctgt tggaccatac aaaggtggac
     6001 ttcgtttcca cccaactgta aaccaaggga tcttgaaatt cctcggattt gaacaaatct
     6061 ttaaaaatgt cttgactgga cttcctatcg gtggaggtaa aggtggatca gacttcgatc
     6121 ctaaaggtaa aacagatgct gaagtgatgc gcttctgcca aagcttcatg actgaattgc
     6181 aaaaacacat cggaccatca cttgacgtac ctgctggtga tatcggtgtt ggtggacgtg
     6241 aaattggtta cctttacggt caatacaaac gtcttaacca atttgatgct ggtgtcttga
     6301 ctggtaaacc tcttggattt ggtggtagct tgattcgtcc agaagcaact ggttacggtt
     6361 tggtttacta tactgaagaa atgctcaaag ctaacggtaa cagctttgct ggtaagaaag
     6421 tcgttatttc aggttctggt aacgttgctc aatacgctct tcaaaaagca accgaacttg
     6481 gtgcaacagt tatctctgtt tctgactcaa acggctatgt tatcgatgaa aacggtatcg
     6541 acttcgatct tttggttgat gttaaagaaa aacgtcgcgc tcgtttgact gagtatgcag
     6601 ctgagaaagc aactgctact tatcatgaag gttctgtatg gacttacgct ggaaactatg
     6661 acattgcgct tccatgtgct actcaaaacg aaatcaacgg tgaagcagct aaacgtttgg
     6721 ttgctcaagg cgttatctgt gtatctgaag gtgccaacat gccaagcaac cttgatgcca
     6781 tcaaagttta caaagaaaat ggtatcttct acggacctgc caaagctgcc aacgctggtg
     6841 gtgtagccgt ttcagccctt gaaatgagcc aaaacagcct tcgcctctca tggactcgtg
     6901 aagaagttga tggacgtctc aaagacatca tgaccaacat ctttaacaca gctaaaacaa
     6961 cttcagaaac atatggtctt gataaagact accttgcagg agctaacatt gctgcctttg
     7021 aaaatgtagc aaacgctatg attgcacaag gcgtggtata aaaaaaaatt acggaaactg
     7081 actacccaga cgggtagcca gttttttcaa ttcctaaaat ttaagattct aatacccttt
     7141 atgcaaaaat atagaattct acctttttct ttatataggc taatgttttt aatatattta
     7201 ttgtctattt ttgaaaagac aataaaacta ttctactata gattatcatt tcccacaatt
     7261 cataactcaa acctaatatt ttgttataaa acagtagatt ttatttatta tatctggcac
     7321 cttaaaaagt aagaaatata aattaaaatt taaaactctt tttccaattc tctttcaata
     7381 gcttttcgct tgcaatcaat tagtttattc aagtacagta gcaagttaat gtagtctata
     7441 cccgtttcaa atatcttttt aattctttct aggagttctt tttctaattc caacaccgga
     7501 acatgactat cagtataaaa atgtgaatag ggagtaaaat gtatttcttg gaatgacttc
     7561 ttaccaaatc ctttagctct gagaagatta aatagtatta gtttttgatt gttgttttct
     7621 aaaaattcta cacctagatt gaccaatcta attgcagatt gctcattatt tgtttcctcc
     7681 agtatttcta atatgatctg actgtcattt tttataatat catcaatcat attattgtag
     7741 tagtaatatg gcctatttat tgcaaaacgg ataaactttt tataaatttc tttcttatct
     7801 ctaaattcac ttatagaatg taataccatg tatcctaaat tggaatgacc tattctcaat
     7861 tcatcaattt tcttcaatac ttctaccgaa aaatcaacat ctttttcacc taatttttga
     7921 aaaagattat agctgtgatt ctgacaattt tctaaattta ttaaatacca aaacttcaac
     7981 tcttttactc caattagatt tattaatttt ggcacctctt cttctcttat aaaatcagaa
     8041 ataacaaaat ttgtattccc agctttttgt attaacaact cttttaaact aggatctttc
     8101 aaaatcaatc tctcaaaatt taaaattgta aaataacatg gtaaagaatt agcttctaga
     8161 atactcttta atgtttgtag atcttcattt ttaacgtttt caagttgtgt taaataagca
     8221 agttgccatt catatttttc tgattctgga gaggaaacaa taacagactg cattgaactt
     8281 tcctcaatat tttctaaaaa actaatcgga ttcatattta ca
//
LOCUS       DAVKMJ010000066         8281 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000066 DAVKMJ010000000
VERSION     DAVKMJ010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8281
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.066"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            146..793
                     /locus_tag="VW348_001954"
     CDS             146..793
                     /locus_tag="VW348_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEU9746806.1"
                     /translation="MVVGIAIASGYLNSHLDKFVDWGSWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWEASQE
                     GRPNQMSQKQVKLAAIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVR"
     gene            924..1337
                     /locus_tag="VW348_001955"
     CDS             924..1337
                     /locus_tag="VW348_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746807.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISLWECL"
     gene            1356..1541
                     /locus_tag="VW348_001956"
     CDS             1356..1541
                     /locus_tag="VW348_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746808.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRGLTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(1808..2251)
                     /locus_tag="VW348_001957"
     CDS             complement(1808..2251)
                     /locus_tag="VW348_001957"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEU9746809.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKRGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(2281..4503)
                     /locus_tag="VW348_001958"
     CDS             complement(2281..4503)
                     /locus_tag="VW348_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEU9746810.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYPSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            5519..6148
                     /locus_tag="VW348_001959"
     CDS             5519..6148
                     /locus_tag="VW348_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEU9746811.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(6271..8163)
                     /gene="pepO"
                     /locus_tag="VW348_001960"
     CDS             complement(6271..8163)
                     /gene="pepO"
                     /locus_tag="VW348_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEU9746812.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
BASE COUNT         2248 a         1901 c         1589 g         2543 t
ORIGIN      
        1 ttattttcag ggttttattt ctatcatttt attttacttt catttggtgg gagaatattt
       61 gaaaaaaaga aaggtagttt aacctatgaa aaaatcacta aaaatttttg ctacatctaa
      121 atagtttgac ctcttcgggg ttgctttggt cgttgggatt gcgattgcat ctggttacct
      181 caactcacac ctcgataaat ttgtagactg gggatcatgg acagctcttg taccctttgg
      241 attgatttcc gtaaccaacg ttgggatttc catgttgtcc actcgtttca cggggaaatt
      301 aagcaaatgg ggaaattact ttggtattgt taataccatt ttgtccggtg ctattgatta
      361 tatccttgga aataaggcgg ccatcattac ctatcccgtc accttcctca tttatacctt
      421 tgctataaag aagtgggaag cttcgcaaga aggcagaccc aaccaaatga gccaaaaaca
      481 ggtaaaattg gcggccatca tcatttccat catcgccttc ctctttgcct ttgtgaccaa
      541 ctatatcgga tatgggggca agatgaatct ccttgcctac gtaacaacta ttgcctttgc
      601 actgtccctc attgccaatg ctttgaatgc attaaaacta acaactcagt ggggcttttg
      661 gttgatttac aatttcgttc agctgacaaa agctggtatt caaggaaact tcgccaatat
      721 cggtaaatac atcttttata tcctcaatgc aatcggagct ttatttgtct ggaatgatga
      781 agaagttaga taatagaagg aaactcaaat aaagaatact agccaactta agagaatctc
      841 ccttctgcta tttttatcat tttagttgta actcccattc ttttggagta gaatgaagtt
      901 agataaaaga gggaggtctt gtcatgaaaa aactctatag aatccatttt atagcaattg
      961 cagttattga tttgctacta tttgcatttt ttatcactag actcgagaca tcttttgagt
     1021 ggctcttgct ctctggttta attttcttcc ttgctcaagg actcctgcta tttctcttgg
     1081 tcgtccgact caaacatcaa ttcgctgaga tttatcctca aatcaataaa aagattcgct
     1141 tctactattt aggggttctc accattgatt ttctattttt tgttctctta gccttcatta
     1201 gttctcagcg tttttcatct cttatgccaa tcatcactgc ttgccattct actttttatt
     1261 atatgacagc tgactaccta agagaaaact atccagactt ttacgacaaa cacatctctt
     1321 tatgggagtg tctctaagga aaaggaggtt ttagcatgaa aaaaatcatc ttcatcaaaa
     1381 ccattcaact ccttgtcatt gatggaatca tgctggcatt tttgacattt aaaagggggc
     1441 ttacttggga ctggattttg atttatagcg gttggctcat tttctttcat cctgtgctat
     1501 tgacctatct ttcaaaccaa ctttgtgacc actttagtta actctattcc cagattagac
     1561 cgagattctg gcgttttgct ttacaaattc tcctatggga tagcctgatg attctctcct
     1621 tggtgtcttt aagtgatatt ccacttttcc ttcagggaac tctcctcatc ctaggacatc
     1681 tcatcccttc ctatcgcatc tgccaaagcc tgaaaagaga cttcccccaa gcatatcaag
     1741 aaccgatttc tttttggagt attttatgat agatgagaaa gaccaagccg actgggcttg
     1801 gtctttctta tctcttttta gtatctagga taatggtaac aggtccatta ttaaccagct
     1861 caacctgcat atctgctcca aagatgcctg tctgaacggg cacttcttgc gctaattttt
     1921 gattgaaagc atcatagaag tctgatgcca tatcaggttt agctgcccct gtaaaggctg
     1981 gacgattgcc tctcttagta tccgcaaaga gggtaaactg agaaatagag aggatttctc
     2041 cttcaatatc tttgacagac aggttcatct tgccttctgc gtctgaaaaa atccgcatat
     2101 tgaccagttt tctcacagca tagtccaaat cttcctcttg gtcctctggt ccaacaccaa
     2161 ccagcaataa aagtccctga ttgatttttc cctgaatctg gccttctata ctcacttggg
     2221 cttttttaac ccgttggata atgattttca taatagcctt tctagtaaga gctaggacaa
     2281 ctagccgttg gtccgtttga cagagtaaac ttctggcaca ctcttaattt tatcgacaac
     2341 cgtggtcagt gtagagaggt tggcaatacc gaaggacaca tggatattag caaacttcat
     2401 atccttggtt ggttgggcat tgaccgttga aatattcttg gttgtatttg aaagaacttg
     2461 cagtacatcg ttcaacagtc ctgtacggtt gagaccgtag atatcgatat gggccatata
     2521 ctccttattt gagctagggt actggtcttc ccattccaca tcaaggagac gttgctcgta
     2581 gttttcttgg gcacgcaggt tcatacagtc cacacggtga atagccacac cacgaccctt
     2641 ggtaatgtag ccaacaatat cgtcaccagg cacggggtta caacacttag caatccgcac
     2701 taggagacca gaagcacctt caataaccac tcccccctca tgcttgacct tgagggtttc
     2761 tttattttca accttgacct cgccaccttt gacaagctcc tctgcctcag ctttggcctt
     2821 ggcacgctct tcctcacggc gttccttttc agtcagacgg ttaaagacgg taatcgcacc
     2881 gatttcccca aaaccaatgg ccgcaaagag ggagtcttct gtcttgtaac tggtcttttg
     2941 cagaacttga tccatgtggc gcttgtccat aaatttattt gccacatagc cattttcttg
     3001 gaactgagcc atcagcatct cacgaccctt gttgacagac aattccttat cttggttttt
     3061 aaagaactgg cgaatcttat tgcgcgcctt gctagtcttg accatattga gccagtcacg
     3121 gctaggtcca aaggagttcg ggttggcgat aatttcaacc tgatcccctg tctttaactt
     3181 ggttgtcagt ggaaccatgc ggccattgac cttggcacca gttgcttttt caccgacctt
     3241 ggtatggatt tcgtaggcaa aatcaatcgg tcctgaatct ttgggaaggg aacggacagc
     3301 tccatctggg gtaaaaacgt aaatctcctc agccaaatag ttttccttaa cagagtccac
     3361 aaattcctta gcatcatcag cctggtcttg gagctccatc atctccttga tccagttcat
     3421 tccaatagct gattccttgc tgttaacttg cccctttata cctttcttat aagcccagtg
     3481 agccgcaacc ccgtactcag ccacctcgtg catttccttg gttcgaatct ggaattcaat
     3541 cggccctttt ggtccataaa cagtcgtatg gatagactga taaccattgg ccttgcggtt
     3601 ggcgatatag tctttgaagc gacctggcat cggtttccaa aattcatgca cgtaaccaag
     3661 catggcataa acatcacttt gggtatctaa aatacaacga atagcaatca gatcatagat
     3721 ttcctcaaac cgttttctct tgtcctgcat tttgcggaaa attgagtaaa tatgcttggg
     3781 acgaccataa atcttccctt tcaagtgacg ttctgtcgta tactcctcta attttgtgac
     3841 tacctcatcc accaaggcct cacgctccct gcgcttttcc ttcatcatat gggtaatctt
     3901 gtaaaactcc gttggattga gataacggaa agacaagtct tctaattccc atttgacact
     3961 ggaaatcccc aaacgatggg caagcggggc atagatttcc atggtttctt tggaaatacg
     4021 ctcctgcttg tcttttcgaa gatgtttcag ggtccgcata ttgtgcaagc ggtcagacag
     4081 tttgaccaaa ataacgcgga tgtcctcaga catggccatg agcatcttgc gatgattttc
     4141 cgctaattgc tcctcgatcg atttgtactc gaccttgcca agcttggtaa ctccgtcaac
     4201 aatcacccgc acatcaggac caaactctct ttccaaatcg tccaaggtcg catctgtatc
     4261 ttccaccaca tcatgcaaga atccacaagc tactgttaca gcatccagct ttagcttagc
     4321 taaaatacct gccacttgga tagggtgaat gatataaggc tcgcctgatt tgcgatattg
     4381 accactgtgg cattcaacag catagaccaa ggccttatgg acaaaatgaa catcctcttc
     4441 cgttaaatat tctttggtta aagcgacaac ttcttcgcct gttaaattca cttctttcgg
     4501 catctctact ctccaattct tcctaccatt ttatcacttt tttaagaata tgaaaactag
     4561 attggaacag aataagaaaa aaataattca aaattgcttg ataattctga attattggcc
     4621 cataatatac tacgaagtta gattttaaac ttaggtgata gaaggagaga tagaagaacg
     4681 gaaaccatat tgtaacccaa agactttctg atttccccaa ttccattgaa gatacgaaag
     4741 ataaacggtg gaactcgtat cacatacact ggtaccttga ctggattttg gaattaatac
     4801 tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gttgctcaaa gcactgcttt
     4861 gaggttgtag ataagactga caaagtcagt cacatatata cggcaaggcg acgttgacgc
     4921 ggtttgaaga gattgttgac gcggtttgaa gagatttttg aagagtataa aaatcctcaa
     4981 gatactttct tctatccttt agtttataag gagaatacct atgaaaaaaa ctgctatttc
     5041 tatctttgct ctcctaatgt taggagtttg ctgcctgttc ctattcagcc agcaaagcta
     5101 taaaaaactc gttcaatact atgctaacga ccagaacctg cccagtagga taacttatag
     5161 tgaatatagc gacaaatgat aagccaacta cggtagcact ctaaacatca cgtctatcaa
     5221 acaagctaat gacggagttt atgcaaccta tgaagggcaa ttgacacctt tccaatattg
     5281 ataaattgat aaccagcctg tcttcatcta gtcatgctgg tttttaagtt cattttaaat
     5341 ccttacctat tctccctaac tgtgctatac ttaatttata ctcaatgaaa atcaaagagc
     5401 aaactagaaa gctagccgca ggctgttcaa agcactgctt tgaggttgca gataaagttg
     5461 acgcggtttg aagagatttt cgaagagtat tagtacattc tttgagattg gagctagtat
     5521 gaaaatccat aaaaccgtga atcctgttgc ctatgaaaat acctattatc tagaaggcga
     5581 aaagcacctc atcgtcgtcg atcctggtag tcattgggaa gccattcgtc agacaatcga
     5641 gaagatcaac aaaccgatct gtgctattct cttgacccac gcccattatg accatatcat
     5701 gagtctggac ttggttcgcg agacgtttgg caatcctcct gtctatatcg cagagagcga
     5761 agccagctgg ctctacactc ctgtcgataa tctctccggt ctccctcgcc acgatgatat
     5821 ggcagatgtg gtcacaaaac ctgcagaaca cacctttgtc tttcacgaag aataccaact
     5881 agaggaattt cgttttaagg ttctaccgac cccagggcac tctatcggtg gtgtttccct
     5941 agtctttcct gatgctcacc tagtcttgac gggagatgct ctattccgcg aaactatcgg
     6001 acggaccgac cttccgactg gtagcatgga gcaactcctt catagtatcc agacccaact
     6061 cttcacccta ccaaactacg atgtctatcc aggacatggt ccagctacta ctatcgctca
     6121 cgaaaaggcc ttcaatccct ttttctagca agatgatgac aatcgaaatt taagtaaact
     6181 atccagcaaa tctttctatt acaaaaggca tcctatcaag gttttcacac gtgattggat
     6241 gccttttttc tgatgactag attttttgta ttaccaaata atcacgcgct cctctggtga
     6301 acgccacatt ccgtctcctt ctttgacatc ataggttgta aagaaatcgt cgaagtttgg
     6361 tacttgcaca ttgacacgga gtttggctgg tgcgtgcaca tcgacgctag ccaaaagttt
     6421 cataaattct ggtcgacctt tcatgcgcca gatgcgaccg aagttgtaga agaactcttc
     6481 tgctgagaag tctgcttctc tcttagctgc ttcaagcgct gctgcgattc ctcccaagtc
     6541 agccacgttt tctgatacag tcaatttacc gttaatggtt gctccataag aatcctgtcc
     6601 atcaaattgg tcaatgactt tttgtgtttt ctccttgaag gcagcatagt cgctctctgt
     6661 ccaccaatcc ttgaggctac cattttcgtc aaaggaagcc ccgttagtat caaaggcgtg
     6721 ggaaatttca tgggcaatca ctgccccaat accaccgtag ttagcagaag atgactgatg
     6781 caagtcatag aaaggcgcct gtaaaatggc cgctggaaag acaatcaggt tcttctgagg
     6841 attgtagtag gcattgacca tatgagcagg catgccccat tccttatagt ctacaggctg
     6901 gttccactta ctccaactgt gcttgatttc cacacgcgca aaggctagag cattctcaaa
     6961 aagactggca gtttcattca ctaccttatc cttgtaacgt gcaggcaatt cttctggata
     7021 gccaatataa ggtttgatca cattgagctt cacgatagcc tgtttacagg tttctggagt
     7081 gagccagtca ttcttaagca gacgctcctt atagacatca atcatggttg ccactttttt
     7141 ctccacatcc gccttggctt ctggagagaa cttctcacgg gcgtaccaaa gacccagggc
     7201 ttgcttgaaa ggttcttgtg ctagatgata agctgctttg accttatctt ttgcctctgg
     7261 aactccagaa agggcacggc tgtaggcacc agacaaaaca cggatatcct ctgttaaata
     7321 gctggttgaa agattgacaa cactcaaaat caaggttgct ttaaggagag accaggcttc
     7381 ctcactgtag aattgctctg ctgcttgcca gaaacgttcc tcgtctacaa taaccttgtc
     7441 tggtaattgc ccaataactg ctttgaagaa gtcatccaaa ggtagggcag gcgcgaattt
     7501 cttaaaatct tcgtaagaat atggatgata gagtttagca tattctgaac tttcttcatt
     7561 agagagcacc actgccgcaa ctcggcggtc caattcaagt cttttttcta gcaagtcttc
     7621 aatttcttca tcagagaaat cataagcctt gaggagattt gcgctgcttt ctttccaaag
     7681 agtcaagagc tcttcgcgct gaggatgttc ttctgcatag taggtcgtat ctggcaagat
     7741 tgtgcttgga gcgctagccc atagaacatt gattctagca tccataaagt ctggcgatac
     7801 accaaaagga aggaagtttg gttttcctgc aagctcaaac tctgctagtt tagctgtaaa
     7861 atccgcaaaa gtttccaatt cttggaattc tttaaggagt ggtaagacag gtgtgatacc
     7921 gtcagcttct ctcttgtcaa aatcacgaac taggcggtgg tatttgacaa agttttccaa
     7981 gatagcatcc tcaggcactt cttcacctgc taaccacttg tctgttgtcg ccagcatcag
     8041 gtcttcaatt tcctggtcta aatcaacaaa acctccagtt tgagacttat ctgctgggat
     8101 ttcagctgtc tgttgccatt ctccattgat agcatcataa aaatcatctt gataacgtgt
     8161 catcttgttc tcgctttcat ttgtatttgc atttatctta acaaaaatca ctagggaatg
     8221 caattaataa ccatttaact attatttttt agctattata aaaaatcttt ccatgataaa
     8281 a
//
LOCUS       DAVKMJ010000067         8163 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000067 DAVKMJ010000000
VERSION     DAVKMJ010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8163
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.067"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            52..1077
                     /locus_tag="VW348_001961"
     CDS             52..1077
                     /locus_tag="VW348_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEU9746813.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1067..2074
                     /locus_tag="VW348_001962"
     CDS             1067..2074
                     /locus_tag="VW348_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU9746814.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            2074..3081
                     /locus_tag="VW348_001963"
     CDS             2074..3081
                     /locus_tag="VW348_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEU9746815.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFVLLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            3081..3875
                     /locus_tag="VW348_001964"
     CDS             3081..3875
                     /locus_tag="VW348_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9746816.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            4263..4688
                     /locus_tag="VW348_001965"
     CDS             4263..4688
                     /locus_tag="VW348_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEU9746817.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYIEDLKLKCNIANYNI"
     gene            4744..5061
                     /locus_tag="VW348_001966"
     CDS             4744..5061
                     /locus_tag="VW348_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000968321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3847 domain-containing protein"
                     /protein_id="HEU9746818.1"
                     /translation="MMASKRLSIEEQIEKKEESIKQLQNQKRQLKKKLNEQERKARNK
                     RLIEKGAVFESIFEESIDLTKDEFYKLIKTLNDEEIRLNIMEILEERIDDNVEKSSKD
                     EIT"
     gene            5371..6759
                     /locus_tag="VW348_001967"
     CDS             5371..6759
                     /locus_tag="VW348_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000785367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HEU9746819.1"
                     /translation="MADSFHFSVNIISRGKGKSAVASAAYISGEKIKNEWDGVTHDYT
                     RKEKILVKNIILPDHIPKEFNDRSTLWNKVEMAEKNSNAQLARQFIIGLPKELSLSEN
                     KNLVERYIKENLTSQGMIVDYAIHDESQDKNGNIHCHIMTIMRPINEKGEFLAKSKKE
                     YILDEKGEKVLNKNGKPKTRKVELTTWNDTGNVEQWRENFSDLCNKYLERAGAEKRVD
                     HRSFKRQNSDYLPTIHLGSAASAMERKGIETDKGNYNREIRKYNQLVKTIKEEIKTLK
                     GWIGNLLDNLSTAYEKFKDIERDKVIDNPKLFNLTNYLLTYSEIQKEKSKYLKGYAKT
                     NKEKYDFKKLTSAYSYLRKNNIETIGQLQTKIETLKSNSYRLNKKAKTIHKEMEDVEK
                     KILYYEIYKAKKEVYEEYQKKNIFTKEAFYNKHKKDIDQYKVVSGKLKKLLSDKEKLS
                     PKKWNEEKILLM"
     gene            7085..7258
                     /locus_tag="VW348_001968"
     CDS             7085..7258
                     /locus_tag="VW348_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019118552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746820.1"
                     /translation="MNKRQELIDELIKANEDGTYKTYKSTEEIKAMNNEEIQIIYSNM
                     KNYLSDKRTHINY"
     gene            7444..7971
                     /locus_tag="VW348_001969"
     CDS             7444..7971
                     /locus_tag="VW348_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEU9746821.1"
                     /translation="MINEEISKEAGQAAQTIISYTIKATKESINLEKEIRKKMNETLE
                     KANGNLKSLMGDEMKIKDLYKKGQLENISIDQIDLKDLKKELNKLGVSFSVMKNKESK
                     NYEIFFQAKDIKVMEYAFKQVIAKENKKEKESILKQIKKYKDLSKNKDKTKEKGKRKV
                     KEKVKPNKKDMTREI"
     gene            8098..>8163
                     /locus_tag="VW348_001970"
     CDS             8098..>8163
                     /locus_tag="VW348_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEU9746822.1"
                     /translation="MATNKRYYWIKLKEEFFTDKRI"
BASE COUNT         3471 a         1097 c         1343 g         2252 t
ORIGIN      
        1 atgataatta ttatcgatac aatagacttg aaatatgttt aaggagtttt tatgaaaaac
       61 aaattttttc taatagctat tttagctatg tgtatagttt ttagcgcttg ttcttctaat
      121 tctgttaaaa atgaagaaaa tacttctaaa gagcatgcgc ctgataaaat agttttagat
      181 catgctttcg gtcaaactat attagataaa aaacctgaaa gagttgcaac tattgcttgg
      241 ggaaatcatg atgtagcatt agctttagga atagttcctg ttggattttc aaaagcaaat
      301 tacggtgtaa gtgctgataa aggagtttta ccatggacag aagaaaaaat caaagaacta
      361 aatggtaaag ctaacctatt tgacgatttg gatggactta actttgaagc aatatcaaat
      421 tctaaaccag atgttatctt agcaggttat tctggtataa ctaaagaaga ttatgacact
      481 ctatcaaaaa ttgctcctgt agcagcatac aaatctaaac cttggcaaac tttatggaga
      541 gatatgatta aaattgattc aaaagcctta ggtatggaaa aagaaggtga tgagttaatc
      601 aaaaatactg aagctcgtat atccaaagaa ttagaaaaac atccagaaat caaaggaaaa
      661 atcaaaggaa aaaaagtatt atttactatg attaatgctg cagatacatc aaaattctgg
      721 atttatacta gcaaagatcc aagagcaaat tatttaacag atttaggtct agttttccct
      781 gaatcattaa aagaatttga gagtgaagat agttttgcaa aggaaatttc tgcagaagaa
      841 gcaaataaga taaatgatgc tgatgtaatc ataacttatg gtgatgataa aactcttgaa
      901 gctttacaaa aagatcctct tttaggtaaa ataaatgcaa ttaaaaatgg tgccgttgct
      961 gtaattccag ataatacacc gttagcagcc tcatgcactc caacaccact ttcaataaac
     1021 tatactattg aagaatacct aaatctttta ggaaatgcat gcaaaaatgc gaaataaaaa
     1081 acaaataaac ctaggcataa tttttgtaat ctgcctaggt cttcttatta caatattttt
     1141 gtcattaaag cttggaacaa aagaaattaa tatcagagat tttttagcag cttttggaat
     1201 gggtaataca aatgatgatt ttattaaatc aattatatat aaaagaatac ctagaactat
     1261 ttttgcaatt ttagcaggtt ctagtcttgc cataagcggt gtattgatgc aatcagttac
     1321 tagaaaccca atagctgatc caggtatact cggtataaac acaggagcaa gtcttagtgt
     1381 agtaattggt ctttcttttt taggaatttc atcaagcata agccatataa gttttgcaat
     1441 cattggtggc ttagtaagtg caatttttgt atacgcgatt gctgtaagcg gaaaagcagg
     1501 ccttacccct ataaaacttg ccttatcagg aacttgtgtt agtatggctt taagcagttt
     1561 tgtaagtttt ttaattttac cgaataataa cgtcttagac aaatttagat tttggcaaat
     1621 aggtagcctt ggagcagcta cattatcttc tatatctaca ctactacctt ttataatttt
     1681 aggtcacttg atagctatat ttatttcatc agatttaaac gctttagcta tgggtgatga
     1741 aatggctgtt ggtcttggag ttaatgttaa taggataaga tcacttgcaa taattgcaag
     1801 tgtgctttta tgttcaagta ttactgcaat tggtggacct attggcttcg taggtcttat
     1861 agttcctcac ttttgtggct tatttataag caaagatata cgcacaatga ccatttcttc
     1921 atcttttata ggtgcagagc tcttgcttat atgtgatata atcggccgta tgttaggtaa
     1981 accaggtgaa attgaagtag ggataattac tgcaataatc gggggtccag tacttattta
     2041 tgtaactatg aaaaatagag gggttaataa ctaatgcaaa atttaattat aggtattcaa
     2101 aaaagaaaaa atagaataac actattttcc tcactatttt tattaataat aatcagtcta
     2161 tcatttttcg ttttacttat cggagatgaa agttattctt tttcaacttt gattaaagtc
     2221 ttaaatagtg aaactgttcc tggagctagt ttttcgatta tggaaattag attaccaaaa
     2281 ttattagcag gaattatagc tggctggtct tttggattgg caggatttat ctttcaaact
     2341 atgttaagaa atcctcttgc aagtcctgat ataatcggtg tcacaagttc ttcatctatt
     2401 gcagcggtct tttgcatatt ggtattaaaa acaaatagtt taactactgg aattatttca
     2461 ataacttgtg gactaacatc atctttaata ttatttttac tagctaaaaa agatggtttt
     2521 tcagcagcaa gactgataat attaggcatt ggttttcaag ctgtcacaag agcaggcacc
     2581 tcatttttat tgttgaaagt agcaagatat gaattacaag aagttatgag atggctcagt
     2641 ggctctttat cttttacaaa gttagatgac atacctcttg ttctaatagt aagtattatt
     2701 gctactatat tagttttatt ttttaataaa agactagaaa ttattgaact tggtgaagaa
     2761 atagcaatcg gacttggagc aaatcccgag ctttcaaggc ttgttttaat tttttgcgct
     2821 gtatctttaa ctgctttttc tacttcaatt acaggaccaa tagcttgtat atctttttta
     2881 gctggtccca tagccttaaa tattggcaag aaaagaagcc caatattagc tggattggtt
     2941 ggaattttac tagttttgtt atcagacata ttctctcaaa atattttacc agctagatat
     3001 ccagtaggtg ttgtaactgg cttgttaggt tcaccatact taatatattt actaataaaa
     3061 atgaacagga ggaatatata atgaaaggtc tgtggtcaaa taatcttacc tgcggttatg
     3121 atgaaaaaat aatcttggaa aatataaata taaaaatacc tgaagaaaaa atatcagtta
     3181 ttattgggtc aaatggttgt gggaaatcaa cactcattaa aaccttgtct cgacttataa
     3241 agccattaga gggagaagta ttgcttgata ataaatcaat taattcttat aaagaaaaag
     3301 atttagcaaa acacatagct atattacctc aatctccaat aatccctgaa tcaataacag
     3361 tagctgatct tgtaagccgt ggtcgtttcc cctacagaaa gccttttaag agtcttggaa
     3421 aagatgacct tgaaataata aacagatcaa tggttaaggc caatgttgaa gatctagcaa
     3481 ataacctagt tgaagaactt tctgggggtc aaaggcaaag agtatggata gctctagccc
     3541 tagcccaaga tacaagtatc ctacttttag atgagccaac tacttacttg gatatctcat
     3601 atcaaataga actattagac ctcttgactg atctaaacca aaaatataag acaaccattt
     3661 gcatgatttt gcacgatata aatctaacag caagatacgc tgattaccta tttgcaatta
     3721 aagaaggtaa acttgttgca gagggaaagc ctgaagatat actaaatgat aaactagtta
     3781 aagatatctt taatcttgaa gcaaaaatta tacgtgaccc tatttccaat tcgcctctaa
     3841 tgattcctat tggcaagcac catgttagct cttaataatt gaatattgga attcatttaa
     3901 aagtcgcaaa ttttgaactg accctcaaaa gttaggccaa aaaactaact aaaggaggtc
     3961 agttttttaa tggcaaatac agcacagaat ttaagataaa attagtaaaa gaatatcatg
     4021 aatgaaaaat aggatataga gaataacagc aatattaaaa agatcaggac tgataataaa
     4081 caaaaagaaa gtacaacgac tagttcaaaa gctaaaactt caagtaaaaa gttattcaag
     4141 aaaatctaga aaatactcat cctacaaagg acaggtagga aaaatatcag acaacaaaat
     4201 aaaaagaaat atttattacc gaaaaaaagg ggaaatcgag tcaagtacca acaggctcat
     4261 ctattccaaa aagatattta ctcgatggaa aaactcctag aattagtgct acaaatattg
     4321 acaatggtat cttaggttac tacgaagata tagatgataa aaattataga gtttttgaaa
     4381 attttatatc tgtttcattt ttaggagcag tcttttatca taaatataaa gcaagcctag
     4441 atatgaaaat tcattgttta aaattaaaaa ataaagaatt gaataaagaa gtagcattct
     4501 atttaacttc aattattagg caagctttaa aaaatactga atataaagat caaatatcta
     4561 gcacagtatt gccagatatc aaaattaaat taccgataga cagtagaggt actccagatt
     4621 ggaattacat ggaaagatat atagaagact taaaattaaa atgcaatata gcaaattata
     4681 atatttaaaa taagaacgat tagaaataaa aatctagtcg ttttttattt taagaaagga
     4741 tacatgatgg caagtaaaag attaagtatt gaagaacaga ttgaaaagaa agaagaaagc
     4801 attaagcaat tacaaaatca aaaaagacag ttgaagaaaa aacttaatga acaagaaaga
     4861 aaagcaagaa acaaaagact tatagaaaaa ggtgcagtgt ttgaaagtat ttttgaagaa
     4921 agtattgatt taacaaaaga tgaattttat aagttaataa aaacgttaaa tgatgaagaa
     4981 ataagattaa acataatgga aattttagaa gaaagaatag atgataatgt agaaaaatca
     5041 tctaaagatg aaataacata attgtccctt ggttacaagg gcgcaattat acaccctaaa
     5101 gggtgcttgc gtcctgcgga gtcaaaccct tgcagggagc aacaaccatt cgctttttaa
     5161 aagtcaaggg taaataaact cgctaaggct cgcccttgac ttttaaaatt tgaaatgaaa
     5221 gtaacaatta agccgacata ctgaaacaac aaaaattaat tcagtagtcg gcttttttta
     5281 ttctatcatt tcaaaacgct cattcacaaa gaggatataa aaaaactatt aagcctccac
     5341 ctaaaacaac aaagaaagga agtgataaaa atggcagaca gttttcattt ttcagtaaac
     5401 ataatatcaa gaggaaaagg caaaagtgca gtagcaagtg cagcatatat aagtggagaa
     5461 aaaataaaaa atgaatggga cggagtaacc catgactaca caagaaaaga aaaaatatta
     5521 gtaaaaaata taatattgcc tgatcatata ccaaaagaat ttaatgatag gtctacctta
     5581 tggaataaag tagaaatggc agaaaaaaat tctaatgcac aactagcaag acaattcata
     5641 ataggactac caaaagagtt atctttaagt gaaaataaaa acctggttga aagatatata
     5701 aaagaaaatt taacatcaca aggaatgata gtagattatg caattcatga tgagagtcaa
     5761 gataaaaatg gaaatatcca ttgtcatata atgaccataa tgcgaccaat aaacgaaaaa
     5821 ggagagttct tagccaagtc aaaaaaagaa tatatcctag atgaaaaagg agaaaaagta
     5881 ttaaacaaaa atggaaaacc aaagacaaga aaagtagaac taacaacctg gaacgataca
     5941 ggcaatgtag aacaatggag agaaaatttt tcagatcttt gtaacaaata tttagaaaga
     6001 gcaggagcag aaaaaagagt agaccatagg agttttaaaa gacaaaattc agattatcta
     6061 ccgacaatcc atttaggatc agcagcaagt gcaatggaaa gaaagggaat agaaactgac
     6121 aagggaaact ataatagaga aataagaaaa tataatcaac ttgtaaaaac aataaaagaa
     6181 gagataaaaa cattaaaggg ttggatagga aatttattag ataacttatc tactgcttat
     6241 gaaaaattta aggatatcga aagagataag gtaatagaca accctaaact ttttaatcta
     6301 acaaattatc tattaactta ttcagaaatt caaaaagaaa aaagtaaata tctaaaagga
     6361 tatgcaaaaa ctaataaaga aaaatatgac ttcaaaaagc taacaagtgc atatagttat
     6421 ttaagaaaaa acaacataga aaccataggt cagttacaaa caaaaataga aactttaaag
     6481 tctaatagtt ataggctaaa taaaaaagca aagacaatcc ataaagaaat ggaagatgta
     6541 gaaaagaaaa ttctatacta tgaaatctac aaagccaaaa aagaagttta tgaagaatat
     6601 caaaagaaaa atatattcac aaaagaagca ttttataaca aacataagaa agatatagac
     6661 caatataaag tagtaagtgg gaaattaaaa aaactcctat cagataagga aaaactaagt
     6721 cctaaaaagt ggaatgaaga aaaaattctt ttaatgtaaa atcttgaaga aataaataaa
     6781 gaaaaagaca agataaaaga tgaataccag gaaattaatc atataaaata ttcagtagat
     6841 tttgtaaaca aagaacttgg tatagattta tccatagaaa tagataagct aataaaacag
     6901 ggagaaaaac caagtgtaat agcacagatt aaaaagttcc aagaccaagt caataaagat
     6961 aatgaataca gagaaatgat gaaaaacaag aaaatggatc aagaaagata agacctggta
     7021 aaaatatctt atccaagcta taatatgacc aaacaactaa agtcagatct aggaggtaat
     7081 agagatgaat aaaaggcaag agctaataga tgaactcata aaagcaaatg aagatggaac
     7141 atacaaaacc tataaaagca cagaagaaat aaaagcaatg aacaatgaag aaatacagat
     7201 tatatattcc aacatgaaaa actatctatc agacaaaaga acacacataa actattaaag
     7261 gtggaaaggt agtgtaagct atttttaaaa gtataaaagg tacaaagacc taagaaatat
     7321 ataaaaacat caaaataaag tattccacca ccaagaacaa taaaataaaa acaagcaaag
     7381 ggaagtatag aaaaattaaa acctatactt ccctttttta attcaaacaa aggagagaaa
     7441 agcatgataa acgaagaaat aagcaaggaa gcaggtcaag cagcacaaac cataatatca
     7501 tacacaataa aggcaacaaa agaatcaatc aatttagaaa aagaaataag aaaaaagatg
     7561 aatgaaactt tagaaaaagc aaatggaaac ttaaaaagtc ttatgggcga tgaaatgaaa
     7621 ataaaagatc tctacaagaa aggacaacta gaaaatataa gcatagatca aatcgacctc
     7681 aaagacttaa aaaaagaact aaacaaactt ggagtaagtt tctcagtaat gaaaaacaaa
     7741 gaaagcaaaa actatgaaat attcttccaa gccaaagaca taaaagtaat ggaatatgcc
     7801 tttaagcaag tcatagccaa ggaaaataaa aaagaaaaag aaagtatcct aaaacaaata
     7861 aagaaataca aagacctatc caaaaacaaa gataagacaa aagaaaaagg aaaaaggaaa
     7921 gtaaaagaaa aagtaaaacc aaacaaaaaa gatatgacca gagaaatcta aagggagtaa
     7981 cgaaaagtta cacccttaaa taaccataat aacaagactt ccgaaaaaca gaagtccaga
     8041 attccgaaaa tcggaaatca agaatttcga ttatcgaaaa tcaagaaagg agcagatatg
     8101 gcaacaaaca aaagatacta ttggataaaa ttaaaagaag aatttttcac agacaaaagg
     8161 ata
//
LOCUS       DAVKMJ010000068         7815 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000068 DAVKMJ010000000
VERSION     DAVKMJ010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7815
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.068"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(177..1592)
                     /locus_tag="VW348_001971"
     CDS             complement(177..1592)
                     /locus_tag="VW348_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEU9746823.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAKLLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1605..3443)
                     /locus_tag="VW348_001972"
     CDS             complement(1605..3443)
                     /locus_tag="VW348_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEU9746824.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVIPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     DVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDESVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3461..4303)
                     /locus_tag="VW348_001973"
     CDS             complement(3461..4303)
                     /locus_tag="VW348_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEU9746825.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKIGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLT
                     KNLD"
     gene            complement(4603..7281)
                     /locus_tag="VW348_001974"
     CDS             complement(4603..7281)
                     /locus_tag="VW348_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEU9746826.1"
                     /translation="MAVFVSLDGIVVEVLDVFSSFDGDSEFFLCKRLKDKSQFVMERS
                     RFEEMFQLQSSHLTTQEKLQLFTSVFAGRYDVYAKNFINEQGKIQYFPSYDYGWKQLP
                     PEKRSFQTLTNSVLKSHFRGETAIGIFPMHLDDSCHFLVLDFDEGDWKEAGLTIRRIA
                     RERQMEAHLEISRSGHGLHIWFFFEEAIPSREARLFGKKLIELAMQESMQLSFDSFDR
                     MFPNQDVLPKGGFGNLIALPFQGEAYHQGRTVFVDEQFQPYEDQWRYLQEIQRVSTAK
                     VALLIQEELGKQELDKGLKIVLSNMIQLEKSSVTPKTLFFLKNMASFSNPEFYLKQAM
                     RQPTYQIPERMYLFGESDHYLWLPRGLLYPLQDKFKQVVVEDRRKVQRSISVEFKGEL
                     TFEQELALSDMTSKENGLLHAETGFGKTVLGAALISERKTKTIILVHNKQLLDQWLDR
                     LNCFLTFEEEEAIRYTASGREKVIGYVGQYGGTKKWLSKLVDVVMIQSLFKLENSQSL
                     LDEYEMMIVDECHHVSALMFEKVVAQFRGKYLYGLTATPERKNGHEPIVFQRIGEILH
                     TADKRETDFKRQLQLRFTSFGHLEIEKTKASNFIQLSDWIATDSARNQLILKDILAQV
                     AEGRNILVLVNRIQQIDVFEKLLKEKEVDDCYIISGKTKVRERTSLLETLEQLDKGFV
                     LLSTGKYIGEGFDLPQLDTLILAAPFSWKNNLIQYAGRIHRNYKDKSLVRIFDYVDIH
                     VPYLEKMFQKRQVAYRKMDYRAIEGEEKQFVYVDSRYEKVLIEDLAGERQECLLILPY
                     VHQTKLMNFLKEFRISQIEICIPETVANKAWLDQLKSQKIKVSFTQSKIVTPILLVNK
                     TIVWYDAMPLLGKVDEMTILRLESASIVSELVAGLR"
     gene            7530..7815
                     /locus_tag="VW348_001975"
                     /pseudo
     CDS             7530..7815
                     /locus_tag="VW348_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2578 a         1617 c         1090 g         2530 t
ORIGIN      
        1 ataaccaatc tatcctaagt taactattta taatcggctc tctgtaacaa aattaaatta
       61 attaatcccc ctataaaata aagaggttta gaatttgatg tcttccaaac ctctttattt
      121 catattcaat gagatgttgc cttaaccgtg ataatatcta atcatcaata aacaaactat
      181 ttgaataagg attctccatt tgattcaatc actcctttat accaagtaaa ggacattttc
      241 ttatatcgat tgaatgtgcc atttccatca tcatttcgat caacataaat gagaccgtac
      301 ctcttagaaa gctgtgcagt ggacatagaa acgcagtcaa tacatcccca agacgtatag
      361 cccataattt ccacaccatc ttgtagagct tcagctactt gcaataaatg ttctttcata
      421 tactgaattc tataatcatc ttggactgtt aagttattaa attcatcttt tattagttga
      481 tctttagcac ctaatccgtt ttccactata aataatggaa tttgataacg gtcataatat
      541 ctatttaaaa ttatacgtag tccaattgga tcaatttgcc atccccactc agaagactct
      601 aaataaggat ttactaagcc accaataata ttcccttctc ctgaattata ctgtgttgga
      661 agagcagatt gagtcacact catgtaatag ctaaaggata aaaaatctac ggtataattt
      721 tttaataact ttgcatcttc agctgcaaac tctatgttaa tgtcattttc cttaaaatat
      781 ctttttgcat aattcggata ataacctcta acatgcacat ctgaaaatag ataatttaga
      841 ttctcatact catgagtcgc ccatacatct tttggatttg gagtcattgg ataagctggc
      901 atagctaata ccatacaccc caccttaaac tctgaattaa tctcacgagc aatttttgta
      961 accaaactcg aggcgactaa ttcatgatgt atagcttgat ataattcttg tttcgaaaga
     1021 ttctccttag gtatatctat tcctccacta gtaaacggta attccaaaac agagtttact
     1081 tcgttaaatg taagccaata tttaacttta tctttatacc tttctaaaac tgttcgagca
     1141 aatttttcat aaaaatgaat cattctccta tcaatccatc catgatattt tcttgctaaa
     1201 tataatggag tctcatagtg tgaaagagtt acaagtggtt ctatcccgtg agcatgtagt
     1261 tcatcaaaca attcatcata atatttcaac ccagcttcgt taggttcttc ctcatctcct
     1321 tttggaaaaa ttctactcca tgcaatagaa gtacgaaaaa cattaaagcc catttcagaa
     1381 aacaaggata tatcttcctt atatttatga taaaaatcaa tacctatcaa ttttaagtta
     1441 tcttctgtag gattttctgt tgcttctcct aatccacctt tgggtaacac atcctgaact
     1501 gataagccct taccatcttc attatatgct ccctctactt gattagctgc aacagctcca
     1561 ccccaaagaa aatcatctgg aaaaatggtc ataactttcc tccattataa tattaccagt
     1621 aattccttag aatgctcgat tgtctgatta ttaggtaata ctaatacatc tagaaaatca
     1681 ttggtattcg ttacaattac tggtgtaact gtttcgtagc ctttagtctt gattaaattc
     1741 aagtccattt caaaaatcaa ctgatttttg aaaactctgt ctccttcttc tacatgacta
     1801 ataaaacctt gaccttttag ctcaacagta tctaatccaa tatgaattag taactcaaca
     1861 ctctcatcac tcttcaatcc aattgcgtgc ttagtcggaa aaatatttgt aattttccca
     1921 tcaaatggtg cataaacctt accttcactt ggaataatcg ctactccgtc tccaattagt
     1981 ttatctgaaa atgttttatc ctggacatcg cttaacggaa tgatttctcc tgatatagga
     2041 gaaaatatca tttttttatt tgaaactcca gctttaactt ctaaattgct agaactctct
     2101 tcttcatcga ttccaaatat ataagctaat acaaaggtaa taacaaccga aataaccgcc
     2161 acaattaaag catttacaat atttgatggt acatcagaat aaataaattg aggcaacgct
     2221 atcaaagatg ggacagcaaa tagatacgct ttaacactag taagacctgc aaataatccc
     2281 gctaatccac caccaatcat agctgcataa agcggttttt tatattttaa agtcacacca
     2341 tataatgcag gttcggtaat ccctgcaagt aaggctgaga aacctgctgc aaaagcaatt
     2401 tgttttgtat tattattttt actctttaat gcaacagcca tcgaagcagc cccttgagct
     2461 aagtttgacc ctaacattgc tggaagaatt aatacgtctg gagtagcaat agatgccgcc
     2521 aaaaaaatag gtgcaaaagc ccaatgcatt ccagtcataa caataaatgg cataatagca
     2581 ccaagaatag ctaatgtaag ccatccagct acatcataca tttgcccaac tagatttgat
     2641 aatccttcac caacaattac tccaataggc ccgactacaa ctaaggcaat acagcttgat
     2701 actaataata ctagcgtagg ttgcaaaaaa ctcttagtaa cagctggtgt taatttagca
     2761 atcatttttt caatatattt catcaaccaa accataataa gaattggaac gactgacgaa
     2821 ccataactag ctggtatcac aggtacacca aataaactaa gaggattccc tgattgcacc
     2881 atttgaacaa aatttggatg gagaagtaca cctgctacag acatagctaa tgtagatgtt
     2941 acttttaatt tttgtgatgc agaataagct aataacagcg gtaagaaata atatggagca
     3001 tccccaaaaa atgtcaaaaa agcaatagtc tgagaatctg attgcaatat accaagcatt
     3061 ggtaaaataa ttaccaagac tttcagcata cctcccccta acattgctgg aatgattgga
     3121 gtcatggaac cagcgatata ctcaatgatt ctttctaaaa tattcccttt gtgcccttga
     3181 acaactgaat cggattcaaa attgccaagt ttaacgaatt ctttataata attagctaca
     3241 tcattaccaa gtataatttg atattgtcca ttctttttca taatacctat tacacctggt
     3301 atcttcttca catcatcatc attgactaaa ttttcatctt ttaattctaa tcttaaacgt
     3361 gttacacaat gggtaactct attgacattt ttttcacctc caattacatc gaggattttt
     3421 tgtaccttat ctttataact catggtattc tcctattcta ttaatctaaa ttttttgtta
     3481 agcgacgaat atgagccatc aaataaacta attcactaga agtcagcaaa taattgtact
     3541 cagtttgtat aaacattgcc acctgttcac cacattcata ttctctagga tatttatttt
     3601 tcattaatgc taacaagtct tcatcatcat catcgtcaca ataagttgta ttttcaacca
     3661 agcgatgggc aaataatttt atatgagtta tgaatctata ataatcaata gaatcttggt
     3721 taaactcagt acaatagaaa tcttgaatga ttttctcaat tcccataatt atttcagtga
     3781 ttttatacga ctcttgaaaa ttattttcta aattagcatt aacaaaatgt agcgctatga
     3841 atgcagcttc gtcaattgga agttcaatac ctaactcttt ttttattatt tgtaaagccc
     3901 ttttcccaag ctcaaattct tctttataat atttcgagat ttcccagcgt aggggattcg
     3961 aaataataac tccttcttta taacgttcta tactcgaaga aatatgatcc gttagattta
     4021 tatagataat ctcatcaaaa ttattaccta atgttatttt acctagatta attatttttt
     4081 cggtgatgta caccaactcc aaaggaacgt taataaacat ctctgtaaaa cgggtcatat
     4141 tatctctatt tttgagaaaa aaacttttct caatatcaat tggatttact ttatctccaa
     4201 tttttcttcc aaaagctatt ccccttccaa aaagaagaat atcgatatct tttttacttt
     4261 gcgcaattac ggcattgtgg tttagtattc gttttatgat cataaaattt cccttttaaa
     4321 ataaaaggaa cctacttaaa aacatcaaga aacttcttct gatgtgatta aataggttcc
     4381 tgctcacttg tattagtgat aacatccttt tatttcaatt tttaatggtg acatgaagct
     4441 taaataatta ataactctgt aaccattttc attttaagat atttcaatct atttgtcaag
     4501 tacttgtaga aattttttta ttttgtgtga ttcgaatgtg ataatggcaa cagtctcact
     4561 aaagaaatga aaatcataca tagaaatttt taaaaatttt ctctatcgta aacctgccac
     4621 tagttcagaa actatactag ctgattccaa acgtaatatg gtcatctcat ctaccttccc
     4681 taataatggc attgcatcat accaaacaat agtcttattc accaaaagaa taggcgttac
     4741 tatttttgat tgagtaaaag acactttaat tttctggctc ttcaactggt ctagccatgc
     4801 tttatttgca accgtctctg gtatacatat ctcaatttga ctaatcctaa attcttttag
     4861 aaaattcatc agttttgtct ggtgcacata aggtaaaata agcagacatt cctgtctttc
     4921 ccctgctaag tcctctatca acaccttctc atatctacta tcaacataaa cgaattgttt
     4981 ctcctcaccc tcaatggcac gataatccat ctttcgataa gctacttgtc gtttctgaaa
     5041 catcttttct aaataaggaa catgaatatc cacataatcg aaaatacgca ccaaagactt
     5101 atccttgtag tttctatgaa tccgacctgc atactgaatt aaattatttt tccaagaaaa
     5161 gggtgctgcc aagataagcg tgtccaactg aggtaagtca aaaccttcgc caatgtattt
     5221 tccagtagac aacaaaacaa accctttatc taactgttct aacgtctcca gtaaactcgt
     5281 tctttctcgg actttggttt ttccgctaat aatgtaacag tcatcaacct ctttctcttt
     5341 caataacttt tcaaagacat ctatctgttg aattcgatta actaaaacca agatattccg
     5401 tccttctgcc acttgggcta gaatatcctt gagaatcaac tgattcctcg ctgagtctgt
     5461 agcaatccaa tcactgagct gtataaaatt acttgctttg gtcttttcaa tctccaaatg
     5521 accaaaagaa gtgaatctta attgcaattg ccgtttaaaa tccgtttccc tcttatcagc
     5581 agtatggagt atctcaccaa ttctctgaaa aacaataggc tcatgaccat tcttacgctc
     5641 aggcgtagcc gtcaaaccgt aaagatactt ccctctaaac tgagcaacaa ctttttcaaa
     5701 catcaaggca gagacatgat gacactcatc cacaatcatc atctcatact catccaaaag
     5761 actttgacta ttttccaact taaatagaga ttgaatcata acgacatcaa ccagtttact
     5821 cagccatttc ttagtcccac cgtactgtcc aacatagccg attacctttt cacgacctga
     5881 tgccgtataa cggatagcct cctcctcttc gaaagtcaaa aagcagttta agcgatctag
     5941 ccattggtct aagagttgct tattatggac tagaataatt gtttttgttt tccgttcaga
     6001 gataagagca gcacctaaaa cggtcttccc aaaaccagtc tccgcatgaa gtaaaccatt
     6061 ttctttagaa gtcatatctg acagggctaa ctcttgctca aaagtgagtt ctcccttaaa
     6121 ttccacgcta atagaccttt gtacctttct cctatcttcc acaactacct gcttaaattt
     6181 atcttgcaat ggatacagca aacctcttgg caaccataaa taatgatcgg attctccaaa
     6241 taaatacatt ctctcaggaa tttgataggt tggctgtcgc atagcctgct ttaaataaaa
     6301 ttcgggatta gaaaatgaag ccatattttt caagaaaaac agtgtcttgg gtgtcacaga
     6361 cgatttttca agttggatca tattggataa gacgatcttc aaccccttgt ccaattcttg
     6421 cttgcctaac tcttcttgga ttaacagtgc cactttagca gttgaaaccc tctgaatttc
     6481 ttgtagatac ctccattggt cttcataagg ctgaaactgt tcatccacaa agaccgttcg
     6541 cccttgatgg taagcttctc cttgaaaagg caaggcaatc aaatttccaa atcccccctt
     6601 aggaaggaca tcctgatttg gaaacatgcg atcaaaagaa tcaaaggaca gttgcatact
     6661 ttcctgcatt gccagttcta tcagtttctt tccaaacaag cgagcctctc gactcggaat
     6721 cgcttcctca aagaagaacc aaatatggag tccgtgaccc gaacgagaaa tctctaaatg
     6781 ggcttccatc tggcgttccc tggctattct tcgaatggtt aaaccagctt ctttccaatc
     6841 tccttcatca aaatccagta ccaaaaaatg acagctatca tctaagtgca taggaaagat
     6901 accgatagct gtctccccac gaaaatgaga tttcaaaacg gagttcgtca atgtctggaa
     6961 actccgtttt tcaggtggca actgcttcca accataatca taggaaggaa aatactgaat
     7021 tttcccttgt tcattgataa aattcttagc ataaacatca taacgtccag caaacacgga
     7081 ggtaaacaat tgtaattttt cttgcgtcgt caagtgacta ctttgaagtt ggaacatctc
     7141 ctcgaaccga gagcgttcca taacaaactg actcttgtct ttaagacgtt tacacaagaa
     7201 aaactcacta tccccatcaa aagaagaaaa gacatcaagc acttctacca caattccatc
     7261 caaagacaca aaaacagcca taagagtcac ctccttgatt cctataggct gattataaca
     7321 agaatagctg aaattgtaca cgaaaataaa atccgaatag cactcatttt gtatgcgact
     7381 aatagtccat ctcgctccgg aatgtacgag gtaaatagag tttaaacgag cagtctataa
     7441 aattcaaaaa acgcatatta ccaaggttgt tttgaactac accccaaaag ttagacagaa
     7501 aaaatctaac tttttggggt gtttttatta tgaaattaac ttatgatgat aaagttcaga
     7561 tctatgaact tagaaaacaa ggatatatct tagagaagct ttcaaataaa tttgggataa
     7621 ataattctaa tcttaggtac atgattaaat tgattgatcg ttacggaata gagttcgtca
     7681 aaaaaggaaa aaatcgttac tattctcctg atttaaaaca agaaatgatt cataaagtct
     7741 gacatgaagg ctggactaaa gatagagttt ctcttgaata cggtctccca agtcgtacga
     7801 tacttcttaa ctggc
//
LOCUS       DAVKMJ010000069         7787 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000069 DAVKMJ010000000
VERSION     DAVKMJ010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7787
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.069"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(836..2056)
                     /gene="divIB"
                     /locus_tag="VW348_001976"
     CDS             complement(836..2056)
                     /gene="divIB"
                     /locus_tag="VW348_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEU9746827.1"
                     /translation="MSKDKKNEDKETLEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQKDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVIDMEAGVYSYTVADKLIMEAEEKAKKEAEEAEKRQEEERKRLEEEQKKQEE
                     ESNRNQTTQRSSRR"
     gene            complement(2066..3124)
                     /locus_tag="VW348_001977"
     CDS             complement(2066..3124)
                     /locus_tag="VW348_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEU9746828.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(3128..4480)
                     /locus_tag="VW348_001978"
     CDS             complement(3128..4480)
                     /locus_tag="VW348_001978"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEU9746829.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQTASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGLFEEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(4584..5225)
                     /locus_tag="VW348_001979"
     CDS             complement(4584..5225)
                     /locus_tag="VW348_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9746830.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(5227..7248)
                     /locus_tag="VW348_001980"
     CDS             complement(5227..7248)
                     /locus_tag="VW348_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU9746831.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLIDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(7319..7618)
                     /locus_tag="VW348_001981"
                     /pseudo
     CDS             complement(7319..7618)
                     /locus_tag="VW348_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
BASE COUNT         2332 a         1696 c         1326 g         2433 t
ORIGIN      
        1 ttaaaaatat ttatcttttt tcgtgatttc atagaatcta taagtcccat tttactaaga
       61 acaatataaa atcttaaata atatttcttc cctactaaca ctaataagtc cgatatggta
      121 aattcttgac ctattagttg ctctaaccat ttttttcctg tttcccaact aatacatgtt
      181 tcttactgga tggtatatat agatgatact gtccctcata aggagtaggt aatatcttaa
      241 tcttatcaac aattctcata acaaacctaa cctttaataa ataaaagagg ggctaagtaa
      301 aacatactct agtccctcag tccgcaatca ataaaataat gactaattct attaatctct
      361 tgctgcaaga ctaatacgga aaattcaaat gactgtctaa attgaaaaag cttgatatta
      421 gtaagtgaac aaacttcaac aaccagcaag agcaaggatt gctaaaccaa atccgatacc
      481 tgttgcaagt ccagctgaaa aatcactaac tggtactgaa atttcttcaa tttcctcaaa
      541 taaaaagtta tcttgcatga ttatcactcc ctatcttttt aacaacaggc tactccaatt
      601 aagagaacta ccccagttcc aagtaaaact cccccccaaa attcaccatc tgtaggggct
      661 acgatttctt caatttcttc aaataagaat acttcatctg acatatgtgt taccttcttc
      721 ataaaaaatt tttttgtaat cgattacatt gcaaatgtaa cataaagaaa aacagatgtc
      781 aaatattaaa cgtaaaaaca tggcaactaa agagctatag gagaaaaggt aaaacctagc
      841 gacgcgatga gcgctgggtc gtttggtttc gattgctctc ttcctcttgt tttttctgtt
      901 cttcttctaa acgtttacgt tcctcttcct gccttttctc agcttcttcg gcctcttttt
      961 tagctttttc ttctgcttcc ataatcaatt tatccgctac agtgtagctg tagactccag
     1021 cttccatgtc aatcacactc ggttctgaca attgtggctt aatcttactg taatatggca
     1081 gtttcttact catttcagat agaggaacca agacttcgtc cgaatcattc atggtcaatc
     1141 gaattaaatc ggatgtcacc ttgcttgggg ctaattccac cttttggata gccgccttga
     1201 gttctgggct aatttgagca agttctgaga caaaaacctt gatttgttca ctatcattaa
     1261 agagaactga taaataagtt tctggtaaac tgttcagact cacagaacta gtctcaagct
     1321 gaccactgga aagaatagga taatgatttt caccagaaat atagtaggcc acaatatcat
     1381 attccttgac cttaatagtg aacttagttg gaaattgata gacaagttga gctgattcaa
     1441 cccaatagtt agacttaatc tgcttttcat attttgcctt gtctagcaga aggttaatcg
     1501 tataatccga atcctgaatg cctgaagcct gtcgaatatc atcagctgta gtttgcaccg
     1561 ttccctcaac acgaatatct ttcatggtcg cataaggact gagcaagtag gcagagacaa
     1621 tcaataaaag cagacttgga aataaaatcg tgaaggctcg caagatatgg ataccaggaa
     1681 tctttgcttt ggctggtttt tcctttgtag cctttttagc aagcttttta tcctgttcct
     1741 ccttctcttt agactctggt tcttctttct cttctttctc tttgtcagcc tctgaggatg
     1801 ctactttttc ttcagactct tccttagctg attctgaatc tttctggtct gtttcactct
     1861 cctggtcctg tttatcctct gacttctcag attcttctcc cattcgagct tgtctttcct
     1921 tttccttctc ctcagctaga gccgcctctt cttcagcctt cttttttaga tattcttggt
     1981 ttcgtttctg ccattctgat aactctttca attcttcgag ggtttctttg tcctcatttt
     2041 tcttatcttt tgacatttac tttccttatg ataaatcttt tttcaacaat tgataaaaat
     2101 ctgctagaga tttcaattcc ttagaagctt tcatcttagc ttggtaatct tccttgtgac
     2161 ttagtaagtg agaaagcttc tcttccaaac tatccaaggt caaatcgctt tcttgaaggt
     2221 cttctgcata gcctttctta acaaagtaag ctgcattttc aatctggtca ccacgactag
     2281 cttcacgacc aagcggcaca atgacatgca attttgctat cgccaagagc tcaaaaatcg
     2341 tattggcacc accacgtgtc acaacaatat cagccaattc catcaagggt tgatagagat
     2401 cggtcacata gtcaacacga aaaagatttt ggctcaactc attcaggcta gaatctccag
     2461 ttagattgat aatattgtag cgctctgtta gttctttttt atggtctgtc accaattggt
     2521 taaagacacg agcacctgca gaaccgccaa caaacaatac agtcggcaat ttatgattaa
     2581 agtggctttg aatatccacc aattcatctg gttctggatt tttttgatct gaaaccttgg
     2641 tcactgctcc cacatgctca accttagcca aactcgaagc ttgttcaaag gttgaataca
     2701 tcttagtcgc aaatttatag gcgattttat tggccaagcc catagacagg tcagattcgt
     2761 gaataaagac aggcactcct gacacacgcg cagcgataac aggcggtact gagacaaagc
     2821 ccccctttga aaaaagggtc tgtggacgaa gtcgcaacat gataaagagc gattggacga
     2881 ttccccagcc aactttgaag acgtccagca tattttgcca agagaaatag cgacgcaatt
     2941 tcccagtcgc aatggagtgg aaagtgacat ccaaacctga cttaaggatt tcttggtgtt
     3001 cgataccacg cttgtccccg atatagtgga cttcccaacc atcttcgatg aacttgggca
     3061 ttaacaaaag attgagggta acgtgtccaa ccgtcccccc acctgtaaag acaatttttt
     3121 tcatatttta ttcttttaac tccgctactg tgtcgataaa gaggtcgcca cgtacttcaa
     3181 agttagcata catatcccag ctggcattgg caggactaag aagaaccaca tctccttgag
     3241 tcgcaagctc ataggccttg cgggtcgcat ctgcaatatc tgtcgcctcc acataagcga
     3301 caccagcctt gtctgctgcc cgtttgacac gttctgcaga ttgacccagg atgaccatct
     3361 tcttgagtcc agtaatatct ggcaccaatt cgtcaaactc attgccacgg tccaaaccac
     3421 ctgcaatcaa gacgaccttg ctgttgtcaa atcctgacaa ggctttttga gtagccaaga
     3481 tattagttga tttactgtcg ttatagaatt taacaccctt gatgtcatcc acaaactgga
     3541 gacggtgttt gacaccaccg aaggctgaaa gagtttcctt gatggtttga ttgtccacac
     3601 cacgaagctt ggctacagca atagtcgcaa gggcattttc cacattgtgg ctacctggaa
     3661 caccgatttc attcgctgcc atgactactt caccacggaa gtagagttga ccatcttcca
     3721 gataagctcc atcaaccttt tcaagtgttg aaaatggtac aacagtggct tctgtcttgg
     3781 aagtcaagtc ttttgccaag tcttgattaa agttcaagac aaggaaatca gctgctgtca
     3841 tcttgttctg gatattccac ttggctgcta catattcctc aaataatcca tgataatcga
     3901 tatgagttgg cataaggtta gtaataaccg caatctctgg atgaaattct tgaacaccca
     3961 tgagttggaa agaagaaagt tccataacaa gcgtgtcctt gtccgacgca gtttgggcca
     4021 cttgactagc tggatagccg atattccctg ataaaagacc atgttgccca gcagcagtca
     4081 aaacttcccc aatcatagtc gttgtggttg tcttaccgtt cgatcctgtg ataccaataa
     4141 tcggtgcttc tgaaatcaaa taagccaatt ccacctcagt caagactgga attcccttgg
     4201 ccaaagcctt ttcaatcatg ggattgttgt aggggatacc tggatttttc accataaggg
     4261 caaactcttc atccaagagt tccaaaggat ggccacctgt aatgaccttg atcccttctt
     4321 ccagcaaact ttgggcagct ggattgtcct cgaatggttt cccgtcattt actgtcacta
     4381 tggcgcctag cttatccaac aaacgagctg cagattcacc agacttggcc aaacctaaaa
     4441 caagaacttt cttattttta aattgatcta ttactttcat gtctcgaact ccatttctac
     4501 tcctactatt ttaccatttt tatggaaata aaaaagccac aaagtgtgtt tgtgactctt
     4561 tcttctaact gaatcttacc atattatcta tgtgataaat cggtaactcg aatgacctga
     4621 tccacttgct cccaaatcag aggattgtgg gtcgcaataa taatggtccg attcggattt
     4681 tttaaagatt ctaggatgga aagtaattcc tcagagtttt tggggtctaa ggaagcggtt
     4741 ggttcatctg caagaatcaa aggcggatcc tttaaaatta tcttcgctaa tgcaacacgt
     4801 tgtgcttctc ctcctgataa ctcaaatata ggttgcttca aatccaaata agagaggttt
     4861 acacggttta gagcttgttt catcaaagag attttctctt tttccttcaa ctttttacca
     4921 actaaaccca gattgagatt ctctttgacg gtttggcttt caattaagcc aaaatcttga
     4981 aataagtatc ccaagtaatc tctaaagaaa acagaaggct tgatgtcctt aagagaagtg
     5041 ccatcataga tgatttgccc tttgtcatat ggctctaatc gtccaatcat attcaagagt
     5101 gttgtcttac cacagccact tgtaccgatt aaggcataaa ttttcccacc ttcaaaatga
     5161 agatttgtat ctgaaaatag ctgacggctt ccaaattttt tagatatatt ctttagttca
     5221 atcatcctat tttcctttca taattgtcat agaaacacga gattctttct gcgcttgacg
     5281 gtaaagcgtc agaactgcac tagctagaaa gactaataaa gtgagcaagc caatcaccaa
     5341 gtctcgactg cttaaaataa agagactagc accaaataca aaactggcaa attgactaac
     5401 catatactga gcatgtgttt caaaaaatcg taaacctgaa attcgtttaa tcaaaatatc
     5461 tcggcggaat tgctcgaaat atagaagatt gacagaataa aatagtaaca aggaactagc
     5521 tatccccaca atagctccta agattaaagt tgctgtttca gtttgaactt cattataacg
     5581 agttagataa acacttcttc cttctttaag ataggatact tgctcataaa ttccagcttt
     5641 cttcaagagt tctagcccac tctcatatcc tttgataaag agttgttttc cagcattgat
     5701 agaccaacta gataaggata taaaactatc acctgtagaa gtcggcgtga atacaactaa
     5761 aatcggatca atcaaatact gagtggatac gggattctca ccgttattat aaacaaaccg
     5821 cttttctccc attgaaagat aactaacgtg cgctttcatc tcataatcca aaggagcact
     5881 tgcctcctca ccagattttc cataataact caatctttct tcaaaaactt tcttaagttc
     5941 tgcttctcga gagcgcaaat gttctgggag caagaggata aactcacctt tttggagatg
     6001 ggctaacttc tgtttggtct cagcatctac cacgaccttt tccttgtcca aataactggg
     6061 actaacatag agcgtattag catctggact ataggtatcc agtgtctctc cctgttcatt
     6121 ttttccttgt ggattggcaa aatggagcag attatccttt acataaagag cttgttcttc
     6181 ttcgattgct tccttggcaa aggcatacca cttgctctga ttttctgtat cttttcctct
     6241 atcacctaag ccaaaagaaa tttgataata gtctgctcta tcctgccatg cttgttttga
     6301 aatttcaagt tctttcaatc gttggtaaga cgtcaaacct gtcttaacag cgtatcctac
     6361 tgtaaagaca gcaaccaact gacacaatag ggttaaaatc atcaggcgtt taaggggtaa
     6421 tctcccctta ataacgggaa ctaatgcttt gtaattcaaa ctcattagat aaagaagcat
     6481 tagtaaaatt gaaatcgcca ataaaaacaa cagatagaaa ctaatcccaa aaccataggt
     6541 ggctaacaag ataggataaa acaaaccttg actaaaaaga acgactcccc cacctaggaa
     6601 ggaaaggagg gctgatagaa ggagccattt gatatcagta gataaagaat gccccatgat
     6661 ggataagaga gtctgaccag aaaagagttt tatacctgct gctctcattt ccttaatccg
     6721 agtgataatc actaaagcaa agaaagataa accaaatatt gctaaactaa ttaaaataag
     6781 gggatttagt aatattcgaa aagcaagaaa atagggcggt atctttcggt cagcacttgc
     6841 tttataaccc aaatctccta atttatcggc aagcttttct ttcgtcaagg agcctgacaa
     6901 aaggagataa ctatttagcg gatcactacg ttcacgactt tcttggctag cttcttggaa
     6961 ttcttttggt aaagttccct gaccataagt tgcataagta aagtgagtcg tcccatcctt
     7021 actcggctct acaattcttc tagctattaa actctgttct gagtttgcaa aattctccaa
     7081 ttcctgttca aatacctcac gcgtcggttc ctgagtatct tttttgacac gaagtaaaga
     7141 aacggaatca tagcttgcat ataaatattg tggcgcacgt aagacaataa tccaagcaag
     7201 gaagaagctg agaaaaaaag ttgataataa tatgaatagt ttcttcatag tagactcctt
     7261 gtaaacaaaa ttccccctgt aatttcttac aaggggaacg atttaaatca atgaacgatt
     7321 agtcataatc acagtaaaat gctacttgtt ctccccattt agtccaaatc catgcatagg
     7381 aggtttttcc agcaggagct tctcctttat cagaatgacc atcccatctg ctcacgatgg
     7441 atgaataatg atatttttta ccatgatagt aatttgaaaa agcctaacca cctcctgaac
     7501 cttctccata tgtccatact cctccatctg gatattgtac agcagctgat gcagctccca
     7561 ataatgtaaa atttgaaata agagctagag caagtaatct atgttttttc gttttcattt
     7621 tattttttct ttcaaaaaaa tcacaccttg agcaacaatg caacaaaata aatcctcctc
     7681 tctcttttgt tgaaatcgct ttcttatgtg ataagaataa catttttatt atttgttgtc
     7741 aaggaaaaaa tcgaattttt tagatgtttt actatattat ctctatg
//
LOCUS       DAVKMJ010000070         7645 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000070 DAVKMJ010000000
VERSION     DAVKMJ010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7645
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.070"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(1..846)
                     /locus_tag="VW348_001982"
     CDS             complement(1..846)
                     /locus_tag="VW348_001982"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEU9746832.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKACAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            1102..2129
                     /locus_tag="VW348_001983"
                     /pseudo
     CDS             1102..2129
                     /locus_tag="VW348_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(2430..4319)
                     /locus_tag="VW348_001984"
     CDS             complement(2430..4319)
                     /locus_tag="VW348_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEU9746833.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGTEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKEQSKQLLTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFERDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLLGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            4457..6022
                     /locus_tag="VW348_001985"
     CDS             4457..6022
                     /locus_tag="VW348_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEU9746834.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYANAKSLDDFNGAKITSQQGVYLYD
                     LIAQITGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMVQVEPGF
                     KTGEEDTAIAIGLRKDDTRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTITGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWILNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            6022..6762
                     /locus_tag="VW348_001986"
     CDS             6022..6762
                     /locus_tag="VW348_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEU9746835.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(6871..7086)
                     /locus_tag="VW348_001987"
     CDS             complement(6871..7086)
                     /locus_tag="VW348_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746836.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
BASE COUNT         2417 a         1703 c         1355 g         2170 t
ORIGIN      
        1 ttatacaaat aaacggacaa aactgtaaag tagcaaaaca ctaccaagca cgatacggta
       61 tttaccaaaa agggtgaagt cgtgtttttt cacatagctg gtcaagaagc gaatagccac
      121 catgctgacc gcaaaagcta ctcccatcgc gaccaagagc aaaaacaatt gcccaaagct
      181 caagagttct ccggctttca caaatttgaa aatctttaag gcactagctc caaacataac
      241 gggaatccca agatagaagg taaattctgt cacaactgaa cgactggttc catttaacaa
      301 accaccgaca atcgttgcac ctgaacggct agtccctggt aaaagagcaa gaacttggaa
      361 gagtccgata tagaaagcgg tcgtataagg aagcttgtcc aactctgtta cacttggctc
      421 gatagcacac gctttattgc gcttttccaa atagatgaag gcaaccccgt agataatcaa
      481 catgagagca actgaaacca tgttatggaa gtgggtatca aaccaatcat caaatttaaa
      541 gacaccaagt aaaggtaaag tagcaatcaa gaccttcaac catagtctcc aagtcttacg
      601 aacttcctgt ttgtccttag tcggtttaaa aggattgagc ttgttaaaat aaatcaccat
      661 aactgctaaa atagcaccaa gctgaatcac gacattaaac atggacataa aggcttcatt
      721 ttgattttgg tattggataa actcctctgc taaaatcaag tgacctgtac tggaaatcgg
      781 caaccattcc gtaattcctt caacaatccc gaagaagata gattttaaaa tttcaataag
      841 atacatatat ttctccttat attatattta acgcagttag ctactgccaa agcccaagtg
      901 gtatacttgg aataagccac tgtggattag ttcatttcct ccaatcgctt gacgatttcc
      961 gaaaggatct aaccacagct ttttgtttca attggtaatg agtttgataa cgcatagacg
     1021 ttttatctcg tctaaggtaa caaggcaaaa agttcgtgga taaccaagta gacttgaaat
     1081 actatatctg gaggtactcc catgctttat gtgggcattg atgtcgctaa aaataaacac
     1141 gatgttacag ccttgaatgt tcgaggaaaa ctgttcttaa accactcact ttttcaaata
     1201 ataaagctgg ttttgaacta ttagatctgt ctcttcgaca gctcaaccaa gactgtctca
     1261 tcgctcttga agataccgga cattatgcct ttaatctact gaacttcctg catgaacaag
     1321 gatataaagt ttacacctac actcctttgc tcatcaagga atttgccaaa tcattatcac
     1381 ttcgcaagac taaaacggat aagaaagacg ctcatggcat cgctcttaaa cttctttctg
     1441 accccaatcg tgaacaattt caacacgata atcggcaagt agaactaaaa atactggcta
     1501 gacatattca tcgtctcaag aaaaaacagt ctgattggaa agtacaatac actcgttgtc
     1561 ttgatatcat ctttcctgag ttggataaaa tcgttggaaa gcattcagaa tatacctacc
     1621 aactcttgac atgctaccct aatcctcaga aaaggcttga ggcaggattt gataagctga
     1681 tagaaattaa gcgattgacc gcttctaaaa ttcaggatat cctctcagtc gcacctcgtt
     1741 ctatcggaac aacatctcct gctcgtgaat tcgaaatcat cgaaaacatc aaacattaca
     1801 agaggctcat tgacaaggcg gaaaaatgtg tcaatgactt gatggctgag ttcaactcgg
     1861 tcatcacgac ggttactggg attgggaatc gtttaggggc ggtcatttta gccgagattc
     1921 aaaatattca tgcctttgat aatcctgctc aattacaagc tttcgctgga ctggattctt
     1981 ctatttatca gtcaggtcag attgatttag ctggaagaat ggtcaaacgg ggttctcctc
     2041 atctgcggtg ggcactcata caagctgcca aagcatgcgc tcgcttttca cctgctttta
     2101 aggcctatct taagactaag ttagaataag aaaaacatta caatgtagcc atcatccacc
     2161 ttgcaaaaaa acttatccga accctgtttt atatcctaaa aaagagctgc catttgacga
     2221 acaaaaagtg atgtaatttc tgaaatcaac acaggattac ctttgaaaaa atggactttt
     2281 tcaagggctt tttgccgtgc tctaaaatca tcgccaaatc atcaaattga aataagaaat
     2341 agtttagata aaattattga cttttcttat agtttgtctt tcttctatct tccattatat
     2401 catacttttt cagtctatgg tagctctctt taaaaggctc cgatactgcc gccacctccg
     2461 cctccagaga agccaccgcc agaacttcca cttccagaag atacggagta ggtacttgct
     2521 gtatttgcga cactagcata atggctcatt tgcgcgcttg aatgataaaa catactgtgc
     2581 cagccataag ctacatagag attgatatct ggattttcaa cttgaatctg atgaaccttc
     2641 atcaaatgac taaccttgtc cgcatagcca agtaaggttg catagaccaa gagacgattc
     2701 caaacaacaa tactttccaa ttcagcctta tccagtcgtg caatctcacg taacatattt
     2761 tcaaaactgg tccagagata gtagacctca gctcccgctt catttagaac accatcacga
     2821 ttatctagtc gaagcttcca ataatagaaa acagacaaaa ctaaccctag aaaaccaagt
     2881 attggcaaag ggaggtaaag atagccatga acgtctaaac tgtacaagaa caaaccaaat
     2941 ccgataaata ggggcaggat agtcaaggca cccataccca cttgcaaggc cttttcccca
     3001 ccagttaaag gacgataata atctgggagc ccccagaagg aaactcgttt tctcactcct
     3061 tcttgcatct ggttcaatac ctcttcaaaa gaagatttga gttgaagccc tcttgcttga
     3121 atccgttttt catcagaaac tttggctcta cgataaagac tatcagatac cttgtaatcc
     3181 gcaaacaaat tggaaagagt ttcttctttt ttacctgaaa aggctagatt tagacagtct
     3241 ctctcaaagc ttgacaaacc atcttctttt actagcctca aaccaactgc atctccttct
     3301 gaaatgatag agacattccc acggtctatc acatctagca aggtagcttg aataagttga
     3361 tcaaaggtga attttccagc tcccttgacc aagggactca cttcctccaa ggaggtcgag
     3421 tagactgctt ctgataaaac cataggctct aattccattg gtggttcata gagacgatga
     3481 tttttggcat atttgactga aggagtggtc tttcttctat aaataaaata gaagcagaca
     3541 ctcaataaca aggagatgga aaggatcgaa gggaggaccc aagtaagtag ttgtttactt
     3601 tgctcttttt ctctaacaat cgagtcttct atcttattaa actcttctaa tcgattccct
     3661 ttcaatccct gatccctagc gctagcaaaa tcggtccgag gccaataggc atgcaactca
     3721 actccacgct tagccggaag attgtctaaa cggatagtat aatcaaggtt actcttttca
     3781 atcgttccct ctctaaaaag tttccctgta tggaaaaaga gtttttcagt ccccttgtct
     3841 ccccttacat gaaattcaaa cttttcaata gactctgaac tatctgtcag aggttgccaa
     3901 tttaattcag cgatatcatc ataaaggaaa agtaaatttt ttaagttcca gacgaggtca
     3961 acttcaacta tgtcgccctc ctgacctgga ttatagactc tcacagtata accatccgct
     4021 tcttctgtta cttcgctagt cacatctgct agttctgcac cgtttttcgc ggcctgaatc
     4081 tttggatgag ggtcaatgtc aaacccgcta ggcatcttac cagcacgtcc aagtcccacg
     4141 atttggccct taaagtcctc ctcaaactgg taaactatct tctgtctaaa ctctgccgta
     4201 ttatctgcat gaatatacaa atccccttga taagagttta tcttgaaatc aatggcaaaa
     4261 acagagagtg gaagaaggca aaacaagcct aacaccagta agaaaaaagt ttttttcatc
     4321 aactaagccc cctttttatc tttcttatca ttatagcatt ttttcgtaag taaaggctta
     4381 cttatgttga aaaattacgc atttttcgat aaaataggag acagttattt tttaatagat
     4441 cagaatagga gaaatcatga gaaaaatata cttatctatt ttcacaagtc tcttgctgat
     4501 gctaggactt gtcaatgttg ctcaagccga tgaatattta cgcatcggga tggaagcagc
     4561 atatgctccc tttaactgga cccaggatga tgatagcaac ggagctgtca aaatcgatgg
     4621 gaccaatcag tatgccaacg gatacgatgt tcaaatcgcc aagaaaatcg ctaaggactt
     4681 aggtaaagaa cctttggttg ttaaaaccaa gtgggaaggt ctagtccctg cccttacttc
     4741 tggtaagatt gacatgatta tcgcaggtat gagtccaact gcagaacgca aacaagaaat
     4801 tgccttttcg agcagttact acactagcga accagttcta ctggtcaaaa aagattctgc
     4861 ctatgcaaat gctaaatctt tggatgactt taatggtgcg aaaatcactt ctcaacaagg
     4921 tgtctacctt tatgacttga ttgcacaaat cacaggtgct aaaaaagaaa cagccatggg
     4981 agacttcgct caaatgcgcc aagctcttga ggctggtgtc atcgacgcct atgtttctga
     5041 acgcccagaa gctctgactg ccgaagccgc taactctaag ttcaagatgg tccaagtaga
     5101 accaggtttc aaaactgggg aagaagatac agctatcgcc attggacttc gtaaagatga
     5161 cactcgtatt agccaaatca atgccagcat tgaaaccatt tcaaaggacg accaagttgc
     5221 cctgatggat cgtatgatca aggaacaacc tgccgaagct acaacaactg aagagactag
     5281 cagtagtttc tttagccaag ttgctaaaat tctttctgaa aactggcaac aactcttgcg
     5341 tggtgctggt atcactcttt taatctctat cgtcggaacc atcacaggtc tcattattgg
     5401 acttgccatt ggtgttttcc gtactgctcc tctctctgaa aacaaagcca tttacggcct
     5461 acaaaaacta gtcggctgga ttctcaacgt ctacattgaa attttccgtg gtacgccaat
     5521 gattgttcaa tcgatggtta tctactatgg aactgcccaa gctttcggga tcaaccttga
     5581 ccgtacactg gctgctatct tcatcgtttc aatcaatacc ggtgcctaca tgactgaaat
     5641 cgtccgtggt ggtatcctag cagttgacaa gggacaattt gaagctgcga ctgctcttgg
     5701 tatgacccat aaccagacca tgcgtaagat tgtcctacct caggtagtcc gtaacatcct
     5761 acctgcaact ggtaatgaat ttgtcatcaa tatcaaagat acatctgtat tgaacgttat
     5821 ctctgttgtc gaactttatt tctcaggaaa taccgtggca acacaaacct atcaatactt
     5881 ccagacattt acaatcatcg ccgtgattta ctttgtcctc accttcaccg taacacgtat
     5941 cctacgattt atcgagcgcc gaatggacat ggatacctat actacaggtg ctaaccaaat
     6001 gcaaacggag gatttgaaat aatgacacaa gcaatccttg aaattaaaca cctcaaaaaa
     6061 tcctatggac aaaacgaagt gctaaaagac atttcactca ctgtccacaa gggagaggtc
     6121 atctctatca tcggaagctc tggaagcgga aaatcgacct tcctacgctc cattaaccta
     6181 cttgaaacac caactgatgg acaaatcctt tatcatggac aaaacgtcct cgaaaaaggc
     6241 tatgacctca cgcaataccg tgaaaagttg gggatggttt tccaatcctt taacctcttt
     6301 gaaaatctca atgttcttga aaacacaatc gtcgctcaga caactgtcct aaaacgcgaa
     6361 cgcacagaag ctgaaaagat tgccaaagaa aacctggaaa aggtcggcat gggagaacgc
     6421 tactggcaag ccaaaccaaa acaactctca ggtggtcaaa aacaacgtgt ggccatcgct
     6481 cgtgccctct ccatgaatcc ggacgctatt ctctttgatg aaccaacatc agctctcgat
     6541 ccagaaatgg ttggagaagt cctcaaaatc atgcaggacc tggctcagga aggcttgacc
     6601 atgattgtcg taacccatga aatggaattt gcccgtgatg tctctcaccg tgttatcttt
     6661 atggataagg gcgtgatcgc tgaagaaggt aaaccagaag acctcttcac caatcctaaa
     6721 gaagaccgaa caaaagagtt ccttcaacgc tatctcaaat aaaaagaaaa ggctgcatca
     6781 accgtgcagt ctttttgctg tcctcaaaat gaaaaggcag attctctatc tctactactt
     6841 gaaggtcaag aatccgccgt tatccaaaga ttaatcttca aatttttcat aatttttttc
     6901 atagaaatca attaggccta gggctgtttc aaatgaaata ttttttactt ttgcacgacc
     6961 ctgcgccaga gcaatgatag acatttcacg cgcattcgtt tctttagaga tacggtagcc
     7021 tgtgattttc ttatcacgaa cccagccaac aactgattct actttttcaa agtttgactt
     7081 agccatgttt ttctcctatt ttcttcttta taatatttaa ttgtatacgt ttttactact
     7141 tttgtcaata aaaaaacatg tattcaacga aaataattag ttcagaattt tagcttcaga
     7201 attttcttac ttcctttttg aatccgataa tatataggtt ttactagtct ctacaccata
     7261 aatatttgct aataaaaata ctgtattatt accctcttaa ggtgcgaaat tattcaagtt
     7321 cttaaaaaat gcttctctat ttccgtaaga tagcttattt cttcgattta agaactgaag
     7381 atgatagttc taacctttag aaatccaagc cttcactagc tcaaaaactc ctatctttct
     7441 tcctcaataa atcatctgag agataggtat tccttatgtc cttcaaattc atcactcctt
     7501 tggatattga ggtgctagcc tagaagcaga cacccgatta tctaaaccat ccttaataaa
     7561 gatgacaaga cagataagct cagttaatta cttatatatc tttttaatat ggtatatttg
     7621 tcaacaaaaa gaaatcaaat catac
//
LOCUS       DAVKMJ010000071         7329 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000071 DAVKMJ010000000
VERSION     DAVKMJ010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7329
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.071"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(82..504)
                     /gene="nusB"
                     /locus_tag="VW348_001988"
     CDS             complement(82..504)
                     /gene="nusB"
                     /locus_tag="VW348_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEU9746837.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREYT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(497..886)
                     /locus_tag="VW348_001989"
     CDS             complement(497..886)
                     /locus_tag="VW348_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU9746838.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            complement(908..1468)
                     /gene="efp"
                     /locus_tag="VW348_001990"
     CDS             complement(908..1468)
                     /gene="efp"
                     /locus_tag="VW348_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEU9746839.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            complement(1597..3039)
                     /gene="gatB"
                     /locus_tag="VW348_001991"
     CDS             complement(1597..3039)
                     /gene="gatB"
                     /locus_tag="VW348_001991"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEU9746840.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            complement(3039..4505)
                     /gene="gatA"
                     /locus_tag="VW348_001992"
     CDS             complement(3039..4505)
                     /gene="gatA"
                     /locus_tag="VW348_001992"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEU9746841.1"
                     /translation="MTFNDKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDTDNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSASVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILSAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            complement(4505..4807)
                     /gene="gatC"
                     /locus_tag="VW348_001993"
     CDS             complement(4505..4807)
                     /gene="gatC"
                     /locus_tag="VW348_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEU9746842.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEKDNYYIKVPAILDDGGDA"
     gene            5020..6564
                     /locus_tag="VW348_001994"
     CDS             5020..6564
                     /locus_tag="VW348_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEU9746843.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            6819..7016
                     /locus_tag="VW348_001995"
     CDS             6819..7016
                     /locus_tag="VW348_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEU9746844.1"
                     /translation="MKEEKKAIVLGADNAYMDKVETTIKSLCVHHYNLKFYVFNDDLP
                     REWFQLMEKRLETLNSEIVNV"
     gene            7127..7303
                     /locus_tag="VW348_001996"
     CDS             7127..7303
                     /locus_tag="VW348_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEU9746845.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
BASE COUNT         2036 a         1442 c         1702 g         2149 t
ORIGIN      
        1 tgaacatcaa aaaagaaagg acgaaatttg tcctttctcg agcttagctt ttcttcaacc
       61 cactacagtt gacaaagagc cttattgttc ttctgttaca aactggctga gcagtccatt
      121 gataaaacgg gcagattttt gatcggagaa gtcctttgca agctcgatag cttcattaac
      181 agcaaccagc tgaggagtgt caaatgaagt gatttcaaag actcccaagc gaaggaggtt
      241 tctctccacg agcgttaagc gttcaatggt ccaacctgct tttaaatgct gagtgatttg
      301 cttatctagt tcttcctttt tagcttgaac accagaaacg aggtctatca aaaaggctgg
      361 aagttgtaca tccgtatatt cacgatcatg agtataggcg aaacgacaag cagtttcgac
      421 atccgtaccg aactcaaggc tcatgagagc ttgaaaagcg catttacgga gttggcgtct
      481 agattctaat agtggactag tcattgagga agtcctcgtc aaatagatct ttcaattctg
      541 gttttggtgt tttatctggg acgatacctg caacgtgaat attgatagca gcgagttcta
      601 catcagccat attacggacg gcatctttga cagctttctg gatagcaacc gctaccttag
      661 gaacttttac tccgtactca aggtagagat agatatctgc tgtgagttct tcgtccacgt
      721 ttttaagata aatgccacgg ccgagtgaaa gttttgaaag ggtatcagac actgatctgt
      781 ttgaaaaaga gtgaacaccc tctacctttg cagtagcgat agcaatgatt ttttcaagta
      841 cacgtggggc gataacgatt tcgccaagtt gttcttcaat tcccatagaa tgacctcttt
      901 ctagagatta ggcacgagaa acgtaagttc cttctgcagt gttgataacg agtttttgtc
      961 ctgcttcgat gaagtctgga acgtttacga caagtccagt ttccatcgtt gctggtttac
     1021 cagaacctgt aacagtagca cctttgatag atggttgagt ttcagcaact gtcaactcaa
     1081 cagtagtagg aacggtgaca ccgatcactt cagttccgta gaattggatt ttcacatcag
     1141 agttttcaag gatgtaaagc aattcgtttt caacattgac tacagggatt tcgtattggt
     1201 cgtaagtttc tgtattcatg aagtatgctg tgtcatccat tttgtacaag tattgagctg
     1261 ggacagtctc gataatagct tgttcaaatt tttcctctgg acggtagctt gtgtcaaatg
     1321 tagaaccagt acggacatca cgcaatttca tacgcatgat cgtgtttcct ttacctggtt
     1381 tgtggtgact agcttccaaa acgcgaatca atttgccgtc agctgtttca aaggtcatac
     1441 cagcttttaa tttacttgct tcaatcatgt ttttacctct ttaataaata ttattactct
     1501 tcattttacc ataaaatact ctggaaataa agccaaaata gttattggga gttggtagag
     1561 aagaaaaaac caaccttagg gctggttttg ttctgtctag ttttctttca acttcgccaa
     1621 ttcctgtgca agtagtttaa gggcaacttg tgggttggct tggcctttgg ttgccttcat
     1681 aaggaatcct gtaaaggcct tgtcggcgtt acgtttgcct gacttgaagt cggcaacagc
     1741 agcttcgtta tcggcaaaga cttggtggat gattgggatc aagatagctg gatctgaaat
     1801 ttgaaccata cctgcttttt ccacgtattc acgcgcgcca ccgccatttt tagctagatg
     1861 gacaaagact ttcttggcaa tcttagatga aatagtaccg tcttcgatga tggtaatcat
     1921 ttcaaccaag ttttctggtg tcaattcgat ttgttccagt gttttacctt cagcattcaa
     1981 gaactgagcg acttcccctt ggagccagtt agagacttgt ttggcatcac cacctagggc
     2041 aacagctttt tcaaagaagt cagaagtgac tttattagca gtcaactgac tagcatcgta
     2101 gtctgataaa ccaaggtcag atacataacg cgcacgacgt tcttttggaa actctggcaa
     2161 ctcagtccgc atttcctcaa tccactcgtc agaaatttca aagaggggta ggtctggttc
     2221 tgggaagtag cggtagtcag cagccccttc cttgacacgc atgaggatgg ttgttttgtt
     2281 agcttcatcg taacggcgtg tttcttggcg gatttgacca cctgagcgaa gaatttcagc
     2341 ctggcgttgg acttcgtatt caagaccttt acgaacgttt gagaaggagt tgaggttctt
     2401 caattcagtc ttggtaccga atttttcttg accataagga cgaagggaga tgttggcatc
     2461 cacacgcata gaaccttctt ccatcttaac gtcagaaatg ccagcgtact ggataacttc
     2521 cttgagggct gtcagataag cataggcttc ttcaggagaa cgcatatctg cctcagatac
     2581 aatctcaatc aagggaaccc cttggcggtt gaggtcaaca taagagtagc catctgtacc
     2641 atgggtgttt ttaccagcgt cttcctctaa gtgggcacgt tcgataccga ttttcttggt
     2701 cgtaccgtct tctagtttga cttcaatcca gccattatat ccgattggtt catcaaattg
     2761 agaaatttgg taggctttgg ggttatcagg atagaagtag ttcttgcggt caaagtgcat
     2821 ctttttgtgg atgtccatgt tgagggcaag agcagccttg ataccggcat caacaacccc
     2881 tttattgaga actggtagaa ctcctgggaa agaccagtca attacgttag tgttggcatt
     2941 ttggtcattt ccgaagtggg cagaagtagg tgagaagatt tttgaattgg tgttgagctc
     3001 tacgtggact tcaagtccga tgactgtttc aaagttcatt agttgtcacc tccaaaaatc
     3061 acgggttgtt gtttgtggta gtctgttgtt gcttcaaaag cagcagcagc ttggtaaatg
     3121 gtttcctcag agtacttggg accaatcaat tggagtccga caggtagacc ttgagagaat
     3181 ccagcaggaa tcgaaattcc aggcagtcct gccaagttta caggtatggt caagaggtcg
     3241 gctaagtaca tggcaactgg gtcatggttg agagaatcca agtcataggc aacacttgga
     3301 gcagttggac ccaaaatcaa atcgtaatcc gcgaagactt tttcgaaatc ttgaatgata
     3361 agtgtacgga cctgtccagc cttcttgtag taggcatcgt agtaacctga tgaaagactg
     3421 aaagtaccca gcatgatacg acgttttacc tcttcaccaa aaccttggct tcggctgttt
     3481 acatagattt catcaaggtt ggttgcatct tctgcgcgat agccgtaacg gataccgtca
     3541 aagcgttgca agtttgatga agcttctgat gaagcgatga tgtagtatac ggcaactccg
     3601 tatttagagt gaggaaggct gacttcttcg acaatagcac caagtttttc aaagtgttta
     3661 gcggcactta gaatggtttc cttaacctct gggttaattc cttcaccgag gtattcctta
     3721 ggcaaagcga ttttcatacc cttgatgtct tggccgattt ttgaagtaaa gtcggcgatg
     3781 cggacagaag cagaagtaga gtctttagca tcttcgctgg caatagcgtt gagcaagagg
     3841 gcattttcct taacagtagg agcaaaaggt ccaatctggt ctaatgagct gccaaaggca
     3901 atgagaccga aacgtgaaac tgttccgtag gttggtttga gaccaacgat tccgttgaag
     3961 gcagcaggtt ggcggatgga accaccagta tcagaaccaa gtgacaagcg aacttgtcct
     4021 gaggctacag ctgcggcaga accacttgat gacccaccag gaaccttgct gtggtcccaa
     4081 gcgtttttag ttgctccgta gtgtgaagtt tcacctgaac cacccatagc aaattcgtcc
     4141 atgttggtct ttccaacgac aatcatgccc ttggtttttg cattggcaac agctgtcgca
     4201 tcaaagattg gctcatagtt gtagagcatt tttgaggcag cagttgtgag aataccgtct
     4261 gtagagatgt tatccttaac agcaagtgga attcctgaaa ggacattgtc agtatcaatt
     4321 ccagcttcat caatggcttt agcttgaaca agagcttgct cctcagcgat ggtgacaaat
     4381 gaattgaggg cttcctcacg agacttgata ttttcaagtg ttgcttgggt caattctgtt
     4441 gcagaaattt ccttagagac aaggagattg tgcaactctt caatagtttt atcgttaaaa
     4501 gtcattaggc atctcctcca tcgtctagga tagctggcac cttgatatag tagttgtctt
     4561 tttcaggtac gtttttaaac aagcgatcac ggtctgttcc ttcttcggcc acatcagggc
     4621 ggagtacagt cttgcggtca gccatagtcg tagtaggtgc gacaccagtt gtgtcaactt
     4681 cgcccagcaa ttcaaccatg tcaacaatct tagacaaggt ggtcgcaaag gcagcagttt
     4741 cttcttcaga gaatcttaat tttgaaagat tggcaacgtg tgttacctct tcttgcgtaa
     4801 ttttcatctt gcatcctttc gtgaaatgat gatttttagt ctgttctatt ttaccatatt
     4861 ttcctataaa taagggaggg ggaagtgaaa agaaatagaa attgaaaaaa atgctaaaat
     4921 ccgatataat ggagtgttga aaggaatggt aaaatccaat gtaaaaatca ttctcagcta
     4981 ttgaaacaag aaaaatagag aatcaaagaa agagaactta tgaatattca agaagaaatt
     5041 aagaaacgtc gtacctttgc cattatctcc cacccggacg cggggaaaac aaccatcact
     5101 gagcagttac tctactttgg gggtgagatt cgtgaggctg gtacggtaaa agggaagaaa
     5161 acagggactt ttgctaaatc tgactggatg gatatcgaga agcaacgtgg gatttctgtt
     5221 acttcatctg ttatgcaatt tgactacgac ggcaagcgcg tgaatatctt agacacgcca
     5281 gggcacgagg acttctcaga agatacctat cgtaccttga tggcggtgga tgctgcggtc
     5341 atggtcgtgg actctgccaa ggggatcgag gctcaaacca agaaattgtt tgaggttgtg
     5401 aaacatcgtg gcattccagt ctttaccttt atgaacaagc tggaccgtga cggtcgtgag
     5461 cctttggatc tcttgcaaga attggaagaa atcttgggca ttgctagcta ccctatgaac
     5521 tggcctatcg ggatggggaa agcctttgag ggcttgtatg acctctataa ccaacgttta
     5581 gagctttata aaggggatga gcgttttgcc agtctagaag acggggacaa actctttggt
     5641 agcaatcctt tctacgagca agtcaaggat gacattgagc ttttaaatga agctgggaat
     5701 gagttttcag aggaagctat tctggctgga gaattgacgc ctgtcttttt cggttcagcc
     5761 ctgacaaact ttggtgtgca gaccttcctt gaaatcttcc tcaagtttgc tccagaacca
     5821 catggtcaca agaaaacaga cggtgaaatt gtggatcctt atgacaagga tttctcaggc
     5881 tttgtcttta aaatccaagc caacatggat cctcgtcacc gtgaccgtat tgcctttgtc
     5941 cgtatcgtat caggcgaatt tgagcgcggc atgagtgtca atctccctcg tactggtaag
     6001 ggggctaaac tatctaatgt tacccagttt atggcggaga gtcgtgagaa tgtgaccaat
     6061 gccgtggcag gtgatattat cggggtttac gataccggta cttatcaggt tggggatacc
     6121 ttgacggttg gaaaaaacaa gtttgaattt gaaccactgc caacctttac tcctgaaatt
     6181 ttcatgaaag tttctgctaa gaatgttatg aagcaaaaat ccttccacaa ggggattgag
     6241 caattggtgc aagaaggagc cgttcagctt tataagaatt accaaacagg tgagtacatg
     6301 ctgggagctg ttggtcaact ccagtttgaa gtctttaaac accgtatgga aggcgaatac
     6361 aatgcggaag tggtcatgag cccaatgggt aaaaagaccg ttcgttggat caagcctgag
     6421 gacttggatg aacggatgtc gtcaagtcgc aatatcttag ccaaagaccg ttttgaccaa
     6481 ccagtctttc tctttgaaaa tgactttgcc ctccgctggt ttgcggacaa gtatccagac
     6541 gtagagttag aggagaagat gtgactcagt accaacaatt ggaactaaag ttccaaattg
     6601 ttggacgcta gtcgctattt ggcgaactag ctaactgcct cactaactac gtttggcaaa
     6661 tgaaatcgat ttgtaaaact ccgtgtcgta atgtaaaaat tgtaaaccgt aatgggactt
     6721 catctaaaat ctccactggt atggttttac gaacgaatag gcgaaaataa tggttacgta
     6781 gaaacatatg atgggaataa aaagaaatga gataaaaagt gaaagaagag aaaaaagcga
     6841 ttgtcttagg tgcagataat gcttatatgg ataaagttga aacaacaata aaatctcttt
     6901 gtgttcatca ttataatctt aagttttatg tttttaatga tgaccttccg cgagaatggt
     6961 tccaattgat ggaaaaaaga ctagagactt tgaatagtga gattgtgaat gtttagattg
     7021 acagtaatat tctgaaaggt tatcgtctcc cctttgaggg actttcatat gcggcttttt
     7081 taggtatttt attccaaagt atgtaagcga gtctcgtgta ctgtatttgg attcagatat
     7141 tgttgtaaga aaatcgatag atgagctgtg ggatttggac ttgacggcta tacccttagc
     7201 tgcagttaga gatgattttt atacacataa ttttaattct ggtgttctgt taatcaacga
     7261 tggcatgtgg agagcagaaa atgtcacgca agacctgatt taagacacaa ataaaaaatc
     7321 ttccaattc
//
LOCUS       DAVKMJ010000072         7156 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000072 DAVKMJ010000000
VERSION     DAVKMJ010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7156
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.072"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..177
                     /locus_tag="VW348_001997"
     CDS             <1..177
                     /locus_tag="VW348_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746846.1"
                     /translation="AEALLEKVTDSSIRQNAVETLTGLKSSLLLGTKDNNTISAEVDS
                     LLALLKESQPTPIQ"
     gene            387..3506
                     /gene="phtE"
                     /locus_tag="VW348_001998"
     CDS             387..3506
                     /gene="phtE"
                     /locus_tag="VW348_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEU9746847.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQISQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLKEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            3732..4292
                     /locus_tag="VW348_001999"
                     /pseudo
     CDS             3732..4292
                     /locus_tag="VW348_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            4397..4745
                     /locus_tag="VW348_002000"
                     /pseudo
     CDS             4397..4745
                     /locus_tag="VW348_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(5016..5237)
                     /locus_tag="VW348_002001"
     CDS             complement(5016..5237)
                     /locus_tag="VW348_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746848.1"
                     /translation="MDLFQELICLVQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            5202..5831
                     /locus_tag="VW348_002002"
     CDS             5202..5831
                     /locus_tag="VW348_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746849.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSANSKDKTALLESTKAILVLNHQIQSKVSASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            complement(5867..7090)
                     /gene="pepT"
                     /locus_tag="VW348_002003"
     CDS             complement(5867..7090)
                     /gene="pepT"
                     /locus_tag="VW348_002003"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEU9746850.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
BASE COUNT         2548 a         1250 c         1370 g         1988 t
ORIGIN      
        1 gcggaggcct tgctagaaaa agtaacagat tctagtatta gacaaaatgc tgtggagaca
       61 ttgactggtc taaaaagtag tcttcttctc ggaacgaaag ataataacac tatttcagca
      121 gaagtagata gtctcttggc tttgttaaaa gaaagtcaac cgactcctat acagtagtaa
      181 aatgaatgga gcatatttta tggagaagta acctttcgtg ttacttctct tttttagaaa
      241 aacgtaacag aaacttgaca aaagtaattt taaatagtaa actatttact ggttaattaa
      301 atggttaaat aaccggttta gaaaactatt taataaagta aaagaagttg agaaaaaact
      361 tcatcattta ttgaaatgag ggatttatga aattcagtaa aaaatatata gcagctggat
      421 cagctgttat cgtatccttg agtctatgtg cctatgcact aaaccagcat cgttcgcagg
      481 aaaataagga caataatcgt gtctcttatg tagatggcag ccagtcaagt cagaaaagtg
      541 aaaacttgac accagaccag attagccaga aagaaggaat tcaggccgag caaattgtaa
      601 tcaaaattac agatcagggc tatgtaacgt cacacggtga ccactatcat tactataatg
      661 ggaaagttcc ttatgatgcc ctctttagtg aagaactctt gatgaaggat ccaaactatc
      721 aacttaaaga cgctgatatt gtcaatgaag tcaagggtgg ttatatcatc aaggtcgatg
      781 gaaaatatta tgtctacctg aaagatgcag ctcatgctga taatgttcga actaaagatg
      841 aaatcaatcg tcaaaaacaa gaacatgtca aagataatga gaaggttaac tctaatgttg
      901 ctgtagcaag gtctcaggga cgatatacga caaatgatgg ttatgtcttt aatccagctg
      961 atattatcga agatacgggt aatgcttata tcgttcctca tggaggtcac tatcactaca
     1021 ttcccaaaag cgatttatct gctagtgaat tagcagcagc taaagcacat ctggctggaa
     1081 aaaatatgca accgagtcag ttaagctatt cttcaacagc tagtgacaat aacacgcaat
     1141 ctgtagcaaa aggatcaact agcaagccag caaataaatc tgaaaatctc cagagtcttt
     1201 tgaaggaact ctatgattca cctagcgccc aacgttacag tgaatcagat ggcctggtct
     1261 ttgaccctgc taagattatc agtcgtacac caaatggagt tgcgattccg catggcgacc
     1321 attaccactt tattccttac agcaagcttt ctgccttaga agaaaagatt gccagaatgg
     1381 tgcctatcag tggaactggt tctacagttt ctacaaatgc aaaacctaat gaagtagtgt
     1441 ctagtctagg cagtctttca agcaatcctt cttctttaac gacaagtaag gagctctctt
     1501 cagcatctga tggttatatt tttaatccaa aagatatcgt tgaagaaacg gctacagctt
     1561 atattgtaag acatggtgat catttccatt acattccaaa atcaaatcaa attgggcaac
     1621 cgactcttcc aaacaatagt ctagcaacac cttctccatc tcttccaatc aatccaggaa
     1681 cttcacatga gaaacatgaa gaagatggat acggatttga tgctaatcgt attatcgctg
     1741 aagatgaatc aggttttgtc atgagtcacg gagaccacaa tcattatttc ttcaagaagg
     1801 acttgacaga agagcaaatt aaggctgcgc aaaaacattt aaaggaagtt aaaactagtc
     1861 ataatggatt agattctttg tcatctcatg aacaggatta tccaagtaat gccaaagaaa
     1921 tgaaagattt agataaaaaa atcgaagaaa aaattgctgg cattatgaaa caatatggtg
     1981 tcaaacgtga aagtattgtc gtgaataaag aaaaaaatgc gattatttat ccgcatggag
     2041 atcaccatca tgcagatccg attgatgaac ataaaccggt tggaattggt cattctcaca
     2101 gtaactatga actgtttaaa cccgaagaag gagttgctaa aaaagaaggg aataaagttt
     2161 atactggaga agaattaacg aatgttgtta atttgttaaa aaatagtacg tttaataatc
     2221 aaaactttac tctagccaat ggtcaaaaac gcgtttcttt tagttttccg cctgaattgg
     2281 agaaaaaatt aggtatcaat atgctagtaa aattaataac accagatgga aaagtattgg
     2341 agaaagtatc tggtaaagta tttggagaag gagtagggaa tattgcaaac tttgaattag
     2401 atcaacctta tttaccagga caaacattta agtatactat cgcttcaaaa gattatccag
     2461 aagtaagtta tgatggtaca tttacagttc caacctcttt agcttacaaa atggccagtc
     2521 aaacgatttt ctatcctttc catgcagggg atacttattt aagagtgaac cctcaatttg
     2581 cagtgcctaa aggaactgat gctttagtca gagtgtttga tgaatttcat ggaaatgctt
     2641 atttagaaaa taactataaa gttggtgaaa tcaaattacc gattccgaaa ttaaaccaag
     2701 gaacaaccag aacggccgga aataaaattc ctgtaacctt catggcaaat gcttatttgg
     2761 acaatcaatc gacttatatt gtggaagtac ctatcttgga aaaagaaaat caaactgata
     2821 aaccaagtat tctaccacaa tttaaaagga ataaagcaca agaaaactca aaacttgatg
     2881 aaaaggtaga agaaccaaag actagtgaga aggtagaaaa agaaaaactt tctgaaactg
     2941 ggaatagtac tagtaattca acgttagaag aagttcctac agtggatcct gtacaagaaa
     3001 aagtagcaaa atttgctgaa agttatggga tgaagctaga aaatgtcttg tttaatatgg
     3061 acggaacaat tgaattatat ttaccatcgg gagaagtcat taaaaagaat atggcagatt
     3121 ttacaggaga agcacctcaa ggaaatggtg aaaataaacc atctgaaaat ggaaaagtat
     3181 ctactggaac agttgagaac caaccaacag aaaataaacc agcagattct ttaccagagg
     3241 caccaaacga aaaacctgta aaaccagaaa actcaacgga taatggaatg ttgaatccag
     3301 aagggaatgt ggggagtgac cctatgttag atccagcatt agaggaagct ccagcagtag
     3361 atcctgtaca agaaaaatta gaaaaattta cagctagtta cggattaggc ttagatagtg
     3421 ttatattcaa tatggatgga acgattgaat taagattgcc aagtggagaa gtgataaaaa
     3481 agaatttatc tgatctcata gcgtaaggaa tagcagtaga aaaagtctga atcaaaaatg
     3541 aagttctctc aaaagttaga aataaaactc tgactttggg agaatttcat tttattatta
     3601 atatataaaa tttcttgaca tacaacttaa aaagaggtgg aatatttact agttaattaa
     3661 ttggttaatt aatttctata atcatttaat aatgaagaca tcatataaat aattatagaa
     3721 atgaggtaat tatgaaattt aaaaagaaat atatagcagc tggatctgtt gttatccttt
     3781 ccttaagtct gtgtgtttat gctctgaacc aacatagcta acaggccaat acagataaaa
     3841 atcgtgtttc atatgtaaac agtaataaag acactaagaa gactgaaaat ttgactccag
     3901 actaggttag tcaaaaagaa ggaattcaag caaaacaaat tgttattaag attacagatc
     3961 aaggttatgt aacttctcat ggcgatcatt atcactacta taatggtaaa gttccttttg
     4021 atgcgctctt tagtgaagag ccattaatga aagcccccaa ctatcagccg aaagatcaag
     4081 atattgtcag ttaggttaag ggaggatata ttattaaggt agatggaaag tattatgttt
     4141 accttaaaga tcaagctcat gcagaaaatg tacgaacaaa agatgaaatc aatcgccaaa
     4201 aacaagaaca tggtaaagac gataaaggag ctagtgcaga agtatctgta gcaaaattac
     4261 agggacgtta tactaccgat gatggttata tatagtgagt tgaatttaga atagcacatc
     4321 atagtttcta aatcattgtt agaaattact ttaaaatccc cttatcaatt tgctcatatt
     4381 ctatttcaat ctactaatag taccacatgg tggtcactat catttcattc ctgagagtga
     4441 cttgtcggca ggtgaattag cagccacata tgtctttaac cctaatgata ttgtcagaga
     4501 tataggtgat gcttatatag taagacatgg ggaacactat cactatattc ctaagtcatc
     4561 tcttaacaat cccccatcac actctaacac ggaagaggta ggaagttctt ctagttctgt
     4621 attaagtaat ccgtcactac atgtccacca tgaggaagaa gatggtcatg gtttttgatg
     4681 ccaatcgaat tataagtgaa gattcagaag gttttgtgat tcctcatggc gaccacaatc
     4741 actacatcaa ggttcaaact aagggatatg aagcggcttt gaaaaacaag attccatccc
     4801 tgcaatccaa ctatcaacct ggaacttttg atgagaaggc agtcttggca aaagtagatc
     4861 aacttctagc tgatagcaga agcatctaca aagacagatt gagttagctt taggtcagtt
     4921 tactgaaagt ttgaaaaaaa taaaagttag ttgattgatt acttctctaa attttgggca
     4981 cactaaaaag aggtcttgac acctaaactt taaaattaaa gcatattgaa tccgtgctgc
     5041 tgtgcgaagc gaatagcgtc ttggacgaac attgtcttat ctggatttct tatttctgta
     5101 aggccttgta atcttggatt ataactctcc tgttttagga gtacatggta gatagcaacc
     5161 aataatctgc gacagatagc aaggaagaag tagaaagtct tttgaacaag gcaaatcaac
     5221 tcttggaaca aatccatgaa gaaggaatca gacaatcctt ggcagaagaa gtagaaaatc
     5281 taaaagctgc cacaaacaag gctgatgcag acttggatga agtaaacagt caggtaaaag
     5341 atgttttgac tcgtatcgct agcgcccttc aacaagaaaa ggaaaatgct gagcaagatt
     5401 ctcagacact tgtactctat caaaaactct acgatattct catgtcgctt cactcttatt
     5461 tagaaagtaa taatggatct gatgcggact ttgataaggt ggatgcatta ttagatcaac
     5521 tttctgctaa tagtaaagac aaaacagctt tacttgaatc gacaaaagct attctagttt
     5581 tgaatcatca aatccagtca aaagttagcg caagtgaaga aacaagtcca gcaagaaatg
     5641 ctgaagcaaa tagtgataac accagtgctg agaaccaacc aaacgcaact gcagaatcta
     5701 acattgaaac tgctagcgac gaaaacaaac caagcaatac aagagattct aaacctgctg
     5761 aatcaacttc agaaaatgaa acaacagaat cttctacaac tactggaaat caagaaaaac
     5821 cagtagaata aaaagaaagg cgaagtagct gagccacctc gtctttttag cctttataag
     5881 ctacgatgcc aatgatggta tcaactgcac gttccatagt ctgaaggcta acgtattcaa
     5941 aacgtccgtg catattttcg ccacctgcaa agatattcgg agttgggatt cccataaagg
     6001 aaatcttaga gccgtctgtt ccaccccgga ttggttcgat aataggcgtg atacctagat
     6061 cttccataac ggctttagca atggtaattg gagtcatatc tttttcaatg acttctttca
     6121 tattgtagta ctggtctgtc aagttgagag tgacacggtc gctcccaagt tcttcattca
     6181 tcttatcagc gatagattgc atggatgctt tacgcgcttc aaaggcatct ttttcaaaat
     6241 cacgaatgat gtagcttgca cgcacctcct caacactacc tgtcacatcc attagatggt
     6301 aaaaaccttg gtaaccttca gttaactcag gtcggtcatt ttctggaagt tgattatgaa
     6361 aatcaattgc tagctgaagg gcattgacca tctgcccttt ggcagtacca gggtggacat
     6421 tacggccttg gaaatgcaat tcagcaccag cggctgagaa agtctcgtac tgaagttcac
     6481 ctagtggacc accatcaaca gtgtaggcaa aatccacatc aaaatcttct gcatcaaatt
     6541 tattggcacc aacaccgatt tcttcatctg gaccaaaacc aacacgaatc tcacagtgct
     6601 taatttcagg atgagcagtt agatattcaa tggctgtcat aatttcagca attcctgact
     6661 tgtcatcagc acctagcaag gttgttccat ctgttgtgat gagtgtttgt cctggatatt
     6721 tttcaagact cttgaagtcg gctggatcga gtttgaaacc agaattccct agttcaatca
     6781 caccaccatc gtagttttca attacctgtg gattgactcc ttcagcatta aaatcagcag
     6841 tatccatgtg cgatataaaa ccaatcttac gtgttaaaga cggatcgttg gctggcaagg
     6901 ttccaatagc aaaaccattc ggtagatagt aaacattttg cagtccaaca cgtttcattt
     6961 caggaattag gacatttgtt gcgaagtcaa cctgactctg tgtacttgga gtagtagtag
     7021 agtgttcatc agagcgcgtg ttgaccttaa cgtaggttaa gaagcggtcc aagagatttg
     7081 gataagtcat aaaaaaactc cttttttatc ataaaataga atacaaaact tcggaaaaat
     7141 atgatttgag aaattt
//
LOCUS       DAVKMJ010000073         6923 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000073 DAVKMJ010000000
VERSION     DAVKMJ010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6923
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.073"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(112..387)
                     /locus_tag="VW348_002004"
     CDS             complement(112..387)
                     /locus_tag="VW348_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEU9746851.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(494..1333)
                     /locus_tag="VW348_002005"
     CDS             complement(494..1333)
                     /locus_tag="VW348_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEU9746852.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1475..2323
                     /locus_tag="VW348_002006"
     CDS             1475..2323
                     /locus_tag="VW348_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEU9746853.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSAWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2416..3333)
                     /locus_tag="VW348_002007"
     CDS             complement(2416..3333)
                     /locus_tag="VW348_002007"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEU9746854.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3679..3887
                     /locus_tag="VW348_002008"
                     /pseudo
     CDS             3679..3887
                     /locus_tag="VW348_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4197..4490)
                     /gene="rpmA"
                     /locus_tag="VW348_002009"
     CDS             complement(4197..4490)
                     /gene="rpmA"
                     /locus_tag="VW348_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEU9746855.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4507..4851)
                     /locus_tag="VW348_002010"
     CDS             complement(4507..4851)
                     /locus_tag="VW348_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEU9746856.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4867..5181)
                     /gene="rplU"
                     /locus_tag="VW348_002011"
     CDS             complement(4867..5181)
                     /gene="rplU"
                     /locus_tag="VW348_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEU9746857.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5217..5304)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5369..6067)
                     /locus_tag="VW348_002012"
     CDS             complement(5369..6067)
                     /locus_tag="VW348_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEU9746858.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKA"
     gene            6469..6768
                     /locus_tag="VW348_002013"
     CDS             6469..6768
                     /locus_tag="VW348_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEU9746859.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         2177 a         1394 c         1154 g         2198 t
ORIGIN      
        1 aatattttcg gaacattcaa ctttttaact ctatttatta ctagatttca taattaaaaa
       61 gcctactgac caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac
      121 agcgtcttta agagctttac cagctttgaa tgctggtact ttagaagctg caattgtcat
      181 ttctttacca gtttgtgggt tgcgaccttt acgttctgcg cgctcacgaa cttcaaagtt
      241 accaaaaccg atcaactgaa ctttttcacc agctgcaaga tagtcagcta ctgctgcaaa
      301 tacagcttca actgctgctg ctgagtcttt cttagttaat tctgtagctt ctgctacttt
      361 agcgatcaaa tcttgtttgt ttgccatgtt aatgattcct ccaaataatt tctaattaac
      421 aaatataatc atatcctaaa atccctttta ggtcaagtta aaaacgctat ttcttcccat
      481 tttatttatt tttttaggag tggtaacgta tcaaaatagc ccaagcgttc tcacccgtgt
      541 gagtttgaat aatggaaccc gtttccaaaa cagaaattgg cttttcaaca taagcttgta
      601 agctttcttt catctctttt gcccaatcat cactaccaga atatgaaatt ccaatctctg
      661 ctacagcacg ttcagaaagc gatgttatca actcatctaa ccatttttta aatgttttag
      721 ttccacgacc tttaaccatt ggctgcaatt catggtcttt catttgcatg acaacacgga
      781 tattgagaag agagctcaac aagccagtta cacggctaat tcgtccacct ttgacaagat
      841 tttccaaagt tgaaacacca atataaagct ctgtatggtt tttaacctct tctacatgag
      901 ataaaattgc ctccatatct ttaccttctt gagctaactt cgcagcctca acaacttgga
      961 atttcagggc ttggtcagtg aaggaactat caacaacagt cacatctgca gtagataggc
     1021 tagcaccttg gcgtgctgct tctaccgtac ccgaaagagc atgggacata tgaatagcaa
     1081 gaatctggcc accatctttg cataggtctt caaaaatctc agcaaagaca cctacaggtg
     1141 gctgacttgt tttcggaaga ttcttacttt cttgcatcaa ctgaagaaat ttaccttctt
     1201 ctttcaaatc cgcatcagaa taaacaacat tatcaatcat tacagataat ggaacaattg
     1261 taatatctaa ttgctttact agttcaggtt caatagtaac agatgaatcg gttacaatct
     1321 taatttttgt catagtatca atctttctat tttaggattc agattggttt ccttacttct
     1381 aattatatca aaaaaaagat taaaaatcct aatggagtca atcaaatttt ccgtaaaatt
     1441 tgatataatc aacttataag aaaagaggtg tcctatgatt aaaaaaattt accccatttt
     1501 taccatttta ctaggtgctg ctatttatgc ttttggactg acttattttg tagttcccca
     1561 tcatctcttt gaaggagggg cgacaggcat taccctcatc accttttatc tttttaaaat
     1621 ccctgtttcc ctcatgaacc tgctgattaa tattcccctt ttcatcctag cttggaagat
     1681 ctttggagcc aaatccctct attctagttt actaggaacc ttagctttgt ccgcctggtt
     1741 agcttttttt gagcatattc cccttcatat tgatcttcaa ggtgatttac taatcacagc
     1801 ccttatagcg ggaatcctat tgggaattgg ccttggaatt atttttaatg ctggaggtac
     1861 aactggcgga actgatattc tagctcgtat tctcaacaaa tacactcata tatccatagg
     1921 aaaactgctc tttatcttag atttttgtat tctcatgttg attctcctaa tcttcaagga
     1981 tttgagattg gtttcctaca cgcttttgtt tgattttatt gtttctcgtg ttattgattt
     2041 gattggtgaa ggaggatatg ccggcaaagg ctttatgatt atcacaaaac gtcctgacca
     2101 acttgctaag gcgattaatg atgacctcgg aagaggtgtt acttttattt ctggtcaagg
     2161 ctactatagt aaagaaaatt tgaaaatcat ctactgtatt gtcggaagaa atgaaattgt
     2221 gaaaacgaag gaaatgattc atcgaatcga tcctcaagcc tttataacta ttacagaagc
     2281 ccatgaaatc ctaggagaag gcttcacctt tgaaaaagaa taaaaagagg taatgtcgtg
     2341 acctcaaaag ttagactaaa tcatctatct tttgggttac agacaacctc ttttttgttt
     2401 tatttactca agctcttaag accaattccg agttacttct tcatcagcct ttaactgatc
     2461 cactaattgg tcaactgagt caaatttggt catatcacga atgcgatcaa gccaataaac
     2521 catgacggtt tccccataaa tatcttgatt aaaatcaaaa atattgactt caaaacgtgc
     2581 ttcttctcca tcaaaggtca catttttccc gacactagcc atagcacgat acttctgtct
     2641 ttgaatctca acatcaacga cataaacgcc atctgctggc atataagtac ggtctaaaag
     2701 cactaaattc gctgtcggat aaccaattgt acgaccacga gcattaccat gaactaccat
     2761 acctcttgat ggaagcggtg cccccaaaag ttttcctgct tctttcacat ttccatctaa
     2821 aatagcttga cggatacgag ttgaactaat ctttcctttc tcatcttcta caggtggaac
     2881 aatgataact tctccatcaa agtaatcctt taaatcttct gctgtttttt tgtcagaacc
     2941 aaatgtataa tcaaaacctg caacaataat tttggcattc atagccttga tataagttgc
     3001 aaagaattct tgtgcagtaa gactagcgaa ttgactacta aaatcaagga gatataattc
     3061 ttctacacct tcgcgcttta attttctttc acgttcagca gggttcaaaa tatgcaaaaa
     3121 caaatctgga tgataaggct ctaaagcgat ctttggagat tcattaaagg tcataacgac
     3181 gataggtaat aaatcctttc tcgcagcctt gttggcaaca cgaaataatt cttgatgccc
     3241 cttatgtatg ccatcaaaat agccgagaac aacgactgaa tcagatggtg tgccaatatc
     3301 tttttggttt tttataggaa tagtaataat cataaaataa ttatatcata gcgatagcta
     3361 tttctggaac agaaaatctg aaatgttgtt tttttcacat gaagtgtacc tgttttcaaa
     3421 aagcacttta ttctatcgtt gcttaactat gaactttgca atattcttct caaaaacttg
     3481 taggacatct tcaaaatttt gcaaggagtg attagacttg ttcggtaacc ataaagtgtc
     3541 atactatgtt atgtatgaaa aagcaatgca actaactcct gagaacttta aattactaat
     3601 tggtgccgaa aaggtagaat ttagaatcga ggtacaccta tggctgtaaa atttacaaaa
     3661 tgagacaact tgggcaagat gtttgaagaa tttcctaaac tcccatctag tgtgcttcag
     3721 actaggctat ttttctctcc atctgttagc ttggattctc agaccgtttc agctaaagaa
     3781 tatcttttcc cttatcagaa ggaacggctc aagccattca gacaagtgaa gggacgacaa
     3841 gccaatattt gaaaccagat agcagttctt atagtcaatt gaaataaaat ctgaagaaat
     3901 cgagtaggaa actcatatca atttttaaca gtgttctatt ccagattcat actcaatgaa
     3961 aattaaagtg caaactagga agttagccgc aggctgtact tgagtacggc aaggtgaaat
     4021 tgacgtggtt tgaatttgat tttcgaagag tatcaatcca ctatacatat taaaaagtat
     4081 gggtatcaaa ataaaaaaca ggctctccga aaactcggaa agccttattt taagctgttt
     4141 ctagcttcct cacctttaca tttcaaggtt cgggataaaa ggttcaatgg acctttttat
     4201 ttagcgattg ggtaaacaga aacttgtttt ttatcgcgtc ctttacgttc aaagcgtact
     4261 acgccttcaa ctttagcgaa caaagtatcg tctccaccac gaccaacgtt tacacctgga
     4321 tagatgtgtg taccacgttg acggtaaagg attgatccac ctgttacagt ttgtccgtca
     4381 gctgctttag ctccaagacg ttttgcttgt gaatcacgtc cgtttgatgt agaacctcca
     4441 ccttttttgt gggcgaaaag ttgcaagttg ttaagagtca tttttaacat aatgttttcc
     4501 tccgtgttag ttttctgtga taactctggt ttggacgaac tcagaatagt tctccgataa
     4561 gtttgccata cctaagaaaa atgattcaaa gaataactgg gtcatttctc tctggtgtga
     4621 aggaagatct tttggtattt caaccatcag atagccacct tcatcttcgt ttaattctag
     4681 gattggttca tagcctgcaa atttctcaat agaattgata aagttaatgg caagcgtaga
     4741 aaccgatgca cacacgacat ctaagccgta ttcgccactc tcggcgtgtc cagtaatttc
     4801 cgcactcctc agctcgccat cttcggctct ctcaaagact gcctgtatca tgtgttctcc
     4861 ttaaaattaa gcgttgattg cgttgatgac aacttttgta tatggttgac ggtgaccttg
     4921 tttacggtgg ctaccttttt taggtttgta cttgtaagta accactttct tttgttttcc
     4981 ttgtttttca acagttccaa ctacagtagc tccagcaaca agtggagttc cgacaacagt
     5041 gttttcacca ccaacaagaa caacttcgtt aaaagtaact tcttgaccag cttcaacgtt
     5101 caatttttca acgtaaactg cttgaccaac ttcaacttta acttgttttc cgccagtttt
     5161 gataattgcg tatgtgctca ttatgcacct cctatgattt ttatgggttt ccccgatttt
     5221 ttgtgaagac tcgcctagca tcgtgggacg aaccacttaa acttgaataa tcaagcaacg
     5281 atgttcgtgc ggttgcacag gatcgtgcat agtcaactct tcaagtatag catatctcct
     5341 attttcttac aagtaataac acctaaaatc aagctttttc ttttactttt ttctgccaag
     5401 aggcaaaaag catgctgagg taaaaaacgc tcatcataat aggaacacca agaatggtct
     5461 tttcatgata gaaaatcgtc aaataggctg aaaagacaac gccaaggaca aaactactaa
     5521 gcaggctaac aaatatgaat ccttcacgca aaaaaggagt gtgcttggtt cggaaataat
     5581 ctccaaaagc cagcatggtc cgtttgatat tccctgtcat aaaagcgtta ttataggcaa
     5641 tacccgacac ttctccaaaa gcagttgtca ccagtcccat acagaaggcc aagggcggca
     5701 ctagatagat attatccaca gtttgcggca caaaagcaat aatgattgat aagattgcca
     5761 agggaatcaa ggacagaata ggttttttca caattctcaa tttttcctta taaatcgtta
     5821 ataaaaagac tcccatcata aacgctagca aggtgagaac cttgtcccta acatccgaaa
     5881 cattattttt aattaattct actgaaagaa agacaacatt tccagtttgt ccagctacaa
     5941 gggtattccc gcgaacaata aaagtgtaag catccacata tccagcacaa aacgtcaaaa
     6001 aaagtgctaa ccttttagac tgacgtgata tttttcttat aggtaataac ctcattttac
     6061 ctcccattgt attttctctt agaaatattg taccattttc tttctaaaaa atcgtaggct
     6121 accatttaga ttttactatt agcataaaaa taataataga caactattta tccaaaaata
     6181 gatagatgta acatgtttgc aaacaaagca tacgaacctt tagtaaaatc atttccatga
     6241 aactagaata gagccctctt agcaaaaatc attattttaa tttatttcta atcactcctt
     6301 gacataaata actctcacca ataaaagact atgtcttaaa aaaatggtat aataaaatca
     6361 atacttgggc ttgatggcta tgctactaat aacaattagg agagaaaatc aggcacttgt
     6421 taacaacaag gattatcccc ttgagatgaa aggaacttta gaaatcttat gatgaacatg
     6481 caaaacatga tgcgtcaagc acaaaaactt caaaaacaaa tggaacaaag ccaagctgaa
     6541 cttgctgcta tgcaatttgt tggcaaatct gctcaagatc ttgtccaagc gaccttaact
     6601 ggcgataaga aagttgtcag cattgatttc aatccagctg tcgttgaccc agaggacctt
     6661 gagactcttt ctgatatgac cgttcaagcc atcaactctg ctcttgaaca aatcgatgaa
     6721 actaccaaga aaaaactggg tgctttcgct gggaaattac ctttctaaaa acaaggagct
     6781 agaacaatgc ttgtcgataa caaaggctaa gaaaggtgca aaaatgactc tataatattt
     6841 gtagtgggta aatccactat agatattatg gagcctattt tattgtagaa aaaaagtccc
     6901 ataagatcta taatgaaaag cga
//
LOCUS       DAVKMJ010000074         6889 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000074 DAVKMJ010000000
VERSION     DAVKMJ010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6889
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.074"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..497
                     /locus_tag="VW348_002014"
                     /pseudo
     CDS             1..497
                     /locus_tag="VW348_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            664..864
                     /locus_tag="VW348_002015"
     CDS             664..864
                     /locus_tag="VW348_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746860.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            889..1305
                     /locus_tag="VW348_002016"
     CDS             889..1305
                     /locus_tag="VW348_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746861.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLDVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1536..2243
                     /gene="ccdA2"
                     /locus_tag="VW348_002017"
     CDS             1536..2243
                     /gene="ccdA2"
                     /locus_tag="VW348_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEU9746862.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            2254..2811
                     /gene="sdbB"
                     /locus_tag="VW348_002018"
     CDS             2254..2811
                     /gene="sdbB"
                     /locus_tag="VW348_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEU9746863.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2932..4323
                     /locus_tag="VW348_002019"
     CDS             2932..4323
                     /locus_tag="VW348_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEU9746864.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4466..5383
                     /gene="adcAII"
                     /locus_tag="VW348_002020"
     CDS             4466..5383
                     /gene="adcAII"
                     /locus_tag="VW348_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEU9746865.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            5391..>6889
                     /locus_tag="VW348_002021"
     CDS             5391..>6889
                     /locus_tag="VW348_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEU9746866.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQITYRTVNGVAVPHGDHYHFIPYSQLSPLEEKLA
                     RMIAVKGQNGAVLPGMHYLKPAPKPQVQPSTEKKQTDFAVEQVVRKVGEGYVVEIAGV
                     SHYVFAKDLAKDKIDAIENLLSKKTQETHALVAKKENVAPRDQEFYDKAYNLLTQAHK
                     VLSENKGRTSDFQALDKLAERLNNESSNKVKLVDDLLAFLAPITHPERLG"
BASE COUNT         2142 a         1252 c         1438 g         2057 t
ORIGIN      
        1 ccaagtaaaa ggaacaaaac caagaaaagt tgatagagat agacttaaaa actatcttac
       61 tgacaatcca gacgcttatt tgactgaaat agcttctgaa tttggctgtc atccaactac
      121 catccactat gcgctcaaag ctatgggcta cactcgaaaa aagaaccaca cctactatga
      181 acaagaccca gaaaaagtag ccttatttct taagaatttt aatagtttaa agcacctagc
      241 acctgtttag attgacgaaa caggattcga tacttatttt tatcgagaat atggtcgctc
      301 attaaaaggt cagttaagaa gaggcaaagt atctggaaga agatatcaga gaatttcttt
      361 ggttgcaggt ctaacaaatg aatggtgagt taatcgctcc aatgacttac gaagagacga
      421 tgacgagcga cttttttgaa gtatggtttc agaaatttct cttaccaaca ttaaccacac
      481 catcggttat tatagtaaaa tggaataaga acaggacaaa tcgatcagga cagtaaaatc
      541 gaattctaac aatgttttag aagtctatat gtactattct agtttcaata taccataact
      601 gctcctagtc aacctgcaag tcctgtccca gctccaagct cagctccgac tcaagatcct
      661 agagtggtag caagcgcttc ggctagctca acgagcacac aagctcaaga gcaagttgac
      721 aagtctgaac ttcgtgcctt gagtcaagag ttagaccaac gcttgaaagc tttggcaaca
      781 gtatctgatc caaaaatcga tgcaaccaag gctgtcctcc tagatgctca aaaagctccg
      841 gaagatagtg ccttgacaga gtaaggtctg catactgcag tagagtctgt gaaggctgcc
      901 ttggactctc tcaaagatgt gaaagcaaat gctagcgaca gcaagcctgc acaggacaag
      961 aaggatgcaa aacaaggaac ggaagatagt aaggattcag ataagatgac tgaaacaaac
     1021 tcagttccgg caggagtgat tgtggtcagt ctacttgccc tcctagacgt gattgccttc
     1081 tggctgattc gccgtaagaa agagtcagaa atccagcaat taagcacgga attgatcaag
     1141 gttctaggac agctagatgc agaaaaagcg gataaaaaag tccttgccaa agcccaaaac
     1201 cttctccaag aaacccttga tttcgtgaaa gaagaaaatg gctcagcaga gacagaaact
     1261 aaactagtag aggagcttaa agcaatcctt gacaaactca agtaaaacat gatttatgaa
     1321 atgtcagacc taaaagacat tttcgttcac aaaagcagtg acgagtaatc cttgtcgttg
     1381 ctttttggct attttggggg ataagatccg ccttgactag caaaagaaaa gattggtcca
     1441 atagtgcccg atacgatttt gcgtagcaga aagcttacaa ataaaattga atatagtaaa
     1501 ataggattag aattattaag aaagttggtt ctttattgga aacgatagta tttttaatct
     1561 ctgtttttct agcaggtgtt ttatcctttt tttctccttg tatttttcct cttctgccag
     1621 tctatgctgg gattttattg gatgatcaag aaagtgcaaa aagcttttct ttgtttggga
     1681 gaaaggttct ctggtcaggc ttgattcgaa cactttgctt tatcgctggt atctctctca
     1741 ttttctttat tctaggcttt ggtgctggtt actttggtca tattctctat gcaaattggt
     1801 ttcgatatgt catgggagct attattatca ttttgggtct tcaccagatg gaaatttttc
     1861 atttgaagaa attagaagtt caaaaaagtt ttacctttaa aaaatcagat tctaatcgtt
     1921 attggtcagc ttttttactt ggtattacct ttagctttgg ttggacacct tgtattggtc
     1981 cagttttaag ttctgtttta gcacttgcgg cttctggagg caatggtgct tggcaaggag
     2041 cgatttatac tctcatttac actctgggca tggcccttcc tttcttggtc ttggcactag
     2101 cttcaggtct agtcatgcca tattttagta aaatcaagcg tcatatgatg ctactaaaga
     2161 aaattggtgg tttcctcatt gttttaatgg gaattttgtt actattagga caagtaaatg
     2221 ttctagctgg aatttttgaa taaaggagga caaatgaaaa aagtaatgtt tgctggctta
     2281 agtctcttgt cattagttgt attgatggcc tgtggtgagg aagaaactaa aaagactcaa
     2341 gcagcacaac agccaaaaca acaaacgact gtacaacaaa ttgctgttgg aaaagatgct
     2401 ccagacttca cattgcaatc catggatggc aaagaagtta agttatctga ttttaagggt
     2461 aaaaaggttt acttgaagtt ttgggcttca tggtgtggtc catgcaagaa aagtatgcca
     2521 gagttgatgg aactagcggc gaaaccagat cgtgatttcg aaattcttac tgtcattgca
     2581 ccaggaattc aaggtgaaaa aactgttgag caattcccac aatggttcca ggaacaagga
     2641 tataaggata tcccagttct ttatgatacc aaagcaacca ccttccaagc ttatcaaatt
     2701 cgaagcattc ctacagaata tttaattgat agccaaggaa agattggaaa gattcaattt
     2761 ggtgctatca gtaatgcgga tgcagaagca gcatttaaag aaatgaacta gaatcgataa
     2821 aatctgatta caagatgtag tcagattttt ttagaaaaac attttataaa tattcacata
     2881 tctcctatat ttatggtaaa atagaattat cagtttattt tggagtcaaa gatgaatata
     2941 tttagaacaa agaatgttag tttagataaa acagagatgc ataggcattt gaagttatgg
     3001 gatttgattt tgctgggtat cggagccatg gtagggacag gcgtctttac aatcacaggt
     3061 actgcagctg caacacttgc tggcccagcc ctagtgattt caatcgttat ttctgccttg
     3121 tgtgtgggat tatcagccct cttttttgca gaatttgcct cgcgagtacc cgctacagga
     3181 ggtgcctata gttacctcta tgctatctta ggagaattcc ctgcctggtt ggctggttgg
     3241 ttaaccatga tggagttcat gacagccata tcaggcgtag cttcgggttg ggcagcttat
     3301 tttaaaggct tgctctctca atacgggata gcctttcctc aggctttaaa tggtaccttt
     3361 aatcctcaag cagggacatt tgttgattta ttgcctattc ttgtcttggt cttggtgact
     3421 tcgcttgttt tactaaatgc caaggcagcc ttacgcttta attcgattct agttattttg
     3481 aaattttccg ctttagctct ctttgtttta gtaggaattt ggaatattaa gtttgataat
     3541 tggagcaatt ttgctcctta cggttttgga caaatctatg gagctagcac tggtattatg
     3601 gctggtgcgt ccttgatgtt cttcggtttt ttgggatttg aatccatctc tatggctgta
     3661 gatgaagtca agactcctca aaaaaatatt cctagaggga ttgtcttatc gctttctatc
     3721 gtaaccattc tctatgcctt ggtgaccctt gttttgactg gtgtggttca ctatagtcat
     3781 ttaaatgtcg atgatgccgt tgcctttgcc cttcgtagtg ttgggattag ttgggcagcc
     3841 aactatgtgt cattagtggc tatcttgacc ttgattacag tttgtatttc gatgacctat
     3901 gccctatcgc gtatgattta cagtttagca cgtgacggct tagtgcctgc tgcctttaag
     3961 gaactgacga agactagcaa gataccaaag aatgctacta tcttgacagg tctagcttca
     4021 gcagtagcag caggaatgtt cccactagcc agtattgcag cctttttaaa tatttgtacc
     4081 ttagcctact tgatcatgct ggcttatggt ctgattcgct tacggaaaga aaaaggaatg
     4141 cccaaagctg gggaatttaa aacaccattg gtacctctgt taccaatttt atcgatcatc
     4201 atttgtttat ccttcatgtt acagtataat atgaacacct ggattgcttt cctagttgcg
     4261 ttgttagtag gaagtattat ttacttcact tatggctata agcattctac catagaagaa
     4321 taaagtgaaa gtctattgag ttgttgacac tcagtagatt tttatatgtg aaagaaattt
     4381 caaatttttt ctaaaaatat cttgacagat taaattttca ggagtagaat atttactagt
     4441 taattaaatg gttaaggagt tgttcatgaa gaaacaaaat ttatttttag tcctgttaag
     4501 tgtctttctt ttgtgtttgg gggcttgtgg tcaaaaggaa agtcagacag gaaaggggat
     4561 gaaaattgtg accagttttt atcctatcta cgctatggtt aaggaagtat ctggtgactt
     4621 gaatgatgtt cggatgattc agtcaagtag tgggattcac tcctttgaac cttcggcaaa
     4681 tgatatcgca gccatctatg atgcagatgt ctttgtttac cattctcata cactcgaatc
     4741 ttgggcagga agtctggatc caaatctaaa aaaatccaaa gtgaaggtct tagaggcttc
     4801 tgagggaatg accttggaac gtgtccctgg actagaggat gtggaagcag gggatggagt
     4861 tgatgaaaaa acgctctatg accctcacac atggctagat cctgaaaaag ctggagaaga
     4921 agcccaaatt atcgctgata aactttcaga ggtggatagt gagcataaag agacttatca
     4981 aaaaaatgcg caagccttta tcaaaaaagc tcaggaattg actaagaaat tccaaccaaa
     5041 atttgaaaaa gcgactcaga aaacatttgt aacacaacat acagcctttt cttatctagc
     5101 gaagagattt gggcttaatc aacttggtat tgcaggtatc tctcctgaac aagaaccaag
     5161 tccacgacaa ctaacagaaa ttcaggaatt tgttaagacc tataaggtta aaacgatttt
     5221 tacagaaagt aacgcttctt caaaagtagc tgaaactctt gtcaaatcaa caggtgtggg
     5281 tcttaaaact ctgaatcctt tagagtcaga cccacaaaat gacaagacct atttagaaaa
     5341 tcttgaagaa aatatgagta ttctagcaga agaattaaag tgaggaaaga atgaaaatca
     5401 ataaaaaata tctagcaggt tcagtggcag tccttgccct aagtgtttgt tcctatgaac
     5461 ttggtcgtca ccaagctggt caggttaaga aagagtctaa tcgagtttct tatatagatg
     5521 gtgatcaggc tggtcaaaag gcagaaaatt tgacaccaga tgaagtcagt aagagagagg
     5581 ggatcaacgc cgaacaaatt gttatcaaga ttacggatca aggttatgtg acctctcatg
     5641 gagaccatta tcattactat aatggcaagg ttccttatga tgccatcatc agtgaagaac
     5701 ttctcatgaa agatccgaat tatcagttga aggattcaga cattgtcaat gaaatcaagg
     5761 gtggctatgt gattaaggta gacggaaaat actatgttta ccttaaagat gcagcccatg
     5821 cggacaatat tcggacaaaa gaagagatta aacgtcagaa gcaggaacgc agtcataatc
     5881 acaactcaag agcagataat gctgttgctg cagccagagc ccaaggacgt tatacaacgg
     5941 atgatgggta tatcttcaat gcatctgata tcattgagga cacgggtgat gcttatattg
     6001 tccctcacgg caatcacttc cactatattc ctaagagtga tttgtctgcc agtgaattag
     6061 ctgctgccca agcctattgg aatgggaagc agggatctcg tccttcttca agttctagtc
     6121 ataatgcaaa tccagctcaa ccaagattgt cagagaacca caatctgact gtcactccaa
     6181 cttatcatca aaatcaaggg gaaaacattt caagcctttt acgtgaattg tatgctaaac
     6241 ccttatcaga acgccatgta gaatctgatg gcctagtatt tgatccggca caaataacat
     6301 atcgtacagt caatggtgtt gctgtaccgc acggagacca ttatcacttt attccttatt
     6361 cacaactgtc acctttggaa gaaaaattgg ctcgtatgat tgctgttaag ggacaaaatg
     6421 gtgcagtctt gccaggaatg cattatttga aaccagcacc aaaaccgcaa gttcaaccat
     6481 caactgagaa aaaacaaact gattttgcag tagaacaggt tgttagaaaa gttggagaag
     6541 gctatgttgt ggaaattgct ggtgtcagtc actatgtttt tgctaaagac ttggctaagg
     6601 ataagattga tgctattgaa aatctcttgt ctaagaaaac tcaagagaca catgctctag
     6661 ttgctaaaaa agaaaatgtc gctcctcgtg accaagaatt ttatgataaa gcttacaatc
     6721 tgttaaccca ggctcataaa gtcttgtctg aaaataaagg tcgtacttct gatttccaag
     6781 ccttagacaa attagcagaa cgcttgaata atgaatcttc taataaagta aaattggtag
     6841 atgatttatt ggcattccta gcaccaatta cccacccaga acgccttgg
//
LOCUS       DAVKMJ010000075         6693 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000075 DAVKMJ010000000
VERSION     DAVKMJ010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6693
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.075"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            11..563
                     /locus_tag="VW348_002022"
                     /pseudo
     CDS             11..563
                     /locus_tag="VW348_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822207.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            491..943
                     /locus_tag="VW348_002023"
     CDS             491..943
                     /locus_tag="VW348_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746867.1"
                     /translation="MEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYSDYS
                     KDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQVVIM
                     ESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            1762..2121
                     /locus_tag="VW348_002024"
     CDS             1762..2121
                     /locus_tag="VW348_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746868.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIAE
                     VNQVQSLSRGFREKYMR"
     gene            2131..2496
                     /locus_tag="VW348_002025"
     CDS             2131..2496
                     /locus_tag="VW348_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEU9746869.1"
                     /translation="MVYRYRTNLKKVFLTDSELHQLNERIAKSNCQNFSVYARKVLLN
                     PNMSFVTINTDTYDQLVFELRRIGNNINQIARAINQSRLISQEQLQELSKGVGELIKE
                     VDKEFQVEVKRLKEFHGSH"
     gene            2483..4333
                     /locus_tag="VW348_002026"
     CDS             2483..4333
                     /locus_tag="VW348_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEU9746870.1"
                     /translation="MVVTKHFATHGKKYRRRLIKYILNPDKTDNLKLVSDFGMSNYLD
                     FPSYEEMVEMYNVNFTNNDKLYEYRNDRQEKHQQNIHAHHLIQSFSPEDNLTPEEINR
                     IGYETIMELTGGRFRFIVATHTDKDHIHNHILINAIDCNSDKKLIWNYALERNLRMIS
                     DRISKMAGAKIIEKRFSYRDYQKYRATSHKFELKQRLYFLMQQSKSFDDFLEKAEQLH
                     VHIDFSQKHSRFMMTDRAMTKPIRGRQLSKRDLYDEDFFRMHFTKQEIASRLEFLLNC
                     VNSLEGLLTKSKELNLTIDLKQKNVIFILEENGKQFSLSHKKISDEKLYDVNFFQDYF
                     KNKEVGVSEGIENLQAQYRAFQEERDKEKVSTEEIEEAFETFKEKRDAVHEFEVKLTE
                     HQIEKLVDEGIYIKVSFGINQSGLIFIPNYQLDIMEEENQKKYKVYIRETTSYFVYNK
                     EHSDKNQYIKGRTLIRQLTNDSRVIPYRRPTVERLQEKISEISLLIELTETDKKYQDI
                     KDNLVSEIAELDIKLTQTNEKIATLNKMAEVLINSKSEGSGSQKLARHEFSKLNMTES
                     TTLEQVNEELLKLQQEFGNVLDEYEKTIRKLGQLFKVFDECINKEIMNEI"
     gene            4589..6021
                     /locus_tag="VW348_002027"
                     /pseudo
     CDS             4589..6021
                     /locus_tag="VW348_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886556.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(6259..6393)
                     /locus_tag="VW348_002028"
                     /pseudo
     CDS             complement(6259..6393)
                     /locus_tag="VW348_002028"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT         2330 a         1056 c         1308 g         1999 t
ORIGIN      
        1 ataagacaat ttttttagta attttgataa ggttgttttt tctagttcaa aagaatatat
       61 tagttttctt atgttagcag aggcaatcat aaaaaatgga atagaaatag ttgtagtaac
      121 tgatcataat actaccaaag gtattaaaaa gttacaaatg gcagtctcaa tcataatgaa
      181 aaattatccg atttatgata tacatcctca tattttacat ggagtagaaa ttagtgcagc
      241 agataaattg catattgtat gtatatatga ttatgaacaa gaatcatggg ttaatcaatg
      301 gttaagtgaa aatattataa gtgagaaaga tggaagttat caacattcac tgactataat
      361 gaaggatttc aataatcaaa aaatagttaa ctatattgct catttcaata gttatgacat
      421 tttgaaaaaa ggttctcact tatcaggtgc atataaacga aaaatttttt ctaaagaaaa
      481 tacacgattt ttggagttta atattaactc gaaagaatct tcgcaacaac ttgatattct
      541 ctataaagaa gttggtgtat taagtttggg acaaaaagtt gtagccatgc ttgatttttt
      601 attagcatat agtgactatt ctaaagactt cagaccattg attattgatc agcctgaaga
      661 caatctagac aatcgttata tttacaggca tttagttcag cagtttagag atgtgaaagc
      721 tcaacgtcaa attattttag caacacataa tgctacaatt gtaacaaatt ctatgacaga
      781 tcaagttgtt attatggagt cagatggagt taacggatgg attgaatcac agggatatgt
      841 tagtgaaaaa tatataaaaa atcatatcat caatcaatta gagggaggaa aagattcctt
      901 caagcataaa atgtctatat atgagacggc tttatcagag tagagtcaga aaaagtaggt
      961 tagaaattta gcctactttt ttctttgttc gacaggcata gtgtacatct gaggtccaag
     1021 tcctctgtgg atatttgctg cagatgaaac caatagcgac tcctaagcct gaatatcgtg
     1081 aggtaggggg gataggaagg aattagcgaa atcaaggttc tacaaacaga atcgtgactt
     1141 gaagccatat atagcggatg aggaactcta aaatccaaat aggtgtcgta acctatatac
     1201 gtaaattacg agagtaaact aggaaagatg tacggcttat tccgtgagcg tttaggacgt
     1261 agtacaacga atcatgggag tcagctgaac acatagtatt gaagaaattt ctgtaatgga
     1321 aatggagcga agaagtgaac aattaaatga atacctctct aattaaattt gtcaattcta
     1381 attcctggta tgaaaagaca gtgacctaaa aatgtaaacg atgggagctg atcataaata
     1441 taggacggta catgcagtgg tgttagagat tagtccctac ttgatttgtg ataacttccc
     1501 caactttctt ctgctatact tttctcaact tttaaaaatc caactaagaa ttttacctgg
     1561 gagtttgggg gcgtagccac caagttatct tatggttagc tgtcaaaact ggaaggtttt
     1621 ggttagctgg cgatatgatt ttttgggtat tgtgaccaca atgcctgagc tcgcaaagac
     1681 cgaacaagga ctttaagaaa tttcccgtat gacacacggg gtcggggttt acccgagaaa
     1741 ggatgaaagt gaggaaaaga gatgtctgaa cagtaccgtg acattcgaaa agaggtaaat
     1801 ctaaccgcag atgagctaaa acagattgaa aaaatgatgg aggttgataa ttatcgtcac
     1861 ttttcaccat tcgtcaggga taaaattttg atgactgatg acaaacagtt agctgccaaa
     1921 gaatggtttt ccctttggca gtctcaaaag tttgaacaga tcagtcgaga tgtgcatttg
     1981 gttttgatta tcgcaagaga gaatcaccaa gtgactcaag aacacgtgtc aatcttattg
     2041 acctgcgttc aagaattgat tgcggaagtc aatcaagtac agtcactcag tcgtgggttt
     2101 cgtgaaaaat acatgagata ggaggctact atggtttatc gttatcgtac caatctcaaa
     2161 aaagtatttc taacagattc agaattacac caattgaatg aacggattgc taagagcaat
     2221 tgtcaaaatt tttcagtcta tgccagaaaa gttttgctta atcccaatat gtcatttgtc
     2281 acgattaaca cggatactta tgaccagtta gtttttgaat tgagacggat cggaaataac
     2341 attaatcaaa ttgcgcgtgc tatcaatcaa agccgtctga tttctcagga acagttacaa
     2401 gaattgagta aaggagtcgg agagttgatc aaggaagtgg acaaagaatt tcaagtggaa
     2461 gtgaaaagat tgaaggagtt tcatggtagt cactaagcat tttgcgacac acggaaaaaa
     2521 atatcgtagg cgtttaatta agtatatcct caatcctgat aaaacggaca atttgaaatt
     2581 agtatctgat tttggtatga gcaattactt agactttcct agctatgaag aaatggtaga
     2641 aatgtacaat gtcaacttta ccaataatga caagttgtac gaatacagaa atgaccgaca
     2701 agaaaaacac caacaaaata ttcatgccca tcacctcatt caatcatttt ctcctgaaga
     2761 taatctgaca cctgaagaaa ttaaccgcat tggttatgag accattatgg aattaacagg
     2821 aggccgtttt cgtttcatcg tagcgactca tacagacaaa gatcatattc ataatcacat
     2881 cttaatcaac gccattgact gtaattcaga taaaaagttg atatggaatt atgccttgga
     2941 acgaaacctt cgtatgattt cagaccgcat ttctaaaatg gctggggcga aaattattga
     3001 aaagcgtttc tcttaccgtg actatcaaaa atatagagcg actagccata agtttgaact
     3061 aaagcaacgt ctttattttt tgatgcagca gtcaaaatcc tttgatgatt ttttagaaaa
     3121 agcagagcaa ttacatgttc atattgattt tagtcagaag catagtcgat tcatgatgac
     3181 ggatcgggca atgacaaaac caattcgagg acgtcaactc agtaaacgag atttatatga
     3241 tgaagatttt tttagaatgc attttaccaa gcaagagatt gcaagtcgtt tagaattttt
     3301 gttgaactgt gtcaattctt tagaagggtt actaacaaaa tcaaaagaat tgaatctaac
     3361 cattgactta aaacaaaaaa atgtaatctt tatacttgaa gaaaatggaa agcaattcag
     3421 tctgagtcat aaaaaaataa gtgatgagaa attatatgat gtcaattttt ttcaagatta
     3481 ttttaaaaat aaggaagtag gtgtttcaga aggaatagaa aatctacagg cacagtaccg
     3541 tgcttttcaa gaagaacgag ataaggagaa ggtatctact gaagaaattg aggaagcctt
     3601 tgagacattt aaggaaaaac gagatgccgt tcatgaattt gaagtaaaac ttacagaaca
     3661 ccaaattgag aagttagttg atgaggggat ttatatcaaa gtgtcctttg gtataaatca
     3721 gagtggtctt attttcattc ctaactatca actggatatt atggaagaag aaaatcagaa
     3781 aaaatataaa gtctacattc gtgagacaac ctcatatttt gtctataaca aagaacattc
     3841 ggataagaat cagtatatca aagggagaac cttgattagg cagctaacca acgatagtcg
     3901 agtaatacca tacagaagac cgactgttga aagacttcaa gaaaagattt ctgagattag
     3961 cctcttgatt gagttaactg agacagataa gaaataccaa gacattaaag acaacttggt
     4021 ttccgaaata gcagagctag atataaaact gactcaaaca aatgaaaaaa ttgccacctt
     4081 aaataagatg gcggaagtac ttatcaattc taagagtgaa ggttcgggta gccaaaaact
     4141 agctaggcat gaattttcta aattgaacat gacagaatca acaactttag aacaagtcaa
     4201 tgaagaactt ttgaagttac aacaggaatt tggtaatgtt cttgatgagt atgagaaaac
     4261 aataagaaag cttggacaat tatttaaggt ttttgatgag tgtatcaata aagaaattat
     4321 gaatgaaata taaatcagac tgaagacaaa ctcaaatttt tttggatatc ttttctgttt
     4381 atggttgcca atatcggttt aacttctaaa acaaacatta ataaaaatgc attcaaagac
     4441 gattttacct attttacgat tacgcttcga ccccaaatca ttaaagttgt ctatgctcta
     4501 tcattgcatc actggacttg tcaagagtta agataattcg gagtccactg aaaaagtcat
     4561 cgtatgatgg tatactaaag atgaggtgat ggtatgcttg ataatcgatg ttagtcccta
     4621 ttctactctg tgtgatattg ttgttcccaa aactcatttt ttacgacagc taatggaact
     4681 ctgtgatttt agttttattt atgacgagct ggaaaagaat tatcaacctg acttcggatg
     4741 tcgttcctac tctctcctta tcatgatgtt caagtatctc ttattaaaag acatctataa
     4801 gttgtccgat gtggatgtgg tggagcgctc cttttctggt atgaccttca aatacttcct
     4861 tggtctagct cctgttattg aaccgtcctc attgactaaa ttccgaaaac ttcggaacaa
     4921 agatgaacga ttacttgatt tgctcatcgc taaatctgtt cagattgcga tagagctcgg
     4981 tctgattaaa agtaacattc tcattgtgga tgcgactcat accaaagttc attacaatca
     5041 caagaaacct caagaagtcc tccgagaacg ctcaaaagcc ttgcgtaaaa cgatttatca
     5101 gtattcggaa tatatcaagg cagaatttcc tagtaagcct caggaagata ctctagtagc
     5161 tgaattaaga tatacacaag aagtaatatc agtccttgag aagcatgacg aattgactgg
     5221 aataccagct atctcacaaa attcaattac cttaaagaag ctgtagagga tgacttagag
     5281 cacttggaat cctctgtcaa agaagaagca agaattggac ataagtcagc cgatagttcc
     5341 ttttacgggt acaaagagca ttttgccatg accgatgaac ggattattac tgcctgtgtg
     5401 gtgacatcgg gtgaaaaaag tgatggtcct gttttagaag aactctatca caaatctaag
     5461 gataatggcg tgacgattga agctattgtt ggagataggg cctactctgg gaaggataat
     5521 atgcaattta ccaagaaaga acgtgtgcat tgagtcgcta ggccatatcc aactatttca
     5581 aaaggctttc gtaggaagga agatgagttt ttctataaca aggacgcagg tctctttgtt
     5641 tgtccagaag ggcatatggc actaaagaag gaaaagacag gaagaaggac ggctcaggaa
     5701 acccactatt ttgacatcaa gcactgtcaa atatgccctt caaaagtggg ctgttataaa
     5761 gaaggggcta agtctaagac ttatttgata ccccttaaga gcgatgaaca tattttccag
     5821 aagaggtttc aggaagcgcc ctattttaaa gaaaaggcca aacatcgcta caagatagaa
     5881 gccaaaaatg cggaacttga aaacagacat ggtcttaatg tagctagagc accaggtctt
     5941 ttaaacatgg agttacaagc cgccacaacc atatttgtgg ttaatatgaa gaggattata
     6001 actctaataa accaaaaata aggaaaagca aagaggaatc tatccaagca ggagatagat
     6061 ccctcttttt tcattttagt tgaactgtag agcttacttt ttcagtggac tcgatgatta
     6121 gtgactattt ttttcaaact ctattagtta ttggtaccct aatgccgaat ggagatattt
     6181 aggattgtaa tagatttcaa tatatttaaa gatttcgttc aatagttgcg aaattggcat
     6241 cattgacaag ttctcttttt atgttttgta aaaggattcc atgggtgcat tatcatatgg
     6301 attgcctttt cgactcaggc tagacttgca tcttttctgt ttaaggagtt cttgaaatct
     6361 agctccagta tattgagatc cttgatcggt atggccgact agttcttatt tgagattttc
     6421 tctatgataa gcttgattga aaacattcgt taccaactta tcttgcattc gatttcccat
     6481 tgcctaacca acaatttttc tgctataaac atatatataa tgataaataa agagtacctg
     6541 cttttgtcgg aatataagtt aaatccccca gccagatttc atttttacct tttgtttgaa
     6601 aacactgatt aatcaaattg ggtcgtgtta atgaggaatg ccgacggcta tagtacttgt
     6661 atttatagcg gattccttta gcatagagac aaa
//
LOCUS       DAVKMJ010000076         6655 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000076 DAVKMJ010000000
VERSION     DAVKMJ010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6655
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.076"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(73..165)
                     /locus_tag="VW348_002029"
                     /pseudo
     CDS             complement(73..165)
                     /locus_tag="VW348_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(201..484)
                     /locus_tag="VW348_002030"
                     /pseudo
     CDS             complement(201..484)
                     /locus_tag="VW348_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
     gene            complement(474..614)
                     /locus_tag="VW348_002031"
     CDS             complement(474..614)
                     /locus_tag="VW348_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002875407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEU9746871.1"
                     /translation="MVSCHSSLRSYIAEPILKQAGFTVQNLDGAYSLYKMVNPEGVEY
                     GN"
     gene            706..1470
                     /locus_tag="VW348_002032"
     CDS             706..1470
                     /locus_tag="VW348_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEU9746872.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWSTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            2035..3414
                     /locus_tag="VW348_002033"
     CDS             2035..3414
                     /locus_tag="VW348_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEU9746873.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLV
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            3428..4093
                     /locus_tag="VW348_002034"
     CDS             3428..4093
                     /locus_tag="VW348_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEU9746874.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            4228..4302
                     /locus_tag="VW348_002035"
                     /pseudo
     CDS             4228..4302
                     /locus_tag="VW348_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            4448..4987
                     /locus_tag="VW348_002036"
     CDS             4448..4987
                     /locus_tag="VW348_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9746875.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDVFVTNFVYEKEGQSRKKSMSYDSVLPVRQIFGWDQVGNFSKGQ
                     YTMMHSLIYRTDLLRASQF"
     gene            5054..5464
                     /locus_tag="VW348_002037"
     CDS             5054..5464
                     /locus_tag="VW348_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEU9746876.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLIDQLD
                     LSQVSHPKMREYLLNHIELTTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            5580..>6655
                     /gene="pavB"
                     /locus_tag="VW348_002038"
     CDS             5580..>6655
                     /gene="pavB"
                     /locus_tag="VW348_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEU9746877.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKASDKA"
BASE COUNT         1813 a         1283 c         1525 g         2034 t
ORIGIN      
        1 aaaacagtgt tttgagctga cttcgtcagt tccatccaca accttaaaac agtgttttga
       61 gctgacttcg tcagttccat ccacaacctt aaaacagtgt tttgagcagc ctgcggctaa
      121 cttcctagtt tgcactttaa ttttcattga gtattacttc atcttctcat gaaattgagt
      181 ttttgcccag ctcctcttga ttattctact tgaccgggcc aagcattcat accaccttct
      241 acgttggtaa cggtgaggcc ttgggagctg agaaattggc aggtagatgc agagcggact
      301 cctccgtgac aaatgacata gtattcatgg tcaggtttga gttctttgta gccttgctct
      361 aaggtattta tggaagattt ttgggtcctg cttggaattc atgtgcttca cggacatcga
      421 taagttccag attttcattt tgatattttc tataaaagtc agccatgctg atactagttt
      481 ccatattcta ctccttctgg gttaaccatt ttgtatagtg aataagcgcc gtcaaggttt
      541 tggacggtaa atcctgcttg cttgaggata ggctctgcga tatagctgcg caaactactg
      601 tggcaactga cgatgtaggc ttgtttttct cctcagttca tcagcttcct ccttgacact
      661 cggtcagatt ttgatacaat agtacaaaat tagaggaggt gggctatgat tcagaaacat
      721 gcgattccca ttttagagtt tgatgataat cctcaggcgg ttatcatgcc caatcacgag
      781 gggttggatt tgcagttgcc aaagaagtgt gtctatgctt ttttaggtga ggagattgac
      841 cgctatgcga gggaagtagg ggcgaactgt gttggcgaat tcgtttctgc taccaagacc
      901 tatccagtct atgtcatcaa ctacaagggt gaggaggtct gtctggctca ggctcctgtt
      961 ggctccgctc cagcagccca gtttatggat tggttgattg gctatggtgt ggagcagatt
     1021 atctctactg ggacctgtgg tgtcctagct gatatagagg aaaatgcctt tctagtccct
     1081 gttcgcgctc tgcgagatga aggagccagt taccactatg tggcaccttc tcgttatatg
     1141 gaaatgcagc cagaggctat tgctgccatt gagcgagttt tggatgatag agggattcct
     1201 tatgaagaag tcatgacctg gtccacagat ggtttttacc gagaaacggc tgaaaaggtg
     1261 gcttatcgta aggaagaagg ctgtgctgtt gtggagatgg agtgttctgc tcttgcggca
     1321 gtagctcaat tgcgtggagt tctctggggt gaattgttgt tcacagcaga ttctctagcg
     1381 gacttggacc agtacgacag tcgtgactgg ggctcggaag cttttaataa ggcactagaa
     1441 ctgagtttag caagtgttca ccacctttag ttgtactggc aaaggatttg ttttatcata
     1501 aaatgtctag ctcatacttt tcaaaaatat gtttaaacga ggtcaccttc ctcttgtcct
     1561 aggcatgttg aggttgggaa aaatctttaa aatcagaaaa acgtatcata tcaggtgatg
     1621 aaaattttga tactatgcgt tttatgttgg taagatttag agtgagatga aatgatactc
     1681 ttcgaaaatc tcttcaaacc aggtcagctt caccttgccg tatagatgtt actgacttcg
     1741 tcagttctat ccacaacctc aaaacagtgt tttgagcaac ctgtgactag ctttctaagc
     1801 gatgccttgg ttctcattgc ctataatcaa aaagagaaat tttctcctga aaagcatata
     1861 gagtagctgg cgttaaaagc tcctgtcttg cttttttgac ctatagtcac atctatcaag
     1921 tattgttctt gcctaagcta tcaataaaaa ggtggcattt tttaggcttg gtgttagtag
     1981 attttgcctt atcctatcta agtcatttcg aactttttat ggtacaatgg aaacatgtta
     2041 ttcaaattat ctaaggaaaa aatagagcta ggcttatctc gtttatcgcc agcccgtcgt
     2101 atttttttga gttttgcctt ggtcatttta ctaggctctc ttcttttgag cttgcccttt
     2161 gtccaagttg aaagctcacg agcgacttat tttgatcatc ttttcactgc tgtctctgca
     2221 gtctgtgtga caggtctctc aacccttcca gtagctcaca cctataatat ctggggccaa
     2281 ataatctgtt tgctcttgat tcagatcggt ggtctagggc tcatgacctt tattggggtt
     2341 ttctatatcc agagcaagca aaagcttagt cttcgtagcc gtgcaactat tcaggatagt
     2401 tttagttatg gagaaactcg atctttgaga aagtttgtct attctatttt tctcacgacc
     2461 tttttggttg agagcttggg agctattttg cttagttttc gccttattcc tcaacttggc
     2521 tggggacgtg gtctttttag ttccattttt ctagcgatct cagccttctg taatgccggt
     2581 tttgataatt tagggagcac cagtttattt gcttttcaga ccgatttact ggtcaatctg
     2641 gtgattgcag gcttgattat tacaggcggc cttggtttta tggtctggtt tgatttggct
     2701 ggtcatgtag gaagaaagaa aaaaggacgt ctgcactttc atacgaagct tgtactatta
     2761 ttgactatag gtttgttgtt atttggaaca gcaactactc tctttcttga gtggaacaat
     2821 gctggaacga ttggcaatct ccctgttgcc gataaggttt tagttagctt ttttcaaaca
     2881 gtgacgatgc gaacagctgg cttttctacg atagattata ctcaggctca tcctgtgact
     2941 cttttgattt atatcttaca gatgtttcta ggtggggcac ctggaggaac agctggggga
     3001 ctcaagatta cgacattttt tgtcctcttg gtctttgcac gaagtgagct tctaggcttg
     3061 cctcatgcca atgttgcgag acgaacgatc gcgccgcgaa cggttcaaaa atcctttagt
     3121 gtctttatta tctttttgat gagcttcttg ataggattga ttctgctagg gataacagcc
     3181 aaaggcaatc ctccctttat ccacctcgta tttgaaacca tttcagctct tagtacagtt
     3241 ggtgtaacgg caaatctgac tcctgacctt gggaaattgg ctctcagtgt tatcatgcca
     3301 cttatgttta tgggacgaat tggtcccttg accttgtttg ttagcttggc agattaccat
     3361 ccagaaaaga aagatatgat tcactatatg aaagcagata ttagtattgg ttaagaaagg
     3421 aaagagcatg tcagatcgta cgattggaat tttgggcttg ggaatttttg ggagcagtgt
     3481 cctagctgcc ctagccaagc aggatatgaa tattatcgct attgatgacc acgcagagcg
     3541 catcaatcag tttgagccag ttttggcgcg tggagtgatt ggtgacatca cagatgaaga
     3601 attattgaga tcagcaggga ttgatacctg cgataccgtt gtagtcgcga caggtgaaaa
     3661 tctggagtcg agtgtgcttg cggttatgca ctgtaagagt ttgggggtac cgactgttat
     3721 tgctaaggtc aaaagtcaga ccgctaagaa agtgctagaa aagattggag ctgactcggt
     3781 tatctcgcca gagtatgaaa tggggcagtc tctagcacag accattcttt tccataatag
     3841 tgttgatgtc tttcagttgg ataaaaatgt gtctatcgtg gagatgaaaa ttcctcagtc
     3901 ttgggcaggt caaagtctga gtaaattaga cctccgtggc aaatacaatc tgaatatttt
     3961 gggtttccga gagcaggaaa attccccatt ggatgttgaa tttggaccag atgacctctt
     4021 gaaagcagat acctatattt tggcagtcat caacaaccag tatttggata ccctagtagc
     4081 attgaattcg taaagaggga tgacccctct tttttgatgc ctaagatggc aaatagagac
     4141 agaagcccct tgtcttctag taaaagttct tcaaaggctg gactttatgg taaaatagaa
     4201 agaagtgaca agagagagta atactcaatg aaaatcaaag atcaaactag gaaactagct
     4261 acgggctgct caaaacactg ttttgaggtt gcagatagaa ctgacgaagt cagctcaaaa
     4321 cactgttttg aggttgcaga tagaactgac gaagtcagta acatctatac ggcaaggcga
     4381 cgttgacgcg gtttgaagag attttcgaag agtataagaa aaaatcagtc ccctaaagga
     4441 gtagattatg aagttattgt ctatcgcaat ttctagctat aatgcagcag cctatcttca
     4501 ttactgtgtg gagtcgctag tgattggtgg tgagcaagtt gggattttga ttatcaatga
     4561 cgggtctcag gatcagactc aggaaatcgc tgagtgttta gctagcaagt atcctaatat
     4621 cgttagagcc atctatcagg aaaataaatg ccatggcggt gcggtcaatc gtggcttggc
     4681 agaggcttct gggcgctatt ttaaagtagt tgacagtgat gactgggtgg atcctcgtgc
     4741 ctacttgaaa attcttgaaa ccttgcagga acttgagagc aaaggtcaag aggtggatgt
     4801 ctttgtgacc aattttgtct atgaaaagga agggcagtct cgtaagaaga gtatgagtta
     4861 cgattcagtc ttgcctgttc ggcagatttt tggctgggac caggtcggaa atttctccaa
     4921 aggccagtat accatgatgc actcgctgat ttatcggaca gatttgttgc gtgctagcca
     4981 gttctaactg cctgaacata ctttttatgt cgataatctc tttgtcttta cgccccttca
     5041 gcaggtcaag accatgtact atctgcctgt cgatttctat cgttatttga ttgggcgtga
     5101 ggaccagtct gtcaatgagc aagtgatgat taagtgcatt gaccagcaac tcaaggtcaa
     5161 tcgactcttg atagaccaac ttgatttgtc ccaagtgagt catcccaaaa tgcgagaata
     5221 tctgctgaat catattgaac tcacgacggt gatttccagt accctgctca accgatctgg
     5281 aacagcggag catctggcaa aaaaacgcca attgtggacc tatattcagc agaaaaatcc
     5341 agaagtcttt caggctattc gtaagaccat gttgagccgt ttgaccaaac attctgtctt
     5401 gccagatcgc aaactgtcca atgtcgtcta tcaaatcacc aaatctgttt atggatttaa
     5461 ttaatataag tgttttataa gagggattta agaaaaattt taactttttc ttagtccttt
     5521 ttaatttcag gagattatac tagagtcatc aaataaagaa agactctaag gagaatccta
     5581 tgaaattcaa tccaaatcaa agatatactc gttggtctat tcgccgtctc agtgtcggtg
     5641 ttgcctcagt tgttgtggct agtggcttct ttgtcctagt tggtcagcca agttctgtac
     5701 gtgccgatgt ggtcaatccg accccaggtc aagtcttacc tgaagagaca tcgggaacga
     5761 aagagggtga cttatcagaa aaaccaggag acaccgttct cactcaagcg aaacctgagg
     5821 gcgttactgg aaatacgaat tcacttccga cacctacaga aagaactgaa gtgagcgagg
     5881 aaacaaactc ttctagtctg gatacacttt ttgaaaaaga tgaagaagct caaaaaaatc
     5941 cagagctaac agatgtctta aaagaaactg tagatacagc tgatgtggat gggacacaag
     6001 caagtccagc agaaactact cctgaacaag taaaaggtgg agtgaaagaa aatacaaaag
     6061 acagcatcga tgttcctgct gcttatcttg aaaaagctga agggaaaggt cctttcactg
     6121 ccggtgtaaa ccaagtaatt ccttatgaac tattcgctgg tgatggtatg ttaactcgtc
     6181 tattactaaa agcttcggat aatgctcctt ggtctgacaa tggtactgct aaaaatcctg
     6241 ctttacctcc tcttgaagga ttaacaaaag ggaaatactt ctatgaagta gacttaaatg
     6301 gcaatactgt tggtaaacaa ggtcaagctt taattgatca acttcgcgct aatggtactc
     6361 aaacttataa agctactgtt aaagtttacg gaaataaaga cggtaaagct gacttgacta
     6421 atctagttgc tactaaaaat gtagacatca acatcaatgg attagttgct aaagaaacag
     6481 ttcaaaaagc cgttgcagac aacgttaaag acagtatcga tgttccagca gcctacctag
     6541 aaaaagccaa gggtgaaggt ccattcacag caggtgtcaa ccatgtgatt ccatacgaac
     6601 tcttcgcagg tgatggtatg ttgactcgtc tcttgctcaa ggcatctgac aaggc
//
LOCUS       DAVKMJ010000077         6190 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000077 DAVKMJ010000000
VERSION     DAVKMJ010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6190
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.077"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            83..1837
                     /locus_tag="VW348_002039"
     CDS             83..1837
                     /locus_tag="VW348_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9746878.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISALLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNINNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            1821..3542
                     /locus_tag="VW348_002040"
     CDS             1821..3542
                     /locus_tag="VW348_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9746879.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDVK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            3553..4137
                     /locus_tag="VW348_002041"
     CDS             3553..4137
                     /locus_tag="VW348_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEU9746880.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            4137..4832
                     /locus_tag="VW348_002042"
     CDS             4137..4832
                     /locus_tag="VW348_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEU9746881.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKIAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VAGLIVGGLIWLK"
     gene            4820..6184
                     /locus_tag="VW348_002043"
     CDS             4820..6184
                     /locus_tag="VW348_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9746882.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGSGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDESSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKNSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT         2252 a          789 c         1159 g         1990 t
ORIGIN      
        1 gtataataga aaagcaatga tagatattat caattaagcg aatttatatc taaaagggat
       61 attaaagaaa ggagatatgc ttatgaagat ttacaaaaaa ctatttgctt atgtccaaga
      121 taagaaatat cttggggttt tggccataat tttttctgct atatctgctc tacttacagt
      181 atatggatat tatttaatct acaaatttct agataagtta ataattaatt caaatttatc
      241 cggtgcagag agtatagcat taaaatctgt tattacacta acaagtggag cgatatttta
      301 ttttgtctca ggaatgtttt cacacatctt gggatttagg cttgaaacaa atttaagaaa
      361 aaggggaatt gatggcttag agaaagcaag ttttaggttc tttgacttaa atccatctgg
      421 tcaaataaga aagatcatag atgataatgc agcacaaact catcaggtgg tagcacacat
      481 gattcccgat agttctcagg caataatcac acccgtactt gtacttgcac ttggctttat
      541 agtaagtata agagttggca taattttgct tgctcttact ataattggcg gcttaatttt
      601 aggggcaatg atgggcgagc aagaatttat gaagatatac caagaatccc tatctaaact
      661 aagtgctgaa actgttgagt acgtgagagg aatgcaagtt gtaaaaatat ttaaagcaaa
      721 tgtagagtct tttaaaagct tttataaggc gataaaagat tactcaaagt atgcttatga
      781 ttattcccta tcttgtaaaa ggccttatgt tttgtatcaa tggttatttt ttggactgat
      841 tgcaatttta attattccta tagtttattt tatgactagc ttagctagcg caaaggtgat
      901 tttacttgag cttatcatga ttttattttt atcaggagtt ctctttgttt cattcatgag
      961 aatgatgtgg tactccatgt atatttctca aggaaattat gcagtagata ctttagaggc
     1021 gctttacgaa gatatgcaaa aagacaaatt agtgcatggt aatatcaata attttaaaaa
     1081 ctataatata gaatttgaga atgttagctt tgcttataat gataaagctg tcattgaaaa
     1141 tttatccttt aatttagaag aaggaaagtc ctacgcactt gtcggttcat ctggatcagg
     1201 caaatcaaca gtagcaaaac ttatatcagg tttttataat gttaataaag gaagcataaa
     1261 gataggcggg atagcaataa gtgaatattc tgacgaagcc ttaattaaag ccatttcctt
     1321 tgtttttcaa gattcaaaat tattcaagaa gagcatttat gataatgtag ctttagctaa
     1381 taaagatgcg acgaaagatg acgttatgag agccttaaaa ttagcaggat gcgatttaat
     1441 attagacaaa ttcccagaaa gagaaaatac aatcataggc tcaaaaggtg tttatttatc
     1501 cggtggagaa aaacaaagaa ttgcaattgc tagagcaatt ttaaaggatt ccaaaattat
     1561 tattatggat gaagcatcag catctattga cccagataac gagtttgaat tgcaaaaagc
     1621 ttttaaaaat cttatgaagg ataaaacagt tatcatgatt gcacacaggc tatctacaat
     1681 taaagacctt gatgaaatta ttgtcatgga tagtggaaaa attatagaaa gagggtctga
     1741 caaagaatta atgtcaaaag atacaaggta taagagcctg caagagatgt ttaacagtgc
     1801 gaatgaatgg agggtttcaa atgaaagagt tttataaaaa aagatttgct cttacagatg
     1861 gaggagcaag aaatttaagt aaagcaacac tggcttcatt tttcgtttat tgtataaaca
     1921 tgcttcctgc catattactt atgatttttg ctcaggaagt tttggaaaat atgggcaaaa
     1981 gcaatggctt ttatatagta ttctcagttt tgactttgat agcaatgtat attttgcttt
     2041 ctatcgaata cgataaatta tataacacaa cctatcaaga aagtgcagat ttaagaataa
     2101 ggacagcgga gaatttatca aaattacctc tatcttactt ttctaaacat gacatttccg
     2161 acatttcaca aacaatcatg gctgatattg aaggcataga gcatgcaatg agccactcaa
     2221 taccaaaggt gggcggcatg gtactgtttt tcccattaat atctgtaatg atgctagcgg
     2281 gcaatgtcaa gatgggttta gctgtaatta ttccatctat tttaagcttt atatttatac
     2341 ctttatctaa aaaatatcag gttaatggac agaatagata ttatgatgtc ttaagaaaaa
     2401 actcagaaag ctttcaagaa aatatcgaaa tgcaaatgga gattaaagca tataatttat
     2461 cgaaggatat taaagatgac ttatataaaa aaatggaaga tagtgagaga gtacacttaa
     2521 aggcggaagt aactacaatt ttaactttgt ctatatcttc aatatttagc tttatatctc
     2581 ttgctgttgt gatatttgtc ggcgtaaatc taattattaa taaagagata aattctctct
     2641 accttatagg atatttacta gctgctatga agataaaaga ctctttagat gcatctaaag
     2701 agggcttgat ggaaatattt tatttatcgc ccaaaataga aagattaaaa gaaattcaaa
     2761 atcaagattt acaagaaggc gatgactata gcttaaaaaa atttgatatt gatctaaaag
     2821 atgttgagtt tgcctacaat aaagacgcaa aagttttaaa tggtgtaagt tttaaagcta
     2881 agcagggaga ggtcactgct ttggtaggtg caagtggctg cggtaaaaca actatcttga
     2941 aacttatatc aagactttat gattatgaca agggacaaat cttaatcgat gtcaaagata
     3001 taaaagaaat atcaacagaa tctctttttg ataaggtctc tatagttttc caagatgtgg
     3061 ttctctttaa tcaaagcgtt atggaaaata ttagaatcgg aaagcaagat gcaagtgacg
     3121 aagaggttaa aagagcagca aaacttgcaa attgcacaga ttttatagaa aaaatggata
     3181 aaggtttcga tacagttatt ggtgagaacg gagctgagct atcaggagga gaaagacaaa
     3241 gattatcaat agccagagcc ttcttaaaag atgcgccgat attgatctta gatgagataa
     3301 cagcaagcct tgatgttaac aacgagaaaa agattcaaga gtctttaaat aatttagtta
     3361 aagataaaac tgttgtaatc atttcacata gaatgaaatc catagaaaat gcagacaaga
     3421 tagtagttct tcaaaacgga agagtagaaa gcgaaggtaa gcatgaagag cttttacaaa
     3481 aatcaaaaat ttacaaaaat ttaatagaaa agacaaaaat ggcagaagaa tttatttatt
     3541 aggaggacta caatggataa taaaaaatta aaagtaaaag atttagtaag tatcggtgtt
     3601 tttggcgtaa tttattttgc cttcatgttt ggagttggta tgatgggctt gattccaata
     3661 ttgttcttaa tatacccgac agtattagcc atagttgcag gaactgttgt tatgttattt
     3721 atggctaagg ttcaaaagcc atgggcacta tttatatttg gtatgatatc accacttgtg
     3781 atgtttgcag ctggtcatac ctacgtagtt gtggttttat cacttatagt aatgataata
     3841 gcagaattaa ttagaaagat tggtaattat aattcattta aatacaatat gctttcttat
     3901 gcaatcttca gcacatggat atgtagctct ttaatgcaaa tgcttttagc aaaagaaaaa
     3961 tatatggagt ggtctttgat gacgatggga aaagattatg ttgatgtatt agaaaagtta
     4021 ataacttatc ctcacatggc tttagtagcc ttaggtgctt tcttaggagg aattcttgga
     4081 gcatatatag gcaaggctct attgaaaaaa cactttgaaa aagcaggcat cgtataatgc
     4141 ctactttttc ttcaaatgct ccctttaatc ccaatccgat ctctaagata ttagtcgtat
     4201 ttatcacagg cttaactgtt atgcatagca taaacatccg ttttgagctg gcaattgttt
     4261 gtcttattgg tattttgctt tatttgaatg gatacaaaaa aacacttttc aaatggatta
     4321 tattgtgtgg gatactttac tccttgccta attttatggt gttatctgaa ttaaacccta
     4381 tagttaagat gtttttgagt atacctattg ttattagaat gtttatttta ccatttatgg
     4441 cagcaagctt tatgataaag acctcggatg taggcgcaat aatttcatcg atggataagc
     4501 ttaagatttc aaagaatgta tccataccta ttgcggttat gtttagattc ttcccatctt
     4561 ttaaggagga gaagaaaaac atcaaaatag ctatgagagt aagagggata aattttaaaa
     4621 acccagtcaa atatcttgaa tatgtttctg tgccactact cattatatca tctaatatat
     4681 cagatgacat tgcaaaagcg gcagaaacaa aggcaataga aaatccaatt gccaagacca
     4741 gatacattcg cgtaaagata cagctaattg attttgttta tgttttagcg gttgctggac
     4801 ttattgtggg aggcttaata tggttgaaat aaaaaattta agtcttgatt atggtgaaga
     4861 gcatatatta gatgatatat cactatccat agccgaggga gagtgcgtgc tatttacagg
     4921 aaaaagtgga agtggtaagt catctttaat aaattcaatc aatggactag ctgtaaggta
     4981 tgataacgca aagacaaagg gcgaaataat tattgatggt aagaatataa aaaatttgga
     5041 actttatcaa atctcaatgc ttgtttcaac tgtttttcaa aatcctaaga catatttttt
     5101 taatgtcaat acgacattag aattattatt ttatttggaa aatatcggtc ttgcaagaga
     5161 agagatggac aggcgtttga aggatatgct tgagatattc ccgataaaaa atcttttgaa
     5221 cagaaatata tttaatctat ccggcggtga aaaacaaatt ctttgcattg cagcttctta
     5281 tatagcaggt acaaagatta tagttatgga tgagtcttca tcgaatttag atattaaaag
     5341 cataagtgtt ttggcaaaga tgctaaagat attaaaagag aaaggcataa gcataattgt
     5401 tgcagagcat agaatttatt atttgatgga catagttgac cgtgtatttt taatagataa
     5461 aggaaagctt aaaaaaactt atactagaag tgaattttta aagctagata aaaatgaatt
     5521 aaatgcttta agtttaagag ataaagaatt aagtaaatta aaagttcctt atttaaaaga
     5581 aggtggagag tatcagataa aaaatcttag ctacaaattt actgatgatg agtgtttaag
     5641 cttaaaagat atttcgttca agcttgggaa aatttatggc ataataggat ccaacggacg
     5701 aggaaaatca acgcttttaa gatgtttaat aggtcttgag aaaaaatcaa aagaagaaat
     5761 ttattttaag ggagagaagc tatctaaaaa agaaagactc aaaaactctt cacttgttat
     5821 gcaagatgta aatcatcaat tattcacaga tgaagtattc aacgagctta gattaggagt
     5881 aaagaatttt gatgaagaaa aggcgaaaat cattttaaaa gatttaggcc tggacgaatt
     5941 tattgaaagg catccgatga gtttatcagg agggcaaaag caaaggcttg caatagcatc
     6001 tgttatgtgc aagaattctc catttgtctt ttttgacgaa ccttcaagtg gtatggatta
     6061 ttccaatatg ataaaaatat ctgaactgat taataagtat aaaaccatgg ataaaataat
     6121 ttttattgtt tcccatgata tagaattttt aaatgaagtg gcagatgaaa tttttgaatt
     6181 gtaaaataga
//
LOCUS       DAVKMJ010000078         6001 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000078 DAVKMJ010000000
VERSION     DAVKMJ010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6001
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.078"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            67..309
                     /locus_tag="VW348_002044"
     CDS             67..309
                     /locus_tag="VW348_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEU9746883.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            311..565
                     /locus_tag="VW348_002045"
     CDS             311..565
                     /locus_tag="VW348_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEU9746884.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHWRDIY"
     gene            612..1264
                     /locus_tag="VW348_002046"
                     /pseudo
     CDS             612..1264
                     /locus_tag="VW348_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
     gene            complement(1524..2510)
                     /locus_tag="VW348_002047"
     CDS             complement(1524..2510)
                     /locus_tag="VW348_002047"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEU9746885.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            2704..5172
                     /gene="gyrA"
                     /locus_tag="VW348_002048"
     CDS             2704..5172
                     /gene="gyrA"
                     /locus_tag="VW348_002048"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEU9746886.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            5172..5915
                     /gene="srtA"
                     /locus_tag="VW348_002049"
     CDS             5172..5915
                     /gene="srtA"
                     /locus_tag="VW348_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEU9746887.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         1897 a          982 c         1303 g         1819 t
ORIGIN      
        1 tttatattga ctgaacacct aaaaagtaat acaatggtgt taccattaaa aaagggagca
       61 caaaagatga ctactattac attaaaagtt tctgaagctg ataaaacatt tatgaaagca
      121 atggctaagt ttgaaggagt ttccctttcg gaacttattc gcaccaaaac tcttgaagcc
      181 ctagaagatg aatacgatgc tcgtgtggca gatttagcct atcaagagta tttagaagac
      241 ttggaaaaag gagttgaacc cattacttgg gaagaaatga tgcatgattt aggcttgaag
      301 gatgaataat ttgtataaat tagttccaac aagacgtttt atcaagcaat tgaaaaaatt
      361 ggaccgttat acgcagaagc taattacaaa ctatttacaa accaatgttt tggaagaccc
      421 aagacgacac ggaaaggctt tggttggtaa tcgcgttggt caatggcgct atagaattgg
      481 taattatcga gttatcgtac aaattgtaga tgatgaatta gttgttgcta ctctagaagt
      541 tggtcattgg agagatattt attgaattaa agctgagtaa taacagtata gaaagtaagg
      601 atagtaaaaa tttgaataaa aaatggttat ttgcagatta ttatgatata acaattattt
      661 tacttgcttt aatctctgtt attctggtat tacttggatt tgctgagatg attgatttgg
      721 acaatccgcc ttatagtatt attgatttag taatctgggg tgtttttgta attgattata
      781 gttggcgctt ttttattact aaaagaaaat ggcgctttat tcttgaaaat atttttgatt
      841 tattgactat tctcccttta aatgctattt ttacagtgtt tcgattagga cgtatcttcc
      901 gcttagcaag gctgacaaaa ttactgaaac tgactcgttt acttagaata attggactta
      961 caggtaaatt agaaagaaaa attagtagat tcttacgaac aaatggattg atttatatct
     1021 tgtatgttaa tatctttatt gttctagtag ggagttcgat tttatccgtt gttgaagaaa
     1081 aatccttctc agatagtctt tggtgggctc ttgtgacagt aactactgtt ggttatggtg
     1141 atattgttcc agtttccctt tttgggaaga cgaattatcg agccaaagaa tattaataga
     1201 gaaacaatcc gagaagatag aagaactgca tcggatgata caagatttgc ttgaaaaaac
     1261 ataataaaaa taaagatgag acaaagtttg agttgaggag aaatcaagta agttttgaca
     1321 caatagaacg catattatca ggtataaaaa cttgatacta tgcgttttat agagaaatga
     1381 aataaaatct gaacaaatca attaggaatt taaagcattt tataacaacg ttttagagta
     1441 atggggggct atttcaactt caacctacta taatacagaa aaaaacaact ccctgataat
     1501 tcaaggagtt gtctatagtt aaattagttt ttagaagctt cttggaattc tgggtttttc
     1561 catgcttcgt caatgatagc ttgcaattct ttagcagatg cttgcatttt ttgagtttct
     1621 gcgtcgttca atgggatatt tactggacga acaataccat gtgcaccaac aacagctggt
     1681 tgaccgataa agacgttctc aactccgtat tgaccttctt ggaatactga aagtggaagt
     1741 actgcatttt catcgtcaag gattgcttta gtgatacgag caagggctac tgcgataccg
     1801 tagtatgttg cacctttttt gttgatgatt gtgtaggctg catcacgaac accttcgaac
     1861 aattcaatca attcagcttc ttgaacattt tgagtatctt taaggaattc ttcaaggttt
     1921 acaccagcga tgttagcgtg tgaccaaaca gcgaactcag agtcaccgtg ttcacccatg
     1981 atgtaggcgt gaactgaacg agcatctacg tccaattttt cagcaagtgc ttgacggaaa
     2041 cgagctgagt caagtgaagt acctgaaccg ataacgcgtt ctttagggaa accagagaat
     2101 ttccaagttg agtaagtcaa aacgtcaact gggttagcag caacaaggaa gatacctttg
     2161 aaacctgatt caacaacttg agttacgatt gatttgttga tagcaaggtt tttacctaca
     2221 aggtcaagac gagtttcacc tggtttttga ggcgcacctg cagtgatcac aacaaggtca
     2281 gcgtctgcac agtcagagta ttgagctgca tagatttttt taggtgaagt gaaggcaagg
     2341 gcgtgactaa ggtcaagcgc atcaccaaca gctttttcat gcaattgtgg aatttcgata
     2401 attccaagct cttgtgcaat tccttggtta acaagtgcaa aagcgtaaga tgaacctaca
     2461 gcaccatcac cgacaaggat aacttttttg tgttgtttag ttgaagtcat tgttttaaac
     2521 atctccttaa ttttattagg ggattttccc tagacaactt cattctatca cttttaaaaa
     2581 actttgtcac gaatatgcct tatagttctc gatgtaaacg ttttagtggt ttagaggctg
     2641 aaatagatgg gaatttatgg tataatgttg ttacttacta attgtgaaat gaggcattta
     2701 ttaatgcagg ataaaaattt agtgaatgtc aatctgacaa aggagatgaa ggcaagtttt
     2761 atcgactacg ccatgagtgt tatcgtagcg cgagctcttc ctgatgttcg agatggctta
     2821 aaacctgttc accgtcgcat tctttacgga atgaatgaat tgggtgtgac cccagacaaa
     2881 ccccataaaa aatctgctcg tattacaggg gatgtcatgg gtaaatatca cccacacggg
     2941 gattcctcta tttatgaagc catggtccgt atggctcaat ggtggagcta ccgttacatg
     3001 cttgtagatg gtcatgggaa ttttggttcc atggatggag atagtgctgc cgctcaacgt
     3061 tataccgagg cacgtatgag caagattgct ctggaaatgc ttcgtgatat caacaaaaat
     3121 acagttgatt tcgttgataa ctatgatgcc aatgaacggg aacccttggt cttgccagcg
     3181 cgttttccaa accttttggt taatggagca actggtatcg cggttgggat ggcaaccaat
     3241 attccacctc ataatctggg tgaaaccatt gatgcagtga agttggtcat ggataatcct
     3301 gaagtgacta ccaaggactt gatggaagtc ttgcctggac cagattttcc aactggtgct
     3361 cttgtcatgg ggaaatcagg tatccataag gcttatgaaa caggtaaagg ttcgattgtc
     3421 ctacgttctc gtacagagat tgaaacgact aagactggtc gtgagcgcat cgttgtaaca
     3481 gaatttcctt acatggtcaa taaaaccaag gtgcatgagc atattgttcg cttggttcag
     3541 gaaaaacgca ttgagggtat cacagcagta cgtgatgagt caaaccgtga aggtgttcga
     3601 tttgttattg aagtcaagcg cgacgcctca gccaatgtta ttctcaataa cctcttcaaa
     3661 atgacccaaa tgcaaaccaa ttttggtttc aatatgctcg ctatccaaaa tggtataccg
     3721 aaaattttgt ctcttcgtca gattttggat gcttatatcg agcaccaaaa agaagtggtt
     3781 gttcgtcgta cacgttttga taaggaaaaa gcggaagcgc gcgctcatat cttagaaggt
     3841 ctcttgattg cgctagacca tatcgacgaa gtgattcgta tcatccgtgc tagtgaaacg
     3901 gatgcggaag ctcaagctga gttgatgagc aagtttaagc tttctgaacg tcaaagtcaa
     3961 gctatccttg atatgcgtct tcgtcgtttg acaggtttgg aacgcgataa gattcaatct
     4021 gagtatgatg acctcttggc tctgattgcg gatttagcag atattcttgc taagcctgaa
     4081 cgtgtttctc aaattatcaa agacgaattg gatgaagtta aacgtaaatt ttctgataag
     4141 cgccgtacag agttgatgat tggacaggtc ttgagtctcg aggatgagga cttgattgaa
     4201 gaatcggatg tcttgattac cctttctaac agaggctaca ttaagcgttt ggatcaggac
     4261 gagttcactg ctcaaaaacg tgggggtcgt ggtgtccaag gaacgggagt gaaagatgat
     4321 gactttgttc gtgagttagt gtcaactagc acccatgatc atctgctctt cttcacaaac
     4381 aagggacgtg tctatcgtct taaaggttat gaaattcctg agtatggtcg gactgccaaa
     4441 gggctaccag tagtcaatct cttgaaattg gatgaagacg aaagtattca gacggttatc
     4501 aatgttgagt ctgatcgcag tgatgatgct tatctcttct ttacaacccg tcacggtatt
     4561 gtgaagagaa ctagtgttaa ggagtttgcc aatattcgtc aaaatggtct caaagcgctg
     4621 aatttaaagg atgaagatga gttaatcaat gtcttgttgg cagaaggaga tatggatatt
     4681 atcattggta ccaagtttgg ttatgcagtt cgctttaatc aatcagccgt tcgtggtatg
     4741 agtcgtatcg ccactggtgt gaaaggtgtt aaccttcgtg aaggagacac agttgttggt
     4801 gccagcttga ttactgatca agatgaggtt cttattatca cagaaaaagg atatggtaag
     4861 cgtacagtcg ctactgaata cccaacaaaa ggtcgtggtg gtaagggaat gcagacagct
     4921 aaaattaccg aaaaaaatgg cttgctggcc ggtcttatga ctgttcaagg ggatgaggat
     4981 ttgatgatta tcactgatac aggtgtcatg attcgaacca atcttgccaa tatttcacaa
     5041 acaggacgtg caactatggg agttaaagta atgcgcctgg atcaagatgc tcagatagtg
     5101 actttcacaa cggttgcggt ggcagaaaaa gaagaagttg ggacagaaaa cgaaacagaa
     5161 ggtgaagcat aatgtctcaa aaaaataata aaaagaaaaa caagcgaaaa aatctgctga
     5221 caaatatcct agcaggattt ctgatattac tgtcactggc tttgattttt aatactcaaa
     5281 ttcgaaatat tttcatagtc tggaatacca ataagtatca agttagccag gtatcaaaag
     5341 aaaaattaga agaaaatcag gatacagaag gcaattttga ctttgattct gtcaaagcta
     5401 tctcttcgga agctgttcta acttctcaat gggatgctca aaaattacca gttattgggg
     5461 gaattgcaat tcctgaattg gaaatgaatt tgccgatttt taaaggactt gataatgtta
     5521 atctcttcta cggagctggt acaatgaaac gcgagcaagt aatgggagaa ggaaattata
     5581 gtctagctag tcaccatatc tttggtgttg ataatgctaa taaaatgtta ttttctcctt
     5641 tagataatgc taaaaatggc atgaagattt atctaactga taaaaataaa gtttatactt
     5701 atgaaatacg tgaagtcaaa cgtgtgacac cagatcgtgt tgatgaagtt gatgatagag
     5761 atggggtcaa tgaaatcaca ttagtaacct gtgaagacct tgctgctaca gaacgtatta
     5821 ttgtcaaagg tgatttgaaa gaaacaaaag attattcaca aacatctgat gaaatcctaa
     5881 cagctttcaa tcaaccatat aaacaatttt attaatacaa atcagtgaaa tcatggattt
     5941 cactgatttt ttaagatttt cataaaaata tagtaaaatg aaataagaat aggactaatc
     6001 g
//
LOCUS       DAVKMJ010000079         5939 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000079 DAVKMJ010000000
VERSION     DAVKMJ010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5939
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.079"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            411..632
                     /locus_tag="VW348_002050"
                     /pseudo
     CDS             411..632
                     /locus_tag="VW348_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(919..1401)
                     /locus_tag="VW348_002051"
     CDS             complement(919..1401)
                     /locus_tag="VW348_002051"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEU9746888.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(1496..2980)
                     /locus_tag="VW348_002052"
     CDS             complement(1496..2980)
                     /locus_tag="VW348_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEU9746889.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQLAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3133..4740
                     /locus_tag="VW348_002053"
     CDS             3133..4740
                     /locus_tag="VW348_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEU9746890.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDELIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLIRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            4905..5072
                     /locus_tag="VW348_002054"
     CDS             4905..5072
                     /locus_tag="VW348_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HEU9746891.1"
                     /translation="MKKRILSAGLTFTSALLLAACDQSGSDTKTYSSTFSGNPTTFNY
                     LLDYYADNIVN"
     gene            complement(5065..5586)
                     /locus_tag="VW348_002055"
                     /pseudo
     CDS             complement(5065..5586)
                     /locus_tag="VW348_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1752 a         1117 c         1322 g         1748 t
ORIGIN      
        1 aactggttcc ttttgaggta cgacgggcat gtcgtatagt aggttgaaac tagaatagta
       61 cacatctact tctaaaacat ttttagaaat cgatttgact gtcctgatcg atttgtcctg
      121 ttcttatttc attttactat atatctgagg tgtaagtcct cggtgggcac ctgttaccgg
      181 tgaacccaat agcgattccc aagcctgact atcgtgaggt agcggattaa aacggtctgg
      241 ggatagaccg ttttaagtct gacgctggaa ataagaatcg tcagaggaag ggatagcgaa
      301 ctcgtggctc tacgaacagg aacgtgatag taaggcgtat atagcggata agggggcctc
      361 aaactctaaa gtccaaaaag gtagtcgtaa cctatatgcg taaatcacga gagcaactga
      421 atttgtccat tcgaggatgg ataaactatt tttcattggg aaatatgaaa agtatagtca
      481 ccagcataga tgagcgtttg catactcgcc tacgagtgat tatctggaag caatggaaga
      541 agaaatcgag acgattatgg ggattgctta agttaggggt tcctaaatgg atagcagata
      601 aggtatctgg ctggggcgac cactatcaat tatagtaaaa tgaaataaga atagaacaaa
      661 tcgatcagga tagtcaaatc gatttctaac aatgttttag aagcagaggt gaactattct
      721 agtttcaatc cactatagta gctcagaagt cggtacttaa acgtgctata tcaaaaccag
      781 tccttgaaaa acgtggattg gtttcgtgtt tggattatta ccttgaacga catgcgttaa
      841 aaagttagtt gaaccgccgt atgccgaacg gtacgtacgg tggtgtgaga ggggctagag
      901 attatcccct actcgatttt aaatcacatg acgttcaaag gcatcatctg aaatcccttg
      961 ttccaagatg agttttgccc attctttagc agagaagagg ctgtggtcct tgtagtttcc
     1021 gcaagattcg atggttgtcc ctgggacatc ttcccaagta gtagtttcag cgatttcctt
     1081 gagcgaatcc ttgataacag ctgcgatttt agcactggtg tgacgtcccc acataatcat
     1141 gtggaagcct gtgcggcaac caaatggtga acagtcaatc atgccgtcaa tgcgggtacg
     1201 gatgagtttg gctaagaggt gctcgatagt gtgaaggccg gcagtaggga tagagtcttc
     1261 gtttggttgc accaagcgaa tatcataatt ggagatgatg tctccttttg gtcctgtttc
     1321 ttccccaatc aagcgaacat agggtgcttt gacaatggtg tggtcaagtt caaaactttc
     1381 gacaataact tcttttgaca tggtaaatcc tttcagtttt cttctctcat tatatcataa
     1441 aggttgctcc tgagacagag agaaaacctc tccgaggctg gagaggttga aatctttact
     1501 tacgatataa gcggtcgtat tggtagtatg ggtcaaaggt tacgttgata cccagtttac
     1561 gaaggacatt cttgtcttca tcagtcaaga tgatggttga gtgggcttcg cttcctttga
     1621 ggttgccgag ttcttccata gcgcgggcag catcaggatt ttctgtagct gtgatagcaa
     1681 gtgcaatcag gatttcattt gaatgaaggc gtggattgcg gctaccgaga tgatcgattt
     1741 taagaccttg gattggctta acaacttcag gctcgattag ttttacttct ttagcgatgt
     1801 cagctgattt tttgatggcg ttgatcaagg cagcggctgt aggcccaaag agttctgagt
     1861 tcttaccagt gacgatttcc ccatttggca attcaaaggc tagggctggt ccaccagttt
     1921 cttctgcttt ttggcgcgca acgacagcaa ccttacggtc tgcaggtgtg ataccgaggt
     1981 cgttcatgag caactcaatt ttcttgacgg cagcttcgcc aactttttca gctttgaagt
     2041 caagaactgt ttgatagtaa cggcggatga tttcttgttt agaagcttcg acagcagcct
     2101 cgtcatctgt aatagcgaaa ccaaccatgt tgacacccat atctgtcggt gaagcgtatg
     2161 gtgattttcc gagaatacgt tccaacatgc gcttgagcac tgggaagatt tcgatatcac
     2221 ggttgtagtt gacagtggtt tctccatagg tttgaagatg gaaggggtca atcatgttga
     2281 catcatcaag gtcagctgtg gcagcttcat aagccaagtt aactggatga tgaaggggaa
     2341 gattccaaac agggaaggtt tcaaatttag cgtagccaga cttgatgcca ttgatttggt
     2401 cgtggtacat attggacata cacgttgcca attttccaga accgggtcca ggagcggtta
     2461 cgacaatcaa gttgcgactg gttttgatgt agtcgttttt gcccatgcct tctggggaaa
     2521 tgatgtgatc catatccgtc ggatatcctt tgattggata atgaagataa gaatcaattc
     2581 cgtttttctc aagttggttg cggaaggcat ctgcagcgag ttggccagcg tattgtgtaa
     2641 tgacaacgga accaacaaaa atccctaatt cattgaattt gtcaatcaaa cgaagaactt
     2701 cttggtcata agaaatgcct aagtcgccac gtgctttgga atgttcaatg ttgctagcat
     2761 taatggcaat cacaacctca acctgctctt tcaattcttg caagagcttg attttgttgt
     2821 caggttcata accaggaagg acacgagcag cgtggaaatc ttctaacatt ttaccgccaa
     2881 actctaagta gagcttgccg tcaaattggt taatgcgctc taagatgtgg tcgcgttgta
     2941 aattcaaata ctgttcagaa ctaaaagctt gttttttcat ttttttacct ctggattcta
     3001 ttataataaa aaattggaag ttaggaaact acggagctaa aaaagaaatt aaaaagatta
     3061 agcaaacgct tgcacaaaat tttaaaaagt gctatcatat actatagatt attaaaataa
     3121 tgaggtaaac agatgcaaga aaaatggtgg cataatgccg tagtctatca agtctatcca
     3181 aagagtttta tggatagtaa tggagatgga gttggtgatt tgccaggtat taccagtaag
     3241 ttggactatc tagctaagct aggaatcaca gcgatttggc tttctcccgt ttatgacagc
     3301 cctatggatg ataatggcta tgatattgct gattatcaag cgattgcggc tatttttgga
     3361 accatggagg acatggatga actgattgca gaagctaaga agcgtgatat ccgtatcatc
     3421 atggacttgg tggtcaatca tacctcggat gagcatgcct ggtttgtaga ggcctgtgaa
     3481 aatcctaata gccctgagcg agactactat atctggcggg atgagcctaa cgatttagat
     3541 tctatcttta gtgggtctgc ttgggaatac gatgaaaagt caggtcaata ctatctccac
     3601 tttttcagca agaaacagcc ggatctcaac tgggaaaatg aaaaacttcg ccagaaaatt
     3661 tatgagatga tgaacttctg gattgataag ggtattggtg gtttccgtat ggatgttatt
     3721 gacatgattg gcaaaattcc tgacgagaag gtagtcaata atggtcctat gctccatccc
     3781 tatctcaagg aaatgaatca ggcgaccttt ggagataagg atctcttgac agtaggggag
     3841 acttggggag caacgccaga gattgccaaa ctctactctg atccaaaggg gcaagaattg
     3901 tctatggtct tccagtttga acatatcggt cttcagtatc aggaaggtca acctaaatgg
     3961 cactatcaaa aagagctgaa tatcgctaag ttaaaagaaa tcttcaacaa atggcagaca
     4021 gagttaggag ttgaggacgg ctggaattcc ctcttctgga acaaccatga cctccctcgt
     4081 attgtctcaa tctggggaaa tgaccaagaa taccgcgaaa aatctgccaa agcctttgca
     4141 atcttacttc atctcatgag aggaactcct tatatctacc aaggtgagga gattgggatg
     4201 accaactatc cgtttgaaac actggatcaa gtagaagata ttgaatctct caactatgcg
     4261 cgtgaggctc ttgaaaaagg tgttccgatt gaagaaatca tggacagtat ccgtgttatt
     4321 ggacgtgaca atgcccgtac ccctatgcaa tgggacgaga gcaaaaacgc tggtttctca
     4381 acaggtcaac cttggttggc agttaatcca aattacgaga tgatcaacgt ccaagaagcg
     4441 ctggcaaatc cagattctat tttctatacc tatcagaaac tggtccaaat tcgcaaggag
     4501 aatagctggc taattcgagc tgactttgaa ttgcttgata cggctgataa ggtctttgct
     4561 tatatacgta aggatggcga ccgtcgcttc ctagttgtgg ctaacttgtc caatgaagag
     4621 caagacttga cagtagaagg aaaagtcaaa tctgtcttga ttgaaaacac cctagctcaa
     4681 gaagtctttg aaaaacaaat cttagttcca tgggatgctt tctgtgtgga attactataa
     4741 atattttttg cagaaaaatt taaaattgaa atcgtataaa aacaagggag gactgtataa
     4801 aaggcagaaa tcctttgttt tttataacca aggtttataa accttcattc tcgaaattca
     4861 attaacttta caaattccca ctattaagga gaaagaagac gaacataaag aagcgtatcc
     4921 ttagtgcagg cctgactttt acatctgctt tgcttttagc tgcttgcgac caatcaggtt
     4981 cagatacaaa aacttactca tcaaccttta gtggaaatcc aactacattt aactatctat
     5041 tagactatta cgctgataat atagtcaatt gaaacaagaa caagacaaaa gagcctcata
     5101 aaaggtattg caacttggta ataccttttt gaggtgcttt ttgatatgag cccatgtttt
     5161 ctcaatagga ttgtactcag gtgagtaggg aggaagaggt aaaagtttat gcccaaactc
     5221 ttcgcataaa agttctagct tccccattct atggaatctt gcattatcca taataataac
     5281 cgatggtgtg gttaatgttg gtaagaaaaa cttctgaaac catacttcaa aaaagtcgct
     5341 cgtcatcatc tcttcgtaag tcattggagc gattaattca ccatttgtta gacctgcaac
     5401 caaagaaatc ctctgatatc ttcttccaga tactttgcct cttcttaact gaccttttaa
     5461 tgagcgacca tattctcgat aaaaataagt atcgaatcct gtttcatcaa tctaaacagg
     5521 tgctaggtgc tttaaactat taaaattctt aagaaataag gctacttttt ctgggtcttg
     5581 ttcataatta gattgaaact agagtagtag acctctgctt ctaaaacatt gttagaaatc
     5641 gatttgactg tcctgatcga tttgtcatgt tcttatttca ttttactata tttttgtttc
     5701 gcgggaagtc tactaagata cttaaagatg cagatagtaa aaaaaatgtg tcaatcgaaa
     5761 gtgattatgt ccccaaaaaa tggagagttt gagggcaatt attttgattt catttgacac
     5821 gaggaaccct tgaagctgtt ttgttagcta aaccaaggct agtcttagcc ttggctcgcc
     5881 agcctaacag ctccaagcct cttatcaaat gaaatacttg tcttacactc ctcactttc
//
LOCUS       DAVKMJ010000080         5878 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000080 DAVKMJ010000000
VERSION     DAVKMJ010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5878
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.080"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            109..1809
                     /locus_tag="VW348_002056"
     CDS             109..1809
                     /locus_tag="VW348_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEU9746892.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            1802..2278
                     /gene="ilvN"
                     /locus_tag="VW348_002057"
     CDS             1802..2278
                     /gene="ilvN"
                     /locus_tag="VW348_002057"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEU9746893.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            2344..3366
                     /gene="ilvC"
                     /locus_tag="VW348_002058"
     CDS             2344..3366
                     /gene="ilvC"
                     /locus_tag="VW348_002058"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU9746894.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            3473..3709
                     /locus_tag="VW348_002059"
     CDS             3473..3709
                     /locus_tag="VW348_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746895.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMNFEQFFKLAQI
                     SREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            3947..4303
                     /locus_tag="VW348_002060"
     CDS             3947..4303
                     /locus_tag="VW348_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEU9746896.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            4353..5603
                     /gene="ilvA"
                     /locus_tag="VW348_002061"
     CDS             4353..5603
                     /gene="ilvA"
                     /locus_tag="VW348_002061"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEU9746897.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
BASE COUNT         1819 a          994 c         1342 g         1723 t
ORIGIN      
        1 taaacgttaa aatagaaaat tcagaaaatt tcttctttta tcttgaaaaa ttttgaaaaa
       61 atggtatgat agtaacaagt tatttttaag aggaaagaaa ggggaacaat ggagaaaatc
      121 agtttagaat ctcctaagac ggggtcggac ctagttttgg aaacacttcg tgatttagga
      181 gttgatacca tctttggtta tcctggtggt gcggttttgc ctttttatga tgcgatatat
      241 aattttaaag gcattcgcca cattctaggg cgccatgagc aaggttgttt gcatgaagct
      301 gaaggttatg ccaaatcaac tggaaagttg ggtgttgccg tcgtcactag tggaccagga
      361 gcaacaaatg ccattacagg gattgcggat gccatgagcg atagcgttcc ccttttggtc
      421 tttacaggtc aggtggcgcg agcagggatt gggaaggatg cctttcagga ggcagacatc
      481 gtgggaatta ccatgccaat cactaagtac aattaccaag ttcgtgagac agctgatatt
      541 ccgcgtatca ttacggaagc tgtccatatc gcaactacag gccgtccagg gccagttgta
      601 attgacctac caaaagatat atctgcttta gaaacagact tcatttattc accagaagtg
      661 aatttaccaa gttatcagcc gactcttgag ccgaatgata tgcaaatcaa gaaaatcttg
      721 aagcaattgt ccaaggctaa aaagccagtc ttgttagctg gtggtggaat tagttatgct
      781 gaggctgcta cggaactaaa tgaatttgca gaacgctatc aaattccagt ggtaaccagt
      841 cttttgggac aaggaacgat tgcaacgagt cacccactct ttcttggaat gggaggcatg
      901 cacgggtcat tcgcagcaaa tattgccatg acggaagcgg actttatgat tagtattggt
      961 tctcgtttcg atgaccgttt gacggggaat cctaagactt tcgctaagaa tgctaaggtt
     1021 gcccacattg atattgaccc agctgagatt ggcaagatta tcagtgcaga cattcctgta
     1081 gttggagatg ctaagaaggc cttgcaaatg ttgctagcag aaccaacagt tcacaacaac
     1141 actgaaaagt ggattgagaa agtcactaaa gacaagaatc gtgttcgttc ttatgacaag
     1201 aaagagcgtg tggttcaacc gcaagcagtt attgaacgaa ttggtgaatt gacgaatgga
     1261 gatgccattg tggtaacaga cgttggtcaa caccaaatgt ggacagctca gtattatccc
     1321 taccaaaatg aacgtcagtt agtgacttca ggtggtttgg gaacaatggg ctttggaatt
     1381 ccagcagcaa tcggtgctaa aattgctaac ccagataagg aagtagtctt gtttgttggg
     1441 gatggtggtt tccaaatgac caaccaggag ttggctattt tgaatattta caaggtgcca
     1501 atcaaggtgg ttatgctgaa caatcattca cttggaatgg ttcgccagtg gcaggaatcc
     1561 ttctatgaag gcagaacatc agagtcggtc tttgataccc ttcctgattt ccaattgatg
     1621 gcgcaggctt atggtattaa aaactataag tttgataatc ctgagacctt ggctcaagac
     1681 cttgaagtca tcactgagga tgttcctatg ctaattgagg tagatatttc tcgtaaggaa
     1741 caggtgttac caatggtacc ggctggtaag agtaatcatg agatgttggg ggtgcagttc
     1801 catgcgtaga atgttaacag caaaactaca aaatcgttca ggagtcctca atcgctttac
     1861 aggtgtccta tctcgtcgtc aggttaatat tgaaagcatc tctgttggag caacagaaga
     1921 tccgaatgta tcgcgtatca ctattattat tgatgttgct tctcatgatg aagtggagca
     1981 aatcatcaaa cagctcaatc gtcagattga tgtgattcgc attcgagata ttacagacaa
     2041 gcctcatttg gagcgcgagg tgattttggt taagatgtca gcgccagctg agaagagagc
     2101 tgagatttta gcgattattc aacctttccg tgcaacagtg gtagacgtag cgccaagctc
     2161 gattaccatt cagatgacgg gaaatgcaga aaagagcgaa gccctattgc gagtcattcg
     2221 cccatacggt attcgcaata ttgctcgaac gggtgcaact ggatttaccc gcgattaaaa
     2281 atccaactta aatttattaa accagcctaa aaggcaataa ataatagaaa agagagaaaa
     2341 gctatgacag ttcaaatgga atatgaaaaa gatgttaaag tagcagcact tgacggtaaa
     2401 aaaatcgccg ttatcggtta tggttcacaa ggacatgcgc atgctcaaaa cttgcgtgat
     2461 tcaggtcgtg acgttattat cggtgtacgt ccaggtaaat cttttgataa agcaaaagaa
     2521 gatggatttg atacttacac agtagcagaa gctactaagt tggctgatgt tatcatgatc
     2581 ttggcgccag acgaaattca acaagaattg tacgaagcag aaatcgctcc aaacttggaa
     2641 gctggaaacg cagttggatt tgcccatggt ttcaacatcc actttgaatt tatcaaagtt
     2701 cctgcggatg tagatgtctt catgtgtgct cctaaaggac caggacactt ggtacgtcgt
     2761 acttacgaag aaggatttgg tgttccagct ctttatgcag tataccaaga tgcaacagga
     2821 aatgctaaaa acattgctat ggactggtgt aaaggtgttg gagcggctcg tgtaggtctt
     2881 cttgaaacaa cttacaaaga agaaactgaa gaagatttgt ttggtgaaca agctgtactt
     2941 tgtggtggtt tgactgccct tatcgaagca ggtttcgaag tcttgacaga agcaggttac
     3001 gctccagaat tggcttactt tgaagttctt cacgaaatga aattgatcgt tgacttgatc
     3061 tacgaaggtg gattcaagaa aatgcgtcaa tctatttcaa acactgctga atacggtgac
     3121 tatgtatcag gtccacgtgt aatcactgaa caagttaaag aaaatatgaa ggctgtcttg
     3181 gcagacatcc aaaatggtaa atttgcaaat gactttgtaa atgactataa agctggacgt
     3241 ccaaaattga ctgcttaccg tgaacaagca gctaaccttg aaattgaaaa agttggtgca
     3301 gaattgcgta aagcaatgcc attcgttggt aaaaacgacg atgatgcatt caaaatctat
     3361 aactaattag aaatatatag cgctggagat gattttatga aaaagattat gagaaaaact
     3421 gcatcgttat tattggttct agttgtataa tgtaattaca ccgtcggtaa tagtgctagc
     3481 agaccaaaat aaagcagatt ggtcgtatga tgaaaatgct gtaattaaca tttatgatga
     3541 tgctaatttt gaagatggta ggttgcatat gaactttgaa caattcttca aattggcaca
     3601 aatatctaga gaagaaggtc ttgaaattca ttctccgttt gagagagctg gtgcgactaa
     3661 atctgctcgt tatatagcga aatggatttt gagaaataaa aaacattaac aaatatagtt
     3721 ggtaaatcat taggacctaa atcagctgtt agattcggag aagctttatc ctatattgaa
     3781 ggtcctcttc gcagaataaa tgagacgata gatggcggtt tatatcaaat agagcaaatt
     3841 attgcatctg gattgaaaga atcgggttta aatgactgga ctgcgaaaac tttagcttca
     3901 gctattcgtg ggatattaga tgtacttatt taggggttga aatcatatga atattaccaa
     3961 tttgttttct atcaagacag gatgtgatga aactgatagg caactgcaaa aactattttt
     4021 tcagttggat ttacaattgg gagaattgac agatcaacta agaaaattag attctaattt
     4081 tgttcctcgt agtcaatttg tagacacgtt ggatttgaat gatgtagaat ataaagaaat
     4141 tttaaactat tttatcttcc atcgtaatga tagtgaagaa agtttggtag aatggttata
     4201 tgattggatt tccacaaatc gttatgaact tcctaaagag ttttcgattc gtatggctca
     4261 taaataccat gaaagtgtta ctgaagtttt cggagatgaa taactaaaaa acagtcatta
     4321 gtgactgttt tttatagaaa aagaggtttt atatgttaag ttcaaaagat ataatcaagg
     4381 ctcacaaggt cttgaacggt gtggttgtga atactccact ggattacgat cattatttat
     4441 cggagaagta tggtgctaag atttatttga aaaaagaaaa tgcccagcgt gttcgctcct
     4501 ttaaaattcg tggtgcctat tatgccattt cccagctcag caaggaagaa cgtgaacgtg
     4561 gggtagtctg cgcttctgcg ggaaatcatg cgcagggagt agcctatact tgtaatgaaa
     4621 tgaaaattcc tgctactatc tttatgccca ttactacgcc acaacaaaag attggtcagg
     4681 ttcgcttttt tggtggggat tttgtaacta ttaaactagt tggagatacc tttgatgcct
     4741 cagccaaagc agctcaagaa tttacagtct ctgaaaatcg tacctttatt gatccttttg
     4801 atgatgctca tgttcaagca ggtcaaggaa cagttgctta tgagatttta gaagaagctc
     4861 gaaaagaatc gattgatttt gatgctgtct tggttcctgt tggtggtggc ggtctcattg
     4921 ccggggtttc tacctatatc aaggaaacaa gtccagagat tgaggttatc ggagtagagg
     4981 cgaatggagc gcgttccatg aaagctgcct ttgaggctgg aggtccagtc aaactcaagg
     5041 aaattgataa atttgcggat gggattgctg tgcaaaaggt aggtcagttg acctatgaag
     5101 caactcgtca acatattcaa actttggtag gtgtcgatga gggattgatt tctgaaacct
     5161 tgattgacct ttactctaag caagggatag tcgcagaacc tgctggagca gctagtatcg
     5221 cctctttaga ggttttagct gaatatatta aggggaaaac catttgttgt atcatttctg
     5281 gaggaaataa tgatatcaac cgtatgccag aaatggaaga gcgtgccttg atttatgatg
     5341 gtatcaaaca ttactttgtg gtcaatttcc cacaacgtcc aggagctttg cgtgagtttg
     5401 taaatgatat cctggggcca aatgatgata tcacacgttt tgagtatatc aaacgagcta
     5461 gcaagggaac aggcccagta ttaattggga tcgctttagc agataagcat gattatgcag
     5521 gtttgattcg tagaatggaa ggttttgatc cagcttatat taacttaaat ggtaatgaaa
     5581 cgctttataa tatgcttgtc tgaggactaa taaaaaaata tcatattatt tgtacaactg
     5641 atgtatatgt gctataatga agatgaagaa aggggacgat tcctatggtt ttagaaaact
     5701 tatcgtgcaa ttcttacttc tgttcattat agcacttatg atgtttggct cagatttcca
     5761 tccttcattt tgatttccta tctattgaca agcatagtca cactgtcttt aatactcttc
     5821 gaaaatctct tcaaaccacg ttagctctat ctgcaacctc aaaacagtgt tttgagca
//
LOCUS       DAVKMJ010000081         5831 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000081 DAVKMJ010000000
VERSION     DAVKMJ010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5831
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.081"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            43..627
                     /locus_tag="VW348_002062"
     CDS             43..627
                     /locus_tag="VW348_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEU9746898.1"
                     /translation="MSEEINATVSTESTETVDTQGNVDSVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTSAETVSQSVAVLQKSWEQAVQKGVQEKLKGGAPMKQAPV
                     DSDGITKEEFARMGYQSRNELYQKNPELYKKLKG"
     gene            634..1479
                     /locus_tag="VW348_002063"
     CDS             634..1479
                     /locus_tag="VW348_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000123890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N4-gp56 family major capsid protein"
                     /protein_id="HEU9746899.1"
                     /translation="MTAGQTKLATMVNPEVMADMVAAKLPKLIKFTPLAYVETKLEGQ
                     PGSTLTVPAWEYAGDATEIEEGQAITPDQLTTKKTTMTIKKAGKGYEITDESLLSGLG
                     DPLGQATYQLGLAIANKIDNDLVAVAKTATQHITETPTTLEAIDKALDIFEDEEDAQY
                     VAIINPKDATKLKTAVAKEWIKGSELGANMVVSGTFGEVDGVQIVRSKKVDEGKGFLV
                     KVSPSQTQTDDANKYGAFVILLKRDVAIETDRDILKKTTVITGDEHYGVYLYDPTRVV
                     KFGGA"
     gene            1491..1673
                     /locus_tag="VW348_002064"
     CDS             1491..1673
                     /locus_tag="VW348_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HEU9746900.1"
                     /translation="MSLLLRRHYIQEEQVNQYSDLENKTLEELKDLAKEAGVAGAYKL
                     TKAEIVEVLEELKSEI"
     gene            1663..1851
                     /locus_tag="VW348_002065"
     CDS             1663..1851
                     /locus_tag="VW348_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746901.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGEELEITEERYAELADNIASNGVT
                     ISDVLEKILPEPEFLEED"
     gene            1853..2164
                     /locus_tag="VW348_002066"
     CDS             1853..2164
                     /locus_tag="VW348_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEU9746902.1"
                     /translation="MSIELLKKLTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGEHSRTEGGIAVVYGENGLSTGLLQRIRMHRLARVAGHVFEA
                     E"
     gene            2145..2483
                     /locus_tag="VW348_002067"
     CDS             2145..2483
                     /locus_tag="VW348_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746903.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            2458..2973
                     /locus_tag="VW348_002068"
     CDS             2458..2973
                     /locus_tag="VW348_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEU9746904.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNAAIKVVQADAR
                     RLVPVNDGELITSIKTRAKMDGDRAIGEVYTNLKYAPYVEFGTGPKGQASHSGISPEV
                     SVTYKSHPWYVHEDQINVGSYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIQ"
     gene            2970..3338
                     /locus_tag="VW348_002069"
     CDS             2970..3338
                     /locus_tag="VW348_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746905.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDKEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGVVDLDSELVFQFRMEN"
     gene            3344..3757
                     /locus_tag="VW348_002070"
     CDS             3344..3757
                     /locus_tag="VW348_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEU9746906.1"
                     /translation="MLANGITLSYSKTKGSYTKLVGLKEVPEFGIELEKVENTTLEDT
                     VKKYELGIGDVGELEYKFSYNNSSATAPYRVLRKAADDKEKLYFEQAYPDGTKVTFEG
                     QVSVKLGGGGVNAVIDFTLKIALQSELEFADGVGG"
     gene            3762..4142
                     /locus_tag="VW348_002071"
     CDS             3762..4142
                     /locus_tag="VW348_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746907.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSLEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKDKKTSKKKMTVDK"
     gene            4181..4531
                     /locus_tag="VW348_002072"
     CDS             4181..4531
                     /locus_tag="VW348_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746908.1"
                     /translation="MFLDIGGKPLDFWDLTVLEIREMIESYNRVKIQERKEKIIDSYR
                     LSQMISNHVSLLLSKDAKAFEFWEYAPELFVEEQQAVEQERQKQALLLHKERMREFAE
                     RHNRKRKEEVNGNS"
     gene            4518..>5831
                     /locus_tag="VW348_002073"
     CDS             4518..>5831
                     /locus_tag="VW348_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746909.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDQVKNATAKVR
                     EQSSSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIKSTEAFKRFSNGQSWDQLDFQTQQQ
                     IRLMAILEQATAKYGDTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAG
                     DSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKG
                     GGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDA"
BASE COUNT         1880 a         1053 c         1423 g         1475 t
ORIGIN      
        1 aacgagatta tcgagtggcg acgtaatcgc tggaggacaa ttatgtcaga agaaatcaat
       61 gcaactgtat ctactgaatc aactgagact gtcgacactc aaggaaatgt tgattcagtg
      121 caggaagaaa agcacgaacg aactttcact cgtgctgaaa tcggtaagat gctatctgcc
      181 gaacgctcta aatgggaagc tgagcaagaa gccaaggaaa acgaagctaa gaaacttgcc
      241 aagatgaacg ctgacgagaa acaaaaatat cagttggatc agcgtgagca agaactagct
      301 gaccgtgaga aggctattgc tcgcaaggaa ttgaccgcag aagctaaagc aatgctaagt
      361 gaacgtgact tacctgttga gttagtaaat gtagttgatt tgacaagcgc agagacggta
      421 tcgcagtctg tcgctgtatt gcagaaatca tgggagcaag ccgtgcaaaa aggcgttcaa
      481 gaaaaactaa aaggcggagc tccaatgaaa caagcgccag tcgatagtga cggtatcaca
      541 aaagaagaat ttgctcgtat gggttatcag agtcgaaatg agctctatca aaagaaccca
      601 gagctttata agaaattgaa aggataatag aaaatgacag caggacaaac taaattagcc
      661 actatggtta atccagaagt aatggcggat atggtagccg ctaaattacc taaattgatt
      721 aaatttacac cgctagcgta tgtagagaca aagcttgaag gtcaaccagg tagcacttta
      781 acagtgccag catgggagta tgcaggagac gctactgaaa ttgaagaagg ccaagcaatt
      841 acgccagacc aattgactac taaaaagact actatgacca tcaaaaaagc aggtaaaggt
      901 tatgaaatta ccgatgagtc tcttttgtca ggtcttggtg acccactagg tcaagcgact
      961 taccagcttg gtttagctat tgccaacaag atcgataatg atttggtagc ggtagctaaa
     1021 actgcaacac aacatattac agaaactcca acaactcttg aggcaatcga taaagctcta
     1081 gatatctttg aggacgaaga agatgcacag tatgttgcta tcatcaaccc taaagatgct
     1141 actaagctaa aaactgcagt agcaaaagaa tggattaaag gttcagagct tggagcaaat
     1201 atggttgttt ctggaacctt cggtgaagtt gatggtgtgc aaatcgtgcg ctctaaaaaa
     1261 gttgatgaag gtaaaggctt ccttgttaaa gtgtcaccaa gtcaaactca gacagacgac
     1321 gctaacaaat atggagcttt tgttatcttg cttaaacgtg atgtggctat cgaaacagac
     1381 cgcgatatct tgaagaagac taccgtaatc acaggtgatg aacactacgg cgtttacctt
     1441 tacgacccta cacgagttgt aaaattcggt ggcgcgtaag aggtgacgat atgagtttat
     1501 tgctacgacg tcattatatt caagaagagc aggttaacca gtattctgat ttagagaata
     1561 aaactctaga agagttgaag gatctagcga aagaagcagg tgtagcaggc gcttataagt
     1621 tgacaaaagc cgaaattgta gaagttttgg aggaactaaa aagtgaaatt taaaatcaaa
     1681 caagatttct atgattggga atcaaatgtg aaacgactgg caggagagga acttgagatt
     1741 actgaggagc gctatgctga gctggctgac aatattgcca gcaacggtgt cactatctca
     1801 gacgttcttg agaaaatcct ccctgaacct gagttcttag aagaggattg atatgtctat
     1861 agagttgctg aagaaattaa caggcgaaga agatactcag cttctcatgt tgctccaaac
     1921 gagggctaca aatcttatct tgtcagagac taatcgcaca tctttgacac ctgctttaag
     1981 tcttttgata cctgaggttg ctatcgagct ccacaaccgc tcaggagcgg aaggagagca
     2041 ttctagaacc gagggtggta tagcagtagt ctacggagaa aacggcctat ctacgggtct
     2101 tctacagcga atacgcatgc acaggctagc aagggtggca ggtcatgttt ttgaagcaga
     2161 gtagactgaa accctatcca atgcgacggt ttgaaaagac tgtcactgag gaaggtgtcg
     2221 cgaaagaagg gtatgccaag gaagctgaga cagtccgcct tgaattgtgg ccagctagta
     2281 gcaagctaca atctgaattg tatggcgagc gtgtcaatga tattttgaac gcaaatgcca
     2341 acaagtcagc tactatcaaa gtaaaagatg gtgtgtgtat cgatagtcag acggaagtga
     2401 ctcatagggt tatttctaaa aaggtctaca cacatcatca agttttggag ttagagcgtg
     2461 tcagggctac taggggcaga taggcttata gctaaatgta gacggttagc tagtaaaaaa
     2521 actggcgagg atatcgtctt acgtgcggta cacaatgctg ctataaaagt tgtccaagct
     2581 gatgcaagaa gactcgtacc agtgaatgat ggagaactta taactagtat caaaaccaga
     2641 gcaaaaatgg acggagatag ggctataggc gaagtttaca ccaaccttaa atacgctcct
     2701 tacgttgagt ttggaacggg acctaagggt caggctagcc attctggtat ctctccagag
     2761 gtcagcgtga cttacaagtc tcatccttgg tatgtgcatg aagaccaaat caatgtagga
     2821 tcttaccact ttcaaaagat tggggagttt tacaagatgt atggtcaacc tgctcagcct
     2881 tatctttatc cagctttgag agacaatcaa gagcgtgtgt ctaagaatat ttcgaattat
     2941 gtccgtagaa agataagaga acaaatacaa tgatcaatat caagcctgtt atttataaag
     3001 aattgcaaaa ggttgcagat aatgtgaccg atacttatcc tagcgattgg gagactttcc
     3061 cagtcgttat ttttttagaa gaacaaaaca agccaggtga ttggtttgac gacaaggaac
     3121 aaaaatcctc tatccgctat aaggtggata tttttgatga taccagcact agtgagttag
     3181 ctgttaaaat caatcagatt tttgagtctt taggtttgcg aagaaccgac tgccaagacg
     3241 tgccagaccc gtctcatttg agacataagg tcatgcgttt tgaaggtgtc gttgacttag
     3301 attcagagct tgtttttcaa tttagaatgg agaattaaaa tatatgttag caaatggaat
     3361 tacgctttct tatagcaaaa caaaaggtag ctatactaag cttgttggat tgaaagaagt
     3421 gccagagttt ggtattgaac tcgaaaaagt agaaaatact actcttgaag atacggtgaa
     3481 gaagtacgag cttggtattg gggacgtagg agaacttgag tacaagttct cttataataa
     3541 ttcaagcgca actgctcctt accgtgtatt gcgtaaggca gcagacgaca aggaaaaact
     3601 ctacttcgaa caagcttatc cagacggtac taaggtcaca tttgaaggtc aagtatccgt
     3661 aaaacttggc ggtggcggtg tcaatgccgt tatcgatttc acccttaaaa ttgctttaca
     3721 gtcagagttg gaatttgcag atggtgttgg aggttaatta aatggcgtta aaatacacaa
     3781 cttggaaagt tactgacgaa aaagagttga agctacgttt gacatctcat caagctgcaa
     3841 ctgtggaaga aaaaatcggc atgaacttgc tgaagatttt catgcctgaa gcaggcgaag
     3901 agttcacttt gccacctttg aaagttatgt tgttgttagt tcacggcgcc ttgcagcagt
     3961 atgaacatgg gtattctctt gaggatgtct atgatttata cgatgaatac gtggacaatg
     4021 gtggagacca aacaacattc atgacagagg tgttaatgcc actctttgaa gtatcgggtt
     4081 ttactccacg aggaagcaag gacaagaaaa cttccaagaa gaaaatgaca gtagacaagt
     4141 aatcttaacg gtaactcaga ttattgagag gctttatcct atgtttttgg acatcggggg
     4201 caagcctctt gatttttggg atttgacggt acttgaaatc agagaaatga ttgaaagcta
     4261 taaccgtgtc aaaatccaag agcgtaaaga aaagattatt gactcataca gactttcgca
     4321 gatgatatcc aaccacgttt ctttattgtt atccaaagat gccaaggcct ttgagttctg
     4381 ggaatatgcg cctgagttgt ttgtagaaga acaacaagca gtagaacagg aacgacagaa
     4441 acaagcactt ttgttgcata aggaacggat gcgtgaattt gcagagagac acaatcgcaa
     4501 aagaaaggag gaagtgaatg gcaactcttg atgaattgaa ggtcatgatt gacgctgaga
     4561 tagcgccttt caggaagaag atgaaagaag tcgagaatca ggtcaaagga acatctgacc
     4621 aagtgaaaaa tgctactgcc aaagttcgtg aacagtcgag ctcaatcggt agtgcgtttg
     4681 gcaagctggc taagttcgct ggttttgcaa tccttggtaa gaaattactt gatgttggga
     4741 tgtattcaac gcagacggct cttgaagtat cagcgtctat gaaccaaatc aagcgacaga
     4801 tgggcgagag ttcgcaatct ttcttaaaat gggttaacga taacgccaac gctatgaata
     4861 tgggtgtggg tgaggctacc aactacggtg cagtctactc aaacctattt tctggattta
     4921 tcaaagacac caataagcta agtgcttata ctgctaagat gttgcagaca tcggcagttg
     4981 ttgctgaagg ttcagggcgc acgattacag acgttatgga gcggattcgc tcaggtctac
     5041 tagggaacac cgaagcaatt gaggacctag gaatcaacgt caatgtggct atgattaagt
     5101 ccactgaagc ttttaaacgt ttctcaaatg gtcaaagttg ggaccaactc gactttcaaa
     5161 cccagcaaca aatccgtctt atggctatcc tggagcaagc tacagccaag tatggagata
     5221 ccttgtctaa ttctgtaaat ggtcgtatca gtctgtttaa gtcgctaatg aaggacgcag
     5281 cattgaacct tggtaactct atgttaccga ttatcaatgc cattatgcct gtcttgaact
     5341 cttttgctat ggtcttaaag aacgttactg ctaaactcgc tgagtttatc gctttgatgt
     5401 tcaacaagaa agcaacagtg aaagatggtg ttggtggagc agttggagac atgggtaacg
     5461 ccatgaagga tgctgcaggc ggagcaggag accttgctga cgcagtagac gacgctggag
     5521 attcagcagg aggacttgct gacaatcttg gagactccgc caaaaacgct aagaaggccg
     5581 ctaaagagtt gctaggtctt ttgggatttg atgagattaa catcttgcaa aaaccaaaag
     5641 atgacgacgc aggcgggtct ggaggcggtg gcaaaggtgg taaaggaaag ggaggcggtg
     5701 gcggaccttt caaagacatc ttgccagaag tcgagttgac cgacatggac aacaaattca
     5761 agagcatttt tgatggtctt ggagataagc tcaaagggtt gtttgacctc ttcaagaaag
     5821 gttttgatgc a
//
LOCUS       DAVKMJ010000082         5697 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000082 DAVKMJ010000000
VERSION     DAVKMJ010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5697
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.082"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            105..584
                     /locus_tag="VW348_002074"
     CDS             105..584
                     /locus_tag="VW348_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEU9746910.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGELSHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            678..749
                     /locus_tag="VW348_002075"
     tRNA            678..749
                     /locus_tag="VW348_002075"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:711..713,aa:Glu,seq:ttc)
     gene            1001..2546
                     /locus_tag="VW348_002076"
     rRNA            1001..2546
                     /locus_tag="VW348_002076"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            2598..2670
                     /locus_tag="VW348_002077"
     tRNA            2598..2670
                     /locus_tag="VW348_002077"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2631..2633,aa:Ala,seq:tgc)
     gene            2795..5696
                     /locus_tag="VW348_002078"
     rRNA            2795..5696
                     /locus_tag="VW348_002078"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1673 a         1107 c         1631 g         1286 t
ORIGIN      
        1 gcctctcttt tttgtgcagt ttaggagcta aagggaacag aatggagaaa atggaacaaa
       61 tgtgttttct aatctgttag actgtatcta gaaaggggaa aattatgatt aaagaattgt
      121 atgaagaagt ccaagggact gtgtataagt gtagaaatga atattacctt catttatggg
      181 aattatcgga ttgggaccaa gaaggcatgc tctgcttaca tgaattgatt agtagagaag
      241 aaggactggt agacgatatt ccacgtttaa ggaaatattt caaaaccaag tttcgaaatc
      301 gaattttaga ctatatccgt aagcaggaaa gtcagaagcg tagatacgat aaagaaccct
      361 atgaagaagt gggtgagctc agtcatcgta taagtgaggg gggtctctgg ctagatgatt
      421 attatctctt tcatgaaaca ctaagagatt atagaaacaa acaaagtaaa gagaaacaag
      481 aagaactaga acgtgtctta agcaatgaac gatttcgagg gcgtcaaaga gtattaagag
      541 acttacgcat tgtgtttaag gagtttacta tccgtaccca ctaggaagtc atgcaaaaaa
      601 aatgaaaaaa attagaaaaa gtagttgaca aagtttgaaa agactgtata atagtaagag
      661 ttgaaaataa caactcaggt ccgttggtca aggggttaag acaccgcctt ttcacggcgg
      721 taacacgggt tcgaatcccg tacggactat ggtatgttgc ggttggaaca cttgatgaaa
      781 aaaagtttaa aaaaacttaa aaatcttcaa aaaagtgttg acaagcgaaa gcagttgtga
      841 tatactaata tagttgtcgc ttgagagaag caagtgacaa agacctttga aaactgaaca
      901 agacgaacca atgtgcaggg cgctacaaca taagttgtag tactgaacaa tgaaaaaaca
      961 ataaatctgt cagtgacaga aatgagtgag aactcaaact tttaatgaga gtttgatcct
     1021 ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct gaaggaggag
     1081 cttgcttctc tggatgagtt gcgaacgggt gagtaacgcg taggtaacct gcctggtagc
     1141 gggggataac tattggaaac gatagctaat accgcataag agtagatgtt gcatgacatt
     1201 tgcttaaaag gtgcacttgc atcactacca gatggacctg cgttgtatta gctagttggt
     1261 ggggtaaggg ctcaccaagg cgacgataca tagccgacct gagagggtga tcggccacac
     1321 tgggactgag acacggccca gactcctacg ggaggcagca gtagggaatc ttcggcaatg
     1381 gacggaagtc tgaccgagca acgccgcgtg agtgaagaag gttttcggat cgtaaagctc
     1441 tgttgtaaga gaagaacgag tgtgagagtg gaaagttcac actgtgacgg tatcttacca
     1501 gaaagggacg gctaactacg tgccagcagc cgcggtaata cgtaggtccc gagcgttgtc
     1561 cggatttatt gggcgtaaag cgagcgcagg cggttagata agtctgaagt taaaggctgt
     1621 ggcttaacca tagtaggctt tggaaactgt ttaacttgag tgcaagaggg gagagtggaa
     1681 ttccatgtgt agcggtgaaa tgcgtagata tatggaggaa caccggtggc gaaagcggct
     1741 ctctggcttg taactgacgc tgaggctcga aagcgtgggg agcaaacagg attagatacc
     1801 ctggtagtcc acgctgtaaa cgatgagtgc taggtgttag accctttccg gggtttagtg
     1861 ccgtagctaa cgcattaagc actccgcctg gggagtacga ccgcaaggtt gaaactcaaa
     1921 ggaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa
     1981 gaaccttacc aggtcttgac atccctctga ccgctctaga gatagagttt tccttcggga
     2041 cagaggtgac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt
     2101 cccgcaacga gcgcaacccc tattgttagt tgccatcatt tagttgggca ctctagcgag
     2161 actgccggta ataaaccgga ggaaggtggg gatgacgtca aatcatcatg ccccttatga
     2221 cctgggctac acacgtgcta caatggctgg tacaacgagt cgcaagccgg tgacggcaag
     2281 ctaatctctt aaagccagtc tcagttcgga ttgtaggctg caactcgcct acatgaagtc
     2341 ggaatcgcta gtaatcgcgg atcagcacgc cgcggtgaat acgttcccgg gccttgtaca
     2401 caccgcccgt cacaccacga gagtttgtaa cacccgaagt cggtgaggta accgtaagga
     2461 gccagccgcc taaggtggga tagatgattg gggtgaagtc gtaacaaggt agccgtatcg
     2521 gaaggtgcgg ctggatcacc tcctttctaa ggataaggaa ctgcgcattg gtcttgttta
     2581 gtcttgagag gtcttgtggg gccttagctc agctgggaga gcgcctgctt tgcacgcagg
     2641 aggtcagcgg ttcgatcccg ctaggctcca ttggtgagag atcaccaagt aatgcacatt
     2701 gaaaattgaa tatctatatc aaatagtaac aagaaaataa accgaaaacg ctgtagtatt
     2761 aataagagtt tatgactgaa aggtcagaaa ataaggttaa gttaataagg gcgcacggtg
     2821 gatgccttgg cactaggagc cgacgaagga cgtgacaaac gacgatatgc cttgggtagc
     2881 tgtaagtaag cgatgatcca gggatttccg aatgggggaa cccaacaggt agtacctgtt
     2941 acccacatct gttaaggatg tgaggaggaa gacgcagtga actgaaacat ctaagtagct
     3001 gcaggaagag aaagcaaaag cgattgcctt agtagcggcg agcgaaacgg cagaagggca
     3061 aaccgaagag tttactcttc ggggttgtag gactgcaatg tggactcaaa gattatagaa
     3121 gaatgatttg ggaagatcag ccaaagagag taatagcctc gtatttaaaa tagtctttgt
     3181 acctagcagt atcctgagta cggcgggaca cgtgaaatcc cgtcggaatc tgggaggacc
     3241 atctcccaac cctaaatact ccctagtgac cgatagtgaa ccagtaccgt gagggaaagg
     3301 tgaaaagcac cccgggaggg gagtgaaata gaacctgaaa ccgtgtgcct acaacaagtt
     3361 cgagcccgtt aatgggtgag agcgtgcctt ttgtagaatg aaccggcgag ttacgttatg
     3421 atgcgaggtt aagttgaaga gacggagccg tagggaaacc gagtctgaat agggcgcctt
     3481 agtatcatga cgtagacccg aaaccatgtg acctacccat gagcaggttg aaggtgcggt
     3541 aagacgcact ggaggaccga accagggcac gttgaaaagt gcttggatga cttgtgggta
     3601 gcggagaaat tccaaacgaa cttggagata gctggttctc tccgaaatag ctttagggct
     3661 agcgtcgaca ttagagattc ttggaggtag agcactgttt gggtgagggg tccatcccgg
     3721 attaccaatc tcagataaac tccgaatgcc aatgaattat ggtcggcagt cagactgcga
     3781 gtgctaagat ccgtagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
     3841 attgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttag cttagaagca
     3901 gctattcatt caaagagtgc gtaatagctc actagtcgag tgaccctgcg ccgaaaatgt
     3961 accggggcta aaacaattta ccgaagctgt ggataccttt ataggtatgg taggagagcg
     4021 ttctatgtgt gatgaaggta taccgtgagg agtgctggaa cgcatagaag tgagaatgcc
     4081 ggtatgagta gcgaaagaca ggtgagaatc ctgtccaccg taagactaag gtttccaggg
     4141 gaaggctcgt ccgccctggg ttagtcggga cctaaggaga gaccgaaagg tgtatccgat
     4201 ggacaacagg ttgatattcc tgtactagag tatgtagtga tggagggacg cagtaggcta
     4261 actaaagcag acgattggaa gagtctgtct aagcagtgag gtgtgaattg agtcaaatgc
     4321 ttaattctat aacattgagc tgtgatgggg agcgaagttt agtagcgaag ttagtgacgt
     4381 cacactgcca agaaaagctt ctagcgttta aacatactct acccgtaccg caaaccgaca
     4441 caggtagtcg aggcgagtag cctcaggtga gcgagagaac tctcgttaag gaactcggca
     4501 aaatgacccc gtaacttcgg gagaaggggt gctgacttta agtcagccgc agtgaatagg
     4561 cccaagcaac tgtttatcaa aaacacagct ctctgctaaa tcgtaagatg atgtataggg
     4621 ggtgacgcct gcccggtgct ggaaggttaa gaggagtgct tagcgtaagc gaaggtatga
     4681 attgaagccc cagtaaacgg cggccgtaac tataacggtc ctaaggtagc gaaattcctt
     4741 gtcgggtaag ttccgacccg cacgaaaggc gtaatgattt gggcactgtc tcaacgagag
     4801 actcggtgaa attttagtac ctgtgaagat gcaggttacc cgcgacagga cggaaagacc
     4861 ccatggagct ttactgcagt ttgatattga gtgtctgtac cacatgtaca ggataggtag
     4921 gagtctaaga gatcgggacg ccagtttcga aggagacgct gttgggatac tacccttgtg
     4981 ttatggccac tctaacccag ataggtgatc cctatcggag acagtgtctg acgggcagtt
     5041 tgactggggc ggtcgcctcc taaaaggtaa cggaggcgcc caaaggttcc ctcagaatgg
     5101 ttggaaatca ttcgcagagt gtaaaggtat aagggagctt gactgcgaga gctacaactc
     5161 gagcagggac gaaagtcggg cttagtgatc cggtggttcc gtatggaagg gccatcgctc
     5221 aacggataaa agctaccctg gggataacag gcttatctcc cccaagagtt cacatcgacg
     5281 gggaggtttg gcacctcgat gtcggctcgt cgcatcctgg ggctgtagtc ggtcccaagg
     5341 gttgggctgt tcgcccatta aagcggcacg cgagctgggt tcagaacgtc gtgagacagt
     5401 tcggtcccta tccgtcgcgg gcgtaggaaa tttgagagga tctgctccta gtacgagagg
     5461 accagagtgg acttaccgct ggtgtaccag ttgtcttgcc aaaggcatcg ctgggtagct
     5521 atgtagggaa gggataaacg ctgaaagcat ctaagtgtga aacccacctc aagatgagat
     5581 ttcccatgat tatatatcag taagagccct gagagatgat caggtagata ggttagaagt
     5641 ggaagtgtgg cgacacatgt agcggactaa tactaatagc tcgaggactt atccaaa
//
LOCUS       DAVKMJ010000083         4384 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000083 DAVKMJ010000000
VERSION     DAVKMJ010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4384
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.083"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..1507
                     /gene="lanM"
                     /locus_tag="VW348_002079"
     CDS             <1..1507
                     /gene="lanM"
                     /locus_tag="VW348_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type 2 lantipeptide synthetase LanM"
                     /protein_id="HEU9746911.1"
                     /translation="GNIFSSLVFYLEDLIYPWIVKPLVLEINSLREKGLLEGESEQQR
                     YKYFITLFDKEENILNFYNKYPVLLRQISESCLRFYTYFIEILSNLENDFSVLEEELG
                     LRGKLNDIKFGKGDTHSQGKTVLILFFDDAKIVYKPKNLIINNSLNTIAEYIRKVDEK
                     IRIRIPRTIAYSDHSYEEFIDYLPLEQKKNLPEYYYNFGVLLAFIYLFNGSDIHFENL
                     ISYGDMPVIIDFETMLQQPLFDDKTGQSLLDTLFHRVTRTLLLPTEGVKREDGLDVEM
                     SALTGNFKKDAFNGQVLINLNTDKVKFDIGKIDFEGGKNLPVRDGDIEFDKYIKDFKK
                     GFRDFYLIFEELNKTEEFKMLLKANLYGLKTRVLFRDTNSYASVLSFLYHPDFYEEML
                     DREKALENLWSNKFSNQGIVASECEQMRLLDIPIFYTDTNINEIYDDFGNHFISLHQF
                     SGYDYFMKYLPNNNLENLEKQLDIIEIYFPSFDQRKKGYKLNLSNRKKTPK"
     gene            1557..2567
                     /locus_tag="VW348_002080"
     CDS             1557..2567
                     /locus_tag="VW348_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001834714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin formation protein"
                     /protein_id="HEU9746912.1"
                     /translation="MVINNIYDEYPIWSIPVNFKGSKWCLEQTGNDMYRGRAGILLFM
                     YYVKLLKDKSSYTQLYNKMLSAIPPSVSLSKTTFGLTGDIGYFIVLSIIEDYDTNTLA
                     CLNYIKSVLTELEKTDFASVSNKSDYINGLLPLINTLVRYYRRGIEKERVLRLVLSLG
                     DTLYNDVSERDNSNFGYSFGHGLSGVIFTLKNIYKVTRLKKYKELILQLVPREKIKIH
                     SLKWCSGEFGTLVNHPQSVPEGIVASLDNDTFCHGSMAIINFYIDYMKEMDTSMELES
                     LLCSVVMNKSKEGEYRIVQTSNFPDFSLYTGVTGIAYTFLRYIALNQNDKKIVIPSLL
                     EI"
     gene            2917..3621
                     /locus_tag="VW348_002081"
     CDS             2917..3621
                     /locus_tag="VW348_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HEU9746913.1"
                     /translation="MNKIFIYAGVRNHNSKTLEYTKRLSSIISSRNNVDISFRTPFNS
                     ELEISNSDSEELFKKGIDRQSNADDGGVIKKELLESDIIIISSPVYLQNVSVDTKNFI
                     ERIGGWSHLFRLAGKFVVTLDVAESNGSDNVSEYLRDIFSYMGGQILHQVSITNSLKD
                     IAEAQLMEATYKIEDVLEGKIKYKTTDYQERAYQTLKLILENYDSEHFEKMYWEKKRL
                     FEANSLEEWYYVENIK"
     gene            3602..>4384
                     /locus_tag="VW348_002082"
     CDS             3602..>4384
                     /locus_tag="VW348_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HEU9746914.1"
                     /translation="MLKILNNSVIYLCLIPLLFLLLIIFPNDSLIYYFRLILISLISI
                     TLHELGHFLVGRCLSYKLEMLATPFFFYFRKKIYFKFPVLLAFGYCQMSNRNITNEKN
                     SDRNLVFYFFGGGGANLIVAILALLGFVPYASEFFILNIILFLVTVCLPIDGTDGNAI
                     REIVLYSKDSKTYQRFFANSLYNNPYITIDDFAKLTSKEKSFFSKFEKCLINLYFEVK
                     GEGSAFTIANHEVFDSNIQENIIHEYYKLLHKSSDWIIPQNLS"
BASE COUNT         1566 a          520 c          766 g         1532 t
ORIGIN      
        1 tggaaatatt ttttcctctc tagtatttta tttagaagat ttaatctatc cttggattgt
       61 taaacctttg gttttagaga taaattcatt gcgtgaaaaa ggtttacttg aaggggaatc
      121 ggagcagcaa cggtacaaat attttataac attgtttgac aaggaagaga atatattaaa
      181 tttttataac aaatatcccg ttttactgag gcaaatatcg gagtcttgtc ttcggttcta
      241 tacttatttt atagaaattt tatcaaattt agaaaatgat tttagtgtgc tagaagaaga
      301 attagggcta agggggaaat taaatgatat aaaatttgga aagggtgata cacacagcca
      361 aggaaaaact gttttgatac tcttctttga tgacgcgaaa attgtttaca agcctaaaaa
      421 tttaataatc aataactcac taaatactat tgctgagtat atccgaaagg ttgatgaaaa
      481 aattaggata agaatacctc gaactattgc ttattcggat cacagctatg aagaatttat
      541 tgattatcta cctctagagc aaaagaaaaa tttacctgaa tattattata attttggtgt
      601 gcttttagca tttatatatt tatttaatgg gagtgatata cattttgaaa atttaatttc
      661 ctatggagat atgcctgtaa taatagactt tgaaacaatg ttacagcaac ctctatttga
      721 tgataaaact ggtcagagtt tgctggatac cctgtttcac agggtgactc gaactttgct
      781 tcttccaaca gagggagtaa aaagggagga tggtcttgat gttgagatga gtgctcttac
      841 aggaaatttt aagaaggatg cttttaatgg tcaagtttta attaatttaa atactgataa
      901 ggtaaagttt gatattggga aaattgattt tgaaggtggg aaaaacctgc ctgttcggga
      961 tggtgatata gaatttgata agtatataaa agatttcaaa aaaggtttta gggattttta
     1021 tctgatattt gaagagttaa ataaaacaga agaatttaaa atgctattaa aagcaaactt
     1081 gtatggttta aagacaaggg tactttttag agacacaaat agctatgctt cagtactatc
     1141 ttttttatat catcctgatt tttatgaaga aatgttagat agagaaaaag cattggaaaa
     1201 tctctggagc aataagtttt ctaatcaagg tattgtagca agcgaatgtg aacaaatgag
     1261 gttattagat attccgattt tttatacaga tacaaatatc aatgaaatct acgatgattt
     1321 tggaaatcat tttatttccc tacatcaatt ttctggatat gactatttta tgaaatattt
     1381 acctaataat aatttggaaa atttagaaaa gcaacttgat atcattgaaa tttattttcc
     1441 aagctttgat cagcgaaaaa aaggatataa attaaactta tctaatagaa aaaaaactcc
     1501 caaatgaaag tttagttact attctgcata atgaagtaga aaatattgca gactctttgg
     1561 ttattaataa tatttatgac gaatatccaa tttggagtat acctgttaat tttaaaggtt
     1621 ctaaatggtg tcttgaacaa acgggtaatg atatgtatag gggtagagct ggaatattac
     1681 tgtttatgta ctatgtaaaa ttattgaaag ataaatcatc atatactcaa ctgtacaata
     1741 aaatgttatc tgcaattccg ccatctgttt ctttatctaa gaccacattt ggtttaactg
     1801 gggatatagg atatttcatt gttctatcca ttatagagga ttacgataca aatactctcg
     1861 catgcttaaa ttatataaag agtgttttaa ctgagcttga aaagactgat tttgcaagtg
     1921 tttcaaacaa gtctgactat attaatggtc ttctaccttt aattaataca ctggtaagat
     1981 attataggag aggaatagag aaggaacgtg ttctaaggct agtattaagt ttaggtgata
     2041 cgctatataa tgatgtaagc gagagagata atagtaattt tggatatagt tttggccatg
     2101 gactatcagg tgtaattttt acattaaaaa atatttataa agtgacaaga cttaaaaaat
     2161 ataaagaatt aattttacaa ctagttccta gggagaaaat caaaattcat tctttgaagt
     2221 ggtgtagtgg agaatttggg acattagtta atcatcccca aagtgttcca gagggaattg
     2281 tagctagttt agataatgat acattttgcc atggaagtat ggccataata aatttttaca
     2341 tcgactacat gaaagaaatg gatactagta tggaattgga gtctttattg tgtagtgttg
     2401 taatgaataa atcaaaagaa ggagagtatc gtatcgtcca aacaagcaat ttcccagatt
     2461 tttctttgta tacaggtgtg actggtattg cttatacttt tttaaggtat atcgcactga
     2521 atcagaatga caaaaagata gttatcccct cattacttga aatctagctt aatttatagt
     2581 tttgtttcta aaatagaggt gtccactcat taagcaatat aaaaatacca agattgacta
     2641 gtttaatatg taattctata aaatattttt aatagtgtag cttttcattg agataataat
     2701 ataataaaga aaagttctat tctaattgct aaacggcttg aggtatatgc tactgttata
     2761 gaaatgattt taaactaaaa tcaaaattac tccaaaaata gtattgattt tggtttaata
     2821 caaaacatat gtaataatgt gagtcaacaa aagtctgttt ttgtaccata ctatcttgaa
     2881 aaatctacta aattcaaatt gagaggatga attaaaatga ataaaatatt tatatatgca
     2941 ggagtgcgaa atcataactc taagacttta gagtatacta agagactttc aagtatcatt
     3001 tctagtagaa ataatgttga tatatctttc aggacacctt tcaattcaga gctagaaata
     3061 tctaattctg attcagaaga gttgtttaag aaaggaattg ataggcaaag taatgctgat
     3121 gatggaggtg ttataaaaaa agagttatta gagtctgata ttataattat ctcttctcct
     3181 gtatatttac aaaacgtatc tgtggacaca aaaaacttta ttgaaaggat tggggggtgg
     3241 agccatcttt ttcgattagc tggaaagttt gttgtaacat tagatgttgc tgagagtaac
     3301 ggctctgata atgtgtcaga atatcttaga gatatatttt catatatggg aggacagata
     3361 ttacaccaag tttcaattac caattcactc aaagatattg cagaggctca gttgatggag
     3421 gcaacttata aaattgaaga tgtacttgaa gggaaaatta agtacaaaac aacggattat
     3481 caagaaagag cttaccagac attaaaatta attttagaaa attatgattc cgaacatttt
     3541 gagaagatgt attgggagaa aaaacgcctt tttgaagcta atagtttaga ggaatggtat
     3601 tatgttgaaa atattaaata actctgtcat atatttatgt ttgattccgt tattgttcct
     3661 attattgata atttttccaa atgattcatt aatctattat tttcgattga ttttaatttc
     3721 gttaatatca attacattac atgaactagg tcatttttta gtgggaagat gtttatctta
     3781 taaactagag atgcttgcta ctcccttttt cttctatttc agaaaaaaaa tatatttcaa
     3841 atttccagtg ttattagcat tcggttattg tcaaatgagt aatagaaaca ttactaatga
     3901 aaaaaatagt gataggaatt tggtgttcta cttctttggg ggaggtggag ctaacctaat
     3961 tgtcgcaata ttagcacttt tgggatttgt gccgtacgca tcagaatttt ttattttgaa
     4021 tataattctt tttctagtta cggtatgttt accaattgat ggaacagatg gcaatgctat
     4081 tagagagata gttttgtatt caaaagattc aaaaacatat cagagattct ttgcgaacag
     4141 tctctataat aatccttata taacaatcga cgattttgca aaattaacct ctaaagaaaa
     4201 atcttttttt tcaaaatttg aaaaatgttt gataaacctt tactttgaag tgaaaggtga
     4261 agggtcagca tttacaattg ctaatcatga agtttttgat tcaaatattc aggaaaatat
     4321 tatccatgag tactataaat tactacataa atcttctgat tggattattc cacagaactt
     4381 atct
//
LOCUS       DAVKMJ010000084         4121 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000084 DAVKMJ010000000
VERSION     DAVKMJ010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4121
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.084"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(148..1209)
                     /gene="dinB"
                     /locus_tag="VW348_002083"
     CDS             complement(148..1209)
                     /gene="dinB"
                     /locus_tag="VW348_002083"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEU9746915.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITLTGF"
     gene            1558..3882
                     /gene="pflB"
                     /locus_tag="VW348_002084"
     CDS             1558..3882
                     /gene="pflB"
                     /locus_tag="VW348_002084"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEU9746916.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            complement(3924..>4121)
                     /locus_tag="VW348_002085"
     CDS             complement(3924..>4121)
                     /locus_tag="VW348_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9746917.1"
                     /translation="LKNKEKIVNALQLPYSNAKLEATNNLIKLIKRNAFGFRNFENFK
                     KRIFIALNIKKERTNFVLSRA"
BASE COUNT         1233 a          859 c          804 g         1225 t
ORIGIN      
        1 agaaaaacct tgaaggggca actcttcaag gttttatact cttagaaaat ctcttcaaac
       61 cgcgtcagct ttatctgcaa cctcaaaaca gtgttttgag cagcctgcgg ctagcttcct
      121 agtttgctct ttgattttca ttgagcttta aaatccagtc agggtaatcc ccaataggcg
      181 gacacctctt tctttctcgc ttaattcttc atagagttgc agggctattt ggcttatctg
      241 actagcatct tgtgtttttt gagcaagact ttttcgtttg gtaagagttg aaaagtcctc
      301 gtagcggatt ttcaaaatga caatttttcc agctttttct tgttgatgta gattgagagc
      361 gactttttct gatagaagag tcagctcttt tttgatatct tcctcagcaa ggagaatctt
      421 cccgtaggtt ttctccttgc cgattgattt acggatgcga ttggatttga ctggagagtt
      481 gtgaatgcca cgagcctttc gatacagatc atagcctagt ctaccaaaac ggtctattag
      541 ggttacctca ggaacttcaa gtaaatcagc accagtaaaa acgcccattt gatgaagacg
      601 ttctactgtc ttttttccta ctccatgaaa tttggaaata tccatttgtt tgagaaaatc
      661 ctcagcctgt tcaggtagaa tcactgtcaa accatgtggt ttttgataat cactcgccat
      721 tttagctaag aatttgttgt aagaaacgcc tgcggaagca gttagatgga gttcttgcca
      781 gatatctttt tgaatgaggc gagcaatttt gaccgctgac ttgataccga gtttattttc
      841 tgtcacatcc aaataggctt cgtcaatgct catgggttca atcaaatctg tatagcgctt
      901 aaaaatagct cgaatctgga gtcccacaga cttgtatttc tcataattcc ctgagataaa
      961 gacagcctgg ggacaacgtt cataagcttc cttggaactc atggcagaat ggacaccaaa
     1021 agctcttgcc tcataactac aggtagaaac gactccccgt ccacctgttt gccgagggtc
     1081 gcttccaata atgacaggtt ttcctctgag tttaggatta tccctgattt ccactgcagc
     1141 aaaaaaggca tccatgtcaa tatggatgat ttttcttgac aaatcattta acaaaggaaa
     1201 aatcaacatg cctagcacct ttttatactc ttcgaaaatc tcttcaaacc acgtcagctc
     1261 tatctgcaac ctcaaaacag tgttttgagc aatctgcggc tagcttccta gtttgctttt
     1321 cgatttccat tgagtgttac tgcttatttt cttttattat accctttttt ctgaaaaaaa
     1381 gaaaaaagga ctttattttt tcaaaaatat aatacagttt gaaataaaat atagactgtt
     1441 ttagaaaaga aagtgtaaaa atagggaatt ttcacttgtt gaaatcggtt actatatggt
     1501 atacttgtct tatgaatgta acagatgact gttactagaa aaaaagagga cattaatatg
     1561 gttgttaaga cagttgttga agcacaagat atttttgaca aagcttggga aggcttcaaa
     1621 ggcgtagatt ggaaagaaaa agcaagtgta tcacgatttg tacaagctaa ctacacacct
     1681 tatgatggag acgaaagctt ccttgcagga ccaacagagc gttcacttca catcaagaaa
     1741 attgtagaag aaactaaagc acactacgaa gaaactcgtt tcccaatgga cactcgtcca
     1801 acatctatcg ctgatatccc tgctggattt atcgacaaag aaaatgaagt tatctttggt
     1861 atccaaaatg atgaactctt caaattgaac ttcatgccaa aaggtggtat ccgtatggct
     1921 gaaactactt taaaagaaaa tggatacgaa ccagacccag ctgttcacga aatcttcact
     1981 aaatatgtaa caacagttaa cgacggtatt ttccgtgcct acacttcaaa tattcgtcgc
     2041 gctcgtcatg cacacactgt aactggtctt ccagatgcat actcacgcgg acgtatcatc
     2101 ggtgtttacg cacgtcttgc tctttacggt gcagactact tgatgcaaga aaaagtaaac
     2161 gactggaatg caatcaaaga aatcgatgaa gaaacaatcc gtcttcgtga agaagtaaac
     2221 cttcaatacc aagcattgca acaagttgtt cgcctgggtg acctttacgg ggttgatgtt
     2281 cgcaaaccag cgatgaacgt gaaagaagca atccaatggg ttaacattgc tttcatggct
     2341 gtctgccgtg tgattaacgg tgctgctaca tctctaggtc gtgtaccaat cgtattggac
     2401 atctttgcag aacgtgacct tgctcgtggt acatttactg aatcagaaat ccaagaattc
     2461 gttgatgatt tcgttatgaa acttcgtaca gttaaatttg ctcgtacaaa agcttatgac
     2521 caattgtact caggtgaccc aacctttatc acaacttcta tggctggtat gggtaacgac
     2581 ggtcgtcacc gtgttactaa gatggactac cgtttcttga acacacttga caacatcggt
     2641 aactcaccag aaccaaactt gacagttctt tggactgaca aattgccata caacttccgt
     2701 cgctactgta tgcacatgag ccacaaacac tcttctatcc aatacgaagg tgtaacaaca
     2761 atggctaaag acggatatgg tgaaatgagc tgtatctcat gctgtgtgtc tccacttgat
     2821 ccagaaaatg aagaacaacg ccacaacatc cagtacttcg gtgctcgtgt aaacgttctt
     2881 aaagcccttc ttactggttt gaatggtggt tacgacgatg ttcacaaaga ctacaaagta
     2941 tttgatatcg aaccaatccg tgacgaagtt cttgaattcg aatcagttaa agcgaacttt
     3001 gaaaaatctc ttgactggtt gactgacact tacgtagatg ccttgaacat catccactac
     3061 atgactgata gatacaacta cgaagctgtt caaatggcct tcttgccaac taaacaacgt
     3121 gccaacatgg gattcggtat ctgtggattt gctaacactg ttgatacatt gtcagctatc
     3181 aaatacgcta cagttaaacc aatccgtgac gaagatggct acatctacga ttacgaaaca
     3241 atcggtgact acccacgctg gggtgaagat gacccacgtt caaacgaatt ggcagaatgg
     3301 ttgatcgaag cttacacaac tcgtctacgt agccacaaac tatacaaaga cgcagaagct
     3361 acagtatcac ttttgacaat cacatctaac gttgcttact ctaaacaaac tggtaactca
     3421 ccagttcaca aaggtgtata cctcaacgaa gatggttctg tgaacttgtc taaacttgaa
     3481 ttcttctcac caggtgctaa cccatctaac aaagctaaag gtggttggtt gcaaaacttg
     3541 aactcacttt ctagccttga ctttagttat gcagctgacg gtatctcatt gactacacaa
     3601 gtatcacctc gcgctcttgg taagactcgt gatgaacaag ttgataactt ggtaacaatc
     3661 cttgatggtt acttcgaaaa cggtggacaa cacgttaact tgaacgttat ggacttgaac
     3721 gatgtttacg aaaaaatcat gtcaggcgaa gacgttatcg tacgtatctc tggatactgt
     3781 gtaaacacta aatacctcac tccagaacaa aaaactgaat tgacacaacg tgtcttccac
     3841 gaagttcttt caatggatga cgccttggat gcattgagct aatcaagttc ggctctttgt
     3901 caactgcagt gggttgaagt cggctaagct cgagaaagga caaaattcgt cctttctttt
     3961 ttgatgttca gagcgataaa aatccttttt ttgaagtttt caaagttccg aaaaccaaag
     4021 gcgtttcgtt tgataagttt gatgagatta ttggtcgctt ccaattttgc gttggaataa
     4081 ggtaattgaa gagcgttgac gattttttct ttgttcttta g
//
LOCUS       DAVKMJ010000085         4003 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000085 DAVKMJ010000000
VERSION     DAVKMJ010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4003
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.085"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..1322)
                     /locus_tag="VW348_002086"
     CDS             complement(<1..1322)
                     /locus_tag="VW348_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEU9746918.1"
                     /translation="MDALTRRQFDRAMFAKERTLAIRVGEYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINADSYFLHGL
                     TKSEIEYQIAGITCKTDKKSLTVGMTTGRSLELDNVFITQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFIFKGGLRGRISADSKAGNDTQYS
                     YEGTITKQIKQQDGFEAKIQAQIEAADKDFDQKVDKIKKDFNDQVELAKARAEEVKRE
                     LSDTINQRFNSFDNGPLKEAKRKAEEALRNAGASSSLAQESKRIGLDSV"
     gene            complement(1327..1677)
                     /locus_tag="VW348_002087"
     CDS             complement(1327..1677)
                     /locus_tag="VW348_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746919.1"
                     /translation="MAQLTINGVAVKPPKSFQVGIQDIDGETGRNANGDMVRDRITTK
                     RKLDCEWGMMTQGEISQLLHAVSSKFFEVSYPDPMDGQVTKTFYVGDRTAPSYTFTEK
                     LKPWSGAKFNLVER"
     gene            complement(1686..3773)
                     /locus_tag="VW348_002088"
     CDS             complement(1686..3773)
                     /locus_tag="VW348_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746920.1"
                     /translation="MFDNIGNIAEAVGNIAQDFSSAFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKDFEKVVVTNAPKISSIFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVAPAINSIANAFNGLIDIIQILWENSWQPFAEFLSGVFGVSIEGISDL
                     LGGGLLATLGLLADAIKLVADGFTVFSDWCKENKEPILALITTWQTINFLSWAEQAGG
                     LAGAFSLLGSKVSLIVGGIKNLGLAIKALTFDKLVSFGETIYLNTLYAKDFVVNSGKT
                     IAQLGKTALELGKSALAWTAHAAKMGLATAAEFAHSVAAGVATAATWAFNAALAVLTS
                     PITWIIAAIAALIAIGVLLYQNWDTVVEFAKTAWQGLCDFISGICRAIGEFFSGLWTK
                     LQEIFEPIGQWFGEKFQQAWDAIVNIFSGIGEWFSGVFQGAWDAIVNIFTPIGSWFGQ
                     RWADVTSALANIGAWFTDIFQKAWTGLTNIFSKLGLWFGERWADVTSVLANVSSWFGN
                     MFTSAYNAVKNAFSSIGGFFSGVWSTVQSIFVNAGQKVGSAVGGAFKSAVNAVLGTIE
                     NVVNDFIGMINGVLGVVRNLPGLGWVGSVSTVSLPRLARGGIVDSPTIAMIGEAGKEA
                     VVPLENTGFIQTLGRVVSSAVVNAMAGISPQGGFSSDGDIVIQIAGHEFGRVAIQEIN
                     KEHERAGQTLLKI"
BASE COUNT         1137 a          993 c          732 g         1141 t
ORIGIN      
        1 acagaatcca gcccaatccg cttggattcc tgagcaagag aactacttgc gccagcattt
       61 cgcaaagctt cctcagcctt gcgcttagct tctttcaatg gcccgttgtc aaagctatta
      121 aagcgctgat tgatagtgtc agacagttct ctcttgactt cttcagctct ggctttggcc
      181 agttctactt gatcgttaaa gtcttttttg attttgtcga ccttttggtc aaaatcttta
      241 tctgctgctt caatctgcgc ttggattttc gcttcaaagc catcttgttg cttaatctgc
      301 ttggtaatcg taccctcgta agaatactgg gtatcgtttc cagccttact atctgcactg
      361 atacgacctc tcagaccacc tttaaagata aagctctgac ttaagacagg aactttaaaa
      421 gtctctttct tgttggtctg aatggttacc cactgcccaa cctcaagtaa caaatgtcct
      481 tggtagttga gattatacgg atagtaagtt aggtttttca gtttgtaata caagtcattt
      541 aaagcgctct gggttatgaa gacattatca agttccaaag accgacctgt tgtcataccg
      601 accgtcagag acttcttatc cgtcttacaa gtgataccag ctatctgata ctcgatttca
      661 ctcttggtca atccatgcaa gaagtaactg tcagcgttaa tcgtgatgtt ggactcggtc
      721 aaatcacgga tttccatctt tccttctcgg ttgaagaagc aagacatccc aatcatctga
      781 gtcatagcgc tcagcatatc cctgaacgaa agtttcttac cttcaggaac ttgctcgata
      841 tggtaacgca tagcgctgat tccgaaatag tcattcgcta actcaatgcc tgttttcagg
      901 cagatttcct gaataacctc tcgtacttca gctgggaaat gcaaatccgt cacgtactca
      961 cgattgagct taaacatacc gtccataagt tcaagtgtgg ttgtgttgcg gtttcggtca
     1021 atctcaatat cgttgatgaa gtattccccc atcttgaccc actggtaggt atccccaacc
     1081 agtagaccaa tctcagggtg cagggtatcc agcttattga acgtggtaat gatactggta
     1141 aaggtaattt taccgctacc agcgcaggtt ccaccaggct tataagtatc gcccttgatg
     1201 tagccatact caaaactagc ctctttgata tcccgtgaag catattcacc aacacgaata
     1261 gccagcgtcc tttccttggc aaacatggct ctgtcaaatt gtcgtctagt taaagcgtcc
     1321 attttcttac ctctctacca gattaaattt agcgccagac caaggtttaa gcttctcagt
     1381 aaaggtatag ctaggagctg tcctatcacc gacatagaaa gtctttgtga cttggccatc
     1441 catggggtct ggataagata cctcaaaaaa tttagatgat acagcatgta aaagctgact
     1501 tatttctccc tgagtcatca taccccattc acagtctagt ttgcgtttgg tcgtgatacg
     1561 gtcacgcacc atgtcgccat tggcattacg ccctgtctct ccatcgatat cttgaatacc
     1621 gacttgaaaa gatttgggag gcttcacagc caccccattg attgtcaatt gtgccattta
     1681 acctcctaaa tcttgagcaa ggtttgacct gctcgttcat gttccttgtt gatttcttgg
     1741 atagctaccc gtccgaactc atggcctgcg atttgaataa cgatgtcgcc gtcgctagaa
     1801 aaaccacctt gtggactaat accagccatg gcatttacta ccgcactgct gactactcgt
     1861 ccaagtgttt ggataaatcc tgtattttca agtggtacga ccgcctcttt accagcttca
     1921 ccaatcatgg cgattgttgg actatcgacg ataccaccac gggcaagacg agggaggcta
     1981 actgtgctta cactaccaac ccatcctaga ccaggtaagt ttctgacaac gcctaaaact
     2041 ccattaatca ttccgatgaa gtcattgact acattttcaa tcgttccaag aaccgcattg
     2101 accgcactct taaacgctcc acctacagcg ctaccaacct tttgtccagc attgacaaat
     2161 atgctttgaa ccgttgacca tacaccgctg aagaagccac caattgaact aaacgcgttc
     2221 ttgactgcat tataagcact agtaaacata ttcccaaacc aagaagatac attcgcaaga
     2281 acacttgtaa catctgccca tctctcgcca aaccataaac ctagtttgct aaagatgttt
     2341 gttagaccag tccatgcttt ttggaatatg tcagtaaacc atgccccgat attagccaaa
     2401 gcactagtca catctgccca acgttgtcca aaccatgagc cgattggagt gaagatatta
     2461 acgatagcgt cccatgcacc ttggaataca ccagagaacc actctccgat accagagaag
     2521 atgttgacaa tggcatccca tgcttgctgg aacttctcgc caaaccattg acctatcggc
     2581 tcaaagattt cttgtagttt tgtccataga ccactgaaaa attcgccaat agctcgacaa
     2641 ataccactaa taaaatcaca tagtccttgc catgcagttt tagcaaactc aacaacagtg
     2701 tcccagtttt ggtagagcaa gacaccgata gcaatcaaag ctgcgattgc tgcaataatc
     2761 catgttattg gacttgtcaa aactgctaac gctgcattaa aagcccatgt tgcagctgta
     2821 gcgactcctg ctgcaacaga atgtgcaaat tccgccgcgg ttgctaatcc cattttcgct
     2881 gcatgagcag tccatgctag agctgattta ccaagttcta aagcagtttt tcctagctgt
     2941 gcaattgttt tacctgaatt gaccacaaaa tcttttgcat ataaggtgtt caaatagatt
     3001 gtttcaccaa aactgaccaa cttatcaaat gtcaatgctt taatagcaag acctagattc
     3061 ttaatccctc caacaatcaa agagacctta ctacctaaca agctgaatgc tcctgcaagt
     3121 cccccggctt gttcagccca tgataagaaa ttaatcgttt gccaagttgt tatcaaagcc
     3181 aagataggtt ctttgttttc tttacaccag tcagaaaaaa cggtgaaacc atctgccact
     3241 aacttaatag catccgccaa tagtcccaaa gtggctaaaa ggccacctcc taataaatct
     3301 gaaattcctt caatactaac accgaatact cctgataaaa actcagcaaa aggttgccaa
     3361 gaattctccc agaggatttg tatgatatca atcagtccgt taaaagcatt agcaatagag
     3421 ttaatagcag gggctacatg ttcatcataa acacgactta agccatcgcc aaatttgtta
     3481 acagaccttt caatgctctc aaatacaggc gcaacagtat ctaataaact ttggaagatt
     3541 gatgaaattt taggagcgtt tgtcacaacg actttttcaa aatctttaaa caaacttcct
     3601 gctaatttac taccaacttc aacaatggta gatgtcaaac tcaacagagt tgacacaata
     3661 gcgctaccga tacgaaccgc accagttgag gtaatgacgt cgtagaaagc actagaaaag
     3721 tcctgagcga tgtttcctac tgcctcggca atgttaccaa tattatcaaa caaagcgact
     3781 agcgccttga taatgcgttc tttttgcctt ccaaggccat tggcaatact ttcggcaagg
     3841 aaaacaccga tacctagccc gatagtagct attgagcctg tcacttgccc taaagcataa
     3901 gcaattttct cagccattcg gttaaaggca ttcacaaccc ttgggtcagt ggcgatttct
     3961 cccattgtct tagctatttg gtctaaggca gtcttaatgc gtt
//
LOCUS       DAVKMJ010000086         3955 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000086 DAVKMJ010000000
VERSION     DAVKMJ010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3955
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.086"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..1322)
                     /locus_tag="VW348_002089"
     CDS             complement(<1..1322)
                     /locus_tag="VW348_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEU9746921.1"
                     /translation="MDALTRRQFDRAMFAKNRTLAIRVGDYASQDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVLEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINADSYFLHGL
                     TKSEIEYQISGITCKTDKKSLTVGMKTGRSLELDNVFMTQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFTFKGGLRGRISADSKAGNDTQYS
                     YEGTITKQIKQQDGVEAKVQAQIEAADKDFDQKVDKIKKDFNDQVELAKARAEEVKRE
                     LSDTINQRFNSFDNGPLKEAKRKAEEALRNAGASTLLAQEAKRIGLDSV"
     gene            complement(1327..1677)
                     /locus_tag="VW348_002090"
     CDS             complement(1327..1677)
                     /locus_tag="VW348_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746922.1"
                     /translation="MAQLTINGVAVKPPKSFKVGIQDIDGETGRNANGDMVRDRITTK
                     RKLDCEWGMMTQGEISQLLHAVSSEFFEVSYPDPMDGQVTKTFYVGDRTAPSYTFTEK
                     FKPWSGAKFNLVER"
     gene            complement(1686..3725)
                     /locus_tag="VW348_002091"
     CDS             complement(1686..3725)
                     /locus_tag="VW348_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746923.1"
                     /translation="MFDNIGNISEAVGNIAQDFSSTFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKISSVFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVAPAINSIANAFNGLIDIIQILWEGSWKPFAEFLSNTFGISIETVADL
                     LGGIILEALKLLADTIKLVTDGFTAFSDWCKENKEIISTIASVIGTLATVWQGIKFLS
                     WAEQAGGLAGAFELLSSKVSFIVSGIKNLGLALKALTFDKLVSFGETIYLNALYAKDF
                     VVNSGKTIAQLGKTALELGKSSLAWTAHTAKMGLATAAEFAHSVAAGVATAATWAFNA
                     ALAVLTSPITLVIAAIAALIGIGVLLYQNWDTVVEFAKTAWQGLCDFISGICRAIGEF
                     FSGLWTKLQEIFEPIGQWFGEKFQQAWDAIVNIFTPIGSWFGQRWADVTSALANIGAW
                     FTDMFQKAWTGLTNIFSKLGLWFGERWADVTSVLANVSSWFGNMFTSAYNAVKNAFSS
                     IGGFFSGVWSTVQSIFVNAGQKVGSAVGGAFRSAVNGVLGTIENVVNGFIGMINGVIG
                     MINKIPGVSLGGIGYVSLPRLARGGIVDSPTIAMIGEAGKEAVVPLENTGFIQTLGRV
                     VSSAVVNAMAGISPQGGFSGDGDIVIQIAGHEFGRVAIQEINKEHERAGQTLLKI"
BASE COUNT         1112 a          977 c          728 g         1138 t
ORIGIN      
        1 acagaatcca gcccaatccg cttagcttcc tgtgcaagca gggtacttgc gccagcattt
       61 cgcaaagctt cctcagcctt gcgcttagct tctttcaatg gcccgttgtc aaagctatta
      121 aagcgctgat tgatagtgtc agacagttct ctcttgactt cttcagctct ggctttggcc
      181 agttctactt gatcgttaaa gtcttttttg attttgtcga ccttttggtc aaaatcttta
      241 tctgctgctt caatctgcgc ttggactttt gcttcaacgc catcttgttg ctttatctgc
      301 ttggtaatcg ttccctcgta agaatactga gtatcatttc cagctttact atctgcgctg
      361 atacgacctc tcagaccacc tttgaaagta aagctctgac ttaagacagg aactttaaaa
      421 gtctctttct tattggtctg aatggttacc cactgcccaa cctcaagcag taaatgccct
      481 tggtagttga gattatacgg atagtaagtt aggtttttca gtttgtaata caggtcattt
      541 aaagcactct gggtcatgaa gacattgtcc agttccaaag accgacctgt cttcataccg
      601 accgtcagag acttcttgtc cgtcttacaa gtgataccag atatctgata ctcaatctca
      661 ctcttggtca agccatgcaa gaagtaactg tcagcgttga tcgtgatatt ggactcagtc
      721 aaatcacgga tttccatctt gccttctctg ttgaagaaac aagacatccc aatcatctga
      781 gtcatagcgc tcagcatatc cctgaacgaa agtttcttac cttcaagaac ttgctcgata
      841 tggtaacgca tagcgctgat tccgaaatag tcattcgcta actcaatgcc tgttttcagg
      901 cagatttcct gaataacctc tcgtacttca gctgggaaat gcaagtccgt cacgtactca
      961 cgattgagct taaacatacc gtccataagt tcaagcgtgg tagtgtttcg gtttcggtca
     1021 atctcaatat cgttgatgaa gtattccccc atcttgaccc actggtaggt atccccaacc
     1081 agtagaccaa tctcagggtg cagggtatcc agcttattga acgtggtaat gatgctggta
     1141 aaggtaattt taccgctacc agcgcaggtt ccaccaggct tataagtatc gcccttaatg
     1201 tagccatact caaagctagc ctctttgata tcctgtgaag cataatctcc aacacggata
     1261 gccagcgtcc tgtttttggc aaacatggct ctgtcaaatt gtcgtctagt taaagcgtcc
     1321 attttcttac ctctctacca gattaaattt agcgccagac caaggtttaa acttctcagt
     1381 aaaggtatag ctaggagctg tcctatcacc gacatagaaa gtctttgtga cttggccatc
     1441 catggggtct ggataagaca cctcaaaaaa ttcagatgat acagcatgta aaagctgact
     1501 tatttctccc tgagtcatca taccccattc acagtctagt ttgcgtttgg tcgtgatacg
     1561 gtcacgcacc atgtcgccat tggcattacg ccctgtctct ccatcgatat cttgaatacc
     1621 gactttaaaa gatttgggag gcttcacagc caccccattg attgtcaatt gtgccattta
     1681 acctcctaaa tcttgagcaa ggtttgacct gctcgttcat gttccttgtt gatttcttgg
     1741 atagctaccc gtccgaactc atggcctgcg atttgaataa cgatgtcgcc gtcaccagaa
     1801 aaaccacctt gtggactaat accagccatg gcatttacta ccgcactgct gacaactcgc
     1861 ccaagggttt ggataaagcc tgtattttca agtggtacga ccgcttcttt accagcttca
     1921 ccaatcatgg cgattgttgg gctatcgacg ataccaccac gggcaagacg aggtaggctc
     1981 acatatccaa taccaccaag ggatacgcca ggtattttgt taatcatgcc aataacacca
     2041 ttgatcatgc cgatgaagcc attgactaca ttttcaatag tcccaagaac accattgact
     2101 gcacttctga aagccccacc tacagcgcta ccaacctttt gtccagcatt gacaaatatg
     2161 ctttgaaccg ttgaccatac accgctgaag aagccaccaa ttgaactaaa cgcgttcttg
     2221 actgcattat aagcactagt aaacatattc ccaaaccaag aagatacatt cgcaagaaca
     2281 cttgtaacat ctgcccatct ctcgccaaac cataaaccta gtttgctaaa gatgtttgtt
     2341 agaccagtcc atgctttttg gaacatgtca gtaaaccatg ccccgatatt agccaaggca
     2401 ctagtcacat ccgcccaacg ttgtccaaac catgagccga ttggtgtgaa gatattaacg
     2461 atagcatccc atgcttgctg gaacttctcg ccaaaccatt gacctattgg ctcaaagatt
     2521 tcttgtagtt ttgtccatag accactgaaa aattcgccaa tagctcgaca aataccacta
     2581 ataaaatcac atagtccttg ccatgcagtt ttagcaaact caacaacagt gtcccaattt
     2641 tggtagagca agacaccgat accaattaag gctgcgattg ctgcaataac taaggttatt
     2701 ggacttgtca aaactgctaa cgctgcatta aaagcccatg ttgcagctgt agcgactcct
     2761 gctgcaacag aatgtgcaaa ttccgccgcg gttgctaatc ccattttcgc tgtatgagca
     2821 gtccatgcta gagatgattt accaagttct aaagcagttt tccctagctg tgcaattgtt
     2881 ttacctgaat tgacaacaaa atcttttgca tacaacgcat tcaaatagat ggtttctccg
     2941 aagctgacca atttatcaaa tgtcaaagct ttcaaagcta gtccaagatt tttaattccg
     3001 ctaacaataa aggaaacctt actacttaat aattcgaatg cccctgcaag tcctccagct
     3061 tgttcagccc aagacaagaa cttaattcct tgccacacgg ttgcaagcgt accaatcaca
     3121 ctagcgattg tggagataat ctctttattt tctttacacc aatctgaaaa agcagtaaaa
     3181 ccatcggtta ctagcttgat tgtatcagct agtaacttca atgcctctag tatgataccg
     3241 cctagtaaat cagcgacggt ttcaatactt atgccgaatg tgttagacaa gaactctgca
     3301 aaaggcttcc aacttccttc ccaaagtatt tgaataatgt caattagccc attaaaagca
     3361 ttagcaatag agttaatagc aggggctaca tgttcatcat aaacacgact taagccatcg
     3421 ccaaatttgt taacagacct ttcaatgctc tcaaatacag gcgcaacagt atctaataaa
     3481 ctttggaaga ctgatgaaat tttaggagcg cttgtcacaa cgactttttc aaaaccttta
     3541 aacaaacttc ctgctaattt actaccaact tcaacaatgg tagatgtcaa actcaacaga
     3601 gttgacacaa tagcgctacc gatacgaacc gcaccagttg aggtaatgac gtcgtagaaa
     3661 gtactagaaa agtcctgagc gatgtttcct actgcctcgg aaatgttacc aatattatca
     3721 aacaaagcga ctagcgccct ggtaatgcgt tctttttgcc ttccaaggcc atttgcaata
     3781 ctttcggcaa ggaaaacacc gatacctagc ccgatagttg ttattgagcc tgtcacttgc
     3841 cctaaagcat aagcaatttt ctcagccatt cggttaaagg cattcacaac ccttgggtca
     3901 gtggcgattt ctcccattgt cttagctatt tggtctaagg cagtcttaat gcgtt
//
LOCUS       DAVKMJ010000087         3747 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000087 DAVKMJ010000000
VERSION     DAVKMJ010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3747
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.087"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            158..385
                     /locus_tag="VW348_002092"
     CDS             158..385
                     /locus_tag="VW348_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746924.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            673..3570
                     /gene="nanA"
                     /locus_tag="VW348_002093"
     CDS             673..3570
                     /gene="nanA"
                     /locus_tag="VW348_002093"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEU9746925.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKEIDGKTYQILY
                     REGEKEAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
BASE COUNT         1284 a          621 c          846 g          996 t
ORIGIN      
        1 gttttaaaaa tgaggtataa taaatttact aacacttata aaaagtgata gaatctatct
       61 ttatgtatat ttaaagatag attgctgtaa aaatagtagt agctatgcga aataacagat
      121 agagagaagg gattgaagct tagaaaaggg gaataatatg atatttaagg cattcaagac
      181 aaaaaagcag agaaaaagac aagttgaact acttttgaca gtttttttcg acagttttct
      241 gattgattta tttcttcact tatttgggat tgtccccttt aagctggata agattctgat
      301 tgtgagcttg attatatttc ccattatttc tacaagtatt tatgcttatg aaaagctatt
      361 tgaaaaagtg ttcgataagg attgagcagg aagtatggta taaatagcat aagctgatgt
      421 ccatcatttg cttataaaga gatattttag tttaattgca gcggtgtcct ggtagataaa
      481 ctagattggc aggagtctga ttggagaaag gagaggggaa aattggcacc aatttgagat
      541 agtttgttta gttcattttt gtcatttaaa tgaactgtag taaaagaaag ttaataaaag
      601 acaaactaag tgcattttct ggagtaaatg tcttatttca gaaatcggga tatagatata
      661 gagaggatca gtatgaatcg gagtgttcaa gaacgtaagt gtcgttatag cattaggaaa
      721 ctatcggtag gagcggtttc tatgattgta ggagcagtgg tatttggaac gtctcctgtt
      781 ttagctcaag aaggggcaag tgagcaacct ctggcaaatg aaactcaact ttcgggggag
      841 agctcaaccc taactgatac agaaaagagc cagccttctt cagagactga actttctggc
      901 aataagcaag aacaagaaag gaaagataag caagaagaaa aaattccaag agattactat
      961 gcacgagatt tggaaaatgt cgaaacagtg atagaaaaag aagatgttga aaccaatgct
     1021 tcaaatggtc agagagttga tttatcaagt gaactagata aactaaagaa acttgaaaac
     1081 gcaacagttc acatggagtt taagccagat gccaaggccc cagcattcta taatctcttt
     1141 tctgtgtcaa gtgctactaa aaaagatgag tacttcacta tggcagttta caataatact
     1201 gctactctag aggggcgtgg ttcggatggg aaacagtttt acaataatta caacgatgca
     1261 cccttaaaag ttaaaccagg tcagtggaat tctgtgactt tcacagttga aaaaccgaca
     1321 gcagaattgc caaatggtcg agttcgcctg tatgttaatg gtgttttatc tcgaacaagt
     1381 ctgaaatctg gcaatttcat taaagatatg ccagatgtaa cgcatgtgca aatcggagca
     1441 accaagcgtg ccaacaatac ggtttggggg tcaaatctac agattcggaa tctcactgtg
     1501 tataatcgtg ctttaacacc agaagaggta caaaaacgta gtcaactttt taaacgctca
     1561 gatttagaaa aaaaactacc tgaaggagcg gctttaacag agaaaacgga catattcgaa
     1621 agcgggcgta acggtaaacc aaataaagat ggaatcaaga gttatcgtat tccagcactt
     1681 ctcaagacag ataaaggaac tttgatcgca ggtgcagatg aacgccgtct ccattcgagt
     1741 gactggggtg atatcggtat ggtcatcaga cgtagtgaag ataatggtaa aacttggggt
     1801 gaccgagtaa ccattaccaa cttacgtgac aatccaaaag cttctgaccc atcgatcggt
     1861 tcaccagtga atatcgatat ggtgttggtt caagatcctg aaaccaaacg aatcttttct
     1921 atctatgaca tgttcccaga agggaaggga atctttggaa tgtcttcaca aaaagaagaa
     1981 gcctacaaag aaatcgatgg aaaaacctat caaatcctct atcgtgaggg agaaaaggaa
     2041 gcttatacca ttcgagaaaa tggtactgtc tatacaccag atggtaaggc gacagactat
     2101 cgcgttgttg tagatcctgt taaaccagcc tatagcgaca agggtgatct atacaagggt
     2161 gaccaattac taggaaatat ctacttcaca acaaacaaaa cttctccatt tagaattgcc
     2221 aaggatagct atctatggat gtcctacagt gatgacgacg ggaagacatg gtcagcgcct
     2281 caagatatta ctccgatggt caaagccgat tggatgaaat tcttgggtgt aggtcctgga
     2341 acaggaattg tacttcggaa tgggcctcac aagggacgga ttttgatacc ggtttatacg
     2401 actaataatg tatctcactt aaatggctcg caatcttctc gtgtcatcta ttcagatgat
     2461 catggaaaaa cttggcatgc tggagaagcg gtcaacgata accgtcaggt agacggtcaa
     2521 aagatccact cttctacgat gaacaataaa cgtgcgcaaa atacagaatc aacggtggta
     2581 caactaaaca atggagatgt taaactcttt atgcgtggtt tgactggaga tcttcaggtt
     2641 gctacaagta aagacggagg agtgacttgg gagaaggata tcaaacgtta tccacaggtt
     2701 aaagatgtct atgttcaaat gtctgctatc catacgatgc acgaaggaaa agaatacatc
     2761 atcctcagta atgcaggtgg accgaaacgt gaaaatggga tggtccactt ggcacgtgtc
     2821 gaagaaaatg gtgagttgac ttggctcaaa cacaatccaa ttcaaaaagg agagtttgcc
     2881 tataattcgc tccaagaatt aggaaatggg gagtatggca tcttgtatga acatactgaa
     2941 aaaggacaaa atgcctatac cctatcattt agaaaattta attgggaatt tttgagcaaa
     3001 aatctgattt ctcctaccga agcgaaagtg aagcgaacta gagagatggg caaaggagag
     3061 atgggcaaag gagttattgg cttggagttc gactcagaag tattggtcaa caaggctcca
     3121 acccttcaat tggcaaatgg taaaacagcg actttcctaa cccagtatga tagcaagacc
     3181 ttgttgtttg cagtagataa ggaagatatc ggacaggaaa ttattggtat agctaaagga
     3241 agcatcgaaa gtatgcataa tcttcctgta aatctagcag gtgccagagt tcctggcgga
     3301 gtaaatggta gcaaagcagc ggtgcatgaa gttccagaat ttacaggggg agttaatggt
     3361 acagagccag ctgttcatga aatcgcagag tataagggat ctgattcgct tgtaactctt
     3421 actacaaaag aagattatac ttacaaagct cctcttgctc agcaggcact tcctgaaaca
     3481 ggaaacaagg agagtgacct cctagcttca ctaggactaa cagctttctt ccttggtctg
     3541 tttacgctag ggaaaaagag agaacaataa gagaagaatt ctaaacattt gattttgtaa
     3601 aaatagaagg agatagcagg tttttaagcc tgctatcttt ttttgatgac attcaggctg
     3661 atacgaaatc ataagaggtc tgaaactact ttcagagtag tctgttctat aaaatatagt
     3721 agattgaaat aagatgtgaa caactct
//
LOCUS       DAVKMJ010000088         3536 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000088 DAVKMJ010000000
VERSION     DAVKMJ010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3536
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.088"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(232..843)
                     /gene="rpsD"
                     /locus_tag="VW348_002094"
     CDS             complement(232..843)
                     /gene="rpsD"
                     /locus_tag="VW348_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEU9746926.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1038..2090)
                     /locus_tag="VW348_002095"
     CDS             complement(1038..2090)
                     /locus_tag="VW348_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEU9746927.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2087..2785)
                     /locus_tag="VW348_002096"
     CDS             complement(2087..2785)
                     /locus_tag="VW348_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEU9746928.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQI"
     gene            complement(2952..>3536)
                     /locus_tag="VW348_002097"
     CDS             complement(2952..>3536)
                     /locus_tag="VW348_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HEU9746929.1"
                     /translation="PWSDNGDAKNPALSPLGENVKTKGQYFYQLALDGNVAGKEKQAL
                     IDQFRANGTQTYSATVNVYGNKDGKPDLDNIVATKKVTIKINVKETSDTANGSLSPSN
                     SGSGVTPMNHNHATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPN
                     TGETQTSMASIGFLGLALAGLLGGLGLKNKKEEN"
BASE COUNT          977 a          789 c          683 g         1087 t
ORIGIN      
        1 tcacaataag agagaacttt tttacgaaaa tctattgaat atgccataaa agattatacc
       61 acattgtgta ctatttttgg ttcattttac tatatcactt tggactatat cggtctagtt
      121 atgtctcaac gattatagct ggatactaag agaaatcaaa aaagcactaa gggagaacgt
      181 cccaaagtgc ttaatatcaa ggcctcaaag cctgtcttat tcaataaaat attacaacat
      241 cttgttgtag aattcaacga caagtgcttc gttgatttct gggttgattt cgtcgcgttc
      301 tggcaagcga gtcaatgaac cttccaactt ttcagcgtcg aatgatacga atgctggacg
      361 tccaagagta gcttctactg cttcaaggat tgctggaact ttcaatgatt tttcacgaac
      421 tgagatcact tgacctggag ttacgcggta tgatgggata tcaacgcgtt tcccgtcaac
      481 aaggatgtga ccgtggttta cgaattgacg agcttgacga cgagtagtcg cgagaccaag
      541 acggtaaaca acattatcca aacgacgttc caaaagaagc ataaagttga aacctaggat
      601 tccacctttg atttttgtag cttgtacgaa caagttacgg aattgttttt cacctacacc
      661 gtaagtgaaa cgaagttttt gtttttcagc caattgcaaa ccatattctg acaatttaga
      721 acggttgttt ggtccgtgtt gtcctggtac gtagttacga cgtgccaatt ctttacctgt
      781 acctgtaagt gaaaggccaa ggcgacgagc ttgtttccaa gatggtcctg tataacgtga
      841 catatgaatg tcctcctgat ataaataata tttcggtgga aatagtcact tagaaagccc
      901 tgattcgtgc agatgccctt cgcctaaaca gccaaggtta cttgtcataa gacacctgtt
      961 gacgagcttc atgctttcct gctgatattt cacacaaaat ccattttacc atgaatagct
     1021 ggatttgtaa aggggtttta ggctttattt tcactaccag agaggttgag aacgagggta
     1081 aaggtacttc ctagaccgta ctggctgctg actgtgattt ccccacccaa ttgatgggcc
     1141 aattcacgcg caatcgcaag tcctaatcca tgaccacctg tcttcatgtt acgcgaagtt
     1201 tcgacacgat aaaggcgttt gaaaatattt tccaaatcct ctggggcaat gccctgccct
     1261 tcatcggtca cactgattga aagctggtcc ttctccagct tagccaccac ttccagcttg
     1321 gttcctggag cagaatattt aaaagcgtta tcgaccagat tcaccaagat acgagaaagc
     1381 ttagcataat ctccctcaat ccgggcagac tctgggatta cctgcaagtg gacatctctt
     1441 ctctcctgct caatcaaaaa ctgaaattca ctcatgcact caattaagag cttgtccaga
     1501 aaaatactgt ctttactggt agtttccacc tgatttctag ctgtgtttag ggtcaaaaaa
     1561 ttcaactcct caaccagttt attgagcctc tccgtctggc gtccaatggt tgctagataa
     1621 tgagcttgct ccgactcctt gataatccca tccaaaatcc cttctaccgt cgcttggatc
     1681 gaagtgatag gggtcttaat atcatgcgac aactgggcaa tcatcaagcc cttttctcgt
     1741 tcgctttctt ccaaggaatc aaagcttacc tgcaaatcat gggacatctc attaaaagtt
     1801 tgccctaatt gctgaaattc tacaggacct tgaacctcca aatttgaagg aaaatccttg
     1861 gccgctaccc gcttggcatg ctccttgagt ttgcccaacg acgtaaagac tggcaatagg
     1921 agaaagagac taatcccagc accgacaagg ctggcaacga tggtcatccc aagcaaaaag
     1981 taaatctcgc ctttcgcaat cagcattttt tgaacagccc aaaaaacaac caaaatggtt
     2041 aagagggttg aaataatata tccaaccaaa atataacttt ttagtttcat atttgtcctc
     2101 tcggtttctc tatcttatat cccaaccccc aaactgtctt aatagtggga gtttggtcac
     2161 tactatattt tgccagctcc tgtcgaagag catggatatg cacattcaag gtattggtgt
     2221 catccacgta gtcttctttc cagatctttt catagaggtc tgtcttggag aaaactcgct
     2281 ctggattgct agctaaaatc cacagcaatt caaatgattt aacagttaaa tccagcattt
     2341 cttctcctat ttgaacttca tgactactat gattcatttt tagattgcca agggaaatca
     2401 gctctgtttc gcccccacga tgaaggcggc gcaaaatatt gtggacacgc aaaaccagct
     2461 cacgtgggct aaaaggctta gcaataaaat catctgctcc caagctcagg ccgtaaatct
     2521 tgtcctgttc actggtctta gcagtaataa ataggaaagg ctgctctggt gataagtatt
     2581 gaacctcact gattaaatca taaccatcca tccgaggcat catgacatct gtgataatca
     2641 aatcaatcgg ttttttcttg aacagctcta gcgcttccag tccatcatgg gctaccaaga
     2701 cctgataacc tgcctgaatt aagtatctct gatgaatatc tgtgatttct acctcgtcgt
     2761 caacgagtaa aattgtcttt cccatctgtc tctcctttga taaaaacagt gctatactgc
     2821 tttaagtata acactatttt tattgtttta cgatgatttt aatctgctat tgaaagaaag
     2881 tcctgattgc tgattgagtt gttaaactaa tcttagtcag cccactatcc atcatttatt
     2941 tccttagctg attagttttc ttcttttttg tttttcaaac ctagaccacc gagtaaacct
     3001 gcaagcgcaa gcccaaggaa accaatactt gccattgatg tttgagtctc accagtattt
     3061 ggtagcatag ctttatcctc tgacatcatc gtatcagaca tcttgttagc agaagcagcc
     3121 atgttttcac ctgccatcgt gttggtagaa cttgtcatgg tgtcagcagg catgctatct
     3181 gtagtacctg tagcatgatt gtgattcatc ggagtcacgc cagaaccaga gttagaaggt
     3241 gataatgaac catttgctgt gtctgatgtt tctttaacat ttatcttaat agtgactttt
     3301 ttagttgcta cgatgttgtc caaatctggt ttaccgtctt tgttaccata gacattgact
     3361 gtagcgctgt aagtttgagt accatttgct cggaactggt caatgagcgc ttgtttttct
     3421 ttgccagcta catttccgtc caaggctaat tgatagaagt attgaccttt ggtcttcacg
     3481 ttttcaccta gtggagatag agctgggttt ttagcgtcgc cgttatctga ccatgg
//
LOCUS       DAVKMJ010000089         3142 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000089 DAVKMJ010000000
VERSION     DAVKMJ010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3142
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.089"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            33..446
                     /gene="ndk"
                     /locus_tag="VW348_002098"
     CDS             33..446
                     /gene="ndk"
                     /locus_tag="VW348_002098"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEU9746930.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEIIQNVVHGSDSEESAKREIALWF"
     gene            complement(1392..2024)
                     /locus_tag="VW348_002099"
     CDS             complement(1392..2024)
                     /locus_tag="VW348_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEU9746931.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLVYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            complement(2026..2793)
                     /locus_tag="VW348_002100"
     CDS             complement(2026..2793)
                     /locus_tag="VW348_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEU9746932.1"
                     /translation="MSQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRISSQD
                     ERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQSILFWIDAVQ
                     NYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLGFVASVFLQVE
                     IGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            complement(2844..>3142)
                     /locus_tag="VW348_002101"
     CDS             complement(2844..>3142)
                     /locus_tag="VW348_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746933.1"
                     /translation="NVLRYDLNMLQLEYKNEQSWDSFIDNVNLIELEERIQTTIGIKQ
                     INTHNIITIAREGYSQNYLPNTSENTYNSLQVSLVGVLLLFISMVNILWAKKSK"
BASE COUNT          993 a          598 c          533 g         1018 t
ORIGIN      
        1 ataaaagaaa gaagctgaca aaggagacgg gtatggaaca aacattcttt atcatcaaac
       61 cagatggtgt aaaaagaggg ctagtgggtg aagtgttaaa gcgcatcgaa caacgtggat
      121 ttacaatcga aaaattggag tttcgttcac aggtttcaga agagttgatt gaccagcact
      181 atcaggactt ggttggtcag agtttttacc caccgattcg tgaattcatg acttcaggtc
      241 cagttcttgt gggtgtcatt tctggtccca aagtaatcga aacttggcgg accatgatgg
      301 gtgcaactcg tccagaagaa gctttaccag gcactattcg aggtgatttt gcaaaagctg
      361 ctggagaaaa tgagattatc caaaatgttg tacatggttc agattcagaa gagtcagcta
      421 agcgagaaat tgctctttgg ttttaagagt ggattggctc aatcaattgg ttaaaagctc
      481 atttgaatag aaagtatagt caattagttt aagacatgac gcatgatatc aaacttttta
      541 gtttttgata tggtgcgttt tttgattaag tgactattag tttgtctcgc tccgttaggt
      601 gcgagacaaa aaaaacaccc gctatgcggg tgtgcgtcga aggttatacc aaaaaaactc
      661 catacgcgat acaataaagg tgttcaatcc aattgtaaag cgaaaggaga aaaatatggc
      721 acaaaaggtt cttttatcct gttcttgttt caattgacta tatttctata ctttttcttc
      781 ctttctctgt gaaaatcgca agtttttccc accttttctc aatactgaaa caacatcttt
      841 ccagaacttc aataatttct ttttgtgtta aatcattatt taactaaatc tttggaggca
      901 atacgttttc aaagctactt ttttaccata ggttttgagc cttcaacaca gattactaag
      961 ccaaaaatgc tctaaatttt tgaaattcta acaaattcca ctcaacttta tcatcatctt
     1021 tgactttcac aatatcttcc tcaaaataac atggaataaa gatagttttc ttttaaaacg
     1081 gttgtaggag gaaaatctct cctacactat tattgattct gagagaaaat tgcaaaatat
     1141 catctaccaa actttcaatt attaagattt tttgcagttt atctgaatta gaatcgcaag
     1201 gcttctcaat aatataattg tcgaattttt tcattctaac ttcctctcca ttatttcttc
     1261 ctttatcaag aaaaagttac ctcaatatta ataaagtaca attctaaatt aagtacaatt
     1321 ctaaattaac tccaattctt gattcatgat aatatttcag taactcatcg tgcaattaaa
     1381 aacaaggatt tttatttcag atgatccatc gtgaacactt catcagccat ctcccaaatt
     1441 gccggattat gtgttgcgat aatgattagc ctattatcat ctcgaagaga tagcaaaatc
     1501 tccataatca actgagaggt tgctgggtct attgaagctg ttggctcatc tgccagaata
     1561 aagggtggat tctttaagat aatttttgcc aaggcaaccc gttgcgattc tccgcccgat
     1621 aactcaaaga tgcgcttatc taggtcaaga taaaccaggc cgacctgttc taaagcctgc
     1681 ttctgcctca accgctgttc cgaccgactc aacttttgac caatgagacc tagcttaagg
     1741 ttttcttcaa tactttggtt ttcaattaag ccaaagttct ggaagaggta gcccaattcg
     1801 tgacggaaaa aatcacttga tttataattg gccaagtctt tacctcggta aaaaatcgtc
     1861 ccatcataag gttctaattt cccaatcatg ttcatcaagg ttgtttttcc gctaccactt
     1921 gaaccaatta aggcatagac ttttccagcc tcaaatgtca ttgaaagatt cgaaaataac
     1981 tctcgttctc caaaagattt actcacctgt ttaagttcaa tcatattaac ctcccttcaa
     2041 aacaagcatg gacatcttgt tttctttctg catttggaca tgtaactgta aaagagatag
     2101 accagtaaag agtaacaaga ctaagaaagc aactcctatc tctacctgaa gaaatacact
     2161 cgcaacaaat cccagtaaaa acacacccag ttgagcaaag agataagtgc gatggatttc
     2221 taagaacctg agacctgcaa tgcgtttgat aaaaatggca cgtctaaatt cttcaaagta
     2281 gagcctattc atagtgttaa acaacaagat tgaagttgca atcccaagca cagctcctgc
     2341 tagcattacc caacgttccc tctggatatt atccaataat gtgatgtagt tgtggtaacc
     2401 tgtttgcatt tctgagaccc aattttcaat gccttgtctc tggataagct cctgggcatc
     2461 agacaattga ttaaagagaa cgtagttctg tactgcgtct atccaaaaca aaatggactg
     2521 tggaccagtt gattggggtg ttataacaat gatgattgga tctttcaaaa actgctggta
     2581 agaaataggg gtcgtattat acacaaaacg atcctgacct gattctaaat aacctaccgt
     2641 agcagtcatt tgctgtcgtt catcttgact agatatgcga ctggttaagt cgtcttcaaa
     2701 aacagattta taatgttctt cctctgaacg gaggtgttca ggcagcaata agacaaactc
     2761 ccctacatca aggtgattca tcttttgact cattttagtt gaactgtagg acttactttt
     2821 tcagagggct ccaaatttta ttttcattta ctttttttag cccataaaat atttaccata
     2881 cttataaaaa gtagtaatac tccaactaaa ctgacttgta atgaattata tgtattttct
     2941 gaagtgttag gtaaataatt ttgagagtac ccttctcggg caatagtaat aatattgtgt
     3001 gtgtttattt gtttaattcc aatagtagtt tgaattctct cttccaactc aattaaatta
     3061 acattatcta tgaaactatc ccaactttgt tcatttttat attctaattg taacatattc
     3121 aaatcatatc tcaatacgtt tg
//
LOCUS       DAVKMJ010000090         3011 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000090 DAVKMJ010000000
VERSION     DAVKMJ010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3011
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.090"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            93..275
                     /locus_tag="VW348_002102"
     CDS             93..275
                     /locus_tag="VW348_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU9746934.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            285..650
                     /locus_tag="VW348_002103"
     CDS             285..650
                     /locus_tag="VW348_002103"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEU9746935.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            647..1825
                     /locus_tag="VW348_002104"
     CDS             647..1825
                     /locus_tag="VW348_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEU9746936.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     "
     gene            1994..2546
                     /locus_tag="VW348_002105"
                     /pseudo
     CDS             1994..2546
                     /locus_tag="VW348_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1138 a          443 c          518 g          912 t
ORIGIN      
        1 agaaatgacc gaattagaaa gaaaaaatcg aaaaattagc taagaaatat tctgataact
       61 taaacatcaa agttcaagag agagttcgtg aaatggcaaa tgataataag agccattatt
      121 tgatatacag agttttaggt atttcatttg aagaaggaga aaatatcgat ttgtatcaaa
      181 ataaaggtcg ttttttatac aaatatgctg gttcattttt agaagaagct gcagtactat
      241 cctttaacga aaaatttggt acagaaaata cttaaaaagt taacattcct aattctgaaa
      301 gtacaaaacc taagactttt gaaattgatt gtttagtcgg agaaaaacac gcatacgaaa
      361 taaaatggtg ggatgcaact acagatggag accatataac taaagaacac actagaataa
      421 aagttattca taacaaagga tatataccaa ttcggttaat gttctactat ccaaatagaa
      481 ctcaagctat aaaaattcag caaactttag aaacattgta taacggtatt ggagggaaat
      541 attattatgg agattctgcc tgggaacatt taagagcagt gaccggtatt gatttactta
      601 gtattctaac agatattgca aataaaaaaa caggggtaaa atcaaaatga cagtattaaa
      661 aggagataac ttagaaatat taaaaactat tgaatcctca agtattgatt taatctatat
      721 ggaccctcct ttctttacac agaaaaccca aaaattatct aataacaaaa atattatgta
      781 ttcattcgaa gatacgtgga cttcgattga ggattacaaa gaatttttgt ctgtaagatt
      841 agaagaatgc aaaagagtgc taaaaaatag tggcagtatt ttcgttcatt gtgataaaat
      901 tgcaaatcat catattagat taattttaga taatatcttt ggagcagata tgtttcaaag
      961 cgaaattata tggaactata aacgatggtc taattcaaaa aagggattat tgaacaatca
     1021 tcaaaacatt tacttttatt caaagtcaaa agattttaaa tttaatacaa tttttacaga
     1081 gtattcttct actacaaata tcgaccaaat actagtggaa cgaaaacgag atggaaactc
     1141 taaaactata tataaagttg ataataatgg taactatatt ctagcaaaag agaaaaatgg
     1201 agttcccctt tcagatgttt ggaatatacc atttcttaat ccaaaagcta aagaaagagt
     1261 aggttatcct acacaaaaac ctattctgtt attagaacaa attataaaga ttgctactga
     1321 taaaaatgat atagttttag acccgttctg tggaagcgga actactttag tagcctccaa
     1381 gattttgaat agaaattata tggggattga tttatctgag gaagctatca atataactca
     1441 gcaacgtctg gaaaatgtta taaaaacaag ttcaaattta ttgaataaag gaatcgaagc
     1501 atatagaacc aaaactgagg aagaggaaaa cattcttaaa ttattacagg caaaaattgt
     1561 tcaaagaaat aaaggaattg atggtttttt acctaaacat tttcaaaaaa aaccgatacc
     1621 tataaaaatt caaaaaaata atgaatgtct gaatgagagt atctctttat tacagaatgc
     1681 tataaactcc aaaaaacttg attttggagt agttataaaa actcattcag ataatttatt
     1741 atttgatttt gatacgattc ctgaaaatat aatagtagtt gaccattttg aacttacaat
     1801 cgaaaaatgg ttaagtaaaa gttaacagtt actatagttt gcaaattatt tacagaaaga
     1861 acaagaattc ctaggagatt attctggcta tgttcattgt gacatgttgc ggcagtaact
     1921 taggacttta gtcctctagt tctgcctatg cgatagcagt ccaaagttta ggagtaaggc
     1981 gacgctaagc ttggtaaact gcgaacagct agaagcttat cgtcaactgg aagaagctgc
     2041 acttgttgga tgttgggcgc atgtgagaag gaagtttttt gaagcgaccc ccaagcaagc
     2101 agataaatca tccttaggag ctaaaggttt agcttattgt gatcagttat tttccttgga
     2161 aagagactgg gaggctttgc cagctgatga acgactacag aaacgtcaag aacatctcca
     2221 acccctaatg gaagacttct ttgcttggtg ccgccgtcag tcagttttag caggttcaaa
     2281 actaggaagg gcaattgaat acagcctcaa gtataaagaa acctttaaga ccattttaaa
     2341 agacggacat ctggtccttt ccaataatct agctgaacgc gccattaaat cattggttat
     2401 gggacggagt aaaagagtcc agtggactct tttagcctga gctcagttta aaaaagcgag
     2461 ggtggttatt ttctcaaagt tttgaaggag ctaaagcaag agctattatt atgagtttgt
     2521 tggaaacagc taaacgtcat caattatagt gcgttgaatc tataacagta cgcatcgact
     2581 gctaaaatat ttctataaat caattttcct ttcctaatcg atttgttcat atcttatttc
     2641 aatccattat aaatagcgag aaatatctat cctatcttct agaatgtctt ccaaacgagg
     2701 aaactctcgt aaacaaagag gttttagagg cctatttacc gtggactaaa gttgtacaag
     2761 aaaagtgcaa ataagaaatc tccagattag gaactatccg tgagttcact aatctggaga
     2821 tttttcaata tacttcgtta ttgggcggtt acaatttatt atatgaaaat cccatatcat
     2881 tctccaattc tatattttac ctttctaaat gtatagatta actacctaat tatatcatat
     2941 aacgcagatt cctttcaatc gtatgattta ctgcattaaa ttaagtaaaa aaataaaggc
     3001 agtccgaaga c
//
LOCUS       DAVKMJ010000091         3008 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000091 DAVKMJ010000000
VERSION     DAVKMJ010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3008
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.091"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(27..1382)
                     /gene="rlmD"
                     /locus_tag="VW348_002106"
     CDS             complement(27..1382)
                     /gene="rlmD"
                     /locus_tag="VW348_002106"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEU9746937.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
     gene            1420..2196
                     /gene="recX"
                     /locus_tag="VW348_002107"
     CDS             1420..2196
                     /gene="recX"
                     /locus_tag="VW348_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEU9746938.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDENIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            2285..2818
                     /locus_tag="VW348_002108"
     CDS             2285..2818
                     /locus_tag="VW348_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEU9746939.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
BASE COUNT          968 a          545 c          536 g          959 t
ORIGIN      
        1 cttttcaaac tttgtcaact acttttttaa acttttttta ttaattttac aacagcttca
       61 gttcgagctg tatgtgggaa catatcgacc gactggatat aatgaagatc atagacttct
      121 actaagcgta ccaaatcacg agccaaggtc gaaacattac aagaaatata aaccattttt
      181 tctggtacat aagtaagaat agtatctaat aacttatcat ccagacctgt acgtggtggg
      241 tcaacaatca aagcatctgc tcggtagcct tccttgtacc aacgaggaat aatctcttct
      301 gccgttccag cttcataatg agtattgtca aatcccattc ttttagcatt tcgcttggca
      361 tcttcaatag cttctggaat aatatccata cctctgagtg tttttacttt ctttgcaaag
      421 gcaaatccaa tcgttccaac tccacaataa gcgtcaatca aatggtcttc tttatcaaca
      481 tccagcgctt ttactgcttc gctatagagg acttctgttt gctcaggatt tagttgataa
      541 aaagctcgag gggatagtga aaattcataa ttgagtacac cttcttgaat actctcttgc
      601 ccccagataa tctctgtctt ttcaccatat atctcactgg ttttagctgt atttgtatta
      661 acagctactg tcacaacttc tgggaaatct ttaaccaact cttttaccaa ttgagttaaa
      721 ttaagctggc ggtttgtaac aataataatc tgaacctgtc cggtctttct cgcgcgtcgg
      781 accataatag tacggacacc tagaactttt ctctcatccg tgattggaat ctggtgataa
      841 gtaagtaatt ctgctaagcg attagcaatc acttgggttt ccttatcttg taccaggcag
      901 tctttcaact ctactaaata gtgagagttt tgtgcatata agcccgcctt gacctgattt
      961 ttaaattttc gagtctgaaa ttgtaactta gctctgtaat attttggttc ctgcattcca
     1021 atagttggac gaatttcata attttcatat cctgcaggag caaatttttt cagcgcttga
     1081 tgaagtaagt ccgtcttgaa ctccagctgc ttatcataat gcaggtgcat gatttggcag
     1141 cctccgcatt cattataaat agtacaagat ggcacaattc gaaatttaga cttcttgttg
     1201 accttcagta attttgcttc aacaaagttg cgtctaatag aagtaatctg acaatagata
     1261 tcttcgcctt tgagagctcc aggtacaaag actaatgttt tttggtaaaa gccgattccc
     1321 tcaccattaa ttcccatgcg tttgattttt aatggtattt tttgtttcac tttcagattc
     1381 atacccctat cttatcacat tttgagttat aatagagcta tgaaaatcac aaaacttgaa
     1441 aagaaaaaaa gactctatct gatggagctt gataatggcg acaaatgcta tatcaccgaa
     1501 gatacaattg ttcgttttat gttatcgaga gataaggtga taagcgaaga ggaattgaaa
     1561 gagattcaag actttgctca attttcttat ggtaagaatc tggccctcta ccacttatcc
     1621 tttaaagcac gcactgaaaa agaagtcaga gaatatctga aaaaatacga tattgatgaa
     1681 aacatcgttt ctcaagttat tgctaatctt aaagaagata agtggattaa tgatggtcag
     1741 tacgcttatg ctatcatcaa taccaatcaa ctttcaggag acaagggtcc ttatgtgctg
     1801 actcagaaac tagctcaaaa agggatttca aaatctacta tagaagagaa cttgaaagaa
     1861 tttgattttt ctgaagttgc tcaacgtgta gccaataaac tattgaaaaa atatgaggga
     1921 aaacttccag ctcgtgccct gcaagataag attatccaga acttgactaa caagggcttc
     1981 tcttattctg atgctaaaat tgcctttgac gacttagata gccaagttga ccaagaaacg
     2041 actcaagaac tcatcttcaa ggaacttgat aagcaatata ctaagtatgc tcgaaagtat
     2101 gaaggatacg aactgaagca gcgtttaact caagttttag cacgaaaggg ctacgatttt
     2161 tcggatatag caagcgctct tagagaatat ctttaatatt tccaagtgaa attcacagat
     2221 tttaggtaat tttatggtac aatagtaaat gataaactta taaattgtag aaagttggtt
     2281 agttatgaag cttccaaaag aaggcgactt tattacaatt caaagttata agcatgatgg
     2341 gagtctccac cgaacttggc gggacaccat ggtactaaaa acaacagaaa acgccattat
     2401 tggtgtcaac gatcatacac ttgttaccga aagtgatggt cgtcgttggg tcactcgaga
     2461 accggctatt gtttactttc acaagaaata ttggtttaat atcattgcca tgattcgtga
     2521 taatggaact tcttactatt gcaatatggc tagcccctac tatctggatg aagaagcact
     2581 gaagtatatt gattacgatt tggatgttaa aatttttaca gatggggaaa aacgtctctt
     2641 ggacgttgaa gagtacgagc gtcacaaacg caaaatgaat tattctgatg acttggacta
     2701 tattttaaaa gaacatgtca aaattcttgt tgattggatt aacaatggac gtggtccttt
     2761 ctcagaagcc tatgtaaaca tttggtacaa gcgctatgta gaactaaaga atcggtaaag
     2821 ttgtcaaagg tcaggaacaa aatcctgacc tttttttggt agtataaaat aaattgtgta
     2881 aacacaaaaa ggaataaatc tattatagca gagttacaac acattactag aaagagattt
     2941 atgcaaaatt cgtaaaatat ataaaacaaa tagatatact gttatttttt aatgtcttta
     3001 ttccttgt
//
LOCUS       DAVKMJ010000092         2989 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000092 DAVKMJ010000000
VERSION     DAVKMJ010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2989
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.092"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..135)
                     /locus_tag="VW348_002109"
     CDS             complement(<1..135)
                     /locus_tag="VW348_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9746940.1"
                     /translation="MENFGAVLKDIRISKNFRLKDLSCNEISESTISRFENGITKLSI
                     N"
     gene            229..1449
                     /locus_tag="VW348_002110"
     CDS             229..1449
                     /locus_tag="VW348_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="caspase family protein"
                     /protein_id="HEU9746941.1"
                     /translation="MKKILLSTVALLSLVASLLANNPVSAQESSSQATYSKSSGSWIK
                     SGNRWWYKHSDGSYTTNGWEKINGTWYYFDSEGWMKTGWIKEYGKWYYLDDSGAMKTG
                     WCLVSGSWYYLNSSGVMQTGLQTINGKQYYLAAGGAMQTGWHNIGDDTYFFANSGENQ
                     NINRRALVLGETSTRAVPIADVNAMEKVFNNQNFSEVVRFPDRTKSEIIAKMQELFES
                     SSEGDVNYLYFTCHGGRDGRIYIGSDGLAFSGWELASVLKQYKGKFVVMLDCCHAGTI
                     ISKDNTGEGNEGASTEYFDLDEFVSGFSNMDGNEKSGEMIDSKFLVLCSSRGAEYSSG
                     GSLSLATKYWSLGSGWNPLQNSQAYLAADQNNNRRITLNELYTYSREQVLKQNSNQHI
                     EVYPDNSQFVLFKK"
     gene            1462..2643
                     /locus_tag="VW348_002111"
     CDS             1462..2643
                     /locus_tag="VW348_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEU9746942.1"
                     /translation="MKVSKKITLFSLSFAGFVLLTLPQAGKAFELKEDWAFKGGIRYE
                     NGKVSKINNGYEVNIKVLDLPSTSAIEWTVRLNGEKQNTNFLAEERTVSKTEDKGRFL
                     HFYIPYGYRGDIVVEAKSGNEVKTWSTKVVDDVYSDSAKSGYFILDGEQILESSWDSV
                     NESYIATLPTVTSGKTVVAWREKGTLNLIKPGRIARQYNSSGSYVELSPIFETASWLK
                     SNQNWYYQKQGQLVQNSWIKDQGSWYFMDDEGVMFNQTWLHQGGSWYAFKSSGAMISA
                     DWLYDNGSWYYLKDSGSMVTGWLKNGGSWYYLNKSGSMATGWIKDSGTWYYLKNSGSM
                     ATGWVKDSGSWYYLKNSGSMATGWVKDNGKWYYLASSGNMLRNTRTPDGYYVDGSGAW
                     K"
BASE COUNT         1019 a          395 c          627 g          948 t
ORIGIN      
        1 attaatagat aattttgtaa tgccattttc gaaacgagaa atagttgatt cactaatttc
       61 attacatgat aaatctttaa ggcgaaaatt ttttgaaata cgaatatcct ttaaaactgc
      121 tccgaaattt tccataatgt tcctcttcca tttctgcaaa aaataaaacg cttgtttttt
      181 atttatgata tgattataca aaaataaaat agaaaggaca ataatatcat gaaaaaaatt
      241 ttattgtcaa cagttgcttt attaagctta gtagcatctc tgctagcaaa taatccagtt
      301 tctgctcaag aatcatcctc tcaagcaact tatagtaagt caagtggaag ttggataaaa
      361 tctggtaacc gttggtggta taagcattct gatggttctt atactacaaa tggatgggaa
      421 aaaataaatg gtacctggta ctattttgat agtgaaggtt ggatgaagac aggttggatt
      481 aaagaatatg ggaaatggta ttacctagat gatagtggtg ctatgaaaac tggatggtgt
      541 ttggtttctg gtagctggta ttatttaaat agtagcggtg taatgcaaac gggactacag
      601 actatcaatg gaaaacaata ttatttagct gccggcggtg ctatgcagac aggttggcac
      661 aatatcggag atgataccta tttctttgct aatagtgggg aaaatcaaaa tatcaatcgt
      721 cgtgctttag ttcttggtga aacatcaacg agagcagtac ctattgcaga tgttaatgct
      781 atggaaaagg tttttaataa ccaaaacttt agtgaagttg ttcgtttccc agatagaaca
      841 aaatccgaga taattgcaaa aatgcaagag ctttttgaat cttctagcga aggcgatgtg
      901 aactatcttt actttacttg tcatggagga agagatggaa gaatctatat tggtagtgat
      961 ggcctagcat tttctggttg ggaattggcg tccgttttga aacaatacaa aggtaagttt
     1021 gttgttatgc tggattgttg tcatgctgga acaattattt ctaaagataa tacaggtgaa
     1081 ggcaatgaag gagcctctac ggaatatttt gatttagatg aatttgtatc aggattttct
     1141 aatatggatg gtaacgaaaa atcaggtgag atgattgact ctaaattttt agtattatgc
     1201 tcatcaagag gtgcagaata ctctagtggt ggatcattaa gtttagcgac taaatattgg
     1261 tctttaggtt caggatggaa tcctctacag aattcacaag catatttagc agcagaccaa
     1321 aataataatc gcagaatcac attaaatgaa ttgtatacat actctcgtga acaagttttg
     1381 aaacaaaatt ctaaccagca tattgaagtt tatcctgaca acagtcaatt tgtgttattt
     1441 aagaaataag ggggcaataa aatgaaagta tcaaaaaaaa ttacactatt tagtttgtct
     1501 tttgcaggtt ttgttttatt gactttacct caagcaggaa aggcttttga acttaaagaa
     1561 gactgggcat ttaaaggtgg cattcgatac gagaatggga aagtcagcaa aattaataat
     1621 ggatatgaag taaatattaa agtgttagat ttacctagta ctagcgcaat cgaatggaca
     1681 gttagattga atggagaaaa gcaaaatact aacttcttag cggaggaaag aactgtatct
     1741 aaaactgaag ataagggacg tttcttgcac ttttatatcc cctatggata tcgtggggat
     1801 attgtagtag aggctaagag tggaaacgaa gtgaagactt ggtctactaa ggtagttgac
     1861 gatgtttatt cagattctgc taagagtggc tactttattc tcgatgggga acaaatctta
     1921 gaaagttcat gggattccgt aaatgagtct tatattgcaa cgcttccaac tgtaacatca
     1981 ggaaaaactg ttgttgcttg gcgtgaaaaa ggaactctta atttaattaa accaggaaga
     2041 attgctcggc aatataatag cagtggatca tatgtagaac tttctccaat ctttgaaact
     2101 gctagttggc taaaatcaaa ccaaaactgg tactatcaaa aacaaggtca attagttcaa
     2161 aattcttgga tcaaggatca gggaagctgg tactttatgg atgatgaagg ggttatgttt
     2221 aatcaaacat ggctacacca aggtggaagc tggtatgcct ttaagtcatc aggagccatg
     2281 atttcagctg attggttgta tgataatggt tcttggtatt acctaaagga ctcaggttct
     2341 atggtaacag gatggcttaa aaatggaggc tcttggtatt acctaaacaa gtcaggttca
     2401 atggctacag gttggattaa agatagtgga acttggtatt atctaaagaa ttcaggctct
     2461 atggcgacag gctgggtgaa agatagtggc tcttggtatt atctaaagaa ctcaggttca
     2521 atggcaacag gttgggtcaa agataatggt aagtggtact atctcgcatc atctggtaat
     2581 atgcttcgca atacacgcac accagatggc tattatgtag atggcagtgg cgcttggaaa
     2641 taaattttta aaagagaaaa tctactgaga aggtagattt tctttttagt taatgaatat
     2701 agaataaagt agatcaggac tggtctattt tattttgtaa ctattaatga atagtcttaa
     2761 tgatgaagtt actttctgaa gatatttaat tgtgttgaga tttgataaaa ctatagcgga
     2821 ttgaaataag atataaacaa agagattatg gaagtcaaat taatttctaa aaacgtttta
     2881 aaatccttag cgtactattt tagattcaat ttaatatagt ttaaaaataa gaaaattacg
     2941 taccttattc ttggtgataa aaatgtgaat ttagataaat atatttgat
//
LOCUS       DAVKMJ010000093         2830 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000093 DAVKMJ010000000
VERSION     DAVKMJ010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.093"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..143)
                     /locus_tag="VW348_002112"
     CDS             complement(<1..143)
                     /locus_tag="VW348_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9746943.1"
                     /translation="MNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRLLLAYQQK
                     GKEA"
     gene            348..536
                     /locus_tag="VW348_002113"
     CDS             348..536
                     /locus_tag="VW348_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEU9746944.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            693..1058
                     /locus_tag="VW348_002114"
     CDS             693..1058
                     /locus_tag="VW348_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEU9746945.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            1061..2728
                     /locus_tag="VW348_002115"
     CDS             1061..2728
                     /locus_tag="VW348_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEU9746946.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
BASE COUNT          901 a          516 c          624 g          789 t
ORIGIN      
        1 gcttcttttc ctttctgttg ataggctagt agcagacgat tgatttgtct ttcagaaaga
       61 ttgagttcga cacaggcccg tttctttgtt ttctttcctt gggctatagc ttttatcaca
      121 agatattttt tcgtttcatt catattcagt tggatccttt tcatatgact attctaccaa
      181 atgtgacatt ttcacgttcg atttactaaa gacattatca cattcgaatc acaacacaaa
      241 taaaaaatct tccaattccc ttgcaaaaaa caagaaagtg tgataacata gtacggtatg
      301 tggtgctagc acatccgcta tattagatct aataggagga aaacacaatg gctaaagtat
      361 gttactttac aggtcgtaag actgtatcag gaaacaaccg ttcacacgcg atgaaccaaa
      421 caaaacgtgc cgtaaaacca aaccttcaaa aagttactgt tcttatcgat ggtaaaccta
      481 aaaaagtttg ggcttcagct cgtgctttga aatcaggtaa agttgaacgc gtttaataat
      541 aaaagcaaag gagaccttag ggtctttttt cttttattgt gggtataaca tcgtttgaaa
      601 aatagagtaa atatccgctg atacatcatt ctgcttttac acttgggctg aaatatgata
      661 aaatagagta tcaactagtt gaggtaaaaa ggatgactgt aaaaattaat acaaaagatg
      721 gtcaaatcga actaacagat gaagtgattg caaccgtcgt aggtggagca gcaactgaga
      781 tttttggtgt ggtcggtatg gctagtaaaa atgccctcaa agataatttc caagccctgc
      841 taggtaagga aaattattct aaaggtgtcg tcgtaaaggc agccgaagat ggcagtattg
      901 cagttgatgt atataccgtg ttaagctacg gaacaaagat tagtgaagtg tcaaaaaaca
      961 ttcaagagcg tgttgccttt agcttggaaa accagcttgg aattactgct cagactgtaa
     1021 atgtctacat tcaaaatatc aaagttgtag gagaataacc gtgtcaaaga ttactactag
     1081 cttatttcaa gaaatggtgc aggctgcatc aactcgcttg aataagcaag ctgaatatgt
     1141 caattcatta aacgtctttc cagttccaga tggagatact gggacaaata tgggaatgac
     1201 cattgaaaat ggtgctaaag aagttgcaga caagccagct tctacagttg gagaagtagc
     1261 gagcattctt gccaaagggc ttttgatggg tgcgcgtggg aactcaggag tgattacatc
     1321 tcagcttttc cgtggatttt cccaagctat caaggataaa gacgagttaa caggtcaaga
     1381 cttggctctg gccttccaat caggtgtgga agttgcctat aaggcagtga tgaaacctgt
     1441 tgaaggaacg attttgacag tttctcgtgg agctgctatc ggtgctaaga aaaaagctga
     1501 gcaaacagat gatactgttg aagtcatgcg cgcagccttg gaaggtgcta aaacagctct
     1561 agctaaaaca ccagacatgc ttccagtatt gaaagaagtt ggcgttgtgg actcaggtgg
     1621 tcaaggattg gtcttcatct acgaaggttt cctttcagcc cttactggcg aatatattgc
     1681 atctgaggac tttgtagcga ctcctgccaa catgagtgag atgatcaatg tagagcatca
     1741 taagtctgta gctggtcacg tagcgactga ggacatcacg tttggttact gtactgaaat
     1801 catggtagct cttaagcaag gtccaaccta tgctaaagat tttgactacg atgaattccg
     1861 taactacttg gatgagcttg gggattctct cctcgttgtt aacgatgatg aaattgtcaa
     1921 agtccatgtt catacagaag atccaggact tgttatgcaa gaaggtctca aatatggtag
     1981 cttggtcaag gtaaaagttg acaatatgcg taaccaacac gaagcacagg ttgagaaaga
     2041 agctactcaa gttatcaagt cggctgaaga aaaagagtat gctttgattg ctgtggtggc
     2101 tggtaaaggt ctagcagata tcttctgttc tcaaggcgtg gattatgtta tcgaaggcgg
     2161 tcaaaccatg aacccttcaa cagaagactt tatcaaggct gttgaacagg tcaatgcccg
     2221 taacatcatc ttcttgccaa acaacaagaa catcttcatg gcagctcaat ctgcggcaga
     2281 agttttggag caaccagcag tagtggtaga ggctcgcact cttcctcaag gtatgacaag
     2341 tcttcttgcc tttgatccaa gcaagtccat tgaagaaaac caagagcgta tgacagctgc
     2401 tcttagcgat gtcgttagcg gaagcgtcac aacagccgtg cgtgatacaa cgatcgatgg
     2461 cttagaaatc catgaaaacg ataatctagg tatggtggat ggaaaaattc ttgtgtcaaa
     2521 ccctgatatg caccaaacat tgactgaaac cttgaaacat atgttggatg aagacagtga
     2581 aatcgtaacc ttctatgtcg gtgaagacgg aagcgaagaa cttgccaatg aaatcgctca
     2641 agaaatcgta gaagaattcg aagacgttga agtcgagatt caccaaggtc aacaacctgt
     2701 ttacccatac ctatttagtg tggaataaga ttaatgaagg actgagaaat cagttctttt
     2761 ttctttttta gtaaatgaaa tcggtatctt tttaataaaa acaaaaataa cattcataaa
     2821 taaacgttaa
//
LOCUS       DAVKMJ010000094         2683 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000094 DAVKMJ010000000
VERSION     DAVKMJ010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2683
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.094"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..538)
                     /locus_tag="VW348_002116"
     CDS             complement(<1..538)
                     /locus_tag="VW348_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746947.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRLFSN
                     FDDFLEKNYLKTIWQVSKE"
     gene            complement(552..1265)
                     /locus_tag="VW348_002117"
     CDS             complement(552..1265)
                     /locus_tag="VW348_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEU9746948.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYDLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1725..2105)
                     /locus_tag="VW348_002118"
     CDS             complement(1725..2105)
                     /locus_tag="VW348_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEU9746949.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQTQLAELEINK"
     gene            complement(2522..2674)
                     /locus_tag="VW348_002119"
     CDS             complement(2522..2674)
                     /locus_tag="VW348_002119"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746950.1"
                     /translation="MLEKVTDSSIRQNAVETLTGLKSSLLLGTKDNNTISAEVDSLLA
                     LLKESK"
BASE COUNT          876 a          518 c          404 g          885 t
ORIGIN      
        1 tttctttaga aacttgccat atagtcttta aataattttt ttctaaaaag tcgtcaaaat
       61 tagaaaacaa tcgaaaatac aatgcattct cttggtgtaa aatcgctctt tttaaaggat
      121 aatactcttt aatattatta actttttgtt cgtaggcata ttttgctaca tgatctaggt
      181 atatatcaaa aaagtcatga ggaaaatctc ccatacagcc attacgattc atattgaggc
      241 tatattttcg attagtaaga taattcggaa atatatttcc tattactcta agattatcta
      301 cttgtgaatc ccttctccca atataatccc cttctttgac taatgatgga gatttccaag
      361 taaaaattaa atcgccagag aaatttttct tatcaaaaaa cttaaaaaga gattgataaa
      421 tactatttgc taattgacaa gtgtcagatg taaattcata attaacagct tcattaaaat
      481 caacttcaga catttcaatg tactcttcaa tagtaatatt agcttttttt gtagtcatta
      541 gctaatctcc tttaaaatgt gatcttttca agaatatttt tatctaaaca atccagcaag
      601 tcttggtaag aatagacttc gtaagtcggc tgggcttgtg tgtgattttc gaggtgatga
      661 ggattatacc agatagtgtc aatccccgca ttattgccac cttgaatgtc ggcggttaga
      721 gaatctccaa tcatcagcgt cttttcttta ctaaatccag caatttgctg gccaatcttt
      781 tcataaaaga gagcatccgg cttttgagtt tgcaactgtt ctgagataaa gacttgattg
      841 aaataaggtg ctagaccaga ttgagccaaa cgtcctgtct gaatggcagt aatgccattt
      901 gtcgcagcat acaagtcata atcacgctca atgaggctgt ccaagagatc atgagcgccc
      961 gatagtgttt gtccctgctg ggcgaggtaa aattggtaac gctgggcaag aaaactaccg
     1021 tctttttcct gtccaaaatg agaaaataaa cgagaaaagc gcgtgttaac cagctcttgt
     1081 ttactgattt tcttcagctc caagtctttc cagagagcct tgttcatagg aacgtaataa
     1141 tctttataag cctgaatatc cgcaactcct tcttctttta gaagttgggt caaagccaca
     1201 tcctcagcag catcaaaatc aagaagagtg tggtcgaggt cgaagagtag aaatttgtag
     1261 aacaatttga ggttttcctt tctgaaaatt cattaaaaac attatatcat aaagcacctc
     1321 atacaattaa ctaatttaat cacttaaaaa aaattcgaac actttctata caactgacag
     1381 ctcaaatctt tcagaataga acaatactaa ctatcgagca cccccgtctt cataaatata
     1441 tgtgtaattc tagacctaga attcctataa actaaatgct ttcatactct tccaagtaat
     1501 tgattgcctt aaattttaat ttttgaagga ttctaaagct agaatagccc catcacaatc
     1561 agttttgatt gattcacaat ttagaaacac tatagtttca ctcctgttaa aataaaaagg
     1621 aactgcataa agcaatccct ttctaatttt gaaatcattt acttaacatt ttatagttga
     1681 gataatcaat agcttaccta taaaaagagt tatagtaaaa ttccttattt attgatttca
     1741 agctccgcta actgtgtttg aataactgac agttctgcac cagcctgcag aagagcagct
     1801 gcattatagg caccttctac aattggaacc ctgttgatga tgatactttt atcactgaaa
     1861 tcagtcacca tttttaagtt cattttagca gaacctaggt caaaaaaggc aagtaaagta
     1921 tctgctggat tttcggaaac aaccctatct acttgatcaa aactcgttcc aattcctccg
     1981 ccctcggttc ctcctacata agtaatcgga acatctttag ctactttact aatcagttca
     2041 acaacacctt ctgcaatgtg tttggaatgt gaaacgataa caagaccaat accaatactt
     2101 tccatcaaac caccccagtt tctaaaatag cagtaaagag taatcctgat gagaatgatc
     2161 caggatcaat atgtccaaga aaccatatgc tcctaagaca agagccaaca gactggtcat
     2221 caataatagt attgttcttt ttttcatcat tactccttaa ctagtgttta actgattaat
     2281 tagccagtaa atagtttatc tttatttaca ctatctgtta agatatagta aaataagaac
     2341 aggacagtca aatcgatttc taacaatgtt ttagaagtag aggtatacta ttctagtttc
     2401 aatctactat attttgcaca ttttcatgaa aaaaatgaga actagaactc acattctgct
     2461 ctcatttttc gttttcccgt tctcctatcc tgtttttagg agttagaaaa tgctgctacc
     2521 tttacttact ctcctttaat aaagccaaga gactatctac ttctgctgaa atagtgttat
     2581 tatctttcgt tccgagaaga agactacttt ttagaccagt caatgtctcc acagcatttt
     2641 gtctaatact agaatctgtt actttttcta gcaaggcctc cgc
//
LOCUS       DAVKMJ010000095         2589 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000095 DAVKMJ010000000
VERSION     DAVKMJ010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2589
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.095"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            113..2221
                     /locus_tag="VW348_002120"
     CDS             113..2221
                     /locus_tag="VW348_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="HEU9746951.1"
                     /translation="MKIPMIYQMENSECGLACCAMILNYFKYEISLNELREIYPSSRS
                     GYSLLSISKVLGDFNISSHAFKASVRDLKPLSFPLICFWESSHFIILEKISKNKFYIL
                     DPAKGRQRMSISEFERHYSNIILTFKKLDSFMSRKDNKKSPVLKYFFKYRNKLGILFF
                     VTALLYVIQSLVPIANRYIIDTNFKDDSYSSRMLFTILFIFTVSFSLMYLLRQIYVAS
                     LKYIMDKEISYDFMKHLIYLPYSFYEKRTLGDILFRANSIVYIREILSNNFIAAILDL
                     LMIVVYAVVLFSFSKYMVIFLISLSLALSIVMYPIIKISKNLIDKNIKEKVNVQNITS
                     EVISKNSDIKLTGEEEFWINKWDNFNTKQLIIGRKLDIHLSIVSSITNVLQIILPVLT
                     LIVGVNIKTFEQLTLGQIVAISTVSPYFISPIISLSDNYIQLMLLKGYFLRIEDVFNT
                     KSELIPERVSQDIKFDKKIELKDIWYKYGLFDDYVLKGINVTIKKGETVAIVGESGSG
                     KSTLAKILLGLLEPNIGSIEVDGVEKEEIGQTLYRKIFGAVLQNSTLSYGTLRENLTF
                     GHFVSDEELMTNLNSIGLSNVVKSLPLGLETIIAEEGNNFSGGQQQMILLARCLLSKP
                     SVVVLDEATSSLDNLSQQITTSYLSEIGTTKILIAHRLDTIKSADKILVMHNGEIVEI
                     GTHRELLELGGIYKQLYSNN"
     gene            2245..>2589
                     /locus_tag="VW348_002121"
     CDS             2245..>2589
                     /locus_tag="VW348_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEU9746952.1"
                     /translation="MKIMKKKYWTLAILFFCLFNNSVTAQEIPKNLDGNITHTQTSES
                     FSESDEKQVDYSNKNQEEVDQNKFRIQIDKTELFVTTDKHLEKNCCKLELEPQINNDI
                     VNSESNNLLGEDN"
BASE COUNT          967 a          305 c          413 g          904 t
ORIGIN      
        1 atatttactc gaaaaataat aaatatttag aaaagattaa gtatctaaag aaattagtag
       61 attttagaca agaagaaatt atcgacttta ttttgaacaa ggaggaagta ttgtgaaaat
      121 tccaatgata tatcaaatgg aaaattcaga atgtggatta gcatgctgtg ccatgatatt
      181 gaactatttt aaatatgaga tttctttaaa tgaactacgt gaaatctacc catcatccag
      241 atctggatat tctctcctat ctataagtaa agttttagga gattttaata taagttctca
      301 tgcttttaaa gcttcggtaa gagatttaaa accgctcagt ttcccactca tttgcttctg
      361 ggagagttct cattttatta ttcttgaaaa aattagtaaa aacaagtttt atattttaga
      421 tcctgcaaaa ggcaggcaga gaatgtcaat aagtgaattt gaaaggcatt attcaaatat
      481 cattttaaca tttaaaaagt tagatagctt tatgtctcgt aaagataata agaagtcgcc
      541 tgttttaaag tattttttta agtataggaa taagctaggg attttatttt ttgtaacagc
      601 attattgtat gtaatacaat cattagtacc tatagctaat agatacataa ttgacacgaa
      661 tttcaaggac gattcgtatt cgtctagaat gttatttact atattattta tatttactgt
      721 ttcattctca ctaatgtatt tattaagaca gatatatgtt gcatccttaa aatatataat
      781 ggataaagag attagctatg attttatgaa acatttgata tatttacctt acagttttta
      841 tgaaaaacgt actttagggg atatactttt tagagctaac tctattgttt atataagaga
      901 aatactatca aataatttta tagcagctat acttgatttg ttaatgattg tggtttatgc
      961 tgtggtttta tttagctttt ctaagtacat ggtaatcttt ttaatatcac taagtctagc
     1021 tctatctatt gtaatgtatc caatcataaa aatctcaaaa aatttaattg ataaaaatat
     1081 aaaagaaaag gttaatgttc aaaatattac ttccgaagta atttctaaaa atagtgatat
     1141 taagctaact ggagaagagg aattttggat taacaaatgg gataatttta atacaaaaca
     1201 gctcatcata ggtcgaaaac ttgatataca tttatcaatt gttagtagta taacgaatgt
     1261 tttacaaatt attctccctg ttttgaccct tattgtaggt gtaaatataa aaacattcga
     1321 acaattgacg ttaggacaaa ttgtagcaat aagtacagtc tcaccatact ttatttctcc
     1381 tataatttct ttaagtgata actatataca attaatgtta ttaaagggat attttttaag
     1441 aatagaggat gtgtttaata ctaaatccga attaattcca gaaagagtca gtcaagatat
     1501 aaaatttgat aaaaaaatag aattaaaaga tatttggtat aaatatggat tatttgatga
     1561 ttatgttttg aaaggaataa atgttactat taaaaaagga gaaactgttg ctattgttgg
     1621 agaatcaggt tcaggtaaga gtacattagc taaaatttta ttaggtttat tagaacctaa
     1681 tattggttca atagaagttg atggagtaga aaaagaagaa attggtcaaa cattgtatag
     1741 aaagattttt ggagcagtgt tacaaaattc aaccctaagt tatggtacct taagagagaa
     1801 tttgacattt ggacactttg tttcagatga agaattaatg acaaatctaa attcaattgg
     1861 tcttagcaat gtagttaaat ctttacctct tggattagag acaatcatcg ctgaagaagg
     1921 taataacttt tctggagggc agcagcaaat gatactttta gctcgttgtc ttttgtcgaa
     1981 accttcggta gttgttttgg acgaagcaac aagtagttta gataatttat ctcaacaaat
     2041 tacaacttct tacttaagtg aaatcggtac cactaagatt ttaattgccc atcgactaga
     2101 tactatcaag tctgcagata agatcttagt aatgcataat ggtgaaattg tagagattgg
     2161 gacccataga gaacttcttg aactaggagg catttataag caattgtatt caaataatta
     2221 gtttttgatt aaaagggtaa atttatgaag attatgaaaa aaaaatattg gactttagcg
     2281 atattattct tttgtttgtt caataattct gttactgctc aagaaatacc taaaaatctt
     2341 gatggcaata taactcacac tcagactagc gaaagttttt ctgaatctga tgaaaaacag
     2401 gttgactatt ctaataaaaa tcaagaagaa gtagaccaaa ataaatttcg tattcaaatc
     2461 gataagacag aattatttgt aacaacagat aaacatttag aaaaaaactg ttgtaaattg
     2521 gaacttgaac cacaaataaa taacgatatt gttaactctg aaagtaataa tttactaggc
     2581 gaagataat
//
LOCUS       DAVKMJ010000096         2417 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000096 DAVKMJ010000000
VERSION     DAVKMJ010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2417
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.096"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..282
                     /locus_tag="VW348_002122"
     CDS             <1..282
                     /locus_tag="VW348_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9746953.1"
                     /translation="KEPEKFFGLIEDNLKQVHPLFQTVFKTFLKDKEKIVNALQLHYS
                     NAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(412..1227)
                     /locus_tag="VW348_002123"
     CDS             complement(412..1227)
                     /locus_tag="VW348_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEU9746954.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(1224..2129)
                     /locus_tag="VW348_002124"
     CDS             complement(1224..2129)
                     /locus_tag="VW348_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEU9746955.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
BASE COUNT          802 a          452 c          492 g          671 t
ORIGIN      
        1 aaggaaccgg agaaattttt cggactcatt gaggacaatc ttaagcaggt tcatcctctt
       61 tttcagactg tctttaaaac ctttctaaag gacaaagaga aaatcgtcaa cgcccttcaa
      121 ctacactatt ctaacgccaa attggaagcg accaataatc tcatcaaact tatcaagcgc
      181 aatgcctttg gttttcggaa ctttgaaaac ttcaaaaaac ggatttttat cgccctgaat
      241 atcaaaaaag aaagaacgaa atttgtcctt tctcgagctt agcttttttt caacccacta
      301 cagttgacaa agagccaatc tacaagtcac taattttcat ataacaaaaa aacgaacagg
      361 ctctttttct gttattcaga agagaacttg ttcgttttta tcttgatttt cttaaaaagc
      421 tctatataca tagggatttt ctggtttatc gactttggta aagctgtcga tttccaaggt
      481 tggaaggttt tgtttgagtt ctttatggta gtgattgacc agttttcctt tggctgtaat
      541 ccaggtgttg ttttcatact gccgggtatt gcccttggtc agcaatccat agacaccaga
      601 atctgcgata cagtggataa tgccgaatcg gaacagaaat tgactattgg catgactggg
      661 gtcgttatag acaaagcctg taaactggat tgtcttgccc tcaaattcat ctggatagtc
      721 gtagatagcc tccatgactt ccatatagtt ttcattagtg atctgaatac tatcttggga
      781 taagtattta tccgccgccg ttcgcatttc cttttcatag gctgattttg aaaaataaga
      841 actagtatct ggtttcaaat attggcttgt cgtcccttca cttgtctgaa tagctagatc
      901 cgttccttcc gataggggga aatgataacc tttagcagaa acggtctgag aatccaagct
      961 aacagttggg aaagttaagc cgatgacaag tggaatagcc agaagagaaa tactcgtcat
     1021 cttggccaat cggctgttca gatgactgtg ggttttgact tgcttcatcc agatatacaa
     1081 ttgaacaatt gccaagataa aggaaagcac catggagata taggccagat aggaatagtg
     1141 catgttgatg tactggttta gtttgcccga cagatggagg taaatagtca gttcaaaata
     1201 gccagctaaa actaaaaatc gaatcatagg atgactccaa tcaagagaga ataggctaaa
     1261 acgaccagag tcacaatcgt aatgaagtga ctaataaatc gtgctttcaa gtaatttttc
     1321 atcatgagaa tatttttgat atccagcatt gggccaatga cgagaaaggc cagaactggt
     1381 gccaaaccga aactcgagag tagagaagca cctataaagg catccgcctc actacagagc
     1441 gaaagaagaa aggctaaaag catcaagagc aggatagcaa aaagaggagt cgcactgata
     1501 gaggtcagaa tccgagtcgg aacgtagacc tgtattatag aagcaaagag gcagccaaat
     1561 accaaataac gccccgtatc aaaaaattca tcaatggcct gcacaaagac ttgaaaaact
     1621 ttttttgcag aactcaagta agaaaaatca tgctcatgac aagccagacg attttctttc
     1681 tgaatcggtt cttgccagaa aaatcctaga aaaattccta gtattacagc cacaagaatg
     1741 gaacccagag ctcgtaatag ggcgacatgg aaggagttgc caaaggcaga ataggtcgca
     1801 aaaagaacaa tgggattgat aacaggtgct gtcacaagaa aaggaacggc cgtgtaactt
     1861 ggaacctttt tttccagaaa acgattgatg atggggacga ttccacattc acaagaaggg
     1921 aaaagtatac cgacaaaggt cccaaaaaag attctccccc aacgatttcg agggagaaaa
     1981 tgataaacct tgtcaggtgt gatataaact tcaatcagcc ctgagacaat gcttcctatc
     2041 agaacgaagg gaagggcttc aatgataatg gagagaaaaa tggctccagt ttgaagtaca
     2101 ctagatggga gttgttgaaa agcagtcatc tagtttttct tttctgcttt gacttttttc
     2161 tctttgtcat cagggaaagt aacttgtttc aaatcaggga gtttagcaaa ctcttcaaac
     2221 atcttgtcca agtcgtctcg ttttgtaaat ttgacagcca taggtgtacc tcgattctaa
     2281 attctacctc tattatacta ttattttgcg gaaaagggaa aagttaaaat ttcaaattga
     2341 gtagctaaga gataatatag cttgatatta cctgatatat atcataattg tgctataatt
     2401 aaataaaaag aaaatca
//
LOCUS       DAVKMJ010000097         2133 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000097 DAVKMJ010000000
VERSION     DAVKMJ010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2133
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.097"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            40..491
                     /locus_tag="VW348_002125"
                     /pseudo
     CDS             40..491
                     /locus_tag="VW348_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            656..955
                     /locus_tag="VW348_002126"
     CDS             656..955
                     /locus_tag="VW348_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEU9746956.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            complement(1064..2133)
                     /locus_tag="VW348_002127"
                     /pseudo
     CDS             complement(1064..2133)
                     /locus_tag="VW348_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          660 a          416 c          368 g          689 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagt gaatacagac tatattactc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gaaaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact cctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tcaaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattggcta atactcttcg aaaataaaat tcaaatcacg taagcgtcgc cttaccgtac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgttataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcaactag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag acctctgttg atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataaca aaacgcatag
     1021 tagcaagagt tttgtactga ccccaaaaag ttagacaaat aatttatccg aaggatttag
     1081 ttctgtattg cacaaggcta agtcctttta gttttacctt aattcgttta ttgttgtagt
     1141 aatcaatata gtctacaata gcttgttcca attgattaag tgatttaaat gttttctcat
     1201 agccataaaa catttccgat ttcagaatcc caaagaagga ctccatcata ccgttgtctt
     1261 ggctgtttcc cttacgtgac atggatgctt gaattccctt accctcaaga aactgatgat
     1321 aagaatcgtg ttgatattgc cagccttggt cactatggag aatcgtattc tcgtagtgct
     1381 tctctgtgaa tgcctgttcc aacattgttt gtacttgttc taagttgggt gaagttgaaa
     1441 gattataggc gataatttcg ctattaaagc catctaaaac tggtgataag taaagctttt
     1501 gagtacttgc tggaatggca aattctgtca catctgtata gcactttccc attgttttag
     1561 agccttcaaa ttggccttga atgagattct ctgccttctt gccaacgtct cctttatgag
     1621 aagaatattt tcgtttctgt cgcattttag cttgtaaatt gagtactttc atcaagcctt
     1681 gaactctttt atgatttacc agataaccac gatttcttag ttctaaataa atccgacgat
     1741 aagcataatt tcccttgtgt tcgataaaaa tggattgaat ttcagcttta agctcttggt
     1801 ccttatctgt tttgtctagc tgtttcaagt gatagtagta ggtcgaacga gctagtttaa
     1861 tggattttag aagaagaact aacgaaaact cagtcattaa ttcttgaaca atttctgtct
     1921 ttcttctttc tctttttcct ccttcaatcg gagttctctt aactttttta ggatggcatt
     1981 ctccgctctc aggtactctc ccttttgttt tctcaacaat agtatacccg tttttcctgt
     2041 attgtgctag ccagttaaga agtatcgtac gacttgggag gccgtattca agagaaactc
     2101 tatctttagt ccagccttca tgtcagactt tat
//
LOCUS       DAVKMJ010000098         2088 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000098 DAVKMJ010000000
VERSION     DAVKMJ010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2088
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.098"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            54..169
                     /gene="rrf"
                     /locus_tag="VW348_002128"
     rRNA            54..169
                     /gene="rrf"
                     /locus_tag="VW348_002128"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            174..246
                     /locus_tag="VW348_002129"
     tRNA            174..246
                     /locus_tag="VW348_002129"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:207..209,aa:Val,seq:tac)
     gene            249..321
                     /locus_tag="VW348_002130"
     tRNA            249..321
                     /locus_tag="VW348_002130"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:282..284,aa:Asp,seq:gtc)
     gene            346..418
                     /locus_tag="VW348_002131"
     tRNA            346..418
                     /locus_tag="VW348_002131"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:379..381,aa:Lys,seq:ttt)
     gene            424..505
                     /locus_tag="VW348_002132"
     tRNA            424..505
                     /locus_tag="VW348_002132"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:458..460,aa:Leu,seq:tag)
     gene            524..596
                     /locus_tag="VW348_002133"
     tRNA            524..596
                     /locus_tag="VW348_002133"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:557..559,aa:Thr,seq:tgt)
     gene            619..690
                     /locus_tag="VW348_002134"
     tRNA            619..690
                     /locus_tag="VW348_002134"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:651..653,aa:Gly,seq:gcc)
     gene            698..783
                     /locus_tag="VW348_002135"
     tRNA            698..783
                     /locus_tag="VW348_002135"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:732..734,aa:Leu,seq:taa)
     gene            793..866
                     /locus_tag="VW348_002136"
     tRNA            793..866
                     /locus_tag="VW348_002136"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:827..829,aa:Arg,seq:acg)
     gene            882..955
                     /locus_tag="VW348_002137"
     tRNA            882..955
                     /locus_tag="VW348_002137"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:916..918,aa:Pro,seq:tgg)
     gene            961..1034
                     /locus_tag="VW348_002138"
     tRNA            961..1034
                     /locus_tag="VW348_002138"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:995..997,aa:Met,seq:cat)
     gene            1048..1121
                     /locus_tag="VW348_002139"
     tRNA            1048..1121
                     /locus_tag="VW348_002139"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1082..1084,aa:Ile,seq:cat)
     gene            1132..1221
                     /locus_tag="VW348_002140"
     tRNA            1132..1221
                     /locus_tag="VW348_002140"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1168..1170,aa:Ser,seq:tga)
     gene            1232..1305
                     /locus_tag="VW348_002141"
     tRNA            1232..1305
                     /locus_tag="VW348_002141"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1266..1268,aa:Met,seq:cat)
     gene            1309..1381
                     /locus_tag="VW348_002142"
     tRNA            1309..1381
                     /locus_tag="VW348_002142"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1342..1344,aa:Phe,seq:gaa)
     gene            1401..1471
                     /locus_tag="VW348_002143"
     tRNA            1401..1471
                     /locus_tag="VW348_002143"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1433..1435,aa:Gly,seq:tcc)
     gene            1507..1580
                     /locus_tag="VW348_002144"
     tRNA            1507..1580
                     /locus_tag="VW348_002144"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1541..1543,aa:Ile,seq:gat)
     gene            1587..1674
                     /locus_tag="VW348_002145"
     tRNA            1587..1674
                     /locus_tag="VW348_002145"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1621..1623,aa:Ser,seq:gct)
     gene            complement(1807..>2088)
                     /locus_tag="VW348_002146"
     CDS             complement(1807..>2088)
                     /locus_tag="VW348_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEU9746957.1"
                     /translation="KEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYS
                     NAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT          497 a          431 c          556 g          604 t
ORIGIN      
        1 attgttttct tggtttgaat agatattcaa ttttgagtag gtattactca gagttaagtg
       61 acgatagcct aggagataca cctgtaccca tgccgaacac agaagttaag ccctagaacg
      121 ccggaagtag ttgggggttg ccccctgtga gatagggaag tcgcttagct ctagggagtt
      181 tagctcagct gggagagcat ctgccttaca agcagagggt cagcggttcg atcccgttaa
      241 ctcccaaagg tcccgtagtg tagcggttat cacgtcgccc tgtcacggcg aagatcgcgg
      301 gttcgattcc cgtcgggacc gtttaaggta acgcaagtta ttttagactc gttagctcag
      361 ttggtagagc aattgacttt taatcaatgg gtcactggtt cgagcccagt acgggtcata
      421 tatgcgggtt tggcggaatt ggcagacgca ccagatttag gatctggcgc ttaacggcgt
      481 gggggttcaa gtcccttaac ccgcattaag atataacaaa tgagccggct tagctcagtt
      541 ggtagagcat ctgatttgta atcagagggt cgcgtgttca agtcatgtag ccggcatttt
      601 tagatagaag aaaacagtgc gaacgtagtt cagtggtaga acaccacctt gccaaggtgg
      661 gggtcgcggg ttcgaatccc gtcgttcgct tagagaggcc ggggtggcgg aactggcaga
      721 cgcacaggac ttaaaatcct gcgattggta acgatcgtac cggttcgatt ccggtcctcg
      781 gcataatatg gagcaccctt agctcaactg gatagagtac ctgactacga atcaggcggt
      841 tagaggttcg actcctctag ggtgcatttt tctatttaac tcgggaagta gctcagcttg
      901 gtagagtact tggtttggga ccaaggtgtc gcaggttcga atcctgtctt cccgattcat
      961 ggcggtgtag ctcagctggc tagagcgtcc ggttcatacc cgggaggtcg ggggttcgat
     1021 ccccttcgcc gctataatga tcttgtcgga cctttagctc agctggttag agctctcggc
     1081 tcataaccga gtggtcgtag gttcaagtcc tacaaggtcc atttgaatat tggaggatta
     1141 cccaagtccg gctgaaggga acggtcttga aaaccgtcag gcgtgtaaaa gcgtgcgtgg
     1201 gttcgaatcc cacatcctcc ttttatatta acgcgggatg gagcagctcg gtagctcgtc
     1261 gggctcataa cccgaaggtc gtaggttcaa atcctgctcc cgcaataagg ctcggtagct
     1321 cagttggtag agcaatggat tgaagctcca tgtgtcggcg gttcgattcc gtctcgcgcc
     1381 attttattga tagtatttat gcgggtgtag tttagtggta aaactacagc cttccaagct
     1441 gttgtcgcga gttcgattct cgtcacccgc tttgaacttt gttcaaatta ccaagttttt
     1501 taacttgggc gcgtagctca ggtggttaga gcgcacgcct gataagcgtg aggtcggtgg
     1561 ttcgagtcca ctcgtgccca ttaattggag aattactcaa gaggctgaag aggacggttt
     1621 gctaaatcgt taggtcgggt aactggcgca agggttcgaa tcccttattc tccgttttaa
     1681 tgagagtttg taactctctt ttttattttt agagacaata aagcttcaga tccgtaaaac
     1741 ttaattgaat tactaatctg aagttatttt taggctcttt gtcaactgta gtgggttgaa
     1801 aaaaagctaa gctcgagaaa ggacaaattt tgtcctttct tttttgatgt tcaaagcgat
     1861 aaaaatcctt tttttgaagt tttcaaagtt ccgaaatcca aaggcgtttc gtttgataag
     1921 tttgatgaga ttatttgtcg cttccagttt ggcgttagaa tagtgtagtt gaagggcgtt
     1981 gacaatcttt tctttatctt tgaggaaggt tttaaagaca gtctgaaaaa taggatgaac
     2041 ctgcttcaga ttgtcctcaa taagcccgaa aaatttctct ggttcctt
//
LOCUS       DAVKMJ010000099         1920 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000099 DAVKMJ010000000
VERSION     DAVKMJ010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1920
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.099"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            19..606
                     /locus_tag="VW348_002147"
     CDS             19..606
                     /locus_tag="VW348_002147"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746958.1"
                     /translation="MYNQDTREAKAKFYSEQLLSKISGVEPKITSDMQRIAGENKLAG
                     LEFRKKTVESLSRKITTDSQAENISLSKATSKINDALRYTTIFDPDTFAKEYLKMKQK
                     LIAEGYKIVKVKNTWLVDGPYKGVNTVVEKDGINFEMQYHTQESFDLKNGSLHELYEK
                     YRDTNTSDLERMKLFKEMLDLSNGLEIPKNIERVK"
     gene            608..817
                     /locus_tag="VW348_002148"
     CDS             608..817
                     /locus_tag="VW348_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746959.1"
                     /translation="MKDIKYYRTTTNNAQVLRLIDGVMQVFDIEKKWVNSMDWFNKIF
                     FNDFTDFEEISENDAFTYIDRMVAA"
     gene            814..1227
                     /locus_tag="VW348_002149"
     CDS             814..1227
                     /locus_tag="VW348_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEU9746960.1"
                     /translation="MIDIALAIAKKAHAGQVDKAGVDYIQHPLYVASQVNTEQEKAVA
                     LLHDVIEDSDITAADLFASGLSNEVVTAVQILTKKKGQSYQEYLGKVKSNNLARVVKL
                     ADLKHNSDLSRLKSVTNTDYERVKKYKNAIHYLST"
     gene            1270..1515
                     /locus_tag="VW348_002150"
     CDS             1270..1515
                     /locus_tag="VW348_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746961.1"
                     /translation="MKYRKKPVVVEAVQWNGNNHKEVIDFAENKIWFDALGNIWIATL
                     EGDMVAKKGDYIIKGVQGEYYPCKLDIFAETYEKTEE"
     gene            1517..1768
                     /locus_tag="VW348_002151"
     CDS             1517..1768
                     /locus_tag="VW348_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746962.1"
                     /translation="MLEKAKQLASQEFSRLSGREIKAEDCFVVWFSKTLQNWKALVST
                     NAITSSEPCGNYAEITHNGDKKETYVDVYAKVSNRAIKD"
BASE COUNT          702 a          288 c          411 g          519 t
ORIGIN      
        1 gcgaaagacg gggaaaaggt gtataatcaa gatacaagag aagccaaggc gaaattttat
       61 agcgaacaac tattgtccaa aatttcagga gttgagccaa aaattacaag tgatatgcaa
      121 cgtatcgcag gagaaaacaa attggcaggt cttgaattta ggaagaaaac agttgagtca
      181 ttatcacgta aaattacaac agatagccaa gctgaaaata taagtttatc aaaggctaca
      241 agtaaaatta acgatgcttt gcggtataca actattttcg atcccgatac tttcgcaaaa
      301 gagtatttga agatgaaaca gaagcttatc gcagaaggtt ataaaattgt aaaagtaaaa
      361 aacacttggc tagtagatgg accatacaaa ggtgtgaata cagtcgttga aaaagatggt
      421 atcaactttg aaatgcagta tcatactcag gaaagtttcg acttaaaaaa tggttcatta
      481 catgaactct atgagaagta tcgtgatacg aatacatctg atctagaacg catgaaatta
      541 tttaaggaaa tgcttgattt aagcaatggg cttgagattc ctaaaaatat agagagggtg
      601 aagtgatatg aaagatatta aatactaccg cacaacgacg aacaatgctc aagtacttcg
      661 tttgattgat ggtgtcatgc aagtttttga cattgaaaaa aagtgggtta atagcatgga
      721 ttggtttaat aaaatctttt ttaatgactt tacggatttt gaagaaattt cagaaaatga
      781 tgcatttact tatattgaca ggatggtagc ggcatgattg atattgcctt ggctatcgct
      841 aaaaaagcac atgcagggca ggtagataaa gcgggtgttg attacataca gcatcctctc
      901 tatgtggcca gtcaagtcaa cactgaacaa gaaaaagctg tcgctctttt acatgatgtg
      961 attgaggata gcgatataac tgctgccgat ttattcgcgt ctggcttgtc aaatgaagtt
     1021 gttacagcgg tacaaatttt gacaaagaaa aaaggtcaaa gttatcaaga atatcttggg
     1081 aaagtaaaat caaataattt agcaagagtt gtaaaacttg cagatttgaa acataactca
     1141 gatttatcac gtttgaaatc tgttaccaat acagactacg agcgtgttaa aaaatataaa
     1201 aatgcaattc actacttaag cacctagaga gatctaagtg cttttttcgt acccagaaag
     1261 gagtgaggaa tgaaataccg taaaaaacca gtagtggtcg aggctgtgca gtggaacggc
     1321 aataaccata aagaggtaat tgactttgca gaaaataaga tttggtttga tgcacttggg
     1381 aatatatgga ttgctacact tgaaggtgat atggtagcta aaaaagggga ttatattatc
     1441 aaaggcgtgc aaggagaata ttatccatgc aagctggata tttttgcaga aacatatgaa
     1501 aaaacggagg aataaaatgt tagaaaaagc aaaacaattg gcatcgcaag aattttcacg
     1561 cttatcaggt cgtgaaatca aagcagaaga ctgctttgta gtttggttta gcaagaccct
     1621 gcaaaactgg aaagctcttg ttagtacgaa cgcaattaca tcaagcgaac cttgtggaaa
     1681 ttatgcagaa atcacgcata acggagataa gaaagagact tatgtggatg tttacgccaa
     1741 agtttcaaat cgtgccatta aagattagga ggtgatccaa catcttgact tgcaggaata
     1801 gactgctata aattgctata aaccgcatcg aaatcgaggc ggttttctta tgccctaacc
     1861 gtatggaacc ccgtacggtt tttatattgt ccaaactgta ccgatgacat taaaagctgt
//
LOCUS       DAVKMJ010000100         1854 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000100 DAVKMJ010000000
VERSION     DAVKMJ010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1854
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.100"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            80..>1854
                     /locus_tag="VW348_002152"
     CDS             80..>1854
                     /locus_tag="VW348_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4365 domain-containing protein"
                     /protein_id="HEU9746963.1"
                     /translation="MANNRKTETLGVSYLSTFIDKHELLQSYFESNDKTPVWDGEIHV
                     LKSPSEKKDEILGKVPVQIKTTRQKKDVLKSFSLDTRDLELYKPNGGVVLFVVWLNED
                     NGLRDIYYKSLPPLSIKNLLKKSKLKNKSTNRKKLSIEIFKLDEKKMYPMLVDFINNS
                     QKQYSFINVEGISVEDIPDDKTLKFYFYGQEKEEIFNYQEEHDLFIYYLDPITGIEIP
                     LENTIKIVETEEETDLIIKIGDYVFQDVKRHRFPDGSVQLHFGESFTMSFDIKKKQFK
                     FNYTRPDLLSKAIKCTQVFQELGKIGYFTLNGNKIELDERSIKDISSLDLEADIKGLL
                     KISNFMKKMGIQKDVDLSCFDKQSQRNLNILYSGLVLKKKVALNYNESKLLHLNIANI
                     HIITLYSFLSDKNGTMIDIFTETPWCREGETEDEDYLDISIFEVFEPNDWLKIDNCKI
                     DSVIASYQRLVDNKLKYEGADRTILKIVIAADMAEDKTKRELLLNWAQCLSDWNLKYS
                     KNCEMAIINDLQIKSRVRKLNSKETETLTNILVNSNDNYELCFGSSVLLKSKPQADLF
                     WNKLDNETKERYKDFPIYTLYMKLS"
BASE COUNT          709 a          224 c          319 g          602 t
ORIGIN      
        1 gtagtttatt gaatgctatg tatttttatt tcttaatgct ataatataaa gtatatagag
       61 ttattttaga ggtgcagatt tggccaataa taggaaaact gagacattag gtgtttcata
      121 tctttcaaca tttatagata agcatgagtt acttcaatct tattttgaaa gtaatgataa
      181 aactccagta tgggatggag aaattcatgt tcttaaatca ccgagtgaga agaaagacga
      241 aatattaggt aaagtacctg ttcagattaa aactactaga cagaaaaaag atgtgttaaa
      301 atccttctca ttagatacta gagatttaga actatataaa ccaaatggtg gagtagtttt
      361 atttgtagtt tggttgaatg aggataatgg tttaagagat atttactata agtcattacc
      421 tcctctttct ataaagaatt tgctcaaaaa gagtaaacta aaaaataaat ctacaaatag
      481 gaagaaactt tccatagaga tttttaaact ggatgagaaa aaaatgtatc caatgttagt
      541 ggatttcata aacaatagtc agaagcagta tagtttcata aatgtcgaag gtatttcagt
      601 tgaggacatt cctgatgata aaactctaaa gttctacttc tatggtcagg aaaaagaaga
      661 aatttttaac tatcaggaag aacatgatct ctttatttat tatttagatc ctataactgg
      721 catagaaata cctcttgaaa acacaataaa gattgtagaa actgaagaag aaacggattt
      781 aattataaaa ataggcgatt atgtttttca agacgtaaaa agacatcgtt ttcctgatgg
      841 gagtgtacag cttcattttg gtgaaagctt tacaatgtct tttgacataa agaagaaaca
      901 attcaaattt aactatacta ggccggattt gctgtcaaaa gctataaagt gtactcaggt
      961 atttcaagag ctaggaaaaa tcggatattt tacccttaat ggtaataaaa tagagttaga
     1021 tgaacggtca ataaaggata tttcttcact tgatttagag gctgatataa agggattgtt
     1081 aaaaatttct aactttatga aaaaaatggg tatacaaaaa gatgttgatt tatcttgctt
     1141 tgataaacaa tctcaaagaa atctaaatat tctttattca ggtcttgtct taaaaaagaa
     1201 agttgcttta aattataatg aatcgaaatt acttcaccta aatattgcta acatccacat
     1261 tataacttta tatagttttt tgtcagataa aaatggaact atgatagaca tttttactga
     1321 aactccttgg tgccgggaag gagaaactga agatgaagat tatttagaca tttcaatttt
     1381 tgaagtattt gaaccaaacg attggctaaa aattgataat tgtaaaattg attcagttat
     1441 tgcctcgtat caaagattgg tagataataa gctgaaatat gaaggcgctg accgtactat
     1501 tttaaaaata gttatcgctg cagacatggc agaagataag actaaaagag agttgttact
     1561 taattgggcg caatgtcttt ctgactggaa cttaaaatac tcaaaaaatt gtgagatggc
     1621 tataataaat gaccttcaaa taaaatctag agttcgtaaa ttaaacagca aagaaacaga
     1681 gacactaact aatattttag taaatagtaa tgataactat gaactttgtt tcggttcatc
     1741 agtgctatta aaatcgaaac cacaagctga tttgttttgg aataaactgg ataatgagac
     1801 aaaagaaaga tataaggact ttcctattta tactttgtat atgaaattat cgta
//
LOCUS       DAVKMJ010000101         1778 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000101 DAVKMJ010000000
VERSION     DAVKMJ010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1778
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.101"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(615..1595)
                     /locus_tag="VW348_002153"
     CDS             complement(615..1595)
                     /locus_tag="VW348_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HEU9746964.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDDFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKKGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAVEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
BASE COUNT          556 a          371 c          332 g          519 t
ORIGIN      
        1 tttcaaaaaa ttcttttata taataatgtc cttgaaagta gtttcagctg aacatttata
       61 gtccataaaa agaaaacaga aactcatctg tttttatact caatgaaaat caaagagcaa
      121 actaagaagc tagccgcatg atgctcaaaa cactgttttg aggttgtaga taagactgac
      181 aaagtcagct caaaacaccg ttttgaggtg gcagatagaa ctgacgaagt cagtaacata
      241 tatacggcaa ggcgaagctg acgtggtttg aagagatttt tgaaaagtat taacacctac
      301 agacaagcct aacgatagca agaactaccc tactcgatag gtatcggctt ttgctttctg
      361 aaaaaaatta ttttaagcaa tttgacaaat ctagcaacaa aaaattctat aaatataata
      421 gattgaaact agaatagtac acatctactt ctaaaacatt gttagaaatc gatttgactc
      481 tcctgatcga tttgtcctgt tcttgtttca ttttactata tttccatgat aaaacgcata
      541 gtatcaagtt ttcttaatcc cctgatacta tgcgtgtttg taatttttaa gattttgtgc
      601 ttagagtcga ctccttattt tagatattta aaaggaatct cacttccaca gagccagttg
      661 tagacttggt cattgacaaa tacattcatg gcttcgtgag catactcagg catgatgcga
      721 taggttttat cgcaggtcag acgattataa atcgcaaact gggtaatggg atagcaaaca
      781 tcgtcgtcca agcccgtaat catcttaacc tcaccttgga tacgatgggc aagatttttg
      841 acatcgatat aggcaagggt cgccatgatt tcctcctctg tttcatggaa ggggtcgtga
      901 aacttgaaat aacggaaaag ttcgtcgtaa gcctcgctag tattaccaat ctcaatcacc
      961 cgtctgaagt ctgacaagaa gggataaatg gcaactgttt tctgaattcg aggattgagc
     1021 gctgctgcaa ctagagctag agcccctcct tgtgaggcac catagctaga aagacgcttc
     1081 tcatcaacct gagacagact agcaacaatt tcgaccaact ggtaaatatc cagataaaca
     1141 tccttataaa agaggtggtc ccgaccttcc acagcaccac ggataatatg ccccttcacg
     1201 gtatttccta aaggagaacg caagccgtct tgtgagtaac ctgactggcc ccgcacatcc
     1261 atggaaacaa caccgtaacc agctacggtg aagcccagca tgtcggccca gtcccagcca
     1321 cgtcccatat aaccatgaaa atggaagatt agtggaacct tctcctcact ctttggaaga
     1381 acaatgcgtg catagacctt tcctttcttg cttccttcaa atgttaactc atagcacttg
     1441 acttgaggaa tgtggaaatc tctttcctcc aagtggtagg atggaagcgt ggaaacattt
     1501 ttcacttccc catcccagaa atcatcaaag tcttccggaa cctcatccct tcctctatag
     1561 gtcttaattt cttctagcaa agctggattt ttcatagcat gctcctttta ttttgtaatc
     1621 gttaccacaa ctgtagcata tctatgtaat caatgcaaga aagaagggta aatagaaagt
     1681 gaatttagat tctttacttt taggatgatg ggctgaaagt agttttagaa acgaaaaaag
     1741 agcatttcgc tctctcttct gtttatacta gttttttg
//
LOCUS       DAVKMJ010000102         1546 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000102 DAVKMJ010000000
VERSION     DAVKMJ010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1546
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.102"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            27..939
                     /locus_tag="VW348_002154"
                     /pseudo
     CDS             27..939
                     /locus_tag="VW348_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(972..1312)
                     /gene="tnpB"
                     /locus_tag="VW348_002155"
                     /pseudo
     CDS             complement(972..1312)
                     /gene="tnpB"
                     /locus_tag="VW348_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
BASE COUNT          487 a          277 c          321 g          461 t
ORIGIN      
        1 gtgtactgtt atagattcaa tacactataa actgtaatca aacaacgatt tggcgaaatg
       61 taaaaaaata tgaggagttc ggactcgact ctctccttca agaaacacgt ggtggtcgta
      121 accatgcata tatgacggtt gaggaagaga aagcctttct tgcccgtcat ttgaaggctg
      181 cagaggcagg agaatttgtt acaattgatg ccttatttca ggcttataaa aaggagttag
      241 gtcgttccta cacacgtgat gccttctatc aactgttgaa gcgccatggt tggcgaaata
      301 ttatgccacg tccagaacat cctaagaaag cagacgctca aaccattgtc gcgtctaaaa
      361 ataaaatctc aattcaagaa gaaaagaaag cgctttaaaa ccagtagacg ttttcataag
      421 gtttgcttga tgtaccaaga tgaggctggt ttcggtagaa tcagtaaact gggatcttgt
      481 tggtctccaa taggagtagg tctacatgtc catagtcact atatacgaga atttcgctat
      541 tgttatggag ctgttgatgc ctatacaggc gaatcatttt tcttaatagc tggtggatgt
      601 aatactgagt ggatgaacgc ctttttagaa gagctttcac aagcttatcc agatgattat
      661 cttttactcg ttatggacaa tgctgtatgg cataaatcaa gtaccttaaa gattccgact
      721 aatattggct ttgcatttat tcctccatac acaccagaga tgaaccccat tgaacaattg
      781 ttgaaagaga ttcgtaaacg tggatttaag aataaagcct ttcgaacttt ggaagatgtc
      841 atgaatcaac tccaagatgt tatacaagga ctggagaagg aggtgataaa gtccatcgtt
      901 aatcggagat ggaatagaat gctttttgaa agcagatgag tataaaaaga aagtcctcat
      961 ttcaatagaa atcacgactt tctgatggat ttatttttgg agtgatagaa aagcccgtca
     1021 taagccagtc tacttgttca ggtgtgagag ctttgacatc cttttctgta ttgggccaag
     1081 tcagtctgcc gttctcaaag cgtttatata gtagccaaaa tccttgacca tcccagtaaa
     1141 gggctttaaa gcggtcttta cgtccaccac aaaagagaaa gacttgaccg gagaaaggat
     1201 ccaattcaaa gtgggtttta actacatagg ctaatgagtc tattccctgc ctcatatcta
     1261 tcttgctaca aacaaggtga acttgaccta aatcacttag ttgaattatc atagtacaat
     1321 acctttcctc cgataattat tttttatcta gtatactgga agttggggaa ttaggataga
     1381 taccttgtta tgacgcgctt acgtaacttg taactagctg cctagtttga tctttgcttc
     1441 ttcattgatt agcagtagat ttcaaaatga taaaaacgca taatagtggg tgtagaatga
     1501 actgccttcc aaaaagttag acagaaaaaa tctaactttt ggggtg
//
LOCUS       DAVKMJ010000103         1539 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000103 DAVKMJ010000000
VERSION     DAVKMJ010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1539
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.103"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(525..1517)
                     /locus_tag="VW348_002156"
     CDS             complement(525..1517)
                     /locus_tag="VW348_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEU9746965.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
BASE COUNT          527 a          261 c          192 g          559 t
ORIGIN      
        1 atagtggatt tacccactac aaatattata gaacccaaaa atgctctgaa acactgattt
       61 caaggcattt tttgttagtt taaaattact cccattcttc ttttccaaac atacaatata
      121 tccaaaacca ttcaaaatac tagattctat tttttataat atcactaaat ccacctaatt
      181 ataggacgtt ttcagatttt tagtcccgtc ccagtcccag taccggagaa atattgtttt
      241 aatataatat ctctttttgt cttctaagct cttaaaagca aaagaacaag taaagagtca
      301 agacaaggat aaaaagtcca tattagggca aataaaaagc tttaagacag atgacaaatc
      361 taagtcaaat aagaaagacc atagcaaagg tgcagagaga taaatattgg cggtcttcgg
      421 actgccttta tttttttatc catttttcaa atcaaattta ttcagactat atatgcacat
      481 atacacttaa attcatataa aaacatggct tgtaaaaaat tactttaatc acaataatcg
      541 catttaaaat tgtgatgttt gcaagctaaa ttacggactt cacttggaag ttttcccttg
      601 tatcttttat aatagataga aaatttgctg gcagatgaat atccaacaga ttctgctatc
      661 tcttttatag gtagttcagt gtttaaaaga agagtttcag ctacattcat tctttttctt
      721 tgagtgtact ctgtaatgct ttgacaatat ttttccttaa ataaattttt taatttagta
      781 ccactcattt tagatatttt ttcaagcgtg ccttgattta cattcgttgc aaaatgatca
      841 tctaagaatc ttgctacatc ttcaagtgct ttatcatcat caatttcaat tttatatttt
      901 tttctattta agtatgtgtc aattactata cttatccatt catttgcctt tgctttaaag
      961 aaaaaatcag cggcaggagc gtccatctta caatttaata tttccattgc cactctttct
     1021 aaggcctttg taagtattat ttgattcggt tgaagcaagg ttgaataaaa agattctgga
     1081 ttaatgttaa tagatgctaa atgtttttct attagctctt ttttaaaacc aatggaaaca
     1141 gcaagataac aacaattctc gtgtaataaa aaaacaaaat catcttttat attatcaaaa
     1201 tcaaaagtac ataaagagtt tgcggtaata gtttgatacg gattaaactt ttctccgttt
     1261 gcactgacaa tgtaacttga ataaattgaa acatagtctg acatactata agtgctattt
     1321 tgaactactt cctctttgat ataaaaatca tgtatatcga taatgaagct gcctccttca
     1381 taaaaccaat ataggccttc tgcataagtt gaattctctt ttttccaaca aaatgtatga
     1441 cctgcacttg aatacttctc attgttttta cattcatcta ctttcatata atcttttaca
     1501 aaatcataat atgacataac acactatccc ttttagaca
//
LOCUS       DAVKMJ010000104         1519 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000104 DAVKMJ010000000
VERSION     DAVKMJ010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1519
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.104"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            45..392
                     /locus_tag="VW348_002157"
     CDS             45..392
                     /locus_tag="VW348_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEU9746966.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEIEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(509..1468)
                     /locus_tag="VW348_002158"
                     /pseudo
     CDS             complement(509..1468)
                     /locus_tag="VW348_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          455 a          292 c          281 g          491 t
ORIGIN      
        1 tttaaaagat cggagcaatc cggtcttttt atggaggaga gtaaatgaat ttaaatcaat
       61 tagatattat cgtttcaaat gttccccaag tctgtgctga cttggagcat atcttggata
      121 aaaaggcaga ttatgctgat gatggttttg ctcagtttac gattggtagt cactgcctta
      181 tgttgtcaca aaatcatttg gttcctttgg aaaactttca gtcaggaatc attattcata
      241 tcgagattga ggatgtagac cagaactaca aacggttgaa cgagcttggt ataaaggttt
      301 tacacggacc aactgtaacc gattggggaa cagagtcctt attagttcaa ggacctgctg
      361 gtctagtgct tgatttttat cgtatgaaat aggtcgcgta gtcatttgac gttaacctta
      421 gctattttta aaatagaaat tgagaatatg aactattgaa agatcggagc aatccggtct
      481 ttttatataa agaaattgca tataatactc atctgctttc aaaaagcatt ctagtccatc
      541 tccgattaac gatggacttt atcacctcct tctccaatcc ttgtatgaca tcttggagtt
      601 gattcatgac atcttccaaa gttcgaaagg ctttattctt aaatccacgt ttacgaatct
      661 ctttccacac ttgttcaatg gggttcatct ctggtgtgta tggaggaata aatgcaaagc
      721 caatattagt cggaatcttt aaggtacttg atttatgcca tatagcattg tccataacga
      781 gtaaaaaata atcatatgga taagcttgtg aaagctcttc taaaaagacg ttcatccact
      841 cagtattaca tccaccagct cttaagaaaa atgattcgcc tgtataggca tcaacagctc
      901 cataacaata gcgaaattct cgtatatagt gactatggat atgtggacct actcctattg
      961 gagaccaaca agatcccagt ttactgattc taccgaaacc agcctcatct tggtacatca
     1021 agcgaacctt acgaaaacgt ctactggttt taaatcgctt tcttttcttc ttgaattgag
     1081 attttatttt tagacgcgac aatggtttga gcgtctgctt tcttaggatg ttctggacgt
     1141 ggcgtaatat ttcgccaacc atggcgcttc aacagttgat agaaggcatc acgtgtgtag
     1201 gaacgaccta actccttttt ataagcctga aataaggcat caattgtaac aaattctcct
     1261 gcctctgtag ccttcaaatg acgggcaaga aaggctttct cttcctcaac tgtcatatat
     1321 gcatggttac gaccaccacg tgtttcttga aggagagagt cgagtccgaa ctcctcatat
     1381 tttttacatt ttgctaaatc gttgtttgat tacagtctaa aagctctata atctctttat
     1441 aagatttgcc catcagacga aatataatag attgaaacta gaatagtaca cctctacttc
     1501 taaaacattg ttagaaatc
//
LOCUS       DAVKMJ010000105         1452 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000105 DAVKMJ010000000
VERSION     DAVKMJ010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1452
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.105"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            4..1284
                     /locus_tag="VW348_002159"
     CDS             4..1284
                     /locus_tag="VW348_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEU9746967.1"
                     /translation="MKQNDIVVDLPKTVGAGYGQFWRSRSLYRVVKGSRGSKKSKTTA
                     LNYVIRLLKYPWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESLPEITIK
                     ATGQKILFRGLDDELKITSITVDIGSLCWAWFEEAYQIETEDKFSTVVESIRGSLDVP
                     DFFKQITVTFNPWNERHWLKRVFFDEETRRADTFATTTTYKCNEWLDEVDIKRYEDLY
                     HTNPRRARIVCDGEWGVAEGLIYENVTVKDFNKDELLQDSANKLCIGLDFGFTHDPTA
                     LCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAESRLIEELRS
                     EHGISRIKESRKGKDSIMAGVSKLQGYAIYVHPDCKNIMDEFYSYCYQRDKEGNWLNK
                     PEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
BASE COUNT          467 a          249 c          330 g          406 t
ORIGIN      
        1 cagattaaac aaaacgatat tgtcgttgac ttacctaaga cagtaggagc tggatacgga
       61 cagttctggc gctcaagaag tctttatcgt gtagtcaaag ggtcccgtgg ttcgaagaag
      121 tccaagacaa ccgctttgaa ttatgttatc cgtcttttga agtatccctg ggccaacttg
      181 cttgttattc gtagatactc gaataccaac aagcaatcaa cttatacgga ttttaaatgg
      241 gcgtgtaatg tgttgggtgt gactcatttg tttaaattta acgagtcttt gcctgaaata
      301 accataaaag cgactggtca aaaaatccta ttccgtggtt tggatgatga actcaaaatt
      361 acatctatta cagtcgatat cggtagtctg tgttgggcat ggttcgagga agcatatcaa
      421 attgagactg aagacaagtt cagcacggtt gttgagtcta tccgtggtag cttagatgta
      481 cctgatttct ttaaacaaat cacagtcaca tttaacccgt ggaatgagag gcattggctc
      541 aagcgtgtat tcttcgatga agagacgaga cgggctgaca cattcgctac tacaaccact
      601 tataaatgca atgagtggct tgatgaagtc gatatcaaac gctatgagga tttgtatcat
      661 acgaacccca gacgtgctag aatcgtttgt gatggcgaat ggggagttgc tgaaggttta
      721 atctacgaaa acgtgactgt caaggatttc aataaagatg aattactaca agattcagct
      781 aataaattat gtatcggtct tgactttggt tttactcatg atccaactgc tttgtgttgt
      841 tcgttgataa atgacacgac gaaagagatt tatgtctttg atgaggcgta taaagtcgga
      901 ttgataacca aagaagttgc gaagatgata aaagacaaag gttatcatcg ctcacaaatc
      961 attgctgata gcgcagagtc acggctgatt gaagagctca ggtcagaaca tggcatatct
     1021 agaataaaag agagtcggaa aggtaaggat agtattatgg caggcgtatc caaattgcaa
     1081 ggatacgcta tttatgtgca tccagattgt aaaaacatca tggatgaatt ttatagttac
     1141 tgctaccagc gagataaaga aggcaactgg ttgaataaac cagaggataa aaacaaccac
     1201 ttgatggacg ctttgcgtta cagccttcaa tgtatcgaag gtggaaaagc aaccgtccgc
     1261 agacgttctg attatggtct atagagagga aagacatgta ccaatattta acctatccac
     1321 gggatggata tgatgagggt tctttgaaga aagacctgat ttacaaattg ataacgatac
     1381 ataacactga aagctcacgc ttgaagaatt taaaaagcta ctacatgggt gatcatgcta
     1441 ttttaaatca ca
//
LOCUS       DAVKMJ010000106         1452 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000106 DAVKMJ010000000
VERSION     DAVKMJ010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1452
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.106"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            4..1284
                     /locus_tag="VW348_002160"
     CDS             4..1284
                     /locus_tag="VW348_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEU9746968.1"
                     /translation="MKQNDIVVDLPKTVGAGYGQFWRSRSLYRVVKGSRGSKKSKTTA
                     LNYVVRLLKYSWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESLPEITIK
                     ATGQKILFRGLDDELKITSITVDVGSLCWAWFEEAYQIETEDKFSTVVESIRGSLDVP
                     DFFKQITVTFNPWNERHWLKRVFFDEETRRADTFATTTTYKCNEWLDEVDIKRYEDLY
                     HTNPRRARIVCDGEWGVAEGLIYENVTVKDFNKDELLQDSANKLCIGLDFGFTHDPTA
                     LCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAELRLIEELRS
                     EHGISRIKESRKGKDSIMAGVSKLQGYAIYVHPDCKNIMDEFYSYCYQRDKEGNWLNK
                     PEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
BASE COUNT          463 a          249 c          336 g          404 t
ORIGIN      
        1 cagattaagc aaaacgatat tgtcgttgac ttacctaaga cagtaggagc tgggtacgga
       61 cagttctggc gctcaagaag tctttatcgt gtagtcaaag ggtcccgtgg ttcgaagaag
      121 tccaagacaa ccgctttaaa ctatgttgtc cgtcttttga aatattcctg ggccaacttg
      181 cttgttattc gtaggtattc gaatacaaat aagcaatcaa cttatacgga ttttaaatgg
      241 gcgtgtaatg tgttgggggt gactcatttg tttaaattca atgagtcttt gcctgaaata
      301 accataaaag cgactggtca aaaaatccta ttccgtggtt tggatgatga actcaaaatc
      361 acatctatca cggtcgatgt cggcagtctt tgttgggcat ggttcgagga agcatatcaa
      421 attgagactg aagacaagtt cagcacggtt gttgagtcta tccgtggtag cttagatgta
      481 cctgatttct ttaaacaaat cacagtcaca tttaacccgt ggaatgagag gcattggctc
      541 aagcgtgtat tcttcgatga agagacgaga cgggctgaca cattcgctac tacaaccact
      601 tacaaatgca atgagtggct tgatgaagtc gatatcaaac gctatgagga tttgtatcat
      661 acgaacccca gacgtgctag aatcgtttgt gatggcgaat ggggagttgc tgaaggttta
      721 atctacgaaa acgtgactgt caaggatttc aataaagatg aattactaca agattcagct
      781 aataagttat gtatcggtct tgactttggt tttactcatg atccaactgc tttgtgttgt
      841 tcgttgataa atgacacgac gaaagagatt tatgtctttg atgaggcgta taaagtcgga
      901 ttgataacca aagaagttgc gaagatgata aaggacaaag gttatcatcg ctcacaaatc
      961 attgctgata gcgctgaatt acgactgatt gaagagctca ggtcagaaca tggcatatct
     1021 agaataaaag agagtcggaa aggtaaggat agtattatgg caggtgtatc caaattgcaa
     1081 ggatacgcta tttatgtgca tccagattgt aaaaacatca tggatgaatt ttatagttac
     1141 tgctaccagc gagataaaga aggcaactgg ttgaataaac cagaggataa aaacaaccac
     1201 ttgatggacg ctttgcgtta cagccttcaa tgtatcgaag gtgggaaagc aaccgtccgc
     1261 agacgttctg attatggtct atagagagga aagacatgta ccaatattta acctatccac
     1321 gggatggata tgatgagggt tctttgaaga aagacctgat ttacaaattg ataacgatac
     1381 ataacactga aagttcacat ttgaagaagc ttaaaagcta ctacatgggc gagcatgcta
     1441 tcttaaaaca ca
//
LOCUS       DAVKMJ010000107         1444 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000107 DAVKMJ010000000
VERSION     DAVKMJ010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1444
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.107"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..660
                     /locus_tag="VW348_002161"
                     /pseudo
     CDS             1..660
                     /locus_tag="VW348_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(695..1444)
                     /locus_tag="VW348_002162"
                     /pseudo
     CDS             complement(695..1444)
                     /locus_tag="VW348_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          449 a          245 c          290 g          460 t
ORIGIN      
        1 atagacttaa aaactatctt actgacaatc cagacgctta tttgactgaa atagcttctg
       61 aatttggctg tcatccaact accatccact atgcgctcaa agctatgggc tacactcgaa
      121 aaaaagaacc acacctacta tgaacaagac ccagaaaaag tagccttatt tcttaaaaat
      181 tttaatagtt taaagcacct agcacctgtt tatattgatg aaacaggatt cgatacttat
      241 ttttatcgag aatatggtcg ctcattaaaa ggtcagttaa taagaggtaa agtatctgga
      301 agaagatatc agaggatttc tttggttgca ggtctaacaa atggtgagtt aatcgctcca
      361 atgacttacg aagagatggt gacgagcgac ttttttgaag cttggtttca gaagtttctc
      421 ttaccaacat taaccacacc atcggttatt attatggata atgcaagatt ccatagaatg
      481 ggtaagttag aacttttatg cgaggagttt gggcataaac ttttacctct tcctccctac
      541 tcacctgagt acaatcctat tgagaaaaca tgggcttata tcaaaaagaa cctcaaaaag
      601 gtattaccaa gttgcaatac cttttacgag gctcttttct cttgttcttg tttcaattga
      661 ctatattaga ggcgagacat ttttcggttc tttgtcaact gtagtgggtt gaagaaagcg
      721 aagatctaga aaggacaaat ttcgtccttt cttttttgaa gttttcaaag ttcctaaaac
      781 caaaggcatt gtgcttgata agtttgatga gattattggt ggcttccagt ttggcgttgg
      841 aataaggtaa ttgaagggcg ttgacgattt tctctttatc tttgaggaag gttttaaaca
      901 gagtctgaaa aagaggtgga aaagcaagag ctgatagaga ttatagctga tagagattat
      961 agtggtgttt caagtcttcg aatagctcaa aagtttatct agaatttctt tattagtcaa
     1021 gtgcatacga aaagtagggc gataaaatcg tttatcactc agtttctgac tatcttgttg
     1081 aatgagctcc agtagcgctt gatagccttg tattcatggg atttcggatg atggcttgtg
     1141 ttctgctctc aagaacagtt atgatattga gcttatcaaa gtcctgagca ataaagctca
     1201 tctctatctc ccgattgaaa cagtcactcc ccagactgtt tcaacgtcct aggacataat
     1261 ctcaggaaga cgcgaaaaat catgctcaaa gtgaaaatca ttgatcttgc gaatgacagt
     1321 tgaagttgaa atagacaact gatgatcaat gtcggtcata gaaatctttt caattaactt
     1381 ttgagcaatc ttttggttga taatacgagg gatttggtga ttcttcttga cgatagaagt
     1441 ttca
//
LOCUS       DAVKMJ010000108         1424 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000108 DAVKMJ010000000
VERSION     DAVKMJ010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.108"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..371
                     /locus_tag="VW348_002163"
     CDS             <1..371
                     /locus_tag="VW348_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000231994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746969.1"
                     /translation="IDYENKEIVTQQVYFENGLPDDRDIYCYDFDEIELMQSTGLKDK
                     NGKEIFEGDIVRTTRFLGRADEIGGFYEYDKEFIGIVKQLEGSWVIDTGSDAVCLWTE
                     IEENEIIGNIYENKEFGGRK"
     gene            368..739
                     /locus_tag="VW348_002164"
     CDS             368..739
                     /locus_tag="VW348_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746970.1"
                     /translation="MRPCKYPYSGRRKKQETPSPIFSARPIFDEVPIVEEVKVEFGVE
                     ASMGRIYPETLIHLDISGYGNRVHSVHRFPGILLSVGESIQLKMLFYKRLRNFTTDRF
                     LTFRESDWKFFIRDLVNEFKH"
     gene            812..1216
                     /locus_tag="VW348_002165"
     CDS             812..1216
                     /locus_tag="VW348_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEU9746971.1"
                     /translation="MNKAKELLKELQDLDMDIQSRIDEINELEAGLLSSPKWSEVKVQ
                     GGQTRKVDDVYTQLVVMKEAIEQDTKEVINRKLELGRMINRLKNPKYRAVLRMTYINK
                     GTADSVCYDLNMSRTTYYRLKNEAVLALEEVI"
     gene            1297..1379
                     /locus_tag="VW348_002166"
     tRNA            1297..1379
                     /locus_tag="VW348_002166"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1328..1330,aa:Tyr,seq:gta)
BASE COUNT          476 a          222 c          337 g          389 t
ORIGIN      
        1 ctattgacta cgaaaacaaa gaaatagtga cacaacaagt ttattttgag aatggtttac
       61 cagacgatag agatatctat tgttatgatt ttgacgaaat cgaactcatg caatcaacag
      121 gactcaaaga caagaacggc aaggaaatct ttgaaggcga tattgtacga actactagat
      181 ttttgggtag agctgacgaa attggcggtt tctatgagta tgacaaggaa tttataggga
      241 ttgttaagca gcttgagggt tcttgggtaa ttgatacggg cagtgacgca gtatgtttat
      301 ggactgaaat tgaagaaaat gaaatcatcg gcaacatcta tgaaaataag gagtttggag
      361 gacgcaaatg agaccttgta aatatccata ttcaggaaga agaaaaaaac aagaaacgcc
      421 gtcgccaata ttttctgcac gaccaatttt tgacgaagtt ccaattgtag aagaagttaa
      481 ggttgagttc ggagttgaag ctagtatggg gcgcatatat ccagaaacgt taatacattt
      541 agatatttct ggatacggaa atagagtgca ttcagtacat cgcttccccg gtattttact
      601 gagtgttggt gagtcaatcc aactaaagat gcttttctat aaaagactta gaaattttac
      661 tacagatcgt ttcttgacgt ttagagaatc tgattggaag ttctttatcc gggacctggt
      721 caacgaattt aagcattaaa aaaagccaag acactctctg cctcagctaa tagttctcgc
      781 aaagactatt atatcacaaa ggagacagag agtgaacaag gctaaagagc tcttgaaaga
      841 gttgcaggat ctggacatgg acatccaaag ccgtatagac gaaattaacg agcttgaggc
      901 aggtttgctc tcaagcccta aatggtccga ggttaaagtc caaggtggac agactagaaa
      961 agttgatgat gtctatactc agttggtagt gatgaaagag gctatagagc aggatactaa
     1021 agaggtcatt aacagaaaac ttgaattagg tagaatgatc aataggctta aaaatccaaa
     1081 gtacagggca gtattaagaa tgacttacat caacaaaggc accgctgata gcgtttgtta
     1141 tgatttgaat atgagtcgta caacctacta caggttaaaa aatgaggcgg tcttagcttt
     1201 ggaagaagtt atctaacctc atagtgagct tatgggactt tttggaacag cacggttcta
     1261 aaaatctgtt agaatggtag tatcaagaat tgaaaagaga ggtctcagaa ttggtagatg
     1321 gttacctgta atgtcagggg gctgtaatgg ccttggaggt tcaagtcctc ccctctcctt
     1381 tgagtgtttg tgtcccagaa tgagttaaat cttctgggtg ggga
//
LOCUS       DAVKMJ010000109         1301 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000109 DAVKMJ010000000
VERSION     DAVKMJ010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1301
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.109"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..213)
                     /locus_tag="VW348_002167"
     CDS             complement(<1..213)
                     /locus_tag="VW348_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEU9746972.1"
                     /translation="MNETKKYLVIKAIAQGKKTKKRACVELNLSERQINRLLLAYQQK
                     GKEAFRHGHGNRNRKPKHAIPDEIKER"
     gene            377..529
                     /gene="rpmG"
                     /locus_tag="VW348_002168"
     CDS             377..529
                     /gene="rpmG"
                     /locus_tag="VW348_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEU9746973.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            539..715
                     /gene="secE"
                     /locus_tag="VW348_002169"
     CDS             539..715
                     /gene="secE"
                     /locus_tag="VW348_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEU9746974.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            770..>1301
                     /gene="nusG"
                     /locus_tag="VW348_002170"
     CDS             770..>1301
                     /gene="nusG"
                     /locus_tag="VW348_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEU9746975.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT          410 a          204 c          258 g          429 t
ORIGIN      
        1 acgttctttg atttcatcag ggattgcatg ttttggtttt cgatttctgt ttccgtgtcc
       61 gtgtctgaag gcttcttttc ctttctgttg ataggctagt aacagacgat tgatttgtct
      121 ttcagaaaga ttgagttcga cacaggcccg tttctttgtt ttctttcctt gggctatagc
      181 ttttatcaca agatattttt tcgtttcatt catattcagt tggatccttt tcatatgact
      241 attctaccaa atgggacatt ttcacgttcg atttactaaa gacattatca cattcgaatc
      301 acaatagtca atctatttcg ctaagatgct tgtcaaagcc tagctttctt gttataatgg
      361 ataagatgga ggcgttatgg cactaaaaaa agcaagccta gcttgtgcgg tttgtggttc
      421 gagaaactat tcaatcaaga tcagcggaaa ccccaagcct acacgactag aagtaaataa
      481 attttgtaag cattgtggca agtacactac acacagagaa acgagatagg agagagcgat
      541 gcgttttatt ggagatattt ttagacttct taaagacaca acgtggccaa ctcgcaagga
      601 aagctggaga gattttcgtt ctatcatgga atacacagct ttctttgtag taattattta
      661 catttttgac cagttgattg tttcaggttt gattcgattt attaacattt tttagaagat
      721 tagtggagtt aattacacta gaaatcttct atttatgaaa ggaaatatca tggatagttt
      781 tgataaaggg tggtttgttt tacaaactta ttctggttat gaaaataagg tgaaagaaaa
      841 tctattacaa cgtgcacaaa cctacaatat gttggataat attctacgcg ttgaaattcc
      901 aacacaaaca gtgcaagttg aaaaaaatgg aaagagaaaa gaagtagaag aaaatcgctt
      961 tccaggttat gttcttgtag aaatggtcat gacagatgaa gcttggtttg ttgttcgaaa
     1021 cacaccaaat gttacaggat ttgtcggatc acacgggaac agatcaaaac caactccatt
     1081 attggaacaa gaaattcgtg acattttggt atctatggga caaactgttc aagaatttga
     1141 tttcgatgtt gagattggtc aaactgtacg tattattgat ggtgcttttg cagactacac
     1201 tggtaagatt acagaaattg ataataacaa agtgaaaatg attatctcta tgtttggtaa
     1261 tgacacagtt gcagaagtaa acctaaacca aatcgcagaa t
//
LOCUS       DAVKMJ010000110         1298 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000110 DAVKMJ010000000
VERSION     DAVKMJ010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1298
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.110"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            476..>1298
                     /locus_tag="VW348_002171"
     CDS             476..>1298
                     /locus_tag="VW348_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEU9746976.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFATKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVD"
BASE COUNT          384 a          220 c          279 g          415 t
ORIGIN      
        1 ttctttgagc ttttttcttt ttaaatattg attgtttcta aaagttctag taatattgct
       61 atttctcatt tttccaaata tgttattcaa cttattagct acgtctctat tcatatttgg
      121 gtataaaaca aaaaatcaat tctaacagtt ttatatcaga ataataaata aaaaagcgat
      181 attctagact gtatcaatcc ttttccatta taggagcaac agagtgggag tagtcatcta
      241 aggactaatt tatatatttt tacgagtcag tatcttggga tactggtttt tactttttta
      301 gactttttga ctacttgtta aaactggggt aattttcgac tgtttaatag ttattatgca
      361 aagtctaaaa gattagaatt gtcaaaacaa tccgtctagg cttgatttta tcctttattt
      421 actataaaat gagaaggaaa aatgtcaaac ttttatattg caaataggag aaatcatgac
      481 aaaaacatta aaacgtcctg aggttttatc acctgcaggg actttagaga agctaaaggt
      541 agctgttcag tatggagcag atgctgtctt tatcggtggt caggcctatg gtcttcgtag
      601 ccgtgcggga aactttactt tcgaacagat ggaagaaggc gtgcagtttg cgaccaagta
      661 tggtgccaag gtctatgtag cggctaatat ggttatgcac gaaggaaatg aagctggtgc
      721 tggtgagtgg ttccgtaaac tgcgtgatat cgggattgca gcagttatcg tatctgaccc
      781 agccttgatt atgattgcag cgactgaagc accaggcctt gaaatccacc tttctaccca
      841 agccagtgcc actaactatg aaacccttga gttctggaaa gagctaggct tgactcgtgt
      901 cgttttagcg cgtgaggttt caatggaaga attagctgaa atccgcaaac gtacagatgt
      961 tgaaattgaa gcctttgtcc atggagctat gtgtatttca tactctggac gttgtactct
     1021 ttcaaaccac atgagtatgc gtgatgccaa ccgtggtgga tgttctcagt catgccgttg
     1081 gaaatacgac ctttacgata tgccatttgg gaaagaacgt aagagtttgc agggtgagat
     1141 tccagaagaa ttttcaatgt cagccgttga catgtctatg attgaccata ttccagatat
     1201 gattgaaaat ggtgtggaca gtctaaaaat cgaaggacgt atgaagtcta ttcactacgt
     1261 atcaacagta accaactgct acaaggcggc tgtggatg
//
LOCUS       DAVKMJ010000111         1172 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000111 DAVKMJ010000000
VERSION     DAVKMJ010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1172
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.111"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            231..>1172
                     /locus_tag="VW348_002172"
     CDS             231..>1172
                     /locus_tag="VW348_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEU9746977.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEEGPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFL"
BASE COUNT          411 a          204 c          244 g          313 t
ORIGIN      
        1 taccttagtc aagaattaga tgtttcacta tgtttgagta agttgatgat ttcatttgat
       61 aacaggtttg aaactgttag gctaggtggc caaggctaat catagccttg gtttagctga
      121 aaaaacaggt tcaagggttc ctgttgtcaa atgaaatgtg atttaaggta taagaaaaca
      181 cctctgtgct atacttgttg ttcaccacaa acacaaggaa aggcacagag atgcaagaac
      241 attatacccc aaaagggaaa catttgacaa tagataaccg tcgcttgatt gagcggtgga
      301 agaatgaaaa taagtccaat cgtgaaattg caggcttgtt aggaaaggcg cctcaaacga
      361 ttcataatga agtcaaaaga ggtacaactt tacaacaagt gagaaaaggg ctatacaaaa
      421 aggtctattc tgccgattac gcacaaactg tttaccaatt caatcgaaaa cggtcggtga
      481 aaaagttaat tttaacaaag gaaatcagag agaagatctt acactatcat aagcaaaaat
      541 tttcgcctga aatgatggtt aacaagaagc aagtgaaagt tggtatttca accatctact
      601 actggtttca taatggtcat ttaggattga cgaaggccga catgctttat cccagaaaaa
      661 ggaaaggtgt caagaagcaa gctagtccga actttaagcc ggcaggtaaa tctatcgaag
      721 aaggtcctga cgttattaat cttcgcttgg aaaatggtca ttatgaaatt gataccgtcc
      781 tactgactaa gataaaaaat tattgcctgt tagtcttaac cgaccggcgg agcagacacc
      841 aaattataag gttaattcca aataaaactg ctgaatctgt caatcaggcg cttacgttac
      901 tattagggga gcatcgtatt ctgtccatta ctgcagataa tggttcggag ttcaaacgat
      961 tgtctgaggt atttcctgag gaacatatct actacgcaca tgcttactct tcatgggaga
     1021 gaggttcaaa tgaaaatcat aatcgattaa ttcggagatg gttacctaaa ggaaccaaga
     1081 aaacgactcc gaaagaagta gcttttatcg aaaattggat taacaactac cctaaaaaat
     1141 gcttggacta caagtcgcca agtgaatttc tt
//
LOCUS       DAVKMJ010000112         1053 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000112 DAVKMJ010000000
VERSION     DAVKMJ010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1053
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.112"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..372
                     /locus_tag="VW348_002173"
     CDS             <1..372
                     /locus_tag="VW348_002173"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746978.1"
                     /translation="DGNRESIKRKAFDKTIKDGIIVSVSGTTIGHTPPGKIGLPNSVV
                     QHNATNGDVLGRTYYDARGFKTKDVHFTNHKQPARHPYGKIGEHAHDFVFDDEGKFVS
                     RSTRELTDDERKENQDILWRY"
     gene            360..587
                     /locus_tag="VW348_002174"
     CDS             360..587
                     /locus_tag="VW348_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HEU9746979.1"
                     /translation="MAILDDLQALYDNGWDASFNYNGQVCGIFPNSIYDVVVIIADDE
                     YRASSFDDLISLQIEGKTLPEIMNEVEVQYG"
     gene            736..948
                     /locus_tag="VW348_002175"
     CDS             736..948
                     /locus_tag="VW348_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746980.1"
                     /translation="MEEWKERFKKEYYELKERFQKLDMMIGKYEKGQLEFESKCPIDS
                     LKGQRSTMWNYLRILEQRAKIEEIKL"
BASE COUNT          380 a          145 c          221 g          307 t
ORIGIN      
        1 gatggtaata gagagtctat taaacgtaaa gcgtttgata aaactattaa agatggtata
       61 atagtaagtg tatcagggac tacaattgga cacactccgc ctggcaaaat aggtttgcct
      121 aatagtgtag ttcagcataa tgctacaaac ggagatgtcc ttggtagaac ttactatgat
      181 gctagaggtt ttaaaacgaa agatgttcat tttacaaacc ataaacaacc ggcacgtcat
      241 ccttatggaa aaatcggaga acatgctcat gattttgtat ttgatgatga aggtaagttc
      301 gttagtagga gtactaggga attaacagac gatgaaagaa aggagaatca agatatatta
      361 tggcgatatt agatgattta caagcgttat atgataatgg atgggacgct tcttttaatt
      421 ataatggtca agtatgtggc attttcccta attctattta tgatgttgtt gttattattg
      481 cggacgacga atatagagca tcttcttttg acgatttgat ttctttacag attgaaggga
      541 aaactttacc ggaaatcatg aacgaagttg aagtacaata tggctaaagc acctagagag
      601 atctaagtgc ttttttagta cccagaaagg agactatccg tacgattttc ttgattgtga
      661 atttgaagta aaaagaattt cagtgatagc ttgcgatact atccttatag aagcctaaaa
      721 gaaaggaaca gaaaaatgga agaatggaaa gaaagattta aaaaagaata ctacgaattg
      781 aaagaacgat tccagaagtt agatatgatg attgggaaat acgaaaaagg gcaactagag
      841 tttgaatcta aatgtccgat tgattcgtta aaaggtcagc gttcaaccat gtggaattat
      901 ttaagaattc tagaacaacg tgcaaaaatt gaagaaatta aactataaaa attaaccgca
      961 tcgaaatcga tgcggttttc ctatgcccta accgtatgga atcccgtacg gtttttatat
     1021 tgtccaaact gtaccgatga caataaaagc tgt
//
LOCUS       DAVKMJ010000113         1031 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000113 DAVKMJ010000000
VERSION     DAVKMJ010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1031
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.113"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..>1031
                     /locus_tag="VW348_002176"
     CDS             <1..>1031
                     /locus_tag="VW348_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEU9746981.1"
                     /translation="ILGNTENGIADKVARMALTNQLFQVEVGKYSVSGPNLIKNSDFK
                     NATNEWGSTQNLGRLVKHSFYHNGQKDLMRLSNATKNENFLYSHRFNLERNTDYVLNF
                     RGFNNSALASYDVYILGRRAGESDGFTIVKKVVSSKKLSTSRCEDVSVTFNSGEMDNA
                     YIRFDNNGSSSGTADLYITEVDLYKGYKPRTWQPHPEDAVADANKKLEATQTKMTQLA
                     GSWVVENINSAGDIISGINLGANGHNRFVGKLTHITGETLIDRAVIKSAMVDKLKTGN
                     FEAGSVTTTILDAEAVTAEKLKVDDALIRKLTANDAFIDRLTSKRIFSTKVESVISSS
                     TFLEAYQGR"
BASE COUNT          334 a          187 c          227 g          283 t
ORIGIN      
        1 attttgggca atactgaaaa tggaattgcg gataaggttg ctcgcatggc tctgactaat
       61 caactgtttc aggttgaggt tgggaaatat agtgtaagcg gccctaacct cattaagaat
      121 agtgatttta aaaatgctac gaatgaatgg ggctcaactc aaaatttagg aagattggtt
      181 aagcatagct tttatcacaa cgggcagaaa gaccttatgc gtttaagtaa tgcaactaaa
      241 aacgaaaact ttttgtatag tcaccgtttt aatcttgaac gaaatactga ctatgtactg
      301 aattttagag gatttaacaa cagtgctctc gcaagctatg atgtttatat tttgggacga
      361 agagcaggcg agagcgatgg attcacaatc gttaagaaag ttgttagcag caagaaacta
      421 tctacctcta gatgcgaaga tgtctcagta acttttaatt ccggagaaat ggataatgct
      481 tacattcgtt ttgataacaa tggctcatca tcaggaacag ctgatttgta tattacagaa
      541 gttgacttgt acaaaggtta taaacctaga acatggcaac cacatccaga agatgcagtc
      601 gcagatgcga ataagaagct tgaagcaacg caaacaaaaa tgactcaact agctggctca
      661 tgggtagttg aaaacatcaa ctcggctgga gatatcatct ctggaatcaa tcttggcgcc
      721 aatggacata accgcttcgt tgggaaattg acccacatca ctggagagac cctgattgac
      781 agagcagtca tcaagtctgc catggttgat aagctgaaaa cgggcaattt tgaagctggt
      841 tcggtcacga ctacgatatt agacgctgaa gcggtaactg ctgagaagtt gaaagttgac
      901 gatgcgctta ttagaaaatt aactgcaaat gatgctttta ttgaccgact gacatctaaa
      961 cgtatcttct ctactaaggt tgagtccgtc atttctagtt caaccttcct agaagcctat
     1021 caaggtcgaa t
//
LOCUS       DAVKMJ010000114         1019 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000114 DAVKMJ010000000
VERSION     DAVKMJ010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1019
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.114"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..1017
                     /locus_tag="VW348_002177"
     CDS             <1..1017
                     /locus_tag="VW348_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEU9746982.1"
                     /translation="NIEHDKDNLESSIVRKYEWDIDKVTGGGESYKLYSKSNSKVSIA
                     ILDSGVDLQNTGLLKNLSNHSKNYVPNKGYLGKEEGEEGIISDIQDRLGHGTAVVAQI
                     VGDDNINGVNPHVNINVYRIFGKSSASPDWIVKAIFDAVDDGNDIINLSTGQYLMIDG
                     EYEDGTNDFETFLKYKKAIDYANQKGVIIVAALGNDSLNVSNQSDLLKLISSRKKVRK
                     PGLVVDVPSYFSSTISVGGIDRLGNLSDFSNKGDSDAIYAPAGSTLSLSELGLNNFIN
                     AEKYKEDWIFSATLGGYTYLYGNSFAAPKVSGAIAMIIDKYKLKDQPYNYMFVKKFWK
                     KHYQ"
BASE COUNT          379 a          126 c          199 g          315 t
ORIGIN      
        1 aatatagagc atgacaaaga taacttagaa tcgtcgattg taagaaaata tgaatgggat
       61 atagataaag ttactggtgg aggcgaaagt tataaattat attctaaaag taattctaaa
      121 gtttcaattg ctattttaga ttcaggagtc gatttacaaa atactggatt actgaaaaat
      181 ctttcaaatc actcaaaaaa ctatgtcccc aataaaggat atttaggaaa agaggaggga
      241 gaggaaggaa taatatcaga tattcaagat agattaggtc atggtacggc tgttgtagct
      301 caaattgtag gggatgacaa tattaatgga gtaaatcctc acgttaatat taacgtctat
      361 agaatatttg gtaagtcgtc agctagtcca gattggattg taaaagcaat ttttgatgct
      421 gtagatgatg gcaatgatat tatcaatctt agtactggac aatatttaat gattgatgga
      481 gaatatgagg acggaacaaa tgattttgaa acatttttga agtataaaaa ggctattgat
      541 tacgcgaatc aaaaaggagt aattatagta gctgcattag ggaatgactc cctaaatgta
      601 tcaaatcagt cagatttatt gaaacttatt agttcacgca aaaaagtaag aaaaccagga
      661 ttagtagttg atgttccaag ttatttctca tctacaattt cggtcggagg catagatcgc
      721 ttaggtaatt tatcagattt tagcaataaa ggggattctg atgcaatata tgcgcctgca
      781 ggctcaacat tatctctttc agaattagga cttaataact ttattaatgc agaaaaatat
      841 aaagaagatt ggattttttc ggcaacacta ggaggatata cgtatcttta tggaaactca
      901 tttgctgctc ctaaagtttc tggtgcgatt gcaatgatta ttgataaata caaattaaaa
      961 gatcagccct ataattatat gtttgtaaaa aaattctgga agaaacatta ccagtaaaa
//
LOCUS       DAVKMJ010000115          962 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000115 DAVKMJ010000000
VERSION     DAVKMJ010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..962
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.115"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..>962
                     /locus_tag="VW348_002178"
     CDS             <1..>962
                     /locus_tag="VW348_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate binding domain-containing protein"
                     /protein_id="HEU9746983.1"
                     /translation="ILGNTENGIADKVARMALTNQLFQVEVAKNASNGQNLLQGTKDF
                     SGGWKNKGANWKKHAEKYKGVDVLFKNNSWNGVGQEIDAKIGEVYTFSLWMKSDWKND
                     TVNFYVNRNGSVEKGWGVPSETSVAITSEWKRYSFTFKITVDGFIFPRVERLNQNTNL
                     YIAGLKLEKGSYATPYTEAPEDTDEAIRSVQSQLTGSWAVQNINSAGDIISGINLGAN
                     GHNRFVGKLTHITGETLIDRAVIKSAMVDKLKTANFEAGSVTTTILKAEAVTAEKLKV
                     DNALIRKLTANDAFIDQLISKRIFSTKVESVISSSTFLEAYQGR"
BASE COUNT          312 a          181 c          216 g          253 t
ORIGIN      
        1 attttgggca atactgaaaa tggaattgcg gataaggttg ctcgcatggc tctgaccaat
       61 caactgtttc aggttgaggt ggctaaaaat gccagcaatg gtcaaaattt gttgcaaggc
      121 acaaaagact tctcaggggg ttggaaaaac aagggtgcaa attggaaaaa gcacgctgaa
      181 aaatacaaag gtgttgatgt cctatttaaa aataattcgt ggaatggcgt tggacaagag
      241 attgatgcaa aaattggtga agtctataca ttcagcttat ggatgaagag cgactggaag
      301 aatgatacag taaatttcta tgtaaataga aatggatctg ttgagaaagg ttggggtgtt
      361 ccatctgaaa catcggtcgc tataacaagt gaatggaaac gttactcatt taccttcaaa
      421 attactgtgg acggcttcat ctttcctcgt gtagaacgac ttaatcaaaa tacaaatcta
      481 tatattgcag gtcttaaact tgaaaaagga tcgtatgcaa caccgtacac cgaagctcct
      541 gaagacacgg acgaagcgat tcgctctgtt caaagccaac taactggctc atgggcagtt
      601 caaaacatca actcggctgg agatatcatc tctggaatca atcttggcgc caatggacat
      661 aaccgcttcg ttgggaaatt gacccacatc actggagaga ccctgattga cagagcagtc
      721 atcaagtctg ccatggttga taagctcaaa acggccaatt ttgaagctgg ttcggtcacg
      781 actacgatat taaaagctga agcggtaact gctgagaagt tgaaagttga caatgcgctt
      841 attagaaaat taactgcaaa tgatgctttt attgaccaac tgatatctaa acgtatcttc
      901 tctactaagg ttgagtccgt catttctagc tcaaccttcc tagaagccta tcaaggccga
      961 at
//
LOCUS       DAVKMJ010000116          961 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000116 DAVKMJ010000000
VERSION     DAVKMJ010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..961
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.116"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..863
                     /locus_tag="VW348_002179"
                     /pseudo
     CDS             1..863
                     /locus_tag="VW348_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            856..>961
                     /locus_tag="VW348_002180"
     CDS             856..>961
                     /locus_tag="VW348_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEU9746984.1"
                     /translation="MDRNIDQELVSIIIPTHNRYESLIRAVKSCLHQSY"
BASE COUNT          354 a           86 c          197 g          324 t
ORIGIN      
        1 tcaactaatt attttttata tatgttaaaa aaacttgaca agaatggatt tggaaaggtt
       61 aagacagtga taacatgcca tggatgggtt gaatataact taaaaaagaa attcttgact
      121 tattttgatt tttggacata ttctatggga gatgctttta tttgtgtatc tgaaactatg
      181 aaaaaagatt ggagagtata ataaaaaata agaagataat tgcaataaat aacggaatta
      241 atgtatcaaa tagcgattta gatgtagtag gtgttcaaga ctttaaaaaa gaattttgta
      301 ttccaaataa caaaaaaatc atttgttata ttggaaggtt ggatccagaa aaaaggccgg
      361 atagattcct tgaatttgca gaaaaattat ttttagtcag agaagatgtg atttttatta
      421 tggctggaaa tggtagtatg tgggctgctt tgaaagaaaa aatttgccat ttgaaatgta
      481 gagataattt caggttactt ggtgaaatct atccagctac tatagtttac caaatatcgg
      541 atttattgta tattccttct gatacagaag gaatacctat gtgtgtttta gagtcaatgt
      601 cacaaggaac tccggtttta gctagtaatg ttggcgggtt aagtgaaatt attgaacata
      661 gggttgatgg atttttattt gagaaggaag atgttgaggg agtgtgtgct tgtgctaatt
      721 ttttactcaa tgattctgag tatttgaaat atataggtga gaatagtaaa tcaaaaataa
      781 gaaaacattt ttctgtgcaa aaaatgtttg tagaaaccat gagagtatat gatgaattat
      841 tagagaagag tagtcatgga taggaatata gatcaagaat tagtaagtat tataatacca
      901 acacataata ggtatgaatc tctgattaga gctgtgaaaa gttgtttaca tcaaagttat
      961 a
//
LOCUS       DAVKMJ010000117          886 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000117 DAVKMJ010000000
VERSION     DAVKMJ010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..886
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.117"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(122..310)
                     /gene="pneA2"
                     /locus_tag="VW348_002181"
     CDS             complement(122..310)
                     /gene="pneA2"
                     /locus_tag="VW348_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA2"
                     /protein_id="HEU9746985.1"
                     /translation="MKNDFVIGKSLKELSLEEMQLVYGGTDGADPRSTIICSATLSFI
                     ASYLGSAQTRCGKDNKKK"
     gene            complement(317..541)
                     /gene="pneA1"
                     /locus_tag="VW348_002182"
     CDS             complement(317..541)
                     /gene="pneA1"
                     /locus_tag="VW348_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit PneA1"
                     /protein_id="HEU9746986.1"
                     /translation="MTNFNSNEKFCGKSLKSLSADEMSLIYGASDGAEPRWTPTPIIL
                     KSAAASSKVCISAAVSGIGGLVSYNNDCLG"
BASE COUNT          285 a          174 c          107 g          320 t
ORIGIN      
        1 tttcatttac ttacctcaaa cctatacgac ttactattgt tttaaaaaaa aacctctctc
       61 aaaattatta gttacgagag aggaaaataa agagcaactt ttatttttaa aattgaatat
      121 tttatttttt cttgttgtct ttgccacaac gagtctgagc tgaccccaaa tatgatgcaa
      181 taaaacttaa tgtagcagaa catataattg ttgatctagg gtcagcacca tctgtgccac
      241 cataaaccaa ttgcatttct tcaagagata attctttcaa actctttccg attacaaaat
      301 catttttcat tttaatttac cccaaacaat cattattgta gctaactagc cccccaatac
      361 cagaaacagc tgcactaatg catactttcg agctagctgc agctgatttc aaaataatag
      421 gagtaggcgt ccaacgtggc tctgcaccat cagatgcacc ataaattaaa ctcatttcat
      481 cagcagacaa tgattttaaa ctttttccac aaaatttttc gtttgaatta aagttggtca
      541 taagtaataa ctcctcctta taaaaagtta aataagttgc tctatatttt tcgttttttc
      601 agataaatta taattctctc attctcgtgc aaaatatcgg gttttaatcc gccttcccaa
      661 catcaagacc attggacttc ttttgcgatt gcactcgaat ctccaattgt ttattcttct
      721 gaataaactg ttggtaagga attgtattac taaacataaa aacacctagc aatgcaaatg
      781 taactaattt tttaattcca cgtttttttc tcatgcaatg aaaccccttt ctttttcctt
      841 gtttttattc taacagatat attttattta gtcaagtatt tttatg
//
LOCUS       DAVKMJ010000118          877 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000118 DAVKMJ010000000
VERSION     DAVKMJ010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..877
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.118"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            97..552
                     /locus_tag="VW348_002183"
     CDS             97..552
                     /locus_tag="VW348_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746987.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGHNFSSVSSS
                     SQTAKYEETGYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEITVKIVSAKPTYPDKILVKNPDNIKDTEKMPLLKN"
     gene            549..695
                     /locus_tag="VW348_002184"
     CDS             549..695
                     /locus_tag="VW348_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746988.1"
                     /translation="MKEANKNHPAGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVT
                     KYAR"
BASE COUNT          322 a          129 c          161 g          265 t
ORIGIN      
        1 tttttatgtg cagagttata gtggcttgat gctgggaaag tacactgtga ctgctaaaac
       61 attcctagaa gttgctttga tttacctaat ctatttatgc aaattttatg ttattttact
      121 ataacagttg ttgctaagcc aaataatagt ggggaagttc atttagacgt aagcattgaa
      181 gataatcagg gaggtagtgg gcataatttc agttctgttt caagtagctc acaaacagct
      241 aaatatgaag aaactggtta taataacaat tcatcattat atataacgat tgataaaacg
      301 tctgatgcaa cagctctttt gaaattaaag ttgaataatg ttgataatca acctgctact
      361 gaagttccta gttcaggaat tactgtaaaa ttaaatgcta aagataatgc tggaaactgg
      421 acaagtgctt cgaataaaaa agaaataaca gtaaaaattg tttctgctaa accgacatat
      481 ccagacaaaa tcttagtgaa aaatcctgat aatataaaag atacagaaaa aatgccatta
      541 ttgaaaaatt gaaagaggca aataaaaatc atccagcagg agctccaacc tttgctaaag
      601 gtgaaggaga gcatgcaaat gatattgtag caacttattc agatggtaca acttattatg
      661 taccgttaaa tgatgtgaca aaatatgcga ggtagtggct gtaccactca cttattcacc
      721 tccccgtgat ttgtagtagt gataggcttt ctcactatta ttataaaaca aaataaagat
      781 cacaacactt tttcattctg tgttgtgcct tgagtgaaac gaaaggaatg aattataaat
      841 atgaaaagta tagtcactag catagatgag cgcttgc
//
LOCUS       DAVKMJ010000119          875 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000119 DAVKMJ010000000
VERSION     DAVKMJ010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..875
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.119"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..>875
                     /locus_tag="VW348_002185"
     CDS             <1..>875
                     /locus_tag="VW348_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEU9746989.1"
                     /translation="NGKASKSELTQTAEELASRIASVQASGRNLFLNSLFKQDISKTG
                     IWTTSTYTATIDSESKYLGYNALKIIGLNPSGRDGGNPKVTYPVLGQFGKVIPGSTTN
                     QDVTISFYAKANKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNESKQTTN
                     EWLFNFNQEGTVWIWMPKFEISDVDTSYSEAPEDIEGQISTVESTFKQRVNSLEAGVN
                     RLTEGLRTKADISALNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQEIL
                     NATKDKADKTLVVSEA"
BASE COUNT          294 a          164 c          203 g          214 t
ORIGIN      
        1 aatggtaaag ccagcaagtc agaactcacg cagacagctg aggagctagc tagtcggatt
       61 gcgagtgtgc aggcatccgg tcgaaatcta ttcttgaact cactattcaa gcaggatatt
      121 tcaaaaacag gaatttggac aacgagtaca tatacggcta ctatcgatag cgaaagtaag
      181 tatcttggat ataacgctct taaaattata ggtctgaatc catctggccg tgatggaggg
      241 aatcccaagg ttacttatcc agttctgggt caattcggga aagtaattcc cggaagtacg
      301 actaatcaag atgtaaccat tagtttttat gctaaggcaa ataaaaatgg aataatgcta
      361 agatctcgat tagggaatat cggatataaa actggaaatg tgacattgtc gacagaaatt
      421 aaacgatatg ttgtccatat tccaaaaggt tggacaaacg aatccaagca gaccacaaat
      481 gaatggttgt tcaatttcaa ccaggaagga accgtttgga tttggatgcc gaagtttgaa
      541 ataagcgatg tagatacttc ttattcagaa gctcctgaag atatagaagg tcagatttca
      601 acagttgaat cgacctttaa acaacgagtc aactcgctcg aagctggtgt gaatcgtctg
      661 actgaaggcc ttagaaccaa agccgatatc agcgcactca acgtgactgc tgaaaatatc
      721 cggcaatctg tgaagagtct tgagacagac acgcagaaca agctaaatca gaagttgagt
      781 caggctgaat ttgaggtgcg agccggctct atccgtcagg aaatcctgaa cgcaaccaag
      841 gataaggcag ataagacttt agttgtatct gaagc
//
LOCUS       DAVKMJ010000120          866 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000120 DAVKMJ010000000
VERSION     DAVKMJ010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..866
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.120"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(1..265)
                     /locus_tag="VW348_002186"
                     /pseudo
     CDS             complement(1..265)
                     /locus_tag="VW348_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(500..811)
                     /locus_tag="VW348_002187"
     CDS             complement(500..811)
                     /locus_tag="VW348_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9746990.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCSFCFSRFNPGCQNHKERYF
                     K"
BASE COUNT          275 a          171 c          138 g          282 t
ORIGIN      
        1 catccacagc cgccttgtag cagttggtta ctgttgatac gtagtgaata gacttcatac
       61 gtccttcgat ttttagactg tccacaccat tttcaatcat atctggaatg tggtcaatca
      121 tagacatgtc aacggctgac attgaaaatt cttctggaat ctcaccctgc aaactcttac
      181 gttctttccc aaatggcata tcgtaaaggt cgtatttcca acggcatgac tgagaacatc
      241 caccacggtt ggcatcacgc atactctaga cgcaattcta atcttttaga ctttgcataa
      301 taactgttaa acagttgaaa attaacccag ttttaacaag tagtcaaaat accagataaa
      361 ggaaaaaagt ctttaaaatc ttaaaaacgc atagtatcag gtattgaaca atcttgatat
      421 tatgcgtttt attgtgggaa gatttacttc attttctctt ggaattgagt tttctcctac
      481 ttcaaaacta gatgatttgc tatttaaaat agcgttcctt atgattttgg caacctggat
      541 taaagcgaga aaaacaaaag gagcaactta aactttcttt atattgctta tatgttagta
      601 gttttagaca aacaccacat aaaataggct tatcctgtat caaagataag ggatacggct
      661 caaaagggtg attttctaat gaatcatgac accgataaca agcatagtac tttttacaat
      721 catagcattg taaagcaata atatccaact tgctatggta atgaatgcat cttgtttgct
      781 tatccactaa gaaaccctgt gcctctatca tttccttttc ctttcttaag cacgaactgt
      841 gacgctggtt ccatcttcct tataaa
//
LOCUS       DAVKMJ010000121          838 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000121 DAVKMJ010000000
VERSION     DAVKMJ010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..838
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.121"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..792
                     /locus_tag="VW348_002188"
     CDS             <1..792
                     /locus_tag="VW348_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY-like element IS1202 family transposase"
                     /protein_id="HEU9746991.1"
                     /translation="FDKQETLNAYYHVLEQILANHGIPLQMKTDKRTVFTYQASNSKK
                     MEDDTYTQFGYACHQLGILLETTSIPQAKGRVERLNQTLQSRLPIELERNKIHTLEEA
                     NTFLLSYIQTFNEQFGNKTKLSVFEEAPNPSERNLILARLAERVVDSGHHIRFQNRCY
                     IPTEQGKEVYFIRKTKALVLKAFDGDIYLNIADKIYHTKELLDHELYSKNFEQEPEQK
                     KERRKYIPPQTHPWKLTSFKQYLHKNKKDYEEFTSEEIHSPQLQV"
BASE COUNT          299 a          200 c          136 g          203 t
ORIGIN      
        1 tttgacaaac aagagacctt gaatgcctac taccatgtcc tcgaacaaat cttagccaat
       61 cacggcattc cccttcaaat gaaaactgat aagagaacgg tctttaccta tcaagcatcc
      121 aactctaaga aaatggagga cgacacctat acacaatttg gatacgcctg tcaccaacta
      181 gggattctcc ttgagaccac ctctatccct caagctaaag ggagggtcga aagactcaat
      241 cagacactac aatcacgcct gcctatcgaa ctggaacgaa acaagattca tacattggaa
      301 gaagccaata ctttccttct ttcctacatc caaaccttta atgaacagtt tggaaataag
      361 acaaaactct ctgtttttga ggaggctcct aacccctctg aacggaatct cattctagct
      421 agactggcgg agagagtcgt cgatagtgga caccatatcc gattccaaaa ccgttgctat
      481 attcctaccg aacaaggaaa agaagtctat ttcatcagaa agacgaaagc attagttcta
      541 aaagcatttg atggtgacat ctacctcaat atcgctgaca aaatctatca cacaaaggag
      601 ctactagatc atgaactcta ttcgaaaaac tttgaacaag aaccagaaca aaaaaaagaa
      661 agacgcaagt atatccctcc acaaacccat ccgtggaaac tcacatcttt caaacaatac
      721 cttcataaaa acaaaaagga ttatgaagag tttactagtg aggagattca ttctcctcaa
      781 ctacaagtat aatctatttt tcgctaaatg ggaagctttt ccttaaagga agtcactc
//
LOCUS       DAVKMJ010000122          818 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000122 DAVKMJ010000000
VERSION     DAVKMJ010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..818
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.122"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..>818)
                     /locus_tag="VW348_002189"
     CDS             complement(<1..>818)
                     /locus_tag="VW348_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEU9746992.1"
                     /translation="VLKNMKDKKNLNELRKVLEARPNDPNIQRLLADLDSPAYSFRMK
                     RLERLSDDLDRMRESIYHSEKTGSDAFYSDLMKDSYYKATFDLQQQTGLAYGFSGLPE
                     NEIKHLQSFSWVGDGSTYSTDIWKNTGKLTSSIKDELLISLMTGRDTRETAQAIAERF
                     NVGQNDARRLVRTESAFFHNQMELLSYEEADIEKYIFVAVLDKRTSRICQEHDNQVYD
                     RDKAVPGVNCPPMHPWCRSTTVGYDEDADYSKLKRRARNPETGKVEYVPADMTY"
BASE COUNT          196 a          195 c          169 g          258 t
ORIGIN      
        1 ttataagtca tatcggcagg cacgtactca actttacctg tctctggatt ccttgctctg
       61 cgcttcaact tgctgtagtc tgcgtcctca tcgtatccga cagtagtaga cctacaccaa
      121 gggtgcatag gcggacaatt gacaccaggg acagccttat ccctatcata gacctgattg
      181 tcatgctcct gacaaatgcg tgatgtacgc ttgtctaaga cggccacaaa gatatacttt
      241 tctatgtctg cttcttcata gctgagtagc tccatctggt tatgaaaaaa ggcggattct
      301 gttcgaacca aacgccttgc atcgttctga cctacattga acctctcagc aattgcttgt
      361 gcagtttctc gtgtatctct gcctgtcatg aggctaatga ggagttcatc ttttatgctg
      421 gaagtaagtt ttcctgtatt cttccagatg tctgttgagt acgtacttcc atctcctacc
      481 caactaaaag actgtagatg tttaatctcg ttctcaggaa gcccagaaaa gccatatgct
      541 agtcctgtct gctgttgtag gtcaaaggta gccttgtagt aactatcctt catcaggtcg
      601 ctataaaagg catctgagcc tgtcttctcc gaatgataga tagattcacg catacgatct
      661 aaatcgtcgc tcaaacgctc taggcgcttc atgcggaaag aataagctgg gctgtctaag
      721 tcagctagta atctttggat gttcgggtca ttcggtctcg cttcaagtac tttacgaagt
      781 tcattcagat ttttcttgtc tttcatgttc ttcaagac
//
LOCUS       DAVKMJ010000123          806 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000123 DAVKMJ010000000
VERSION     DAVKMJ010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..806
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.123"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..>806
                     /gene="phtD"
                     /locus_tag="VW348_002190"
     CDS             <1..>806
                     /gene="phtD"
                     /locus_tag="VW348_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HEU9746993.1"
                     /translation="YTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHS
                     HWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKGAEAIYNRVKAAKKVPL
                     DRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLEDLLATVKYYV
                     EHPNERPHSDNGFGNASDHVQRNKNGQADTNQTEKPNEEKPQTEKPEEDKEHDEVSEP
                     THPESDEKENHAGLNPSADNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSV"
BASE COUNT          285 a          160 c          180 g          181 t
ORIGIN      
        1 tacactgatg atgagattca agtagccaag ttggcaggca agtacacaac agaagacggt
       61 tatatctttg atcctcgtga tataaccagt gatgaggggg atgcctatgt aactccacat
      121 atgacccata gccactggat taaaaaagat agtttgtctg aagctgagag agcggcagcc
      181 caggcttatg ctaaagagaa aggtttgacc cctccttcga cagaccatca ggattcagga
      241 aatactgagg caaaaggagc agaagctatc tacaaccgcg tgaaagcagc taagaaggtg
      301 ccacttgatc gtatgcctta caatcttcaa tatactgtag aagtcaaaaa cggtagttta
      361 atcatacctc attatgacca ttaccataac atcaaatttg agtggtttga cgaaggcctt
      421 tatgaggcac ctaaggggta tactcttgag gatcttttgg cgactgtcaa gtactatgtc
      481 gaacatccaa acgaacgtcc gcattcagat aatggttttg gtaacgctag cgaccatgtt
      541 caaagaaaca aaaatggtca agctgatacc aatcaaacgg aaaaaccaaa cgaggagaaa
      601 cctcagacag aaaaacctga ggaagataag gaacatgatg aagtaagtga gccaactcac
      661 cctgaatctg atgaaaaaga gaatcacgct ggtttaaatc cttcagcaga taatctttat
      721 aaaccaagca ctgatacgga agagacagag gaagaagctg aagatactac agatgaggct
      781 gaaattcctc aagtagagca ttctgt
//
LOCUS       DAVKMJ010000124          791 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000124 DAVKMJ010000000
VERSION     DAVKMJ010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.124"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            16..>791
                     /locus_tag="VW348_002191"
     CDS             16..>791
                     /locus_tag="VW348_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001856457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HEU9746994.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     LAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKS"
BASE COUNT          250 a          165 c          131 g          245 t
ORIGIN      
        1 attagaaaga ttcatatgga acaattacat tttatcacaa aactgctcga tattaaagac
       61 ccaaacatca agattctaga tatcatcaat atggataccc acaaagaaat tatcgctaag
      121 ctggattatg aggctccatc ttgccctgat tgtggaagtc taatgaagaa atatgacttt
      181 caaaaaccgt ctaagatccc ttacctcgaa acaactggta tgccttctag aattctcctt
      241 agaaaacgcc gtttcaagtg ctatcactgt tcaaaaatga tggttgctga gactcccctg
      301 gtaaagaaaa atcaccaaat ccctcgtatc atcaaccaaa aaattgctca aaagttaatt
      361 gaaaaaattt ctatgactga tattgcccat cagctggcca tttcaacttc aactgtcatt
      421 cgcaagctca atgactttca ctttgagcat gatttttctc ggcttccaaa gattatgtct
      481 tgggatgagt atgccttcac taagggaaag atgagtttca ttgcgcaaga ttttgataat
      541 cttaatatta tcactgttct tgaaggcaga acacaagctg tcatccgaaa tcactttctt
      601 cgctacgata gagccgttcg ttgtcaagtg aaaatcatta cgatggatat gtttagtcct
      661 tactatgact tggctaaaca gctttttccg tgtgctaaaa tcgttctaga tcgtttccat
      721 attatccaac atctcagccg tgccatgagt cgttttcgtg ttcaaattat gaatcagttt
      781 gaacgaaaat c
//
LOCUS       DAVKMJ010000125          737 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000125 DAVKMJ010000000
VERSION     DAVKMJ010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..737
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.125"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..>737
                     /locus_tag="VW348_002192"
     CDS             <1..>737
                     /locus_tag="VW348_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEU9746995.1"
                     /translation="NGKASKSELTQTAEELSSKIASVQASGRNLFLNSLFKQDISKTG
                     IWTTSTYTAAIDSESKYLGHKALKIIGLNPSGRDGGNPKVTYPALGQFGKVIPGSTTN
                     QDVTISFYAKANKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNESKQTTN
                     EWLFNFNQEGTIWIWMPKFEISDVDTSYSKAPEDIEGQISTVESNFKQRADSLEAGVS
                     RLTEGLRTKADISALNVTAENIRQSVK"
BASE COUNT          250 a          134 c          166 g          187 t
ORIGIN      
        1 aatggtaaag ccagcaagtc agaactcacg cagacagctg aggagctctc tagtaagata
       61 gcgagtgtgc aggcatccgg tcgaaatcta ttcttgaact cactattcaa gcaggatatt
      121 tcaaaaacag gaatttggac aacgagtaca tatacggctg ctatcgatag cgaaagtaag
      181 tatcttggac acaaggctct taaaattata ggtttgaatc catctggtcg tgatggaggt
      241 aatcccaagg ttacttatcc agctctgggt caattcggga aagtaattcc cggaagtacg
      301 actaatcaag atgtaaccat tagtttttat gctaaggcaa ataaaaatgg aataatgcta
      361 agatctcgat tagggaatat cggatataaa actggaaatg tgacattgtc gacagaaatt
      421 aagcgatatg ttgtccatat tccaaaaggt tggacaaacg aatccaagca gaccacaaat
      481 gaatggttgt tcaatttcaa ccaggaagga accatttgga tttggatgcc gaagtttgaa
      541 ataagcgatg tagatacttc ttattcaaaa gctcctgaag atatagaagg tcagatttca
      601 acagttgaat ccaactttaa acagcgtgct gattcactcg aagctggtgt aagccgtctg
      661 actgaaggcc ttagaaccaa agcggatatc agcgcactca atgtgactgc tgaaaatatc
      721 cggcaatctg tgaagag
//
LOCUS       DAVKMJ010000126          735 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000126 DAVKMJ010000000
VERSION     DAVKMJ010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..735
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.126"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(58..>735)
                     /locus_tag="VW348_002193"
     CDS             complement(58..>735)
                     /locus_tag="VW348_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEU9746996.1"
                     /translation="LADTPEDAKVAMKILSEEGLLELPGDSARAEFLKNTLDESATEI
                     LRTALKEDIYTFSHVPNLTDENFAGNTSGVAMEFKLMGLEMITKTKEANYKRGLRQRI
                     AIFAHYLGMKQIALESHSIVPQFSRGLPKNLLEISQIVNNLEGKVTNRQLISLLPFVE
                     DPDAELEALEEEKKKNMEDMPMFNKDNTKPEDEVEDEESGVLGEEESQSDLPADGQGR
                     KAGRPVR"
BASE COUNT          177 a          186 c          132 g          240 t
ORIGIN      
        1 ttatcgaaaa tcttattgat ttccttatcc aagtaagtct tagcttcctg atagacctta
       61 tcgaactggt ctgcctgctt ttcggccttg tccatctgct ggtaaatcag attggctttc
      121 ctcttcgccc aatactcctg attcttcatc ctctacctcg tcttcgggtt tcgtgttgtc
      181 tttgttgaac atcggcatgt cttccatgtt cttctttttc tcttcttcca aggcttccag
      241 ctcagcgtca gggtcttcca caaacggcaa gagagaaata agctgtctat tggtcacttt
      301 gccttccaaa ttgttcacaa tctgagagat ttctaataag ttcttaggca aaccacgact
      361 gaattgtgga acgattgaat gagactctaa agcaatctgc ttcatgccta agtaatgagc
      421 aaaaatcgca atacgctgac gcaatcctcg cttatagttc gcttccttgg tcttagtaat
      481 catctcaagg cccatcagct taaattccat ggctacgcct gatgtattcc ctgcgaaatt
      541 ctcatcagtc aaattaggca catggctaaa tgtgtagatg tcctctttaa gagctgtacg
      601 caagatttca gtagcacttt cgtccagcgt attcttcaag aactcagccc ttgcactatc
      661 gcccggcaat tccaaaagac cttcttcaga aagaatcttc attgctacct tagcgtcttc
      721 tggagtgtct gctaa
//
LOCUS       DAVKMJ010000127          653 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000127 DAVKMJ010000000
VERSION     DAVKMJ010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..653
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.127"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..>653
                     /locus_tag="VW348_002194"
     CDS             <1..>653
                     /locus_tag="VW348_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEU9746997.1"
                     /translation="SKMKVGGRNLWIKSKTVGAVIEKLPENHVTGQKECYRLENNSTL
                     TFNLEPDFSSRLYQKVTFSAWIKYENVVQGRNFWNVFNCFKHYLFRKNSETGVQSGPD
                     YATLGMYKGSADWKYITFTYDYSEKTNFDQLKTSLRFNLEGATSGTAWVTGIKVEIGS
                     VATDWSPAPEDGENELLVAKTEFKRTADGLSTKMAAVESYVGQDGQRQEALQRYTRE"
BASE COUNT          219 a          111 c          155 g          168 t
ORIGIN      
        1 tcaaaaatga aggtgggagg ccggaatcta tggataaaat ccaagacggt tggagctgta
       61 attgaaaaat tacctgaaaa ccatgtcaca ggtcaaaaag aatgttatag gttagagaac
      121 aactctactt taacgttcaa ccttgaacca gatttcagct caaggttgta tcaaaaagtt
      181 acttttagcg cttggatcaa gtacgaaaat gtagtccaag gtcgaaactt ttggaatgta
      241 tttaattgct tcaaacatta tctttttaga aaaaatagtg agaccggagt acagagtggt
      301 ccagattatg ctacgcttgg tatgtataaa ggttcggcag attggaaata tattacattc
      361 acttatgact actctgaaaa aacaaatttt gatcaattga agacatcatt gcgattcaat
      421 cttgaaggtg ctacaagcgg tacagcttgg gtaacaggaa tcaaggttga aatcggtagt
      481 gtggcgacgg actggtcacc agcaccagaa gacggagaaa atgagctttt agtcgctaaa
      541 accgagttca agaggacagc tgatggccta tctactaaga tggcagcagt tgagagctat
      601 gttggtcaag acggtcagcg acaggaagcc ctacagcgct atactcgtga gga
//
LOCUS       DAVKMJ010000128          637 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000128 DAVKMJ010000000
VERSION     DAVKMJ010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..637
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.128"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..523
                     /locus_tag="VW348_002195"
                     /pseudo
     CDS             1..523
                     /locus_tag="VW348_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          214 a          114 c          118 g          191 t
ORIGIN      
        1 tgaaatagct tctgaatttg gctgtcatcc aactaccatc cactatgcgc tcaaagctat
       61 gggctacact cgaaaaaaaa gaaccacacc tactatgaac aagagccaga aaaagtagcc
      121 ttatttctta agaattttaa tagtttaaag cacctagcac ctgtttagat tgatgaaaca
      181 ggattcgata cttattttta tcgagaatat ggtcgctcat taaaaggtca gttaataaga
      241 ggcaaagtat ctggaagaag atatcagaga atttctttgg ttgcaggtct aacaaatgaa
      301 tggtgagtta atcgctccaa tgacttacga agagacgatg acgagcgact tttttgaagc
      361 ttggtttcag aagtttctct taccaacatt aaccacacca tcagttatta ttatggataa
      421 tgcaagattc catagaatgg gtaagttaga actcttgtgt gaagagtttg ggtataaact
      481 tttacctctt cctccctact cacctgagta caatcctatt gaggctctat aatatttgta
      541 gtgggtaaat cccctatgga tattatggag cctatttttg tgtagaaaaa aagtcccata
      601 agatctataa tgaaaagcga tcaaacaact cattaga
//
LOCUS       DAVKMJ010000129          598 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000129 DAVKMJ010000000
VERSION     DAVKMJ010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..598
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.129"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..513
                     /locus_tag="VW348_002196"
                     /pseudo
     CDS             1..513
                     /locus_tag="VW348_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          224 a          105 c          105 g          164 t
ORIGIN      
        1 taaaccacca agtaaaagga acaaaaccaa gaaaagttga tagagataga cttaaaaact
       61 atcttactga caatccagac gcttatttga ctgaaatagc ttctgaattt ggctgtcatc
      121 caactaccat ccactatgcg ttcaaagcta tgggctacac tcgaaaaaaa gaaccacacc
      181 tactatgaac aagacccaga aaaagtagcc ttatttctta agaattttaa tagattaaag
      241 cacctagcac ctgtttagat tgacgaaaca ggattcgata cttattttta tcgagaatat
      301 ggtcgctcat taaaaggtca gttaagaaga ggcaaagtat ctggaagaag atatcagagg
      361 atttctttgg ttgcaggtct aacaaatggt gagttaatcg ctccaataac ttacgaagag
      421 acgatgacga gcgacttttt tgaagtatgg tttcagaaat ttctcttacc aacattaaac
      481 acaccatcgg ttattatagt aaaacgaaat aagaatagga caaatcgatc aggacagtaa
      541 aatcgaattc taacaatgtt ttagaagtag atgtgtacta ttctagtttc aatctact
//
LOCUS       DAVKMJ010000130          570 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000130 DAVKMJ010000000
VERSION     DAVKMJ010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..570
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.130"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..>570)
                     /locus_tag="VW348_002197"
     CDS             complement(<1..>570)
                     /locus_tag="VW348_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEU9746998.1"
                     /translation="NYKTVANHAKDIADTATGYFMGNPIKYNNTADGDIDELLTAFDG
                     AEIDQVDAQNALNMAIYGRAYEYIYAKEGMTELDSTSIDPENTFMVYDDSIERKPLFA
                     VYYYEVKDDTKDTTKHQAEVFTENLHYHMVLRSTDSGTTQSEEATPHNLGQIPIIEYR
                     NNHFAIGDYEQQISLIDAYNSLMGNRVND"
BASE COUNT          146 a          131 c          115 g          178 t
ORIGIN      
        1 ttatcattga cacgattccc catcaaggaa ttataagcgt ctatcaagct aatttgttgc
       61 tcgtagtcgc caatcgcaaa gtgattattg cgatactcga taattgggat ttgaccaagg
      121 ttgtgaggtg ttgcctcctc gctctgagtt gttcctgaat ctgtacttct cagcaccatg
      181 tgatagtgca gattttcggt aaagacctca gcctggtgct tggtagtgtc tttcgtatcg
      241 tcttttactt catagtaata gaccgcaaac aaaggcttcc gctcaatact atcatcgtag
      301 accatgaaag tattctccgg atcaatacta gttgaatcca actcagtcat accctcttta
      361 gcatagatgt actcgtaagc acggccgtag atagccatat ttagtgcgtt ctgcgcatcc
      421 acttggtcaa tctcagcacc atcaaaggct gtaagtagtt catcaatatc accgtcagca
      481 gtattgttat acttgatagg attgcccata aaatagcccg tagccgtgtc tgcgatatcc
      541 ttggcatgat tagctaccgt cttgtaattg
//
LOCUS       DAVKMJ010000131          476 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000131 DAVKMJ010000000
VERSION     DAVKMJ010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.131"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..>476)
                     /locus_tag="VW348_002198"
     CDS             complement(<1..>476)
                     /locus_tag="VW348_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEU9746999.1"
                     /translation="FDQGGGRWISGVNQFSVGMGNGAGHGVRTAFWANWGNNWNYAGP
                     KAWNVNTDGKMYCRNEVGFYDQVDFSNSSRANFYGNTTFSRSPVFSNGIELGSKDVLG
                     DGWNPKGGRNAVVWWNQVGSGSVKYWMEQKSDRRLKENITDTAVKALDKINRLRMVA"
BASE COUNT          128 a          139 c           75 g          134 t
ORIGIN      
        1 gcaaccattc ttaatctgtt gattttgtcc aaggctttca cagctgtatc tgtgatgttc
       61 tcttttaagc gtctgtctga tttttgttcc atccaatact tcacgctacc gctaccgacc
      121 tgattccacc aaacaaccgc attccttccg cctttgggat tccaaccatc accaagcaca
      181 tctttacttc caagttcgat accatttgaa aacacaggag aacgagaaaa agtagtattc
      241 ccatagaagt ttgctctcga tgaattcgaa aaatccactt gatcataaaa accgacttca
      301 ttcctacagt acattttccc atcagtattg acgttccatg ctttaggtcc ggcatagttc
      361 caattatttc cccagttcgc ccagaaggct gtccggactc catgcccggc accattcccc
      421 ataccaacag agaactgatt gacacctgaa atccagcgac cgccaccctg gtcaaa
//
LOCUS       DAVKMJ010000132          452 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.133, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000132 DAVKMJ010000000
VERSION     DAVKMJ010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.133"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            1..452
                     /locus_tag="VW348_002199"
                     /pseudo
     CDS             1..452
                     /locus_tag="VW348_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          166 a           90 c           73 g          123 t
ORIGIN      
        1 tcttcttcta aaagccatta aactagctcg ttcgacctac tactatcact tgaaacagct
       61 agacaaaaca gataaggacc aagagcttaa agctgaaatt caatccatct ttatcgaaca
      121 caagggaaat tatgcttatc gtcggattta tttagaacta agaaatcgtg gttatctggt
      181 aaatcataaa agagttcaac acttgatgaa gtactcaatt tacaagctaa aacgcgacag
      241 aaacgaaaat attcttctca taaaggagac gttggcaaga aagcagagaa tctcattcaa
      301 ggccaatttg aaggctctaa aacaatggaa cagtgctaca cagatgtgac tgaatttgcc
      361 attccagtaa gtactcaaaa gctttactta tcaccagttt tagatggctt taatagcgaa
      421 attatcgcct ataatctttc aacttcaccc aa
//
LOCUS       DAVKMJ010000133          405 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.134, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000133 DAVKMJ010000000
VERSION     DAVKMJ010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.134"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            4..>405
                     /locus_tag="VW348_002200"
     CDS             4..>405
                     /locus_tag="VW348_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEU9747000.1"
                     /translation="MRIKQKRFADEYIISGNATEAYKKAGYRVSSDRVAGVEGHKLLK
                     NPKIKSYIDERLKQLDSEKIADQQEVLGYLTSVMRGETQEQTLISIGELGQTITDIDV
                     GAKDRIKAAELLGKRHRLWTDKVEADVSGTVV"
BASE COUNT          139 a           57 c          115 g           94 t
ORIGIN      
        1 ggattgagaa taaaacaaaa gagatttgca gatgagtaca tcatctcagg taatgcgacg
       61 gaagcctata agaaagcagg ttatcgtgtt tctagtgata gagtggcagg cgttgaagga
      121 cataagttac taaagaatcc taagattaaa agctatatag atgaacgact gaaacagctt
      181 gattctgaaa agattgcgga tcagcaagag gtcttaggtt atctaacttc agtcatgcga
      241 ggagagacgc aagaacagac cttgataagc attggagaac tagggcagac gattacggat
      301 atagatgtag gagctaaaga tagaatcaag gcggctgaac ttcttggtaa acggcatagg
      361 ctttggacgg ataaggtaga ggcggatgtt tctggaacgg tggtg
//
LOCUS       DAVKMJ010000134          401 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.135, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000134 DAVKMJ010000000
VERSION     DAVKMJ010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.135"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..186
                     /locus_tag="VW348_002201"
     CDS             <1..186
                     /locus_tag="VW348_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEU9747001.1"
                     /translation="KHEEIGLIAQEAETIVPRIVSRDPENPDGYLHIDYTALVPYLIK
                     AIQELNQKIEKMEKTIA"
BASE COUNT          163 a           70 c           71 g           97 t
ORIGIN      
        1 aaacatgagg agattggtct aatagctcaa gaggctgaaa ccatcgttcc aagaattgtc
       61 tcacgagatc ctgagaatcc agatggctat ctgcatattg actataccgc tttagttcct
      121 tacttaatca aggctattca agaattaaat caaaaaatag aaaaaatgga gaaaacaata
      181 gcatgaataa caacatgttg accaatatcg cactttaaag caattcagga gcttgctctt
      241 gaaaatagaa aacgaacaca cagattggag aacttagaaa atgaacacag aacagcttaa
      301 ccaagcctta caaatgacaa ttagtgaaat gtcaacaact tcaacaaatt cgatgattac
      361 aaataatatc ttgagtattc agttggatga gcaaagggaa g
//
LOCUS       DAVKMJ010000135          400 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.136, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000135 DAVKMJ010000000
VERSION     DAVKMJ010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..400
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.136"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..186
                     /locus_tag="VW348_002202"
     CDS             <1..186
                     /locus_tag="VW348_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9747002.1"
                     /translation="KHEEIGLIAQEAETIVPKIVSRDPENPDGYLHIDYTALVPYLIK
                     AIQELNQKIEKMEKTIA"
     gene            280..>400
                     /locus_tag="VW348_002203"
     CDS             280..>400
                     /locus_tag="VW348_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate reductase"
                     /protein_id="HEU9747003.1"
                     /translation="MNTEQLNQALQMTIREMSTTSTDSMITSNFLSIQLNEQRE"
BASE COUNT          161 a           72 c           71 g           96 t
ORIGIN      
        1 aaacatgagg agattggtct aatagctcaa gaggctgaaa ccatcgttcc aaaaattgtc
       61 tcacgagatc ctgagaatcc agatggctat ctgcatatcg actataccgc tttagttcct
      121 tacttaatca aggctattca agaattaaat caaaaaatag aaaaaatgga gaaaacaata
      181 gcatgaataa caacatgttg accaatatcg cacttaaagc aattcaggag cttgctcttg
      241 aaaatagaaa acgaacacac agattggaga acttagaaaa tgaacacaga acagcttaac
      301 caagccttac aaatgacaat tcgtgaaatg tcaacaactt caacagattc gatgattaca
      361 agtaatttct tgagtattca gttgaatgag caaagggaag
//
LOCUS       DAVKMJ010000136          397 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.137, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000136 DAVKMJ010000000
VERSION     DAVKMJ010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..397
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.137"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..299
                     /locus_tag="VW348_002204"
     CDS             <1..299
                     /locus_tag="VW348_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9747004.1"
                     /translation="PIEEAEKIAQSQVAWAILFILLFFIIIRYLIKTSDKREKKIMDL
                     HEQSKADSNRREERLMTHLEKTTTELTTITHAVGDIQKEMVRMNDRMEEIEKGE"
     gene            303..>397
                     /locus_tag="VW348_002205"
     CDS             303..>397
                     /locus_tag="VW348_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEU9747005.1"
                     /translation="MQQITEIITNGAISILVILAGIAVKAVKDYLV"
BASE COUNT          139 a           76 c           85 g           97 t
ORIGIN      
        1 tgccaattga agaagctgaa aaaatcgctc aaagtcaggt agcttgggcg attttgttta
       61 tcttgctttt ctttattatc attcgatatc ttatcaagac ttcggacaag cgagagaaga
      121 agattatgga tttgcacgag caatcaaagg ccgactctaa tagacgagaa gagcgtttga
      181 tgactcacct agaaaagacc actacagaat taaccacaat cactcacgcg gtcggagaca
      241 ttcaaaaaga aatggttcgc atgaacgacc gcatggaaga aatcgaaaaa ggagaataac
      301 aaatgcaaca aattactgaa atcattacta atggagcaat cagcatcctt gttattttgg
      361 ctggtatcgc agtcaaggca gtcaaggact acctggt
//
LOCUS       DAVKMJ010000137          384 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.138, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000137 DAVKMJ010000000
VERSION     DAVKMJ010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..384
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.138"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..>384
                     /locus_tag="VW348_002206"
     CDS             <1..>384
                     /locus_tag="VW348_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9747006.1"
                     /translation="DIASQIASYRQSVDGKFTDISSQITTYKQDVGGQISGLSNRLTS
                     SEQGTTTQISNISNRINSNKQGTDNQISNLKTQVATNKDNAERQMGRISDQVSANKAN
                     ADSQFANVTNQLARKVETTDFQRVK"
BASE COUNT          141 a           70 c           80 g           93 t
ORIGIN      
        1 agacatcgct agtcaaatcg ctagctatcg tcaatctgta gatggtaagt tcacggatat
       61 ttcaagtcag ataactactt ataagcaaga tgtgggcggt caaatcagtg gtctatcaaa
      121 tagacttaca agcagtgagc aaggaaccac tactcagatt tcaaatattt caaatcggat
      181 aaacagtaat aagcaaggca cagataatca gatttcaaat ttaaagactc aggtcgctac
      241 aaacaaggat aatgctgaac gacaaatggg tagaatatct gatcaggttt ctgcaaacaa
      301 agcgaatgct gatagtcaat ttgcgaatgt gaccaatcaa ctagcgcgaa aagtagagac
      361 tactgacttc cagcgtgtta agga
//
LOCUS       DAVKMJ010000138          379 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.139, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000138 DAVKMJ010000000
VERSION     DAVKMJ010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..379
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.139"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(<1..345)
                     /locus_tag="VW348_002207"
     CDS             complement(<1..345)
                     /locus_tag="VW348_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HEU9747007.1"
                     /translation="MWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVVSYD
                     DAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELLTIK
                     VPQPVQSGDMVRA"
BASE COUNT          101 a           88 c           77 g          113 t
ORIGIN      
        1 tgcacgaacc atgtctcctg attgaacggg ttgtgggact ttaatagtca atagttccat
       61 tggatttgga gcgcggtcga ttttattgcc tttggcatca tgcaaatctt caatataggt
      121 ttcaaaatga cggaaacctg gaccataaaa ctcaacttgg tccccttcgt taatgacgtt
      181 tcgttgacga atggttgctg tttgtgccgc atcatcataa gaaaccactt cagcgacaaa
      241 cttgtactca ggaattttac ggcgagcacc aaacaactgc tcattttcag atggtatacc
      301 gtagtagaaa cctgttgcca attcacgttg ggcaaccttc cacatctcgt ccaccaagtc
      361 ttgtttgata gcttcaaac
//
LOCUS       DAVKMJ010000139          351 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.140, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000139 DAVKMJ010000000
VERSION     DAVKMJ010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..351
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.140"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            complement(34..225)
                     /locus_tag="VW348_002208"
     CDS             complement(34..225)
                     /locus_tag="VW348_002208"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEU9747008.1"
                     /translation="MKSFKDFRESLTAEDMQAISAKANEATKQIDHTDGLQLGKVSGL
                     TSVITTIELLEKYHEWLHS"
BASE COUNT          107 a           61 c           67 g          116 t
ORIGIN      
        1 attttcagat agactcagaa gaatttaagc gtcttagcta tgaagccatt catgatactt
       61 ctcaagtaac tcaatagtag ttattacaga agtcaaacca ctgaccttcc ccagttgcaa
      121 tccgtctgta tggtcaatct gtttagtagc ttcattagct ttagcagaga tagcttgcat
      181 atcttcagct gttaaagatt ctcgaaaatc tttaaaggat ttcataaaaa ctcctccttt
      241 ctattggaat tttgactaaa acggtgagag gtcctagtcg agattattat agcaatttag
      301 gaggatatta catcggtctt gaggctgatt tttggaggca atattggaag a
//
LOCUS       DAVKMJ010000140          334 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00037941
            SAMN33606447-rid17939623.denovo.142, whole genome shotgun sequence.
ACCESSION   DAVKMJ010000140 DAVKMJ010000000
VERSION     DAVKMJ010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33606447
            Sequence Read Archive: SRR23727349
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001722391.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001722391.1
            Genome Coverage       :: 232x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:58:01
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,209
            CDSs (total)                      :: 2,159
            Genes (coding)                    :: 2,020
            CDSs (with protein)               :: 2,020
            Genes (RNA)                       :: 50
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 43
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 139
            CDSs (without protein)            :: 139
            Pseudo Genes (ambiguous residues) :: 0 of 139
            Pseudo Genes (frameshifted)       :: 72 of 139
            Pseudo Genes (incomplete)         :: 64 of 139
            Pseudo Genes (internal stop)      :: 40 of 139
            Pseudo Genes (multiple problems)  :: 30 of 139
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..334
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33606447-rid17939623.denovo.142"
                     /strain="AUSMDU00037941"
                     /serotype="19F"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2019"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST654"
     gene            <1..>334
                     /locus_tag="VW348_002209"
     CDS             <1..>334
                     /locus_tag="VW348_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HEU9747009.1"
                     /translation="ETYKPNVLHFCELLAEEEGIKLSDTTVRKILYKKNILSPKSHRK
                     TKKRVRKQAKLNLNQPLDNPILPTAKDFLEDPKKVHPSRPRKKFAGELIQMDASPHAW
                     FGPETTNL"
BASE COUNT          130 a           76 c           55 g           73 t
ORIGIN      
        1 atgaaacata taaaccaaat gtccttcatt tctgtgaatt actagctgaa gaagagggaa
       61 ttaagctctc tgatacaact gttagaaaaa tactctataa gaaaaacatc ctttctccta
      121 agtctcacag aaagacaaag aagagagtaa gaaaacaagc taaactgaac ctgaatcaac
      181 ccctagacaa tccaatctta ccgacggcta aagacttcct ggaagaccct aaaaaggtac
      241 atcctagtag acccagaaag aaatttgctg gagaactcat tcaaatggat gccagccctc
      301 atgcctggtt tggaccagaa accaccaact taca
//
